BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51034127 CCCCOCCOc1ccc(cc1)-c1ccc2N(CC(C)C)CCCC(=Cc2c1)C(=O)Nc1ccc(cc1)[S@@](=O)Cc1cncn1CCC InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/t50-/m0/s1 PNDKCRDVVKJPKG-DPDRHGIRSA-N 50422828 CENICRIVIROC::CENICRIVIROC MESYLATE::TAK-652::TBR-652 C-C chemokine receptor type 3 Homo sapiens 2400 ChEMBL 10.1021/jm0509703 10.7270/Q23N2303 16539392 Seto, M; Aikawa, K; Miyamoto, N; Aramaki, Y; Kanzaki, N; Takashima, K; Kuze, Y; Iizawa, Y; Baba, M; Shiraishi, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422828&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11285792 164151703 ZINC28569498 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251847 CNC(=O)c1ccnc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C25H30ClN5O3/c1-16-13-17(3-4-20(16)26)15-30-11-8-19(9-12-30)31-21(5-6-23(31)32)25(34)29-22-14-18(7-10-28-22)24(33)27-2/h3-4,7,10,13-14,19,21H,5-6,8-9,11-12,15H2,1-2H3,(H,27,33)(H,28,29,34)/t21-/m1/s1 WMXKEASINWPVKA-OAQYLSRUSA-N 123062 US8742115, 1 C-C chemokine receptor type 3 Homo sapiens 23.4 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123062&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966925 225149483 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251848 Cc1cccc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 InChI=1S/C24H29ClN4O2/c1-16-14-18(6-7-20(16)25)15-28-12-10-19(11-13-28)29-21(8-9-23(29)30)24(31)27-22-5-3-4-17(2)26-22/h3-7,14,19,21H,8-13,15H2,1-2H3,(H,26,27,31)/t21-/m1/s1 HGHIEIJMWUZYJZ-OAQYLSRUSA-N 123063 US8742115, 2 C-C chemokine receptor type 3 Homo sapiens 69.6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123063&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965997 225149484 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251849 COc1ccnc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C24H29ClN4O3/c1-16-13-17(3-4-20(16)25)15-28-11-8-18(9-12-28)29-21(5-6-23(29)30)24(31)27-22-14-19(32-2)7-10-26-22/h3-4,7,10,13-14,18,21H,5-6,8-9,11-12,15H2,1-2H3,(H,26,27,31)/t21-/m1/s1 HHMXLFOQDCIKTQ-OAQYLSRUSA-N 123064 US8742115, 3 C-C chemokine receptor type 3 Homo sapiens 46.5 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123064&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966927 225149485 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251850 Cc1ccnc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C24H29ClN4O2/c1-16-7-10-26-22(13-16)27-24(31)21-5-6-23(30)29(21)19-8-11-28(12-9-19)15-18-3-4-20(25)17(2)14-18/h3-4,7,10,13-14,19,21H,5-6,8-9,11-12,15H2,1-2H3,(H,26,27,31)/t21-/m1/s1 PHHYBEHODHLJBX-OAQYLSRUSA-N 123065 US8742115, 4 C-C chemokine receptor type 3 Homo sapiens 67.5 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123065&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966928 225149486 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251851 CCc1ccnc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C25H31ClN4O2/c1-3-18-8-11-27-23(15-18)28-25(32)22-6-7-24(31)30(22)20-9-12-29(13-10-20)16-19-4-5-21(26)17(2)14-19/h4-5,8,11,14-15,20,22H,3,6-7,9-10,12-13,16H2,1-2H3,(H,27,28,32)/t22-/m1/s1 JCTNMMSJBUIHJQ-JOCHJYFZSA-N 123066 US8742115, 5 C-C chemokine receptor type 3 Homo sapiens 196.6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123066&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790198 225149487 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251852 CNC(=O)c1cccc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 InChI=1S/C25H30ClN5O3/c1-16-14-17(6-7-19(16)26)15-30-12-10-18(11-13-30)31-21(8-9-23(31)32)25(34)29-22-5-3-4-20(28-22)24(33)27-2/h3-7,14,18,21H,8-13,15H2,1-2H3,(H,27,33)(H,28,29,34)/t21-/m1/s1 NSDKXKSBLQGVMA-OAQYLSRUSA-N 123067 US8742115, 6 C-C chemokine receptor type 3 Homo sapiens 72 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123067&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115364 225149488 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251853 CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C26H32ClN5O3/c1-16-12-18(4-5-21(16)27)15-31-10-8-20(9-11-31)32-22(6-7-24(32)33)26(35)30-23-14-19(25(34)28-3)13-17(2)29-23/h4-5,12-14,20,22H,6-11,15H2,1-3H3,(H,28,34)(H,29,30,35)/t22-/m1/s1 DRTNQHBPTOBJJH-JOCHJYFZSA-N 123068 US10213421, Example 1::US11612596, Example 1.::US8742115, 7 C-C chemokine receptor type 3 Homo sapiens 10.4 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123068&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965995 225149489 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251854 CN(C)C(=O)c1ccnc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C26H32ClN5O3/c1-17-14-18(4-5-21(17)27)16-31-12-9-20(10-13-31)32-22(6-7-24(32)33)25(34)29-23-15-19(8-11-28-23)26(35)30(2)3/h4-5,8,11,14-15,20,22H,6-7,9-10,12-13,16H2,1-3H3,(H,28,29,34)/t22-/m1/s1 HFIAMUNOIKFEAZ-JOCHJYFZSA-N 123069 US8742115, 8 C-C chemokine receptor type 3 Homo sapiens 8.5 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123069&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965996 225149490 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251855 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N1CCCC1 InChI=1S/C29H36ClN5O3/c1-19-15-21(5-6-24(19)30)18-33-13-9-23(10-14-33)35-25(7-8-27(35)36)28(37)32-26-17-22(16-20(2)31-26)29(38)34-11-3-4-12-34/h5-6,15-17,23,25H,3-4,7-14,18H2,1-2H3,(H,31,32,37)/t25-/m1/s1 MVFQZFGSHLSESC-RUZDIDTESA-N 123070 US8742115, 9 C-C chemokine receptor type 3 Homo sapiens 0.9 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123070&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 46931923 225149491 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251856 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N1CCOCC1 InChI=1S/C29H36ClN5O4/c1-19-15-21(3-4-24(19)30)18-33-9-7-23(8-10-33)35-25(5-6-27(35)36)28(37)32-26-17-22(16-20(2)31-26)29(38)34-11-13-39-14-12-34/h3-4,15-17,23,25H,5-14,18H2,1-2H3,(H,31,32,37)/t25-/m1/s1 BLZYACUWHWYCOK-RUZDIDTESA-N 123071 US8742115, 10 C-C chemokine receptor type 3 Homo sapiens 6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123071&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966929 225149492 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251857 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C27H34ClN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1 DWKNOLCXIFYNFV-HSZRJFAPSA-N 123072 US10213421, Example 2::US11612596, Example 2.::US8742115, 11 C-C chemokine receptor type 3 Homo sapiens 3.2 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123072&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59534386 225149493 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251858 Cc1cc(CN2CCC(CC2)N2[C@H](CCC2=O)C(=O)Nc2cc(ccn2)C(=O)N2CCCC2)ccc1Cl InChI=1S/C28H34ClN5O3/c1-19-16-20(4-5-23(19)29)18-32-14-9-22(10-15-32)34-24(6-7-26(34)35)27(36)31-25-17-21(8-11-30-25)28(37)33-12-2-3-13-33/h4-5,8,11,16-17,22,24H,2-3,6-7,9-10,12-15,18H2,1H3,(H,30,31,36)/t24-/m1/s1 VFUAKEBITBBJCN-XMMPIXPASA-N 123073 US8742115, 12 C-C chemokine receptor type 3 Homo sapiens 4.7 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123073&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115023 225149494 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251859 Cc1cc(CN2CCC(CC2)N2[C@H](CCC2=O)C(=O)Nc2cc(ccn2)C(=O)N2CCOCC2)ccc1Cl InChI=1S/C28H34ClN5O4/c1-19-16-20(2-3-23(19)29)18-32-10-7-22(8-11-32)34-24(4-5-26(34)35)27(36)31-25-17-21(6-9-30-25)28(37)33-12-14-38-15-13-33/h2-3,6,9,16-17,22,24H,4-5,7-8,10-15,18H2,1H3,(H,30,31,36)/t24-/m1/s1 DLCRLFAACGTYEO-XMMPIXPASA-N 123074 US8742115, 13 C-C chemokine receptor type 3 Homo sapiens 19.1 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123074&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67114884 225149495 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251860 CN(C(=O)[C@H]1CCC(=O)N1C1CCN(Cc2ccc(Cl)c(C)c2)CC1)c1ccccn1 InChI=1S/C24H29ClN4O2/c1-17-15-18(6-7-20(17)25)16-28-13-10-19(11-14-28)29-21(8-9-23(29)30)24(31)27(2)22-5-3-4-12-26-22/h3-7,12,15,19,21H,8-11,13-14,16H2,1-2H3/t21-/m1/s1 MMAXUOFAKLGZCQ-OAQYLSRUSA-N 123075 US8742115, 14 C-C chemokine receptor type 3 Homo sapiens 1401.6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123075&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790201 225149496 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251861 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC1CC1 InChI=1S/C29H36ClN5O3/c1-18-13-21(5-6-24(18)30)17-34-11-9-23(10-12-34)35-25(7-8-27(35)36)29(38)33-26-15-22(14-19(2)32-26)28(37)31-16-20-3-4-20/h5-6,13-15,20,23,25H,3-4,7-12,16-17H2,1-2H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 OUGOQNYEXLDDNI-RUZDIDTESA-N 123076 US10213421, Example 3::US11612596, Example 3.::US8742115, 15 C-C chemokine receptor type 3 Homo sapiens 3.5 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123076&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966926 225149497 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251862 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N1CCC1 InChI=1S/C28H34ClN5O3/c1-18-14-20(4-5-23(18)29)17-32-12-8-22(9-13-32)34-24(6-7-26(34)35)27(36)31-25-16-21(15-19(2)30-25)28(37)33-10-3-11-33/h4-5,14-16,22,24H,3,6-13,17H2,1-2H3,(H,30,31,36)/t24-/m1/s1 WQIBZQVCVFDQOC-XMMPIXPASA-N 123077 US8742115, 16 C-C chemokine receptor type 3 Homo sapiens 6.8 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123077&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966995 225149498 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251863 CC(C)CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)16-31-28(37)22-14-20(4)32-26(15-22)33-29(38)25-7-8-27(36)35(25)23-9-11-34(12-10-23)17-21-5-6-24(30)19(3)13-21/h5-6,13-15,18,23,25H,7-12,16-17H2,1-4H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 FNTAOKQFFGXTKD-RUZDIDTESA-N 123078 US10213421, Example 4::US11612596, Example 4.::US8742115, 17 C-C chemokine receptor type 3 Homo sapiens 4.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123078&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115103 225149499 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251864 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC(F)F InChI=1S/C27H32ClF2N5O3/c1-16-11-18(3-4-21(16)28)15-34-9-7-20(8-10-34)35-22(5-6-25(35)36)27(38)33-24-13-19(12-17(2)32-24)26(37)31-14-23(29)30/h3-4,11-13,20,22-23H,5-10,14-15H2,1-2H3,(H,31,37)(H,32,33,38)/t22-/m1/s1 GSSCURHTCHTCBR-JOCHJYFZSA-N 123079 US10213421, Example 5::US11612596, Example 5.::US8742115, 18 C-C chemokine receptor type 3 Homo sapiens 4.6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123079&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966996 225149500 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251865 CCC(C)NC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-5-19(3)32-28(37)22-15-20(4)31-26(16-22)33-29(38)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)18(2)14-21/h6-7,14-16,19,23,25H,5,8-13,17H2,1-4H3,(H,32,37)(H,31,33,38)/t19?,25-/m1/s1 YCXJKGVLGXQFPR-OPEAARRCSA-N 123080 US10213421, Example 6::US11612596, Example 6.::US8742115, 19 C-C chemokine receptor type 3 Homo sapiens 4 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123080&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115149 225149501 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251866 CCC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C30H40ClN5O3/c1-6-21(4)34(5)30(39)23-16-20(3)32-27(17-23)33-29(38)26-9-10-28(37)36(26)24-11-13-35(14-12-24)18-22-7-8-25(31)19(2)15-22/h7-8,15-17,21,24,26H,6,9-14,18H2,1-5H3,(H,32,33,38)/t21?,26-/m1/s1 XQJLPJZZKJPBNB-ZTDHTWSHSA-N 123081 US10213421, Example 7::US11612596, Example 7.::US8742115, 21 C-C chemokine receptor type 3 Homo sapiens 5.2 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790202 225149502 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251867 CC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)33(5)29(38)22-15-20(4)31-26(16-22)32-28(37)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)19(3)14-21/h6-7,14-16,18,23,25H,8-13,17H2,1-5H3,(H,31,32,37)/t25-/m1/s1 DYNUOWFKWPVKKC-RUZDIDTESA-N 123082 US10213421, Example 8::US11612596, Example 8.::US8742115, 22 C-C chemokine receptor type 3 Homo sapiens 2.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67114949 225149503 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251868 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NC1CCC1 InChI=1S/C29H36ClN5O3/c1-18-14-20(6-7-24(18)30)17-34-12-10-23(11-13-34)35-25(8-9-27(35)36)29(38)33-26-16-21(15-19(2)31-26)28(37)32-22-4-3-5-22/h6-7,14-16,22-23,25H,3-5,8-13,17H2,1-2H3,(H,32,37)(H,31,33,38)/t25-/m1/s1 VLDHAXJQQANHCX-RUZDIDTESA-N 123083 US10213421, Example 9::US11612596, Example 9.::US8742115, 23 C-C chemokine receptor type 3 Homo sapiens 4.2 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123083&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68029259 225149504 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251869 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Br)c(C)c3)CC2)c1 InChI=1S/C27H34BrN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1 HITKWWBAAMNPJX-HSZRJFAPSA-N 123084 US8742115, 24 C-C chemokine receptor type 3 Homo sapiens 5.8 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123084&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966997 225149505 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251870 CCc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C InChI=1S/C28H36ClN5O3/c1-5-21-15-20(28(37)32(3)4)16-25(30-21)31-27(36)24-8-9-26(35)34(24)22-10-12-33(13-11-22)17-19-6-7-23(29)18(2)14-19/h6-7,14-16,22,24H,5,8-13,17H2,1-4H3,(H,30,31,36)/t24-/m1/s1 PWECZSTXXURXCH-XMMPIXPASA-N 123085 US8742115, 25 C-C chemokine receptor type 3 Homo sapiens 8.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123085&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965994 225149506 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251871 COc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C InChI=1S/C27H34ClN5O4/c1-17-13-18(5-6-21(17)28)16-32-11-9-20(10-12-32)33-22(7-8-25(33)34)26(35)30-23-14-19(27(36)31(2)3)15-24(29-23)37-4/h5-6,13-15,20,22H,7-12,16H2,1-4H3,(H,29,30,35)/t22-/m1/s1 RBMGDTKBYRBBOQ-JOCHJYFZSA-N 123086 US8742115, 26 C-C chemokine receptor type 3 Homo sapiens 231.6 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123086&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966998 225149507 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251872 CCCCc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C InChI=1S/C30H40ClN5O3/c1-5-6-7-23-17-22(30(39)34(3)4)18-27(32-23)33-29(38)26-10-11-28(37)36(26)24-12-14-35(15-13-24)19-21-8-9-25(31)20(2)16-21/h8-9,16-18,24,26H,5-7,10-15,19H2,1-4H3,(H,32,33,38)/t26-/m1/s1 GMZNPEVSWOSGIT-AREMUKBSSA-N 123087 US8742115, 27 C-C chemokine receptor type 3 Homo sapiens 413.8 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123087&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68028909 225149508 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251873 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)c1 InChI=1S/C26H31Cl2N5O3/c1-16-12-18(26(36)31(2)3)14-23(29-16)30-25(35)22-6-7-24(34)33(22)19-8-10-32(11-9-19)15-17-4-5-20(27)21(28)13-17/h4-5,12-14,19,22H,6-11,15H2,1-3H3,(H,29,30,35)/t22-/m1/s1 XKVUMIOOBCRTBK-JOCHJYFZSA-N 123088 US8742115, 28 C-C chemokine receptor type 3 Homo sapiens 17.8 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123088&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967062 225149509 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251874 CC(C)c1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)N(C)C InChI=1S/C29H38ClN5O3/c1-18(2)24-15-21(29(38)33(4)5)16-26(31-24)32-28(37)25-8-9-27(36)35(25)22-10-12-34(13-11-22)17-20-6-7-23(30)19(3)14-20/h6-7,14-16,18,22,25H,8-13,17H2,1-5H3,(H,31,32,37)/t25-/m1/s1 RSBUVLAGKFKMCT-RUZDIDTESA-N 123089 US8742115, 29 C-C chemokine receptor type 3 Homo sapiens 4.1 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123089&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68028908 225149510 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251875 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(F)c(C)c3)CC2)c1 InChI=1S/C27H34FN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1 DRTQKAKOLNLJIV-HSZRJFAPSA-N 123090 US8742115, 30 C-C chemokine receptor type 3 Homo sapiens 70.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123090&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966999 225149511 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251876 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(c3)C(F)(F)F)CC2)c1 InChI=1S/C27H31ClF3N5O3/c1-16-12-18(26(39)34(2)3)14-23(32-16)33-25(38)22-6-7-24(37)36(22)19-8-10-35(11-9-19)15-17-4-5-21(28)20(13-17)27(29,30)31/h4-5,12-14,19,22H,6-11,15H2,1-3H3,(H,32,33,38)/t22-/m1/s1 UGHANIQBLJXNGL-JOCHJYFZSA-N 123091 US8742115, 31 C-C chemokine receptor type 3 Homo sapiens 87.2 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123091&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967063 225149512 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251877 CN(C)C(=O)c1cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)nc(c1)C1CC1 InChI=1S/C29H36ClN5O3/c1-18-14-19(4-7-23(18)30)17-34-12-10-22(11-13-34)35-25(8-9-27(35)36)28(37)32-26-16-21(29(38)33(2)3)15-24(31-26)20-5-6-20/h4,7,14-16,20,22,25H,5-6,8-13,17H2,1-3H3,(H,31,32,37)/t25-/m1/s1 PSQWVAHRODEKJJ-RUZDIDTESA-N 123092 US8742115, 32 C-C chemokine receptor type 3 Homo sapiens 2.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123092&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967064 225149513 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251878 CCc1cc(CN2CCC(CC2)N2[C@H](CCC2=O)C(=O)Nc2cc(cc(C)n2)C(=O)N(C)C)ccc1Cl InChI=1S/C28H36ClN5O3/c1-5-20-15-19(6-7-23(20)29)17-33-12-10-22(11-13-33)34-24(8-9-26(34)35)27(36)31-25-16-21(14-18(2)30-25)28(37)32(3)4/h6-7,14-16,22,24H,5,8-13,17H2,1-4H3,(H,30,31,36)/t24-/m1/s1 KQCOGJOTIOGMPG-XMMPIXPASA-N 123093 US8742115, 33 C-C chemokine receptor type 3 Homo sapiens 7.9 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123093&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115945 225149514 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251879 CN(C)C(=O)c1cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)nc(c1)C#C InChI=1S/C28H32ClN5O3/c1-5-21-15-20(28(37)32(3)4)16-25(30-21)31-27(36)24-8-9-26(35)34(24)22-10-12-33(13-11-22)17-19-6-7-23(29)18(2)14-19/h1,6-7,14-16,22,24H,8-13,17H2,2-4H3,(H,30,31,36)/t24-/m1/s1 IBLWQMSABLXXHK-XMMPIXPASA-N 123094 US8742115, 34 C-C chemokine receptor type 3 Homo sapiens 7.9 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123094&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967065 225149515 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251880 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3cc(C)c(Cl)c(C)c3)CC2)c1 InChI=1S/C28H36ClN5O3/c1-17-12-20(13-18(2)26(17)29)16-33-10-8-22(9-11-33)34-23(6-7-25(34)35)27(36)31-24-15-21(14-19(3)30-24)28(37)32(4)5/h12-15,22-23H,6-11,16H2,1-5H3,(H,30,31,36)/t23-/m1/s1 TWVMIWIAGAWUTR-HSZRJFAPSA-N 123095 US8742115, 35 C-C chemokine receptor type 3 Homo sapiens 61.3 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123095&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790203 225149516 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 251881 CCN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C28H36ClN5O3/c1-5-32(4)28(37)21-15-19(3)30-25(16-21)31-27(36)24-8-9-26(35)34(24)22-10-12-33(13-11-22)17-20-6-7-23(29)18(2)14-20/h6-7,14-16,22,24H,5,8-13,17H2,1-4H3,(H,30,31,36)/t24-/m1/s1 KSQBKUICOIKPNV-XMMPIXPASA-N 123096 US10213421, Example 10::US11612596, Example 10.::US8742115, 36 C-C chemokine receptor type 3 Homo sapiens 1.7 US Patent 10.7270/Q2V986QD aid1800470 US8742115 Frank, M; Haeberle, H; Henry, M; Pachur, T; Santagostino, M; Stertz, U; Trebing, T; Werthmann, U Boehringer Ingelheim International GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123096&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967066 225149517 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014057 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens >330 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014062 CCn1ccnc1[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C24H22N4O3/c1-2-27-15-14-25-23(27)22(16-17-10-12-19(13-11-17)28(30)31)26-24(29)21-9-5-7-18-6-3-4-8-20(18)21/h3-15,22H,2,16H2,1H3,(H,26,29)/t22-/m0/s1 SPCKTJSHKWCWJB-QFIPXVFZSA-N 50100056 CHEMBL287538::Naphthalene-1-carboxylic acid [(S)-1-(1-ethyl-1H-imidazol-2-yl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 17000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100056&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281793 103996872 CHEMBL287538 ZINC29231833 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016796 COc1cccc(NC(=O)N2CCNC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H33FN4O2/c1-32-24-4-2-3-22(16-24)28-25(31)30-14-11-27-23(18-30)17-29-12-9-20(10-13-29)15-19-5-7-21(26)8-6-19/h2-8,16,20,23,27H,9-15,17-18H2,1H3,(H,28,31) MYEGDSXUBNEVSB-UHFFFAOYSA-N 50115015 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperazine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL54273 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115015&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509697 104009003 CHEMBL54273 ZINC22924703 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016798 CCCC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C29H41N3O3/c1-3-4-14-28(34)27-20-24(19-23-10-6-5-7-11-23)15-18-32(27)17-9-16-30-29(35)31-26-13-8-12-25(21-26)22(2)33/h5-8,10-13,21,24,27-28,34H,3-4,9,14-20H2,1-2H3,(H2,30,31,35)/t24-,27-,28+/m1/s1 UIBIFUUBDLVHTJ-RTVRTQBESA-N 50115047 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-pentyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50233 C-C chemokine receptor type 3 Homo sapiens 1.000 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115047&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295536 104009035 CHEMBL50233 ZINC13443681 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016800 CC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O3/c1-3-26(32)25-18-22(17-21-9-5-4-6-10-21)13-16-30(25)15-8-14-28-27(33)29-24-12-7-11-23(19-24)20(2)31/h4-7,9-12,19,22,25-26,32H,3,8,13-18H2,1-2H3,(H2,28,29,33)/t22-,25-,26+/m1/s1 UEKNCACYTQCRSI-RCXJIHSJSA-N 50115012 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50593 C-C chemokine receptor type 3 Homo sapiens 8.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115012&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9868459 104009000 CHEMBL50593 3492 ZINC13443656 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016801 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C23H27FN4O/c24-21-7-5-18(6-8-21)15-19-9-13-28(14-10-19)12-2-11-26-23(29)27-22-4-1-3-20(16-22)17-25/h1,3-8,16,19H,2,9-15H2,(H2,26,27,29) JHJVGMKZQAABON-UHFFFAOYSA-N 50115021 1-(3-Cyano-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43677 C-C chemokine receptor type 3 Homo sapiens 80 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393430 104009009 CHEMBL43677 ZINC13443482 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016802 COc1cccc(NC(=O)N2CCOC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H32FN3O3/c1-31-23-4-2-3-22(16-23)27-25(30)29-13-14-32-24(18-29)17-28-11-9-20(10-12-28)15-19-5-7-21(26)8-6-19/h2-8,16,20,24H,9-15,17-18H2,1H3,(H,27,30) CBNWNPGNUKPULD-UHFFFAOYSA-N 50115053 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-morpholine-4-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL51584 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115053&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509695 104009041 CHEMBL51584 ZINC13443618 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50022075 COc1cc(NC(=O)N[C@@H](CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)[C@H](C)O)cc(OC)c1OC InChI=1S/C28H38ClN3O5/c1-17(33)24(31-28(34)30-21-14-25(35-2)27(37-4)26(15-21)36-3)16-32-22-9-10-23(32)13-19(12-22)11-18-5-7-20(29)8-6-18/h5-8,14-15,17,19,22-24,33H,9-13,16H2,1-4H3,(H2,30,31,34)/t17-,19?,22?,23?,24-/m0/s1 RQFRVKNYCADNRP-GBDXXHDTSA-N 50133793 1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-hydroxy-propyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL431670 C-C chemokine receptor type 3 Homo sapiens 8.2 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133793&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346210 104024547 CHEMBL431670 ZINC27180458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50022118 CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3/p+1/b21-8+ VQHKDCUXFKNNMT-ODCIPOBUSA-O 50451624 CHEMBL331897 C-C chemokine receptor type 3 Homo sapiens 0.580000 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451624&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918497 225145411 CHEMBL331897 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50022121 COc1cc(NC(=O)N[C@H](C)CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)cc(OC)c1OC InChI=1S/C27H36ClN3O4/c1-17(29-27(32)30-21-14-24(33-2)26(35-4)25(15-21)34-3)16-31-22-9-10-23(31)13-19(12-22)11-18-5-7-20(28)8-6-18/h5-8,14-15,17,19,22-23H,9-13,16H2,1-4H3,(H2,29,30,32)/t17-,19?,22?,23?/m1/s1 HLDKNBAUHHXAGK-UINAOQCUSA-N 50133796 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL121905 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133796&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346194 104024550 CHEMBL121905 ZINC13553781 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115075 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115076 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24+,27-/m1/s1 ASRDPULQBHFPGU-RWCIVJTCSA-N 50163645 1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[(R)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL370082 C-C chemokine receptor type 3 Homo sapiens 0.364000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163645&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11385766 104049628 CHEMBL370082 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115077 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3nc4c(Cl)cccc4s3)C2)cc1 InChI=1S/C27H32ClFN4OS/c28-22-7-3-9-24-25(22)31-27(35-24)32-26(34)30-23-8-2-1-6-20(23)17-33-14-4-5-19(16-33)15-18-10-12-21(29)13-11-18/h3,7,9-13,19-20,23H,1-2,4-6,8,14-17H2,(H2,30,31,32,34)/t19-,20-,23+/m0/s1 CCWUVBRDCQPCJX-SXWKCWPCSA-N 50163660 1-(4-Chloro-benzothiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195790 C-C chemokine receptor type 3 Homo sapiens 0.090000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163660&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11214474 104049643 CHEMBL195790 ZINC03976345 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115078 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115080 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.500000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115081 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)ccc1F InChI=1S/C28H35F2N3O2/c1-19(34)25-16-24(12-13-26(25)30)31-28(35)32-27-7-3-2-6-22(27)18-33-14-4-5-21(17-33)15-20-8-10-23(29)11-9-20/h8-13,16,21-22,27H,2-7,14-15,17-18H2,1H3,(H2,31,32,35)/t21-,22-,27+/m0/s1 XXFNYXARXWCONM-BCQCSXDESA-N 50163661 1-(3-Acetyl-4-fluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL365820 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163661&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11340670 104049644 CHEMBL365820 ZINC13613306 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115082 Cc1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H36FN3O/c1-20-7-2-4-10-25(20)29-27(32)30-26-11-5-3-9-23(26)19-31-16-6-8-22(18-31)17-21-12-14-24(28)15-13-21/h2,4,7,10,12-15,22-23,26H,3,5-6,8-9,11,16-19H2,1H3,(H2,29,30,32)/t22-,23-,26+/m0/s1 AUZDFHZZRBZEPU-JCYRPKCISA-N 50163671 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-o-tolyl-urea::CHEMBL176077 C-C chemokine receptor type 3 Homo sapiens >100 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163671&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11154845 104049654 CHEMBL176077 ZINC13613257 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115083 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.800000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115084 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(F)cc3)C2)cc1 InChI=1S/C26H33F2N3O/c27-22-9-7-19(8-10-22)16-20-4-3-15-31(17-20)18-21-5-1-2-6-25(21)30-26(32)29-24-13-11-23(28)12-14-24/h7-14,20-21,25H,1-6,15-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 NKRJCSZTCFOFKV-STWLZBDKSA-N 50163654 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-fluoro-phenyl)-urea::CHEMBL194141 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163654&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11316656 104049637 CHEMBL194141 ZINC03976344 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115085 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(Br)cc3)C2)cc1 InChI=1S/C26H33BrFN3O/c27-22-9-13-24(14-10-22)29-26(32)30-25-6-2-1-5-21(25)18-31-15-3-4-20(17-31)16-19-7-11-23(28)12-8-19/h7-14,20-21,25H,1-6,15-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 XOLRUKHPGCIPJW-STWLZBDKSA-N 50163646 1-(4-Bromo-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193442 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163646&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11179592 104049629 CHEMBL193442 ZINC13613294 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115086 COc1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H36FN3O2/c1-33-26-11-5-4-10-25(26)30-27(32)29-24-9-3-2-8-22(24)19-31-16-6-7-21(18-31)17-20-12-14-23(28)15-13-20/h4-5,10-15,21-22,24H,2-3,6-9,16-19H2,1H3,(H2,29,30,32)/t21-,22-,24+/m0/s1 UKGNFGQNYLRGJL-WPFOTENUSA-N 50163651 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-methoxy-phenyl)-urea::CHEMBL175634 C-C chemokine receptor type 3 Homo sapiens 115 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163651&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11363005 104049634 CHEMBL175634 ZINC13613259 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115087 Cn1nnnc1-c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C30H38FN11O/c1-40-28(34-36-38-40)23-15-24(29-35-37-39-41(29)2)17-26(16-23)32-30(43)33-27-8-4-3-7-22(27)19-42-13-5-6-21(18-42)14-20-9-11-25(31)12-10-20/h9-12,15-17,21-22,27H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,43)/t21-,22-,27+/m0/s1 DRZLAUYXLXUZDX-BCQCSXDESA-N 50163678 1-[3,5-Bis-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL382108 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163678&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11169258 104049661 CHEMBL382108 ZINC03976347 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115088 Cc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1F InChI=1S/C27H35F2N3O/c1-19-8-13-24(16-25(19)29)30-27(33)31-26-7-3-2-6-22(26)18-32-14-4-5-21(17-32)15-20-9-11-23(28)12-10-20/h8-13,16,21-22,26H,2-7,14-15,17-18H2,1H3,(H2,30,31,33)/t21-,22-,26+/m0/s1 MQYFAGPXNWMFSN-AOJNWGRGSA-N 50163648 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-fluoro-4-methyl-phenyl)-urea::CHEMBL363166 C-C chemokine receptor type 3 Homo sapiens 35 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163648&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11442439 104049631 CHEMBL363166 ZINC13613274 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115089 CC(=O)c1cccc(NC(=O)NN2CCCCC2Cc2ccc(F)cc2)c1 InChI=1S/C21H24FN3O2/c1-15(26)17-5-4-6-19(14-17)23-21(27)24-25-12-3-2-7-20(25)13-16-8-10-18(22)11-9-16/h4-6,8-11,14,20H,2-3,7,12-13H2,1H3,(H2,23,24,27) SOEZEWJTMGDYDZ-UHFFFAOYSA-N 50163638 1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperidin-1-yl]-urea::CHEMBL368683 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163638&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387842 104049621 CHEMBL368683 ZINC28112350 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115090 Cc1nnnn1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-20-32-33-34-36(20)26-9-4-8-25(17-26)30-28(37)31-27-10-3-2-7-23(27)19-35-15-5-6-22(18-35)16-21-11-13-24(29)14-12-21/h4,8-9,11-14,17,22-23,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t22-,23-,27+/m0/s1 QLTHBTHVYYXPHB-VMODYCNZSA-N 50163656 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(5-methyl-tetrazol-1-yl)-phenyl]-urea::CHEMBL195555 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163656&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11454941 104049639 CHEMBL195555 ZINC13613361 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115091 CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(C)=O)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C30H33FN4O3/c1-20(36)23-5-3-6-25(18-23)33-30(38)34-28-8-4-7-26(29(37)32-2)27(28)19-35-15-13-22(14-16-35)17-21-9-11-24(31)12-10-21/h3-12,18,22H,13-17,19H2,1-2H3,(H,32,37)(H2,33,34,38) AYLIGBDQTHFVLJ-UHFFFAOYSA-N 50117461 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL123611 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117461&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9892753 104011017 CHEMBL123611 ZINC03974016 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115092 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115097 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C30H38FN3O3/c1-20(35)25-15-26(21(2)36)17-28(16-25)32-30(37)33-29-8-4-3-7-24(29)19-34-13-5-6-23(18-34)14-22-9-11-27(31)12-10-22/h9-12,15-17,23-24,29H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,37)/t23-,24-,29+/m0/s1 XNECWHFEDUTGHE-NDIVSWGXSA-N 50163650 1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193575 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163650&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11409583 104049633 CHEMBL193575 ZINC13613303 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115100 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccccc3)C2)cc1 InChI=1S/C26H34FN3O/c27-23-14-12-20(13-15-23)17-21-7-6-16-30(18-21)19-22-8-4-5-11-25(22)29-26(31)28-24-9-2-1-3-10-24/h1-3,9-10,12-15,21-22,25H,4-8,11,16-19H2,(H2,28,29,31)/t21-,22-,25+/m0/s1 WWCDUCXBCODJGF-WRALFONMSA-N 50163667 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-phenyl-urea::CHEMBL362466 C-C chemokine receptor type 3 Homo sapiens 17 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163667&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11430170 104049650 CHEMBL362466 ZINC13613255 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115113 COc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 InChI=1S/C27H36FN3O2/c1-33-25-14-12-24(13-15-25)29-27(32)30-26-7-3-2-6-22(26)19-31-16-4-5-21(18-31)17-20-8-10-23(28)11-9-20/h8-15,21-22,26H,2-7,16-19H2,1H3,(H2,29,30,32)/t21-,22-,26+/m0/s1 OEKONQSOWUDFGV-AOJNWGRGSA-N 50163632 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methoxy-phenyl)-urea::CHEMBL194601 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163632&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11363006 104049615 CHEMBL194601 ZINC13613262 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115114 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115115 Cc1nnnn1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-20-32-33-34-36(20)26-9-4-8-25(17-26)30-28(37)31-27-10-3-2-7-23(27)19-35-15-5-6-22(18-35)16-21-11-13-24(29)14-12-21/h4,8-9,11-14,17,22-23,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t22-,23-,27+/m0/s1 QLTHBTHVYYXPHB-VMODYCNZSA-N 50163656 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(5-methyl-tetrazol-1-yl)-phenyl]-urea::CHEMBL195555 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163656&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11454941 104049639 CHEMBL195555 ZINC13613361 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115116 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)ccc1F InChI=1S/C28H35F2N3O2/c1-19(34)25-16-24(12-13-26(25)30)31-28(35)32-27-7-3-2-6-22(27)18-33-14-4-5-21(17-33)15-20-8-10-23(29)11-9-20/h8-13,16,21-22,27H,2-7,14-15,17-18H2,1H3,(H2,31,32,35)/t21-,22-,27+/m0/s1 XXFNYXARXWCONM-BCQCSXDESA-N 50163661 1-(3-Acetyl-4-fluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL365820 C-C chemokine receptor type 3 Homo sapiens 0.015000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163661&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11340670 104049644 CHEMBL365820 ZINC13613306 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115117 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24+,27-/m1/s1 ASRDPULQBHFPGU-RWCIVJTCSA-N 50163645 1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[(R)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL370082 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163645&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11385766 104049628 CHEMBL370082 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115118 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ncc4c3)C2)cc1 InChI=1S/C27H34FN5O/c28-23-9-7-19(8-10-23)14-20-4-3-13-33(17-20)18-21-5-1-2-6-25(21)31-27(34)30-24-11-12-26-22(15-24)16-29-32-26/h7-12,15-16,20-21,25H,1-6,13-14,17-18H2,(H,29,32)(H2,30,31,34)/t20-,21-,25+/m0/s1 MLPROCBAZKTJHS-STWLZBDKSA-N 50410322 CHEMBL2113077 C-C chemokine receptor type 3 Homo sapiens 0.045000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410322&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11488078 163359346 CHEMBL2113077 ZINC13613319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115119 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 0.500000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115120 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.034000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115121 Cn1nnnc1-c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C30H38FN11O/c1-40-28(34-36-38-40)23-15-24(29-35-37-39-41(29)2)17-26(16-23)32-30(43)33-27-8-4-3-7-22(27)19-42-13-5-6-21(18-42)14-20-9-11-25(31)12-10-20/h9-12,15-17,21-22,27H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,43)/t21-,22-,27+/m0/s1 DRZLAUYXLXUZDX-BCQCSXDESA-N 50163678 1-[3,5-Bis-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL382108 C-C chemokine receptor type 3 Homo sapiens 0.042000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163678&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11169258 104049661 CHEMBL382108 ZINC03976347 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115122 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 0.030000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115123 Cn1nnnc1-c1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-10-14-25(15-11-22)30-28(37)31-26-7-3-2-6-23(26)19-36-16-4-5-21(18-36)17-20-8-12-24(29)13-9-20/h8-15,21,23,26H,2-7,16-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 LWUHFNIVZIRWQA-RZPFDVGOSA-N 50163635 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[4-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL277131 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163635&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11398022 104049618 CHEMBL277131 ZINC13613372 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115124 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ncc4c3)C2)cc1 InChI=1S/C27H34FN5O/c28-23-9-7-19(8-10-23)14-20-4-3-13-33(17-20)18-21-5-1-2-6-25(21)31-27(34)30-24-11-12-26-22(15-24)16-29-32-26/h7-12,15-16,20-21,25H,1-6,13-14,17-18H2,(H,29,32)(H2,30,31,34)/t20-,21-,25+/m0/s1 MLPROCBAZKTJHS-STWLZBDKSA-N 50410322 CHEMBL2113077 C-C chemokine receptor type 3 Homo sapiens 0.300000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410322&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11488078 163359346 CHEMBL2113077 ZINC13613319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115126 Fc1ccc(CC2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ccc4c3)C2)cc1 InChI=1S/C28H35FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-14,17,21,23,27,30H,1-6,15-16,18-19H2,(H2,31,32,34)/t21?,23-,27+/m0/s1 YHFFIZVSOADVRF-NPNLJVTBSA-N 50163641 1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indol-5-yl)-urea::CHEMBL195348 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163641&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401328 104049624 CHEMBL195348 ZINC28523574 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115128 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ccc4c3)C2)cc1 InChI=1S/C28H35FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-14,17,21,23,27,30H,1-6,15-16,18-19H2,(H2,31,32,34)/t21-,23-,27+/m0/s1 YHFFIZVSOADVRF-JEYPMZLKSA-N 50410314 CHEMBL2113074 C-C chemokine receptor type 3 Homo sapiens 0.400000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410314&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11328714 163359338 CHEMBL2113074 ZINC13613312 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115129 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ccc4c3)C2)cc1 InChI=1S/C28H35FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-14,17,21,23,27,30H,1-6,15-16,18-19H2,(H2,31,32,34)/t21-,23-,27+/m0/s1 YHFFIZVSOADVRF-JEYPMZLKSA-N 50410314 CHEMBL2113074 C-C chemokine receptor type 3 Homo sapiens 0.016000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410314&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11328714 163359338 CHEMBL2113074 ZINC13613312 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115130 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)NC3CC=C(C(=C3)C#N)n3cccn3)C2)cc1 InChI=1S/C30H37FN6O/c31-26-10-8-22(9-11-26)17-23-5-3-15-36(20-23)21-24-6-1-2-7-28(24)35-30(38)34-27-12-13-29(25(18-27)19-32)37-16-4-14-33-37/h4,8-11,13-14,16,18,23-24,27-28H,1-3,5-7,12,15,17,20-21H2,(H2,34,35,38)/t23-,24-,27?,28+/m0/s1 QPBTXFXXYZMNDD-KYTFRPSZSA-N 50163644 1-(3-Cyano-4-pyrazol-1-yl-cyclohexa-2,4-dienyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL373347 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163644&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401123 104049627 CHEMBL373347 ZINC36352005 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115132 COc1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H36FN3O2/c1-33-26-11-5-4-10-25(26)30-27(32)29-24-9-3-2-8-22(24)19-31-16-6-7-21(18-31)17-20-12-14-23(28)15-13-20/h4-5,10-15,21-22,24H,2-3,6-9,16-19H2,1H3,(H2,29,30,32)/t21-,22-,24+/m0/s1 UKGNFGQNYLRGJL-WPFOTENUSA-N 50163651 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-methoxy-phenyl)-urea::CHEMBL175634 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163651&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11363005 104049634 CHEMBL175634 ZINC13613259 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115133 COc1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C27H37N3O2/c1-32-25-12-7-11-24(19-25)28-27(31)29-26-13-6-5-10-23(26)20-30-16-14-22(15-17-30)18-21-8-3-2-4-9-21/h2-4,7-9,11-12,19,22-23,26H,5-6,10,13-18,20H2,1H3,(H2,28,29,31) FSIZZJSQRKUBMT-UHFFFAOYSA-N 50163672 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-cyclohexyl]-3-(3-methoxy-phenyl)-urea::CHEMBL366654 C-C chemokine receptor type 3 Homo sapiens 423 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163672&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9845853 104049655 CHEMBL366654 ZINC28111808 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115134 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4CNNc4c3)C2)cc1 InChI=1S/C27H36FN5O/c28-23-10-7-19(8-11-23)14-20-4-3-13-33(17-20)18-22-5-1-2-6-25(22)31-27(34)30-24-12-9-21-16-29-32-26(21)15-24/h7-12,15,20,22,25,29,32H,1-6,13-14,16-18H2,(H2,30,31,34)/t20-,22-,25+/m0/s1 IWLSFGNCEVXJQV-UWDQQESISA-N 50163662 1-(3a,7a-Dihydro-1H-indazol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL191604 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163662&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936717 104049645 CHEMBL191604 ZINC28520637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115135 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C30H38FN3O3/c1-20(35)25-15-26(21(2)36)17-28(16-25)32-30(37)33-29-8-4-3-7-24(29)19-34-13-5-6-23(18-34)14-22-9-11-27(31)12-10-22/h9-12,15-17,23-24,29H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,37)/t23-,24-,29+/m0/s1 XNECWHFEDUTGHE-NDIVSWGXSA-N 50163650 1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193575 C-C chemokine receptor type 3 Homo sapiens 0.007000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163650&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11409583 104049633 CHEMBL193575 ZINC13613303 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115136 Fc1ccc(CC2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ncc4c3)C2)cc1 InChI=1S/C27H34FN5O/c28-23-9-7-19(8-10-23)14-20-4-3-13-33(17-20)18-21-5-1-2-6-25(21)31-27(34)30-24-11-12-26-22(15-24)16-29-32-26/h7-12,15-16,20-21,25H,1-6,13-14,17-18H2,(H,29,32)(H2,30,31,34)/t20?,21-,25+/m0/s1 MLPROCBAZKTJHS-FWDVVIQXSA-N 50163659 1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indazol-5-yl)-urea::CHEMBL363373 C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163659&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401561 104049642 CHEMBL363373 ZINC28523389 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115137 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m0/s1 FDDSQKZQCHXOJV-FQEVSTJZSA-N 50142448 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea::1-(3-Acetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46905 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290039 104031829 CHEMBL46905 ZINC13613375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115138 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4CNNc4c3)C2)cc1 InChI=1S/C27H36FN5O/c28-23-10-7-19(8-11-23)14-20-4-3-13-33(17-20)18-22-5-1-2-6-25(22)31-27(34)30-24-12-9-21-16-29-32-26(21)15-24/h7-12,15,20,22,25,29,32H,1-6,13-14,16-18H2,(H2,30,31,34)/t20-,22-,25+/m0/s1 IWLSFGNCEVXJQV-UWDQQESISA-N 50163662 1-(3a,7a-Dihydro-1H-indazol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL191604 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163662&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936717 104049645 CHEMBL191604 ZINC28520637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50115139 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.010000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50119541 [I-].CC[N+]1(C\C2=C\CCCCCC2)CC[C@@H](CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2.HI/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29;/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3;1H/b21-8+;/t24-,34?; FOAFBMYSXIGAOX-CJCAHDPRSA-N 50098624 1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::CHEMBL34626 C-C chemokine receptor type 3 Homo sapiens 6.1 ChEMBL 10.1021/jm0004244 10.7270/Q2G73D0G 11311066 Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098624&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918496 103995616 CHEMBL34626 ZINC13862637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50127007 COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1 NIBJOLRGYNXOPG-QPPBQGQZSA-N 50161436 CHEMBL178438::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 394 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161436&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389675 104047742 CHEMBL178438 ZINC28132125 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50127009 C[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O/c1-19-18-33(12-8-21(19)15-20-4-6-25(29)26(30)16-20)24-9-13-32(14-10-24)28(34)23-5-7-27-22(17-23)3-2-11-31-27/h2-7,11,16-17,19,21,24H,8-10,12-15,18H2,1H3/t19-,21-/m1/s1 GIMAFLOOKFRGCY-TZIWHRDSSA-N 50161415 CHEMBL181460::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 14.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161415&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389688 104047721 CHEMBL181460 ZINC28134725 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50127010 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(12-8-21(27)15-19-4-6-24(29)25(30)16-19)23-9-13-32(14-10-23)28(34)22-5-7-26-20(17-22)3-2-11-31-26/h2-7,11,16-17,21,23,27H,8-10,12-15,18H2,1H3/t21-,27-/m1/s1 OTRJGARPBIJRKG-JIPXPUAJSA-N 50161419 CHEMBL178818::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 7.70 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161419&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11477767 104047725 CHEMBL178818 ZINC28123566 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50127011 OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1 BKSRLDUBSLBPQQ-OFNKIYASSA-N 50161407 CHEMBL178447::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-hydroxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 50.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161407&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11466397 104047713 CHEMBL178447 ZINC28130372 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141455 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.010000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141458 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141459 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.034000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141462 CC(=O)c1sc(NC(=O)N[C@@H]2CS(=O)(=O)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C24H31FN4O4S2/c1-15-22(16(2)30)34-24(26-15)28-23(31)27-21-14-35(32,33)13-19(21)12-29-9-3-4-18(11-29)10-17-5-7-20(25)8-6-17/h5-8,18-19,21H,3-4,9-14H2,1-2H3,(H2,26,27,28,31)/t18-,19+,21+/m0/s1 IRBQOVMCXICGDZ-QKNQBKEWSA-N 50209999 1-(5-acetyl-4-methyl-thiazol-2-yl)-3-{(3S,4S)-4-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl}-urea::CHEMBL249057 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209999&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445854 104086645 CHEMBL249057 ZINC28975225 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141463 CC(=O)c1sc(NC(=O)N[C@@H]2CCNC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H34FN5O2S/c1-16-23(17(2)32)34-25(28-16)30-24(33)29-22-9-10-27-13-20(22)15-31-11-3-4-19(14-31)12-18-5-7-21(26)8-6-18/h5-8,19-20,22,27H,3-4,9-15H2,1-2H3,(H2,28,29,30,33)/t19-,20-,22+/m0/s1 YIHKVKMNPOHFTQ-JAXLGGSGSA-N 50209989 1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL250056 C-C chemokine receptor type 3 Homo sapiens 0.100000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209989&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445845 104086635 CHEMBL250056 ZINC28975173 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141464 CC(=O)c1sc(NC(=O)N[C@@H]2CNCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H34FN5O2S/c1-16-23(17(2)32)34-25(28-16)30-24(33)29-22-13-27-10-9-20(22)15-31-11-3-4-19(14-31)12-18-5-7-21(26)8-6-18/h5-8,19-20,22,27H,3-4,9-15H2,1-2H3,(H2,28,29,30,33)/t19-,20-,22+/m0/s1 MYZPVKYKKLUOPV-JAXLGGSGSA-N 50209972 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251079 C-C chemokine receptor type 3 Homo sapiens 0.075000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209972&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445847 104086618 CHEMBL251079 ZINC28975182 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141465 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 0.030000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141466 CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-16-33(19(3)35)12-10-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 ZFRLEPMXXGKKBN-WPFOTENUSA-N 50209974 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249854 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209974&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11953409 104086620 CHEMBL249854 ZINC28975388 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50141467 CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-16-33(19(3)35)12-10-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 ZFRLEPMXXGKKBN-WPFOTENUSA-N 50209974 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249854 C-C chemokine receptor type 3 Homo sapiens 0.068000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209974&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11953409 104086620 CHEMBL249854 ZINC28975388 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50155205 Oc1ccccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H30FN3O3/c30-24-8-7-22-15-21(5-6-23(22)17-24)18-32-12-11-25(19-32)31-28(35)16-20-9-13-33(14-10-20)29(36)26-3-1-2-4-27(26)34/h1-8,15-17,25,34H,9-14,18-19H2,(H,31,35)/t25-/m1/s1 TVBOHVNCFNQWSW-RUZDIDTESA-N 50297171 CHEMBL551735::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297171&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44512617 104138702 CHEMBL551735 ZINC43024685 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50157374 Cc1ccc(cc1)-c1ccc2CCCC(=Cc2c1)C(=O)Nc1ccc(C[N+](C)(C)C2CCOCC2)cc1 InChI=1S/C33H38N2O2/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32/h7-16,21-22,32H,4-6,17-20,23H2,1-3H3/p+1 XNHZXMPLVSJQFK-UHFFFAOYSA-O 50088301 (E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxamido)benzyl)tetrahydro-2H-pyran-4-aminium chloride::(TAK779)Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium; chloride::CHEMBL41275::CHEMBL64322::Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium; chloride::Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium; chloride(TAK-779)::N-(4-(2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxamido)benzyl)-N,N-dimethyl-tetrahydro-2H-pyran-4-aminium chloride::TAK-779 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1021/jm9906264 10.7270/Q26D5S75 10821717 Shiraishi, M; Aramaki, Y; Seto, M; Imoto, H; Nishikawa, Y; Kanzaki, N; Okamoto, M; Sawada, H; Nishimura, O; Baba, M; Fujino, M Takeda Chemical Industries, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088301&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 183790 103987225 CHEMBL41275CHEMBL64322 ZINC01996578 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50173599 CN(C[C@@H](CCN1CCC2(CS(=O)c3ccccc23)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 InChI=1S/C29H33ClN2O3S2/c1-31(37(34,35)26-10-3-2-4-11-26)21-24(23-8-7-9-25(30)20-23)14-17-32-18-15-29(16-19-32)22-36(33)28-13-6-5-12-27(28)29/h2-13,20,24H,14-19,21-22H2,1H3/t24-,36?/m1/s1 ITHOBZKJMFCARD-LHTANEHXSA-N 50096540 (2S)-2-(3-chlorophenyl)-1-[(N-methyl-N-phenylsulfonyl)amino]-4-[spiro(2,3-dihydrobenzthiophene-3,40-piperidin-10-yl)]butane S-oxide::1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]::1-oxo-1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]::Analogue of 1-[N-(Methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-[4-(substituted)piperidin-1-yl]butane::CHEMBL83338::N-{(S)-2-(3-chloro-phenyl)-4-[4-(1-oxo-spiro-(1-benzothiophene-3,4-piperidin-1-yl)]-butyl}-N-methyl-benzenesulfonamide C-C chemokine receptor type 3 Homo sapiens 10000 ChEMBL 10.1016/s0960-894x(00)00639-9 10.7270/Q2668CFZ 11206474 Finke, PE; Meurer, LC; Oates, B; Mills, SG; MacCoss, M; Malkowitz, L; Springer, MS; Daugherty, BL; Gould, SL; DeMartino, JA; Siciliano, SJ; Carella, A; Carver, G; Holmes, K; Danzeisen, R; Hazuda, D; Kessler, J; Lineberger, J; Miller, M; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096540&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 5481702 103994054 CHEMBL83338 ZINC14128065 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180443 CCOC(=O)[C@H](CCc1ccccc1)NC(=O)c1ccccc1 InChI=1S/C19H21NO3/c1-2-23-19(22)17(14-13-15-9-5-3-6-10-15)20-18(21)16-11-7-4-8-12-16/h3-12,17H,2,13-14H2,1H3,(H,20,21)/t17-/m0/s1 BBGVYTQLRUAOLT-KRWDZBQOSA-N 50100026 (S)-2-Benzoylamino-4-phenyl-butyric acid ethyl ester::CHEMBL32413 C-C chemokine receptor type 3 Homo sapiens 5950 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100026&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9818195 103996842 CHEMBL32413 ZINC29225479 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180444 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)OCc2ccccc2)cc1 InChI=1S/C27H22N2O5/c30-26(24-12-6-10-21-9-4-5-11-23(21)24)28-25(17-19-13-15-22(16-14-19)29(32)33)27(31)34-18-20-7-2-1-3-8-20/h1-16,25H,17-18H2,(H,28,30)/t25-/m0/s1 RSPAJTRUGCCBJD-VWLOTQADSA-N 50100027 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid benzyl ester::CHEMBL32692 C-C chemokine receptor type 3 Homo sapiens 18 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100027&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281789 103996843 CHEMBL32692 ZINC29230220 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180445 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1 InChI=1S/C20H20N2O3/c1-2-25-20(24)18(22-19(23)14-8-4-3-5-9-14)12-15-13-21-17-11-7-6-10-16(15)17/h3-11,13,18,21H,2,12H2,1H3,(H,22,23)/t18-/m0/s1 MBYHQPVAWFROFM-SFHVURJKSA-N 50100028 (S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic acid ethyl ester::CHEMBL33838 C-C chemokine receptor type 3 Homo sapiens 325 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100028&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9927733 103996844 CHEMBL33838 ZINC05460138 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180446 CCOC(=O)[C@@H](NC(=O)c1ccccc1)c1ccccc1 InChI=1S/C17H17NO3/c1-2-21-17(20)15(13-9-5-3-6-10-13)18-16(19)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19)/t15-/m0/s1 GYEKVSOESPZWDI-HNNXBMFYSA-N 50100030 (S)-Benzoylamino-phenyl-acetic acid ethyl ester::CHEMBL32412 C-C chemokine receptor type 3 Homo sapiens >20000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100030&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 7039308 103996846 CHEMBL32412 ZINC03169136 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180447 CCCC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C23H22N2O4/c1-2-6-22(26)21(15-16-11-13-18(14-12-16)25(28)29)24-23(27)20-10-5-8-17-7-3-4-9-19(17)20/h3-5,7-14,21H,2,6,15H2,1H3,(H,24,27)/t21-/m0/s1 STDUJMLSQBQCBD-NRFANRHFSA-N 50100029 CHEMBL32965::Naphthalene-1-carboxylic acid [(S)-1-(4-nitro-benzyl)-2-oxo-pentyl]-amide C-C chemokine receptor type 3 Homo sapiens >33000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100029&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281489 103996845 CHEMBL32965 ZINC29224317 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180448 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1 InChI=1S/C24H29N3O7/c1-2-33-23(31)20(14-16-8-10-18(28)11-9-16)26-22(30)19(12-13-21(25)29)27-24(32)34-15-17-6-4-3-5-7-17/h3-11,19-20,28H,2,12-15H2,1H3,(H2,25,29)(H,26,30)(H,27,32)/t19-,20-/m0/s1 VNLVDIOEQHQDRQ-PMACEKPBSA-N 50100032 (S)-2-((S)-2-Benzyloxycarbonylamino-4-carbamoyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid ethyl ester::CHEMBL32714 C-C chemokine receptor type 3 Homo sapiens >25000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100032&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281349 103996848 CHEMBL32714 ZINC29226011 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180449 CN(C)C(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C22H21N3O4/c1-24(2)22(27)20(14-15-10-12-17(13-11-15)25(28)29)23-21(26)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20H,14H2,1-2H3,(H,23,26)/t20-/m0/s1 OOQSHFDHXRFBML-FQEVSTJZSA-N 50100031 CHEMBL32784::Naphthalene-1-carboxylic acid [(S)-1-dimethylcarbamoyl-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 33000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100031&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281522 103996847 CHEMBL32784 ZINC29229404 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180451 CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1ccc(C)cc1C InChI=1S/C20H22N2O5/c1-4-27-20(24)18(12-15-6-8-16(9-7-15)22(25)26)21-19(23)17-10-5-13(2)11-14(17)3/h5-11,18H,4,12H2,1-3H3,(H,21,23)/t18-/m0/s1 YYJLWRUZBWCURP-SFHVURJKSA-N 50100036 (S)-2-(2,4-Dimethyl-benzoylamino)-3-(4-nitro-phenyl)-propionic acid ethyl ester::CHEMBL290104 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100036&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281521 103996852 CHEMBL290104 ZINC29227989 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180452 CCOC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1 InChI=1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m1/s1 SRLROPAFMUDDRC-MRXNPFEDSA-N 50100035 (R)-2-Benzoylamino-3-(4-hydroxy-phenyl)-propionic acid ethyl ester::CHEMBL33658 C-C chemokine receptor type 3 Homo sapiens >50000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100035&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6999830 103996851 CHEMBL33658 ZINC02036673 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180453 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccn1 InChI=1S/C17H18N2O4/c1-2-23-17(22)15(11-12-6-8-13(20)9-7-12)19-16(21)14-5-3-4-10-18-14/h3-10,15,20H,2,11H2,1H3,(H,19,21)/t15-/m0/s1 KWQAKVQLJFWXIX-HNNXBMFYSA-N 50100034 (S)-3-(4-Hydroxy-phenyl)-2-[(pyridine-2-carbonyl)-amino]-propionic acid ethyl ester::CHEMBL32282 C-C chemokine receptor type 3 Homo sapiens 1700 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100034&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281525 103996850 CHEMBL32282 ZINC29226374 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180454 CCOC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)c1ccccc1 InChI=1S/C18H17I2NO4/c1-2-25-18(24)15(21-17(23)12-6-4-3-5-7-12)10-11-8-13(19)16(22)14(20)9-11/h3-9,15,22H,2,10H2,1H3,(H,21,23)/t15-/m0/s1 LMPGZRBXGQHUBL-HNNXBMFYSA-N 50100033 (S)-2-Benzoylamino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid ethyl ester::CHEMBL290565 C-C chemokine receptor type 3 Homo sapiens 535 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100033&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10257335 103996849 CHEMBL290565 ZINC29228443 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180456 CC(C)OC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C23H22N2O5/c1-15(2)30-23(27)21(14-16-10-12-18(13-11-16)25(28)29)24-22(26)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,15,21H,14H2,1-2H3,(H,24,26)/t21-/m0/s1 BRRSSHDHRPOLFQ-NRFANRHFSA-N 50100037 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid isopropyl ester::CHEMBL33589 C-C chemokine receptor type 3 Homo sapiens 21 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100037&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281791 103996853 CHEMBL33589 ZINC29229101 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180457 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1 InChI=1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m0/s1 SRLROPAFMUDDRC-INIZCTEOSA-N 50100038 (S)-2-Benzoylamino-3-(4-hydroxy-phenyl)-propionic acid ethyl ester::CHEMBL33242 C-C chemokine receptor type 3 Homo sapiens 383 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100038&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 77033 103996854 CHEMBL33242 ZINC01701869 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180458 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1 InChI=1S/C18H19NO3/c1-2-22-18(21)16(13-14-9-5-3-6-10-14)19-17(20)15-11-7-4-8-12-15/h3-12,16H,2,13H2,1H3,(H,19,20)/t16-/m0/s1 WTVXOKSBXDTJEM-INIZCTEOSA-N 50100040 (S)-2-Benzoylamino-3-phenyl-propionic acid ethyl ester::CHEMBL33693 C-C chemokine receptor type 3 Homo sapiens 190 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100040&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 209394 103996856 CHEMBL33693 ZINC03089782 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180459 CC(C)(C)OC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C24H24N2O5/c1-24(2,3)31-23(28)21(15-16-11-13-18(14-12-16)26(29)30)25-22(27)20-10-6-8-17-7-4-5-9-19(17)20/h4-14,21H,15H2,1-3H3,(H,25,27)/t21-/m0/s1 OEEQJRJGAGSVNX-NRFANRHFSA-N 50100039 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid tert-butyl ester::CHEMBL440844 C-C chemokine receptor type 3 Homo sapiens 57 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100039&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281790 103996855 CHEMBL440844 ZINC29226825 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180460 CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1ccccc1 InChI=1S/C18H18N2O5/c1-2-25-18(22)16(19-17(21)14-6-4-3-5-7-14)12-13-8-10-15(11-9-13)20(23)24/h3-11,16H,2,12H2,1H3,(H,19,21)/t16-/m0/s1 BEZXGSZPWXRHIN-INIZCTEOSA-N 50100041 (S)-2-Benzoylamino-3-(4-nitro-phenyl)-propionic acid ethyl ester::CHEMBL284954 C-C chemokine receptor type 3 Homo sapiens 49 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100041&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9840971 103996857 CHEMBL284954 ZINC29225159 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180461 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 InChI=1S/C19H21NO4/c1-2-24-19(23)17(12-15-8-10-16(21)11-9-15)20-18(22)13-14-6-4-3-5-7-14/h3-11,17,21H,2,12-13H2,1H3,(H,20,22)/t17-/m0/s1 CUKZFXPYGLVPOB-KRWDZBQOSA-N 50100042 (S)-3-(4-Hydroxy-phenyl)-2-phenylacetylamino-propionic acid ethyl ester::CHEMBL33290 C-C chemokine receptor type 3 Homo sapiens 2600 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100042&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11001953 103996858 CHEMBL33290 ZINC29221604 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180463 CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C22H20N2O5/c1-2-29-22(26)20(14-15-10-12-17(13-11-15)24(27)28)23-21(25)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20H,2,14H2,1H3,(H,23,25)/t20-/m0/s1 HIDAYZUFDIMAHT-FQEVSTJZSA-N 50100044 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid ethyl ester::CHEMBL32210 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100044&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9800669 103996860 CHEMBL32210 ZINC29224439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180465 CCOC(=O)[C@H](C)NC(=O)c1ccccc1 InChI=1S/C12H15NO3/c1-3-16-12(15)9(2)13-11(14)10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,14)/t9-/m0/s1 OJNMULJHNFYKCF-VIFPVBQESA-N 50100043 (S)-2-Benzoylamino-propionic acid ethyl ester::CHEMBL32878 C-C chemokine receptor type 3 Homo sapiens 9000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100043&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6995527 103996859 CHEMBL32878 ZINC01758569 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180466 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 InChI=1S/C28H30N2O6/c1-2-35-27(33)25(18-21-13-15-23(31)16-14-21)29-26(32)24(17-20-9-5-3-6-10-20)30-28(34)36-19-22-11-7-4-8-12-22/h3-16,24-25,31H,2,17-19H2,1H3,(H,29,32)(H,30,34)/t24-,25-/m0/s1 MXDCALVQBWORSC-DQEYMECFSA-N 50100045 (S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-3-(4-hydroxy-phenyl)-propionic acid ethyl ester::CHEMBL32468 C-C chemokine receptor type 3 Homo sapiens 6250 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100045&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 7072714 103996861 CHEMBL32468 ZINC04015565 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180468 C[C@H](NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)N(C)c1ccccc1 InChI=1S/C30H28N4O5/c1-20(30(37)33(2)23-11-4-3-5-12-23)31-29(36)27(19-21-15-17-24(18-16-21)34(38)39)32-28(35)26-14-8-10-22-9-6-7-13-25(22)26/h3-18,20,27H,19H2,1-2H3,(H,31,36)(H,32,35)/t20-,27-/m0/s1 UKKZQBRJAFGYNQ-DCFHFQCYSA-N 50100047 CHEMBL432088::Naphthalene-1-carboxylic acid [(S)-1-[(S)-1-(methyl-phenyl-carbamoyl)-ethylcarbamoyl]-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100047&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281794 103996863 CHEMBL432088 ZINC01549273 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180469 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2cnco2)cc1 InChI=1S/C22H17N3O4/c26-22(19-7-3-5-16-4-1-2-6-18(16)19)24-20(21-13-23-14-29-21)12-15-8-10-17(11-9-15)25(27)28/h1-11,13-14,20H,12H2,(H,24,26)/t20-/m0/s1 POHIAJHKHVUSEF-FQEVSTJZSA-N 50100046 CHEMBL288554::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-oxazol-5-yl-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 22500 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100046&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281943 103996862 CHEMBL288554 ZINC29236853 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180470 COc1ccccc1NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(cc1)C#N)NC(=O)c1cccc2ccccc12 InChI=1S/C31H28N4O4/c1-20(29(36)34-26-12-5-6-13-28(26)39-2)33-31(38)27(18-21-14-16-22(19-32)17-15-21)35-30(37)25-11-7-9-23-8-3-4-10-24(23)25/h3-17,20,27H,18H2,1-2H3,(H,33,38)(H,34,36)(H,35,37)/t20-,27-/m0/s1 PMBWQSDHUMGYMV-DCFHFQCYSA-N 50100049 CHEMBL32852::Naphthalene-1-carboxylic acid {(S)-2-(4-cyano-phenyl)-1-[(S)-1-(2-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 125 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100049&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282048 103996865 CHEMBL32852 ZINC29233459 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180471 C[C@H](N(C)C(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)Nc1ccccc1 InChI=1S/C30H28N4O5/c1-20(28(35)31-23-11-4-3-5-12-23)33(2)30(37)27(19-21-15-17-24(18-16-21)34(38)39)32-29(36)26-14-8-10-22-9-6-7-13-25(22)26/h3-18,20,27H,19H2,1-2H3,(H,31,35)(H,32,36)/t20-,27-/m0/s1 HMTYUXSBGQACHJ-DCFHFQCYSA-N 50100050 CHEMBL33534::Naphthalene-1-carboxylic acid [(S)-1-[methyl-((S)-1-phenylcarbamoyl-ethyl)-carbamoyl]-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 65 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100050&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281775 103996866 CHEMBL33534 ZINC01547910 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180472 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180473 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2nc(cs2)C(=O)Nc2ccccc2)cc1 InChI=1S/C29H22N4O4S/c34-27(24-12-6-8-20-7-4-5-11-23(20)24)31-25(17-19-13-15-22(16-14-19)33(36)37)29-32-26(18-38-29)28(35)30-21-9-2-1-3-10-21/h1-16,18,25H,17H2,(H,30,35)(H,31,34)/t25-/m0/s1 FLKCYAYSWJBUPP-VWLOTQADSA-N 50100051 2-[(S)-1-[(Naphthalene-1-carbonyl)-amino]-2-(4-nitro-phenyl)-ethyl]-thiazole-4-carboxylic acid phenylamide::CHEMBL32191 C-C chemokine receptor type 3 Homo sapiens 7700 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100051&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281872 103996867 CHEMBL32191 ZINC29227866 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180474 CCOC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H25N3O6/c1-3-34-25(31)16(2)26-24(30)22(15-17-11-13-19(14-12-17)28(32)33)27-23(29)21-10-6-8-18-7-4-5-9-20(18)21/h4-14,16,22H,3,15H2,1-2H3,(H,26,30)(H,27,29)/t16-,22+/m1/s1 MGVGRKCWAMZYNI-ZHRRBRCNSA-N 50100052 (R)-2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-propionic acid ethyl ester::CHEMBL32334 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100052&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281859 103996868 CHEMBL32334 ZINC01547908 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180475 CCOC(=O)C1COC(=N1)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H23N3O6/c1-2-33-25(30)22-15-34-24(27-22)21(14-16-10-12-18(13-11-16)28(31)32)26-23(29)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,21-22H,2,14-15H2,1H3,(H,26,29)/t21-,22?/m0/s1 SAGOLQJOHHFBJI-HMTLIYDFSA-N 50100054 2-[(S)-1-[(Naphthalene-1-carbonyl)-amino]-2-(4-nitro-phenyl)-ethyl]-4,5-dihydro-oxazole-4-carboxylic acid ethyl ester::CHEMBL32850 C-C chemokine receptor type 3 Homo sapiens 213 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100054&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282030 103996870 CHEMBL32850 ZINC29232940 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180476 CCNC(=O)C(C)NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H26N4O5/c1-3-26-23(30)16(2)27-25(32)22(15-17-11-13-19(14-12-17)29(33)34)28-24(31)21-10-6-8-18-7-4-5-9-20(18)21/h4-14,16,22H,3,15H2,1-2H3,(H,26,30)(H,27,32)(H,28,31)/t16?,22-/m0/s1 GFQBDYBEQZBMLE-XLDIYJRPSA-N 50100055 CHEMBL32895::Naphthalene-1-carboxylic acid [(S)-1-(1-ethylcarbamoyl-ethylcarbamoyl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 666 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100055&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281686 103996871 CHEMBL32895 ZINC29229144 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180477 C[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c1cccc2ccccc12)C(=O)Nc1ccccc1 InChI=1S/C29H26ClN3O3/c1-19(27(34)32-23-10-3-2-4-11-23)31-29(36)26(18-20-14-16-22(30)17-15-20)33-28(35)25-13-7-9-21-8-5-6-12-24(21)25/h2-17,19,26H,18H2,1H3,(H,31,36)(H,32,34)(H,33,35)/t19-,26-/m0/s1 SIXCSUPVBMXKDU-SIBVEZHUSA-N 50100048 CHEMBL418588::Naphthalene-1-carboxylic acid [(S)-2-(4-chloro-phenyl)-1-((S)-1-phenylcarbamoyl-ethylcarbamoyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100048&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9957612 103996864 CHEMBL418588 ZINC01547909 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180479 CC(NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)NCc1ccccc1 InChI=1S/C30H28N4O5/c1-20(28(35)31-19-22-8-3-2-4-9-22)32-30(37)27(18-21-14-16-24(17-15-21)34(38)39)33-29(36)26-13-7-11-23-10-5-6-12-25(23)26/h2-17,20,27H,18-19H2,1H3,(H,31,35)(H,32,37)(H,33,36)/t20?,27-/m0/s1 MTMSCELVTMFEIT-OHMHCFLMSA-N 50100057 CHEMBL33537::Naphthalene-1-carboxylic acid [(S)-1-(1-benzylcarbamoyl-ethylcarbamoyl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 300 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100057&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281667 103996873 CHEMBL33537 ZINC29227290 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180480 C[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c1ccc(C)cc1C)C(=O)Nc1ccc(Cl)cc1 InChI=1S/C27H27Cl2N3O3/c1-16-4-13-23(17(2)14-16)26(34)32-24(15-19-5-7-20(28)8-6-19)27(35)30-18(3)25(33)31-22-11-9-21(29)10-12-22/h4-14,18,24H,15H2,1-3H3,(H,30,35)(H,31,33)(H,32,34)/t18-,24-/m0/s1 WHCHMYUXPNEYPT-UUOWRZLLSA-N 50100058 CHEMBL284531::N-{(S)-2-(4-Chloro-phenyl)-1-[(S)-1-(4-chloro-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-2,4-dimethyl-benzamide C-C chemokine receptor type 3 Homo sapiens 45 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100058&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281852 103996874 CHEMBL284531 ZINC29228811 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180482 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C2=NCCO2)cc1 InChI=1S/C22H19N3O4/c26-21(19-7-3-5-16-4-1-2-6-18(16)19)24-20(22-23-12-13-29-22)14-15-8-10-17(11-9-15)25(27)28/h1-11,20H,12-14H2,(H,24,26)/t20-/m0/s1 RCGFTRXGKZXOOI-FQEVSTJZSA-N 50100053 CHEMBL32493::Naphthalene-1-carboxylic acid [(S)-1-(4,5-dihydro-oxazol-2-yl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 563 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100053&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9952288 103996869 CHEMBL32493 ZINC00602395 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180483 CC(NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)N1CCCC1 InChI=1S/C27H28N4O5/c1-18(27(34)30-15-4-5-16-30)28-26(33)24(17-19-11-13-21(14-12-19)31(35)36)29-25(32)23-10-6-8-20-7-2-3-9-22(20)23/h2-3,6-14,18,24H,4-5,15-17H2,1H3,(H,28,33)(H,29,32)/t18?,24-/m0/s1 KPCYEEKJNZWMNU-LUTIACGYSA-N 50100059 CHEMBL34839::Naphthalene-1-carboxylic acid [(S)-1-(1-methyl-2-oxo-2-pyrrolidin-1-yl-ethylcarbamoyl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 1125 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100059&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282031 103996875 CHEMBL34839 ZINC29232954 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180484 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2ncco2)cc1 InChI=1S/C22H17N3O4/c26-21(19-7-3-5-16-4-1-2-6-18(16)19)24-20(22-23-12-13-29-22)14-15-8-10-17(11-9-15)25(27)28/h1-13,20H,14H2,(H,24,26)/t20-/m0/s1 ZPRQKFILZIQITE-FQEVSTJZSA-N 50100061 CHEMBL33476::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-oxazol-2-yl-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens >33000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100061&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282379 103996877 CHEMBL33476 ZINC29231917 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180485 CCOC(=O)c1coc(n1)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H21N3O6/c1-2-33-25(30)22-15-34-24(27-22)21(14-16-10-12-18(13-11-16)28(31)32)26-23(29)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,15,21H,2,14H2,1H3,(H,26,29)/t21-/m0/s1 MPFYIOVBNROYFL-NRFANRHFSA-N 50100060 2-[(S)-1-[(Naphthalene-1-carbonyl)-amino]-2-(4-nitro-phenyl)-ethyl]-oxazole-4-carboxylic acid ethyl ester::CHEMBL35900 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100060&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281999 103996876 CHEMBL35900 ZINC29235504 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180486 C[C@H](NC(=O)[C@H](Cc1ccncc1)NC(=O)c1cccc2ccccc12)C(=O)Nc1ccc(cc1)-c1ccccc1 InChI=1S/C34H30N4O3/c1-23(32(39)37-28-16-14-26(15-17-28)25-8-3-2-4-9-25)36-34(41)31(22-24-18-20-35-21-19-24)38-33(40)30-13-7-11-27-10-5-6-12-29(27)30/h2-21,23,31H,22H2,1H3,(H,36,41)(H,37,39)(H,38,40)/t23-,31-/m0/s1 ZYHPVPNIYWSSDU-FWUCURJTSA-N 50100062 CHEMBL284313::Naphthalene-1-carboxylic acid {(S)-1-[(S)-1-(biphenyl-4-ylcarbamoyl)-ethylcarbamoyl]-2-pyridin-4-yl-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100062&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281987 103996878 CHEMBL284313 ZINC29236264 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180487 CCNC(=O)c1csc(n1)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H22N4O4S/c1-2-26-24(31)22-15-34-25(28-22)21(14-16-10-12-18(13-11-16)29(32)33)27-23(30)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,15,21H,2,14H2,1H3,(H,26,31)(H,27,30)/t21-/m0/s1 BAXNZFTYFFRSMD-NRFANRHFSA-N 50100064 2-[(S)-1-[(Naphthalene-1-carbonyl)-amino]-2-(4-nitro-phenyl)-ethyl]-thiazole-4-carboxylic acid ethylamide::CHEMBL36473 C-C chemokine receptor type 3 Homo sapiens 18000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100064&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281891 103996880 CHEMBL36473 ZINC29233059 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180488 COc1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)N[C@@H](C)C(=O)Nc2ccccc2OC)cc1 InChI=1S/C31H31N3O5/c1-20(29(35)33-26-13-6-7-14-28(26)39-3)32-31(37)27(19-21-15-17-23(38-2)18-16-21)34-30(36)25-12-8-10-22-9-4-5-11-24(22)25/h4-18,20,27H,19H2,1-3H3,(H,32,37)(H,33,35)(H,34,36)/t20-,27-/m0/s1 NAHWEPZIYZZSOH-DCFHFQCYSA-N 50100065 CHEMBL36195::Naphthalene-1-carboxylic acid {(S)-2-(4-methoxy-phenyl)-1-[(S)-1-(2-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 15 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100065&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282006 103996881 CHEMBL36195 ZINC03975604 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180489 C[C@H](NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)Nc1ccccc1 InChI=1S/C29H26N4O5/c1-19(27(34)31-22-10-3-2-4-11-22)30-29(36)26(18-20-14-16-23(17-15-20)33(37)38)32-28(35)25-13-7-9-21-8-5-6-12-24(21)25/h2-17,19,26H,18H2,1H3,(H,30,36)(H,31,34)(H,32,35)/t19-,26-/m0/s1 UMZYUNIVMXENNH-SIBVEZHUSA-N 50100066 CHEMBL32224::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-((S)-1-phenylcarbamoyl-ethylcarbamoyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 190 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100066&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281612 103996882 CHEMBL32224 ZINC01548900 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180490 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)NCC(=O)Nc2ccccc2)cc1 InChI=1S/C28H24N4O5/c33-26(30-21-9-2-1-3-10-21)18-29-28(35)25(17-19-13-15-22(16-14-19)32(36)37)31-27(34)24-12-6-8-20-7-4-5-11-23(20)24/h1-16,25H,17-18H2,(H,29,35)(H,30,33)(H,31,34)/t25-/m0/s1 JKHBZFDAGCVQJB-VWLOTQADSA-N 50100063 CHEMBL32806::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-(phenylcarbamoylmethyl-carbamoyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 400 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100063&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281706 103996879 CHEMBL32806 ZINC01549271 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180491 COc1ccc(NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(cc2)C#N)NC(=O)c2cccc3ccccc23)cc1 InChI=1S/C31H28N4O4/c1-20(29(36)34-24-14-16-25(39-2)17-15-24)33-31(38)28(18-21-10-12-22(19-32)13-11-21)35-30(37)27-9-5-7-23-6-3-4-8-26(23)27/h3-17,20,28H,18H2,1-2H3,(H,33,38)(H,34,36)(H,35,37)/t20-,28-/m0/s1 JLXZDVOWGKXVIG-MMTVBGGISA-N 50100067 CHEMBL418041::Naphthalene-1-carboxylic acid {(S)-2-(4-cyano-phenyl)-1-[(S)-1-(4-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 90 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100067&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282047 103996883 CHEMBL418041 ZINC29233455 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180492 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2nc(cs2)C(=O)N2CCc3ccccc3C2)cc1 InChI=1S/C32H26N4O4S/c37-30(27-11-5-9-23-7-3-4-10-26(23)27)33-28(18-21-12-14-25(15-13-21)36(39)40)31-34-29(20-41-31)32(38)35-17-16-22-6-1-2-8-24(22)19-35/h1-15,20,28H,16-19H2,(H,33,37)/t28-/m0/s1 INTSHLCZQVTJSM-NDEPHWFRSA-N 50100069 CHEMBL287320::Naphthalene-1-carboxylic acid [(S)-1-[4-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-thiazol-2-yl]-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 12500 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100069&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282385 103996885 CHEMBL287320 ZINC29229666 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180493 COc1ccc(NC(=O)[C@H](C)NC(=O)[C@H](CC2CCCCC2)NC(=O)c2cccc3ccccc23)cc1 InChI=1S/C30H35N3O4/c1-20(28(34)32-23-15-17-24(37-2)18-16-23)31-30(36)27(19-21-9-4-3-5-10-21)33-29(35)26-14-8-12-22-11-6-7-13-25(22)26/h6-8,11-18,20-21,27H,3-5,9-10,19H2,1-2H3,(H,31,36)(H,32,34)(H,33,35)/t20-,27-/m0/s1 XDNLNQRPYFXQBU-DCFHFQCYSA-N 50100068 CHEMBL33708::Naphthalene-1-carboxylic acid {(S)-2-cyclohexyl-1-[(S)-1-(4-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 700 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100068&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281774 103996884 CHEMBL33708 ZINC29228235 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180494 C[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c1cccc2ccccc12)C(=O)Nc1cccnc1 InChI=1S/C28H25ClN4O3/c1-18(26(34)32-22-8-5-15-30-17-22)31-28(36)25(16-19-11-13-21(29)14-12-19)33-27(35)24-10-4-7-20-6-2-3-9-23(20)24/h2-15,17-18,25H,16H2,1H3,(H,31,36)(H,32,34)(H,33,35)/t18-,25-/m0/s1 ITBFOZWYADNNQO-BVZFJXPGSA-N 50100073 CHEMBL32451::Naphthalene-1-carboxylic acid {(S)-2-(4-chloro-phenyl)-1-[(S)-1-(pyridin-3-ylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 27 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100073&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281668 103996889 CHEMBL32451 ZINC01549274 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180495 CCOC(=O)c1csc(n1)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H21N3O5S/c1-2-33-25(30)22-15-34-24(27-22)21(14-16-10-12-18(13-11-16)28(31)32)26-23(29)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,15,21H,2,14H2,1H3,(H,26,29)/t21-/m0/s1 NDASNSDAFLKKKH-NRFANRHFSA-N 50100072 2-[(S)-1-[(Naphthalene-1-carbonyl)-amino]-2-(4-nitro-phenyl)-ethyl]-thiazole-4-carboxylic acid ethyl ester::CHEMBL35217 C-C chemokine receptor type 3 Homo sapiens 663 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100072&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281951 103996888 CHEMBL35217 ZINC29233752 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180496 C[C@H](NC(=O)[C@H](Cc1cscn1)NC(=O)c1cccc2ccccc12)C(=O)Nc1ccc(Cl)cc1 InChI=1S/C26H23ClN4O3S/c1-16(24(32)30-19-11-9-18(27)10-12-19)29-26(34)23(13-20-14-35-15-28-20)31-25(33)22-8-4-6-17-5-2-3-7-21(17)22/h2-12,14-16,23H,13H2,1H3,(H,29,34)(H,30,32)(H,31,33)/t16-,23-/m0/s1 TZBZUOFATREDMN-HJPURHCSSA-N 50100070 CHEMBL33144::Naphthalene-1-carboxylic acid {(S)-1-[(S)-1-(4-chloro-phenylcarbamoyl)-ethylcarbamoyl]-2-thiazol-4-yl-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 800 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100070&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281754 103996886 CHEMBL33144 ZINC29229276 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180497 COc1ccc(NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)c2cccc3ccccc23)cc1 InChI=1S/C30H28ClN3O4/c1-19(28(35)33-23-14-16-24(38-2)17-15-23)32-30(37)27(18-20-10-12-22(31)13-11-20)34-29(36)26-9-5-7-21-6-3-4-8-25(21)26/h3-17,19,27H,18H2,1-2H3,(H,32,37)(H,33,35)(H,34,36)/t19-,27-/m0/s1 NGYDPNWYWQOWLJ-PPHZAIPVSA-N 50100077 CHEMBL35896::Naphthalene-1-carboxylic acid {(S)-2-(4-chloro-phenyl)-1-[(S)-1-(4-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 45 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100077&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281944 103996893 CHEMBL35896 ZINC29236463 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180498 COc1ccc(NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccncc2)NC(=O)c2cccc3ccccc23)cc1 InChI=1S/C29H28N4O4/c1-19(27(34)32-22-10-12-23(37-2)13-11-22)31-29(36)26(18-20-14-16-30-17-15-20)33-28(35)25-9-5-7-21-6-3-4-8-24(21)25/h3-17,19,26H,18H2,1-2H3,(H,31,36)(H,32,34)(H,33,35)/t19-,26-/m0/s1 MDUTWDZUHDFPAV-SIBVEZHUSA-N 50100075 CHEMBL32320::Naphthalene-1-carboxylic acid {(S)-1-[(S)-1-(4-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-2-pyridin-4-yl-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens >1220 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100075&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281915 103996891 CHEMBL32320 ZINC29234100 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180499 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2nnco2)cc1 InChI=1S/C21H16N4O4/c26-20(18-7-3-5-15-4-1-2-6-17(15)18)23-19(21-24-22-13-29-21)12-14-8-10-16(11-9-14)25(27)28/h1-11,13,19H,12H2,(H,23,26)/t19-/m0/s1 RKKOSWWJWAYKGN-IBGZPJMESA-N 50100071 CHEMBL33131::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-[1,3,4]oxadiazol-2-yl-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens >33000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100071&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281916 103996887 CHEMBL33131 ZINC29234107 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180500 CCOC(=O)C(=C)NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H23N3O6/c1-3-34-25(31)16(2)26-24(30)22(15-17-11-13-19(14-12-17)28(32)33)27-23(29)21-10-6-8-18-7-4-5-9-20(18)21/h4-14,22H,2-3,15H2,1H3,(H,26,30)(H,27,29)/t22-/m0/s1 SGTOEQGRIUVVPV-QFIPXVFZSA-N 50100074 2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-acrylic acid ethyl ester::CHEMBL178019 C-C chemokine receptor type 3 Homo sapiens 350 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100074&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44386406 103996890 CHEMBL178019 ZINC28102168 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180501 COc1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)N[C@@H](C)C(=O)Nc2ccc(cc2)C#N)cc1 InChI=1S/C31H28N4O4/c1-20(29(36)34-24-14-10-22(19-32)11-15-24)33-31(38)28(18-21-12-16-25(39-2)17-13-21)35-30(37)27-9-5-7-23-6-3-4-8-26(23)27/h3-17,20,28H,18H2,1-2H3,(H,33,38)(H,34,36)(H,35,37)/t20-,28-/m0/s1 WVOGSMZUQGZXAT-MMTVBGGISA-N 50100078 CHEMBL36223::Naphthalene-1-carboxylic acid [(S)-1-[(S)-1-(4-cyano-phenylcarbamoyl)-ethylcarbamoyl]-2-(4-methoxy-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 250 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100078&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282005 103996894 CHEMBL36223 ZINC29240590 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180502 C[C@@H](NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12)C(=O)OC(C)(C)C InChI=1S/C27H29N3O6/c1-17(26(33)36-27(2,3)4)28-25(32)23(16-18-12-14-20(15-13-18)30(34)35)29-24(31)22-11-7-9-19-8-5-6-10-21(19)22/h5-15,17,23H,16H2,1-4H3,(H,28,32)(H,29,31)/t17-,23+/m1/s1 XKDINPCOLJVWBD-HXOBKFHXSA-N 50100076 (R)-2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-propionic acid tert-butyl ester::CHEMBL284166 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100076&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281975 103996892 CHEMBL284166 ZINC29231995 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180503 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)c2nccs2)cc1 InChI=1S/C22H17N3O3S/c26-21(19-7-3-5-16-4-1-2-6-18(16)19)24-20(22-23-12-13-29-22)14-15-8-10-17(11-9-15)25(27)28/h1-13,20H,14H2,(H,24,26)/t20-/m0/s1 IFXLSJSHQRUAHB-FQEVSTJZSA-N 50100079 CHEMBL285444::Naphthalene-1-carboxylic acid [(S)-2-(4-nitro-phenyl)-1-thiazol-2-yl-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 32000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100079&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281966 103996895 CHEMBL285444 ZINC29228972 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180504 CCOC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C25H25N3O6/c1-3-34-25(31)16(2)26-24(30)22(15-17-11-13-19(14-12-17)28(32)33)27-23(29)21-10-6-8-18-7-4-5-9-20(18)21/h4-14,16,22H,3,15H2,1-2H3,(H,26,30)(H,27,29)/t16-,22-/m0/s1 MGVGRKCWAMZYNI-AOMKIAJQSA-N 50100082 (S)-2-[(S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionylamino]-propionic acid ethyl ester::CHEMBL35341 C-C chemokine receptor type 3 Homo sapiens 383 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44282280 103996898 CHEMBL35341 ZINC13916375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180505 COc1ccc(NC(=O)[C@H](C)NC(=O)[C@H](Cc2cscn2)NC(=O)c2cccc3ccccc23)cc1 InChI=1S/C27H26N4O4S/c1-17(25(32)30-19-10-12-21(35-2)13-11-19)29-27(34)24(14-20-15-36-16-28-20)31-26(33)23-9-5-7-18-6-3-4-8-22(18)23/h3-13,15-17,24H,14H2,1-2H3,(H,29,34)(H,30,32)(H,31,33)/t17-,24-/m0/s1 OCSMZEPWSVLVAQ-XDHUDOTRSA-N 50100081 CHEMBL284576::Naphthalene-1-carboxylic acid {(S)-1-[(S)-1-(4-methoxy-phenylcarbamoyl)-ethylcarbamoyl]-2-thiazol-4-yl-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281755 103996897 CHEMBL284576 ZINC29227781 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180507 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)N[C@H](C(=O)Nc2ccccc2)c2ccccc2)cc1 InChI=1S/C34H28N4O5/c39-32(29-17-9-13-24-10-7-8-16-28(24)29)36-30(22-23-18-20-27(21-19-23)38(42)43)33(40)37-31(25-11-3-1-4-12-25)34(41)35-26-14-5-2-6-15-26/h1-21,30-31H,22H2,(H,35,41)(H,36,39)(H,37,40)/t30-,31-/m0/s1 NAARJKKDZKRFBW-CONSDPRKSA-N 50100080 CHEMBL32410::Naphthalene-1-carboxylic acid {(S)-2-(4-nitro-phenyl)-1-[((S)-phenyl-phenylcarbamoyl-methyl)-carbamoyl]-ethyl}-amide C-C chemokine receptor type 3 Homo sapiens 116 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100080&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281673 103996896 CHEMBL32410 ZINC29227513 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179200 Clc1ccc(CN2CCC(CC2)NC(=O)CSc2nc3ccccc3s2)cc1 InChI=1S/C21H22ClN3OS2/c22-16-7-5-15(6-8-16)13-25-11-9-17(10-12-25)23-20(26)14-27-21-24-18-3-1-2-4-19(18)28-21/h1-8,17H,9-14H2,(H,23,26) CDBSOQNHMUTLEM-UHFFFAOYSA-N 50099476 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL282285 C-C chemokine receptor type 3 Homo sapiens 79 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099476&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10873705 103996347 CHEMBL282285 ZINC28230897 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179202 O=C(CSc1nc2ccccc2s1)NCC1CCCN(CC2CCCCC2)C1 InChI=1S/C22H31N3OS2/c26-21(16-27-22-24-19-10-4-5-11-20(19)28-22)23-13-18-9-6-12-25(15-18)14-17-7-2-1-3-8-17/h4-5,10-11,17-18H,1-3,6-9,12-16H2,(H,23,26) DSBULHATUKJWAF-UHFFFAOYSA-N 50099478 2-(Benzothiazol-2-ylsulfanyl)-N-(1-cyclohexylmethyl-piperidin-3-ylmethyl)-acetamide::CHEMBL279450 C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099478&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44273640 103996349 CHEMBL279450 ZINC28231211 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179205 Nc1ccc2nc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)sc2c1 InChI=1S/C21H22Cl2N4OS2/c22-16-3-1-13(9-17(16)23)11-27-7-5-15(6-8-27)25-20(28)12-29-21-26-18-4-2-14(24)10-19(18)30-21/h1-4,9-10,15H,5-8,11-12,24H2,(H,25,28) QOHFBKIKGAINLL-UHFFFAOYSA-N 50099482 2-(6-Amino-benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL20921 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9913085 103996353 CHEMBL20921 796 ZINC00602832 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179207 O=C(CSc1nc2ccccc2s1)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H23N3OS2/c25-20(15-26-21-23-18-8-4-5-9-19(18)27-21)22-17-10-12-24(13-11-17)14-16-6-2-1-3-7-16/h1-9,17H,10-15H2,(H,22,25) LHFVURFEDUAKJQ-UHFFFAOYSA-N 50099481 2-(Benzothiazol-2-ylsulfanyl)-N-(1-benzyl-piperidin-4-yl)-acetamide::CHEMBL20539 C-C chemokine receptor type 3 Homo sapiens 750 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099481&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10000888 103996352 CHEMBL20539 ZINC15564548 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179208 Clc1ccc(CN2CCC(CC2)NC(=O)CSc2nc3ccccc3s2)cc1Cl InChI=1S/C21H21Cl2N3OS2/c22-16-6-5-14(11-17(16)23)12-26-9-7-15(8-10-26)24-20(27)13-28-21-25-18-3-1-2-4-19(18)29-21/h1-6,11,15H,7-10,12-13H2,(H,24,27) BFHKONATEMTJLB-UHFFFAOYSA-N 50099480 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL20532 C-C chemokine receptor type 3 Homo sapiens 32 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099480&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11037958 103996351 CHEMBL20532 ZINC28232602 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179209 CCOC(=O)c1ccc2nc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)sc2c1 InChI=1S/C24H25Cl2N3O3S2/c1-2-32-23(31)16-4-6-20-21(12-16)34-24(28-20)33-14-22(30)27-17-7-9-29(10-8-17)13-15-3-5-18(25)19(26)11-15/h3-6,11-12,17H,2,7-10,13-14H2,1H3,(H,27,30) MUBFOUDNGKIFMW-UHFFFAOYSA-N 50099483 2-{[1-(3,4-Dichloro-benzyl)-piperidin-4-ylcarbamoyl]-methylsulfanyl}-benzothiazole-6-carboxylic acid ethyl ester::CHEMBL266181 C-C chemokine receptor type 3 Homo sapiens 48 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099483&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10984360 103996354 CHEMBL266181 ZINC28232598 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179213 [I-].CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2.HI/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29;/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3;1H/b21-8+; FOAFBMYSXIGAOX-LQGGPMKRSA-N 50098643 1-((E)-1-Cyclooct-1-enyl)methyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::CHEMBL277930 C-C chemokine receptor type 3 Homo sapiens 0.580000 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098643&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918496 103995635 CHEMBL277930 ZINC03979252 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179214 O=C(CSc1nc2ccccc2s1)NCC1CCCN(Cc2ccccc2)C1 InChI=1S/C22H25N3OS2/c26-21(16-27-22-24-19-10-4-5-11-20(19)28-22)23-13-18-9-6-12-25(15-18)14-17-7-2-1-3-8-17/h1-5,7-8,10-11,18H,6,9,12-16H2,(H,23,26) HMSUMXAXIIHIJY-UHFFFAOYSA-N 50099475 2-(Benzothiazol-2-ylsulfanyl)-N-(1-benzyl-piperidin-3-ylmethyl)-acetamide::CHEMBL21199 C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099475&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9979012 103996346 CHEMBL21199 ZINC28233467 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179216 CCOc1ccc2nc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)sc2c1 InChI=1S/C23H25Cl2N3O2S2/c1-2-30-17-4-6-20-21(12-17)32-23(27-20)31-14-22(29)26-16-7-9-28(10-8-16)13-15-3-5-18(24)19(25)11-15/h3-6,11-12,16H,2,7-10,13-14H2,1H3,(H,26,29) DMLMULMWAGUVQC-UHFFFAOYSA-N 50099479 CHEMBL21143::N-[1-(3,4-Dichloro-benzyl)-piperidin-4-yl]-2-(6-ethoxy-benzothiazol-2-ylsulfanyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11113940 103996350 CHEMBL21143 ZINC28232576 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50179217 Clc1cccc(CN2CCC(CC2)NC(=O)CSc2nc3ccccc3s2)c1 InChI=1S/C21H22ClN3OS2/c22-16-5-3-4-15(12-16)13-25-10-8-17(9-11-25)23-20(26)14-27-21-24-18-6-1-2-7-19(18)28-21/h1-7,12,17H,8-11,13-14H2,(H,23,26) ZOSLWYPGKZWGQK-UHFFFAOYSA-N 50099477 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3-chloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL20612 C-C chemokine receptor type 3 Homo sapiens 280 ChEMBL 10.1016/s0960-894x(01)00176-7 10.7270/Q22V2FDC 11354381 Naya, A; Kobayashi, K; Ishikawa, M; Ohwaki, K; Saeki, T; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099477&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10928173 103996348 CHEMBL20612 ZINC28235877 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180433 [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)NCc2ccccc2)cc1 InChI=1S/C27H23N3O4/c31-26(24-12-6-10-21-9-4-5-11-23(21)24)29-25(17-19-13-15-22(16-14-19)30(33)34)27(32)28-18-20-7-2-1-3-8-20/h1-16,25H,17-18H2,(H,28,32)(H,29,31)/t25-/m0/s1 VLAZHAYFJDZIQM-VWLOTQADSA-N 50100019 CHEMBL284577::Naphthalene-1-carboxylic acid [(S)-1-benzylcarbamoyl-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens 4000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100019&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281523 103996835 CHEMBL284577 ZINC29229407 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180434 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1 InChI=1S/C22H26N2O7/c1-2-30-21(28)18(12-15-8-10-17(26)11-9-15)23-20(27)19(13-25)24-22(29)31-14-16-6-4-3-5-7-16/h3-11,18-19,25-26H,2,12-14H2,1H3,(H,23,27)(H,24,29)/t18-,19-/m0/s1 PHLKAAWZXFTJPF-OALUTQOASA-N 50100020 (S)-2-((S)-2-Benzyloxycarbonylamino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionic acid ethyl ester::CHEMBL34175 C-C chemokine receptor type 3 Homo sapiens >25000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100020&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281365 103996836 CHEMBL34175 ZINC29224687 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180436 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Nc1ccccc1 InChI=1S/C18H20N2O4/c1-2-24-17(22)16(12-13-8-10-15(21)11-9-13)20-18(23)19-14-6-4-3-5-7-14/h3-11,16,21H,2,12H2,1H3,(H2,19,20,23)/t16-/m0/s1 MFMXOWCZHPKZGQ-INIZCTEOSA-N 50100023 (S)-3-(4-Hydroxy-phenyl)-2-(3-phenyl-ureido)-propionic acid ethyl ester::CHEMBL32107 C-C chemokine receptor type 3 Homo sapiens >33000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100023&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281598 103996839 CHEMBL32107 ZINC29226163 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180437 CCOC(=O)[C@H](Cc1ccc(O)cc1)NS(=O)(=O)c1ccc(C)cc1 InChI=1S/C18H21NO5S/c1-3-24-18(21)17(12-14-6-8-15(20)9-7-14)19-25(22,23)16-10-4-13(2)5-11-16/h4-11,17,19-20H,3,12H2,1-2H3/t17-/m0/s1 NNXLIBQGVVEZHL-KRWDZBQOSA-N 50100024 (S)-3-(4-Hydroxy-phenyl)-2-(toluene-4-sulfonylamino)-propionic acid ethyl ester::CHEMBL430745 C-C chemokine receptor type 3 Homo sapiens 16000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100024&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9907041 103996840 CHEMBL430745 ZINC01547158 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180438 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1 InChI=1S/C23H27N3O7/c1-2-32-22(30)19(12-15-8-10-17(27)11-9-15)25-21(29)18(13-20(24)28)26-23(31)33-14-16-6-4-3-5-7-16/h3-11,18-19,27H,2,12-14H2,1H3,(H2,24,28)(H,25,29)(H,26,31)/t18-,19-/m0/s1 SXRNCYAEBKYQNT-OALUTQOASA-N 50100022 2-((S)-2-Benzyloxycarbonylamino-3-carbamoyl-propionylamino)-3-(4-hydroxy-phenyl)-propionic acid (S)-ethyl ester::CHEMBL284372 C-C chemokine receptor type 3 Homo sapiens >25000 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100022&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281373 103996838 CHEMBL284372 ZINC29223787 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180439 CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc2ccccc12 InChI=1S/C22H21NO4/c1-2-27-22(26)20(14-15-10-12-17(24)13-11-15)23-21(25)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20,24H,2,14H2,1H3,(H,23,25)/t20-/m0/s1 BYICFESQQALZGO-FQEVSTJZSA-N 50100025 (S)-3-(4-Hydroxy-phenyl)-2-[(naphthalene-1-carbonyl)-amino]-propionic acid ethyl ester::CHEMBL290119 C-C chemokine receptor type 3 Homo sapiens 80 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100025&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9885355 103996841 CHEMBL290119 ZINC29225065 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193735 CCN(C1CCN(CCC(Cn2c(O)c(Cc3c[nH]c4ccccc34)[nH]c2=O)c2cccc(Cl)c2)CC1)C(=O)OCc1ccccc1 InChI=1S/C37H42ClN5O4/c1-2-42(37(46)47-25-26-9-4-3-5-10-26)31-16-19-41(20-17-31)18-15-28(27-11-8-12-30(38)21-27)24-43-35(44)34(40-36(43)45)22-29-23-39-33-14-7-6-13-32(29)33/h3-14,21,23,28,31,39,44H,2,15-20,22,24-25H2,1H3,(H,40,45) GPWGUUTTZSMWMP-UHFFFAOYSA-N 50106932 (1-{3-(3-Chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-butyl}-piperidin-4-yl)-ethyl-carbamic acid benzyl ester::CHEMBL105975 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106932&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931826 104002361 CHEMBL105975 ZINC26843052 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193737 CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)(Cn1c(O)c(Cc2c[nH]c3ccccc23)[nH]c1=O)c1cccc(Cl)c1 InChI=1S/C39H44ClN5O4/c1-3-19-44(38(48)49-26-28-10-5-4-6-11-28)32-16-20-43(21-17-32)22-18-39(2,30-12-9-13-31(40)24-30)27-45-36(46)35(42-37(45)47)23-29-25-41-34-15-8-7-14-33(29)34/h3-15,24-25,32,41,46H,1,16-23,26-27H2,2H3,(H,42,47) TTXCZSKJCTUHND-UHFFFAOYSA-N 50106938 Allyl-(1-{3-(3-chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester::CHEMBL107439 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106938&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931832 104002367 CHEMBL107439 ZINC26840863 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193740 CCN(C1CCN(CCC(C)(Cn2c(O)c(Cc3c[nH]c4ccccc34)[nH]c2=O)c2ccccc2)CC1)C(=O)OCc1ccccc1 InChI=1S/C38H45N5O4/c1-3-42(37(46)47-26-28-12-6-4-7-13-28)31-18-21-41(22-19-31)23-20-38(2,30-14-8-5-9-15-30)27-43-35(44)34(40-36(43)45)24-29-25-39-33-17-11-10-16-32(29)33/h4-17,25,31,39,44H,3,18-24,26-27H2,1-2H3,(H,40,45) XICJSXXAPJVMHS-UHFFFAOYSA-N 50106931 CHEMBL106907::Ethyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106931&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931825 104002360 CHEMBL106907 ZINC26840032 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193747 CCN(C1CCN(CCC(Cn2c(O)c(Cc3c[nH]c4ccccc34)[nH]c2=O)c2ccccc2)CC1)C(=O)OCc1ccccc1 InChI=1S/C37H43N5O4/c1-2-41(37(45)46-26-27-11-5-3-6-12-27)31-18-21-40(22-19-31)20-17-29(28-13-7-4-8-14-28)25-42-35(43)34(39-36(42)44)23-30-24-38-33-16-10-9-15-32(30)33/h3-16,24,29,31,38,43H,2,17-23,25-26H2,1H3,(H,39,44) VFJWEZDOYLGUHL-UHFFFAOYSA-N 50106934 CHEMBL317860::Ethyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106934&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931828 104002363 CHEMBL317860 ZINC26843063 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193751 Oc1c(Cc2c[nH]c3ccccc23)[nH]c(=O)n1CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)c1cccc(Cl)c1 InChI=1S/C38H42ClN5O4/c1-2-18-43(38(47)48-26-27-9-4-3-5-10-27)32-16-20-42(21-17-32)19-15-29(28-11-8-12-31(39)22-28)25-44-36(45)35(41-37(44)46)23-30-24-40-34-14-7-6-13-33(30)34/h2-14,22,24,29,32,40,45H,1,15-21,23,25-26H2,(H,41,46) SADUDVAXDUKTFI-UHFFFAOYSA-N 50106929 Allyl-(1-{3-(3-chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-butyl}-piperidin-4-yl)-carbamic acid benzyl ester::CHEMBL107128 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106929&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931823 104002358 CHEMBL107128 ZINC26840559 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193755 CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)(Cn1c(O)c(Cc2c[nH]c3ccccc23)[nH]c1=O)c1ccccc1 InChI=1S/C39H45N5O4/c1-3-21-43(38(47)48-27-29-12-6-4-7-13-29)32-18-22-42(23-19-32)24-20-39(2,31-14-8-5-9-15-31)28-44-36(45)35(41-37(44)46)25-30-26-40-34-17-11-10-16-33(30)34/h3-17,26,32,40,45H,1,18-25,27-28H2,2H3,(H,41,46) ZPUKCJCLSSHLSV-UHFFFAOYSA-N 50106930 Allyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester::CHEMBL104698 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106930&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931824 104002359 CHEMBL104698 ZINC26834505 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193761 Oc1c(Cc2c[nH]c3ccccc23)[nH]c(=O)n1CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)c1ccccc1 InChI=1S/C38H43N5O4/c1-2-20-42(38(46)47-27-28-11-5-3-6-12-28)32-18-22-41(23-19-32)21-17-30(29-13-7-4-8-14-29)26-43-36(44)35(40-37(43)45)24-31-25-39-34-16-10-9-15-33(31)34/h2-16,25,30,32,39,44H,1,17-24,26-27H2,(H,40,45) YLWMNMKULMUPMT-UHFFFAOYSA-N 50106939 Allyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester::CHEMBL104793 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00654-0 10.7270/Q2KK9B26 11720851 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106939&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91931833 104002368 CHEMBL104793 ZINC26834859 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193792 CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)(Cn1cnc2ccccc12)c1ccccc1 InChI=1S/C34H40N4O2/c1-3-21-38(33(39)40-25-28-12-6-4-7-13-28)30-18-22-36(23-19-30)24-20-34(2,29-14-8-5-9-15-29)26-37-27-35-31-16-10-11-17-32(31)37/h3-17,27,30H,1,18-26H2,2H3 BZHHPFLVFONUOE-UHFFFAOYSA-N 50106948 Allyl-[1-(4-benzoimidazol-1-yl-3-methyl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester::CHEMBL105659 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106948&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483343 104002377 CHEMBL105659 ZINC26832762 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193802 CCc1nc2ccccc2n1CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccc(cc1)[N+]([O-])=O)c1ccccc1 InChI=1S/C35H41N5O4/c1-3-21-38(35(41)44-26-27-14-16-31(17-15-27)40(42)43)30-19-23-37(24-20-30)22-18-29(28-10-6-5-7-11-28)25-39-33-13-9-8-12-32(33)36-34(39)4-2/h3,5-17,29-30H,1,4,18-26H2,2H3 GJIXUOZRDMDHKV-UHFFFAOYSA-N 50106949 Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester::CHEMBL319622 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106949&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483342 104002378 CHEMBL319622 ZINC26831128 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193806 C=CCN(C1CCN(CCC(Cn2cnc3ccccc23)c2ccccc2)CC1)C(=O)OCc1ccccc1 InChI=1S/C33H38N4O2/c1-2-20-37(33(38)39-25-27-11-5-3-6-12-27)30-18-22-35(23-19-30)21-17-29(28-13-7-4-8-14-28)24-36-26-34-31-15-9-10-16-32(31)36/h2-16,26,29-30H,1,17-25H2 LMLXAFRSRSRFFX-UHFFFAOYSA-N 50106947 Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester::CHEMBL104474 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106947&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483339 104002376 CHEMBL104474 ZINC26838149 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193807 CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccc(cc1)[N+]([O-])=O)(Cn1cnc2ccccc12)c1ccccc1 InChI=1S/C34H39N5O4/c1-3-20-38(33(40)43-24-27-13-15-30(16-14-27)39(41)42)29-17-21-36(22-18-29)23-19-34(2,28-9-5-4-6-10-28)25-37-26-35-31-11-7-8-12-32(31)37/h3-16,26,29H,1,17-25H2,2H3 ZEZTUVDVWYRRGY-UHFFFAOYSA-N 50106943 Allyl-[1-(4-benzoimidazol-1-yl-3-methyl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester::CHEMBL105570 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106943&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483344 104002372 CHEMBL105570 ZINC26831119 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193808 [O-][N+](=O)c1ccc(COC(=O)N(CC=C)C2CCN(CCC(Cn3cnc4ccccc34)c3ccccc3)CC2)cc1 InChI=1S/C33H37N5O4/c1-2-19-37(33(39)42-24-26-12-14-30(15-13-26)38(40)41)29-17-21-35(22-18-29)20-16-28(27-8-4-3-5-9-27)23-36-25-34-31-10-6-7-11-32(31)36/h2-15,25,28-29H,1,16-24H2 YQWSBFBPYMXNID-UHFFFAOYSA-N 50106952 Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester::CHEMBL106803 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106952&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483340 104002381 CHEMBL106803 ZINC14128287 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50193810 CCc1nc2ccccc2n1CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccccc1)c1ccccc1 InChI=1S/C35H42N4O2/c1-3-22-38(35(40)41-27-28-13-7-5-8-14-28)31-20-24-37(25-21-31)23-19-30(29-15-9-6-10-16-29)26-39-33-18-12-11-17-32(33)36-34(39)4-2/h3,5-18,30-31H,1,4,19-27H2,2H3 RBVAVRHWTOQOLQ-UHFFFAOYSA-N 50106945 Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester::CHEMBL321539 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/s0960-894x(01)00655-2 10.7270/Q2FT8K91 11720852 Kim, D; Wang, L; Caldwell, CG; Chen, P; Finke, PE; Oates, B; MacCoss, M; Mills, SG; Malkowitz, L; Gould, SL; DeMartino, JA; Springer, MS; Hazuda, D; Miller, M; Kessler, J; Danzeisen, R; Carver, G; Carella, A; Holmes, K; Lineberger, J; Schleif, WA; Emini, EA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106945&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 483341 104002374 CHEMBL321539 ZINC26838356 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208184 CS(=O)(=O)c1ccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C23H30FN3O3S/c1-31(29,30)22-9-7-21(8-10-22)26-23(28)25-13-2-14-27-15-11-19(12-16-27)17-18-3-5-20(24)6-4-18/h3-10,19H,2,11-17H2,1H3,(H2,25,26,28) MFAUISNSRCVPAJ-UHFFFAOYSA-N 50115008 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(4-methanesulfonyl-phenyl)-urea::CHEMBL51259 C-C chemokine receptor type 3 Homo sapiens 70.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115008&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295288 104008996 CHEMBL51259 ZINC13443534 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208185 O=C(NCCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-18-21-8-4-9-22(17-21)26-23(28)25-12-5-13-27-14-10-20(11-15-27)16-19-6-2-1-3-7-19/h1-4,6-9,17,20H,5,10-16H2,(H2,25,26,28) DFMMVTOIQOKHSC-UHFFFAOYSA-N 50115010 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-phenyl)-urea::CHEMBL42948 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115010&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9842640 104008998 CHEMBL42948 ZINC13443458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208186 COc1cccc(NC(=O)N2CCCC(C2)N2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C25H32FN3O2/c1-31-24-6-2-4-22(17-24)27-25(30)29-13-3-5-23(18-29)28-14-11-20(12-15-28)16-19-7-9-21(26)10-8-19/h2,4,6-10,17,20,23H,3,5,11-16,18H2,1H3,(H,27,30) KAGQMZHDWWRBEU-UHFFFAOYSA-N 50115009 4-(4-Fluoro-benzyl)-[1,3']bipiperidinyl-1'-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL50645 C-C chemokine receptor type 3 Homo sapiens 530 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115009&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295470 104008997 CHEMBL50645 ZINC13443598 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208187 Fc1ccc(cc1)C(=O)NCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C23H26FN3O/c24-18-7-5-17(6-8-18)23(28)25-11-2-12-26-13-10-21-20(15-26)19-4-1-3-16-9-14-27(21)22(16)19/h1,3-8,20-21H,2,9-15H2,(H,25,28)/t20-,21-/m1/s1 XLTOWXXETIFXGN-NHCUHLMSSA-N 50115011 4-Fluoro-N-[(6aR,10aS)-3-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-benzamide::CHEMBL51038 C-C chemokine receptor type 3 Homo sapiens 5500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115011&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295230 104008999 CHEMBL51038 ZINC13443402 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208189 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)-c3cccs3)CC2)cc1 InChI=1S/C26H30FN3OS/c27-23-9-7-20(8-10-23)18-21-11-15-30(16-12-21)14-3-13-28-26(31)29-24-5-1-4-22(19-24)25-6-2-17-32-25/h1-2,4-10,17,19,21H,3,11-16,18H2,(H2,28,29,31) YYWWCBOBWQSRAR-UHFFFAOYSA-N 50115014 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-thiophen-2-yl-phenyl)-urea::CHEMBL50129 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115014&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295406 104009002 CHEMBL50129 ZINC13443543 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208190 [O-][N+](=O)c1ccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C22H27FN4O3/c23-19-4-2-17(3-5-19)16-18-10-14-26(15-11-18)13-1-12-24-22(28)25-20-6-8-21(9-7-20)27(29)30/h2-9,18H,1,10-16H2,(H2,24,25,28) INZCTQNCULAMIV-UHFFFAOYSA-N 50115016 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(4-nitro-phenyl)-urea::CHEMBL299170 C-C chemokine receptor type 3 Homo sapiens 7.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115016&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295282 104009004 CHEMBL299170 C02125 ZINC13443502 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208192 O=C(NCCCCN1CCC(Cc2ccccc2)CC1)c1ccccc1 InChI=1S/C23H30N2O/c26-23(22-11-5-2-6-12-22)24-15-7-8-16-25-17-13-21(14-18-25)19-20-9-3-1-4-10-20/h1-6,9-12,21H,7-8,13-19H2,(H,24,26) CLFPTLFVCTUNRM-UHFFFAOYSA-N 50115013 CHEMBL50401::N-[4-(4-Benzyl-piperidin-1-yl)-butyl]-benzamide C-C chemokine receptor type 3 Homo sapiens 800 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115013&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295353 104009001 CHEMBL50401 ZINC13443563 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208193 COc1cccc(NC(=O)N2CCC(CN3CCC(Cc4ccccc4)CC3)CC2)c1 InChI=1S/C26H35N3O2/c1-31-25-9-5-8-24(19-25)27-26(30)29-16-12-23(13-17-29)20-28-14-10-22(11-15-28)18-21-6-3-2-4-7-21/h2-9,19,22-23H,10-18,20H2,1H3,(H,27,30) ODXLLUYBYOCBPG-UHFFFAOYSA-N 50115017 4-(4-Benzyl-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL54251 C-C chemokine receptor type 3 Homo sapiens 1600 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115017&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509664 104009005 CHEMBL54251 ZINC13443580 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208194 COc1cccc(NC(=O)N2CCCCC2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C26H34FN3O2/c1-32-25-7-4-5-23(18-25)28-26(31)30-14-3-2-6-24(30)19-29-15-12-21(13-16-29)17-20-8-10-22(27)11-9-20/h4-5,7-11,18,21,24H,2-3,6,12-17,19H2,1H3,(H,28,31) BSZULKCGCBLLIO-UHFFFAOYSA-N 50115018 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL51480 C-C chemokine receptor type 3 Homo sapiens 170 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115018&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295480 104009006 CHEMBL51480 ZINC13443610 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208195 FC(F)(F)c1ccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2)cc1 InChI=1S/C23H28F3N3O/c24-23(25,26)20-7-9-21(10-8-20)28-22(30)27-13-4-14-29-15-11-19(12-16-29)17-18-5-2-1-3-6-18/h1-3,5-10,19H,4,11-17H2,(H2,27,28,30) UZLFFYMRSYPRFX-UHFFFAOYSA-N 50115020 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL51113 C-C chemokine receptor type 3 Homo sapiens 1200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115020&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295372 104009008 CHEMBL51113 ZINC13443467 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208196 CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-4-2-5-23(17-21)27-24(30)26-12-3-13-28-14-10-20(11-15-28)16-19-6-8-22(25)9-7-19/h2,4-9,17,20H,3,10-16H2,1H3,(H2,26,27,30) JSUGTZOUOKXRQN-UHFFFAOYSA-N 50115023 1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295832 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115023&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393282 104009011 CHEMBL295832 ZINC13443505 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208197 O=C(NCCCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C24H30N4O/c25-19-22-9-6-10-23(18-22)27-24(29)26-13-4-5-14-28-15-11-21(12-16-28)17-20-7-2-1-3-8-20/h1-3,6-10,18,21H,4-5,11-17H2,(H2,26,27,29) HPLOYQYERAKCCS-UHFFFAOYSA-N 50115019 1-[4-(4-Benzyl-piperidin-1-yl)-butyl]-3-(3-cyano-phenyl)-urea::CHEMBL54143 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115019&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393398 104009007 CHEMBL54143 ZINC13443461 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208199 CC(=O)c1cccc(NC(=O)NCCCN2CC[C@H](Cc3ccccc3)C[C@@H]2C(C)(C)O)c1 InChI=1S/C27H37N3O3/c1-20(31)23-11-7-12-24(19-23)29-26(32)28-14-8-15-30-16-13-22(18-25(30)27(2,3)33)17-21-9-5-4-6-10-21/h4-7,9-12,19,22,25,33H,8,13-18H2,1-3H3,(H2,28,29,32)/t22-,25-/m1/s1 AXUHRCROLFVLAP-RCZVLFRGSA-N 50115022 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-(1-hydroxy-1-methyl-ethyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51052 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115022&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295304 104009010 CHEMBL51052 ZINC13443653 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208200 COc1cccc(NC(=O)N2CCO[C@H](CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H32FN3O3/c1-31-23-4-2-3-22(16-23)27-25(30)29-13-14-32-24(18-29)17-28-11-9-20(10-12-28)15-19-5-7-21(26)8-6-19/h2-8,16,20,24H,9-15,17-18H2,1H3,(H,27,30)/t24-/m1/s1 CBNWNPGNUKPULD-XMMPIXPASA-N 50115025 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-morpholine-4-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL298505 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115025&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295434 104009013 CHEMBL298505 ZINC13443621 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208201 Ic1ccc(NC(=O)NCCCN2CC[C@@H]3[C@H](C2)c2cccc4CCN3c24)cc1 InChI=1S/C23H27IN4O/c24-17-5-7-18(8-6-17)26-23(29)25-11-2-12-27-13-10-21-20(15-27)19-4-1-3-16-9-14-28(21)22(16)19/h1,3-8,20-21H,2,9-15H2,(H2,25,26,29)/t20-,21-/m1/s1 ZHFUJRBAYSOUBG-NHCUHLMSSA-N 50115024 1-[(6aR,10aS)-3-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-3-(4-iodo-phenyl)-urea::CHEMBL51953 C-C chemokine receptor type 3 Homo sapiens 1500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115024&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295145 104009012 CHEMBL51953 ZINC13443446 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208202 Fc1ccc(CC2CCN(CCCNC(=O)Nc3ccccc3)CC2)cc1 InChI=1S/C22H28FN3O/c23-20-9-7-18(8-10-20)17-19-11-15-26(16-12-19)14-4-13-24-22(27)25-21-5-2-1-3-6-21/h1-3,5-10,19H,4,11-17H2,(H2,24,25,27) QHSIDOWZSDCHKB-UHFFFAOYSA-N 50115027 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-phenyl-urea::CHEMBL416305 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115027&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295362 104009015 CHEMBL416305 ZINC13443473 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208203 CC(C)C[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C29H41N3O3/c1-21(2)17-28(34)27-19-24(18-23-9-5-4-6-10-23)13-16-32(27)15-8-14-30-29(35)31-26-12-7-11-25(20-26)22(3)33/h4-7,9-12,20-21,24,27-28,34H,8,13-19H2,1-3H3,(H2,30,31,35)/t24-,27-,28+/m1/s1 YSUSWOLSOLLLPR-RTVRTQBESA-N 50115026 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-3-methyl-butyl)-piperidin-1-yl]-propyl}-urea::CHEMBL53444 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115026&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295566 104009014 CHEMBL53444 ZINC13443672 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208204 Fc1ccc(cc1)C(=O)NCCCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H29FN2O/c24-22-10-8-21(9-11-22)23(27)25-14-4-5-15-26-16-12-20(13-17-26)18-19-6-2-1-3-7-19/h1-3,6-11,20H,4-5,12-18H2,(H,25,27) BXECEDOJJMPMNB-UHFFFAOYSA-N 50115029 CHEMBL49296::N-[4-(4-Benzyl-piperidin-1-yl)-butyl]-4-fluoro-benzamide C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115029&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295529 104009017 CHEMBL49296 ZINC13443572 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208205 Fc1ccc(CC2CCN(CCCNC(=O)NC3CCCCC3)CC2)cc1 InChI=1S/C22H34FN3O/c23-20-9-7-18(8-10-20)17-19-11-15-26(16-12-19)14-4-13-24-22(27)25-21-5-2-1-3-6-21/h7-10,19,21H,1-6,11-17H2,(H2,24,25,27) KMMVEHIYOWBLGW-UHFFFAOYSA-N 50115030 1-Cyclohexyl-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51229 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115030&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393436 104009018 CHEMBL51229 ZINC03976327 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208206 Clc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C23H27ClN4O/c24-21-7-5-18(6-8-21)15-19-9-13-28(14-10-19)12-2-11-26-23(29)27-22-4-1-3-20(16-22)17-25/h1,3-8,16,19H,2,9-15H2,(H2,26,27,29) QPYSQIOCOXFUJE-UHFFFAOYSA-N 50115031 1-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-propyl}-3-(3-cyano-phenyl)-urea::CHEMBL48873 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115031&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393339 104009019 CHEMBL48873 ZINC13443557 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208207 Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-4-2-5-22(17-20)27-24(33)26-12-3-13-32-14-10-19(11-15-32)16-18-6-8-21(25)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,26,27,33) NBCZORXSDNGHOO-UHFFFAOYSA-N 50115032 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43173 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115032&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393287 104009020 CHEMBL43173 ZINC13443551 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208208 O=C(NCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C22H26N4O/c23-17-20-7-4-8-21(16-20)25-22(27)24-11-14-26-12-9-19(10-13-26)15-18-5-2-1-3-6-18/h1-8,16,19H,9-15H2,(H2,24,25,27) XUWJPTFGWKOYSP-UHFFFAOYSA-N 50115028 1-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-3-(3-cyano-phenyl)-urea::CHEMBL295726 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115028&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295130 104009016 CHEMBL295726 ZINC13443455 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208209 CN(C)c1ccc(NC(=O)NCCCN2CC[C@@H]3[C@H](C2)c2cccc4CCN3c24)cc1 InChI=1S/C25H33N5O/c1-28(2)20-9-7-19(8-10-20)27-25(31)26-13-4-14-29-15-12-23-22(17-29)21-6-3-5-18-11-16-30(23)24(18)21/h3,5-10,22-23H,4,11-17H2,1-2H3,(H2,26,27,31)/t22-,23-/m1/s1 JHMQJHNRUFSOMK-DHIUTWEWSA-N 50115035 1-(4-Dimethylamino-phenyl)-3-[(6aR,10aS)-3-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-urea::CHEMBL433086 C-C chemokine receptor type 3 Homo sapiens 4800 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115035&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295375 104009023 CHEMBL433086 ZINC13443432 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208210 CC(=O)c1ccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C24H30FN3O2/c1-18(29)21-5-9-23(10-6-21)27-24(30)26-13-2-14-28-15-11-20(12-16-28)17-19-3-7-22(25)8-4-19/h3-10,20H,2,11-17H2,1H3,(H2,26,27,30) RJTCZABUFMJLNH-UHFFFAOYSA-N 50115036 1-(4-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL52094 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115036&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393366 104009024 CHEMBL52094 ZINC13443508 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208211 CC[C@@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O3/c1-3-26(32)25-18-22(17-21-9-5-4-6-10-21)13-16-30(25)15-8-14-28-27(33)29-24-12-7-11-23(19-24)20(2)31/h4-7,9-12,19,22,25-26,32H,3,8,13-18H2,1-2H3,(H2,28,29,33)/t22-,25-,26?/m1/s1 UEKNCACYTQCRSI-NQXVELOOSA-N 50115034 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((R)-1-hydroxy-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL54290 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115034&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9868459 104009022 CHEMBL54290 ZINC13443660 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208213 C[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C26H35N3O3/c1-19(30)23-10-6-11-24(18-23)28-26(32)27-13-7-14-29-15-12-22(17-25(29)20(2)31)16-21-8-4-3-5-9-21/h3-6,8-11,18,20,22,25,31H,7,12-17H2,1-2H3,(H2,27,28,32)/t20-,22+,25+/m0/s1 IJDYYTNTHROURD-NIRIFSCTSA-N 50115033 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-ethyl)-piperidin-1-yl]-propyl}-urea::CHEMBL301601 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115033&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295648 104009021 CHEMBL301601 ZINC13443647 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208214 O=C(NCCCCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C25H32N4O/c26-20-23-10-7-11-24(19-23)28-25(30)27-14-5-2-6-15-29-16-12-22(13-17-29)18-21-8-3-1-4-9-21/h1,3-4,7-11,19,22H,2,5-6,12-18H2,(H2,27,28,30) XIKCHHFMJZCKKA-UHFFFAOYSA-N 50115038 1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-3-(3-cyano-phenyl)-urea::CHEMBL298681 C-C chemokine receptor type 3 Homo sapiens 1200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115038&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295374 104009026 CHEMBL298681 ZINC13443464 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208215 CS(=O)c1ccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C23H30FN3O2S/c1-30(29)22-9-7-21(8-10-22)26-23(28)25-13-2-14-27-15-11-19(12-16-27)17-18-3-5-20(24)6-4-18/h3-10,19H,2,11-17H2,1H3,(H2,25,26,28) BZUPVDKJCJGJBP-UHFFFAOYSA-N 50115039 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(4-methanesulfinyl-phenyl)-urea::CHEMBL49938 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115039&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295267 104009027 CHEMBL49938 ZINC13443531 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208216 Fc1ccc(cc1)S(=O)(=O)NCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C22H26FN3O2S/c23-17-5-7-18(8-6-17)29(27,28)24-11-2-12-25-13-10-21-20(15-25)19-4-1-3-16-9-14-26(21)22(16)19/h1,3-8,20-21,24H,2,9-15H2/t20-,21-/m1/s1 CMKNQJOAZVUIFF-NHCUHLMSSA-N 50115040 4-Fluoro-N-[(6aR,10aS)-3-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-benzenesulfonamide::CHEMBL51512 C-C chemokine receptor type 3 Homo sapiens 10100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115040&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295435 104009028 CHEMBL51512 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208217 Ic1cccc(NC(=O)NCCCN2CC[C@@H]3[C@H](C2)c2cccc4CCN3c24)c1 InChI=1S/C23H27IN4O/c24-17-5-2-6-18(14-17)26-23(29)25-10-3-11-27-12-9-21-20(15-27)19-7-1-4-16-8-13-28(21)22(16)19/h1-2,4-7,14,20-21H,3,8-13,15H2,(H2,25,26,29)/t20-,21-/m1/s1 CEMHMXWUBPDAQL-NHCUHLMSSA-N 50115043 1-[(6aR,10aS)-3-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-3-(3-iodo-phenyl)-urea::CHEMBL297945 C-C chemokine receptor type 3 Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115043&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295486 104009031 CHEMBL297945 ZINC13443443 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208218 O=C(NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13)C12CC3CC(CC(C3)C1)C2 InChI=1S/C28H39N3O/c32-27(28-15-19-12-20(16-28)14-21(13-19)17-28)29-8-1-2-9-30-10-7-25-24(18-30)23-5-3-4-22-6-11-31(25)26(22)23/h3-5,19-21,24-25H,1-2,6-18H2,(H,29,32)/t19?,20?,21?,24-,25-,28?/m1/s1 SYGPRZVXACOFFG-NCNWNLKQSA-N 50115041 Adamantane-1-carboxylic acid [(6aR,10aS)-4-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-amide::CHEMBL51507 C-C chemokine receptor type 3 Homo sapiens 6600 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115041&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295407 104009029 CHEMBL51507 ZINC13443420 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208219 O=C(NCCCN1CCC(Cc2ccccc2)CC1)Nc1ccccc1 InChI=1S/C22H29N3O/c26-22(24-21-10-5-2-6-11-21)23-14-7-15-25-16-12-20(13-17-25)18-19-8-3-1-4-9-19/h1-6,8-11,20H,7,12-18H2,(H2,23,24,26) BKQLADJYVXOCJW-UHFFFAOYSA-N 50115042 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-phenyl-urea::CHEMBL51307 C-C chemokine receptor type 3 Homo sapiens 400 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115042&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393333 104009030 CHEMBL51307 ZINC13443448 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208220 Fc1ccc(CCCN2CC[C@@H]3[C@H](C2)c2cccc4CCN3c24)cc1 InChI=1S/C22H25FN2/c23-18-8-6-16(7-9-18)3-2-12-24-13-11-21-20(15-24)19-5-1-4-17-10-14-25(21)22(17)19/h1,4-9,20-21H,2-3,10-15H2/t20-,21-/m1/s1 GCWSOKYFEWNCMI-NHCUHLMSSA-N 50115045 (6aR,10aS)-9-[3-(4-Fluoro-phenyl)-propyl]-4,5,6a,7,8,9,10,10a-octahydro-pyrido[4,3-b]pyrrolo[3,2,1-hi]indole::CHEMBL300905 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115045&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295528 104009033 CHEMBL300905 ZINC13443393 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208221 CC(C)C[C@@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C29H41N3O3/c1-21(2)17-28(34)27-19-24(18-23-9-5-4-6-10-23)13-16-32(27)15-8-14-30-29(35)31-26-12-7-11-25(20-26)22(3)33/h4-7,9-12,20-21,24,27-28,34H,8,13-19H2,1-3H3,(H2,30,31,35)/t24-,27-,28?/m1/s1 YSUSWOLSOLLLPR-GJSYQGSMSA-N 50115044 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((R)-1-hydroxy-3-methyl-butyl)-piperidin-1-yl]-propyl}-urea::CHEMBL446144 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115044&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295201 104009032 CHEMBL446144 ZINC13443675 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208222 O=C(NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13)C1CCCCC1 InChI=1S/C24H35N3O/c28-24(19-7-2-1-3-8-19)25-13-4-5-14-26-15-12-22-21(17-26)20-10-6-9-18-11-16-27(22)23(18)20/h6,9-10,19,21-22H,1-5,7-8,11-17H2,(H,25,28)/t21-,22-/m1/s1 AOIYRGJEOWHRNF-FGZHOGPDSA-N 50115046 CHEMBL50591::Cyclohexanecarboxylic acid [(6aR,10aS)-4-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-amide C-C chemokine receptor type 3 Homo sapiens 11000 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115046&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295408 104009034 CHEMBL50591 ZINC13443416 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208223 CSc1ccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C23H30FN3OS/c1-29-22-9-7-21(8-10-22)26-23(28)25-13-2-14-27-15-11-19(12-16-27)17-18-3-5-20(24)6-4-18/h3-10,19H,2,11-17H2,1H3,(H2,25,26,28) SLNJDPRNFIRCIP-UHFFFAOYSA-N 50115052 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(4-methylsulfanyl-phenyl)-urea::CHEMBL50094 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115052&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295554 104009040 CHEMBL50094 ZINC13443525 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208224 Fc1ccc(CC2CCN(CCCNC(=O)NCCc3ccccc3)CC2)cc1 InChI=1S/C24H32FN3O/c25-23-9-7-21(8-10-23)19-22-12-17-28(18-13-22)16-4-14-26-24(29)27-15-11-20-5-2-1-3-6-20/h1-3,5-10,22H,4,11-19H2,(H2,26,27,29) VKPCYODWIYLFDI-UHFFFAOYSA-N 50115050 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-phenethyl-urea::CHEMBL50829 C-C chemokine receptor type 3 Homo sapiens 300 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115050&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393378 104009038 CHEMBL50829 ZINC13443479 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208225 O=C(NCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13)Nc1cccc(c1)C#N InChI=1S/C24H27N5O/c25-15-17-4-1-6-19(14-17)27-24(30)26-10-3-11-28-12-9-22-21(16-28)20-7-2-5-18-8-13-29(22)23(18)20/h1-2,4-7,14,21-22H,3,8-13,16H2,(H2,26,27,30)/t21-,22-/m1/s1 LKTPZBZRWBHLAW-FGZHOGPDSA-N 50115049 1-(3-Cyano-phenyl)-3-[(6aR,10aS)-3-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-urea::CHEMBL300472 C-C chemokine receptor type 3 Homo sapiens 700 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115049&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295510 104009037 CHEMBL300472 ZINC13443439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208227 Fc1ccc(CC2CCN(CCCNC(=O)NCc3ccccc3)CC2)cc1 InChI=1S/C23H30FN3O/c24-22-9-7-19(8-10-22)17-20-11-15-27(16-12-20)14-4-13-25-23(28)26-18-21-5-2-1-3-6-21/h1-3,5-10,20H,4,11-18H2,(H2,25,26,28) MLOQSCVFJJQLDB-UHFFFAOYSA-N 50115048 1-Benzyl-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50354 C-C chemokine receptor type 3 Homo sapiens 400 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115048&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393428 104009036 CHEMBL50354 ZINC13443476 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208229 Fc1ccc(CC2CCN(CCCNC(=O)Nc3ccccc3C(F)(F)F)CC2)cc1 InChI=1S/C23H27F4N3O/c24-19-8-6-17(7-9-19)16-18-10-14-30(15-11-18)13-3-12-28-22(31)29-21-5-2-1-4-20(21)23(25,26)27/h1-2,4-9,18H,3,10-16H2,(H2,28,29,31) BKGDSYCWICQSPA-UHFFFAOYSA-N 50115054 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(2-trifluoromethyl-phenyl)-urea::CHEMBL299385 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115054&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393362 104009042 CHEMBL299385 ZINC13443487 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208230 CS(=O)(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C23H30FN3O3S/c1-31(29,30)22-5-2-4-21(17-22)26-23(28)25-12-3-13-27-14-10-19(11-15-27)16-18-6-8-20(24)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,25,26,28) BZJSHEKGGJTWLW-UHFFFAOYSA-N 50115055 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-methanesulfonyl-phenyl)-urea::CHEMBL301974 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115055&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295555 104009043 CHEMBL301974 ZINC13443522 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208231 CCCC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C29H41N7O2/c1-3-4-14-27(37)26-20-23(19-22-10-6-5-7-11-22)15-18-36(26)17-9-16-30-29(38)31-25-13-8-12-24(21-25)28-32-33-34-35(28)2/h5-8,10-13,21,23,26-27,37H,3-4,9,14-20H2,1-2H3,(H2,30,31,38)/t23-,26-,27+/m1/s1 BAAFLUWVDPBRCL-MVNQZMKCSA-N 50115051 1-{3-[(2R,4S)-4-Benzyl-2-((S)-1-hydroxy-pentyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL50194 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115051&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295462 104009039 CHEMBL50194 ZINC13443687 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208233 CCC[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O2/c1-3-9-26-19-23(18-22-10-5-4-6-11-22)14-17-30(26)16-8-15-28-27(32)29-25-13-7-12-24(20-25)21(2)31/h4-7,10-13,20,23,26H,3,8-9,14-19H2,1-2H3,(H2,28,29,32)/t23-,26+/m1/s1 LSVGDBOAFGMALQ-BVAGGSTKSA-N 50115037 1-(3-Acetyl-phenyl)-3-[3-((2S,4S)-4-benzyl-2-propyl-piperidin-1-yl)-propyl]-urea::CHEMBL50423 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115037&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295664 104009025 CHEMBL50423 ZINC13443638 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208234 [O-][N+](=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C22H27FN4O3/c23-19-7-5-17(6-8-19)15-18-9-13-26(14-10-18)12-2-11-24-22(28)25-20-3-1-4-21(16-20)27(29)30/h1,3-8,16,18H,2,9-15H2,(H2,24,25,28) ZRARJHMTWPDSFU-UHFFFAOYSA-N 50115056 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-nitro-phenyl)-urea::CHEMBL439744 C-C chemokine receptor type 3 Homo sapiens 9.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115056&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295326 104009044 CHEMBL439744 ZINC13443499 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208235 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C(F)(F)F)CC2)cc1 InChI=1S/C23H27F4N3O/c24-20-7-5-17(6-8-20)15-18-9-13-30(14-10-18)12-2-11-28-22(31)29-21-4-1-3-19(16-21)23(25,26)27/h1,3-8,16,18H,2,9-15H2,(H2,28,29,31) APVMWUNIKUFKIJ-UHFFFAOYSA-N 50115057 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-trifluoromethyl-phenyl)-urea::CHEMBL262918 C-C chemokine receptor type 3 Homo sapiens 70.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115057&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393474 104009045 CHEMBL262918 ZINC13443490 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208236 Cc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C24H30N4O/c1-19-6-8-20(9-7-19)16-21-10-14-28(15-11-21)13-3-12-26-24(29)27-23-5-2-4-22(17-23)18-25/h2,4-9,17,21H,3,10-16H2,1H3,(H2,26,27,29) MWXMIUQKKOBQAH-UHFFFAOYSA-N 50115059 1-(3-Cyano-phenyl)-3-{3-[4-(4-methyl-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51676 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115059&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393370 104009047 CHEMBL51676 ZINC13443560 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208238 COc1cccc(NC(=O)N2CCCC(CN3CCC(Cc4ccccc4)CC3)C2)c1 InChI=1S/C26H35N3O2/c1-31-25-11-5-10-24(18-25)27-26(30)29-14-6-9-23(20-29)19-28-15-12-22(13-16-28)17-21-7-3-2-4-8-21/h2-5,7-8,10-11,18,22-23H,6,9,12-17,19-20H2,1H3,(H,27,30) CAAKBYBXQYVPII-UHFFFAOYSA-N 50115060 3-(4-Benzyl-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL300726 C-C chemokine receptor type 3 Homo sapiens 330 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115060&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9888454 104009048 CHEMBL300726 ZINC13443586 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208239 CC(C)[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C28H39N3O3/c1-20(2)27(33)26-18-23(17-22-9-5-4-6-10-22)13-16-31(26)15-8-14-29-28(34)30-25-12-7-11-24(19-25)21(3)32/h4-7,9-12,19-20,23,26-27,33H,8,13-18H2,1-3H3,(H2,29,30,34)/t23-,26-,27+/m1/s1 RRNALAYMXGNJNS-MVNQZMKCSA-N 50115061 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-2-methyl-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL297904 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115061&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295622 104009049 CHEMBL297904 ZINC13443663 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208240 COc1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C23H30FN3O2/c1-29-22-5-2-4-21(17-22)26-23(28)25-12-3-13-27-14-10-19(11-15-27)16-18-6-8-20(24)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,25,26,28) JXTQWHXHDNHUMI-UHFFFAOYSA-N 50115071 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-methoxy-phenyl)-urea::CHEMBL42388 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115071&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393419 104009059 CHEMBL42388 ZINC13443536 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208241 Fc1ccc(cc1)S(=O)(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C23H28FN3O2S/c24-18-6-8-19(9-7-18)30(28,29)25-12-1-2-13-26-14-11-22-21(16-26)20-5-3-4-17-10-15-27(22)23(17)20/h3-9,21-22,25H,1-2,10-16H2/t21-,22-/m1/s1 RDGKSJPQKMCGPY-FGZHOGPDSA-N 50115062 4-Fluoro-N-[(6aR,10aS)-4-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-benzenesulfonamide::CHEMBL415950 C-C chemokine receptor type 3 Homo sapiens 6400 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115062&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295463 104009050 CHEMBL415950 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208243 CCCC[C@H](O)[C@H]1C[C@@H](Cc2ccc(F)cc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C29H40FN3O3/c1-3-4-9-28(35)27-19-23(18-22-10-12-25(30)13-11-22)14-17-33(27)16-6-15-31-29(36)32-26-8-5-7-24(20-26)21(2)34/h5,7-8,10-13,20,23,27-28,35H,3-4,6,9,14-19H2,1-2H3,(H2,31,32,36)/t23-,27-,28+/m1/s1 LBZQIGRJYPPJEU-QPVYNBJUSA-N 50115064 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-(4-fluoro-benzyl)-2-((S)-1-hydroxy-pentyl)-piperidin-1-yl]-propyl}-urea::CHEMBL300699 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115064&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295485 104009052 CHEMBL300699 ZINC13443690 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208244 Fc1ccc(CC2CCN(CCCNC(=O)NC34CC5CC(CC(C5)C3)C4)CC2)cc1 InChI=1S/C26H38FN3O/c27-24-4-2-19(3-5-24)12-20-6-10-30(11-7-20)9-1-8-28-25(31)29-26-16-21-13-22(17-26)15-23(14-21)18-26/h2-5,20-23H,1,6-18H2,(H2,28,29,31) NAPUJZZCCVJTMV-UHFFFAOYSA-N 50115063 1-Adamantan-1-yl-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL301503 C-C chemokine receptor type 3 Homo sapiens 90 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115063&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295543 104009051 CHEMBL301503 ZINC13443575 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208245 COc1cccc(c1)C(=O)NCCCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C24H32N2O2/c1-28-23-11-7-10-22(19-23)24(27)25-14-5-6-15-26-16-12-21(13-17-26)18-20-8-3-2-4-9-20/h2-4,7-11,19,21H,5-6,12-18H2,1H3,(H,25,27) CVTGZSHIONODBU-UHFFFAOYSA-N 50115058 CHEMBL50400::N-[4-(4-Benzyl-piperidin-1-yl)-butyl]-3-methoxy-benzamide C-C chemokine receptor type 3 Homo sapiens 1200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115058&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295352 104009046 CHEMBL50400 ZINC13443566 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208246 Fc1ccc(cc1)C(=O)CCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C23H25FN2O/c24-18-8-6-16(7-9-18)22(27)5-2-12-25-13-11-21-20(15-25)19-4-1-3-17-10-14-26(21)23(17)19/h1,3-4,6-9,20-21H,2,5,10-15H2/t20-,21-/m1/s1 VFYQZTSTHAKQER-NHCUHLMSSA-N 50115072 1-(4-Fluoro-phenyl)-4-(6aR,10aS)-4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl-butan-1-one::CHEMBL51163 C-C chemokine receptor type 3 Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115072&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 20576924 104009060 CHEMBL51163 ZINC13443396 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208247 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)-c3ncc[nH]3)CC2)cc1 InChI=1S/C25H30FN5O/c26-22-7-5-19(6-8-22)17-20-9-15-31(16-10-20)14-2-11-29-25(32)30-23-4-1-3-21(18-23)24-27-12-13-28-24/h1,3-8,12-13,18,20H,2,9-11,14-17H2,(H,27,28)(H2,29,30,32) CFTGTDFHYVRNEP-UHFFFAOYSA-N 50115068 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1H-imidazol-2-yl)-phenyl]-urea::CHEMBL50988 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115068&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295405 104009056 CHEMBL50988 ZINC13443548 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208248 COc1ccccc1C(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C25H31N3O2/c1-30-23-10-3-2-8-20(23)25(29)26-13-4-5-14-27-15-12-22-21(17-27)19-9-6-7-18-11-16-28(22)24(18)19/h2-3,6-10,21-22H,4-5,11-17H2,1H3,(H,26,29)/t21-,22-/m1/s1 DXZJHXCWMNHGMS-FGZHOGPDSA-N 50115073 CHEMBL48401::N-[(6aR,10aS)-4-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-2-methoxy-benzamide C-C chemokine receptor type 3 Homo sapiens 6800 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115073&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295065 104009061 CHEMBL48401 ZINC13443422 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208249 CN(C)c1ccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2)cc1 InChI=1S/C24H34N4O/c1-27(2)23-11-9-22(10-12-23)26-24(29)25-15-6-16-28-17-13-21(14-18-28)19-20-7-4-3-5-8-20/h3-5,7-12,21H,6,13-19H2,1-2H3,(H2,25,26,29) WXIWAAYRLIHEQS-UHFFFAOYSA-N 50115067 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(4-dimethylamino-phenyl)-urea::CHEMBL51110 C-C chemokine receptor type 3 Homo sapiens 1600 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115067&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295354 104009055 CHEMBL51110 ZINC13443470 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208250 COc1cccc(c1)C(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C25H31N3O2/c1-30-20-8-4-7-19(16-20)25(29)26-12-2-3-13-27-14-11-23-22(17-27)21-9-5-6-18-10-15-28(23)24(18)21/h4-9,16,22-23H,2-3,10-15,17H2,1H3,(H,26,29)/t22-,23-/m1/s1 SKQGTANPXDIZKT-DHIUTWEWSA-N 50115070 CHEMBL50937::N-[(6aR,10aS)-4-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-3-methoxy-benzamide C-C chemokine receptor type 3 Homo sapiens 8100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115070&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295118 104009058 CHEMBL50937 ZINC13443425 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208252 Fc1ccc(cc1)C(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C24H28FN3O/c25-19-8-6-18(7-9-19)24(29)26-12-1-2-13-27-14-11-22-21(16-27)20-5-3-4-17-10-15-28(22)23(17)20/h3-9,21-22H,1-2,10-16H2,(H,26,29)/t21-,22-/m1/s1 ACSDIWKSDYFXHI-FGZHOGPDSA-N 50115065 4-Fluoro-N-[(6aR,10aS)-4-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-benzamide::CHEMBL416835 C-C chemokine receptor type 3 Homo sapiens 3900 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115065&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295259 104009053 CHEMBL416835 ZINC13443405 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208253 O=C(NCCCCN1CCC(Cc2ccccc2)CC1)c1ccc(cc1)C#N InChI=1S/C24H29N3O/c25-19-22-8-10-23(11-9-22)24(28)26-14-4-5-15-27-16-12-21(13-17-27)18-20-6-2-1-3-7-20/h1-3,6-11,21H,4-5,12-18H2,(H,26,28) IMOJUBIDGIQNIK-UHFFFAOYSA-N 50115066 CHEMBL50801::N-[4-(4-Benzyl-piperidin-1-yl)-butyl]-4-cyano-benzamide C-C chemokine receptor type 3 Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115066&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295544 104009054 CHEMBL50801 ZINC13443569 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208254 CC(C)(C)C(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C22H33N3O/c1-22(2,3)21(26)23-11-4-5-12-24-13-10-19-18(15-24)17-8-6-7-16-9-14-25(19)20(16)17/h6-8,18-19H,4-5,9-15H2,1-3H3,(H,23,26)/t18-,19-/m1/s1 DPPCNMGUWQNGFW-RTBURBONSA-N 50115075 CHEMBL299226::N-[(6aR,10aS)-4-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-2,2-dimethyl-propionamide C-C chemokine receptor type 3 Homo sapiens 25600 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115075&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295409 104009063 CHEMBL299226 ZINC13443413 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208255 Fc1ccc(cc1)C(=O)NCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C22H24FN3O/c23-17-6-4-16(5-7-17)22(27)24-10-13-25-11-9-20-19(14-25)18-3-1-2-15-8-12-26(20)21(15)18/h1-7,19-20H,8-14H2,(H,24,27)/t19-,20-/m1/s1 CSZLRTXLHDVGDH-WOJBJXKFSA-N 50115069 4-Fluoro-N-[(6aR,10aS)-2-(4,5,7,8,10,10a-hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-ethyl]-benzamide::CHEMBL301332 C-C chemokine receptor type 3 Homo sapiens 8300.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115069&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295558 104009057 CHEMBL301332 ZINC13443399 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208256 Fc1ccccc1CC1CCN(CCCNC(=O)Nc2cccc(c2)C#N)CC1 InChI=1S/C23H27FN4O/c24-22-8-2-1-6-20(22)15-18-9-13-28(14-10-18)12-4-11-26-23(29)27-21-7-3-5-19(16-21)17-25/h1-3,5-8,16,18H,4,9-15H2,(H2,26,27,29) KLCUVTDKNOWQIN-UHFFFAOYSA-N 50115074 1-(3-Cyano-phenyl)-3-{3-[4-(2-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50557 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115074&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393307 104009062 CHEMBL50557 ZINC13443554 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208257 CCC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C28H39N3O3/c1-3-9-27(33)26-19-23(18-22-10-5-4-6-11-22)14-17-31(26)16-8-15-29-28(34)30-25-13-7-12-24(20-25)21(2)32/h4-7,10-13,20,23,26-27,33H,3,8-9,14-19H2,1-2H3,(H2,29,30,34)/t23-,26-,27+/m1/s1 ARPXRILPIHWQDL-MVNQZMKCSA-N 50115084 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-butyl)-piperidin-1-yl]-propyl}-urea::CHEMBL49921 C-C chemokine receptor type 3 Homo sapiens 7.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115084&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295591 104009072 CHEMBL49921 ZINC13443669 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208258 Fc1ccc(CC2CCN(CCCNC(=O)Nc3ccc(cc3)C(F)(F)F)CC2)cc1 InChI=1S/C23H27F4N3O/c24-20-6-2-17(3-7-20)16-18-10-14-30(15-11-18)13-1-12-28-22(31)29-21-8-4-19(5-9-21)23(25,26)27/h2-9,18H,1,10-16H2,(H2,28,29,31) DFBQHFGWJQZXSF-UHFFFAOYSA-N 50115085 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL53673 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115085&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295328 104009073 CHEMBL53673 ZINC13443493 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208259 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)-c3ccco3)CC2)cc1 InChI=1S/C26H30FN3O2/c27-23-9-7-20(8-10-23)18-21-11-15-30(16-12-21)14-3-13-28-26(31)29-24-5-1-4-22(19-24)25-6-2-17-32-25/h1-2,4-10,17,19,21H,3,11-16,18H2,(H2,28,29,31) LDQNXVYONJHDQT-UHFFFAOYSA-N 50115083 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-furan-2-yl-phenyl)-urea::CHEMBL49404 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115083&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295264 104009071 CHEMBL49404 ZINC13443540 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208260 COc1ccc(cc1)C(=O)NCCCCN1CC[C@@H]2[C@H](C1)c1cccc3CCN2c13 InChI=1S/C25H31N3O2/c1-30-20-9-7-19(8-10-20)25(29)26-13-2-3-14-27-15-12-23-22(17-27)21-6-4-5-18-11-16-28(23)24(18)21/h4-10,22-23H,2-3,11-17H2,1H3,(H,26,29)/t22-,23-/m1/s1 HNOVOHJDSAITPA-DHIUTWEWSA-N 50115086 CHEMBL49702::N-[(6aR,10aS)-4-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-butyl]-4-methoxy-benzamide C-C chemokine receptor type 3 Homo sapiens 5100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115086&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295102 104009074 CHEMBL49702 ZINC13443429 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208261 CC(=O)c1cccc(NC(=O)NCCCN2CC[C@H](Cc3ccccc3)C[C@@H]2Cc2ccccc2)c1 InChI=1S/C31H37N3O2/c1-24(35)28-14-8-15-29(23-28)33-31(36)32-17-9-18-34-19-16-27(20-25-10-4-2-5-11-25)22-30(34)21-26-12-6-3-7-13-26/h2-8,10-15,23,27,30H,9,16-22H2,1H3,(H2,32,33,36)/t27-,30+/m1/s1 JWLOKPWVWUXPIX-OFSOJUDTSA-N 50115080 1-(3-Acetyl-phenyl)-3-[3-((2R,4S)-2,4-dibenzyl-piperidin-1-yl)-propyl]-urea::CHEMBL298999 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115080&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295674 104009068 CHEMBL298999 ZINC13443644 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208264 FC(F)(F)c1ccc(NC(=O)NCCCN2CC[C@@H]3[C@H](C2)c2cccc4CCN3c24)cc1 InChI=1S/C24H27F3N4O/c25-24(26,27)17-5-7-18(8-6-17)29-23(32)28-11-2-12-30-13-10-21-20(15-30)19-4-1-3-16-9-14-31(21)22(16)19/h1,3-8,20-21H,2,9-15H2,(H2,28,29,32)/t20-,21-/m1/s1 RXLWYJYMHAUYSI-NHCUHLMSSA-N 50115078 1-[(6aR,10aS)-3-(4,5,7,8,10,10a-Hexahydro-6aH-pyrido[4,3-b]pyrrolo[3,2,1-hi]indol-9-yl)-propyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL440477 C-C chemokine receptor type 3 Homo sapiens 3700 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115078&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295487 104009066 CHEMBL440477 ZINC13443435 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208265 Fc1ccc(CC2CCN(CCCNC(=O)Nc3ccc(cc3)C#N)CC2)cc1 InChI=1S/C23H27FN4O/c24-21-6-2-18(3-7-21)16-19-10-14-28(15-11-19)13-1-12-26-23(29)27-22-8-4-20(17-25)5-9-22/h2-9,19H,1,10-16H2,(H2,26,27,29) PNUJVCPETLATLT-UHFFFAOYSA-N 50115079 1-(4-Cyano-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51286 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115079&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393469 104009067 CHEMBL51286 ZINC13443484 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208266 [O-][N+](=O)c1ccccc1NC(=O)NCCCN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C22H27FN4O3/c23-19-8-6-17(7-9-19)16-18-10-14-26(15-11-18)13-3-12-24-22(28)25-20-4-1-2-5-21(20)27(29)30/h1-2,4-9,18H,3,10-16H2,(H2,24,25,28) CXZLTHIWCQCTJV-UHFFFAOYSA-N 50115076 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(2-nitro-phenyl)-urea::CHEMBL50158 C-C chemokine receptor type 3 Homo sapiens 89 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115076&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295327 104009064 CHEMBL50158 ZINC13443496 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208267 COc1cccc(NC(=O)N2CCO[C@@H](CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H32FN3O3/c1-31-23-4-2-3-22(16-23)27-25(30)29-13-14-32-24(18-29)17-28-11-9-20(10-12-28)15-19-5-7-21(26)8-6-19/h2-8,16,20,24H,9-15,17-18H2,1H3,(H,27,30)/t24-/m0/s1 CBNWNPGNUKPULD-DEOSSOPVSA-N 50115077 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-morpholine-4-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL49117 C-C chemokine receptor type 3 Homo sapiens 260 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115077&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295433 104009065 CHEMBL49117 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208268 COc1cccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C23H31N3O2/c1-28-22-10-5-9-21(18-22)25-23(27)24-13-6-14-26-15-11-20(12-16-26)17-19-7-3-2-4-8-19/h2-5,7-10,18,20H,6,11-17H2,1H3,(H2,24,25,27) MOEVUYXPOZLPNN-UHFFFAOYSA-N 50115090 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-methoxy-phenyl)-urea::CHEMBL43666 C-C chemokine receptor type 3 Homo sapiens 300 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115090&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9951883 104009078 CHEMBL43666 ZINC13443451 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208270 CC(=O)c1cccc(NC(=O)NCCCN2CC[C@H](Cc3ccccc3)C[C@@H]2C(C)(O)O)c1 InChI=1S/C26H35N3O4/c1-19(30)22-10-6-11-23(18-22)28-25(31)27-13-7-14-29-15-12-21(17-24(29)26(2,32)33)16-20-8-4-3-5-9-20/h3-6,8-11,18,21,24,32-33H,7,12-17H2,1-2H3,(H2,27,28,31)/t21-,24-/m1/s1 NXVAVZFJAUFMKI-ZJSXRUAMSA-N 50115089 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-(1,1-dihydroxy-ethyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51244 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115089&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295641 104009077 CHEMBL51244 ZINC13443650 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208271 COc1cccc(NC(=O)N2CCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H32FN3O2/c1-31-24-4-2-3-23(16-24)27-25(30)29-14-11-21(18-29)17-28-12-9-20(10-13-28)15-19-5-7-22(26)8-6-19/h2-8,16,20-21H,9-15,17-18H2,1H3,(H,27,30) ZGWSSZLLOHMLII-UHFFFAOYSA-N 50115087 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-pyrrolidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL298414 C-C chemokine receptor type 3 Homo sapiens 240 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115087&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295479 104009075 CHEMBL298414 ZINC13443616 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208272 COc1cccc(NC(=O)N2CCCC(CCN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C27H36FN3O2/c1-33-26-6-2-5-25(19-26)29-27(32)31-14-3-4-23(20-31)13-17-30-15-11-22(12-16-30)18-21-7-9-24(28)10-8-21/h2,5-10,19,22-23H,3-4,11-18,20H2,1H3,(H,29,32) OXFKSXBVOROLRR-UHFFFAOYSA-N 50115088 3-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL51267 C-C chemokine receptor type 3 Homo sapiens 250 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115088&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295499 104009076 CHEMBL51267 ZINC13443605 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208273 CS(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C23H30FN3O2S/c1-30(29)22-5-2-4-21(17-22)26-23(28)25-12-3-13-27-14-10-19(11-15-27)16-18-6-8-20(24)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,25,26,28) FUVRNOAOLHLAAN-UHFFFAOYSA-N 50115091 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-methanesulfinyl-phenyl)-urea::CHEMBL50034 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115091&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295286 104009079 CHEMBL50034 ZINC13443519 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208274 COc1cccc(NC(=O)N2CCC(CC2)N2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C25H33N3O2/c1-30-24-9-5-8-22(19-24)26-25(29)28-16-12-23(13-17-28)27-14-10-21(11-15-27)18-20-6-3-2-4-7-20/h2-9,19,21,23H,10-18H2,1H3,(H,26,29) QETVEXKUAWMGHI-UHFFFAOYSA-N 50115092 4-Benzyl-[1,4']bipiperidinyl-1'-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL417547 C-C chemokine receptor type 3 Homo sapiens 2300 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115092&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295686 104009080 CHEMBL417547 ZINC13443577 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208276 COc1cccc(NC(=O)N2CCN(C(CN3CCC(Cc4ccc(F)cc4)CC3)C2)C(=O)OC(C)(C)C)c1 InChI=1S/C30H41FN4O4/c1-30(2,3)39-29(37)35-17-16-34(28(36)32-25-6-5-7-27(19-25)38-4)21-26(35)20-33-14-12-23(13-15-33)18-22-8-10-24(31)11-9-22/h5-11,19,23,26H,12-18,20-21H2,1-4H3,(H,32,36) BYJSSJUUKGUDHW-UHFFFAOYSA-N 50115081 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-(3-methoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL51937 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509693 104009069 CHEMBL51937 ZINC13443629 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208277 CSc1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C23H30FN3OS/c1-29-22-5-2-4-21(17-22)26-23(28)25-12-3-13-27-14-10-19(11-15-27)16-18-6-8-20(24)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,25,26,28) FQGDVQADZCRNHO-UHFFFAOYSA-N 50115093 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-methylsulfanyl-phenyl)-urea::CHEMBL50726 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115093&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295306 104009081 CHEMBL50726 ZINC13443512 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208278 COc1cccc(NC(=O)N2CCCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C26H34FN3O2/c1-32-25-6-2-5-24(17-25)28-26(31)30-13-3-4-22(19-30)18-29-14-11-21(12-15-29)16-20-7-9-23(27)10-8-20/h2,5-10,17,21-22H,3-4,11-16,18-19H2,1H3,(H,28,31) ONWGMJQANDWQQF-UHFFFAOYSA-N 50115082 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL50535 C-C chemokine receptor type 3 Homo sapiens 820.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295672 104009070 CHEMBL50535 ZINC13443592 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208279 CC(C)[C@@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C28H39N3O3/c1-20(2)27(33)26-18-23(17-22-9-5-4-6-10-22)13-16-31(26)15-8-14-29-28(34)30-25-12-7-11-24(19-25)21(3)32/h4-7,9-12,19-20,23,26-27,33H,8,13-18H2,1-3H3,(H2,29,30,34)/t23-,26-,27?/m1/s1 RRNALAYMXGNJNS-UTZIHYNGSA-N 50115094 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((R)-1-hydroxy-2-methyl-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL51815 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115094&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295567 104009082 CHEMBL51815 ZINC13443666 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212162 CNC(=O)c1ccc(NC(=O)Nc2cccc(c2)C(C)=O)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C30H33FN4O3/c1-20(36)23-4-3-5-27(18-23)33-30(38)34-28-11-8-24(29(37)32-2)17-25(28)19-35-14-12-22(13-15-35)16-21-6-9-26(31)10-7-21/h3-11,17-18,22H,12-16,19H2,1-2H3,(H,32,37)(H2,33,34,38) QIPAPFXTAOGTFK-UHFFFAOYSA-N 50117385 4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL127281 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117385&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10962347 104010941 CHEMBL127281 ZINC13475850 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212163 OC(CN1CCC(Cc2ccccc2)CC1)c1ccccc1NC(=O)Nc1ccccc1 InChI=1S/C27H31N3O2/c31-26(20-30-17-15-22(16-18-30)19-21-9-3-1-4-10-21)24-13-7-8-14-25(24)29-27(32)28-23-11-5-2-6-12-23/h1-14,22,26,31H,15-20H2,(H2,28,29,32) MDINXBRCQYXZRD-UHFFFAOYSA-N 50117384 1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-phenyl-urea::CHEMBL124206 C-C chemokine receptor type 3 Homo sapiens 249 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117384&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11732727 104010940 CHEMBL124206 ZINC13475776 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212164 C(CCc1ccccc1)CN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H29N/c1-3-9-20(10-4-1)11-7-8-16-23-17-14-22(15-18-23)19-21-12-5-2-6-13-21/h1-6,9-10,12-13,22H,7-8,11,14-19H2 JWQSCIOWKPWNLB-UHFFFAOYSA-N 50034212 4-Benzyl-1-(4-phenyl-butyl)-piperidine::CHEMBL276784 C-C chemokine receptor type 3 Homo sapiens 3800 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034212&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11722772 103942422 CHEMBL276784 ZINC13475727 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212166 O=C(Nc1cccc(CN2CCC(Cc3ccccc3)CC2)c1)Nc1ccc2[nH]ncc2c1 InChI=1S/C27H29N5O/c33-27(30-25-9-10-26-23(17-25)18-28-31-26)29-24-8-4-7-22(16-24)19-32-13-11-21(12-14-32)15-20-5-2-1-3-6-20/h1-10,16-18,21H,11-15,19H2,(H,28,31)(H2,29,30,33) VHWQFOSMMBMAQY-UHFFFAOYSA-N 50117383 1-[3-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-5-yl)-urea::CHEMBL124748 C-C chemokine receptor type 3 Homo sapiens 620 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117383&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11004681 104010939 CHEMBL124748 ZINC13475773 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212167 CC(C)(C)NC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C33H42ClN3O2/c1-31(2,3)36-30(38)35-25-32(26-11-6-4-7-12-26,27-13-8-5-9-14-27)19-10-22-37-23-20-33(39,21-24-37)28-15-17-29(34)18-16-28/h4-9,11-18,39H,10,19-25H2,1-3H3,(H2,35,36,38) IQAOPXDQHGLJKW-UHFFFAOYSA-N 50117386 1-tert-Butyl-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea::CHEMBL435812 C-C chemokine receptor type 3 Homo sapiens 3000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117386&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11734303 104010942 CHEMBL435812 ZINC27298332 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212168 COC(=O)c1cccc(NC(=O)Nc2ccccc2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C28H30FN3O3/c1-35-27(33)24-8-5-9-26(31-28(34)30-23-6-3-2-4-7-23)25(24)19-32-16-14-21(15-17-32)18-20-10-12-22(29)13-11-20/h2-13,21H,14-19H2,1H3,(H2,30,31,34) IYAXVOVEBDKYET-UHFFFAOYSA-N 50117387 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-(3-phenyl-ureido)-benzoic acid methyl ester::CHEMBL413113 C-C chemokine receptor type 3 Homo sapiens 9.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117387&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10939698 104010943 CHEMBL413113 ZINC13475851 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212170 COC(=O)c1cccc(NC(=O)Nc2cccc(c2)C#N)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C29H29FN4O3/c1-37-28(35)25-6-3-7-27(33-29(36)32-24-5-2-4-22(17-24)18-31)26(25)19-34-14-12-21(13-15-34)16-20-8-10-23(30)11-9-20/h2-11,17,21H,12-16,19H2,1H3,(H2,32,33,36) TYMFMCIPPKNHMM-UHFFFAOYSA-N 50117389 3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester::CHEMBL124628 C-C chemokine receptor type 3 Homo sapiens 7.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117389&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10874762 104010945 CHEMBL124628 ZINC13475853 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212171 CNC(=O)c1cccc(NC(=O)Nc2ccccc2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C28H31FN4O2/c1-30-27(34)24-8-5-9-26(32-28(35)31-23-6-3-2-4-7-23)25(24)19-33-16-14-21(15-17-33)18-20-10-12-22(29)13-11-20/h2-13,21H,14-19H2,1H3,(H,30,34)(H2,31,32,35) HHTCJTLVUIKPEK-UHFFFAOYSA-N 50117392 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-3-(3-phenyl-ureido)-benzamide::CHEMBL123837 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117392&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11762511 104010948 CHEMBL123837 ZINC13475865 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212172 O=C(NCc1ccc2OCOc2c1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C28H31N3O3/c32-28(29-18-23-10-11-26-27(17-23)34-20-33-26)30-25-9-5-4-8-24(25)19-31-14-12-22(13-15-31)16-21-6-2-1-3-7-21/h1-11,17,22H,12-16,18-20H2,(H2,29,30,32) ZJMRSKLYKCUCRF-UHFFFAOYSA-N 50117394 1-Benzo[1,3]dioxol-5-ylmethyl-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL445379 C-C chemokine receptor type 3 Homo sapiens 1750 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117394&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10874167 104010950 CHEMBL445379 ZINC13475789 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212173 O=C(NCc1ccc2OCOc2c1)Nc1ccccc1CN1CCC(CC1)C(=O)c1ccccc1 InChI=1S/C28H29N3O4/c32-27(21-6-2-1-3-7-21)22-12-14-31(15-13-22)18-23-8-4-5-9-24(23)30-28(33)29-17-20-10-11-25-26(16-20)35-19-34-25/h1-11,16,22H,12-15,17-19H2,(H2,29,30,33) RGQULMBULIGJHL-UHFFFAOYSA-N 50117395 1-Benzo[1,3]dioxol-5-ylmethyl-3-[2-(4-benzoyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL124336 C-C chemokine receptor type 3 Homo sapiens 7350 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117395&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11812728 104010951 CHEMBL124336 ZINC13475791 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212174 CC(=O)c1cccc(NC(=O)Nc2cc3OCOc3cc2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C29H31N3O4/c1-20(33)23-8-5-9-25(15-23)30-29(34)31-26-17-28-27(35-19-36-28)16-24(26)18-32-12-10-22(11-13-32)14-21-6-3-2-4-7-21/h2-9,15-17,22H,10-14,18-19H2,1H3,(H2,30,31,34) MQFKNRIMMUANLC-UHFFFAOYSA-N 50117396 1-(3-Acetyl-phenyl)-3-[6-(4-benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-urea::CHEMBL124272 C-C chemokine receptor type 3 Homo sapiens 228 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117396&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11730610 104010952 CHEMBL124272 ZINC13475827 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212175 OC1(CCN(CCCC(CNC(=O)NCCc2ccc(F)cc2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C37H41ClFN3O2/c38-33-16-14-32(15-17-33)37(44)22-26-42(27-23-37)25-7-21-36(30-8-3-1-4-9-30,31-10-5-2-6-11-31)28-41-35(43)40-24-20-29-12-18-34(39)19-13-29/h1-6,8-19,44H,7,20-28H2,(H2,40,41,43) GFNXQKRIPFSWCM-UHFFFAOYSA-N 50117397 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-[2-(4-fluoro-phenyl)-ethyl]-urea::CHEMBL333422 C-C chemokine receptor type 3 Homo sapiens 2200 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117397&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11828215 104010953 CHEMBL333422 ZINC27212855 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212176 OC1(CCN(CCCC(CNC(=O)Nc2cccc(c2)C(F)(F)F)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C36H37ClF3N3O2/c37-31-17-15-29(16-18-31)35(45)20-23-43(24-21-35)22-8-19-34(27-9-3-1-4-10-27,28-11-5-2-6-12-28)26-41-33(44)42-32-14-7-13-30(25-32)36(38,39)40/h1-7,9-18,25,45H,8,19-24,26H2,(H2,41,42,44) BRPKVWBIDATEPI-UHFFFAOYSA-N 50117398 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(3-trifluoromethyl-phenyl)-urea::CHEMBL338624 C-C chemokine receptor type 3 Homo sapiens 19300 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117398&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11814253 104010954 CHEMBL338624 ZINC27298420 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212177 COC(=O)N1CCC(CC1)NC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C36H45ClN4O4/c1-45-34(43)41-23-17-32(18-24-41)39-33(42)38-27-35(28-9-4-2-5-10-28,29-11-6-3-7-12-29)19-8-22-40-25-20-36(44,21-26-40)30-13-15-31(37)16-14-30/h2-7,9-16,32,44H,8,17-27H2,1H3,(H2,38,39,42) QNHKVEUPGHSYFU-UHFFFAOYSA-N 50117390 4-(3-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-ureido)-piperidine-1-carboxylic acid methyl ester::CHEMBL124585 C-C chemokine receptor type 3 Homo sapiens 5300 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117390&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11072275 104010946 CHEMBL124585 ZINC27214557 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212179 OCCCCNC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C33H42ClN3O3/c34-30-16-14-29(15-17-30)33(40)19-23-37(24-20-33)22-9-18-32(27-10-3-1-4-11-27,28-12-5-2-6-13-28)26-36-31(39)35-21-7-8-25-38/h1-6,10-17,38,40H,7-9,18-26H2,(H2,35,36,39) XKODNICTPMTYQO-UHFFFAOYSA-N 50117400 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-hydroxy-butyl)-urea::CHEMBL126978 C-C chemokine receptor type 3 Homo sapiens 5950 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117400&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10995329 104010956 CHEMBL126978 ZINC27298677 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212180 CC(=O)c1cccc(NC(=O)Nc2cc3OCOc3cc2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C29H30FN3O4/c1-19(34)22-3-2-4-25(14-22)31-29(35)32-26-16-28-27(36-18-37-28)15-23(26)17-33-11-9-21(10-12-33)13-20-5-7-24(30)8-6-20/h2-8,14-16,21H,9-13,17-18H2,1H3,(H2,31,32,35) NDXPXQWBWHPZBF-UHFFFAOYSA-N 50117401 1-(3-Acetyl-phenyl)-3-{6-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-urea::CHEMBL337990 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117401&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10029075 104010957 CHEMBL337990 ZINC13475834 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212181 OC1(CCN(CCCC(CNC(=O)NCC2CCCCC2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C36H46ClN3O2/c37-33-19-17-32(18-20-33)36(42)22-25-40(26-23-36)24-10-21-35(30-13-6-2-7-14-30,31-15-8-3-9-16-31)28-39-34(41)38-27-29-11-4-1-5-12-29/h2-3,6-9,13-20,29,42H,1,4-5,10-12,21-28H2,(H2,38,39,41) JQAMPRHNZFBEDN-UHFFFAOYSA-N 50117402 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-cyclohexylmethyl-urea::CHEMBL341306 C-C chemokine receptor type 3 Homo sapiens 2400 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117402&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11124782 104010958 CHEMBL341306 ZINC27210061 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212185 COC(=O)c1cccc(NC(=O)Nc2cccc(OC)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C29H32FN3O4/c1-36-24-6-3-5-23(18-24)31-29(35)32-27-8-4-7-25(28(34)37-2)26(27)19-33-15-13-21(14-16-33)17-20-9-11-22(30)12-10-20/h3-12,18,21H,13-17,19H2,1-2H3,(H2,31,32,35) ICPQEPFVLYMWML-UHFFFAOYSA-N 50117403 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester::CHEMBL124821 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117403&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10983981 104010959 CHEMBL124821 ZINC13475855 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212188 [I-].C[N+]1(Cc2cc3OCOc3cc2NC(=O)Nc2cccc(c2)C#N)CCC(Cc2ccccc2)CC1 InChI=1S/C29H30N4O3.HI/c1-33(12-10-22(11-13-33)14-21-6-3-2-4-7-21)19-24-16-27-28(36-20-35-27)17-26(24)32-29(34)31-25-9-5-8-23(15-25)18-30;/h2-9,15-17,22H,10-14,19-20H2,1H3,(H-,31,32,34);1H ZZNIUCGWZFSFNF-UHFFFAOYSA-N 50117411 4-Benzyl-1-{6-[3-(3-cyano-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-1-methyl-piperidinium; iodide::CHEMBL123616 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117411&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11006581 104010967 CHEMBL123616 ZINC13475869 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212190 Fc1ccc(CCNC(=O)Nc2ccccc2CN2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C27H31FN4O/c28-25-12-10-22(11-13-25)14-15-29-27(33)30-26-9-5-4-8-24(26)21-32-18-16-31(17-19-32)20-23-6-2-1-3-7-23/h1-13H,14-21H2,(H2,29,30,33) MOMUBAOCDLVZRF-UHFFFAOYSA-N 50117408 1-[2-(4-Benzyl-piperazin-1-ylmethyl)-phenyl]-3-[2-(4-fluoro-phenyl)-ethyl]-urea::CHEMBL125220 C-C chemokine receptor type 3 Homo sapiens 9200.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117408&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11762084 104010964 CHEMBL125220 ZINC22925905 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212191 COc1cccc(NC(=O)Nc2ccc(CO)cc2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H32FN3O3/c1-35-26-4-2-3-25(17-26)30-28(34)31-27-10-7-22(19-33)16-23(27)18-32-13-11-21(12-14-32)15-20-5-8-24(29)9-6-20/h2-10,16-17,21,33H,11-15,18-19H2,1H3,(H2,30,31,34) DWMDOQUSAMOMIZ-UHFFFAOYSA-N 50117407 1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-hydroxymethyl-phenyl}-3-(3-methoxy-phenyl)-urea::CHEMBL126220 C-C chemokine receptor type 3 Homo sapiens 47 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117407&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10906911 104010963 CHEMBL126220 ZINC13475844 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212192 CC(=O)c1cccc(NC(=O)Nc2ccccc2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H30FN3O2/c1-20(33)23-6-4-7-26(18-23)30-28(34)31-27-8-3-2-5-24(27)19-32-15-13-22(14-16-32)17-21-9-11-25(29)12-10-21/h2-12,18,22H,13-17,19H2,1H3,(H2,30,31,34) GFGVSPYXQBYZOT-UHFFFAOYSA-N 50117413 1-(3-Acetyl-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-urea::CHEMBL124317 C-C chemokine receptor type 3 Homo sapiens 125 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117413&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11037869 104010969 CHEMBL124317 ZINC13475799 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212194 O=C(Nc1cccc(c1)C#N)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C27H28N4O/c28-19-23-9-6-11-25(18-23)29-27(32)30-26-12-5-4-10-24(26)20-31-15-13-22(14-16-31)17-21-7-2-1-3-8-21/h1-12,18,22H,13-17,20H2,(H2,29,30,32) RCGRXJAFIJOAFV-UHFFFAOYSA-N 50117415 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-cyano-phenyl)-urea::CHEMBL123791 C-C chemokine receptor type 3 Homo sapiens 750 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117415&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11069916 104010971 CHEMBL123791 ZINC13475748 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212195 COc1cccc(NC(=O)Nc2cc3OCOc3cc2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H30FN3O4/c1-34-24-4-2-3-23(15-24)30-28(33)31-25-16-27-26(35-18-36-27)14-21(25)17-32-11-9-20(10-12-32)13-19-5-7-22(29)8-6-19/h2-8,14-16,20H,9-13,17-18H2,1H3,(H2,30,31,33) HWJJZMUNJJXTRC-UHFFFAOYSA-N 50117417 1-{6-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-3-(3-methoxy-phenyl)-urea::CHEMBL123580 C-C chemokine receptor type 3 Homo sapiens 141 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117417&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10917990 104010973 CHEMBL123580 ZINC13475836 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212196 COC(=O)c1ccc(NC(=O)Nc2cccc(c2)C#N)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C29H29FN4O3/c1-37-28(35)23-7-10-27(33-29(36)32-26-4-2-3-22(16-26)18-31)24(17-23)19-34-13-11-21(12-14-34)15-20-5-8-25(30)9-6-20/h2-10,16-17,21H,11-15,19H2,1H3,(H2,32,33,36) ARWPPVOVOQJACY-UHFFFAOYSA-N 50117416 4-[3-(3-Cyano-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester::CHEMBL126163 C-C chemokine receptor type 3 Homo sapiens 67 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117416&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10929194 104010972 CHEMBL126163 ZINC13475837 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212197 O=C1CC2(CCc3ccccc23)C(=O)N1CC1CCN(CCc2ccccc2)CC1 InChI=1S/C26H30N2O2/c29-24-18-26(14-10-22-8-4-5-9-23(22)26)25(30)28(24)19-21-12-16-27(17-13-21)15-11-20-6-2-1-3-7-20/h1-9,21H,10-19H2 OKBDKGHBTXQPPP-UHFFFAOYSA-N 50117418 1'-(1-phenethylhexahydro-4-pyridinylmethyl)spiro[2,3-dihydro-1H-indene-1,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione::CHEMBL341144 C-C chemokine receptor type 3 Homo sapiens 2000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117418&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44349614 104010974 CHEMBL341144 ZINC13475707 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212199 O=C(NCC(c1ccccc1)c1ccccc1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C34H37N3O/c38-34(35-25-32(29-14-6-2-7-15-29)30-16-8-3-9-17-30)36-33-19-11-10-18-31(33)26-37-22-20-28(21-23-37)24-27-12-4-1-5-13-27/h1-19,28,32H,20-26H2,(H2,35,36,38) IPYSGZQQGUWCKZ-UHFFFAOYSA-N 50117419 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,2-diphenyl-ethyl)-urea::CHEMBL123807 C-C chemokine receptor type 3 Homo sapiens 2650 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117419&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11762865 104010975 CHEMBL123807 ZINC03976302 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212200 OC1(CCN(CCCC(CNC(=O)Nc2ccccc2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C35H38ClN3O2/c36-31-19-17-30(18-20-31)35(41)22-25-39(26-23-35)24-10-21-34(28-11-4-1-5-12-28,29-13-6-2-7-14-29)27-37-33(40)38-32-15-8-3-9-16-32/h1-9,11-20,41H,10,21-27H2,(H2,37,38,40) YWPRMGZYWMCDAA-UHFFFAOYSA-N 50117422 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-phenyl-urea::CHEMBL125618 C-C chemokine receptor type 3 Homo sapiens 9800.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117422&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11060814 104010978 CHEMBL125618 ZINC27210057 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212201 OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccccc1NC(=O)Nc1cccc(c1)C#N InChI=1S/C28H29FN4O2/c29-23-10-8-20(9-11-23)16-21-12-14-33(15-13-21)19-27(34)25-6-1-2-7-26(25)32-28(35)31-24-5-3-4-22(17-24)18-30/h1-11,17,21,27,34H,12-16,19H2,(H2,31,32,35) RAJQVVGUPOWQBU-UHFFFAOYSA-N 50117421 1-(3-Cyano-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-urea::CHEMBL124438 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117421&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11059789 104010977 CHEMBL124438 ZINC13475807 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212202 COC(=O)c1ccc(NC(=O)Nc2cccc(c2)C(C)=O)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C30H32FN3O4/c1-20(35)23-4-3-5-27(18-23)32-30(37)33-28-11-8-24(29(36)38-2)17-25(28)19-34-14-12-22(13-15-34)16-21-6-9-26(31)10-7-21/h3-11,17-18,22H,12-16,19H2,1-2H3,(H2,32,33,37) HVDRJOSWHPOEEN-UHFFFAOYSA-N 50117420 4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester::CHEMBL125012 C-C chemokine receptor type 3 Homo sapiens 42 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117420&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10864223 104010976 CHEMBL125012 ZINC13475839 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212205 N#CC(CCCN1CCC(Cc2ccccc2)CC1)(c1ccccc1)c1ccccc1 InChI=1S/C29H32N2/c30-24-29(27-13-6-2-7-14-27,28-15-8-3-9-16-28)19-10-20-31-21-17-26(18-22-31)23-25-11-4-1-5-12-25/h1-9,11-16,26H,10,17-23H2 SMPJXLOBQLJHRN-UHFFFAOYSA-N 50117425 5-(4-Benzyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile::CHEMBL127395 C-C chemokine receptor type 3 Homo sapiens 4600 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117425&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10916572 104010981 CHEMBL127395 ZINC13475723 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212207 OCc1cccc(NC(=O)Nc2ccccc2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C27H30FN3O2/c28-23-11-9-20(10-12-23)17-21-13-15-31(16-14-21)18-25-22(19-32)5-4-8-26(25)30-27(33)29-24-6-2-1-3-7-24/h1-12,21,32H,13-19H2,(H2,29,30,33) ONPWEDRTDHCKDY-UHFFFAOYSA-N 50117427 1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-hydroxymethyl-phenyl}-3-phenyl-urea::CHEMBL126218 C-C chemokine receptor type 3 Homo sapiens 53.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117427&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11004826 104010983 CHEMBL126218 ZINC13475859 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212208 COC(=O)c1ccc(NC(=O)Nc2cccc(OC)c2)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C29H32FN3O4/c1-36-26-5-3-4-25(18-26)31-29(35)32-27-11-8-22(28(34)37-2)17-23(27)19-33-14-12-21(13-15-33)16-20-6-9-24(30)10-7-20/h3-11,17-18,21H,12-16,19H2,1-2H3,(H2,31,32,35) AZNIXHOAQCCYOH-UHFFFAOYSA-N 50117428 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester::CHEMBL126520 C-C chemokine receptor type 3 Homo sapiens 64 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117428&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10983980 104010984 CHEMBL126520 ZINC13475838 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212209 Fc1ccc(CC2CCN(Cc3ccccc3NC(=O)Nc3ccccc3)CC2)cc1 InChI=1S/C26H28FN3O/c27-23-12-10-20(11-13-23)18-21-14-16-30(17-15-21)19-22-6-4-5-9-25(22)29-26(31)28-24-7-2-1-3-8-24/h1-13,21H,14-19H2,(H2,28,29,31) TZAOOVVJBARAQB-UHFFFAOYSA-N 50117432 1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-3-phenyl-urea::CHEMBL124669 C-C chemokine receptor type 3 Homo sapiens 361 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117432&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11112528 104010988 CHEMBL124669 ZINC13475796 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212210 Fc1ccc(CCNC(=O)Nc2ccccc2CN2CCC(Cc3ccccc3)CC2)cc1 InChI=1S/C28H32FN3O/c29-26-12-10-22(11-13-26)14-17-30-28(33)31-27-9-5-4-8-25(27)21-32-18-15-24(16-19-32)20-23-6-2-1-3-7-23/h1-13,24H,14-21H2,(H2,30,31,33) HRTGCUFRXTWMCL-UHFFFAOYSA-N 50117429 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-[2-(4-fluoro-phenyl)-ethyl]-urea::CHEMBL125167 C-C chemokine receptor type 3 Homo sapiens 3800 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117429&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10939210 104010985 CHEMBL125167 ZINC13475787 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212211 OC1(CCN(CCCC(CNC(=O)NCCN2CCCCC2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C36H47ClN4O2/c37-33-17-15-32(16-18-33)36(43)20-26-41(27-21-36)25-10-19-35(30-11-4-1-5-12-30,31-13-6-2-7-14-31)29-39-34(42)38-22-28-40-23-8-3-9-24-40/h1-2,4-7,11-18,43H,3,8-10,19-29H2,(H2,38,39,42) XAWMVBRRSKLCED-UHFFFAOYSA-N 50117431 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2-piperidin-1-yl-ethyl)-urea::CHEMBL339752 C-C chemokine receptor type 3 Homo sapiens 2200 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117431&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11104005 104010987 CHEMBL339752 ZINC27298671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212212 O=C(Nc1cccc(c1)C#N)Nc1ccccc1CCN1CCC(Cc2ccccc2)CC1 InChI=1S/C28H30N4O/c29-21-24-9-6-11-26(20-24)30-28(33)31-27-12-5-4-10-25(27)15-18-32-16-13-23(14-17-32)19-22-7-2-1-3-8-22/h1-12,20,23H,13-19H2,(H2,30,31,33) YSFKPULSVDIJEL-UHFFFAOYSA-N 50117433 1-{2-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenyl}-3-(3-cyano-phenyl)-urea::CHEMBL340080 C-C chemokine receptor type 3 Homo sapiens 140 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117433&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11004663 104010989 CHEMBL340080 ZINC13475754 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212215 O=C(NCc1ccccc1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C27H31N3O/c31-27(28-20-24-11-5-2-6-12-24)29-26-14-8-7-13-25(26)21-30-17-15-23(16-18-30)19-22-9-3-1-4-10-22/h1-14,23H,15-21H2,(H2,28,29,31) WBKAFJHGIOLOIL-UHFFFAOYSA-N 50117434 1-Benzyl-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL124321 C-C chemokine receptor type 3 Homo sapiens 3400 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117434&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11133428 104010990 CHEMBL124321 ZINC13475738 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212216 OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccccc1NC(=O)Nc1ccccc1 InChI=1S/C27H30FN3O2/c28-22-12-10-20(11-13-22)18-21-14-16-31(17-15-21)19-26(32)24-8-4-5-9-25(24)30-27(33)29-23-6-2-1-3-7-23/h1-13,21,26,32H,14-19H2,(H2,29,30,33) VXKVMPBIMSJSTA-UHFFFAOYSA-N 50117438 1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-3-phenyl-urea::CHEMBL446164 C-C chemokine receptor type 3 Homo sapiens 24 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117438&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10863252 104010994 CHEMBL446164 ZINC13475801 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212217 OCc1ccc(NC(=O)Nc2cccc(c2)C#N)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H29FN4O2/c29-25-7-4-20(5-8-25)14-21-10-12-33(13-11-21)18-24-15-23(19-34)6-9-27(24)32-28(35)31-26-3-1-2-22(16-26)17-30/h1-9,15-16,21,34H,10-14,18-19H2,(H2,31,32,35) JRYQAIOBAPWOAW-UHFFFAOYSA-N 50117435 1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-4-hydroxymethyl-phenyl}-urea::CHEMBL125884 C-C chemokine receptor type 3 Homo sapiens 55.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117435&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10928826 104010991 CHEMBL125884 ZINC13475841 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212218 OCCCNC(=O)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H31N3O2/c27-16-6-13-24-23(28)25-22-10-5-4-9-21(22)18-26-14-11-20(12-15-26)17-19-7-2-1-3-8-19/h1-5,7-10,20,27H,6,11-18H2,(H2,24,25,28) OXWRFVHWXRBUFE-UHFFFAOYSA-N 50117436 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-hydroxy-propyl)-urea::CHEMBL125026 C-C chemokine receptor type 3 Homo sapiens 2600 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117436&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11825113 104010992 CHEMBL125026 ZINC13475735 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212219 Fc1ccc(F)c(NC(=O)Nc2ccccc2CN2CCC(CC2)c2ccccc2)c1 InChI=1S/C25H25F2N3O/c26-21-10-11-22(27)24(16-21)29-25(31)28-23-9-5-4-8-20(23)17-30-14-12-19(13-15-30)18-6-2-1-3-7-18/h1-11,16,19H,12-15,17H2,(H2,28,29,31) RCQSDHOSNSDSFS-UHFFFAOYSA-N 50117437 1-(2,5-Difluoro-phenyl)-3-[2-(4-phenyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL331530 C-C chemokine receptor type 3 Homo sapiens 11000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117437&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11101888 104010993 CHEMBL331530 ZINC13475782 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212221 COc1cccc(NC(=O)Nc2ccccc2CCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H32FN3O2/c1-34-26-7-4-6-25(20-26)30-28(33)31-27-8-3-2-5-23(27)15-18-32-16-13-22(14-17-32)19-21-9-11-24(29)12-10-21/h2-12,20,22H,13-19H2,1H3,(H2,30,31,33) GZGYCEIWHWDLON-UHFFFAOYSA-N 50117439 1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-3-(3-methoxy-phenyl)-urea::CHEMBL341074 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117439&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10895831 104010995 CHEMBL341074 ZINC13475811 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212223 O=C(NCCN1CCCCC1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C27H38N4O/c32-27(28-15-20-30-16-7-2-8-17-30)29-26-12-6-5-11-25(26)22-31-18-13-24(14-19-31)21-23-9-3-1-4-10-23/h1,3-6,9-12,24H,2,7-8,13-22H2,(H2,28,29,32) VGQGKHAETPMUNJ-UHFFFAOYSA-N 50117424 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2-piperidin-1-yl-ethyl)-urea::CHEMBL125325 C-C chemokine receptor type 3 Homo sapiens 7600 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117424&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11026461 104010980 CHEMBL125325 ZINC13475733 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212224 COC(=O)c1ccc(CN2CCC(Cc3ccccc3)CC2)c(NC(=O)Nc2cccc(OC)c2)c1 InChI=1S/C29H33N3O4/c1-35-26-10-6-9-25(19-26)30-29(34)31-27-18-23(28(33)36-2)11-12-24(27)20-32-15-13-22(14-16-32)17-21-7-4-3-5-8-21/h3-12,18-19,22H,13-17,20H2,1-2H3,(H2,30,31,34) MICNQVZTKFBIMO-UHFFFAOYSA-N 50117440 4-(4-Benzyl-piperidin-1-ylmethyl)-3-[3-(3-methoxy-phenyl)-ureido]-benzoic acid methyl ester::CHEMBL434437 C-C chemokine receptor type 3 Homo sapiens 777.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117440&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11005432 104010996 CHEMBL434437 ZINC13475817 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212225 O=C(Nc1cccc(c1)C#N)Nc1cc2OCOc2cc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C28H28N4O3/c29-17-22-7-4-8-24(14-22)30-28(33)31-25-16-27-26(34-19-35-27)15-23(25)18-32-11-9-21(10-12-32)13-20-5-2-1-3-6-20/h1-8,14-16,21H,9-13,18-19H2,(H2,30,31,33) SUPPNJZTOAKITB-UHFFFAOYSA-N 50117443 1-[6-(4-Benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-3-(3-cyano-phenyl)-urea::CHEMBL123962 C-C chemokine receptor type 3 Homo sapiens 237 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117443&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9982077 104010999 CHEMBL123962 ZINC13475830 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212226 O=C(NC1CCN(Cc2ccccc2)CC1)Nc1cccc(CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C32H40N4O/c37-32(33-30-16-20-36(21-17-30)24-28-10-5-2-6-11-28)34-31-13-7-12-29(23-31)25-35-18-14-27(15-19-35)22-26-8-3-1-4-9-26/h1-13,23,27,30H,14-22,24-25H2,(H2,33,34,37) QACIWFUOGVFMLP-UHFFFAOYSA-N 50117444 1-(1-Benzyl-piperidin-4-yl)-3-[3-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL332227 C-C chemokine receptor type 3 Homo sapiens 3700 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11145481 104011000 CHEMBL332227 ZINC13475766 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212227 OC(CN1CCC(Cc2ccccc2)CC1)c1ccccc1NC(=O)Nc1cccc(c1)C#N InChI=1S/C28H30N4O2/c29-19-23-9-6-10-24(18-23)30-28(34)31-26-12-5-4-11-25(26)27(33)20-32-15-13-22(14-16-32)17-21-7-2-1-3-8-21/h1-12,18,22,27,33H,13-17,20H2,(H2,30,31,34) OWMOPGNTGWYVRD-UHFFFAOYSA-N 50117442 1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(3-cyano-phenyl)-urea::CHEMBL125132 C-C chemokine receptor type 3 Homo sapiens 49 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117442&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11733139 104010998 CHEMBL125132 ZINC13475764 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212229 O=C(NC1CCN(Cc2ccccc2)CC1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C32H40N4O/c37-32(33-30-17-21-35(22-18-30)24-28-11-5-2-6-12-28)34-31-14-8-7-13-29(31)25-36-19-15-27(16-20-36)23-26-9-3-1-4-10-26/h1-14,27,30H,15-25H2,(H2,33,34,37) WQBJUUITOQERMR-UHFFFAOYSA-N 50117441 1-(1-Benzyl-piperidin-4-yl)-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea::CHEMBL125108 C-C chemokine receptor type 3 Homo sapiens 3900 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117441&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9935588 104010997 CHEMBL125108 ZINC00602669 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212230 O=C(Nc1ccc2[nH]ncc2c1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C27H29N5O/c33-27(29-24-10-11-26-23(17-24)18-28-31-26)30-25-9-5-4-8-22(25)19-32-14-12-21(13-15-32)16-20-6-2-1-3-7-20/h1-11,17-18,21H,12-16,19H2,(H,28,31)(H2,29,30,33) HOSIRHWCFKBJCG-UHFFFAOYSA-N 50117414 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-5-yl)-urea::CHEMBL124390 C-C chemokine receptor type 3 Homo sapiens 450 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117414&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11048445 104010970 CHEMBL124390 ZINC13475750 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212231 COc1cccc(NC(=O)Nc2ccccc2CCN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C28H33N3O2/c1-33-26-12-7-11-25(21-26)29-28(32)30-27-13-6-5-10-24(27)16-19-31-17-14-23(15-18-31)20-22-8-3-2-4-9-22/h2-13,21,23H,14-20H2,1H3,(H2,29,30,32) RAAYIXGRKXEPIO-UHFFFAOYSA-N 50117426 1-{2-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-phenyl}-3-(3-methoxy-phenyl)-urea::CHEMBL331634 C-C chemokine receptor type 3 Homo sapiens 180 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117426&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11026634 104010982 CHEMBL331634 ZINC13475756 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212232 OC1(CCN(CCCC(CNC(=O)NCc2ccccc2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C36H40ClN3O2/c37-33-19-17-32(18-20-33)36(42)22-25-40(26-23-36)24-10-21-35(30-13-6-2-7-14-30,31-15-8-3-9-16-31)28-39-34(41)38-27-29-11-4-1-5-12-29/h1-9,11-20,42H,10,21-28H2,(H2,38,39,41) XRQUMBICQIZGDT-UHFFFAOYSA-N 50117410 1-Benzyl-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea::CHEMBL125753 C-C chemokine receptor type 3 Homo sapiens 8300.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117410&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11828013 104010966 CHEMBL125753 ZINC27210065 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212234 COc1cccc(NC(=O)Nc2ccccc2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C27H31N3O2/c1-32-25-12-7-11-24(19-25)28-27(31)29-26-13-6-5-10-23(26)20-30-16-14-22(15-17-30)18-21-8-3-2-4-9-21/h2-13,19,22H,14-18,20H2,1H3,(H2,28,29,31) QTOZBBZMQKESRV-UHFFFAOYSA-N 50117446 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-methoxy-phenyl)-urea::CHEMBL123511 C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117446&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11026367 104011002 CHEMBL123511 ZINC13475744 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212235 COC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(C)=O)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C30H32FN3O4/c1-20(35)23-5-3-6-25(18-23)32-30(37)33-28-8-4-7-26(29(36)38-2)27(28)19-34-15-13-22(14-16-34)17-21-9-11-24(31)12-10-21/h3-12,18,22H,13-17,19H2,1-2H3,(H2,32,33,37) QPKZYMPVZYOAII-UHFFFAOYSA-N 50117447 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester::CHEMBL441656 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11763035 104011003 CHEMBL441656 ZINC13475857 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212239 NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C#N)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C28H28FN5O2/c29-22-9-7-19(8-10-22)15-20-11-13-34(14-12-20)18-25-24(27(31)35)5-2-6-26(25)33-28(36)32-23-4-1-3-21(16-23)17-30/h1-10,16,20H,11-15,18H2,(H2,31,35)(H2,32,33,36) PKLRWKZFOAMODS-UHFFFAOYSA-N 50117451 3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide::CHEMBL411956 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11733617 104011007 CHEMBL411956 ZINC13475862 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212241 C(CCc1ccccc1)CN1CCN(Cc2ccccc2)CC1 InChI=1S/C21H28N2/c1-3-9-20(10-4-1)11-7-8-14-22-15-17-23(18-16-22)19-21-12-5-2-6-13-21/h1-6,9-10,12-13H,7-8,11,14-19H2 XYAJNJRPRCIANT-UHFFFAOYSA-N 50034204 1-Benzyl-4-(4-phenyl-butyl)-piperazine::CHEMBL19375 C-C chemokine receptor type 3 Homo sapiens 8400 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034204&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9972570 103942414 CHEMBL19375 ZINC22925894 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212243 CC1N(CC2CCN(CCc3ccccc3)CC2)C(=O)C2=C1CC=CC2 InChI=1S/C23H30N2O/c1-18-21-9-5-6-10-22(21)23(26)25(18)17-20-12-15-24(16-13-20)14-11-19-7-3-2-4-8-19/h2-8,18,20H,9-17H2,1H3 GFEHKHWLVNFFRC-UHFFFAOYSA-N 50117449 3-Methyl-2-(1-phenethyl-piperidin-4-ylmethyl)-2,3,4,7-tetrahydro-isoindol-1-one::CHEMBL125643 C-C chemokine receptor type 3 Homo sapiens 12000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117449&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44349204 104011005 CHEMBL125643 ZINC13475703 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212244 CC(C)NC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C32H40ClN3O2/c1-25(2)35-30(37)34-24-31(26-10-5-3-6-11-26,27-12-7-4-8-13-27)18-9-21-36-22-19-32(38,20-23-36)28-14-16-29(33)17-15-28/h3-8,10-17,25,38H,9,18-24H2,1-2H3,(H2,34,35,37) BKEFXMVWRHAVTF-UHFFFAOYSA-N 50117409 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-isopropyl-urea::CHEMBL123622 C-C chemokine receptor type 3 Homo sapiens 6100 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117409&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11060510 104010965 CHEMBL123622 ZINC13475715 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212245 CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C#N)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C29H30FN5O2/c1-32-28(36)25-6-3-7-27(34-29(37)33-24-5-2-4-22(17-24)18-31)26(25)19-35-14-12-21(13-15-35)16-20-8-10-23(30)11-9-20/h2-11,17,21H,12-16,19H2,1H3,(H,32,36)(H2,33,34,37) YXOROSQPTDHFJJ-UHFFFAOYSA-N 50117393 3-[3-(3-Cyano-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL337962 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117393&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11730796 104010949 CHEMBL337962 ZINC00588830 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212246 CC(=O)c1cccc(NC(=O)Nc2ccccc2CCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C29H32FN3O2/c1-21(34)25-6-4-7-27(20-25)31-29(35)32-28-8-3-2-5-24(28)15-18-33-16-13-23(14-17-33)19-22-9-11-26(30)12-10-22/h2-12,20,23H,13-19H2,1H3,(H2,31,32,35) DBMSRNNCDIZQIM-UHFFFAOYSA-N 50117430 1-(3-Acetyl-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-urea::CHEMBL339110 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117430&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10457573 104010986 CHEMBL339110 ZINC13475812 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212248 O=C(Nc1ccc2c[nH]nc2c1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C27H29N5O/c33-27(29-24-11-10-22-18-28-31-26(22)17-24)30-25-9-5-4-8-23(25)19-32-14-12-21(13-15-32)16-20-6-2-1-3-7-20/h1-11,17-18,21H,12-16,19H2,(H,28,31)(H2,29,30,33) CVKJENRAWSRXRF-UHFFFAOYSA-N 50117423 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H-indazol-6-yl)-urea::CHEMBL442210 C-C chemokine receptor type 3 Homo sapiens 450 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117423&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11091447 104010979 CHEMBL442210 ZINC13475752 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212249 CNC(=O)c1cccc(NC(=O)Nc2cccc(OC)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C29H33FN4O3/c1-31-28(35)25-7-4-8-27(33-29(36)32-23-5-3-6-24(18-23)37-2)26(25)19-34-15-13-21(14-16-34)17-20-9-11-22(30)12-10-20/h3-12,18,21H,13-17,19H2,1-2H3,(H,31,35)(H2,32,33,36) NHUABRNOAIQQFT-UHFFFAOYSA-N 50117404 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-[3-(3-methoxy-phenyl)-ureido]-N-methyl-benzamide::CHEMBL124334 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117404&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11134936 104010960 CHEMBL124334 ZINC13475867 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212250 CC(=O)c1cccc(NC(=O)Nc2ccc(cc2CN2CCC(Cc3ccc(F)cc3)CC2)C(N)=O)c1 InChI=1S/C29H31FN4O3/c1-19(35)22-3-2-4-26(17-22)32-29(37)33-27-10-7-23(28(31)36)16-24(27)18-34-13-11-21(12-14-34)15-20-5-8-25(30)9-6-20/h2-10,16-17,21H,11-15,18H2,1H3,(H2,31,36)(H2,32,33,37) WLMDJDKSCHHUMP-UHFFFAOYSA-N 50117448 4-[3-(3-Acetyl-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide::CHEMBL340853 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10255492 104011004 CHEMBL340853 ZINC13475848 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212251 Fc1ccc(CC2CCN(Cc3ccccc3NC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C27H27FN4O/c28-24-10-8-20(9-11-24)16-21-12-14-32(15-13-21)19-23-5-1-2-7-26(23)31-27(33)30-25-6-3-4-22(17-25)18-29/h1-11,17,21H,12-16,19H2,(H2,30,31,33) QYTAAHGSIMUUTK-UHFFFAOYSA-N 50117459 1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-urea::CHEMBL338389 C-C chemokine receptor type 3 Homo sapiens 310 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117459&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11059280 104011015 CHEMBL338389 ZINC13475798 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212252 COc1cccc(NC(=O)NCc2ccccc2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C28H33N3O2/c1-33-27-13-7-12-26(19-27)30-28(32)29-20-24-10-5-6-11-25(24)21-31-16-14-23(15-17-31)18-22-8-3-2-4-9-22/h2-13,19,23H,14-18,20-21H2,1H3,(H2,29,30,32) KNTROKLIKZWXEX-UHFFFAOYSA-N 50117457 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-benzyl]-3-(3-methoxy-phenyl)-urea::CHEMBL125282 C-C chemokine receptor type 3 Homo sapiens 2400 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117457&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10983106 104011013 CHEMBL125282 ZINC13475886 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212253 OC(=O)c1cccc(NC(=O)Nc2ccccc2)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C27H28FN3O3/c28-21-11-9-19(10-12-21)17-20-13-15-31(16-14-20)18-24-23(26(32)33)7-4-8-25(24)30-27(34)29-22-5-2-1-3-6-22/h1-12,20H,13-18H2,(H,32,33)(H2,29,30,34) CSDXAAUGKFBZOA-UHFFFAOYSA-N 50117458 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-3-(3-phenyl-ureido)-benzoic acid::CHEMBL339884 C-C chemokine receptor type 3 Homo sapiens 17 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117458&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10983419 104011014 CHEMBL339884 ZINC13475860 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212254 OC1(CCN(CCCCc2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H26ClNO/c22-20-11-9-19(10-12-20)21(24)13-16-23(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,24H,4-5,8,13-17H2 IYHFUJULQNQFMX-UHFFFAOYSA-N 50027201 4-(4-Chloro-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol::CHEMBL124813 C-C chemokine receptor type 3 Homo sapiens 14500 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027201&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11609863 103936718 CHEMBL124813 ZINC13475718 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212256 OC1(CCN(CCCC(CNC(=O)Nc2ccncc2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C34H37ClN4O2/c35-30-14-12-29(13-15-30)34(41)19-24-39(25-20-34)23-7-18-33(27-8-3-1-4-9-27,28-10-5-2-6-11-28)26-37-32(40)38-31-16-21-36-22-17-31/h1-6,8-17,21-22,41H,7,18-20,23-26H2,(H2,36,37,38,40) FMFBRILFYGRZPB-UHFFFAOYSA-N 50117456 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-pyridin-4-yl-urea::CHEMBL332277 C-C chemokine receptor type 3 Homo sapiens 3500 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117456&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10875472 104011012 CHEMBL332277 ZINC27212111 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212257 OCCCNC(=O)NC(Cc1ccccc1)c1ccccc1 InChI=1S/C18H22N2O2/c21-13-7-12-19-18(22)20-17(16-10-5-2-6-11-16)14-15-8-3-1-4-9-15/h1-6,8-11,17,21H,7,12-14H2,(H2,19,20,22) ZLWPRXIKLICWMA-UHFFFAOYSA-N 50117453 1-(1,2-Diphenyl-ethyl)-3-(3-hydroxy-propyl)-urea::CHEMBL126106 C-C chemokine receptor type 3 Homo sapiens 50000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10979426 104011009 CHEMBL126106 ZINC13475878 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212260 COc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H32FN3O3/c1-35-24-6-4-5-23(18-24)30-28(34)31-26-8-3-2-7-25(26)27(33)19-32-15-13-21(14-16-32)17-20-9-11-22(29)12-10-20/h2-12,18,21,27,33H,13-17,19H2,1H3,(H2,30,31,34) MTVAGODSWYYKMQ-UHFFFAOYSA-N 50117471 1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-phenyl)-3-(3-methoxy-phenyl)-urea::CHEMBL123917 C-C chemokine receptor type 3 Homo sapiens 21 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117471&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11812807 104011027 CHEMBL123917 ZINC13475804 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212261 O=C(Nc1ccccc1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C26H29N3O/c30-26(27-24-12-5-2-6-13-24)28-25-14-8-7-11-23(25)20-29-17-15-22(16-18-29)19-21-9-3-1-4-10-21/h1-14,22H,15-20H2,(H2,27,28,30) KVVQZNYWGJXWPG-UHFFFAOYSA-N 50117412 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-phenyl-urea::CHEMBL124134 C-C chemokine receptor type 3 Homo sapiens 900 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117412&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11811443 104010968 CHEMBL124134 ZINC13475740 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212262 O=C(Nc1cccc(CN2CCC(Cc3ccccc3)CC2)c1)Nc1cccc(c1)C#N InChI=1S/C27H28N4O/c28-19-23-8-4-10-25(17-23)29-27(32)30-26-11-5-9-24(18-26)20-31-14-12-22(13-15-31)16-21-6-2-1-3-7-21/h1-11,17-18,22H,12-16,20H2,(H2,29,30,32) AZDWHTAGSYJJPS-UHFFFAOYSA-N 50117465 1-[3-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(3-cyano-phenyl)-urea::CHEMBL123957 C-C chemokine receptor type 3 Homo sapiens 450 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117465&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11144348 104011021 CHEMBL123957 ZINC00588829 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212263 Fc1ccc(F)c(NC(=O)Nc2ccccc2CN2CCC(CC2)C(=O)c2ccccc2)c1 InChI=1S/C26H25F2N3O2/c27-21-10-11-22(28)24(16-21)30-26(33)29-23-9-5-4-8-20(23)17-31-14-12-19(13-15-31)25(32)18-6-2-1-3-7-18/h1-11,16,19H,12-15,17H2,(H2,29,30,33) VSABHQVLBAWRRF-UHFFFAOYSA-N 50117470 1-[2-(4-Benzoyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea::CHEMBL340656 C-C chemokine receptor type 3 Homo sapiens 4650 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11102400 104011026 CHEMBL340656 ZINC13475781 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212264 CNC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C30H36ClN3O2/c1-32-28(35)33-23-29(24-9-4-2-5-10-24,25-11-6-3-7-12-25)17-8-20-34-21-18-30(36,19-22-34)26-13-15-27(31)16-14-26/h2-7,9-16,36H,8,17-23H2,1H3,(H2,32,33,35) QBRASFHWGCVFTA-UHFFFAOYSA-N 50117445 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-methyl-urea::CHEMBL339349 C-C chemokine receptor type 3 Homo sapiens 8300.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117445&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11049424 104011001 CHEMBL339349 ZINC13475713 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212265 CC(=O)c1cccc(NC(=O)Nc2cccc(C(N)=O)c2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C29H31FN4O3/c1-19(35)22-4-2-5-24(17-22)32-29(37)33-27-7-3-6-25(28(31)36)26(27)18-34-14-12-21(13-15-34)16-20-8-10-23(30)11-9-20/h2-11,17,21H,12-16,18H2,1H3,(H2,31,36)(H2,32,33,37) LKKLZPRTDLZFAX-UHFFFAOYSA-N 50117405 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide::CHEMBL124722 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117405&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11038430 104010961 CHEMBL124722 ZINC13475864 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212266 Fc1ccc(CCCN2CCC3C(C2)c2cccc4CCN3c24)cc1 InChI=1S/C22H25FN2/c23-18-8-6-16(7-9-18)3-2-12-24-13-11-21-20(15-24)19-5-1-4-17-10-14-25(21)22(17)19/h1,4-9,20-21H,2-3,10-15H2 GCWSOKYFEWNCMI-UHFFFAOYSA-N 50117460 9-[3-(4-Fluoro-phenyl)-propyl]-4,5,6a,7,8,9,10,10a-octahydro-pyrido[4,3-b]pyrrolo[3,2,1-hi]indole::CHEMBL340770 C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117460&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44349617 104011016 CHEMBL340770 ZINC36351998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212267 Fc1ccc(CC2CCN(Cc3ccc4ccccc4c3NC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C31H29FN4O/c32-27-12-8-22(9-13-27)18-23-14-16-36(17-15-23)21-26-11-10-25-5-1-2-7-29(25)30(26)35-31(37)34-28-6-3-4-24(19-28)20-33/h1-13,19,23H,14-18,21H2,(H2,34,35,37) GWUBGAVGGMEVNX-UHFFFAOYSA-N 50117464 1-(3-Cyano-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-naphthalen-1-yl}-urea::CHEMBL127534 C-C chemokine receptor type 3 Homo sapiens 529 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117464&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11081509 104011020 CHEMBL127534 ZINC13475815 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212268 COc1cccc(NC(=O)Nc2cc(CO)ccc2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C28H33N3O3/c1-34-26-9-5-8-25(18-26)29-28(33)30-27-17-23(20-32)10-11-24(27)19-31-14-12-22(13-15-31)16-21-6-3-2-4-7-21/h2-11,17-18,22,32H,12-16,19-20H2,1H3,(H2,29,30,33) HYQURJMMWKKORU-UHFFFAOYSA-N 50117463 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-5-hydroxymethyl-phenyl]-3-(3-methoxy-phenyl)-urea::CHEMBL421273 C-C chemokine receptor type 3 Homo sapiens 360 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117463&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10874195 104011019 CHEMBL421273 ZINC13475821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212269 Fc1ccc(F)c(NC(=O)Nc2ccccc2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C26H27F2N3O/c27-22-10-11-23(28)25(17-22)30-26(32)29-24-9-5-4-8-21(24)18-31-14-12-20(13-15-31)16-19-6-2-1-3-7-19/h1-11,17,20H,12-16,18H2,(H2,29,30,32) BGGVTZNDSREPFI-UHFFFAOYSA-N 50117472 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea::CHEMBL124583 C-C chemokine receptor type 3 Homo sapiens 1750 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117472&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10928228 104011028 CHEMBL124583 ZINC13475742 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212270 OC1(CCN(CCCC(CNC(=O)Nc2cc(F)ccc2F)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C35H36ClF2N3O2/c36-29-14-12-28(13-15-29)35(43)19-22-41(23-20-35)21-7-18-34(26-8-3-1-4-9-26,27-10-5-2-6-11-27)25-39-33(42)40-32-24-30(37)16-17-31(32)38/h1-6,8-17,24,43H,7,18-23,25H2,(H2,39,40,42) ISVKGDHOGUJFME-UHFFFAOYSA-N 50117450 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2,5-difluoro-phenyl)-urea::CHEMBL340491 C-C chemokine receptor type 3 Homo sapiens 5700 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117450&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11082578 104011006 CHEMBL340491 ZINC27214561 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212271 Fc1ccc(CC2CCN(Cc3cc4OCOc4cc3NC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C28H27FN4O3/c29-23-6-4-19(5-7-23)12-20-8-10-33(11-9-20)17-22-14-26-27(36-18-35-26)15-25(22)32-28(34)31-24-3-1-2-21(13-24)16-30/h1-7,13-15,20H,8-12,17-18H2,(H2,31,32,34) UUOHPMWYPRJKIN-UHFFFAOYSA-N 50117462 1-(3-Cyano-phenyl)-3-{6-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzo[1,3]dioxol-5-yl}-urea::CHEMBL123961 C-C chemokine receptor type 3 Homo sapiens 85.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117462&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10458117 104011018 CHEMBL123961 ZINC13475833 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212272 O=C(Nc1ccc2c[nH]nc2c1)Nc1cc2OCOc2cc1CN1CCC(Cc2ccccc2)CC1 InChI=1S/C28H29N5O3/c34-28(30-23-7-6-21-16-29-32-25(21)14-23)31-24-15-27-26(35-18-36-27)13-22(24)17-33-10-8-20(9-11-33)12-19-4-2-1-3-5-19/h1-7,13-16,20H,8-12,17-18H2,(H,29,32)(H2,30,31,34) KQFGYWZUCHKHDK-UHFFFAOYSA-N 50117466 1-[6-(4-Benzyl-piperidin-1-ylmethyl)-benzo[1,3]dioxol-5-yl]-3-(1H-indazol-6-yl)-urea::CHEMBL124966 C-C chemokine receptor type 3 Homo sapiens 260 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117466&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23497297 104011022 CHEMBL124966 ZINC27211633 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212273 Oc1ccc(NC(=O)Nc2cccc(c2)C#N)c(CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C27H28N4O2/c28-18-22-7-4-8-24(16-22)29-27(33)30-26-10-9-25(32)17-23(26)19-31-13-11-21(12-14-31)15-20-5-2-1-3-6-20/h1-10,16-17,21,32H,11-15,19H2,(H2,29,30,33) AUYJORIOBVNNLQ-UHFFFAOYSA-N 50117467 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-4-hydroxy-phenyl]-3-(3-cyano-phenyl)-urea::CHEMBL341343 C-C chemokine receptor type 3 Homo sapiens 277 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117467&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11048458 104011023 CHEMBL341343 ZINC13475872 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212276 Fc1ccc(CC2CCN(CCc3ccccc3NC(=O)Cc3ccc(F)cc3)CC2)cc1 InChI=1S/C28H30F2N2O/c29-25-9-5-21(6-10-25)19-23-13-16-32(17-14-23)18-15-24-3-1-2-4-27(24)31-28(33)20-22-7-11-26(30)12-8-22/h1-12,23H,13-20H2,(H,31,33) SQRHRTSZOOXWRY-UHFFFAOYSA-N 50117473 CHEMBL409001::N-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-2-(4-fluoro-phenyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 153 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117473&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11059385 104011029 CHEMBL409001 ZINC13475882 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212278 Fc1ccc(CC2CCN(CCc3ccccc3NC(=O)Nc3ccc(F)cc3)CC2)cc1 InChI=1S/C27H29F2N3O/c28-23-7-5-20(6-8-23)19-21-13-16-32(17-14-21)18-15-22-3-1-2-4-26(22)31-27(33)30-25-11-9-24(29)10-12-25/h1-12,21H,13-19H2,(H2,30,31,33) RPTYSBINMOMNIZ-UHFFFAOYSA-N 50117478 1-(2-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-3-(4-fluoro-phenyl)-urea::CHEMBL127590 C-C chemokine receptor type 3 Homo sapiens 35 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117478&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10863284 104011034 CHEMBL127590 ZINC13475883 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212279 COc1ccc(NC(=O)Nc2ccccc2CN2CCC(Cc3ccccc3)CC2)cc1 InChI=1S/C27H31N3O2/c1-32-25-13-11-24(12-14-25)28-27(31)29-26-10-6-5-9-23(26)20-30-17-15-22(16-18-30)19-21-7-3-2-4-8-21/h2-14,22H,15-20H2,1H3,(H2,28,29,31) IWXGUKFSFRGFJT-UHFFFAOYSA-N 50117479 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(4-methoxy-phenyl)-urea::CHEMBL338543 C-C chemokine receptor type 3 Homo sapiens 750 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10993686 104011035 CHEMBL338543 ZINC13475746 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212280 CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(C)=O)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C30H33FN4O3/c1-20(36)23-5-3-6-25(18-23)33-30(38)34-28-8-4-7-26(29(37)32-2)27(28)19-35-15-13-22(14-16-35)17-21-9-11-24(31)12-10-21/h3-12,18,22H,13-17,19H2,1-2H3,(H,32,37)(H2,33,34,38) AYLIGBDQTHFVLJ-UHFFFAOYSA-N 50117461 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL123611 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117461&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9892753 104011017 CHEMBL123611 ZINC03974016 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212281 OC1(CCN(CCCC(CNC(=O)Nc2ccc(cc2)C(F)(F)F)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C36H37ClF3N3O2/c37-31-16-12-29(13-17-31)35(45)21-24-43(25-22-35)23-7-20-34(27-8-3-1-4-9-27,28-10-5-2-6-11-28)26-41-33(44)42-32-18-14-30(15-19-32)36(38,39)40/h1-6,8-19,45H,7,20-26H2,(H2,41,42,44) DVTKMMOXUSPMJV-UHFFFAOYSA-N 50117452 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL333865 C-C chemokine receptor type 3 Homo sapiens 5200 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117452&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10985078 104011008 CHEMBL333865 ZINC27211926 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212282 OC1(CCN(CCCC(CNC(=O)NC2CCN(Cc3ccccc3)CC2)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C41H49ClN4O2/c42-37-19-17-36(18-20-37)41(48)24-29-45(30-25-41)26-10-23-40(34-13-6-2-7-14-34,35-15-8-3-9-16-35)32-43-39(47)44-38-21-27-46(28-22-38)31-33-11-4-1-5-12-33/h1-9,11-20,38,48H,10,21-32H2,(H2,43,44,47) LLJUTRQUTPARKU-UHFFFAOYSA-N 50117454 1-(1-Benzyl-piperidin-4-yl)-3-{5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-urea::CHEMBL333063 C-C chemokine receptor type 3 Homo sapiens 1620 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117454&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10974378 104011010 CHEMBL333063 ZINC27214936 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212283 COc1ccc(NC(=O)NCC(CCCN2CCC(O)(CC2)c2ccc(Cl)cc2)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C36H40ClN3O3/c1-43-33-19-17-32(18-20-33)39-34(41)38-27-35(28-9-4-2-5-10-28,29-11-6-3-7-12-29)21-8-24-40-25-22-36(42,23-26-40)30-13-15-31(37)16-14-30/h2-7,9-20,42H,8,21-27H2,1H3,(H2,38,39,41) NTCHDYONCQSCJY-UHFFFAOYSA-N 50117382 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(4-methoxy-phenyl)-urea::CHEMBL124084 C-C chemokine receptor type 3 Homo sapiens 7600 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117382&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11072063 104010938 CHEMBL124084 ZINC27214332 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212284 COc1ccc(NC(=O)NCc2ccccc2CN2CCC(Cc3ccccc3)CC2)cc1 InChI=1S/C28H33N3O2/c1-33-27-13-11-26(12-14-27)30-28(32)29-20-24-9-5-6-10-25(24)21-31-17-15-23(16-18-31)19-22-7-3-2-4-8-22/h2-14,23H,15-21H2,1H3,(H2,29,30,32) ONGGWTQHNBNSPL-UHFFFAOYSA-N 50117469 CHEMBL125695::xv1-[2-(4-Benzyl-piperidin-1-ylmethyl)-benzyl]-3-(4-methoxy-phenyl)-urea C-C chemokine receptor type 3 Homo sapiens 1300 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117469&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11826382 104011025 CHEMBL125695 ZINC13475888 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212285 CN(C)CCNC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C33H43ClN4O2/c1-37(2)25-21-35-31(39)36-26-32(27-10-5-3-6-11-27,28-12-7-4-8-13-28)18-9-22-38-23-19-33(40,20-24-38)29-14-16-30(34)17-15-29/h3-8,10-17,40H,9,18-26H2,1-2H3,(H2,35,36,39) FKPAJUQFRVINHR-UHFFFAOYSA-N 50117391 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(2-dimethylamino-ethyl)-urea::CHEMBL340797 C-C chemokine receptor type 3 Homo sapiens 2230 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117391&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11813735 104010947 CHEMBL340797 ZINC27214553 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212288 C[N+]1(Cc2cc(O)ccc2NC(=O)Nc2cccc(c2)C#N)CCC(Cc2ccccc2)CC1 InChI=1S/C28H30N4O2/c1-32(14-12-22(13-15-32)16-21-6-3-2-4-7-21)20-24-18-26(33)10-11-27(24)31-28(34)30-25-9-5-8-23(17-25)19-29/h2-11,17-18,22H,12-16,20H2,1H3,(H2-,30,31,33,34)/p+1 GUTYBXUEHQNHMD-UHFFFAOYSA-O 50117480 4-Benzyl-1-{2-[3-(3-cyano-phenyl)-ureido]-5-hydroxy-benzyl}-1-methyl-piperidinium; iodide::CHEMBL332591 C-C chemokine receptor type 3 Homo sapiens 21 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117480&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11103845 104011036 CHEMBL332591 ZINC13475874 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212289 OCCCNC(=O)NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C32H40ClN3O3/c33-29-15-13-28(14-16-29)32(39)18-22-36(23-19-32)21-7-17-31(26-9-3-1-4-10-26,27-11-5-2-6-12-27)25-35-30(38)34-20-8-24-37/h1-6,9-16,37,39H,7-8,17-25H2,(H2,34,35,38) SBNGTUNIBSXQPH-UHFFFAOYSA-N 50117455 1-{5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentyl}-3-(3-hydroxy-propyl)-urea::CHEMBL124127 C-C chemokine receptor type 3 Homo sapiens 2350 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117455&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10995218 104011011 CHEMBL124127 ZINC27214667 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212290 OC(CN1CCC(Cc2ccccc2)CC1)c1ccccc1NC(=O)Nc1cc(F)ccc1F InChI=1S/C27H29F2N3O2/c28-21-10-11-23(29)25(17-21)31-27(34)30-24-9-5-4-8-22(24)26(33)18-32-14-12-20(13-15-32)16-19-6-2-1-3-7-19/h1-11,17,20,26,33H,12-16,18H2,(H2,30,31,34) XINIMAZPUMKJHH-UHFFFAOYSA-N 50117468 1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(2,5-difluoro-phenyl)-urea::CHEMBL421634 C-C chemokine receptor type 3 Homo sapiens 410 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117468&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11134412 104011024 CHEMBL421634 ZINC13475759 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212291 NCC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C28H33ClN2O/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15,32H,7,16-22,30H2 MPEGRCNLPCPVSF-UHFFFAOYSA-N 50082711 1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl)-piperidin-4-ol::CHEMBL125111 C-C chemokine receptor type 3 Homo sapiens 12000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082711&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10623381 103982480 CHEMBL125111 ZINC13475717 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212292 CC(=O)c1cccc(NC(=O)Nc2cc3OCOc3cc2C[N+]2(C)CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C30H32FN3O4/c1-20(35)23-4-3-5-26(15-23)32-30(36)33-27-17-29-28(37-19-38-29)16-24(27)18-34(2)12-10-22(11-13-34)14-21-6-8-25(31)9-7-21/h3-9,15-17,22H,10-14,18-19H2,1-2H3,(H-,32,33,36)/p+1 COROQIRLVSDSBV-UHFFFAOYSA-O 50117474 1-{6-[3-(3-Acetyl-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-4-(4-fluoro-benzyl)-1-methyl-piperidinium; iodide::CHEMBL419599 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117474&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11966688 104011030 CHEMBL419599 ZINC13475876 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212293 O=C(NCc1ccccc1CN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C28H30N4O/c29-19-24-9-6-12-27(18-24)31-28(33)30-20-25-10-4-5-11-26(25)21-32-15-13-23(14-16-32)17-22-7-2-1-3-8-22/h1-12,18,23H,13-17,20-21H2,(H2,30,31,33) RRLIYYQTIBZXCK-UHFFFAOYSA-N 50117475 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-benzyl]-3-(3-cyano-phenyl)-urea::CHEMBL339934 C-C chemokine receptor type 3 Homo sapiens 2800 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117475&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10950225 104011031 CHEMBL339934 ZINC13475885 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212294 COc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C28H33N3O3/c1-34-24-11-7-10-23(19-24)29-28(33)30-26-13-6-5-12-25(26)27(32)20-31-16-14-22(15-17-31)18-21-8-3-2-4-9-21/h2-13,19,22,27,32H,14-18,20H2,1H3,(H2,29,30,33) PXKUWXKCLMVULX-UHFFFAOYSA-N 50117388 1-{2-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-ethyl]-phenyl}-3-(3-methoxy-phenyl)-urea::CHEMBL123585 C-C chemokine receptor type 3 Homo sapiens 81.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117388&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11015975 104010944 CHEMBL123585 ZINC13475763 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212295 N#CC(CCCN1CCN(Cc2ccccc2)CC1)(c1ccccc1)c1ccccc1 InChI=1S/C28H31N3/c29-24-28(26-13-6-2-7-14-26,27-15-8-3-9-16-27)17-10-18-30-19-21-31(22-20-30)23-25-11-4-1-5-12-25/h1-9,11-16H,10,17-23H2 DIMUJAOXZJEAPD-UHFFFAOYSA-N 50117406 5-(4-Benzyl-piperazin-1-yl)-2,2-diphenyl-pentanenitrile::CHEMBL124808 C-C chemokine receptor type 3 Homo sapiens 14100 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117406&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11729258 104010962 CHEMBL124808 ZINC22925890 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212296 OCc1ccc(CN2CCC(Cc3ccccc3)CC2)c(NC(=O)Nc2cccc(c2)C#N)c1 InChI=1S/C28H30N4O2/c29-18-23-7-4-8-26(16-23)30-28(34)31-27-17-24(20-33)9-10-25(27)19-32-13-11-22(12-14-32)15-21-5-2-1-3-6-21/h1-10,16-17,22,33H,11-15,19-20H2,(H2,30,31,34) TZEFEFXQXXQTHI-UHFFFAOYSA-N 50117476 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-5-hydroxymethyl-phenyl]-3-(3-cyano-phenyl)-urea::CHEMBL126174 C-C chemokine receptor type 3 Homo sapiens 114 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117476&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10983308 104011032 CHEMBL126174 ZINC13475823 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212297 OC1(CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C18H20ClNO/c19-17-8-6-16(7-9-17)18(21)10-12-20(13-11-18)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 NGJGWNDBSJUZQU-UHFFFAOYSA-N 50117477 1-Benzyl-4-(4-chloro-phenyl)-piperidin-4-ol::CHEMBL419244 C-C chemokine receptor type 3 Homo sapiens 18700 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117477&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 15907328 104011033 CHEMBL419244 ZINC13475721 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212302 O=C(NCC(c1ccccc1)c1ccccc1)Nc1ccccc1CN1CCC(CC1)C(=O)c1ccccc1 InChI=1S/C34H35N3O2/c38-33(28-16-8-3-9-17-28)29-20-22-37(23-21-29)25-30-18-10-11-19-32(30)36-34(39)35-24-31(26-12-4-1-5-13-26)27-14-6-2-7-15-27/h1-19,29,31H,20-25H2,(H2,35,36,39) DHYQOPHLANBZCR-UHFFFAOYSA-N 50117481 1-[2-(4-Benzoyl-piperidin-1-ylmethyl)-phenyl]-3-(2,2-diphenyl-ethyl)-urea::CHEMBL421274 C-C chemokine receptor type 3 Homo sapiens 3900 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117481&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10874991 104011037 CHEMBL421274 ZINC13475794 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212303 NC(=O)c1ccc(NC(=O)Nc2cccc(c2)C#N)c(CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H28FN5O2/c29-24-7-4-19(5-8-24)14-20-10-12-34(13-11-20)18-23-16-22(27(31)35)6-9-26(23)33-28(36)32-25-3-1-2-21(15-25)17-30/h1-9,15-16,20H,10-14,18H2,(H2,31,35)(H2,32,33,36) RPPHDNOQGMTZBS-UHFFFAOYSA-N 50117484 4-[3-(3-Cyano-phenyl)-ureido]-3-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-benzamide::CHEMBL124473 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117484&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11070954 104011040 CHEMBL124473 ZINC13475846 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212304 [I-].C[N+]1(Cc2cc3OCOc3cc2NC(=O)Nc2cccc(c2)C#N)CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C29H29FN4O3.HI/c1-34(11-9-21(10-12-34)13-20-5-7-24(30)8-6-20)18-23-15-27-28(37-19-36-27)16-26(23)33-29(35)32-25-4-2-3-22(14-25)17-31;/h2-8,14-16,21H,9-13,18-19H2,1H3,(H-,32,33,35);1H QIXZSGPAZVTYHY-UHFFFAOYSA-N 50117483 1-{6-[3-(3-Cyano-phenyl)-ureido]-benzo[1,3]dioxol-5-ylmethyl}-4-(4-fluoro-benzyl)-1-methyl-piperidinium; iodide::CHEMBL124689 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117483&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11017617 104011039 CHEMBL124689 ZINC13475875 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212305 C(Cc1ccccc1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C20H25N/c1-3-7-18(8-4-1)11-14-21-15-12-20(13-16-21)17-19-9-5-2-6-10-19/h1-10,20H,11-17H2 FKVJGSPOLUAUNN-UHFFFAOYSA-N 50007676 4-Benzyl-1-phenethyl-piperidine::CHEMBL18222::CHEMBL553596 C-C chemokine receptor type 3 Homo sapiens 7100 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007676&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10591473 103920946 CHEMBL18222CHEMBL553596 ZINC13475730 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212306 Fc1ccc(CC2CCN(CCc3ccccc3NC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C28H29FN4O/c29-25-10-8-21(9-11-25)18-22-12-15-33(16-13-22)17-14-24-5-1-2-7-27(24)32-28(34)31-26-6-3-4-23(19-26)20-30/h1-11,19,22H,12-18H2,(H2,31,32,34) MRUIMWWIINYUKF-UHFFFAOYSA-N 50117482 1-(3-Cyano-phenyl)-3-(2-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethyl}-phenyl)-urea::CHEMBL125549 C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10972522 104011038 CHEMBL125549 ZINC13475809 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212309 OC1(CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C28H29ClN2O/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15,32H,7,16-21H2 MEEJEEVTIVAOJP-UHFFFAOYSA-N 50027216 5-(4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl)-2,2-diphenylpentanenitrile::5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile::CHEMBL34166::VUF-2274 C-C chemokine receptor type 3 Homo sapiens 9000 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027216&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9889700 103936733 CHEMBL34166 ZINC03991118 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50212310 C(C1CCN(Cc2ccccc2)CC1)c1ccccc1 InChI=1S/C19H23N/c1-3-7-17(8-4-1)15-18-11-13-20(14-12-18)16-19-9-5-2-6-10-19/h1-10,18H,11-16H2 USWWVZJEOYCMQL-UHFFFAOYSA-N 50117399 1,4-Dibenzyl-piperidine::CHEMBL124457 C-C chemokine receptor type 3 Homo sapiens 8300.0 ChEMBL 10.1021/jm0201767 10.7270/Q2MW2GG0 12166951 De Lucca, GV; Kim, UT; Johnson, C; Vargo, BJ; Welch, PK; Covington, M; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117399&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10934382 104010955 CHEMBL124457 ZINC13475731 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50022119 C[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O InChI=1S/C25H32ClN3O3S/c1-17(27-25(30)28-21-4-3-5-24(15-21)33(2,31)32)16-29-22-10-11-23(29)14-19(13-22)12-18-6-8-20(26)9-7-18/h3-9,15,17,19,22-23H,10-14,16H2,1-2H3,(H2,27,28,30)/t17-,19?,22?,23?/m1/s1 QDNRONLZDDMDPZ-UINAOQCUSA-N 50133789 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3-methanesulfonyl-phenyl)-urea::CHEMBL436363 C-C chemokine receptor type 3 Homo sapiens 65 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133789&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346154 104024543 CHEMBL436363 ZINC13553782 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50022122 C[C@H](O)[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O InChI=1S/C26H34ClN3O4S/c1-17(31)25(29-26(32)28-21-4-3-5-24(15-21)35(2,33)34)16-30-22-10-11-23(30)14-19(13-22)12-18-6-8-20(27)9-7-18/h3-9,15,17,19,22-23,25,31H,10-14,16H2,1-2H3,(H2,28,29,32)/t17-,19?,22?,23?,25-/m0/s1 SXSOGNHLWNMVOY-IEJFQWGMSA-N 50133792 1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-hydroxy-propyl}-3-(3-methanesulfonyl-phenyl)-urea::CHEMBL121637 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133792&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346153 104024546 CHEMBL121637 ZINC13553783 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50591574 COc1cc(NC(=O)N[C@H](C)CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)cc(OC)c1OC InChI=1S/C27H36ClN3O4/c1-17(29-27(32)30-21-14-24(33-2)26(35-4)25(15-21)34-3)16-31-22-9-10-23(31)13-19(12-22)11-18-5-7-20(28)8-6-18/h5-8,14-15,17,19,22-23H,9-13,16H2,1-4H3,(H2,29,30,32)/t17-,19?,22?,23?/m1/s1 HLDKNBAUHHXAGK-UINAOQCUSA-N 50133796 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL121905 C-C chemokine receptor type 3 Homo sapiens 4.7 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133796&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346194 104024550 CHEMBL121905 ZINC13553781 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50591575 COc1cc(NC(=O)N[C@@H](CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)[C@H](C)O)cc(OC)c1OC InChI=1S/C28H38ClN3O5/c1-17(33)24(31-28(34)30-21-14-25(35-2)27(37-4)26(15-21)36-3)16-32-22-9-10-23(32)13-19(12-22)11-18-5-7-20(29)8-6-18/h5-8,14-15,17,19,22-24,33H,9-13,16H2,1-4H3,(H2,30,31,34)/t17-,19?,22?,23?,24-/m0/s1 RQFRVKNYCADNRP-GBDXXHDTSA-N 50133793 1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-hydroxy-propyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL431670 C-C chemokine receptor type 3 Homo sapiens 2.4 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133793&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346210 104024547 CHEMBL431670 ZINC27180458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260609 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-12-15-34(16-13-20)14-3-17-38-24-8-5-22(31)6-9-24)25-10-7-23(32)18-27(25)35(26)28-11-4-21(19-33-28)30(36)37/h4-11,18-20H,2-3,12-17H2,1H3,(H,36,37) YUCBOQQXHCEAOT-UHFFFAOYSA-N 50041195 CHEMBL3355956 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041195&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024651 313067645 CHEMBL3355956 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260610 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-12-15-34(16-13-20)14-3-17-38-24-8-5-22(31)6-9-24)25-10-7-23(32)18-27(25)35(26)28-11-4-21(19-33-28)30(36)37/h4-11,18-20H,2-3,12-17H2,1H3,(H,36,37) YUCBOQQXHCEAOT-UHFFFAOYSA-N 50041195 CHEMBL3355956 C-C chemokine receptor type 3 Homo sapiens 532 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041195&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024651 313067645 CHEMBL3355956 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260611 CCc1[nH]c2cc(C)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C25H31FN2S/c1-3-23-25(22-10-5-18(2)17-24(22)27-23)19-11-14-28(15-12-19)13-4-16-29-21-8-6-20(26)7-9-21/h5-10,17,19,27H,3-4,11-16H2,1-2H3 TVSACSZJCZUBIY-UHFFFAOYSA-N 50041186 CHEMBL3355945 C-C chemokine receptor type 3 Homo sapiens 46 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041186&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721195 312697464 CHEMBL3355945 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260612 CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3 RUBACXIFRPVRKI-UHFFFAOYSA-N 50041187 CHEMBL3355946 C-C chemokine receptor type 3 Homo sapiens 86 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041187&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721196 313067637 CHEMBL3355946 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260613 CCc1[nH]c2cc(OC)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C25H31FN2OS/c1-3-23-25(22-10-7-20(29-2)17-24(22)27-23)18-11-14-28(15-12-18)13-4-16-30-21-8-5-19(26)6-9-21/h5-10,17-18,27H,3-4,11-16H2,1-2H3 LQECSCQKFZFLPJ-UHFFFAOYSA-N 50041188 CHEMBL3355947 C-C chemokine receptor type 3 Homo sapiens 190 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041188&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721197 313067638 CHEMBL3355947 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260614 CCc1[nH]c2cc(ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1)C(N)=O InChI=1S/C25H30FN3OS/c1-2-22-24(21-9-4-18(25(27)30)16-23(21)28-22)17-10-13-29(14-11-17)12-3-15-31-20-7-5-19(26)6-8-20/h4-9,16-17,28H,2-3,10-15H2,1H3,(H2,27,30) HACDQWKCIZHKJO-UHFFFAOYSA-N 50041200 CHEMBL3355948 C-C chemokine receptor type 3 Homo sapiens 310 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041200&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721198 313067650 CHEMBL3355948 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260615 CCc1[nH]c2cc(ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1)C(O)=O InChI=1S/C25H29FN2O2S/c1-2-22-24(21-9-4-18(25(29)30)16-23(21)27-22)17-10-13-28(14-11-17)12-3-15-31-20-7-5-19(26)6-8-20/h4-9,16-17,27H,2-3,10-15H2,1H3,(H,29,30) YMDBLLFLWGQRTQ-UHFFFAOYSA-N 50041189 CHEMBL3355949 C-C chemokine receptor type 3 Homo sapiens 4000 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041189&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721199 313067639 CHEMBL3355949 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260616 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1C InChI=1S/C25H30F2N2S/c1-3-23-25(22-10-7-20(27)17-24(22)28(23)2)18-11-14-29(15-12-18)13-4-16-30-21-8-5-19(26)6-9-21/h5-10,17-18H,3-4,11-16H2,1-2H3 CSRQGGQDNMNQEX-UHFFFAOYSA-N 50041201 CHEMBL3355950 C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041201&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57718829 313067651 CHEMBL3355950 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260617 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccccc1 InChI=1S/C30H32F2N2S/c1-2-28-30(27-14-11-24(32)21-29(27)34(28)25-7-4-3-5-8-25)22-15-18-33(19-16-22)17-6-20-35-26-12-9-23(31)10-13-26/h3-5,7-14,21-22H,2,6,15-20H2,1H3 YWGYONXMCGHURW-UHFFFAOYSA-N 50041190 CHEMBL3355951 C-C chemokine receptor type 3 Homo sapiens 67 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041190&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952524 313067640 CHEMBL3355951 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260618 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1CC(O)=O InChI=1S/C26H30F2N2O2S/c1-2-23-26(22-9-6-20(28)16-24(22)30(23)17-25(31)32)18-10-13-29(14-11-18)12-3-15-33-21-7-4-19(27)5-8-21/h4-9,16,18H,2-3,10-15,17H2,1H3,(H,31,32) MPXYNWUUGMMVRW-UHFFFAOYSA-N 50041191 CHEMBL3355952 C-C chemokine receptor type 3 Homo sapiens 61 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041191&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24937215 313067641 CHEMBL3355952 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260619 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cc1)C(O)=O InChI=1S/C31H32F2N2O2S/c1-2-28-30(21-14-17-34(18-15-21)16-3-19-38-26-11-6-23(32)7-12-26)27-13-8-24(33)20-29(27)35(28)25-9-4-22(5-10-25)31(36)37/h4-13,20-21H,2-3,14-19H2,1H3,(H,36,37) QXCXDQFFJYBNTP-UHFFFAOYSA-N 50041192 CHEMBL3355953 C-C chemokine receptor type 3 Homo sapiens 4.9 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041192&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952526 313067642 CHEMBL3355953 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260620 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cc1)-c1nnn[nH]1 InChI=1S/C31H32F2N6S/c1-2-28-30(21-14-17-38(18-15-21)16-3-19-40-26-11-6-23(32)7-12-26)27-13-8-24(33)20-29(27)39(28)25-9-4-22(5-10-25)31-34-36-37-35-31/h4-13,20-21H,2-3,14-19H2,1H3,(H,34,35,36,37) QTAMIHYZGWVETD-UHFFFAOYSA-N 50041193 CHEMBL3355954 C-C chemokine receptor type 3 Homo sapiens 4.7 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041193&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721200 313067643 CHEMBL3355954 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260621 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1Cc1ccc(cc1)C(O)=O InChI=1S/C32H34F2N2O2S/c1-2-29-31(23-14-17-35(18-15-23)16-3-19-39-27-11-8-25(33)9-12-27)28-13-10-26(34)20-30(28)36(29)21-22-4-6-24(7-5-22)32(37)38/h4-13,20,23H,2-3,14-19,21H2,1H3,(H,37,38) ZQJAWBVNTLAXOW-UHFFFAOYSA-N 50041194 CHEMBL3355955 C-C chemokine receptor type 3 Homo sapiens 6900 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041194&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721201 313067644 CHEMBL3355955 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260625 CCOC(=O)c1ccc(nc1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-14-17-36(18-15-22)16-5-19-40-26-10-7-24(33)8-11-26)27-12-9-25(34)20-29(27)37(28)30-13-6-23(21-35-30)32(38)39-4-2/h6-13,20-22H,3-5,14-19H2,1-2H3 WCDMZYLZUNFULY-UHFFFAOYSA-N 50041197 CHEMBL3355959 C-C chemokine receptor type 3 Homo sapiens 54 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041197&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024849 313067647 CHEMBL3355959 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260626 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1cccc(n1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-13-16-34(17-14-20)15-4-18-38-23-10-7-21(31)8-11-23)24-12-9-22(32)19-27(24)35(26)28-6-3-5-25(33-28)30(36)37/h3,5-12,19-20H,2,4,13-18H2,1H3,(H,36,37) RKONWZSIRONAFM-UHFFFAOYSA-N 50041198 CHEMBL3355960 C-C chemokine receptor type 3 Homo sapiens 5.0 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041198&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024650 313067648 CHEMBL3355960 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260627 CCOC(=O)c1cccc(n1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-15-18-36(19-16-22)17-6-20-40-25-12-9-23(33)10-13-25)26-14-11-24(34)21-29(26)37(28)30-8-5-7-27(35-30)32(38)39-4-2/h5,7-14,21-22H,3-4,6,15-20H2,1-2H3 MFNWFHKBFKEKAN-UHFFFAOYSA-N 50041199 CHEMBL3355961 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041199&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024850 313067649 CHEMBL3355961 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260628 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1cc(ccn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-11-15-34(16-12-20)14-3-17-38-24-7-4-22(31)5-8-24)25-9-6-23(32)19-27(25)35(26)28-18-21(30(36)37)10-13-33-28/h4-10,13,18-20H,2-3,11-12,14-17H2,1H3,(H,36,37) OVJKHLOCYYVIIT-UHFFFAOYSA-N 50041088 CHEMBL3355962 C-C chemokine receptor type 3 Homo sapiens 5.0 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041088&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721202 313067622 CHEMBL3355962 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260629 CCOC(=O)c1ccnc(c1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-13-17-36(18-14-22)16-5-19-40-26-9-6-24(33)7-10-26)27-11-8-25(34)21-29(27)37(28)30-20-23(12-15-35-30)32(38)39-4-2/h6-12,15,20-22H,3-5,13-14,16-19H2,1-2H3 VJUTWTGDFJIQRL-UHFFFAOYSA-N 50041089 CHEMBL3355963 C-C chemokine receptor type 3 Homo sapiens 98 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041089&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721203 313067623 CHEMBL3355963 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260630 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)[nH]c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 50041090 CHEMBL3355964 C-C chemokine receptor type 3 Homo sapiens 11 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041090&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721204 313067624 CHEMBL3355964 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260631 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)n(-c2ccc(cn2)C(O)=O)c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C34H38Cl2FN5O3/c1-3-29-32(26-8-7-24(37)19-30(26)42(29)31-10-6-23(20-39-31)33(43)44)22-11-14-41(15-12-22)16-13-25(40-34(45)38-4-2)17-21-5-9-27(35)28(36)18-21/h5-10,18-20,22,25H,3-4,11-17H2,1-2H3,(H,43,44)(H2,38,40,45)/t25-/m0/s1 CRQFSPXWIUARST-VWLOTQADSA-N 50041091 CHEMBL3355965 C-C chemokine receptor type 3 Homo sapiens 4.0 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041091&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721205 313067625 CHEMBL3355965 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260632 CCNC(=O)N[C@@H](CCN1CCC(CC1)c1c(CC)n(-c2ccc(cn2)C(=O)OC)c2cc(F)ccc12)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C35H40Cl2FN5O3/c1-4-30-33(27-9-8-25(38)20-31(27)43(30)32-11-7-24(21-40-32)34(44)46-3)23-12-15-42(16-13-23)17-14-26(41-35(45)39-5-2)18-22-6-10-28(36)29(37)19-22/h6-11,19-21,23,26H,4-5,12-18H2,1-3H3,(H2,39,41,45)/t26-/m0/s1 LGOIHCUQXWJJQO-SANMLTNESA-N 50041092 CHEMBL3355966 C-C chemokine receptor type 3 Homo sapiens 34 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041092&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721206 313067626 CHEMBL3355966 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260647 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccccc2)CC1 InChI=1S/C24H29FN2S/c1-2-22-24(21-10-9-19(25)17-23(21)26-22)18-11-14-27(15-12-18)13-6-16-28-20-7-4-3-5-8-20/h3-5,7-10,17-18,26H,2,6,11-16H2,1H3 JBXDGESFQNPBFT-UHFFFAOYSA-N 50041157 CHEMBL3355933 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041157&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721184 312697463 CHEMBL3355933 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260648 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(C)cc2)CC1 InChI=1S/C25H31FN2S/c1-3-23-25(22-10-7-20(26)17-24(22)27-23)19-11-14-28(15-12-19)13-4-16-29-21-8-5-18(2)6-9-21/h5-10,17,19,27H,3-4,11-16H2,1-2H3 PEHVIDOBHKJWSJ-UHFFFAOYSA-N 50041158 CHEMBL3355934 C-C chemokine receptor type 3 Homo sapiens 32 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041158&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721185 313067627 CHEMBL3355934 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260649 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(O)cc2)CC1 InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-4-18(25)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-5-19(28)6-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3 QULTXLKAKCQMRD-UHFFFAOYSA-N 50041163 CHEMBL3355935 C-C chemokine receptor type 3 Homo sapiens 78 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041163&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721186 313067628 CHEMBL3355935 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260650 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(OC)cc2)CC1 InChI=1S/C25H31FN2OS/c1-3-23-25(22-10-5-19(26)17-24(22)27-23)18-11-14-28(15-12-18)13-4-16-30-21-8-6-20(29-2)7-9-21/h5-10,17-18,27H,3-4,11-16H2,1-2H3 VGSYCJKOMDSIPP-UHFFFAOYSA-N 50041166 CHEMBL3355936 C-C chemokine receptor type 3 Homo sapiens 96 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041166&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721187 313067629 CHEMBL3355936 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260651 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(cc2)C(N)=O)CC1 InChI=1S/C25H30FN3OS/c1-2-22-24(21-9-6-19(26)16-23(21)28-22)17-10-13-29(14-11-17)12-3-15-31-20-7-4-18(5-8-20)25(27)30/h4-9,16-17,28H,2-3,10-15H2,1H3,(H2,27,30) CRBGNOGVLJKUSQ-UHFFFAOYSA-N 50041167 CHEMBL3355937 C-C chemokine receptor type 3 Homo sapiens 450 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041167&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721188 313067630 CHEMBL3355937 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260652 Cc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H26F2N2S/c1-16-23(21-8-5-19(25)15-22(21)26-16)17-9-12-27(13-10-17)11-2-14-28-20-6-3-18(24)4-7-20/h3-8,15,17,26H,2,9-14H2,1H3 OVVLDNUJGJJFNW-UHFFFAOYSA-N 50041174 CHEMBL3355938 C-C chemokine receptor type 3 Homo sapiens 33 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041174&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721189 313067631 CHEMBL3355938 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260653 OCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H26F2N2OS/c24-17-2-5-19(6-3-17)29-13-1-10-27-11-8-16(9-12-27)23-20-7-4-18(25)14-21(20)26-22(23)15-28/h2-7,14,16,26,28H,1,8-13,15H2 DTLONXZATYJNCF-UHFFFAOYSA-N 50041181 CHEMBL3355939 C-C chemokine receptor type 3 Homo sapiens 99 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041181&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721190 313067632 CHEMBL3355939 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260654 COC(C)c1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 50041182 CHEMBL3355940 C-C chemokine receptor type 3 Homo sapiens 4.3 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041182&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721191 313067633 CHEMBL3355940 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260655 CCOC(=O)c1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C25H28F2N2O2S/c1-2-31-25(30)24-23(21-9-6-19(27)16-22(21)28-24)17-10-13-29(14-11-17)12-3-15-32-20-7-4-18(26)5-8-20/h4-9,16-17,28H,2-3,10-15H2,1H3 ZDNRSFQTWFIIDN-UHFFFAOYSA-N 50041183 CHEMBL3355941 C-C chemokine receptor type 3 Homo sapiens 480 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041183&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721192 313067634 CHEMBL3355941 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260656 CCc1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H29FN2S/c1-2-22-24(21-6-3-4-7-23(21)26-22)18-12-15-27(16-13-18)14-5-17-28-20-10-8-19(25)9-11-20/h3-4,6-11,18,26H,2,5,12-17H2,1H3 NMYOEGLWLBKTCW-UHFFFAOYSA-N 50041203 CHEMBL3355942 C-C chemokine receptor type 3 Homo sapiens 31 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041203&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66906657 313067653 CHEMBL3355942 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260657 OCc1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C23H27FN2OS/c24-18-6-8-19(9-7-18)28-15-3-12-26-13-10-17(11-14-26)23-20-4-1-2-5-21(20)25-22(23)16-27/h1-2,4-9,17,25,27H,3,10-16H2 IVMJBDLZRRUJCW-UHFFFAOYSA-N 50041184 CHEMBL3355943 C-C chemokine receptor type 3 Homo sapiens 66 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041184&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721193 313067635 CHEMBL3355943 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260658 COC(C)c1[nH]c2ccccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 50041185 CHEMBL3355944 C-C chemokine receptor type 3 Homo sapiens 4.8 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041185&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 118721194 313067636 CHEMBL3355944 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260659 CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1 InChI=1S/C24H28F2N2S/c1-2-22-24(21-9-6-19(26)16-23(21)27-22)17-10-13-28(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,27H,2-3,10-15H2,1H3 HUEVBCXRDKKBRQ-UHFFFAOYSA-N 50041150 CHEMBL3355932 C-C chemokine receptor type 3 Homo sapiens 5.7 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041150&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57718837 103972994 CHEMBL3355932 ZINC36215428 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260622 CCc1c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc2n1-c1ccc(cn1)C(O)=O InChI=1S/C30H31F2N3O2S/c1-2-26-29(20-12-15-34(16-13-20)14-3-17-38-24-8-5-22(31)6-9-24)25-10-7-23(32)18-27(25)35(26)28-11-4-21(19-33-28)30(36)37/h4-11,18-20H,2-3,12-17H2,1H3,(H,36,37) YUCBOQQXHCEAOT-UHFFFAOYSA-N 50041195 CHEMBL3355956 C-C chemokine receptor type 3 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041195&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25024651 313067645 CHEMBL3355956 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260623 CCOC(=O)Cn1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C28H34F2N2O2S/c1-3-25-28(24-11-8-22(30)18-26(24)32(25)19-27(33)34-4-2)20-12-15-31(16-13-20)14-5-17-35-23-9-6-21(29)7-10-23/h6-11,18,20H,3-5,12-17,19H2,1-2H3 MAFSPAYMPQWVRE-UHFFFAOYSA-N 50041202 CHEMBL3355957 C-C chemokine receptor type 3 Homo sapiens 82 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041202&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24937092 313067652 CHEMBL3355957 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50260624 CCOC(=O)c1ccc(cc1)-n1c(CC)c(C2CCN(CCCSc3ccc(F)cc3)CC2)c2ccc(F)cc12 InChI=1S/C33H36F2N2O2S/c1-3-30-32(23-16-19-36(20-17-23)18-5-21-40-28-13-8-25(34)9-14-28)29-15-10-26(35)22-31(29)37(30)27-11-6-24(7-12-27)33(38)39-4-2/h6-15,22-23H,3-5,16-21H2,1-2H3 JRCSAKBNGXSAGM-UHFFFAOYSA-N 50041196 CHEMBL3355958 C-C chemokine receptor type 3 Homo sapiens 120 ChEMBL 10.1016/j.bmcl.2014.11.063 10.7270/Q2833TNQ 25497216 Kriegl, JM; Martyres, D; Grundl, MA; Anderskewitz, R; Dollinger, H; Rast, G; Schmid, B; Seither, P; Tautermann, CS Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041196&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11952525 313067646 CHEMBL3355958 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261940 CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-4-2-5-23(17-21)27-24(30)26-12-3-13-28-14-10-20(11-15-28)16-19-6-8-22(25)9-7-19/h2,4-9,17,20H,3,10-16H2,1H3,(H2,26,27,30) JSUGTZOUOKXRQN-UHFFFAOYSA-N 50115023 1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295832 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115023&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393282 104009011 CHEMBL295832 ZINC13443505 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261941 O=C(NCCCN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-18-21-8-4-9-22(17-21)26-23(28)25-12-5-13-27-14-10-20(11-15-27)16-19-6-2-1-3-7-19/h1-4,6-9,17,20H,5,10-16H2,(H2,25,26,28) DFMMVTOIQOKHSC-UHFFFAOYSA-N 50115010 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-phenyl)-urea::CHEMBL42948 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115010&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9842640 104008998 CHEMBL42948 ZINC13443458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261942 Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-4-2-5-22(17-20)27-24(33)26-12-3-13-32-14-10-19(11-15-32)16-18-6-8-21(25)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,26,27,33) NBCZORXSDNGHOO-UHFFFAOYSA-N 50115032 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43173 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115032&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393287 104009020 CHEMBL43173 ZINC13443551 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261944 CNC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H33FN8O2/c1-28-25(36)21-14-20(24-31-32-33-34(24)2)15-23(16-21)30-26(37)29-10-4-12-35-11-3-5-19(17-35)13-18-6-8-22(27)9-7-18/h6-9,14-16,19H,3-5,10-13,17H2,1-2H3,(H,28,36)(H2,29,30,37)/t19-/m0/s1 KIYZUCFVROTDCA-IBGZPJMESA-N 50142445 3-(3-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-ureido)-N-methyl-5-(1-methyl-1H-tetrazol-5-yl)-benzamide::CHEMBL295081 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142445&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289701 104031826 CHEMBL295081 ZINC29397703 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261945 Cn1nnnc1-c1cc(Br)cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H29BrFN7O/c1-32-23(29-30-31-32)19-13-20(25)15-22(14-19)28-24(34)27-9-3-11-33-10-2-4-18(16-33)12-17-5-7-21(26)8-6-17/h5-8,13-15,18H,2-4,9-12,16H2,1H3,(H2,27,28,34)/t18-/m0/s1 SIYOVEYXDHCEIT-SFHVURJKSA-N 50142447 1-[3-Bromo-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295898 C-C chemokine receptor type 3 Homo sapiens 3.1 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289910 104031828 CHEMBL295898 ZINC29392844 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261946 CC(=O)c1cccc(NC(=O)NCCCN2CC3(Cc4ccc(F)cc4)CCC2CC3)c1 InChI=1S/C26H32FN3O2/c1-19(31)21-4-2-5-23(16-21)29-25(32)28-14-3-15-30-18-26(12-10-24(30)11-13-26)17-20-6-8-22(27)9-7-20/h2,4-9,16,24H,3,10-15,17-18H2,1H3,(H2,28,29,32) BOIFMURGRAHYDS-UHFFFAOYSA-N 50142449 1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-propyl}-urea::CHEMBL290276 C-C chemokine receptor type 3 Homo sapiens 39 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142449&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289959 104031830 CHEMBL290276 ZINC29396927 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261948 CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H32FN7O2/c1-18(35)21-14-22(25-30-31-32-33(25)2)16-24(15-21)29-26(36)28-10-4-12-34-11-3-5-20(17-34)13-19-6-8-23(27)9-7-19/h6-9,14-16,20H,3-5,10-13,17H2,1-2H3,(H2,28,29,36)/t20-/m0/s1 MRXDPGHAGCROAM-FQEVSTJZSA-N 50142451 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-[3-Acetyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295415 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289919 104031832 CHEMBL295415 ZINC29396122 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261949 Fc1cccc(CC2CCCN(CCCNC(=O)Nc3cccc(c3)C#N)C2)c1 InChI=1S/C23H27FN4O/c24-21-8-1-5-18(14-21)13-20-7-3-11-28(17-20)12-4-10-26-23(29)27-22-9-2-6-19(15-22)16-25/h1-2,5-6,8-9,14-15,20H,3-4,7,10-13,17H2,(H2,26,27,29) HLHXMMQPQUWWII-UHFFFAOYSA-N 50142452 1-(3-Cyano-phenyl)-3-{3-[3-(3-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43391 C-C chemokine receptor type 3 Homo sapiens 243 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142452&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393396 104031833 CHEMBL43391 ZINC29393873 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261951 CC(=O)c1cccc(NC(=O)NCCCN2C[C@H]3Cc4ccc(F)cc4C[C@H]3C2)c1 InChI=1S/C24H28FN3O2/c1-16(29)17-4-2-5-23(13-17)27-24(30)26-8-3-9-28-14-20-10-18-6-7-22(25)12-19(18)11-21(20)15-28/h2,4-7,12-13,20-21H,3,8-11,14-15H2,1H3,(H2,26,27,30)/t20-,21+/m1/s1 UEZCEACAQLYPRG-RTWAWAEBSA-N 50142454 1-(3-Acetyl-phenyl)-3-[3-((3aR,9aS)-6-fluoro-1,3,3a,4,9,9a-hexahydro-benzo[f]isoindol-2-yl)-propyl]-urea::CHEMBL45064 C-C chemokine receptor type 3 Homo sapiens 56 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142454&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290041 104031835 CHEMBL45064 ZINC01550873 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261952 Cn1nnnc1-c1cc(CO)cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C25H32FN7O2/c1-32-24(29-30-31-32)21-13-20(17-34)14-23(15-21)28-25(35)27-9-3-11-33-10-2-4-19(16-33)12-18-5-7-22(26)8-6-18/h5-8,13-15,19,34H,2-4,9-12,16-17H2,1H3,(H2,27,28,35)/t19-/m0/s1 RPEVCYFHNSPDAL-IBGZPJMESA-N 50142456 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-hydroxymethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL46747 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142456&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290100 104031837 CHEMBL46747 ZINC29400247 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261953 Fc1ccc(CC2CCCN(CCCNC(=O)Nc3cccc(c3)C#N)C2)c(F)c1 InChI=1S/C23H26F2N4O/c24-20-8-7-19(22(25)14-20)12-18-5-2-10-29(16-18)11-3-9-27-23(30)28-21-6-1-4-17(13-21)15-26/h1,4,6-8,13-14,18H,2-3,5,9-12,16H2,(H2,27,28,30) QGAROWKDUWSNKV-UHFFFAOYSA-N 50142455 1-(3-Cyano-phenyl)-3-{3-[3-(2,4-difluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL42264 C-C chemokine receptor type 3 Homo sapiens 19 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142455&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289763 104031836 CHEMBL42264 ZINC29393757 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261954 CC(=O)c1cccc(NC(=O)NCCCN2[C@H]3CC[C@@H]2C[C@H](Cc2ccc(F)cc2)C3)c1 InChI=1S/C26H32FN3O2/c1-18(31)21-4-2-5-23(17-21)29-26(32)28-12-3-13-30-24-10-11-25(30)16-20(15-24)14-19-6-8-22(27)9-7-19/h2,4-9,17,20,24-25H,3,10-16H2,1H3,(H2,28,29,32)/t20-,24+,25- XSCFHQOTZLKNDH-BBEFWCPCSA-N 50142460 1-(3-Acetyl-phenyl)-3-{3-[3-(4-fluoro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-urea::CHEMBL3085118 C-C chemokine receptor type 3 Homo sapiens 7.40 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142460&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68826395 104031841 CHEMBL3085118 ZINC29399998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261956 Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(F)(F)F InChI=1S/C25H29F4N7O/c1-35-23(32-33-34-35)19-13-20(25(27,28)29)15-22(14-19)31-24(37)30-9-3-11-36-10-2-4-18(16-36)12-17-5-7-21(26)8-6-17/h5-8,13-15,18H,2-4,9-12,16H2,1H3,(H2,30,31,37)/t18-/m0/s1 TZPRYUQCKRSRIX-SFHVURJKSA-N 50142458 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-5-trifluoromethyl-phenyl]-urea::CHEMBL44522 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142458&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289741 104031839 CHEMBL44522 ZINC29393950 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261957 COc1cccc(NC(=O)NCCCN2CCCC(Cc3ccccc3)C2)c1 InChI=1S/C23H31N3O2/c1-28-22-12-5-11-21(17-22)25-23(27)24-13-7-15-26-14-6-10-20(18-26)16-19-8-3-2-4-9-19/h2-5,8-9,11-12,17,20H,6-7,10,13-16,18H2,1H3,(H2,24,25,27) QHRGJOOBZYAGCN-UHFFFAOYSA-N 50142459 1-[3-(3-Benzyl-piperidin-1-yl)-propyl]-3-(3-methoxy-phenyl)-urea::CHEMBL47220 C-C chemokine receptor type 3 Homo sapiens 55 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142459&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9951882 104031840 CHEMBL47220 ZINC29402571 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261959 CC(=O)c1cccc(NC(=O)NCCCN2C[C@@H]3Cc4ccc(F)cc4C[C@H]3C2)c1 InChI=1S/C24H28FN3O2/c1-16(29)17-4-2-5-23(13-17)27-24(30)26-8-3-9-28-14-20-10-18-6-7-22(25)12-19(18)11-21(20)15-28/h2,4-7,12-13,20-21H,3,8-11,14-15H2,1H3,(H2,26,27,30)/t20-,21-/m0/s1 UEZCEACAQLYPRG-SFTDATJTSA-N 50142462 1-(3-Acetyl-phenyl)-3-[3-((3aR,9aR)-6-fluoro-1,3,3a,4,9,9a-hexahydro-benzo[f]isoindol-2-yl)-propyl]-urea::CHEMBL43066 C-C chemokine receptor type 3 Homo sapiens 49 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142462&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289699 104031843 CHEMBL43066 ZINC29398051 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261960 CC(C)n1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C26H34FN7O/c1-19(2)34-25(30-31-32-34)22-7-3-8-24(17-22)29-26(35)28-13-5-15-33-14-4-6-21(18-33)16-20-9-11-23(27)12-10-20/h3,7-12,17,19,21H,4-6,13-16,18H2,1-2H3,(H2,28,29,35)/t21-/m0/s1 KARFHGPGSOIIMP-NRFANRHFSA-N 50142461 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-isopropyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL295970 C-C chemokine receptor type 3 Homo sapiens 3.1 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142461&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290019 104031842 CHEMBL295970 ZINC29399531 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261963 Fc1ccccc1CC1CCCN(CCCNC(=O)Nc2cccc(c2)C#N)C1 InChI=1S/C23H27FN4O/c24-22-10-2-1-8-20(22)14-19-7-4-12-28(17-19)13-5-11-26-23(29)27-21-9-3-6-18(15-21)16-25/h1-3,6,8-10,15,19H,4-5,7,11-14,17H2,(H2,26,27,29) FIHBKUQPDFXYIG-UHFFFAOYSA-N 50142465 1-(3-Cyano-phenyl)-3-{3-[3-(2-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43818 C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142465&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393395 104031846 CHEMBL43818 ZINC29394233 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261964 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C23H27FN4O/c24-21-7-5-18(6-8-21)15-19-9-13-28(14-10-19)12-2-11-26-23(29)27-22-4-1-3-20(16-22)17-25/h1,3-8,16,19H,2,9-15H2,(H2,26,27,29) JHJVGMKZQAABON-UHFFFAOYSA-N 50115021 1-(3-Cyano-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43677 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393430 104009009 CHEMBL43677 ZINC13443482 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261967 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)C2)cc1 InChI=1S/C22H25FN4O/c23-20-7-5-17(6-8-20)13-19-9-12-27(16-19)11-2-10-25-22(28)26-21-4-1-3-18(14-21)15-24/h1,3-8,14,19H,2,9-13,16H2,(H2,25,26,28) IJNLKIBEOFRWDP-UHFFFAOYSA-N 50142464 1-(3-Cyano-phenyl)-3-{3-[3-(4-fluoro-benzyl)-pyrrolidin-1-yl]-propyl}-urea::CHEMBL42507 C-C chemokine receptor type 3 Homo sapiens 31 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142464&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289762 104031845 CHEMBL42507 ZINC29394735 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261968 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m0/s1 FDDSQKZQCHXOJV-FQEVSTJZSA-N 50142448 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea::1-(3-Acetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46905 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290039 104031829 CHEMBL46905 ZINC13613375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261970 Fc1ccc(C[C@@H]2CCCN(CCCNC(=O)Nc3cccc(c3)-c3cnco3)C2)cc1 InChI=1S/C25H29FN4O2/c26-22-9-7-19(8-10-22)14-20-4-2-12-30(17-20)13-3-11-28-25(31)29-23-6-1-5-21(15-23)24-16-27-18-32-24/h1,5-10,15-16,18,20H,2-4,11-14,17H2,(H2,28,29,31)/t20-/m0/s1 JAMKOULMVDGACB-FQEVSTJZSA-N 50142471 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-oxazol-5-yl-phenyl)-urea::CHEMBL47211 C-C chemokine receptor type 3 Homo sapiens 7.9 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142471&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290029 104031852 CHEMBL47211 ZINC29401127 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261971 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m1/s1 FDDSQKZQCHXOJV-HXUWFJFHSA-N 50142467 1-(3-Acetyl-phenyl)-3-{3-[(R)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL44817 C-C chemokine receptor type 3 Homo sapiens 39 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142467&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290040 104031848 CHEMBL44817 ZINC29402961 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261972 Fc1ccc(CC2CCCN(CCCNC(=O)Nc3cccc(c3)C#N)C2)cc1 InChI=1S/C23H27FN4O/c24-21-9-7-18(8-10-21)14-20-5-2-12-28(17-20)13-3-11-26-23(29)27-22-6-1-4-19(15-22)16-25/h1,4,6-10,15,20H,2-3,5,11-14,17H2,(H2,26,27,29) KWLPAWJPUXLNRQ-UHFFFAOYSA-N 50142466 1-(3-Cyano-phenyl)-3-{3-[3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295229 C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142466&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393329 104031847 CHEMBL295229 ZINC29394224 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261973 CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C26H32FN3O3/c1-18(31)22-14-23(19(2)32)16-25(15-22)29-26(33)28-10-4-12-30-11-3-5-21(17-30)13-20-6-8-24(27)9-7-20/h6-9,14-16,21H,3-5,10-13,17H2,1-2H3,(H2,28,29,33)/t21-/m0/s1 PSTIGTLOMGJZKB-NRFANRHFSA-N 50142468 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3,5-diacetylphenyl)urea::1-(3,5-Diacetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46404 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142468&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289926 104031849 CHEMBL46404 ZINC29399195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261974 COc1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C23H30FN3O2/c1-29-22-5-2-4-21(17-22)26-23(28)25-12-3-13-27-14-10-19(11-15-27)16-18-6-8-20(24)9-7-18/h2,4-9,17,19H,3,10-16H2,1H3,(H2,25,26,28) JXTQWHXHDNHUMI-UHFFFAOYSA-N 50115071 1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-methoxy-phenyl)-urea::CHEMBL42388 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115071&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393419 104009059 CHEMBL42388 ZINC13443536 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261975 Fc1ccc(C[C@@H]2CCCN(CCCNC(=O)Nc3cccc(c3)-n3ccnc3)C2)cc1 InChI=1S/C25H30FN5O/c26-22-9-7-20(8-10-22)16-21-4-2-13-30(18-21)14-3-11-28-25(32)29-23-5-1-6-24(17-23)31-15-12-27-19-31/h1,5-10,12,15,17,19,21H,2-4,11,13-14,16,18H2,(H2,28,29,32)/t21-/m0/s1 OHIYEDUJYUSSGN-NRFANRHFSA-N 50142470 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-imidazol-1-yl-phenyl)-urea::CHEMBL47122 C-C chemokine receptor type 3 Homo sapiens 7.1 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290020 104031851 CHEMBL47122 ZINC29399017 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261976 COc1cccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C23H31N3O2/c1-28-22-10-5-9-21(18-22)25-23(27)24-13-6-14-26-15-11-20(12-16-26)17-19-7-3-2-4-8-19/h2-5,7-10,18,20H,6,11-17H2,1H3,(H2,24,25,27) MOEVUYXPOZLPNN-UHFFFAOYSA-N 50115090 1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-3-(3-methoxy-phenyl)-urea::CHEMBL43666 C-C chemokine receptor type 3 Homo sapiens 300 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115090&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9951883 104009078 CHEMBL43666 ZINC13443451 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261978 O=C(NCCCN1CCCC(Cc2ccccc2)C1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-17-20-9-4-11-22(16-20)26-23(28)25-12-6-14-27-13-5-10-21(18-27)15-19-7-2-1-3-8-19/h1-4,7-9,11,16,21H,5-6,10,12-15,18H2,(H2,25,26,28) NWKFPOZMFAYKOR-UHFFFAOYSA-N 50142463 1-[3-(3-Benzyl-piperidin-1-yl)-propyl]-3-(3-cyano-phenyl)-urea::CHEMBL43655 C-C chemokine receptor type 3 Homo sapiens 41 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142463&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393315 104031844 CHEMBL43655 ZINC29395617 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261979 Fc1ccc(C[C@@H]2CCCN(CCCNC(=O)Nc3cccc(c3)-c3nnco3)C2)cc1 InChI=1S/C24H28FN5O2/c25-21-9-7-18(8-10-21)14-19-4-2-12-30(16-19)13-3-11-26-24(31)28-22-6-1-5-20(15-22)23-29-27-17-32-23/h1,5-10,15,17,19H,2-4,11-14,16H2,(H2,26,28,31)/t19-/m0/s1 KFPIFLHWICOLPS-IBGZPJMESA-N 50142446 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-(3-[1,3,4]oxadiazol-2-yl-phenyl)-urea::CHEMBL42562 C-C chemokine receptor type 3 Homo sapiens 3.6 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142446&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289877 104031827 CHEMBL42562 ZINC29394661 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261980 Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1ccccc1 InChI=1S/C30H34FN7O/c1-37-29(34-35-36-37)26-18-25(24-8-3-2-4-9-24)19-28(20-26)33-30(39)32-14-6-16-38-15-5-7-23(21-38)17-22-10-12-27(31)13-11-22/h2-4,8-13,18-20,23H,5-7,14-17,21H2,1H3,(H2,32,33,39)/t23-/m0/s1 QXDGJWGKNDYCKN-QHCPKHFHSA-N 50142469 1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[5-(1-methyl-1H-tetrazol-5-yl)-biphenyl-3-yl]-urea::CHEMBL42599 C-C chemokine receptor type 3 Homo sapiens 2.4 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142469&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289713 104031850 CHEMBL42599 ZINC29395336 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261985 Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 LCJFXGJVEJVLLZ-FQEVSTJZSA-N 50142444 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-methyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-methyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL444568 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289715 104031825 CHEMBL444568 ZINC29395019 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261986 CCn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C25H32FN7O/c1-2-33-24(29-30-31-33)21-7-3-8-23(17-21)28-25(34)27-13-5-15-32-14-4-6-20(18-32)16-19-9-11-22(26)12-10-19/h3,7-12,17,20H,2,4-6,13-16,18H2,1H3,(H2,27,28,34)/t20-/m0/s1 QJKNUMHHRFDALQ-FQEVSTJZSA-N 50142472 1-[3-(1-Ethyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL42826 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142472&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290018 104031853 CHEMBL42826 ZINC29395246 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261987 Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1 DQSLLQXQXYFIRA-IBGZPJMESA-N 50142453 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43423 C-C chemokine receptor type 3 Homo sapiens 0.600000 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289927 104031834 CHEMBL43423 ZINC29396014 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50261988 Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H32FN11O/c1-36-24(30-32-34-36)20-14-21(25-31-33-35-37(25)2)16-23(15-20)29-26(39)28-10-4-12-38-11-3-5-19(17-38)13-18-6-8-22(27)9-7-18/h6-9,14-16,19H,3-5,10-13,17H2,1-2H3,(H2,28,29,39)/t19-/m0/s1 CWHSVBGJMSCSMQ-IBGZPJMESA-N 50142457 1-[3,5-Bis-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL288009 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142457&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10459751 104031838 CHEMBL288009 ZINC29397242 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294223 Clc1cccc(Cl)c1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C18H14Cl2N2/c19-15-5-3-6-16(20)14(15)10-12-8-9-22-11-13-4-1-2-7-17(13)21-18(12)22/h1-7,10H,8-9,11H2/b12-10+ VYXFRELMSOBDRS-ZRDIBKRKSA-N 50160166 3-[1-(2,6-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL360075 C-C chemokine receptor type 3 Homo sapiens 1800 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160166&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391258 104046726 CHEMBL360075 ZINC49765464 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294224 CCc1ccccc1\C=C1/CCn2c1nc1ccccc1c2=N InChI=1S/C20H19N3/c1-2-14-7-3-4-8-15(14)13-16-11-12-23-19(21)17-9-5-6-10-18(17)22-20(16)23/h3-10,13,21H,2,11-12H2,1H3/b16-13+,21-19? WQRRZRHFOZGARK-AYSAZBKXSA-N 50160168 3-[1-(2-Ethyl-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine::CHEMBL180446 C-C chemokine receptor type 3 Homo sapiens 360 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160168&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391192 104046728 CHEMBL180446 ZINC49932940 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294225 Cc1oc2nc3\C(CCn3c(=N)c2c1C)=C\c1ccccc1Br InChI=1S/C18H16BrN3O/c1-10-11(2)23-18-15(10)16(20)22-8-7-13(17(22)21-18)9-12-5-3-4-6-14(12)19/h3-6,9,20H,7-8H2,1-2H3/b13-9+,20-16? CWBKUDPULVEBPI-ILUQACKLSA-N 50160167 8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dimethyl-7,8-dihydro-6H-furo[2,3-d]pyrrolo[1,2-a]pyrimidin-(4Z)-ylideneamine::CHEMBL183478 C-C chemokine receptor type 3 Homo sapiens 270 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160167&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391277 104046727 CHEMBL183478 ZINC49933046 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294226 CCc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C20H20N2/c1-2-15-7-3-4-8-16(15)13-17-11-12-22-14-18-9-5-6-10-19(18)21-20(17)22/h3-10,13H,2,11-12,14H2,1H3/b17-13+ VTPUDRXEVWKQNO-GHRIWEEISA-N 50160169 3-[1-(2-Ethyl-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL369778 C-C chemokine receptor type 3 Homo sapiens 1400 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160169&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391297 104046729 CHEMBL369778 ZINC49772064 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294227 C\N=c1/n2CC\C(=C/c3ccccc3Br)c2nc2ccccc12 InChI=1S/C19H16BrN3/c1-21-19-15-7-3-5-9-17(15)22-18-14(10-11-23(18)19)12-13-6-2-4-8-16(13)20/h2-9,12H,10-11H2,1H3/b14-12+,21-19- YTMALFIGGAIEON-CQQATIJTSA-N 50160170 CHEMBL360560::[3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylidene]-methyl-amine C-C chemokine receptor type 3 Homo sapiens 310 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160170&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391213 104046730 CHEMBL360560 ZINC49765453 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294228 CCC1C\C(=C/c2ccccc2Cl)C2=Nc3ccccc3CN12 InChI=1S/C20H19ClN2/c1-2-17-12-16(11-14-7-3-5-9-18(14)21)20-22-19-10-6-4-8-15(19)13-23(17)20/h3-11,17H,2,12-13H2,1H3/b16-11+ NYPYCCZGGLGZDP-LFIBNONCSA-N 50160171 3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-1-ethyl-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL180721 C-C chemokine receptor type 3 Homo sapiens 140 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160171&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391330 104046731 CHEMBL180721 ZINC49932965 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294229 Clc1ccccc1\C=C1/CCn2c1nc1ccccc1c2=N InChI=1S/C18H14ClN3/c19-15-7-3-1-5-12(15)11-13-9-10-22-17(20)14-6-2-4-8-16(14)21-18(13)22/h1-8,11,20H,9-10H2/b13-11+,20-17? ATYIDQJDFITBDK-NOYHUVOJSA-N 50160172 3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine::CHEMBL361761 C-C chemokine receptor type 3 Homo sapiens 35 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160172&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391247 104046732 CHEMBL361761 ZINC03986350 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294230 Ic1ccccc1\C=C1/CCn2c1nc1ccccc1c2=N InChI=1S/C18H14IN3/c19-15-7-3-1-5-12(15)11-13-9-10-22-17(20)14-6-2-4-8-16(14)21-18(13)22/h1-8,11,20H,9-10H2/b13-11+,20-17? RFLSPNMEACALKF-NOYHUVOJSA-N 50160173 3-[1-(2-Iodo-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine::CHEMBL183461 C-C chemokine receptor type 3 Homo sapiens 76 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160173&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391170 104046733 CHEMBL183461 ZINC03986351 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294231 Fc1ccc(\C=C2/CCN3Cc4ccccc4N=C23)c(Cl)c1 InChI=1S/C18H14ClFN2/c19-16-10-15(20)6-5-12(16)9-13-7-8-22-11-14-3-1-2-4-17(14)21-18(13)22/h1-6,9-10H,7-8,11H2/b13-9+ PZHNHGUXGNDVHI-UKTHLTGXSA-N 50160174 3-[1-(2-Chloro-4-fluoro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL180493 C-C chemokine receptor type 3 Homo sapiens 930 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160174&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391268 104046734 CHEMBL180493 ZINC49932957 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294232 Brc1ccccc1\C=C1/CCn2c1nc1ccccc1\c2=N\C#N InChI=1S/C19H13BrN4/c20-16-7-3-1-5-13(16)11-14-9-10-24-18(14)23-17-8-4-2-6-15(17)19(24)22-12-21/h1-8,11H,9-10H2/b14-11+,22-19- RRAIFXCPCLLRNH-ZDFGYQKHSA-N 50160175 3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylidene-cyanamide::CHEMBL182719 C-C chemokine receptor type 3 Homo sapiens 6100 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160175&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391235 104046735 CHEMBL182719 ZINC28356158 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294233 C1C\C(=C/c2ccccc2-c2ccccc2)C2=Nc3ccccc3CN12 InChI=1S/C24H20N2/c1-2-8-18(9-3-1)22-12-6-4-10-19(22)16-20-14-15-26-17-21-11-5-7-13-23(21)25-24(20)26/h1-13,16H,14-15,17H2/b20-16+ JOADMKLFYKUSJD-CAPFRKAQSA-N 50160176 3-[1-Biphenyl-2-yl-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL183052 C-C chemokine receptor type 3 Homo sapiens 2900 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160176&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391317 104046736 CHEMBL183052 ZINC49933053 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294234 Fc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C18H15FN2/c19-16-7-3-1-5-13(16)11-14-9-10-21-12-15-6-2-4-8-17(15)20-18(14)21/h1-8,11H,9-10,12H2/b14-11+ FRYBRTQQJWCFLX-SDNWHVSQSA-N 50160177 3-[1-(2-Fluoro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL360738 C-C chemokine receptor type 3 Homo sapiens 1400 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160177&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391276 104046737 CHEMBL360738 ZINC49765582 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294235 Cc1sc2nc3\C(CCn3c(=N)c2c1C)=C\c1ccccc1Br InChI=1S/C18H16BrN3S/c1-10-11(2)23-18-15(10)16(20)22-8-7-13(17(22)21-18)9-12-5-3-4-6-14(12)19/h3-6,9,20H,7-8H2,1-2H3/b13-9+,20-16? GGFXEIVWIMGGBS-ILUQACKLSA-N 50160179 8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dimethyl-7,8-dihydro-6H-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-(4Z)-ylideneamine::CHEMBL360268 C-C chemokine receptor type 3 Homo sapiens 260 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160179&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391176 104046739 CHEMBL360268 ZINC49765513 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294236 FC(F)(F)Oc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C19H15F3N2O/c20-19(21,22)25-17-8-4-2-5-13(17)11-14-9-10-24-12-15-6-1-3-7-16(15)23-18(14)24/h1-8,11H,9-10,12H2/b14-11+ WYXZTTITULJJOY-SDNWHVSQSA-N 50160178 3-[1-(2-Trifluoromethoxy-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL359918 C-C chemokine receptor type 3 Homo sapiens 3200 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160178&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391329 104046738 CHEMBL359918 ZINC49765483 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294237 Brc1ccccc1\C=C1/CCn2c1nc1sc3CCCCc3c1c2=N InChI=1S/C20H18BrN3S/c21-15-7-3-1-5-12(15)11-13-9-10-24-18(22)17-14-6-2-4-8-16(14)25-20(17)23-19(13)24/h1,3,5,7,11,22H,2,4,6,8-10H2/b13-11+,22-18? JIUPEJGHQOHWJG-CAYKNLLPSA-N 50160180 1-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3,5,6,7,8-hexahydro-1H-9-thia-3a,10-diaza-cyclopenta[b]fluoren-(4Z)-ylideneamine::CHEMBL181367 C-C chemokine receptor type 3 Homo sapiens 350 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160180&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391177 104046740 CHEMBL181367 ZINC49933026 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294239 CCOc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C20H20N2O/c1-2-23-19-10-6-4-7-15(19)13-16-11-12-22-14-17-8-3-5-9-18(17)21-20(16)22/h3-10,13H,2,11-12,14H2,1H3/b16-13+ QOOUHVVPSUXSSM-DTQAZKPQSA-N 50160183 3-[1-(2-Ethoxy-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL183229 C-C chemokine receptor type 3 Homo sapiens 4500 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160183&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391312 104046743 CHEMBL183229 ZINC49933055 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294240 FC(F)(F)c1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C19H15F3N2/c20-19(21,22)16-7-3-1-5-13(16)11-14-9-10-24-12-15-6-2-4-8-17(15)23-18(14)24/h1-8,11H,9-10,12H2/b14-11+ PEEOTUMYIQGPKP-SDNWHVSQSA-N 50160184 3-[1-(2-Trifluoromethyl-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL182889 C-C chemokine receptor type 3 Homo sapiens 1600 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160184&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391296 104046744 CHEMBL182889 ZINC49933039 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294241 Brc1ccccc1\C=C1/CCn2c1nc1ncccc1c2=N InChI=1S/C17H13BrN4/c18-14-6-2-1-4-11(14)10-12-7-9-22-15(19)13-5-3-8-20-16(13)21-17(12)22/h1-6,8,10,19H,7,9H2/b12-10+,19-15? PCONRXCNJWHBRJ-CUGSQWQISA-N 50160182 9-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-8,9-dihydro-7H-pyrido[2,3-d]pyrrolo[1,2-a]pyrimidin-(5Z)-ylideneamine::CHEMBL360308 C-C chemokine receptor type 3 Homo sapiens 820 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160182&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391282 104046742 CHEMBL360308 ZINC49765565 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294242 COc1ccc(\C=C2/CCn3c2nc2ccccc2c3=N)cc1 InChI=1S/C19H17N3O/c1-23-15-8-6-13(7-9-15)12-14-10-11-22-18(20)16-4-2-3-5-17(16)21-19(14)22/h2-9,12,20H,10-11H2,1H3/b14-12+,20-18? PZDOLKPETURVGH-BRXGSZSSSA-N 50160185 3-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine::CHEMBL183519 C-C chemokine receptor type 3 Homo sapiens 3900 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160185&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391212 104046745 CHEMBL183519 ZINC49933047 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294243 Clc1ccc(\C=C2/CCN3Cc4ccccc4N=C23)c(Cl)c1 InChI=1S/C18H14Cl2N2/c19-15-6-5-12(16(20)10-15)9-13-7-8-22-11-14-3-1-2-4-17(14)21-18(13)22/h1-6,9-10H,7-8,11H2/b13-9+ URMKVDLYXNAKAF-UKTHLTGXSA-N 50160186 3-[1-(2,4-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL183441 C-C chemokine receptor type 3 Homo sapiens 1700 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160186&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391318 104046746 CHEMBL183441 ZINC49933056 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294244 Brc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C18H15BrN2/c19-16-7-3-1-5-13(16)11-14-9-10-21-12-15-6-2-4-8-17(15)20-18(14)21/h1-8,11H,9-10,12H2/b14-11+ MXJSPQACYMEMAT-SDNWHVSQSA-N 50160188 3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL183429 C-C chemokine receptor type 3 Homo sapiens 90 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160188&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9797962 104046748 CHEMBL183429 ZINC13977657 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294245 Brc1ccccc1\C=C1/CCn2c1nc1scc(C3CC3)c1c2=N InChI=1S/C19H16BrN3S/c20-15-4-2-1-3-12(15)9-13-7-8-23-17(21)16-14(11-5-6-11)10-24-19(16)22-18(13)23/h1-4,9-11,21H,5-8H2/b13-9+,21-17? IGINSIZRBDPENW-CHLNCNNDSA-N 50160190 8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-3-cyclopropyl-7,8-dihydro-6H-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-(4Z)-ylideneamine::CHEMBL183520 C-C chemokine receptor type 3 Homo sapiens 290 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160190&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391252 104046750 CHEMBL183520 ZINC49933050 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294246 CN(C)c1ccc(\C=C2/CCN3Cc4ccccc4N=C23)c(Cl)c1 InChI=1S/C20H20ClN3/c1-23(2)17-8-7-14(18(21)12-17)11-15-9-10-24-13-16-5-3-4-6-19(16)22-20(15)24/h3-8,11-12H,9-10,13H2,1-2H3/b15-11+ FWMALHBOBWIGQN-RVDMUPIBSA-N 50160189 CHEMBL434151::{3-Chloro-4-[1,2-dihydro-9H-pyrrolo[2,1-b]quinazolin-(3E)-ylidenemethyl]-phenyl}-dimethyl-amine C-C chemokine receptor type 3 Homo sapiens 1400 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160189&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391307 104046749 CHEMBL434151 ZINC49813864 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294247 CC(C)(C)c1csc2nc3\C(CCn3c(=N)c12)=C\c1ccccc1Br InChI=1S/C20H20BrN3S/c1-20(2,3)14-11-25-19-16(14)17(22)24-9-8-13(18(24)23-19)10-12-6-4-5-7-15(12)21/h4-7,10-11,22H,8-9H2,1-3H3/b13-10+,22-17? AUHVLVLVAOKAMR-GOPRIXMCSA-N 50160191 8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-3-tert-butyl-7,8-dihydro-6H-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-(4Z)-ylideneamine::CHEMBL361430 C-C chemokine receptor type 3 Homo sapiens 1200 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160191&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391160 104046751 CHEMBL361430 ZINC49769785 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294248 CCCCC1C\C(=C/c2ccccc2Br)C2=Nc3ccccc3CN12 InChI=1S/C22H23BrN2/c1-2-3-10-19-14-18(13-16-8-4-6-11-20(16)23)22-24-21-12-7-5-9-17(21)15-25(19)22/h4-9,11-13,19H,2-3,10,14-15H2,1H3/b18-13+ HRGAPNBATRLDQZ-QGOAFFKASA-N 50160195 3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1-butyl-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL181984 C-C chemokine receptor type 3 Homo sapiens 250 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160195&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391331 104046755 CHEMBL181984 ZINC49932973 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294249 Fc1ccc(cc1)C1C\C(=C/c2ccccc2Br)C2=Nc3ccccc3CN12 InChI=1S/C24H18BrFN2/c25-21-7-3-1-5-17(21)13-19-14-23(16-9-11-20(26)12-10-16)28-15-18-6-2-4-8-22(18)27-24(19)28/h1-13,23H,14-15H2/b19-13+ FCXBFXNYODDCAZ-CPNJWEJPSA-N 50160196 3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1-(4-fluoro-phenyl)-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL362032 C-C chemokine receptor type 3 Homo sapiens 7900 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160196&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391240 104046756 CHEMBL362032 ZINC49769792 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294250 Brc1ccccc1\C=C1/CCn2c1nc1sccc1c2=N InChI=1S/C16H12BrN3S/c17-13-4-2-1-3-10(13)9-11-5-7-20-14(18)12-6-8-21-16(12)19-15(11)20/h1-4,6,8-9,18H,5,7H2/b11-9+,18-14? FANFUDBBDAWKMK-LHWQALLBSA-N 50160192 8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-7,8-dihydro-6H-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-(4Z)-ylideneamine::CHEMBL361149 C-C chemokine receptor type 3 Homo sapiens 28 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160192&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391236 104046752 CHEMBL361149 ZINC03986352 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294251 Clc1ccc(\C=C2/CCN3Cc4ccccc4N=C23)cc1Cl InChI=1S/C18H14Cl2N2/c19-15-6-5-12(10-16(15)20)9-13-7-8-22-11-14-3-1-2-4-17(14)21-18(13)22/h1-6,9-10H,7-8,11H2/b13-9+ ULTBPYKLRDZXQT-UKTHLTGXSA-N 50160187 3-[1-(3,4-Dichloro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL181195 C-C chemokine receptor type 3 Homo sapiens 720 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160187&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391319 104046747 CHEMBL181195 ZINC49932956 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294252 Clc1ccccc1\C=C1/CCN2Cc3ccccc3N=C12 InChI=1S/C18H15ClN2/c19-16-7-3-1-5-13(16)11-14-9-10-21-12-15-6-2-4-8-17(15)20-18(14)21/h1-8,11H,9-10,12H2/b14-11+ WWRCUWKJSTWNFG-SDNWHVSQSA-N 50160193 3-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL369351 C-C chemokine receptor type 3 Homo sapiens 110 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160193&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391171 104046753 CHEMBL369351 ZINC13977658 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294253 Brc1ccccc1\C=C1/CCn2c1nc1ccccc1c2=N InChI=1S/C18H14BrN3/c19-15-7-3-1-5-12(15)11-13-9-10-22-17(20)14-6-2-4-8-16(14)21-18(13)22/h1-8,11,20H,9-10H2/b13-11+,20-17? OESFMASRZIGVME-NOYHUVOJSA-N 50160194 3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine::CHEMBL361606 C-C chemokine receptor type 3 Homo sapiens 28 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160194&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11360133 104046754 CHEMBL361606 ZINC03986349 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294505 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccccc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H33N7O/c1-3-19-14-22(24-28-29-30-31(24)2)16-23(15-19)27-25(33)26-17-21-10-7-12-32(18-21)13-11-20-8-5-4-6-9-20/h4-6,8-9,14-16,21H,3,7,10-13,17-18H2,1-2H3,(H2,26,27,33)/t21-/m0/s1 DWHXAJPDUCUCKY-NRFANRHFSA-N 50160447 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-((S)-1-phenethyl-piperidin-3-ylmethyl)-urea::CHEMBL359609 C-C chemokine receptor type 3 Homo sapiens 3.7 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390919 104046935 CHEMBL359609 ZINC28338196 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294506 CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CCC2(C)C)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-5-19-14-21(25-31-32-33-34(25)4)16-24(15-19)30-26(36)29-17-22-18-35(13-11-27(22,2)3)12-10-20-6-8-23(28)9-7-20/h6-9,14-16,22H,5,10-13,17-18H2,1-4H3,(H2,29,30,36)/t22-/m0/s1 JLDWJHQDXOHRRF-QFIPXVFZSA-N 50160449 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-fluoro-phenyl)-ethyl]-4,4-dimethyl-piperidin-3-ylmethyl}-urea::CHEMBL362179 C-C chemokine receptor type 3 Homo sapiens 0.63 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160449&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390955 104046937 CHEMBL362179 ZINC03948537 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294507 Cn1nnnc1-c1cccc(NC(=O)NCC2CCN(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C22H26FN7O/c1-29-21(26-27-28-29)18-3-2-4-20(13-18)25-22(31)24-14-16-9-11-30(12-10-16)15-17-5-7-19(23)8-6-17/h2-8,13,16H,9-12,14-15H2,1H3,(H2,24,25,31) JNXCEDLVZXRHDH-UHFFFAOYSA-N 50160448 1-[1-(4-Fluoro-benzyl)-piperidin-4-ylmethyl]-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL180534 C-C chemokine receptor type 3 Homo sapiens 54 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390858 104046936 CHEMBL180534 ZINC28337250 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294508 Cn1nnnc1-c1cccc(NC(=O)NCC2CCCN(CCCCc3ccc(F)cc3)C2)c1 InChI=1S/C25H32FN7O/c1-32-24(29-30-31-32)21-8-4-9-23(16-21)28-25(34)27-17-20-7-5-15-33(18-20)14-3-2-6-19-10-12-22(26)13-11-19/h4,8-13,16,20H,2-3,5-7,14-15,17-18H2,1H3,(H2,27,28,34) NXUCMGITWLTTNJ-UHFFFAOYSA-N 50160451 1-{(S)-1-[4-(4-Fluoro-phenyl)-butyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL426422 C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390918 104046939 CHEMBL426422 ZINC28338140 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294509 CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CC[C@@H]2C(C)C)cc(c1)-c1nnnn1C InChI=1S/C28H38FN7O/c1-5-20-14-22(27-32-33-34-35(27)4)16-25(15-20)31-28(37)30-17-23-18-36(13-11-26(23)19(2)3)12-10-21-6-8-24(29)9-7-21/h6-9,14-16,19,23,26H,5,10-13,17-18H2,1-4H3,(H2,30,31,37)/t23-,26+/m0/s1 XDVVNMPNYGTIOU-JYFHCDHNSA-N 50160453 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4R)-1-[2-(4-fluoro-phenyl)-ethyl]-4-isopropyl-piperidin-3-ylmethyl}-urea::CHEMBL178503 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390945 104046941 CHEMBL178503 ZINC28128867 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294510 Cn1nnnc1-c1cccc(NC(=O)NC[C@H]2CCCN(CCc3ccc(F)cc3)C2)c1 InChI=1S/C23H28FN7O/c1-30-22(27-28-29-30)19-5-2-6-21(14-19)26-23(32)25-15-18-4-3-12-31(16-18)13-11-17-7-9-20(24)10-8-17/h2,5-10,14,18H,3-4,11-13,15-16H2,1H3,(H2,25,26,32)/t18-/m1/s1 VJZFYTPWAOAASO-GOSISDBHSA-N 50160452 1-{(R)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL180694 C-C chemokine receptor type 3 Homo sapiens 13 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160452&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390891 104046940 CHEMBL180694 ZINC28332087 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294511 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(C)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H35N7O/c1-4-20-14-23(25-29-30-31-32(25)3)16-24(15-20)28-26(34)27-17-22-6-5-12-33(18-22)13-11-21-9-7-19(2)8-10-21/h7-10,14-16,22H,4-6,11-13,17-18H2,1-3H3,(H2,27,28,34)/t22-/m0/s1 MZMHIRSLXFMRFA-QFIPXVFZSA-N 50160454 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-[(S)-1-(2-p-tolyl-ethyl)-piperidin-3-ylmethyl]-urea::CHEMBL360529 C-C chemokine receptor type 3 Homo sapiens 9.7 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160454&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390882 104046942 CHEMBL360529 ZINC28341491 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294512 CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CC[C@@H]2c2ccccc2)cc(c1)-c1nnnn1C InChI=1S/C31H36FN7O/c1-3-22-17-25(30-35-36-37-38(30)2)19-28(18-22)34-31(40)33-20-26-21-39(15-13-23-9-11-27(32)12-10-23)16-14-29(26)24-7-5-4-6-8-24/h4-12,17-19,26,29H,3,13-16,20-21H2,1-2H3,(H2,33,34,40)/t26-,29+/m0/s1 VEPDAXLMTILHTF-LITSAYRRSA-N 50160455 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-phenyl-piperidin-3-ylmethyl}-urea::CHEMBL361130 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160455&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390971 104046943 CHEMBL361130 ZINC28331860 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294513 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(Cl)cc3Cl)C2)cc(c1)-c1nnnn1C InChI=1S/C25H31Cl2N7O/c1-3-17-11-20(24-30-31-32-33(24)2)13-22(12-17)29-25(35)28-15-18-5-4-9-34(16-18)10-8-19-6-7-21(26)14-23(19)27/h6-7,11-14,18H,3-5,8-10,15-16H2,1-2H3,(H2,28,29,35)/t18-/m0/s1 IMIYWTMFIZBJJM-SFHVURJKSA-N 50160458 1-{(S)-1-[2-(2,4-Dichloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL180229 C-C chemokine receptor type 3 Homo sapiens 5.5 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160458&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390911 104046946 CHEMBL180229 ZINC28337089 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294514 CCc1cc(NC(=O)N[C@@H]2CCCN(CCCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-14-20(24-29-30-31-32(24)2)16-23(15-18)28-25(34)27-22-7-5-13-33(17-22)12-4-6-19-8-10-21(26)11-9-19/h8-11,14-16,22H,3-7,12-13,17H2,1-2H3,(H2,27,28,34)/t22-/m1/s1 YWAOFPGSUKFCJO-JOCHJYFZSA-N 50160459 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-yl}-urea::CHEMBL180746 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160459&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390883 104046947 CHEMBL180746 ZINC28341497 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294515 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(cc3)N(C)C)C2)cc(c1)-c1nnnn1C InChI=1S/C27H38N8O/c1-5-20-15-23(26-30-31-32-34(26)4)17-24(16-20)29-27(36)28-18-22-7-6-13-35(19-22)14-12-21-8-10-25(11-9-21)33(2)3/h8-11,15-17,22H,5-7,12-14,18-19H2,1-4H3,(H2,28,29,36)/t22-/m0/s1 SCAGRDWJBYEKCY-QFIPXVFZSA-N 50160461 1-{(S)-1-[2-(4-Dimethylamino-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL180082 C-C chemokine receptor type 3 Homo sapiens 380 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160461&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390857 104046949 CHEMBL180082 ZINC28337215 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294516 Cn1nnnc1-c1cccc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3)C2)c1 InChI=1S/C23H28FN7O/c1-30-22(27-28-29-30)19-5-2-6-21(14-19)26-23(32)25-15-18-4-3-12-31(16-18)13-11-17-7-9-20(24)10-8-17/h2,5-10,14,18H,3-4,11-13,15-16H2,1H3,(H2,25,26,32)/t18-/m0/s1 VJZFYTPWAOAASO-SFHVURJKSA-N 50160463 1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL362490 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160463&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390842 104046951 CHEMBL362490 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294517 CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CC[C@@H]2C)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-4-19-13-21(25-30-31-32-33(25)3)15-24(14-19)29-26(35)28-16-22-17-34(11-9-18(22)2)12-10-20-5-7-23(27)8-6-20/h5-8,13-15,18,22H,4,9-12,16-17H2,1-3H3,(H2,28,29,35)/t18-,22-/m0/s1 WNUYDCDUHGVMLS-AVRDEDQJSA-N 50160462 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-methyl-piperidin-3-ylmethyl}-urea::CHEMBL182086 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160462&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10096657 104046950 CHEMBL182086 ZINC03948520 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294518 Cn1nnnc1-c1cccc(NC(=O)NCC2CCN(CCc3ccc(F)cc3)CC2)c1 InChI=1S/C23H28FN7O/c1-30-22(27-28-29-30)19-3-2-4-21(15-19)26-23(32)25-16-18-10-13-31(14-11-18)12-9-17-5-7-20(24)8-6-17/h2-8,15,18H,9-14,16H2,1H3,(H2,25,26,32) HGRVCOFNGKRLBI-UHFFFAOYSA-N 50160465 1-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL360653 C-C chemokine receptor type 3 Homo sapiens 350 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160465&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390931 104046953 CHEMBL360653 ZINC28339174 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294519 CCc1cc(NC(=O)N[C@@H]2CCCN(CCCCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-3-19-15-21(25-30-31-32-33(25)2)17-24(16-19)29-26(35)28-23-8-6-14-34(18-23)13-5-4-7-20-9-11-22(27)12-10-20/h9-12,15-17,23H,3-8,13-14,18H2,1-2H3,(H2,28,29,35)/t23-/m1/s1 PMCOYPWUSGAIJE-HSZRJFAPSA-N 50160466 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[4-(4-fluoro-phenyl)-butyl]-piperidin-3-yl}-urea::CHEMBL181528 C-C chemokine receptor type 3 Homo sapiens 7.9 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160466&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390898 104046954 CHEMBL181528 ZINC28331792 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294520 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccccc3F)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-13-21(24-29-30-31-32(24)2)15-22(14-18)28-25(34)27-16-19-7-6-11-33(17-19)12-10-20-8-4-5-9-23(20)26/h4-5,8-9,13-15,19H,3,6-7,10-12,16-17H2,1-2H3,(H2,27,28,34)/t19-/m0/s1 MPAIXZGUERRIQY-IBGZPJMESA-N 50160469 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(2-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL369331 C-C chemokine receptor type 3 Homo sapiens 5.5 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160469&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390859 104046957 CHEMBL369331 ZINC28337258 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294521 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(Cl)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32ClN7O/c1-3-18-13-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-5-4-11-33(17-20)12-10-19-6-8-22(26)9-7-19/h6-9,13-15,20H,3-5,10-12,16-17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 PPCVIXMOSZTHMR-FQEVSTJZSA-N 50160464 1-{(S)-1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL178287 C-C chemokine receptor type 3 Homo sapiens 3.6 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160464&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390964 104046952 CHEMBL178287 ZINC28128795 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294522 Cn1nnnc1-c1cccc(NC(=O)NCC2CCCN(CCc3ccc(F)cc3)C2)c1 InChI=1S/C23H28FN7O/c1-30-22(27-28-29-30)19-5-2-6-21(14-19)26-23(32)25-15-18-4-3-12-31(16-18)13-11-17-7-9-20(24)10-8-17/h2,5-10,14,18H,3-4,11-13,15-16H2,1H3,(H2,25,26,32) VJZFYTPWAOAASO-UHFFFAOYSA-N 50160456 1-{(S)-1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL181575 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160456&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390978 104046944 CHEMBL181575 ZINC28332080 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294523 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3F)C2)cc(c1)-c1nnnn1C InChI=1S/C25H31F2N7O/c1-3-17-11-20(24-30-31-32-33(24)2)13-22(12-17)29-25(35)28-15-18-5-4-9-34(16-18)10-8-19-6-7-21(26)14-23(19)27/h6-7,11-14,18H,3-5,8-10,15-16H2,1-2H3,(H2,28,29,35)/t18-/m0/s1 VHWZOYLPVHCRJU-SFHVURJKSA-N 50160468 1-{(S)-1-[2-(2,4-Difluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL178506 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160468&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390938 104046956 CHEMBL178506 ZINC28131688 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294524 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-3-19-14-22(25-30-31-32-33(25)2)16-24(15-19)29-26(35)28-17-21-7-5-13-34(18-21)12-4-6-20-8-10-23(27)11-9-20/h8-11,14-16,21H,3-7,12-13,17-18H2,1-2H3,(H2,28,29,35)/t21-/m0/s1 ZNHOHPSHSBMVBS-NRFANRHFSA-N 50160470 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-urea::CHEMBL180042 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390837 104046958 CHEMBL180042 ZINC28333614 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294525 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(cc3)C(F)(F)F)C2)cc(c1)-c1nnnn1C InChI=1S/C26H32F3N7O/c1-3-18-13-21(24-32-33-34-35(24)2)15-23(14-18)31-25(37)30-16-20-5-4-11-36(17-20)12-10-19-6-8-22(9-7-19)26(27,28)29/h6-9,13-15,20H,3-5,10-12,16-17H2,1-2H3,(H2,30,31,37)/t20-/m0/s1 KXERXXCRZSCSRV-FQEVSTJZSA-N 50160471 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL181302 C-C chemokine receptor type 3 Homo sapiens 82 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160471&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390893 104046959 CHEMBL181302 ZINC28342596 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294526 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-13-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-5-4-11-33(17-20)12-10-19-6-8-22(26)9-7-19/h6-9,13-15,20H,3-5,10-12,16-17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 QYWRKBXZKYKQSY-FQEVSTJZSA-N 50160457 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL366710 C-C chemokine receptor type 3 Homo sapiens 3.40 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160457&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390838 104046945 CHEMBL366710 ZINC03948532 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294527 CCc1cc(NC(=O)NC[C@H]2CN(CCc3ccc(F)cc3)CC[C@@H]2C(F)(F)F)cc(c1)-c1nnnn1C InChI=1S/C26H31F4N7O/c1-3-17-12-19(24-33-34-35-36(24)2)14-22(13-17)32-25(38)31-15-20-16-37(11-9-23(20)26(28,29)30)10-8-18-4-6-21(27)7-5-18/h4-7,12-14,20,23H,3,8-11,15-16H2,1-2H3,(H2,31,32,38)/t20-,23-/m0/s1 PIGWHTLHRNYGHV-REWPJTCUSA-N 50160473 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(3S,4S)-1-[2-(4-fluoro-phenyl)-ethyl]-4-trifluoromethyl-piperidin-3-ylmethyl}-urea::CHEMBL180728 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160473&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390970 104046961 CHEMBL180728 ZINC28332593 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294528 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)c(F)c3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H31F2N7O/c1-3-17-11-20(24-30-31-32-33(24)2)14-21(12-17)29-25(35)28-15-19-5-4-9-34(16-19)10-8-18-6-7-22(26)23(27)13-18/h6-7,11-14,19H,3-5,8-10,15-16H2,1-2H3,(H2,28,29,35)/t19-/m0/s1 WBYZXVSMVIWDHL-IBGZPJMESA-N 50160472 1-{(S)-1-[2-(3,4-Difluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL180351 C-C chemokine receptor type 3 Homo sapiens 3.2 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160472&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390954 104046960 CHEMBL180351 ZINC28341646 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294529 Cn1nnnc1-c1cccc(NC(=O)NCC2CCN(CCCc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-5-2-6-22(16-20)27-24(33)26-17-19-11-14-32(15-12-19)13-3-4-18-7-9-21(25)10-8-18/h2,5-10,16,19H,3-4,11-15,17H2,1H3,(H2,26,27,33) IYNWAYIPRKOYBN-UHFFFAOYSA-N 50160467 1-{1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-4-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL181311 C-C chemokine receptor type 3 Homo sapiens 230 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160467&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390949 104046955 CHEMBL181311 ZINC28341517 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294530 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3cccc(Cl)c3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32ClN7O/c1-3-18-12-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-7-5-10-33(17-20)11-9-19-6-4-8-22(26)13-19/h4,6,8,12-15,20H,3,5,7,9-11,16-17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 CCBLDBBIQVRKSJ-FQEVSTJZSA-N 50160450 1-{(S)-1-[2-(3-Chloro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL361369 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160450&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11698698 104046938 CHEMBL361369 ZINC28332842 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294531 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(OC)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H35N7O2/c1-4-19-14-22(25-29-30-31-32(25)2)16-23(15-19)28-26(34)27-17-21-6-5-12-33(18-21)13-11-20-7-9-24(35-3)10-8-20/h7-10,14-16,21H,4-6,11-13,17-18H2,1-3H3,(H2,27,28,34)/t21-/m0/s1 SDOBKOPYJINRGW-NRFANRHFSA-N 50160475 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL180860 C-C chemokine receptor type 3 Homo sapiens 120 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160475&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390843 104046963 CHEMBL180860 ZINC28332679 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294532 Cn1nnnc1-c1cccc(NC(=O)NCC2CCCN(CCCc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-7-2-8-22(15-20)27-24(33)26-16-19-6-4-14-32(17-19)13-3-5-18-9-11-21(25)12-10-18/h2,7-12,15,19H,3-6,13-14,16-17H2,1H3,(H2,26,27,33) QQUPACWFQWPKMM-UHFFFAOYSA-N 50160460 1-{(S)-1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL182087 C-C chemokine receptor type 3 Homo sapiens 36 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160460&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9981262 104046948 CHEMBL182087 ZINC13976028 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294533 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3cccc(F)c3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-12-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-7-5-10-33(17-20)11-9-19-6-4-8-22(26)13-19/h4,6,8,12-15,20H,3,5,7,9-11,16-17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 PTGXYVLEQVKKRQ-FQEVSTJZSA-N 50160474 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(3-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL360062 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160474&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390848 104046962 CHEMBL360062 ZINC28332793 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294534 CCc1cc(NC(=O)NC[C@@H]2CCCN(CCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-13-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-5-4-11-33(17-20)12-10-19-6-8-22(26)9-7-19/h6-9,13-15,20H,3-5,10-12,16-17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 QYWRKBXZKYKQSY-FQEVSTJZSA-N 50160457 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(S)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL366710 C-C chemokine receptor type 3 Homo sapiens 3.4 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160457&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390838 104046945 CHEMBL366710 ZINC03948532 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294535 CCc1cc(NC(=O)NC[C@H]2CCCN(CCCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-3-19-14-22(25-30-31-32-33(25)2)16-24(15-19)29-26(35)28-17-21-7-5-13-34(18-21)12-4-6-20-8-10-23(27)11-9-20/h8-11,14-16,21H,3-7,12-13,17-18H2,1-2H3,(H2,28,29,35)/t21-/m1/s1 ZNHOHPSHSBMVBS-OAQYLSRUSA-N 50160476 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[3-(4-fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-urea::CHEMBL360039 C-C chemokine receptor type 3 Homo sapiens 2.2 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160476&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390894 104046964 CHEMBL360039 ZINC28342614 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294536 CCc1cc(NC(=O)N[C@@H]2CCCN(CCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C24H30FN7O/c1-3-17-13-19(23-28-29-30-31(23)2)15-22(14-17)27-24(33)26-21-5-4-11-32(16-21)12-10-18-6-8-20(25)9-7-18/h6-9,13-15,21H,3-5,10-12,16H2,1-2H3,(H2,26,27,33)/t21-/m1/s1 MZJUTILHBTYUKN-OAQYLSRUSA-N 50160478 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-yl}-urea::CHEMBL178278 C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160478&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390867 104046966 CHEMBL178278 ZINC28128822 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294537 CCc1cc(NC(=O)NC[C@H]2CCCN(CCc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-3-18-13-21(24-29-30-31-32(24)2)15-23(14-18)28-25(34)27-16-20-5-4-11-33(17-20)12-10-19-6-8-22(26)9-7-19/h6-9,13-15,20H,3-5,10-12,16-17H2,1-2H3,(H2,27,28,34)/t20-/m1/s1 QYWRKBXZKYKQSY-HXUWFJFHSA-N 50160482 1-[3-Ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(R)-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-urea::CHEMBL178230 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10322255 104046969 CHEMBL178230 ZINC28125700 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294538 Cn1nnnc1-c1cccc(NC(=O)NC[C@H]2CCCN(CCCc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-7-2-8-22(15-20)27-24(33)26-16-19-6-4-14-32(17-19)13-3-5-18-9-11-21(25)12-10-18/h2,7-12,15,19H,3-6,13-14,16-17H2,1H3,(H2,26,27,33)/t19-/m1/s1 QQUPACWFQWPKMM-LJQANCHMSA-N 50160479 1-{(R)-1-[3-(4-Fluoro-phenyl)-propyl]-piperidin-3-ylmethyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL362613 C-C chemokine receptor type 3 Homo sapiens 15 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390851 104046967 CHEMBL362613 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294539 CC[C@H]1CCN(CCc2ccc(F)cc2)C[C@@H]1CNC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-4-19-14-22(26-31-32-33-34(26)3)16-25(15-19)30-27(36)29-17-23-18-35(13-11-21(23)5-2)12-10-20-6-8-24(28)9-7-20/h6-9,14-16,21,23H,4-5,10-13,17-18H2,1-3H3,(H2,29,30,36)/t21-,23-/m0/s1 WLGFAARWTXZRGB-GMAHTHKFSA-N 50160481 1-{(3S,4S)-4-Ethyl-1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-3-ylmethyl}-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL178671 C-C chemokine receptor type 3 Homo sapiens 2.2 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160481&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390927 104046968 CHEMBL178671 ZINC13976032 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50294540 Cn1nnnc1-c1cccc(NC(=O)NCC2CCCN(Cc3ccc(F)cc3)C2)c1 InChI=1S/C22H26FN7O/c1-29-21(26-27-28-29)18-5-2-6-20(12-18)25-22(31)24-13-17-4-3-11-30(15-17)14-16-7-9-19(23)10-8-16/h2,5-10,12,17H,3-4,11,13-15H2,1H3,(H2,24,25,31) PIGMGISORAKQDC-UHFFFAOYSA-N 50160477 1-[(S)-1-(4-Fluoro-benzyl)-piperidin-3-ylmethyl]-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL359953 C-C chemokine receptor type 3 Homo sapiens 3500 ChEMBL 10.1016/j.bmcl.2004.11.006 10.7270/Q2H41QXT 15664858 Batt, DG; Houghton, GC; Roderick, J; Santella, JB; Wacker, DA; Welch, PK; Orlovsky, YI; Wadman, EA; Trzaskos, JM; Davies, P; Decicco, CP; Carter, PH dBristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160477&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44390963 104046965 CHEMBL359953 ZINC28128790 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297202 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1nccc2ccccc12 InChI=1S/C28H31Cl2N3O2/c1-35-26-18-33(13-9-21(26)16-19-6-7-24(29)25(30)17-19)22-10-14-32(15-11-22)28(34)27-23-5-3-2-4-20(23)8-12-31-27/h2-8,12,17,21-22,26H,9-11,13-16,18H2,1H3/t21-,26-/m1/s1 NRRVTSCGKUQBLL-QFQXNSOFSA-N 50161439 CHEMBL181034::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-isoquinolin-1-yl-methanone C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161439&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11179794 104047745 CHEMBL181034 ZINC28134839 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297203 CS(=O)(=O)N[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H32Cl2N4O3S/c1-38(36,37)32-27-18-34(12-8-21(27)15-19-4-6-24(29)25(30)16-19)23-9-13-33(14-10-23)28(35)22-5-7-26-20(17-22)3-2-11-31-26/h2-7,11,16-17,21,23,27,32H,8-10,12-15,18H2,1H3/t21-,27-/m1/s1 VUAYHTLJMIUMTI-JIPXPUAJSA-N 50161441 CHEMBL361620::N-[(3S,4S)-4-(3,4-Dichloro-benzyl)-1''-(quinoline-6-carbonyl)-[1,4'']bipiperidinyl-3-yl]-methanesulfonamide C-C chemokine receptor type 3 Homo sapiens 1002 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161441&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389678 104047747 CHEMBL361620 ZINC28132137 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297204 OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1 BKSRLDUBSLBPQQ-OFNKIYASSA-N 50161407 CHEMBL178447::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-hydroxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 50.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161407&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11466397 104047713 CHEMBL178447 ZINC28130372 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297205 Cc1ccccc1NC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H31Cl2N3O/c1-18-4-2-3-5-24(18)28-25(31)30-14-10-21(11-15-30)29-12-8-19(9-13-29)16-20-6-7-22(26)23(27)17-20/h2-7,17,19,21H,8-16H2,1H3,(H,28,31) URNUCHUQGSEAQC-UHFFFAOYSA-N 50161448 4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-carboxylic acid o-tolylamide::CHEMBL181894 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389685 104047754 CHEMBL181894 ZINC28134686 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297206 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2nccc3ccccc23)cc1Cl InChI=1S/C27H29Cl2N3O/c28-24-6-5-20(18-25(24)29)17-19-8-13-31(14-9-19)22-10-15-32(16-11-22)27(33)26-23-4-2-1-3-21(23)7-12-30-26/h1-7,12,18-19,22H,8-11,13-17H2 VSBDCHHRACGZFL-UHFFFAOYSA-N 50161447 CHEMBL180988::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-isoquinolin-1-yl-methanone C-C chemokine receptor type 3 Homo sapiens 140 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389721 104047753 CHEMBL180988 ZINC28330468 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297209 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnnc2ccccc12 InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-8-19(26)14-18-6-7-23(28)24(29)15-18)20-9-12-32(13-10-20)27(34)22-16-30-31-25-5-3-2-4-21(22)25/h2-7,15-16,19-20,26H,8-14,17H2,1H3/t19-,26-/m1/s1 GQAKZLNWAKJYFP-NIYFSFCBSA-N 50161406 CHEMBL181929::Cinnolin-4-yl-[(3S,4S)-4-(3,4-dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-methanone C-C chemokine receptor type 3 Homo sapiens 86 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161406&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389790 104047712 CHEMBL181929 ZINC28330888 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297210 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(F)cc(F)c2)CC1 InChI=1S/C26H32F2N2O/c1-19-4-2-3-5-22(19)17-26(31)30-12-8-25(9-13-30)29-10-6-20(7-11-29)14-21-15-23(27)18-24(28)16-21/h2-5,15-16,18,20,25H,6-14,17H2,1H3 LQDMIPOAVWGTKP-UHFFFAOYSA-N 50161446 1-[4-(3,5-Difluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181827 C-C chemokine receptor type 3 Homo sapiens 2255 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161446&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389690 104047752 CHEMBL181827 ZINC28134947 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297211 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnc2ccccc2n1 InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-8-19(26)14-18-6-7-21(28)22(29)15-18)20-9-12-32(13-10-20)27(34)25-16-30-23-4-2-3-5-24(23)31-25/h2-7,15-16,19-20,26H,8-14,17H2,1H3/t19-,26-/m1/s1 PWPDGEOZCXYNKM-NIYFSFCBSA-N 50161424 CHEMBL181137::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinoxalin-2-yl-methanone C-C chemokine receptor type 3 Homo sapiens 34 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161424&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389784 104047730 CHEMBL181137 ZINC28135231 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297212 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-22(19)18-26(31)30-14-10-23(11-15-30)29-12-8-20(9-13-29)16-21-6-7-24(27)25(28)17-21/h2-7,17,20,23H,8-16,18H2,1H3 GDVQQVKRPIBZGQ-UHFFFAOYSA-N 50161449 1-[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL362700 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161449&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389744 104047755 CHEMBL362700 ZINC28131260 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297213 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc3[nH]ccc3c2)cc1Cl InChI=1S/C26H29Cl2N3O/c27-23-3-1-19(16-24(23)28)15-18-6-11-30(12-7-18)22-8-13-31(14-9-22)26(32)21-2-4-25-20(17-21)5-10-29-25/h1-5,10,16-18,22,29H,6-9,11-15H2 MBZCWMPLIFTLGC-UHFFFAOYSA-N 50161445 CHEMBL178367::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-(1H-indol-5-yl)-methanone C-C chemokine receptor type 3 Homo sapiens 119 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161445&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389674 104047751 CHEMBL178367 ZINC28132119 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297214 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3[nH]ccc23)cc1Cl InChI=1S/C26H29Cl2N3O/c27-23-5-4-19(17-24(23)28)16-18-7-12-30(13-8-18)20-9-14-31(15-10-20)26(32)22-2-1-3-25-21(22)6-11-29-25/h1-6,11,17-18,20,29H,7-10,12-16H2 NGGMBNXWWMYHCB-UHFFFAOYSA-N 50161450 CHEMBL425875::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-(1H-indol-4-yl)-methanone C-C chemokine receptor type 3 Homo sapiens 111 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161450&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389750 104047756 CHEMBL425875 ZINC28131373 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297215 COc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Br)cc2)CC1 InChI=1S/C26H33BrN2O2/c1-31-25-5-3-2-4-22(25)19-26(30)29-16-12-24(13-17-29)28-14-10-21(11-15-28)18-20-6-8-23(27)9-7-20/h2-9,21,24H,10-19H2,1H3 JRCIEMCHEDOLEU-UHFFFAOYSA-N 50161451 1-[4-(4-Bromo-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-(2-methoxy-phenyl)-ethanone::CHEMBL180939 C-C chemokine receptor type 3 Homo sapiens 403.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44391800 104047757 CHEMBL180939 ZINC28341223 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297217 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cccc2cccnc12 InChI=1S/C28H31Cl2N3O2/c1-35-26-18-33(13-9-21(26)16-19-7-8-24(29)25(30)17-19)22-10-14-32(15-11-22)28(34)23-6-2-4-20-5-3-12-31-27(20)23/h2-8,12,17,21-22,26H,9-11,13-16,18H2,1H3/t21-,26-/m1/s1 RDSIIPUBKKQZFV-QFQXNSOFSA-N 50161420 CHEMBL362040::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinolin-8-yl-methanone C-C chemokine receptor type 3 Homo sapiens 18 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161420&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11214422 104047726 CHEMBL362040 ZINC28131199 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297201 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)cc2)CC1 InChI=1S/C26H33ClN2O/c1-20-4-2-3-5-23(20)19-26(30)29-16-12-25(13-17-29)28-14-10-22(11-15-28)18-21-6-8-24(27)9-7-21/h2-9,22,25H,10-19H2,1H3 LSQRQZWLLFOMJN-UHFFFAOYSA-N 50161442 1-[4-(4-Chloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL180651 C-C chemokine receptor type 3 Homo sapiens 142 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161442&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389695 104047748 CHEMBL180651 ZINC28135781 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299500 CN(C)c1ccc(cc1)C(CNCCc1ccc(cc1)C(F)(F)F)N1CCN(CC1)c1ccccc1 InChI=1S/C29H35F3N4/c1-34(2)26-14-10-24(11-15-26)28(36-20-18-35(19-21-36)27-6-4-3-5-7-27)22-33-17-16-23-8-12-25(13-9-23)29(30,31)32/h3-15,28,33H,16-22H2,1-2H3 CWEGVQWABQKZJQ-UHFFFAOYSA-N 50162344 CHEMBL193991::Dimethyl-(4-{1-(4-phenyl-piperazin-1-yl)-2-[2-(4-trifluoromethyl-phenyl)-ethylamino]-ethyl}-phenyl)-amine C-C chemokine receptor type 3 Homo sapiens 1670 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162344&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401052 104048510 CHEMBL193991 ZINC28523412 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299501 Clc1cc(Cl)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)c1 InChI=1S/C26H35Cl2N3/c27-23-17-21(18-24(28)19-23)11-12-29-20-26(22-7-3-1-4-8-22)31-15-13-30(14-16-31)25-9-5-2-6-10-25/h1,3-4,7-8,17-19,25-26,29H,2,5-6,9-16,20H2 HUEWCRPAPGAMKE-UHFFFAOYSA-N 50162346 CHEMBL365551::[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-[2-(3,5-dichloro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 80.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162346&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25056324 104048512 CHEMBL365551 ZINC28522339 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299502 CN1CCN(CC1)C(CNC(=O)Nc1ccc(C)cc1)c1ccc(cc1)C(F)(F)F InChI=1S/C22H27F3N4O/c1-16-3-9-19(10-4-16)27-21(30)26-15-20(29-13-11-28(2)12-14-29)17-5-7-18(8-6-17)22(23,24)25/h3-10,20H,11-15H2,1-2H3,(H2,26,27,30) NTSMSQNSDHTAOW-UHFFFAOYSA-N 50162345 1-[2-(4-Methyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-p-tolyl-urea::CHEMBL193732 C-C chemokine receptor type 3 Homo sapiens 10700 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162345&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401108 104048511 CHEMBL193732 ZINC28523509 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299503 CN(C)c1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(C)CC1 InChI=1S/C22H29Cl2N5O/c1-27(2)20-6-4-16(5-7-20)21(29-10-8-28(3)9-11-29)15-25-22(30)26-19-13-17(23)12-18(24)14-19/h4-7,12-14,21H,8-11,15H2,1-3H3,(H2,25,26,30) XNJGILYAIUVILP-UHFFFAOYSA-N 50162350 1-(3,5-Dichloro-phenyl)-3-[2-(4-dimethylamino-phenyl)-2-(4-methyl-piperazin-1-yl)-ethyl]-urea::CHEMBL192045 C-C chemokine receptor type 3 Homo sapiens 3810.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162350&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400950 104048516 CHEMBL192045 ZINC28478129 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299504 Fc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H29F4N3/c28-24-12-6-21(7-13-24)14-15-32-20-26(22-8-10-23(11-9-22)27(29,30)31)34-18-16-33(17-19-34)25-4-2-1-3-5-25/h1-13,26,32H,14-20H2 NITHQGQKKAWDKI-UHFFFAOYSA-N 50162347 CHEMBL194885::[2-(4-Fluoro-phenyl)-ethyl]-[2-(4-phenyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 1200 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162347&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401004 104048513 CHEMBL194885 ZINC28523034 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299505 COc1ccccc1C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H34Cl2N4O2/c1-34-25-10-6-5-9-23(25)24(18-29-26(33)30-21-16-19(27)15-20(28)17-21)32-13-11-31(12-14-32)22-7-3-2-4-8-22/h5-6,9-10,15-17,22,24H,2-4,7-8,11-14,18H2,1H3,(H2,29,30,33) IWLOGSSUYJFLKZ-UHFFFAOYSA-N 50162348 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(2-methoxy-phenyl)-ethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL194044 C-C chemokine receptor type 3 Homo sapiens 897.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162348&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401155 104048514 CHEMBL194044 ZINC28523959 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299506 COc1ccccc1C(CNC(=O)Nc1ccc(C)cc1)N1CCN(CC1)c1ccccc1 InChI=1S/C27H32N4O2/c1-21-12-14-22(15-13-21)29-27(32)28-20-25(24-10-6-7-11-26(24)33-2)31-18-16-30(17-19-31)23-8-4-3-5-9-23/h3-15,25H,16-20H2,1-2H3,(H2,28,29,32) UFFBLRLCUOZSBD-UHFFFAOYSA-N 50162351 1-[2-(2-Methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-3-p-tolyl-urea::CHEMBL370244 C-C chemokine receptor type 3 Homo sapiens 3540.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162351&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401063 104048517 CHEMBL370244 ZINC28522858 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299507 CC(C)(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C34H53N3/c1-33(2,3)29-16-12-27(13-17-29)20-21-35-26-32(28-14-18-30(19-15-28)34(4,5)6)37-24-22-36(23-25-37)31-10-8-7-9-11-31/h12-19,31-32,35H,7-11,20-26H2,1-6H3 HWYVOJAPSVGJAJ-UHFFFAOYSA-N 50162349 CHEMBL193973::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(4-tert-butyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 349 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162349&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401031 104048515 CHEMBL193973 ZINC28522969 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299508 FC(F)(F)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)cc1 InChI=1S/C27H36F3N3/c28-27(29,30)24-13-11-22(12-14-24)15-16-31-21-26(23-7-3-1-4-8-23)33-19-17-32(18-20-33)25-9-5-2-6-10-25/h1,3-4,7-8,11-14,25-26,31H,2,5-6,9-10,15-21H2 FSYTXZOPGGGBCA-UHFFFAOYSA-N 50162354 CHEMBL194040::[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 1310 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162354&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401183 104048520 CHEMBL194040 ZINC28523794 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299509 CN1CCN(CC1)C(CNCCc1ccccc1)c1ccc(cc1)C(F)(F)F InChI=1S/C22H28F3N3/c1-27-13-15-28(16-14-27)21(17-26-12-11-18-5-3-2-4-6-18)19-7-9-20(10-8-19)22(23,24)25/h2-10,21,26H,11-17H2,1H3 MJZXBXDNOCWIQF-UHFFFAOYSA-N 50162352 CHEMBL365369::[2-(4-Methyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-phenethyl-amine C-C chemokine receptor type 3 Homo sapiens 4730 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162352&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401129 104048518 CHEMBL365369 ZINC28522222 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299510 Cc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)cc1 InChI=1S/C26H36N4O/c1-21-12-14-23(15-13-21)28-26(31)27-20-25(22-8-4-2-5-9-22)30-18-16-29(17-19-30)24-10-6-3-7-11-24/h2,4-5,8-9,12-15,24-25H,3,6-7,10-11,16-20H2,1H3,(H2,27,28,31) TTWYZLSGGMOKDN-UHFFFAOYSA-N 50162353 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-3-p-tolyl-urea::CHEMBL194086 C-C chemokine receptor type 3 Homo sapiens 5390.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162353&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401145 104048519 CHEMBL194086 ZINC28523048 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299511 COc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H35F3N4O2/c1-36-24-13-11-22(12-14-24)32-26(35)31-19-25(20-7-9-21(10-8-20)27(28,29)30)34-17-15-33(16-18-34)23-5-3-2-4-6-23/h7-14,23,25H,2-6,15-19H2,1H3,(H2,31,32,35) VGXGGSFQUCVCSE-UHFFFAOYSA-N 50162355 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-(4-methoxy-phenyl)-urea::CHEMBL193810 C-C chemokine receptor type 3 Homo sapiens 1710 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162355&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401235 104048521 CHEMBL193810 ZINC28523905 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299512 Cc1cc(C)cc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1 InChI=1S/C33H42N4O/c1-25-21-26(2)23-30(22-25)35-33(38)34-24-32(29-15-13-28(14-16-29)27-9-5-3-6-10-27)37-19-17-36(18-20-37)31-11-7-4-8-12-31/h3,5-6,9-10,13-16,21-23,31-32H,4,7-8,11-12,17-20,24H2,1-2H3,(H2,34,35,38) DDHJYTODSBZYIU-UHFFFAOYSA-N 50162356 1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(3,5-dimethyl-phenyl)-urea::CHEMBL195214 C-C chemokine receptor type 3 Homo sapiens 326 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162356&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400948 104048522 CHEMBL195214 ZINC28521802 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299513 FC(F)(F)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C28H35F6N3/c29-27(30,31)23-10-6-21(7-11-23)14-15-35-20-26(22-8-12-24(13-9-22)28(32,33)34)37-18-16-36(17-19-37)25-4-2-1-3-5-25/h6-13,25-26,35H,1-5,14-20H2 ISRYLULACQBAPM-UHFFFAOYSA-N 50162360 CHEMBL372858::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 782 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162360&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401085 104048526 CHEMBL372858 ZINC28523561 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299514 COc1ccc(cc1)C(CNC(=O)Nc1ccc(C)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H38N4O2/c1-21-8-12-23(13-9-21)29-27(32)28-20-26(22-10-14-25(33-2)15-11-22)31-18-16-30(17-19-31)24-6-4-3-5-7-24/h8-15,24,26H,3-7,16-20H2,1-2H3,(H2,28,29,32) LCWVUDNFAQQNKJ-UHFFFAOYSA-N 50162358 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-3-p-tolyl-urea::CHEMBL434918 C-C chemokine receptor type 3 Homo sapiens 2250 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401067 104048524 CHEMBL434918 ZINC28520677 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299515 FC(F)(F)c1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H34Cl2F3N3/c28-23-16-20(17-24(29)18-23)10-11-33-19-26(21-6-8-22(9-7-21)27(30,31)32)35-14-12-34(13-15-35)25-4-2-1-3-5-25/h6-9,16-18,25-26,33H,1-5,10-15,19H2 LBQJLYPJBGFFKQ-UHFFFAOYSA-N 50162361 CHEMBL193507::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(3,5-dichloro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 129 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162361&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401135 104048527 CHEMBL193507 ZINC28523953 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299516 CC(C)(C)c1ccc(cc1)C(CNCCc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1 InChI=1S/C31H44F3N3/c1-30(2,3)26-15-11-25(12-16-26)29(37-21-19-36(20-22-37)28-7-5-4-6-8-28)23-35-18-17-24-9-13-27(14-10-24)31(32,33)34/h9-16,28-29,35H,4-8,17-23H2,1-3H3 LNFQHRMWUHDOMK-UHFFFAOYSA-N 50162357 CHEMBL195293::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 231.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162357&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401109 104048523 CHEMBL195293 ZINC28523340 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299517 CN1CCN(CC1)C(CNCCc1ccccc1)c1ccccc1 InChI=1S/C21H29N3/c1-23-14-16-24(17-15-23)21(20-10-6-3-7-11-20)18-22-13-12-19-8-4-2-5-9-19/h2-11,21-22H,12-18H2,1H3 IHMZKWJAQFLEFM-UHFFFAOYSA-N 50162359 CHEMBL195093::[2-(4-Methyl-piperazin-1-yl)-2-phenyl-ethyl]-phenethyl-amine C-C chemokine receptor type 3 Homo sapiens 21800.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162359&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401252 104048525 CHEMBL195093 ZINC28522964 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299518 FC(F)(F)c1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H31Cl2F3N4O/c27-20-14-21(28)16-22(15-20)33-25(36)32-17-24(18-6-8-19(9-7-18)26(29,30)31)35-12-10-34(11-13-35)23-4-2-1-3-5-23/h6-9,14-16,23-24H,1-5,10-13,17H2,(H2,32,33,36) OYBDEFVUQBRAKV-UHFFFAOYSA-N 50162362 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL176281 C-C chemokine receptor type 3 Homo sapiens 932 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162362&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387857 104048528 CHEMBL176281 ZINC28115010 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299519 CN(C)c1ccc(cc1)C(CNC(=O)Cc1ccc(cc1)C(F)(F)F)N1CCN(CC1)c1ccccc1 InChI=1S/C29H33F3N4O/c1-34(2)25-14-10-23(11-15-25)27(36-18-16-35(17-19-36)26-6-4-3-5-7-26)21-33-28(37)20-22-8-12-24(13-9-22)29(30,31)32/h3-15,27H,16-21H2,1-2H3,(H,33,37) YIZWWKPQHCWRFE-UHFFFAOYSA-N 50162363 CHEMBL372493::N-[2-(4-Dimethylamino-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-2-(4-trifluoromethyl-phenyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 34900 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162363&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401011 104048529 CHEMBL372493 ZINC28520669 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299520 CC(C)(C)c1ccc(cc1)C(CNC(=O)Cc1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C30H37N3O/c1-30(2,3)26-16-14-25(15-17-26)28(23-31-29(34)22-24-10-6-4-7-11-24)33-20-18-32(19-21-33)27-12-8-5-9-13-27/h4-17,28H,18-23H2,1-3H3,(H,31,34) JGHYIGXKJCLQEC-UHFFFAOYSA-N 50162365 CHEMBL195473::N-[2-(4-tert-Butyl-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-2-phenyl-acetamide C-C chemokine receptor type 3 Homo sapiens 11200 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162365&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400945 104048531 CHEMBL195473 ZINC28521584 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299521 COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(F)(F)F InChI=1S/C28H38F3N3O/c1-35-27-10-6-5-7-23(27)15-16-32-21-26(22-11-13-24(14-12-22)28(29,30)31)34-19-17-33(18-20-34)25-8-3-2-4-9-25/h5-7,10-14,25-26,32H,2-4,8-9,15-21H2,1H3 GKLOYHIRKOCPMO-UHFFFAOYSA-N 50162366 CHEMBL193850::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(2-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 118 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162366&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401255 104048532 CHEMBL193850 ZINC28523998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299522 COc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2OC)cc1 InChI=1S/C27H38N4O3/c1-33-23-14-12-21(13-15-23)29-27(32)28-20-25(24-10-6-7-11-26(24)34-2)31-18-16-30(17-19-31)22-8-4-3-5-9-22/h6-7,10-15,22,25H,3-5,8-9,16-20H2,1-2H3,(H2,28,29,32) BHODTMHSZWBBFD-UHFFFAOYSA-N 50162364 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(2-methoxy-phenyl)-ethyl]-3-(4-methoxy-phenyl)-urea::CHEMBL193871 C-C chemokine receptor type 3 Homo sapiens 10500 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162364&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401173 104048530 CHEMBL193871 ZINC28523990 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299523 Cc1cc(C)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1 InChI=1S/C34H45N3/c1-27-23-28(2)25-29(24-27)17-18-35-26-34(32-15-13-31(14-16-32)30-9-5-3-6-10-30)37-21-19-36(20-22-37)33-11-7-4-8-12-33/h3,5-6,9-10,13-16,23-25,33-35H,4,7-8,11-12,17-22,26H2,1-2H3 JYXNBOOVPKYADN-UHFFFAOYSA-N 50162369 CHEMBL195081::[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(3,5-dimethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 517 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162369&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401136 104048535 CHEMBL195081 ZINC28522394 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299526 CN(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(F)cc1)N1CCN(C)CC1 InChI=1S/C22H30FN5O/c1-26(2)20-10-4-17(5-11-20)21(28-14-12-27(3)13-15-28)16-24-22(29)25-19-8-6-18(23)7-9-19/h4-11,21H,12-16H2,1-3H3,(H2,24,25,29) ILIHLLMHUMGBRG-UHFFFAOYSA-N 50162370 1-[2-(4-Dimethylamino-phenyl)-2-(4-methyl-piperazin-1-yl)-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL191828 C-C chemokine receptor type 3 Homo sapiens 7750.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162370&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 43957010 104048536 CHEMBL191828 ZINC22418574 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299527 CN(C)c1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)c1ccccc1 InChI=1S/C29H38N4/c1-24-9-11-25(12-10-24)17-18-30-23-29(26-13-15-27(16-14-26)31(2)3)33-21-19-32(20-22-33)28-7-5-4-6-8-28/h4-16,29-30H,17-23H2,1-3H3 AGVWRUHDPWHVJF-UHFFFAOYSA-N 50162371 CHEMBL194435::Dimethyl-{4-[1-(4-phenyl-piperazin-1-yl)-2-(2-p-tolyl-ethylamino)-ethyl]-phenyl}-amine C-C chemokine receptor type 3 Homo sapiens 435.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162371&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400944 104048537 CHEMBL194435 ZINC28521578 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299528 CC(C)(C)c1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C30H43Cl2N3/c1-30(2,3)25-11-9-24(10-12-25)29(22-33-14-13-23-19-26(31)21-27(32)20-23)35-17-15-34(16-18-35)28-7-5-4-6-8-28/h9-12,19-21,28-29,33H,4-8,13-18,22H2,1-3H3 UOJQOOAVWIGUTE-UHFFFAOYSA-N 50162373 CHEMBL193938::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(3,5-dichloro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 224 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162373&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401225 104048539 CHEMBL193938 ZINC28523547 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299529 CC(C)CC(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C23H36Cl2N4O/c1-17(2)12-22(16-26-23(30)27-20-14-18(24)13-19(25)15-20)29-10-8-28(9-11-29)21-6-4-3-5-7-21/h13-15,17,21-22H,3-12,16H2,1-2H3,(H2,26,27,30) HVOZQNDFLSATHB-UHFFFAOYSA-N 50162372 1-[2-(4-Cyclohexyl-piperazin-1-yl)-4-methyl-pentyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL426822 C-C chemokine receptor type 3 Homo sapiens 296 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162372&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400990 104048538 CHEMBL426822 ZINC28523728 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299530 COc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C30H44N4O2/c1-30(2,3)24-12-10-23(11-13-24)28(22-31-29(35)32-25-14-16-27(36-4)17-15-25)34-20-18-33(19-21-34)26-8-6-5-7-9-26/h10-17,26,28H,5-9,18-22H2,1-4H3,(H2,31,32,35) CUUICAFATAIIHS-UHFFFAOYSA-N 50162374 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(4-methoxy-phenyl)-urea::CHEMBL193827 C-C chemokine receptor type 3 Homo sapiens 1980 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162374&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401056 104048540 CHEMBL193827 ZINC28523703 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299531 COc1ccc(NC(=O)NCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H29F3N4O2/c1-36-24-13-11-22(12-14-24)32-26(35)31-19-25(20-7-9-21(10-8-20)27(28,29)30)34-17-15-33(16-18-34)23-5-3-2-4-6-23/h2-14,25H,15-19H2,1H3,(H2,31,32,35) ZRACCWSAWFMMSZ-UHFFFAOYSA-N 50162375 1-(4-Methoxy-phenyl)-3-[2-(4-phenyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-urea::CHEMBL193334 C-C chemokine receptor type 3 Homo sapiens 14800 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162375&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401251 104048541 CHEMBL193334 ZINC28522962 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299532 COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(C)(C)C InChI=1S/C31H47N3O/c1-31(2,3)27-16-14-25(15-17-27)29(24-32-19-18-26-10-8-9-13-30(26)35-4)34-22-20-33(21-23-34)28-11-6-5-7-12-28/h8-10,13-17,28-29,32H,5-7,11-12,18-24H2,1-4H3 VFCMCYWFSLNPDX-UHFFFAOYSA-N 50162376 CHEMBL195480::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(2-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 216 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162376&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400982 104048542 CHEMBL195480 ZINC28522330 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299533 COc1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)c1ccccc1 InChI=1S/C28H35N3O/c1-23-8-10-24(11-9-23)16-17-29-22-28(25-12-14-27(32-2)15-13-25)31-20-18-30(19-21-31)26-6-4-3-5-7-26/h3-15,28-29H,16-22H2,1-2H3 JAXMSMJZMJEPQW-UHFFFAOYSA-N 50162379 CHEMBL195406::[2-(4-Methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-(2-p-tolyl-ethyl)-amine C-C chemokine receptor type 3 Homo sapiens 597.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162379&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401226 104048545 CHEMBL195406 ZINC28523472 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299534 COc1ccccc1CC(=O)NCC(N1CCN(CC1)c1ccccc1)c1ccccc1OC InChI=1S/C28H33N3O3/c1-33-26-14-8-6-10-22(26)20-28(32)29-21-25(24-13-7-9-15-27(24)34-2)31-18-16-30(17-19-31)23-11-4-3-5-12-23/h3-15,25H,16-21H2,1-2H3,(H,29,32) TVFLYDDJEYBYQR-UHFFFAOYSA-N 50162378 2-(2-Methoxy-phenyl)-N-[2-(2-methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-acetamide::CHEMBL194886 C-C chemokine receptor type 3 Homo sapiens 6000.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162378&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401005 104048544 CHEMBL194886 ZINC28523036 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299535 CC(C)(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C31H44F3N3/c1-30(2,3)26-13-9-24(10-14-26)17-18-35-23-29(25-11-15-27(16-12-25)31(32,33)34)37-21-19-36(20-22-37)28-7-5-4-6-8-28/h9-16,28-29,35H,4-8,17-23H2,1-3H3 SNGIHLKZTCMMNQ-UHFFFAOYSA-N 50162380 CHEMBL179752::[2-(4-tert-Butyl-phenyl)-ethyl]-[2-(4-cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 832 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162380&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387853 104048546 CHEMBL179752 ZINC28116357 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299536 CN1CCN(CC1)C(CNCCc1ccc(cc1)C(F)(F)F)c1ccccc1 InChI=1S/C22H28F3N3/c1-27-13-15-28(16-14-27)21(19-5-3-2-4-6-19)17-26-12-11-18-7-9-20(10-8-18)22(23,24)25/h2-10,21,26H,11-17H2,1H3 NEHOBSKADCYNHP-UHFFFAOYSA-N 50162381 CHEMBL195488::[2-(4-Methyl-piperazin-1-yl)-2-phenyl-ethyl]-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 8970.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162381&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401094 104048547 CHEMBL195488 ZINC28522678 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299537 Cc1ccc(CC(=O)NCC(N2CCN(CC2)c2ccccc2)c2ccccc2)cc1 InChI=1S/C27H31N3O/c1-22-12-14-23(15-13-22)20-27(31)28-21-26(24-8-4-2-5-9-24)30-18-16-29(17-19-30)25-10-6-3-7-11-25/h2-15,26H,16-21H2,1H3,(H,28,31) GFIKVUHWODPRCS-UHFFFAOYSA-N 50162382 CHEMBL194070::N-[2-Phenyl-2-(4-phenyl-piperazin-1-yl)-ethyl]-2-p-tolyl-acetamide C-C chemokine receptor type 3 Homo sapiens 26900 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162382&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401117 104048548 CHEMBL194070 ZINC28523107 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299538 FC(F)(F)c1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)cc1 InChI=1S/C26H33F3N4O/c27-26(28,29)21-11-13-22(14-12-21)31-25(34)30-19-24(20-7-3-1-4-8-20)33-17-15-32(16-18-33)23-9-5-2-6-10-23/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15-19H2,(H2,30,31,34) BCSKODLJXCHOJX-UHFFFAOYSA-N 50162377 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL194715 C-C chemokine receptor type 3 Homo sapiens 1460 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162377&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401086 104048543 CHEMBL194715 ZINC28523046 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299539 CN1CCN(CC1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(F)(F)F InChI=1S/C21H23Cl2F3N4O/c1-29-6-8-30(9-7-29)19(14-2-4-15(5-3-14)21(24,25)26)13-27-20(31)28-18-11-16(22)10-17(23)12-18/h2-5,10-12,19H,6-9,13H2,1H3,(H2,27,28,31) XZKKETDVVOCNFX-UHFFFAOYSA-N 50162385 1-(3,5-Dichloro-phenyl)-3-[2-(4-methyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-urea::CHEMBL191824 C-C chemokine receptor type 3 Homo sapiens 5180 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162385&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401132 104048551 CHEMBL191824 ZINC28520264 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299540 Fc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)cc1 InChI=1S/C25H33FN4O/c26-21-11-13-22(14-12-21)28-25(31)27-19-24(20-7-3-1-4-8-20)30-17-15-29(16-18-30)23-9-5-2-6-10-23/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15-19H2,(H2,27,28,31) RRUKXLMFIFTNGF-UHFFFAOYSA-N 50162383 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL194026 C-C chemokine receptor type 3 Homo sapiens 6360 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162383&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401203 104048549 CHEMBL194026 ZINC28522934 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299541 COc1ccc(cc1)C(CNCCc1cc(C)cc(C)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C29H43N3O/c1-23-19-24(2)21-25(20-23)13-14-30-22-29(26-9-11-28(33-3)12-10-26)32-17-15-31(16-18-32)27-7-5-4-6-8-27/h9-12,19-21,27,29-30H,4-8,13-18,22H2,1-3H3 XAIQPFDJGIZCFB-UHFFFAOYSA-N 50162384 CHEMBL194283::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-[2-(3,5-dimethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 50.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162384&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10003872 104048550 CHEMBL194283 ZINC28521978 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299542 CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(F)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C29H41FN4O/c1-29(2,3)23-11-9-22(10-12-23)27(21-31-28(35)32-25-15-13-24(30)14-16-25)34-19-17-33(18-20-34)26-7-5-4-6-8-26/h9-16,26-27H,4-8,17-21H2,1-3H3,(H2,31,32,35) PJVDPUISQGQTMX-UHFFFAOYSA-N 50162387 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL191719 C-C chemokine receptor type 3 Homo sapiens 1120 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162387&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401111 104048553 CHEMBL191719 ZINC28520509 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299543 CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1 InChI=1S/C30H41F3N4O/c1-29(2,3)23-11-9-22(10-12-23)27(37-19-17-36(18-20-37)26-7-5-4-6-8-26)21-34-28(38)35-25-15-13-24(14-16-25)30(31,32)33/h9-16,26-27H,4-8,17-21H2,1-3H3,(H2,34,35,38) WVCVAYYNQLGCHZ-UHFFFAOYSA-N 50162388 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL373092 C-C chemokine receptor type 3 Homo sapiens 972 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162388&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400978 104048554 CHEMBL373092 ZINC28522889 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299544 CN(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C32H50N4/c1-32(2,3)28-15-13-27(14-16-28)31(25-33-20-19-26-11-17-29(18-12-26)34(4)5)36-23-21-35(22-24-36)30-9-7-6-8-10-30/h11-18,30-31,33H,6-10,19-25H2,1-5H3 VKFKASXHWNMPCH-UHFFFAOYSA-N 50162386 (4-{2-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethylamino]-ethyl}-phenyl)-dimethyl-amine::CHEMBL191693 C-C chemokine receptor type 3 Homo sapiens 312 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162386&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401177 104048552 CHEMBL191693 ZINC28477918 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299545 Fc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H35F4N3/c28-24-12-6-21(7-13-24)14-15-32-20-26(22-8-10-23(11-9-22)27(29,30)31)34-18-16-33(17-19-34)25-4-2-1-3-5-25/h6-13,25-26,32H,1-5,14-20H2 OAXHARGKPSNZFZ-UHFFFAOYSA-N 50162391 CHEMBL192412::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(4-fluoro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 895.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162391&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400949 104048557 CHEMBL192412 ZINC28478123 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299546 COc1ccccc1C(CNC(=O)Nc1ccc(F)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H35FN4O2/c1-33-25-10-6-5-9-23(25)24(19-28-26(32)29-21-13-11-20(27)12-14-21)31-17-15-30(16-18-31)22-7-3-2-4-8-22/h5-6,9-14,22,24H,2-4,7-8,15-19H2,1H3,(H2,28,29,32) VOASLAVXWXEXCG-UHFFFAOYSA-N 50162390 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(2-methoxy-phenyl)-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL192066 C-C chemokine receptor type 3 Homo sapiens 5380.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162390&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401012 104048556 CHEMBL192066 ZINC28520673 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299547 COc1ccc(cc1)C(CNCCc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1 InChI=1S/C28H38F3N3O/c1-35-26-13-9-23(10-14-26)27(34-19-17-33(18-20-34)25-5-3-2-4-6-25)21-32-16-15-22-7-11-24(12-8-22)28(29,30)31/h7-14,25,27,32H,2-6,15-21H2,1H3 NRNLTIJPSVVKQO-UHFFFAOYSA-N 50162389 CHEMBL363181::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 929.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162389&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401089 104048555 CHEMBL363181 ZINC28523127 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299548 Fc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C26H32F4N4O/c27-21-10-12-22(13-11-21)32-25(35)31-18-24(19-6-8-20(9-7-19)26(28,29)30)34-16-14-33(15-17-34)23-4-2-1-3-5-23/h6-13,23-24H,1-5,14-18H2,(H2,31,32,35) KUHRWURAPYZJGN-UHFFFAOYSA-N 50162392 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL193332 C-C chemokine receptor type 3 Homo sapiens 1110 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162392&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401247 104048558 CHEMBL193332 ZINC28523628 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299549 CN(C)c1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C29H35F3N4/c1-34(2)26-14-8-23(9-15-26)16-17-33-22-28(24-10-12-25(13-11-24)29(30,31)32)36-20-18-35(19-21-36)27-6-4-3-5-7-27/h3-15,28,33H,16-22H2,1-2H3 IIFVPKZATLNHGU-UHFFFAOYSA-N 50162393 CHEMBL193535::Dimethyl-(4-{2-[2-(4-phenyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethylamino]-ethyl}-phenyl)-amine C-C chemokine receptor type 3 Homo sapiens 605.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162393&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401025 104048559 CHEMBL193535 ZINC28523636 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299550 CN(C)c1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccccc2)cc1 InChI=1S/C28H36N4/c1-30(2)26-15-13-24(14-16-26)17-18-29-23-28(25-9-5-3-6-10-25)32-21-19-31(20-22-32)27-11-7-4-8-12-27/h3-16,28-29H,17-23H2,1-2H3 BAQQNRHJCRAASN-UHFFFAOYSA-N 50162396 CHEMBL193656::Dimethyl-(4-{2-[2-phenyl-2-(4-phenyl-piperazin-1-yl)-ethylamino]-ethyl}-phenyl)-amine C-C chemokine receptor type 3 Homo sapiens 1770 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162396&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401188 104048562 CHEMBL193656 ZINC28523716 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299524 Fc1ccc(NC(=O)NCC(N2CCN(CC2)c2ccccc2)c2ccccc2)cc1 InChI=1S/C25H27FN4O/c26-21-11-13-22(14-12-21)28-25(31)27-19-24(20-7-3-1-4-8-20)30-17-15-29(16-18-30)23-9-5-2-6-10-23/h1-14,24H,15-19H2,(H2,27,28,31) AYHZXPXNRGUEPG-UHFFFAOYSA-N 50162368 1-(4-Fluoro-phenyl)-3-[2-phenyl-2-(4-phenyl-piperazin-1-yl)-ethyl]-urea::CHEMBL193592 C-C chemokine receptor type 3 Homo sapiens 5550.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162368&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401209 104048534 CHEMBL193592 ZINC28523881 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299551 CC(C)CC(CNC(=O)Nc1ccc(Cl)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C23H37ClN4O/c1-18(2)16-22(17-25-23(29)26-20-10-8-19(24)9-11-20)28-14-12-27(13-15-28)21-6-4-3-5-7-21/h8-11,18,21-22H,3-7,12-17H2,1-2H3,(H2,25,26,29) SCDAAZYFMZOQMT-UHFFFAOYSA-N 50162394 1-(4-Chloro-phenyl)-3-[2-(4-cyclohexyl-piperazin-1-yl)-4-methyl-pentyl]-urea::CHEMBL193916 C-C chemokine receptor type 3 Homo sapiens 429.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162394&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400977 104048560 CHEMBL193916 ZINC28523136 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299552 COc1ccc(cc1)C(CNC(=O)Nc1ccc(F)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H35FN4O2/c1-33-24-13-7-20(8-14-24)25(19-28-26(32)29-22-11-9-21(27)10-12-22)31-17-15-30(16-18-31)23-5-3-2-4-6-23/h7-14,23,25H,2-6,15-19H2,1H3,(H2,28,29,32) TYSJJFAHSWGDED-UHFFFAOYSA-N 50162395 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-3-(4-fluoro-phenyl)-urea::CHEMBL192162 C-C chemokine receptor type 3 Homo sapiens 1030 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162395&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401055 104048561 CHEMBL192162 ZINC28520641 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299553 CC(C)(C)c1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C33H50N4O/c1-32(2,3)26-14-12-25(13-15-26)30(37-22-20-36(21-23-37)29-10-8-7-9-11-29)24-34-31(38)35-28-18-16-27(17-19-28)33(4,5)6/h12-19,29-30H,7-11,20-24H2,1-6H3,(H2,34,35,38) SKFPWOHYDHHLKH-UHFFFAOYSA-N 50162403 1-(4-tert-Butyl-phenyl)-3-[2-(4-tert-butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-urea::CHEMBL365584 C-C chemokine receptor type 3 Homo sapiens 2050 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162403&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400954 104048569 CHEMBL365584 ZINC28476786 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299554 CN(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C29H41F3N4/c1-34(2)26-14-8-23(9-15-26)16-17-33-22-28(24-10-12-25(13-11-24)29(30,31)32)36-20-18-35(19-21-36)27-6-4-3-5-7-27/h8-15,27-28,33H,3-7,16-22H2,1-2H3 FWSPPCXTUQYBKS-UHFFFAOYSA-N 50162400 (4-{2-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethylamino]-ethyl}-phenyl)-dimethyl-amine::CHEMBL193975 C-C chemokine receptor type 3 Homo sapiens 1080 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162400&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401062 104048566 CHEMBL193975 ZINC28522868 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299555 Cc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C28H38F3N3/c1-22-7-9-23(10-8-22)15-16-32-21-27(24-11-13-25(14-12-24)28(29,30)31)34-19-17-33(18-20-34)26-5-3-2-4-6-26/h7-14,26-27,32H,2-6,15-21H2,1H3 RNQHDIZVKYTQNH-UHFFFAOYSA-N 50162398 CHEMBL193828::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-(2-p-tolyl-ethyl)-amine C-C chemokine receptor type 3 Homo sapiens 545.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162398&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401048 104048564 CHEMBL193828 ZINC28523732 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299556 CN(C)c1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H37Cl2N5O/c1-32(2)24-10-8-20(9-11-24)26(19-30-27(35)31-23-17-21(28)16-22(29)18-23)34-14-12-33(13-15-34)25-6-4-3-5-7-25/h8-11,16-18,25-26H,3-7,12-15,19H2,1-2H3,(H2,30,31,35) ZOHITTAFJLGDNH-UHFFFAOYSA-N 50162397 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-dimethylamino-phenyl)-ethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL191696 C-C chemokine receptor type 3 Homo sapiens 987 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162397&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401176 104048563 CHEMBL191696 ZINC28520438 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299557 COc1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H39N3O/c1-31-26-14-12-24(13-15-26)27(22-28-17-16-23-8-4-2-5-9-23)30-20-18-29(19-21-30)25-10-6-3-7-11-25/h2,4-5,8-9,12-15,25,27-28H,3,6-7,10-11,16-22H2,1H3 LSYZYRQQVQHRFA-UHFFFAOYSA-N 50162401 CHEMBL372496::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-phenethyl-amine C-C chemokine receptor type 3 Homo sapiens 1040 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162401&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401227 104048567 CHEMBL372496 ZINC28523029 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299558 Clc1cc(Cl)cc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)c1 InChI=1S/C25H32Cl2N4O/c26-20-15-21(27)17-22(16-20)29-25(32)28-18-24(19-7-3-1-4-8-19)31-13-11-30(12-14-31)23-9-5-2-6-10-23/h1,3-4,7-8,15-17,23-24H,2,5-6,9-14,18H2,(H2,28,29,32) NAQUXUSUTYLYRW-UHFFFAOYSA-N 50162402 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL193931 C-C chemokine receptor type 3 Homo sapiens 1250 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162402&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400992 104048568 CHEMBL193931 ZINC28523579 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299559 CN1CCN(CC1)C(CNCCc1ccc(C)cc1)c1ccccc1 InChI=1S/C22H31N3/c1-19-8-10-20(11-9-19)12-13-23-18-22(21-6-4-3-5-7-21)25-16-14-24(2)15-17-25/h3-11,22-23H,12-18H2,1-2H3 DCIFHYZQBNVLIP-UHFFFAOYSA-N 50162399 CHEMBL425377::[2-(4-Methyl-piperazin-1-yl)-2-phenyl-ethyl]-(2-p-tolyl-ethyl)-amine C-C chemokine receptor type 3 Homo sapiens 11600 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162399&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400972 104048565 CHEMBL425377 ZINC28523399 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299560 COc1ccc(cc1)C(CNCCc1ccc(F)cc1)N1CCN(C)CC1 InChI=1S/C22H30FN3O/c1-25-13-15-26(16-14-25)22(19-5-9-21(27-2)10-6-19)17-24-12-11-18-3-7-20(23)8-4-18/h3-10,22,24H,11-17H2,1-2H3 FWIVRAQPMXHCNZ-UHFFFAOYSA-N 50162404 CHEMBL195197::[2-(4-Fluoro-phenyl)-ethyl]-[2-(4-methoxy-phenyl)-2-(4-methyl-piperazin-1-yl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 11700 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162404&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401053 104048570 CHEMBL195197 ZINC28523242 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299525 FC(F)(F)c1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H36F3N3/c28-27(29,30)24-13-11-23(12-14-24)26(21-31-16-15-22-7-3-1-4-8-22)33-19-17-32(18-20-33)25-9-5-2-6-10-25/h1,3-4,7-8,11-14,25-26,31H,2,5-6,9-10,15-21H2 BRYYHLGRUGDGBG-UHFFFAOYSA-N 50162367 CHEMBL194135::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-phenethyl-amine C-C chemokine receptor type 3 Homo sapiens 484.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162367&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401146 104048533 CHEMBL194135 ZINC28523050 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299561 FC(F)(F)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H33F3N4O/c27-26(28,29)21-13-11-20(12-14-21)24(19-30-25(34)31-22-7-3-1-4-8-22)33-17-15-32(16-18-33)23-9-5-2-6-10-23/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15-19H2,(H2,30,31,34) AHHOJFQACICXEL-UHFFFAOYSA-N 50162410 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-phenyl-urea::CHEMBL195291 C-C chemokine receptor type 3 Homo sapiens 479 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162410&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401037 104048576 CHEMBL195291 ZINC28522343 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299562 COc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C31H47N3O/c1-31(2,3)27-14-12-26(13-15-27)30(24-32-19-18-25-10-16-29(35-4)17-11-25)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h10-17,28,30,32H,5-9,18-24H2,1-4H3 FDSAKRKDLPNMLT-UHFFFAOYSA-N 50162411 CHEMBL194161::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-[2-(4-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 346 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162411&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401154 104048577 CHEMBL194161 ZINC28522930 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299563 COc1ccccc1CCNCC(N1CCN(CC1)c1ccccc1)c1ccc(cc1)C(C)(C)C InChI=1S/C31H41N3O/c1-31(2,3)27-16-14-25(15-17-27)29(24-32-19-18-26-10-8-9-13-30(26)35-4)34-22-20-33(21-23-34)28-11-6-5-7-12-28/h5-17,29,32H,18-24H2,1-4H3 BIKFSSUQPVPOTQ-UHFFFAOYSA-N 50162407 CHEMBL195657::[2-(4-tert-Butyl-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-[2-(2-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 488.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162407&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401256 104048573 CHEMBL195657 ZINC28522478 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299564 Clc1cc(Cl)cc(CC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)c1 InChI=1S/C26H33Cl2N3O/c27-22-15-20(16-23(28)18-22)17-26(32)29-19-25(21-7-3-1-4-8-21)31-13-11-30(12-14-31)24-9-5-2-6-10-24/h1,3-4,7-8,15-16,18,24-25H,2,5-6,9-14,17,19H2,(H,29,32) XZZHXQBAHUQDLK-UHFFFAOYSA-N 50162406 CHEMBL192384::N-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-2-(3,5-dichloro-phenyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 62500 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162406&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401069 104048572 CHEMBL192384 ZINC28478141 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299565 CC(C)CC(CNC(=O)Nc1cc(C)cc(C)c1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 InChI=1S/C25H34Cl2N4O/c1-17(2)11-22(16-28-25(32)29-20-13-18(3)12-19(4)14-20)31-9-7-30(8-10-31)21-5-6-23(26)24(27)15-21/h5-6,12-15,17,22H,7-11,16H2,1-4H3,(H2,28,29,32) LWHIDSSHJAZUCB-UHFFFAOYSA-N 50162405 1-{2-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl]-4-methyl-pentyl}-3-(3,5-dimethyl-phenyl)-urea::CHEMBL195202 C-C chemokine receptor type 3 Homo sapiens 313 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162405&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401182 104048571 CHEMBL195202 ZINC28522398 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299566 Cc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)cc1 InChI=1S/C32H40N4O/c1-25-12-18-29(19-13-25)34-32(37)33-24-31(28-16-14-27(15-17-28)26-8-4-2-5-9-26)36-22-20-35(21-23-36)30-10-6-3-7-11-30/h2,4-5,8-9,12-19,30-31H,3,6-7,10-11,20-24H2,1H3,(H2,33,34,37) LPGUJYWWRBKIOS-UHFFFAOYSA-N 50162412 1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-p-tolyl-urea::CHEMBL195610 C-C chemokine receptor type 3 Homo sapiens 316 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162412&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25056325 104048578 CHEMBL195610 ZINC28520977 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299567 COc1ccc(cc1)C(CNCCc1ccc(cc1)C(C)(C)C)N1CCN(CC1)C1CCCCC1 InChI=1S/C31H47N3O/c1-31(2,3)27-14-10-25(11-15-27)18-19-32-24-30(26-12-16-29(35-4)17-13-26)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h10-17,28,30,32H,5-9,18-24H2,1-4H3 YIAJMZYNKVFSCV-UHFFFAOYSA-N 50162409 CHEMBL191959::[2-(4-tert-Butyl-phenyl)-ethyl]-[2-(4-cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 629 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162409&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401110 104048575 CHEMBL191959 ZINC28520419 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299568 COc1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(C)(C)C)N1CCN(CC1)C1CCCCC1 InChI=1S/C30H44N4O2/c1-30(2,3)24-12-14-25(15-13-24)32-29(35)31-22-28(23-10-16-27(36-4)17-11-23)34-20-18-33(19-21-34)26-8-6-5-7-9-26/h10-17,26,28H,5-9,18-22H2,1-4H3,(H2,31,32,35) IWHKDPIAKYWOCM-UHFFFAOYSA-N 50162417 1-(4-tert-Butyl-phenyl)-3-[2-(4-cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-urea::CHEMBL194022 C-C chemokine receptor type 3 Homo sapiens 910.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162417&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401032 104048583 CHEMBL194022 ZINC28522972 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299569 FC(F)(F)c1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H32F6N4O/c28-26(29,30)20-8-6-19(7-9-20)24(37-16-14-36(15-17-37)23-4-2-1-3-5-23)18-34-25(38)35-22-12-10-21(11-13-22)27(31,32)33/h6-13,23-24H,1-5,14-18H2,(H2,34,35,38) FDCXFDPTGGDPPT-UHFFFAOYSA-N 50162416 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL194025 C-C chemokine receptor type 3 Homo sapiens 1310 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162416&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401202 104048582 CHEMBL194025 ZINC28522932 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299570 COc1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C28H41N3O/c1-23-8-10-24(11-9-23)16-17-29-22-28(25-12-14-27(32-2)15-13-25)31-20-18-30(19-21-31)26-6-4-3-5-7-26/h8-15,26,28-29H,3-7,16-22H2,1-2H3 ZZMPTQZANQVWEF-UHFFFAOYSA-N 50162419 CHEMBL193809::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-(2-p-tolyl-ethyl)-amine C-C chemokine receptor type 3 Homo sapiens 914.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162419&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401234 104048585 CHEMBL193809 ZINC28523903 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299571 COc1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H37Cl2N3O/c1-33-26-9-7-22(8-10-26)27(20-30-12-11-21-17-23(28)19-24(29)18-21)32-15-13-31(14-16-32)25-5-3-2-4-6-25/h7-10,17-19,25,27,30H,2-6,11-16,20H2,1H3 IVBOWJNCCCSGMB-UHFFFAOYSA-N 50162418 CHEMBL195671::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-[2-(3,5-dichloro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 62 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162418&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25056323 104048584 CHEMBL195671 ZINC28523973 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299572 COc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C28H38F3N3O/c1-35-26-13-7-22(8-14-26)15-16-32-21-27(23-9-11-24(12-10-23)28(29,30)31)34-19-17-33(18-20-34)25-5-3-2-4-6-25/h7-14,25,27,32H,2-6,15-21H2,1H3 JDANRXAKCVSJHD-UHFFFAOYSA-N 50162408 CHEMBL365806::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(4-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 477.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162408&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401175 104048574 CHEMBL365806 ZINC28520434 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299573 CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C29H42N4O/c1-29(2,3)24-16-14-23(15-17-24)27(22-30-28(34)31-25-10-6-4-7-11-25)33-20-18-32(19-21-33)26-12-8-5-9-13-26/h4,6-7,10-11,14-17,26-27H,5,8-9,12-13,18-22H2,1-3H3,(H2,30,31,34) ZJTXGBBFIYXPJP-UHFFFAOYSA-N 50162421 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-phenyl-urea::CHEMBL195427 C-C chemokine receptor type 3 Homo sapiens 1130 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162421&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401128 104048587 CHEMBL195427 ZINC28522228 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299574 CC(C)(C)c1ccc(cc1)C(CNC(=O)Cc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1 InChI=1S/C31H42F3N3O/c1-30(2,3)25-15-11-24(12-16-25)28(37-19-17-36(18-20-37)27-7-5-4-6-8-27)22-35-29(38)21-23-9-13-26(14-10-23)31(32,33)34/h9-16,27-28H,4-8,17-22H2,1-3H3,(H,35,38) MBGWRHXILCGPCT-UHFFFAOYSA-N 50162414 CHEMBL194943::N-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-2-(4-trifluoromethyl-phenyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 10300 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162414&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401192 104048580 CHEMBL194943 ZINC28523122 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299575 COc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C28H32F3N3O/c1-35-26-13-7-22(8-14-26)15-16-32-21-27(23-9-11-24(12-10-23)28(29,30)31)34-19-17-33(18-20-34)25-5-3-2-4-6-25/h2-14,27,32H,15-21H2,1H3 NKQKBALSOAMMEY-UHFFFAOYSA-N 50162413 CHEMBL427357::[2-(4-Methoxy-phenyl)-ethyl]-[2-(4-phenyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 393 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162413&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401088 104048579 CHEMBL427357 ZINC28523125 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299576 Cc1ccc(NC(=O)NCC(N2CCN(CC2)c2ccccc2)c2ccccc2)cc1 InChI=1S/C26H30N4O/c1-21-12-14-23(15-13-21)28-26(31)27-20-25(22-8-4-2-5-9-22)30-18-16-29(17-19-30)24-10-6-3-7-11-24/h2-15,25H,16-20H2,1H3,(H2,27,28,31) RMEABNGXSQNZGH-UHFFFAOYSA-N 50162423 1-[2-Phenyl-2-(4-phenyl-piperazin-1-yl)-ethyl]-3-p-tolyl-urea::CHEMBL192385 C-C chemokine receptor type 3 Homo sapiens 8020.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162423&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401070 104048589 CHEMBL192385 ZINC28478146 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299577 COc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)cc1 InChI=1S/C26H36N4O2/c1-32-24-14-12-22(13-15-24)28-26(31)27-20-25(21-8-4-2-5-9-21)30-18-16-29(17-19-30)23-10-6-3-7-11-23/h2,4-5,8-9,12-15,23,25H,3,6-7,10-11,16-20H2,1H3,(H2,27,28,31) OMRQJXNDCQSFIT-UHFFFAOYSA-N 50162415 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-3-(4-methoxy-phenyl)-urea::CHEMBL195533 C-C chemokine receptor type 3 Homo sapiens 9830.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162415&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400983 104048581 CHEMBL195533 ZINC28522335 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299578 CC(C)(C)c1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1 InChI=1S/C30H45N3/c1-30(2,3)27-16-14-26(15-17-27)29(24-31-19-18-25-10-6-4-7-11-25)33-22-20-32(21-23-33)28-12-8-5-9-13-28/h4,6-7,10-11,14-17,28-29,31H,5,8-9,12-13,18-24H2,1-3H3 BRLXSTZIVYPJNE-UHFFFAOYSA-N 50162425 CHEMBL365596::[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-phenethyl-amine C-C chemokine receptor type 3 Homo sapiens 350.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162425&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401206 104048591 CHEMBL365596 ZINC28523877 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299579 CC(C)CC(CNC(=O)Nc1ccc(C)cc1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 InChI=1S/C24H32Cl2N4O/c1-17(2)14-21(16-27-24(31)28-19-6-4-18(3)5-7-19)30-12-10-29(11-13-30)20-8-9-22(25)23(26)15-20/h4-9,15,17,21H,10-14,16H2,1-3H3,(H2,27,28,31) GZODQAPLJTZKMB-UHFFFAOYSA-N 50162424 1-{2-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl]-4-methyl-pentyl}-3-p-tolyl-urea::CHEMBL195495 C-C chemokine receptor type 3 Homo sapiens 179 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162424&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401047 104048590 CHEMBL195495 ZINC28522428 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299580 COc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C31H41N3O/c1-31(2,3)27-14-12-26(13-15-27)30(24-32-19-18-25-10-16-29(35-4)17-11-25)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h5-17,30,32H,18-24H2,1-4H3 XAPNZZKLQLISLW-UHFFFAOYSA-N 50162428 CHEMBL193633::[2-(4-tert-Butyl-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-[2-(4-methoxy-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 768.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162428&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400991 104048594 CHEMBL193633 ZINC28523730 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299581 Cc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C27H35F3N4O/c1-20-7-13-23(14-8-20)32-26(35)31-19-25(21-9-11-22(12-10-21)27(28,29)30)34-17-15-33(16-18-34)24-5-3-2-4-6-24/h7-14,24-25H,2-6,15-19H2,1H3,(H2,31,32,35) BLKAFNSEWMLWRN-UHFFFAOYSA-N 50162429 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-p-tolyl-urea::CHEMBL192751 C-C chemokine receptor type 3 Homo sapiens 1070 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162429&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400953 104048595 CHEMBL192751 ZINC28476780 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299582 COc1ccccc1CCNCC(N1CCN(CC1)c1ccccc1)c1ccccc1OC InChI=1S/C28H35N3O2/c1-32-27-14-8-6-10-23(27)16-17-29-22-26(25-13-7-9-15-28(25)33-2)31-20-18-30(19-21-31)24-11-4-3-5-12-24/h3-15,26,29H,16-22H2,1-2H3 JCIUJUGOJXTHOV-UHFFFAOYSA-N 50162430 CHEMBL363409::[2-(2-Methoxy-phenyl)-ethyl]-[2-(2-methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 1580 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162430&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401172 104048596 CHEMBL363409 ZINC28523987 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299583 COc1ccccc1NC(=O)NCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(F)(F)F InChI=1S/C27H35F3N4O2/c1-36-25-10-6-5-9-23(25)32-26(35)31-19-24(20-11-13-21(14-12-20)27(28,29)30)34-17-15-33(16-18-34)22-7-3-2-4-8-22/h5-6,9-14,22,24H,2-4,7-8,15-19H2,1H3,(H2,31,32,35) PJECWHFRADOJNA-UHFFFAOYSA-N 50162431 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-3-(2-methoxy-phenyl)-urea::CHEMBL373158 C-C chemokine receptor type 3 Homo sapiens 3650 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162431&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401248 104048597 CHEMBL373158 ZINC28523630 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299584 COc1ccccc1NC(=O)NCC(N1CCN(C)CC1)c1ccc(cc1)C(F)(F)F InChI=1S/C22H27F3N4O2/c1-28-11-13-29(14-12-28)19(16-7-9-17(10-8-16)22(23,24)25)15-26-21(30)27-18-5-3-4-6-20(18)31-2/h3-10,19H,11-15H2,1-2H3,(H2,26,27,30) ZEKFQPATDFGTGI-UHFFFAOYSA-N 50162427 1-(2-Methoxy-phenyl)-3-[2-(4-methyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-urea::CHEMBL193369 C-C chemokine receptor type 3 Homo sapiens 3350.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162427&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401160 104048593 CHEMBL193369 ZINC28523651 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299585 COc1ccc(cc1)C(CNC(=O)Cc1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C27H31N3O2/c1-32-25-14-12-23(13-15-25)26(21-28-27(31)20-22-8-4-2-5-9-22)30-18-16-29(17-19-30)24-10-6-3-7-11-24/h2-15,26H,16-21H2,1H3,(H,28,31) DSEDFCDPZCTTHR-UHFFFAOYSA-N 50162426 CHEMBL193818::N-[2-(4-Methoxy-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-2-phenyl-acetamide C-C chemokine receptor type 3 Homo sapiens 40200 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162426&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401189 104048592 CHEMBL193818 ZINC28523477 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299586 COc1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H35F3N4O2/c1-36-24-13-7-20(8-14-24)25(34-17-15-33(16-18-34)23-5-3-2-4-6-23)19-31-26(35)32-22-11-9-21(10-12-22)27(28,29)30/h7-14,23,25H,2-6,15-19H2,1H3,(H2,31,32,35) JOZOHPBCAIWMKA-UHFFFAOYSA-N 50162422 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL366231 C-C chemokine receptor type 3 Homo sapiens 1530 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162422&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400973 104048588 CHEMBL366231 ZINC28523053 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299587 COc1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C26H34Cl2N4O2/c1-34-24-9-7-19(8-10-24)25(18-29-26(33)30-22-16-20(27)15-21(28)17-22)32-13-11-31(12-14-32)23-5-3-2-4-6-23/h7-10,15-17,23,25H,2-6,11-14,18H2,1H3,(H2,29,30,33) XYDCBDBLPIJGQD-UHFFFAOYSA-N 50162433 1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-phenyl)-ethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL175547 C-C chemokine receptor type 3 Homo sapiens 830 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162433&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387847 104048599 CHEMBL175547 ZINC28113956 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299588 COc1ccccc1CC(=O)NCC(N1CCN(CC1)c1ccccc1)c1ccc(cc1)C(C)(C)C InChI=1S/C31H39N3O2/c1-31(2,3)26-16-14-24(15-17-26)28(23-32-30(35)22-25-10-8-9-13-29(25)36-4)34-20-18-33(19-21-34)27-11-6-5-7-12-27/h5-17,28H,18-23H2,1-4H3,(H,32,35) XHUQLKYVIKLURC-UHFFFAOYSA-N 50162434 CHEMBL372725::N-[2-(4-tert-Butyl-phenyl)-2-(4-phenyl-piperazin-1-yl)-ethyl]-2-(2-methoxy-phenyl)-acetamide C-C chemokine receptor type 3 Homo sapiens 8850.0 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162434&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400974 104048600 CHEMBL372725 ZINC28523055 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299589 COc1ccccc1C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1 InChI=1S/C27H37Cl2N3O/c1-33-27-10-6-5-9-25(27)26(20-30-12-11-21-17-22(28)19-23(29)18-21)32-15-13-31(14-16-32)24-7-3-2-4-8-24/h5-6,9-10,17-19,24,26,30H,2-4,7-8,11-16,20H2,1H3 VMFHCPVQZNTAEM-UHFFFAOYSA-N 50162432 CHEMBL364047::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(2-methoxy-phenyl)-ethyl]-[2-(3,5-dichloro-phenyl)-ethyl]-amine C-C chemokine receptor type 3 Homo sapiens 344 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162432&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401083 104048598 CHEMBL364047 ZINC28523638 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50299590 CN(C)c1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1 InChI=1S/C31H47N5O/c1-31(2,3)25-13-11-24(12-14-25)29(36-21-19-35(20-22-36)28-9-7-6-8-10-28)23-32-30(37)33-26-15-17-27(18-16-26)34(4)5/h11-18,28-29H,6-10,19-23H2,1-5H3,(H2,32,33,37) HEEKPFDTRBATOX-UHFFFAOYSA-N 50162420 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(4-dimethylamino-phenyl)-urea::CHEMBL195353 C-C chemokine receptor type 3 Homo sapiens 1720 ChEMBL 10.1021/jm040827u 10.7270/Q2KK9B8W 15743194 Vedani, A; Dobler, M; Dollinger, H; Hasselbach, KM; Birke, F; Lill, MA Biographics Laboratory 3R http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162420&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44400995 104048586 CHEMBL195353 ZINC28523419 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302207 CC(=O)c1cccc(NC(=O)Nc2ccccc2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H30FN3O2/c1-20(33)23-6-4-7-26(18-23)30-28(34)31-27-8-3-2-5-24(27)19-32-15-13-22(14-16-32)17-21-9-11-25(29)12-10-21/h2-12,18,22H,13-17,19H2,1H3,(H2,30,31,34) GFGVSPYXQBYZOT-UHFFFAOYSA-N 50117413 1-(3-Acetyl-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-phenyl}-urea::CHEMBL124317 C-C chemokine receptor type 3 Homo sapiens 125 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117413&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11037869 104010969 CHEMBL124317 ZINC13475799 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302210 Cn1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)n1 InChI=1S/C24H34FN5O/c1-29-14-12-23(28-29)27-24(31)26-22-7-3-2-6-20(22)17-30-13-4-5-19(16-30)15-18-8-10-21(25)11-9-18/h8-12,14,19-20,22H,2-7,13,15-17H2,1H3,(H2,26,27,28,31)/t19-,20-,22+/m0/s1 GGWUCCLVCATVGO-JAXLGGSGSA-N 50163637 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1-methyl-1H-pyrazol-3-yl)-urea::CHEMBL365732 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163637&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11373714 104049620 CHEMBL365732 ZINC13613349 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302220 COc1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C27H36FN3O2/c1-33-25-7-4-6-24(18-25)29-27(32)30-26-8-3-2-5-22(26)19-31-15-13-21(14-16-31)17-20-9-11-23(28)12-10-20/h4,6-7,9-12,18,21-22,26H,2-3,5,8,13-17,19H2,1H3,(H2,29,30,32) YLLQTYFPCPQMDK-UHFFFAOYSA-N 50163643 1-{2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-methoxy-phenyl)-urea::CHEMBL175502 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163643&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9868532 104049626 CHEMBL175502 ZINC28116238 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302224 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24+,27-/m1/s1 ASRDPULQBHFPGU-RWCIVJTCSA-N 50163645 1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[(R)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL370082 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163645&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11385766 104049628 CHEMBL370082 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302225 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(Br)cc3)C2)cc1 InChI=1S/C26H33BrFN3O/c27-22-9-13-24(14-10-22)29-26(32)30-25-6-2-1-5-21(25)18-31-15-3-4-20(17-31)16-19-7-11-23(28)12-8-19/h7-14,20-21,25H,1-6,15-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 XOLRUKHPGCIPJW-STWLZBDKSA-N 50163646 1-(4-Bromo-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193442 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163646&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11179592 104049629 CHEMBL193442 ZINC13613294 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302227 Cn1nnnc1-c1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-10-14-25(15-11-22)30-28(37)31-26-7-3-2-6-23(26)19-36-16-4-5-21(18-36)17-20-8-12-24(29)13-9-20/h8-15,21,23,26H,2-7,16-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 LWUHFNIVZIRWQA-RZPFDVGOSA-N 50163635 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[4-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL277131 C-C chemokine receptor type 3 Homo sapiens 0.250000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163635&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11398022 104049618 CHEMBL277131 ZINC13613372 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302228 CC1C2C=CC(NC(=O)N[C@@H]3CCCC[C@H]3CN3CCC[C@@H](Cc4ccc(F)cc4)C3)=CC2N=C1C InChI=1S/C30H41FN4O/c1-20-21(2)32-29-17-26(13-14-27(20)29)33-30(36)34-28-8-4-3-7-24(28)19-35-15-5-6-23(18-35)16-22-9-11-25(31)12-10-22/h9-14,17,20,23-24,27-29H,3-8,15-16,18-19H2,1-2H3,(H2,33,34,36)/t20?,23-,24-,27?,28+,29?/m0/s1 RQDMJARGXCFCAW-GAEPSJKYSA-N 50163647 1-(2,3-Dimethyl-3a,7a-dihydro-1H-indol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL365176 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163647&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936716 104049630 CHEMBL365176 ZINC36352009 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302231 COc1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H36FN3O2/c1-33-26-11-5-4-10-25(26)30-27(32)29-24-9-3-2-8-22(24)19-31-16-6-7-21(18-31)17-20-12-14-23(28)15-13-20/h4-5,10-15,21-22,24H,2-3,6-9,16-19H2,1H3,(H2,29,30,32)/t21-,22-,24+/m0/s1 UKGNFGQNYLRGJL-WPFOTENUSA-N 50163651 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-methoxy-phenyl)-urea::CHEMBL175634 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163651&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11363005 104049634 CHEMBL175634 ZINC13613259 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302232 Cc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1F InChI=1S/C27H35F2N3O/c1-19-8-13-24(16-25(19)29)30-27(33)31-26-7-3-2-6-22(26)18-32-14-4-5-21(17-32)15-20-9-11-23(28)12-10-20/h8-13,16,21-22,26H,2-7,14-15,17-18H2,1H3,(H2,30,31,33)/t21-,22-,26+/m0/s1 MQYFAGPXNWMFSN-AOJNWGRGSA-N 50163648 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-fluoro-4-methyl-phenyl)-urea::CHEMBL363166 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163648&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11442439 104049631 CHEMBL363166 ZINC13613274 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302239 Cn1nnnc1-c1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)24-9-3-5-11-26(24)31-28(37)30-25-10-4-2-8-22(25)19-36-16-6-7-21(18-36)17-20-12-14-23(29)15-13-20/h3,5,9,11-15,21-22,25H,2,4,6-8,10,16-19H2,1H3,(H2,30,31,37)/t21-,22-,25+/m0/s1 UNTXMOHFIXMRMR-WRALFONMSA-N 50163652 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[2-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL364508 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163652&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11156406 104049635 CHEMBL364508 ZINC13613365 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302244 COc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 InChI=1S/C27H36FN3O2/c1-33-25-14-12-24(13-15-25)29-27(32)30-26-7-3-2-6-22(26)19-31-16-4-5-21(18-31)17-20-8-10-23(28)11-9-20/h8-15,21-22,26H,2-7,16-19H2,1H3,(H2,29,30,32)/t21-,22-,26+/m0/s1 OEKONQSOWUDFGV-AOJNWGRGSA-N 50163632 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methoxy-phenyl)-urea::CHEMBL194601 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163632&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11363006 104049615 CHEMBL194601 ZINC13613262 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302246 CC(=O)c1cccc(NC(=O)NN2CCCCC2Cc2ccc(F)cc2)c1 InChI=1S/C21H24FN3O2/c1-15(26)17-5-4-6-19(14-17)23-21(27)24-25-12-3-2-7-20(25)13-16-8-10-18(22)11-9-16/h4-6,8-11,14,20H,2-3,7,12-13H2,1H3,(H2,23,24,27) SOEZEWJTMGDYDZ-UHFFFAOYSA-N 50163638 1-(3-Acetyl-phenyl)-3-[2-(4-fluoro-benzyl)-piperidin-1-yl]-urea::CHEMBL368683 C-C chemokine receptor type 3 Homo sapiens 71 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163638&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387842 104049621 CHEMBL368683 ZINC28112350 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302248 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(F)cc3)C2)cc1 InChI=1S/C26H33F2N3O/c27-22-9-7-19(8-10-22)16-20-4-3-15-31(17-20)18-21-5-1-2-6-25(21)30-26(32)29-24-13-11-23(28)12-14-24/h7-14,20-21,25H,1-6,15-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 NKRJCSZTCFOFKV-STWLZBDKSA-N 50163654 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-fluoro-phenyl)-urea::CHEMBL194141 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163654&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11316656 104049637 CHEMBL194141 ZINC03976344 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302251 Cc1nnnn1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-20-32-33-34-36(20)26-9-4-8-25(17-26)30-28(37)31-27-10-3-2-7-23(27)19-35-15-5-6-22(18-35)16-21-11-13-24(29)14-12-21/h4,8-9,11-14,17,22-23,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t22-,23-,27+/m0/s1 QLTHBTHVYYXPHB-VMODYCNZSA-N 50163656 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(5-methyl-tetrazol-1-yl)-phenyl]-urea::CHEMBL195555 C-C chemokine receptor type 3 Homo sapiens 0.100000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163656&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11454941 104049639 CHEMBL195555 ZINC13613361 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308773 Cc1ccccc1CC(=O)NCC1CCCN(C1)C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H35Cl2N3O/c1-20-5-2-3-7-23(20)16-27(33)30-17-22-6-4-12-32(19-22)24-10-13-31(14-11-24)18-21-8-9-25(28)26(29)15-21/h2-3,5,7-9,15,22,24H,4,6,10-14,16-19H2,1H3,(H,30,33) SSLBLYODMSIXSC-UHFFFAOYSA-N 50167433 CHEMBL189917::N-[1'-(3,4-Dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-2-o-tolyl-acetamide C-C chemokine receptor type 3 Homo sapiens 86 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167433&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399407 104052668 CHEMBL189917 ZINC28471825 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308774 COc1ccccc1C(=O)NCC1CCCN(C1)C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H33Cl2N3O2/c1-33-25-7-3-2-6-22(25)26(32)29-16-20-5-4-12-31(18-20)21-10-13-30(14-11-21)17-19-8-9-23(27)24(28)15-19/h2-3,6-9,15,20-21H,4-5,10-14,16-18H2,1H3,(H,29,32) NWCZSBYBGHIZGJ-UHFFFAOYSA-N 50167434 CHEMBL190646::N-[1'-(3,4-Dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-2-methoxy-benzamide C-C chemokine receptor type 3 Homo sapiens 92 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167434&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399442 104052669 CHEMBL190646 ZINC28469859 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308775 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3cccc4[nH]ccc34)C2)cc1Cl InChI=1S/C27H32Cl2N4O/c28-24-7-6-19(15-25(24)29)17-32-13-9-21(10-14-32)33-12-2-3-20(18-33)16-31-27(34)23-4-1-5-26-22(23)8-11-30-26/h1,4-8,11,15,20-21,30H,2-3,9-10,12-14,16-18H2,(H,31,34) FTRTZQXKLFEYED-UHFFFAOYSA-N 50167435 1H-Indole-4-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide::CHEMBL425548 C-C chemokine receptor type 3 Homo sapiens 36 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167435&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399482 104052670 CHEMBL425548 ZINC28472292 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308776 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-7-5-20(15-26(25)30)18-33-13-9-24(10-14-33)34-12-2-3-21(19-34)17-32-28(35)23-6-8-27-22(16-23)4-1-11-31-27/h1,4-8,11,15-16,21,24H,2-3,9-10,12-14,17-19H2,(H,32,35) NKESGSSPZVLTKI-UHFFFAOYSA-N 50167436 CHEMBL426089::Quinoline-6-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 136 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167436&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399469 104052671 CHEMBL426089 ZINC28474848 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308777 CC(=O)NCC1CCCN(C1)C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C20H29Cl2N3O/c1-15(26)23-12-17-3-2-8-25(14-17)18-6-9-24(10-7-18)13-16-4-5-19(21)20(22)11-16/h4-5,11,17-18H,2-3,6-10,12-14H2,1H3,(H,23,26) WUZUVCAFDHJUGI-UHFFFAOYSA-N 50167437 CHEMBL189158::N-[1'-(3,4-Dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-acetamide C-C chemokine receptor type 3 Homo sapiens 533 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167437&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399552 104052672 CHEMBL189158 ZINC28472081 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308778 CC1CN(Cc2ccc(Cl)c(Cl)c2)CCC1N1CCCC(CNC(=O)c2ccc3ncccc3c2)C1 InChI=1S/C29H34Cl2N4O/c1-20-17-34(18-21-6-8-25(30)26(31)14-21)13-10-28(20)35-12-3-4-22(19-35)16-33-29(36)24-7-9-27-23(15-24)5-2-11-32-27/h2,5-9,11,14-15,20,22,28H,3-4,10,12-13,16-19H2,1H3,(H,33,36) RPJZHDKOKSGFON-UHFFFAOYSA-N 50167438 CHEMBL191464::Quinoline-6-carboxylic acid [1'-(3,4-dichloro-benzyl)-3'-methyl-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 7.3 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167438&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399303 104052673 CHEMBL191464 ZINC36352001 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308779 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3nccc4ccccc34)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-8-7-20(16-26(25)30)18-33-14-10-23(11-15-33)34-13-3-4-21(19-34)17-32-28(35)27-24-6-2-1-5-22(24)9-12-31-27/h1-2,5-9,12,16,21,23H,3-4,10-11,13-15,17-19H2,(H,32,35) FYWJICYTASRDFO-UHFFFAOYSA-N 50167439 CHEMBL189206::Isoquinoline-1-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 34 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167439&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399272 104052674 CHEMBL189206 ZINC28472496 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308780 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3cnnc4ccccc34)C2)cc1Cl InChI=1S/C27H31Cl2N5O/c28-24-8-7-19(14-25(24)29)17-33-12-9-21(10-13-33)34-11-3-4-20(18-34)15-30-27(35)23-16-31-32-26-6-2-1-5-22(23)26/h1-2,5-8,14,16,20-21H,3-4,9-13,15,17-18H2,(H,30,35) QNOFODRHUMZNBU-UHFFFAOYSA-N 50167440 CHEMBL190048::Cinnoline-4-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 99 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167440&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399479 104052675 CHEMBL190048 ZINC28471837 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308781 CC(N1CCC(CC1)N1CCCC(CNC(=O)c2ccc3ncccc3c2)C1)c1ccc(Cl)c(Cl)c1 InChI=1S/C29H34Cl2N4O/c1-20(22-6-8-26(30)27(31)17-22)34-14-10-25(11-15-34)35-13-3-4-21(19-35)18-33-29(36)24-7-9-28-23(16-24)5-2-12-32-28/h2,5-9,12,16-17,20-21,25H,3-4,10-11,13-15,18-19H2,1H3,(H,33,36) WCKZXUZPEYGEII-UHFFFAOYSA-N 50167444 CHEMBL192757::Quinoline-6-carboxylic acid {1'-[1-(3,4-dichloro-phenyl)-ethyl]-[1,4']bipiperidinyl-3-ylmethyl}-amide C-C chemokine receptor type 3 Homo sapiens 74.3 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399332 104052679 CHEMBL192757 ZINC36352003 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308782 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4[nH]ccc4c3)C2)cc1Cl InChI=1S/C27H32Cl2N4O/c28-24-5-3-19(14-25(24)29)17-32-12-8-23(9-13-32)33-11-1-2-20(18-33)16-31-27(34)22-4-6-26-21(15-22)7-10-30-26/h3-7,10,14-15,20,23,30H,1-2,8-9,11-13,16-18H2,(H,31,34) MVBQPHOIQWJEQS-UHFFFAOYSA-N 50167442 1H-Indole-5-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide::CHEMBL190436 C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167442&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399385 104052677 CHEMBL190436 ZINC28470481 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308783 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccnc4ccccc34)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-8-7-20(16-26(25)30)18-33-14-10-22(11-15-33)34-13-3-4-21(19-34)17-32-28(35)24-9-12-31-27-6-2-1-5-23(24)27/h1-2,5-9,12,16,21-22H,3-4,10-11,13-15,17-19H2,(H,32,35) KBCNGWODBYJUSG-UHFFFAOYSA-N 50167441 CHEMBL190852::Quinoline-4-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 80 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167441&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399567 104052676 CHEMBL190852 ZINC28465537 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308784 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3cccc4ccccc34)C2)cc1Cl InChI=1S/C29H33Cl2N3O/c30-27-11-10-21(17-28(27)31)19-33-15-12-24(13-16-33)34-14-4-5-22(20-34)18-32-29(35)26-9-3-7-23-6-1-2-8-25(23)26/h1-3,6-11,17,22,24H,4-5,12-16,18-20H2,(H,32,35) HWKKZBCQXGBFOY-UHFFFAOYSA-N 50167445 CHEMBL372868::Naphthalene-1-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 58 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167445&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399524 104052680 CHEMBL372868 ZINC28474377 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308785 Clc1ccc(Cl)c(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)c1 InChI=1S/C28H32Cl2N4O/c29-24-6-7-26(30)23(16-24)19-33-13-9-25(10-14-33)34-12-2-3-20(18-34)17-32-28(35)22-5-8-27-21(15-22)4-1-11-31-27/h1,4-8,11,15-16,20,25H,2-3,9-10,12-14,17-19H2,(H,32,35) QCVWQWXJPXRDNC-UHFFFAOYSA-N 50167443 CHEMBL192584::Quinoline-6-carboxylic acid [1'-(2,5-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 391.0 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167443&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399443 104052678 CHEMBL192584 ZINC28476840 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308786 Cc1ccccc1C(=O)NCC1CCCN(C1)C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H33Cl2N3O/c1-19-5-2-3-7-23(19)26(32)29-16-21-6-4-12-31(18-21)22-10-13-30(14-11-22)17-20-8-9-24(27)25(28)15-20/h2-3,5,7-9,15,21-22H,4,6,10-14,16-18H2,1H3,(H,29,32) UBDILVCTGRHAIK-UHFFFAOYSA-N 50167447 CHEMBL187779::N-[1'-(3,4-Dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-2-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399368 104052682 CHEMBL187779 ZINC28465165 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308787 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)C3CCCCC3)C2)cc1Cl InChI=1S/C25H37Cl2N3O/c26-23-9-8-19(15-24(23)27)17-29-13-10-22(11-14-29)30-12-4-5-20(18-30)16-28-25(31)21-6-2-1-3-7-21/h8-9,15,20-22H,1-7,10-14,16-18H2,(H,28,31) WILUNEYZEWUFIC-UHFFFAOYSA-N 50167446 CHEMBL191418::Cyclohexanecarboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 107 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167446&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399573 104052681 CHEMBL191418 ZINC28468148 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308788 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)cc1 InChI=1S/C28H33ClN4O/c29-25-8-5-21(6-9-25)19-32-15-11-26(12-16-32)33-14-2-3-22(20-33)18-31-28(34)24-7-10-27-23(17-24)4-1-13-30-27/h1,4-10,13,17,22,26H,2-3,11-12,14-16,18-20H2,(H,31,34) CGQOZPVLKVIFSO-UHFFFAOYSA-N 50167448 CHEMBL190362::Quinoline-6-carboxylic acid [1'-(4-chloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 95 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399537 104052683 CHEMBL190362 ZINC28472183 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308789 Clc1cc(Cl)cc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)c1 InChI=1S/C28H32Cl2N4O/c29-24-13-21(14-25(30)16-24)18-33-11-7-26(8-12-33)34-10-2-3-20(19-34)17-32-28(35)23-5-6-27-22(15-23)4-1-9-31-27/h1,4-6,9,13-16,20,26H,2-3,7-8,10-12,17-19H2,(H,32,35) ITZBNMYCADUWJP-UHFFFAOYSA-N 50167450 CHEMBL190894::Quinoline-6-carboxylic acid [1'-(3,5-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 398 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167450&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399574 104052685 CHEMBL190894 ZINC28468439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308790 Clc1ccc(CC(=O)N2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)cc1Cl InChI=1S/C29H32Cl2N4O2/c30-25-7-5-20(15-26(25)31)16-28(36)34-13-9-24(10-14-34)35-12-2-3-21(19-35)18-33-29(37)23-6-8-27-22(17-23)4-1-11-32-27/h1,4-8,11,15,17,21,24H,2-3,9-10,12-14,16,18-19H2,(H,33,37) LISDALNKNJFZIL-UHFFFAOYSA-N 50167451 CHEMBL190312::Quinoline-6-carboxylic acid {1'-[2-(3,4-dichloro-phenyl)-acetyl]-[1,4']bipiperidinyl-3-ylmethyl}-amide C-C chemokine receptor type 3 Homo sapiens 767 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399290 104052686 CHEMBL190312 ZINC28472100 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308791 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ccccc4c3)C2)cc1Cl InChI=1S/C29H33Cl2N3O/c30-27-10-7-21(16-28(27)31)19-33-14-11-26(12-15-33)34-13-3-4-22(20-34)18-32-29(35)25-9-8-23-5-1-2-6-24(23)17-25/h1-2,5-10,16-17,22,26H,3-4,11-15,18-20H2,(H,32,35) DKULALWWMCGWHM-UHFFFAOYSA-N 50167449 CHEMBL366199::Naphthalene-2-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 48 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167449&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399331 104052684 CHEMBL366199 ZINC28474822 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308792 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-7-5-20(15-26(25)30)18-33-13-9-24(10-14-33)34-12-2-3-21(19-34)17-32-28(35)23-6-8-27-22(16-23)4-1-11-31-27/h1,4-8,11,15-16,21,24H,2-3,9-10,12-14,17-19H2,(H,32,35) NKESGSSPZVLTKI-UHFFFAOYSA-N 50167436 CHEMBL426089::Quinoline-6-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167436&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399469 104052671 CHEMBL426089 ZINC28474848 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308793 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3cccc4cccnc34)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-9-8-20(16-26(25)30)18-33-14-10-23(11-15-33)34-13-3-4-21(19-34)17-32-28(35)24-7-1-5-22-6-2-12-31-27(22)24/h1-2,5-9,12,16,21,23H,3-4,10-11,13-15,17-19H2,(H,32,35) BJNIWMAHXDJWJS-UHFFFAOYSA-N 50167454 CHEMBL193354::Quinoline-8-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167454&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11540776 104052689 CHEMBL193354 ZINC28473851 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308794 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4nc[nH]c4c3)C2)cc1Cl InChI=1S/C26H31Cl2N5O/c27-22-5-3-18(12-23(22)28)15-32-10-7-21(8-11-32)33-9-1-2-19(16-33)14-29-26(34)20-4-6-24-25(13-20)31-17-30-24/h3-6,12-13,17,19,21H,1-2,7-11,14-16H2,(H,29,34)(H,30,31) NJDZPWMNEMKDBB-UHFFFAOYSA-N 50167452 1H-Benzoimidazole-5-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide::CHEMBL366143 C-C chemokine receptor type 3 Homo sapiens 47 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167452&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399389 104052687 CHEMBL366143 ZINC28470501 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308795 CC1(CCN(Cc2ccc(Cl)c(Cl)c2)CC1)N1CCCC(CNC(=O)c2ccc3ncccc3c2)C1 InChI=1S/C29H34Cl2N4O/c1-29(10-14-34(15-11-29)19-21-6-8-25(30)26(31)16-21)35-13-3-4-22(20-35)18-33-28(36)24-7-9-27-23(17-24)5-2-12-32-27/h2,5-9,12,16-17,22H,3-4,10-11,13-15,18-20H2,1H3,(H,33,36) UXBPEIIOVGWXKR-UHFFFAOYSA-N 50167455 CHEMBL190149::Quinoline-6-carboxylic acid [1'-(3,4-dichloro-benzyl)-4'-methyl-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167455&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399395 104052690 CHEMBL190149 ZINC28470618 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308796 Clc1ccc(CN2CCC(CC2)N2CCCC(CNC(=O)c3cccc4cccnc34)C2)cc1Cl InChI=1S/C28H32Cl2N4O/c29-25-9-8-20(16-26(25)30)18-33-14-10-23(11-15-33)34-13-3-4-21(19-34)17-32-28(35)24-7-1-5-22-6-2-12-31-27(22)24/h1-2,5-9,12,16,21,23H,3-4,10-11,13-15,17-19H2,(H,32,35) BJNIWMAHXDJWJS-UHFFFAOYSA-N 50167454 CHEMBL193354::Quinoline-8-carboxylic acid [1'-(3,4-dichloro-benzyl)-[1,4']bipiperidinyl-3-ylmethyl]-amide C-C chemokine receptor type 3 Homo sapiens 30.0 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167454&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11540776 104052689 CHEMBL193354 ZINC28473851 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50308797 Clc1ccc(CCN2CCC(CC2)N2CCCC(CNC(=O)c3ccc4ncccc4c3)C2)cc1Cl InChI=1S/C29H34Cl2N4O/c30-26-7-5-21(17-27(26)31)9-14-34-15-10-25(11-16-34)35-13-2-3-22(20-35)19-33-29(36)24-6-8-28-23(18-24)4-1-12-32-28/h1,4-8,12,17-18,22,25H,2-3,9-11,13-16,19-20H2,(H,33,36) YCGKTGCKPZIUKH-UHFFFAOYSA-N 50167453 CHEMBL189680::Quinoline-6-carboxylic acid {1'-[2-(3,4-dichloro-phenyl)-ethyl]-[1,4']bipiperidinyl-3-ylmethyl}-amide C-C chemokine receptor type 3 Homo sapiens 180 ChEMBL 10.1016/j.bmcl.2005.04.054 10.7270/Q23T9GRW 15908209 Ting, PC; Umland, SP; Aslanian, R; Cao, J; Garlisi, CG; Huang, Y; Jakway, J; Liu, Z; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44399538 104052688 CHEMBL189680 ZINC28471855 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302255 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C28H37N3O2/c1-21(32)24-11-7-12-26(19-24)29-28(33)30-27-13-6-5-10-25(27)20-31-16-14-23(15-17-31)18-22-8-3-2-4-9-22/h2-4,7-9,11-12,19,23,25,27H,5-6,10,13-18,20H2,1H3,(H2,29,30,33)/t25-,27+/m0/s1 TUWGKLBUZJCNKG-AHKZPQOWSA-N 50163657 1-(3-Acetyl-phenyl)-3-[(1R,2S)-2-(4-benzyl-piperidin-1-ylmethyl)-cyclohexyl]-urea::CHEMBL369073 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163657&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387856 104049640 CHEMBL369073 ZINC28111797 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302257 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302263 Fc1ccc(CC2CCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C27H33FN4O/c28-24-10-8-20(9-11-24)16-21-12-14-32(15-13-21)19-23-5-1-2-7-26(23)31-27(33)30-25-6-3-4-22(17-25)18-29/h3-4,6,8-11,17,21,23,26H,1-2,5,7,12-16,19H2,(H2,30,31,33)/t23-,26+/m0/s1 ODVYSSIPDMNFIA-JYFHCDHNSA-N 50163658 1-(3-Cyano-phenyl)-3-{(1R,2S)-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL362465 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163658&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387837 104049641 CHEMBL362465 ZINC28117898 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302265 Fc1ccc(CC2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ncc4c3)C2)cc1 InChI=1S/C27H34FN5O/c28-23-9-7-19(8-10-23)14-20-4-3-13-33(17-20)18-21-5-1-2-6-25(21)31-27(34)30-24-11-12-26-22(15-24)16-29-32-26/h7-12,15-16,20-21,25H,1-6,13-14,17-18H2,(H,29,32)(H2,30,31,34)/t20?,21-,25+/m0/s1 MLPROCBAZKTJHS-FWDVVIQXSA-N 50163659 1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indazol-5-yl)-urea::CHEMBL363373 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163659&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401561 104049642 CHEMBL363373 ZINC28523389 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302272 CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-4-2-5-23(17-21)27-24(30)26-12-3-13-28-14-10-20(11-15-28)16-19-6-8-22(25)9-7-19/h2,4-9,17,20H,3,10-16H2,1H3,(H2,26,27,30) JSUGTZOUOKXRQN-UHFFFAOYSA-N 50115023 1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295832 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115023&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393282 104009011 CHEMBL295832 ZINC13443505 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302274 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m0/s1 FDDSQKZQCHXOJV-FQEVSTJZSA-N 50142448 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea::1-(3-Acetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46905 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290039 104031829 CHEMBL46905 ZINC13613375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302279 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)NC3CC=C(C(=C3)C#N)n3cccn3)C2)cc1 InChI=1S/C30H37FN6O/c31-26-10-8-22(9-11-26)17-23-5-3-15-36(20-23)21-24-6-1-2-7-28(24)35-30(38)34-27-12-13-29(25(18-27)19-32)37-16-4-14-33-37/h4,8-11,13-14,16,18,23-24,27-28H,1-3,5-7,12,15,17,20-21H2,(H2,34,35,38)/t23-,24-,27?,28+/m0/s1 QPBTXFXXYZMNDD-KYTFRPSZSA-N 50163644 1-(3-Cyano-4-pyrazol-1-yl-cyclohexa-2,4-dienyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL373347 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163644&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401123 104049627 CHEMBL373347 ZINC36352005 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302283 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-6-4-7-26(18-23)30-28(34)31-27-8-3-2-5-24(27)19-32-15-13-22(14-16-32)17-21-9-11-25(29)12-10-21/h4,6-7,9-12,18,22,24,27H,2-3,5,8,13-17,19H2,1H3,(H2,30,31,34)/t24-,27+/m0/s1 KUOOPYAWZGYOPB-RPLLCQBOSA-N 50163639 1-(3-Acetyl-phenyl)-3-{(1R,2S)-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL428881 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163639&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11465468 104049622 CHEMBL428881 ZINC13613191 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302284 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccccc3)C2)cc1 InChI=1S/C26H34FN3O/c27-23-14-12-20(13-15-23)17-21-7-6-16-30(18-21)19-22-8-4-5-11-25(22)29-26(31)28-24-9-2-1-3-10-24/h1-3,9-10,12-15,21-22,25H,4-8,11,16-19H2,(H2,28,29,31)/t21-,22-,25+/m0/s1 WWCDUCXBCODJGF-WRALFONMSA-N 50163667 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-phenyl-urea::CHEMBL362466 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163667&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11430170 104049650 CHEMBL362466 ZINC13613255 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302285 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302291 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)ccc1F InChI=1S/C28H35F2N3O2/c1-19(34)25-16-24(12-13-26(25)30)31-28(35)32-27-7-3-2-6-22(27)18-33-14-4-5-21(17-33)15-20-8-10-23(29)11-9-20/h8-13,16,21-22,27H,2-7,14-15,17-18H2,1H3,(H2,31,32,35)/t21-,22-,27+/m0/s1 XXFNYXARXWCONM-BCQCSXDESA-N 50163661 1-(3-Acetyl-4-fluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL365820 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163661&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11340670 104049644 CHEMBL365820 ZINC13613306 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302295 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3cccc(F)c3)C2)cc1 InChI=1S/C26H33F2N3O/c27-22-12-10-19(11-13-22)15-20-5-4-14-31(17-20)18-21-6-1-2-9-25(21)30-26(32)29-24-8-3-7-23(28)16-24/h3,7-8,10-13,16,20-21,25H,1-2,4-6,9,14-15,17-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 VQULRVZLPVJKAU-STWLZBDKSA-N 50163665 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-fluoro-phenyl)-urea::CHEMBL364263 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163665&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11385178 104049648 CHEMBL364263 ZINC13613268 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302296 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)NC3=CC4N=CCC4C=C3)C2)cc1 InChI=1S/C28H37FN4O/c29-24-10-7-20(8-11-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-26(23)32-28(34)31-25-12-9-22-13-14-30-27(22)17-25/h7-12,14,17,21-23,26-27H,1-6,13,15-16,18-19H2,(H2,31,32,34)/t21-,22?,23-,26+,27?/m0/s1 MEONWLWQWOSJIM-AZKOGFNYSA-N 50163666 1-(3a,7a-Dihydro-1H-indol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL373315 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163666&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936718 104049649 CHEMBL373315 ZINC28523475 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302299 Cc1csc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)n1 InChI=1S/C24H33FN4OS/c1-17-16-31-24(26-17)28-23(30)27-22-7-3-2-6-20(22)15-29-12-4-5-19(14-29)13-18-8-10-21(25)11-9-18/h8-11,16,19-20,22H,2-7,12-15H2,1H3,(H2,26,27,28,30)/t19-,20-,22+/m0/s1 YPYNMPIDPXJKTD-JAXLGGSGSA-N 50163670 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methyl-thiazol-2-yl)-urea::CHEMBL195044 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163670&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11442162 104049653 CHEMBL195044 ZINC13613343 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302303 Cc1ccccc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H36FN3O/c1-20-7-2-4-10-25(20)29-27(32)30-26-11-5-3-9-23(26)19-31-16-6-8-22(18-31)17-21-12-14-24(28)15-13-21/h2,4,7,10,12-15,22-23,26H,3,5-6,8-9,11,16-19H2,1H3,(H2,29,30,32)/t22-,23-,26+/m0/s1 AUZDFHZZRBZEPU-JCYRPKCISA-N 50163671 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-o-tolyl-urea::CHEMBL176077 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163671&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11154845 104049654 CHEMBL176077 ZINC13613257 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302310 CC(=O)c1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-6-4-7-26(18-23)30-28(34)31-27-8-3-2-5-24(27)19-32-15-13-22(14-16-32)17-21-9-11-25(29)12-10-21/h4,6-7,9-12,18,22,24,27H,2-3,5,8,13-17,19H2,1H3,(H2,30,31,34) KUOOPYAWZGYOPB-UHFFFAOYSA-N 50163640 1-(3-Acetyl-phenyl)-3-{2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL367992 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163640&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9804542 104049623 CHEMBL367992 ZINC13613195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302312 Cc1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)no1 InChI=1S/C24H33FN4O2/c1-17-13-23(28-31-17)27-24(30)26-22-7-3-2-6-20(22)16-29-12-4-5-19(15-29)14-18-8-10-21(25)11-9-18/h8-11,13,19-20,22H,2-7,12,14-16H2,1H3,(H2,26,27,28,30)/t19-,20-,22+/m0/s1 DWZGXOWWEDECCU-JAXLGGSGSA-N 50163674 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(5-methyl-isoxazol-3-yl)-urea::CHEMBL193526 C-C chemokine receptor type 3 Homo sapiens 2.7 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163674&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11487192 104049657 CHEMBL193526 ZINC13613352 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302314 CNC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(C)=O)c1CN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C30H33FN4O3/c1-20(36)23-5-3-6-25(18-23)33-30(38)34-28-8-4-7-26(29(37)32-2)27(28)19-35-15-13-22(14-16-35)17-21-9-11-24(31)12-10-21/h3-12,18,22H,13-17,19H2,1-2H3,(H,32,37)(H2,33,34,38) AYLIGBDQTHFVLJ-UHFFFAOYSA-N 50117461 3-[3-(3-Acetyl-phenyl)-ureido]-2-[4-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-N-methyl-benzamide::CHEMBL123611 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117461&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9892753 104011017 CHEMBL123611 ZINC03974016 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302317 O=C(N[C@@H]1CCCC[C@H]1CN1CCC(Cc2ccccc2)CC1)Nc1cccc(c1)C#N InChI=1S/C27H34N4O/c28-19-23-9-6-11-25(18-23)29-27(32)30-26-12-5-4-10-24(26)20-31-15-13-22(14-16-31)17-21-7-2-1-3-8-21/h1-3,6-9,11,18,22,24,26H,4-5,10,12-17,20H2,(H2,29,30,32)/t24-,26+/m0/s1 SMTRGPNBXDCVFA-AZGAKELHSA-N 50163664 1-[(1R,2S)-2-(4-Benzyl-piperidin-1-ylmethyl)-cyclohexyl]-3-(3-cyano-phenyl)-urea::CHEMBL175679 C-C chemokine receptor type 3 Homo sapiens 9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163664&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44387850 104049647 CHEMBL175679 ZINC28113861 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302323 COc1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccccc3)CC2)c1 InChI=1S/C27H37N3O2/c1-32-25-12-7-11-24(19-25)28-27(31)29-26-13-6-5-10-23(26)20-30-16-14-22(15-17-30)18-21-8-3-2-4-9-21/h2-4,7-9,11-12,19,22-23,26H,5-6,10,13-18,20H2,1H3,(H2,28,29,31) FSIZZJSQRKUBMT-UHFFFAOYSA-N 50163672 1-[2-(4-Benzyl-piperidin-1-ylmethyl)-cyclohexyl]-3-(3-methoxy-phenyl)-urea::CHEMBL366654 C-C chemokine receptor type 3 Homo sapiens 423.0 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163672&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9845853 104049655 CHEMBL366654 ZINC28111808 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302329 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccccc3F)C2)cc1 InChI=1S/C26H33F2N3O/c27-22-13-11-19(12-14-22)16-20-6-5-15-31(17-20)18-21-7-1-3-9-24(21)29-26(32)30-25-10-4-2-8-23(25)28/h2,4,8,10-14,20-21,24H,1,3,5-7,9,15-18H2,(H2,29,30,32)/t20-,21-,24+/m0/s1 MXFQLVWOVUVANY-AWRGLXIESA-N 50163675 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(2-fluoro-phenyl)-urea::CHEMBL193330 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163675&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11351206 104049658 CHEMBL193330 ZINC13613265 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302330 COc1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC(Cc3ccc(F)cc3)CC2)c1 InChI=1S/C27H36FN3O2/c1-33-25-7-4-6-24(18-25)29-27(32)30-26-8-3-2-5-22(26)19-31-15-13-21(14-16-31)17-20-9-11-23(28)12-10-20/h4,6-7,9-12,18,21-22,26H,2-3,5,8,13-17,19H2,1H3,(H2,29,30,32)/t22-,26+/m0/s1 YLLQTYFPCPQMDK-BKMJKUGQSA-N 50163679 1-{(1R,2S)-2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(3-methoxy-phenyl)-urea::CHEMBL175559 C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163679&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11396851 104049662 CHEMBL175559 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302332 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3nncs3)C2)cc1 InChI=1S/C22H30FN5OS/c23-19-9-7-16(8-10-19)12-17-4-3-11-28(13-17)14-18-5-1-2-6-20(18)25-21(29)26-22-27-24-15-30-22/h7-10,15,17-18,20H,1-6,11-14H2,(H2,25,26,27,29)/t17-,18-,20+/m0/s1 NOJKOZWXECFWRZ-CMKODMSKSA-N 50163683 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[1,3,4]thiadiazol-2-yl-urea::CHEMBL364977 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163683&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11750808 104049666 CHEMBL364977 ZINC13613337 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302334 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)NC3C=CCC=N3)C2)cc1 InChI=1S/C25H35FN4O/c26-22-12-10-19(11-13-22)16-20-6-5-15-30(17-20)18-21-7-1-2-8-23(21)28-25(31)29-24-9-3-4-14-27-24/h3,9-14,20-21,23-24H,1-2,4-8,15-18H2,(H2,28,29,31)/t20-,21-,23+,24?/m0/s1 DMLPMBSMNWXAAQ-NCYQSSKLSA-N 50163682 1-(1,2-Dihydro-pyridin-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL192240 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163682&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936720 104049665 CHEMBL192240 ZINC28520383 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302340 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3nccs3)C2)cc1 InChI=1S/C23H31FN4OS/c24-20-9-7-17(8-10-20)14-18-4-3-12-28(15-18)16-19-5-1-2-6-21(19)26-22(29)27-23-25-11-13-30-23/h7-11,13,18-19,21H,1-6,12,14-16H2,(H2,25,26,27,29)/t18-,19-,21+/m0/s1 ZKBWZHHPBACPCQ-IRFCIJBXSA-N 50163676 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-thiazol-2-yl-urea::CHEMBL195129 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163676&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11419003 104049659 CHEMBL195129 ZINC13613340 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302344 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)NC3=Cc4[nH]cnc4CC3)C2)cc1 InChI=1S/C27H36FN5O/c28-22-9-7-19(8-10-22)14-20-4-3-13-33(16-20)17-21-5-1-2-6-24(21)32-27(34)31-23-11-12-25-26(15-23)30-18-29-25/h7-10,15,18,20-21,24H,1-6,11-14,16-17H2,(H,29,30)(H2,31,32,34)/t20-,21-,24+/m0/s1 SXVBBECFZIPRKV-AWRGLXIESA-N 50163677 1-(3a,4-Dihydro-1H-benzoimidazol-5-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195191 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163677&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936719 104049660 CHEMBL195191 ZINC28523811 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302345 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3nc4c(Cl)cccc4s3)C2)cc1 InChI=1S/C27H32ClFN4OS/c28-22-7-3-9-24-25(22)31-27(35-24)32-26(34)30-23-8-2-1-6-20(23)17-33-14-4-5-19(16-33)15-18-10-12-21(29)13-11-18/h3,7,9-13,19-20,23H,1-2,4-6,8,14-17H2,(H2,30,31,32,34)/t19-,20-,23+/m0/s1 CCWUVBRDCQPCJX-SXWKCWPCSA-N 50163660 1-(4-Chloro-benzothiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195790 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163660&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11214474 104049643 CHEMBL195790 ZINC03976345 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302361 Cc1ccc(F)cc1NC(=O)N[C@@H]1CCCC[C@H]1CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H35F2N3O/c1-19-8-11-24(29)16-26(19)31-27(33)30-25-7-3-2-6-22(25)18-32-14-4-5-21(17-32)15-20-9-12-23(28)13-10-20/h8-13,16,21-22,25H,2-7,14-15,17-18H2,1H3,(H2,30,31,33)/t21-,22-,25+/m0/s1 LRWILVHFHINPBK-WRALFONMSA-N 50163680 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(5-fluoro-2-methyl-phenyl)-urea::CHEMBL364673 C-C chemokine receptor type 3 Homo sapiens 4.6 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163680&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11259591 104049663 CHEMBL364673 ZINC13613277 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302362 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(cc3)-n3cncn3)C2)cc1 InChI=1S/C28H35FN6O/c29-24-9-7-21(8-10-24)16-22-4-3-15-34(17-22)18-23-5-1-2-6-27(23)33-28(36)32-25-11-13-26(14-12-25)35-20-30-19-31-35/h7-14,19-20,22-23,27H,1-6,15-18H2,(H2,32,33,36)/t22-,23-,27+/m0/s1 QAZWZNQUFOFJJZ-VMODYCNZSA-N 50163681 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-[1,2,4]triazol-1-yl-phenyl)-urea::CHEMBL364068 C-C chemokine receptor type 3 Homo sapiens 2.2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163681&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11179351 104049664 CHEMBL364068 ZINC13613357 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302363 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc(F)c(F)c3)C2)cc1 InChI=1S/C26H32F3N3O/c27-21-9-7-18(8-10-21)14-19-4-3-13-32(16-19)17-20-5-1-2-6-25(20)31-26(33)30-22-11-12-23(28)24(29)15-22/h7-12,15,19-20,25H,1-6,13-14,16-17H2,(H2,30,31,33)/t19-,20-,25+/m0/s1 RKLGZRTYSTXJRW-ZYLNGJIFSA-N 50163684 1-(3,4-Difluoro-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL194384 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163684&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11396995 104049667 CHEMBL194384 ZINC13613270 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302365 CC(=O)c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C30H38FN3O3/c1-20(35)25-15-26(21(2)36)17-28(16-25)32-30(37)33-29-8-4-3-7-24(29)19-34-13-5-6-23(18-34)14-22-9-11-27(31)12-10-22/h9-12,15-17,23-24,29H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,37)/t23-,24-,29+/m0/s1 XNECWHFEDUTGHE-NDIVSWGXSA-N 50163650 1-(3,5-Diacetyl-phenyl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL193575 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163650&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11409583 104049633 CHEMBL193575 ZINC13613303 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302371 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4CNNc4c3)C2)cc1 InChI=1S/C27H36FN5O/c28-23-10-7-19(8-11-23)14-20-4-3-13-33(17-20)18-22-5-1-2-6-25(22)31-27(34)30-24-12-9-21-16-29-32-26(21)15-24/h7-12,15,20,22,25,29,32H,1-6,13-14,16-18H2,(H2,30,31,34)/t20-,22-,25+/m0/s1 IWLSFGNCEVXJQV-UWDQQESISA-N 50163662 1-(3a,7a-Dihydro-1H-indazol-6-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL191604 C-C chemokine receptor type 3 Homo sapiens 0.060000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163662&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 91936717 104049645 CHEMBL191604 ZINC28520637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302376 Fc1ccc(CC2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ccc4c3)C2)cc1 InChI=1S/C28H35FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-14,17,21,23,27,30H,1-6,15-16,18-19H2,(H2,31,32,34)/t21?,23-,27+/m0/s1 YHFFIZVSOADVRF-NPNLJVTBSA-N 50163641 1-{(1R,2S)-2-[3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(1H-indol-5-yl)-urea::CHEMBL195348 C-C chemokine receptor type 3 Homo sapiens 2.1 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163641&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44401328 104049624 CHEMBL195348 ZINC28523574 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50302377 Cn1nnnc1-c1cc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C30H38FN11O/c1-40-28(34-36-38-40)23-15-24(29-35-37-39-41(29)2)17-26(16-23)32-30(43)33-27-8-4-3-7-22(27)19-42-13-5-6-21(18-42)14-20-9-11-25(31)12-10-20/h9-12,15-17,21-22,27H,3-8,13-14,18-19H2,1-2H3,(H2,32,33,43)/t21-,22-,27+/m0/s1 DRZLAUYXLXUZDX-BCQCSXDESA-N 50163678 1-[3,5-Bis-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL382108 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163678&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11169258 104049661 CHEMBL382108 ZINC03976347 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297163 Nc1cccc(c1)C(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H29Cl2N3O/c25-22-5-4-18(15-23(22)26)14-17-6-10-28(11-7-17)21-8-12-29(13-9-21)24(30)19-2-1-3-20(27)16-19/h1-5,15-17,21H,6-14,27H2 VTSQOKIAZAEEBJ-UHFFFAOYSA-N 50161408 (3-Amino-phenyl)-[4-(3,4-dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-methanone::CHEMBL180599 C-C chemokine receptor type 3 Homo sapiens 122 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161408&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389699 104047714 CHEMBL180599 ZINC28135162 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297165 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cnnc3ccccc23)cc1Cl InChI=1S/C26H28Cl2N4O/c27-23-6-5-19(16-24(23)28)15-18-7-11-31(12-8-18)20-9-13-32(14-10-20)26(33)22-17-29-30-25-4-2-1-3-21(22)25/h1-6,16-18,20H,7-15H2 INRDXFLYZZTPAF-UHFFFAOYSA-N 50161409 CHEMBL362017::Cinnolin-4-yl-[4-(3,4-dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-methanone C-C chemokine receptor type 3 Homo sapiens 46 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161409&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389725 104047715 CHEMBL362017 ZINC28331226 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297166 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(Cl)ccc2Cl)CC1 InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-21(19)18-26(31)30-14-10-24(11-15-30)29-12-8-20(9-13-29)16-22-17-23(27)6-7-25(22)28/h2-7,17,20,24H,8-16,18H2,1H3 XXFFTNXHIBHWRD-UHFFFAOYSA-N 50161410 1-[4-(2,5-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181290 C-C chemokine receptor type 3 Homo sapiens 251 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161410&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389698 104047716 CHEMBL181290 ZINC28134411 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297167 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(Cl)cc(Cl)c2)CC1 InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-22(19)17-26(31)30-12-8-25(9-13-30)29-10-6-20(7-11-29)14-21-15-23(27)18-24(28)16-21/h2-5,15-16,18,20,25H,6-14,17H2,1H3 DFMBOSJDTBSFPP-UHFFFAOYSA-N 50161411 1-[4-(3,5-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181232 C-C chemokine receptor type 3 Homo sapiens 938.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161411&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389729 104047717 CHEMBL181232 ZINC28331312 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297168 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cccc(Cl)c2)CC1 InChI=1S/C26H33ClN2O/c1-20-5-2-3-7-23(20)19-26(30)29-15-11-25(12-16-29)28-13-9-21(10-14-28)17-22-6-4-8-24(27)18-22/h2-8,18,21,25H,9-17,19H2,1H3 QENRRRMNQOTYRO-UHFFFAOYSA-N 50161412 1-[4-(3-Chloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL440750 C-C chemokine receptor type 3 Homo sapiens 128 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161412&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389747 104047718 CHEMBL440750 ZINC28130581 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297169 CS(=O)(=O)NC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H34Cl2N4O3S/c1-39(37,38)33-18-24-19-35(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-34(14-10-25)29(36)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25,33H,8-10,12-15,18-19H2,1H3/t21-,24-/m1/s1 BJPMPSOWBXBZCM-ZJSXRUAMSA-N 50161414 CHEMBL181789::N-[(3S,4S)-4-(3,4-Dichloro-benzyl)-1''-(quinoline-6-carbonyl)-[1,4'']bipiperidinyl-3-ylmethyl]-methanesulfonamide C-C chemokine receptor type 3 Homo sapiens 331.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161414&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389868 104047720 CHEMBL181789 ZINC28134067 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297170 Nc1ccc(cc1)C(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H29Cl2N3O/c25-22-6-1-18(16-23(22)26)15-17-7-11-28(12-8-17)21-9-13-29(14-10-21)24(30)19-2-4-20(27)5-3-19/h1-6,16-17,21H,7-15,27H2 WFUNGSLTFAAGKM-UHFFFAOYSA-N 50161413 (4-Amino-phenyl)-[4-(3,4-dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-methanone::CHEMBL180122 C-C chemokine receptor type 3 Homo sapiens 136 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161413&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389709 104047719 CHEMBL180122 ZINC28121422 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297171 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)cc2F)CC1 InChI=1S/C26H32ClFN2O/c1-19-4-2-3-5-21(19)17-26(31)30-14-10-24(11-15-30)29-12-8-20(9-13-29)16-22-6-7-23(27)18-25(22)28/h2-7,18,20,24H,8-17H2,1H3 ZIHKJSNQUZDFRX-UHFFFAOYSA-N 50161417 1-[4-(4-Chloro-2-fluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL178916 C-C chemokine receptor type 3 Homo sapiens 145 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161417&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389712 104047723 CHEMBL178916 ZINC28123560 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297172 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C26H33FN2O/c1-20-4-2-3-5-23(20)19-26(30)29-16-12-25(13-17-29)28-14-10-22(11-15-28)18-21-6-8-24(27)9-7-21/h2-9,22,25H,10-19H2,1H3 KHXJXFWUMHULPM-UHFFFAOYSA-N 50161416 1-[4-(4-Fluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL178771 C-C chemokine receptor type 3 Homo sapiens 111 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161416&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389719 104047722 CHEMBL178771 ZINC28126937 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297174 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccnc2ccccc12 InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(13-9-20(27)16-19-6-7-24(29)25(30)17-19)21-10-14-32(15-11-21)28(34)23-8-12-31-26-5-3-2-4-22(23)26/h2-8,12,17,20-21,27H,9-11,13-16,18H2,1H3/t20-,27-/m1/s1 HHQHIMRAAROGLI-NFQMXDRXSA-N 50161418 CHEMBL180621::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinolin-4-yl-methanone C-C chemokine receptor type 3 Homo sapiens 26 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161418&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389832 104047724 CHEMBL180621 ZINC28331284 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297175 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(12-8-21(27)15-19-4-6-24(29)25(30)16-19)23-9-13-32(14-10-23)28(34)22-5-7-26-20(17-22)3-2-11-31-26/h2-7,11,16-17,21,23,27H,8-10,12-15,18H2,1H3/t21-,27-/m1/s1 OTRJGARPBIJRKG-JIPXPUAJSA-N 50161419 CHEMBL178818::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 7.70 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161419&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11477767 104047725 CHEMBL178818 ZINC28123566 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297176 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc3ncccc3c2)cc1Cl InChI=1S/C27H29Cl2N3O/c28-24-5-3-20(17-25(24)29)16-19-7-12-31(13-8-19)23-9-14-32(15-10-23)27(33)22-4-6-26-21(18-22)2-1-11-30-26/h1-6,11,17-19,23H,7-10,12-16H2 JIVMLAUZOHRZPP-UHFFFAOYSA-N 50161421 CHEMBL362649::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161421&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389737 104047727 CHEMBL362649 ZINC28131010 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297178 CCO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H33Cl2N3O2/c1-2-36-28-19-34(13-9-22(28)16-20-5-7-25(30)26(31)17-20)24-10-14-33(15-11-24)29(35)23-6-8-27-21(18-23)4-3-12-32-27/h3-8,12,17-18,22,24,28H,2,9-11,13-16,19H2,1H3/t22-,28-/m1/s1 BCTREWRHSJQVCU-SKCUWOTOSA-N 50161422 CHEMBL181379::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-ethoxy-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 33 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161422&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389738 104047728 CHEMBL181379 ZINC28131138 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297179 CC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H33Cl2N3O/c1-2-21-19-34(13-9-22(21)16-20-5-7-26(30)27(31)17-20)25-10-14-33(15-11-25)29(35)24-6-8-28-23(18-24)4-3-12-32-28/h3-8,12,17-18,21-22,25H,2,9-11,13-16,19H2,1H3/t21-,22-/m1/s1 ARYIMOASXQFMAS-FGZHOGPDSA-N 50161423 CHEMBL178136::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-ethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161423&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389704 104047729 CHEMBL178136 ZINC28127548 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297180 FC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H30Cl2FN3O/c29-25-5-3-19(15-26(25)30)14-20-7-11-34(18-23(20)17-31)24-8-12-33(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-32-27/h1-6,10,15-16,20,23-24H,7-9,11-14,17-18H2/t20-,23-/m1/s1 FVAOVJNENUJPIS-NFBKMPQASA-N 50161425 CHEMBL178422::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-fluoromethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 46 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161425&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389736 104047731 CHEMBL178422 ZINC28130379 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297181 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)cc2Cl)CC1 InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-21(19)17-26(31)30-14-10-24(11-15-30)29-12-8-20(9-13-29)16-22-6-7-23(27)18-25(22)28/h2-7,18,20,24H,8-17H2,1H3 HYKZDHSSNYWLPQ-UHFFFAOYSA-N 50161426 1-[4-(2,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL369287 C-C chemokine receptor type 3 Homo sapiens 56 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161426&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389683 104047732 CHEMBL369287 ZINC28131474 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297182 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2cnccc2n1 InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-7-19(26)14-18-2-4-22(28)23(29)15-18)21-8-12-32(13-9-21)27(34)25-5-3-20-16-30-10-6-24(20)31-25/h2-6,10,15-16,19,21,26H,7-9,11-14,17H2,1H3/t19-,26-/m1/s1 LBHFPBVNSINXHG-NIYFSFCBSA-N 50161429 CHEMBL179490::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-[1,6]naphthyridin-2-yl-methanone C-C chemokine receptor type 3 Homo sapiens 35 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161429&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389910 104047735 CHEMBL179490 ZINC28120134 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297183 CC(=O)NC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C30H34Cl2N4O2/c1-20(37)34-18-25-19-36(12-8-22(25)15-21-4-6-27(31)28(32)16-21)26-9-13-35(14-10-26)30(38)24-5-7-29-23(17-24)3-2-11-33-29/h2-7,11,16-17,22,25-26H,8-10,12-15,18-19H2,1H3,(H,34,37)/t22-,25-/m1/s1 YXKQDJSENLLDCP-RCZVLFRGSA-N 50161428 CHEMBL362401::N-[(3R,4S)-4-(3,4-Dichloro-benzyl)-1''-(quinoline-6-carbonyl)-[1,4'']bipiperidinyl-3-ylmethyl]-acetamide C-C chemokine receptor type 3 Homo sapiens 205 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161428&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389770 104047734 CHEMBL362401 ZINC28135801 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297184 COc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)Cc2ccccc2C)cc1 InChI=1S/C27H36N2O2/c1-21-5-3-4-6-24(21)20-27(30)29-17-13-25(14-18-29)28-15-11-23(12-16-28)19-22-7-9-26(31-2)10-8-22/h3-10,23,25H,11-20H2,1-2H3 OZIPSESMEGJVGY-UHFFFAOYSA-N 50161427 1-[4-(4-Methoxy-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181230 C-C chemokine receptor type 3 Homo sapiens 792 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161427&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389732 104047733 CHEMBL181230 ZINC28331357 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297185 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Br)cc2)CC1 InChI=1S/C26H33BrN2O/c1-20-4-2-3-5-23(20)19-26(30)29-16-12-25(13-17-29)28-14-10-22(11-15-28)18-21-6-8-24(27)9-7-21/h2-9,22,25H,10-19H2,1H3 GYVMZRRXTBAOSI-UHFFFAOYSA-N 50161431 1-[4-(4-Bromo-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-(2-tert-butyl-phenyl)-ethanone::CHEMBL178576 C-C chemokine receptor type 3 Homo sapiens 66 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161431&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389684 104047737 CHEMBL178576 ZINC28130754 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297186 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(F)c2)CC1 InChI=1S/C26H32ClFN2O/c1-19-4-2-3-5-22(19)18-26(31)30-14-10-23(11-15-30)29-12-8-20(9-13-29)16-21-6-7-24(27)25(28)17-21/h2-7,17,20,23H,8-16,18H2,1H3 AOPIAXYQYXZZMC-UHFFFAOYSA-N 50161435 1-[4-(4-Chloro-3-fluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181678 C-C chemokine receptor type 3 Homo sapiens 191 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161435&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389730 104047741 CHEMBL181678 ZINC28331346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297189 C[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C28H31Cl2N3O/c1-19-18-33(12-8-21(19)15-20-4-6-25(29)26(30)16-20)24-9-13-32(14-10-24)28(34)23-5-7-27-22(17-23)3-2-11-31-27/h2-7,11,16-17,19,21,24H,8-10,12-15,18H2,1H3/t19-,21-/m1/s1 GIMAFLOOKFRGCY-TZIWHRDSSA-N 50161415 CHEMBL181460::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 14.0 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161415&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389688 104047721 CHEMBL181460 ZINC28134725 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297190 Clc1ccc(C[C@H]2CCN(C[C@H]2C=C)C2CCN(CC2)C(=O)c2ccc3ncccc3c2)cc1Cl InChI=1S/C29H31Cl2N3O/c1-2-21-19-34(13-9-22(21)16-20-5-7-26(30)27(31)17-20)25-10-14-33(15-11-25)29(35)24-6-8-28-23(18-24)4-3-12-32-28/h2-8,12,17-18,21-22,25H,1,9-11,13-16,19H2/t21-,22-/m1/s1 HDRXESCDVUCCBX-FGZHOGPDSA-N 50161430 CHEMBL178887::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-vinyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161430&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11386642 104047736 CHEMBL178887 ZINC28126923 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297191 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2nccnc2c1 InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-6-19(26)14-18-2-4-22(28)23(29)15-18)21-7-12-32(13-8-21)27(34)20-3-5-24-25(16-20)31-10-9-30-24/h2-5,9-10,15-16,19,21,26H,6-8,11-14,17H2,1H3/t19-,26-/m1/s1 IMCGOKASJNONCI-NIYFSFCBSA-N 50161433 CHEMBL441848::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinoxalin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 48 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161433&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389765 104047739 CHEMBL441848 ZINC28134778 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297192 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3cccnc23)cc1Cl InChI=1S/C27H29Cl2N3O/c28-24-7-6-20(18-25(24)29)17-19-8-13-31(14-9-19)22-10-15-32(16-11-22)27(33)23-5-1-3-21-4-2-12-30-26(21)23/h1-7,12,18-19,22H,8-11,13-17H2 XZFBUJIMEMZOAG-UHFFFAOYSA-N 50161438 CHEMBL178875::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-quinolin-8-yl-methanone C-C chemokine receptor type 3 Homo sapiens 68 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161438&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389677 104047744 CHEMBL178875 ZINC28132130 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297193 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cccc(Cl)c2Cl)CC1 InChI=1S/C26H32Cl2N2O/c1-19-5-2-3-6-21(19)18-25(31)30-15-11-23(12-16-30)29-13-9-20(10-14-29)17-22-7-4-8-24(27)26(22)28/h2-8,20,23H,9-18H2,1H3 IYJSUGZACNXSGX-UHFFFAOYSA-N 50161434 1-[4-(2,3-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL178286 C-C chemokine receptor type 3 Homo sapiens 103 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161434&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389669 104047740 CHEMBL178286 ZINC28132023 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297194 CC(=O)N[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H32Cl2N4O2/c1-19(36)33-28-18-35(12-8-22(28)15-20-4-6-25(30)26(31)16-20)24-9-13-34(14-10-24)29(37)23-5-7-27-21(17-23)3-2-11-32-27/h2-7,11,16-17,22,24,28H,8-10,12-15,18H2,1H3,(H,33,36)/t22-,28-/m1/s1 RGNTWXUHBNURAO-SKCUWOTOSA-N 50161437 CHEMBL180989::N-[(3S,4S)-4-(3,4-Dichloro-benzyl)-1''-(quinoline-6-carbonyl)-[1,4'']bipiperidinyl-3-yl]-acetamide C-C chemokine receptor type 3 Homo sapiens 164 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161437&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389722 104047743 CHEMBL180989 ZINC28330473 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297195 COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1 InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1 NIBJOLRGYNXOPG-QPPBQGQZSA-N 50161436 CHEMBL178438::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxymethyl-[1,4'']bipiperidinyl-1''-yl]-quinolin-6-yl-methanone C-C chemokine receptor type 3 Homo sapiens 394 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161436&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389675 104047742 CHEMBL178438 ZINC28132125 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297197 CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2cccnc2n1 InChI=1S/C27H30Cl2N4O2/c1-35-25-17-33(12-8-20(25)15-18-4-6-22(28)23(29)16-18)21-9-13-32(14-10-21)27(34)24-7-5-19-3-2-11-30-26(19)31-24/h2-7,11,16,20-21,25H,8-10,12-15,17H2,1H3/t20-,25-/m1/s1 AXAAKILJQSGHDI-CJFMBICVSA-N 50161432 CHEMBL181273::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-[1,8]naphthyridin-2-yl-methanone C-C chemokine receptor type 3 Homo sapiens 15 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161432&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11283679 104047738 CHEMBL181273 ZINC28135086 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297198 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cnc3ccccc3c2)cc1Cl InChI=1S/C27H29Cl2N3O/c28-24-6-5-20(16-25(24)29)15-19-7-11-31(12-8-19)23-9-13-32(14-10-23)27(33)22-17-21-3-1-2-4-26(21)30-18-22/h1-6,16-19,23H,7-15H2 WPWOBIYXOOJNTH-UHFFFAOYSA-N 50161440 CHEMBL359850::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-quinolin-3-yl-methanone C-C chemokine receptor type 3 Homo sapiens 458 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161440&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389735 104047746 CHEMBL359850 ZINC28130365 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297199 Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccnc3ccccc23)cc1Cl InChI=1S/C27H29Cl2N3O/c28-24-6-5-20(18-25(24)29)17-19-8-13-31(14-9-19)21-10-15-32(16-11-21)27(33)23-7-12-30-26-4-2-1-3-22(23)26/h1-7,12,18-19,21H,8-11,13-17H2 JHWMHYPVQFVHIT-UHFFFAOYSA-N 50161443 CHEMBL180813::[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-quinolin-4-yl-methanone C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161443&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389752 104047749 CHEMBL180813 ZINC28130042 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50297200 Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2cc(F)cc(Cl)c2)CC1 InChI=1S/C26H32ClFN2O/c1-19-4-2-3-5-22(19)17-26(31)30-12-8-25(9-13-30)29-10-6-20(7-11-29)14-21-15-23(27)18-24(28)16-21/h2-5,15-16,18,20,25H,6-14,17H2,1H3 CJVAFNHVSYHRHI-UHFFFAOYSA-N 50161444 1-[4-(3-Chloro-5-fluoro-benzyl)-[1,4'']bipiperidinyl-1''-yl]-2-o-tolyl-ethanone::CHEMBL181794 C-C chemokine receptor type 3 Homo sapiens 504 ChEMBL 10.1016/j.bmcl.2005.01.016 10.7270/Q2B857NS 15713390 Ting, PC; Lee, JF; Wu, J; Umland, SP; Aslanian, R; Cao, J; Dong, Y; Garlisi, CG; Gilbert, EJ; Huang, Y; Jakway, J; Kelly, J; Liu, Z; McCombie, S; Shah, H; Tian, F; Wan, Y; Shih, NY Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44389751 104047750 CHEMBL181794 ZINC28131380 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50346460 FC(F)(F)c1cc(CNC(=O)[C@@H](NCCN2CCCCC2)c2ccsc2)cc(c1)C(F)(F)F InChI=1S/C22H25F6N3OS/c23-21(24,25)17-10-15(11-18(12-17)22(26,27)28)13-30-20(32)19(16-4-9-33-14-16)29-5-8-31-6-2-1-3-7-31/h4,9-12,14,19,29H,1-3,5-8,13H2,(H,30,32)/t19-/m0/s1 NLWNSKCTNYPJQF-IBGZPJMESA-N 50187033 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piperidin-1-yl)ethylamino)-2-(thiophen-3-yl)acetamide::CHEMBL211775 C-C chemokine receptor type 3 Homo sapiens >1000 ChEMBL 10.1016/j.bmcl.2006.04.045 10.7270/Q2N01645 16698264 Yang, L; Zhou, C; Guo, L; Morriello, G; Butora, G; Pasternak, A; Parsons, WH; Mills, SG; MacCoss, M; Vicario, PP; Zweerink, H; Ayala, JM; Goyal, S; Hanlon, WA; Cascieri, MA; Springer, MS Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187033&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10323427 104071072 CHEMBL211775 ZINC34804147 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357629 O=C(NCCCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C24H30N4O/c25-18-21-9-6-11-23(17-21)28-24(29)27-13-5-4-10-22-16-20(12-14-26-22)15-19-7-2-1-3-8-19/h1-3,6-9,11,17,20,22,26H,4-5,10,12-16H2,(H2,27,28,29)/t20-,22-/m0/s1 UGXVZPDCLIQAPG-UNMCSNQZSA-N 50193761 (+/-)1-(4-((2S,4R)-4-benzylpiperidin-2-yl)butyl)-3-(3-cyanophenyl)urea::CHEMBL220800 C-C chemokine receptor type 3 Homo sapiens 142 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193761&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419323 104076157 CHEMBL220800 ZINC36352011 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357632 CC(=O)c1cccc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2)c1 InChI=1S/C24H30FN3O2/c1-17(29)20-4-2-5-23(16-20)28-24(30)27-12-3-6-22-15-19(11-13-26-22)14-18-7-9-21(25)10-8-18/h2,4-5,7-10,16,19,22,26H,3,6,11-15H2,1H3,(H2,27,28,30)/t19-,22-/m0/s1 WYKUNXLKNJTHND-UGKGYDQZSA-N 50193763 (+)1-(3-((2S,4R)-4-(4-fluorobenzyl)piperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL219048 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193763&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419328 104076159 CHEMBL219048 ZINC34024255 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357636 O=C(NCCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-17-20-8-4-9-22(16-20)27-23(28)26-12-5-10-21-15-19(11-13-25-21)14-18-6-2-1-3-7-18/h1-4,6-9,16,19,21,25H,5,10-15H2,(H2,26,27,28)/t19-,21-/m0/s1 FFTNCZSASXDDKK-FPOVZHCZSA-N 50193762 (+)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::CHEMBL218997 C-C chemokine receptor type 3 Homo sapiens 13.0 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193762&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419314 104076158 CHEMBL218997 ZINC36093275 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357639 CC(=O)CN1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C29H36FN3O4/c1-19(34)18-33-12-10-23(13-22-6-8-26(30)9-7-22)14-28(33)5-4-11-31-29(37)32-27-16-24(20(2)35)15-25(17-27)21(3)36/h6-9,15-17,23,28H,4-5,10-14,18H2,1-3H3,(H2,31,32,37)/t23-,28-/m0/s1 FTVCCHUPUJEUIW-FIPFOOKPSA-N 50193770 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-oxopropyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL376737 C-C chemokine receptor type 3 Homo sapiens 0.9 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193770&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419298 104076166 CHEMBL376737 ZINC36093269 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357640 CC(=O)c1cccc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC=C)c1 InChI=1S/C27H34FN3O2/c1-3-15-31-16-13-22(17-21-9-11-24(28)12-10-21)18-26(31)8-5-14-29-27(33)30-25-7-4-6-23(19-25)20(2)32/h3-4,6-7,9-12,19,22,26H,1,5,8,13-18H2,2H3,(H2,29,30,33)/t22-,26-/m0/s1 AZOHUEDNMOIDOC-NVQXNPDNSA-N 50193771 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-allylpiperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL221903 C-C chemokine receptor type 3 Homo sapiens 4.1 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193771&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419340 104076167 CHEMBL221903 ZINC36093278 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357641 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CCF)cc(c1)C(C)=O InChI=1S/C28H35F2N3O3/c1-19(34)23-16-24(20(2)35)18-26(17-23)32-28(36)31-11-3-4-27-15-22(9-12-33(27)13-10-29)14-21-5-7-25(30)8-6-21/h5-8,16-18,22,27H,3-4,9-15H2,1-2H3,(H2,31,32,36)/t22-,27-/m0/s1 VCYYAUWOLSKMPO-CUNXSJBXSA-N 50193769 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-fluoroethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL220713 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193769&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419300 104076165 CHEMBL220713 ZINC36093271 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357647 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2)cc(c1)C(C)=O InChI=1S/C26H32FN3O3/c1-17(31)21-14-22(18(2)32)16-25(15-21)30-26(33)29-10-3-4-24-13-20(9-11-28-24)12-19-5-7-23(27)8-6-19/h5-8,14-16,20,24,28H,3-4,9-13H2,1-2H3,(H2,29,30,33)/t20-,24-/m0/s1 RKHFLVYZXJYWKW-RDPSFJRHSA-N 50193774 (+)1-(3-((2S,4R)-4-(4-fluorobenzyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL217987 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193774&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419331 104076170 CHEMBL217987 ZINC36093276 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357651 CC(=O)c1cccc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccccc3)CCN2)c1 InChI=1S/C24H31N3O2/c1-18(28)21-9-5-10-23(17-21)27-24(29)26-13-6-11-22-16-20(12-14-25-22)15-19-7-3-2-4-8-19/h2-5,7-10,17,20,22,25H,6,11-16H2,1H3,(H2,26,27,29)/t20-,22-/m0/s1 CVHOPXZORYBSMH-UNMCSNQZSA-N 50193768 (+/-)1-(3-acetylphenyl)-3-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)urea::CHEMBL218581 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193768&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419327 104076164 CHEMBL218581 ZINC33987516 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357653 CC(=O)c1cccc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC2CC2)c1 InChI=1S/C28H36FN3O2/c1-20(33)24-4-2-5-26(18-24)31-28(34)30-14-3-6-27-17-23(13-15-32(27)19-22-7-8-22)16-21-9-11-25(29)12-10-21/h2,4-5,9-12,18,22-23,27H,3,6-8,13-17,19H2,1H3,(H2,30,31,34)/t23-,27-/m0/s1 UCYBGEFJKJSJQI-HOFKKMOUSA-N 50193777 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(cyclopropylmethyl)piperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL220819 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193777&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419335 104076173 CHEMBL220819 ZINC36093277 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357657 O=C(NCCC[C@@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-17-20-8-4-9-22(16-20)27-23(28)26-12-5-10-21-15-19(11-13-25-21)14-18-6-2-1-3-7-18/h1-4,6-9,16,19,21,25H,5,10-15H2,(H2,26,27,28)/t19-,21+/m0/s1 FFTNCZSASXDDKK-PZJWPPBQSA-N 50193778 (+/-)1-(3-((2R,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::CHEMBL220866 C-C chemokine receptor type 3 Homo sapiens 386 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193778&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22966052 104076174 CHEMBL220866 ZINC03976511 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357658 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2C(N)=N)cc(c1)C(C)=O InChI=1S/C27H34FN5O3/c1-17(34)21-14-22(18(2)35)16-24(15-21)32-27(36)31-10-3-4-25-13-20(9-11-33(25)26(29)30)12-19-5-7-23(28)8-6-19/h5-8,14-16,20,25H,3-4,9-13H2,1-2H3,(H3,29,30)(H2,31,32,36)/t20-,25-/m0/s1 FVWTYUWMRRCCPG-CPJSRVTESA-N 50193764 (2S,4R)-2-{3-[3-(3,5-diacetyl-phenyl)-ureido]-propyl}-4-(4-fluoro-benzyl)-piperidine-1-carboxamidine::CHEMBL220766 C-C chemokine receptor type 3 Homo sapiens 4.3 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193764&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 20636465 104076160 CHEMBL220766 ZINC36093274 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357665 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CCO)cc(c1)C(C)=O InChI=1S/C28H36FN3O4/c1-19(34)23-16-24(20(2)35)18-26(17-23)31-28(36)30-10-3-4-27-15-22(9-11-32(27)12-13-33)14-21-5-7-25(29)8-6-21/h5-8,16-18,22,27,33H,3-4,9-15H2,1-2H3,(H2,30,31,36)/t22-,27-/m0/s1 KHIUUVSTTUGPRZ-CUNXSJBXSA-N 50193760 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-hydroxyethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL218568 C-C chemokine receptor type 3 Homo sapiens 0.9 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193760&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419295 104076156 CHEMBL218568 ZINC36093268 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357673 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC(N)=O)cc(c1)C(C)=O InChI=1S/C28H35FN4O4/c1-18(34)22-14-23(19(2)35)16-25(15-22)32-28(37)31-10-3-4-26-13-21(9-11-33(26)17-27(30)36)12-20-5-7-24(29)8-6-20/h5-8,14-16,21,26H,3-4,9-13,17H2,1-2H3,(H2,30,36)(H2,31,32,37)/t21-,26-/m0/s1 BRTWZDQCGNRNRK-LVXARBLLSA-N 50193772 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL385607 C-C chemokine receptor type 3 Homo sapiens 3.6 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193772&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419299 104076168 CHEMBL385607 ZINC36093270 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357675 O=C(NCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C22H26N4O/c23-16-19-7-4-8-21(15-19)26-22(27)25-12-10-20-14-18(9-11-24-20)13-17-5-2-1-3-6-17/h1-8,15,18,20,24H,9-14H2,(H2,25,26,27)/t18-,20-/m0/s1 VHBTZHUAFYABOU-ICSRJNTNSA-N 50193780 (+/-)1-(2-((2R,4R)-4-benzylpiperidin-2-yl)ethyl)-3-(3-cyanophenyl)urea::CHEMBL221901 C-C chemokine receptor type 3 Homo sapiens 185 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193780&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419322 104076176 CHEMBL221901 ZINC36352010 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357676 O=C(NCCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-17-20-8-4-9-22(16-20)27-23(28)26-12-5-10-21-15-19(11-13-25-21)14-18-6-2-1-3-7-18/h1-4,6-9,16,19,21,25H,5,10-15H2,(H2,26,27,28)/t19-,21-/m0/s1 FFTNCZSASXDDKK-FPOVZHCZSA-N 50193762 (+)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::CHEMBL218997 C-C chemokine receptor type 3 Homo sapiens 644 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193762&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419314 104076158 CHEMBL218997 ZINC36093275 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357679 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC=C)cc(c1)C(C)=O InChI=1S/C29H36FN3O3/c1-4-13-33-14-11-23(15-22-7-9-26(30)10-8-22)16-28(33)6-5-12-31-29(36)32-27-18-24(20(2)34)17-25(19-27)21(3)35/h4,7-10,17-19,23,28H,1,5-6,11-16H2,2-3H3,(H2,31,32,36)/t23-,28-/m0/s1 UHVITKONHRHSFJ-FIPFOOKPSA-N 50193759 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-allylpiperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL218262 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193759&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419345 104076155 CHEMBL218262 ZINC36093280 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357689 CC(=O)N1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C28H34FN3O4/c1-18(33)23-15-24(19(2)34)17-26(16-23)31-28(36)30-11-4-5-27-14-22(10-12-32(27)20(3)35)13-21-6-8-25(29)9-7-21/h6-9,15-17,22,27H,4-5,10-14H2,1-3H3,(H2,30,31,36)/t22-,27-/m0/s1 ZZJGNQRWIXQQDJ-CUNXSJBXSA-N 50193766 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-acetylpiperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL383879 C-C chemokine receptor type 3 Homo sapiens 3.9 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193766&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419306 104076162 CHEMBL383879 ZINC36093272 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357690 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC#C)cc(c1)C(C)=O InChI=1S/C29H34FN3O3/c1-4-13-33-14-11-23(15-22-7-9-26(30)10-8-22)16-28(33)6-5-12-31-29(36)32-27-18-24(20(2)34)17-25(19-27)21(3)35/h1,7-10,17-19,23,28H,5-6,11-16H2,2-3H3,(H2,31,32,36)/t23-,28-/m0/s1 MOOPIJCZPWGNKW-FIPFOOKPSA-N 50193758 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(prop-2-ynyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL220765 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193758&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419301 104076154 CHEMBL220765 ZINC28604020 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357691 CCCN1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C29H38FN3O3/c1-4-13-33-14-11-23(15-22-7-9-26(30)10-8-22)16-28(33)6-5-12-31-29(36)32-27-18-24(20(2)34)17-25(19-27)21(3)35/h7-10,17-19,23,28H,4-6,11-16H2,1-3H3,(H2,31,32,36)/t23-,28-/m0/s1 NNOWQHZNUGOGEV-FIPFOOKPSA-N 50193765 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-propylpiperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL386073 C-C chemokine receptor type 3 Homo sapiens 0.7 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193765&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419344 104076161 CHEMBL386073 ZINC03976516 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357696 CC(=O)c1cccc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CCO)c1 InChI=1S/C26H34FN3O3/c1-19(32)22-4-2-5-24(18-22)29-26(33)28-12-3-6-25-17-21(11-13-30(25)14-15-31)16-20-7-9-23(27)10-8-20/h2,4-5,7-10,18,21,25,31H,3,6,11-17H2,1H3,(H2,28,29,33)/t21-,25-/m0/s1 AEEJHYWVYVJIRH-OFVILXPXSA-N 50193781 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-hydroxyethyl)piperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL220801 C-C chemokine receptor type 3 Homo sapiens 7 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193781&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22966050 104076177 CHEMBL220801 ZINC36093279 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357699 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC(F)(F)F)cc(c1)C(C)=O InChI=1S/C28H33F4N3O3/c1-18(36)22-14-23(19(2)37)16-25(15-22)34-27(38)33-10-3-4-26-13-21(9-11-35(26)17-28(30,31)32)12-20-5-7-24(29)8-6-20/h5-8,14-16,21,26H,3-4,9-13,17H2,1-2H3,(H2,33,34,38)/t21-,26-/m0/s1 AKEDNWBVXPATHJ-LVXARBLLSA-N 50193782 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2,2,2-trifluoroethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL217928 C-C chemokine receptor type 3 Homo sapiens 1380 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193782&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419305 104076178 CHEMBL217928 ZINC28604028 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357703 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC(F)F)cc(c1)C(C)=O InChI=1S/C28H34F3N3O3/c1-18(35)22-14-23(19(2)36)16-25(15-22)33-28(37)32-10-3-4-26-13-21(9-11-34(26)17-27(30)31)12-20-5-7-24(29)8-6-20/h5-8,14-16,21,26-27H,3-4,9-13,17H2,1-2H3,(H2,32,33,37)/t21-,26-/m0/s1 VMQXOMTZSIHVEX-LVXARBLLSA-N 50193773 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2,2-difluoroethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL386493 C-C chemokine receptor type 3 Homo sapiens 12.4 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193773&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419303 104076169 CHEMBL386493 ZINC28604026 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357704 CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CCCO)cc(c1)C(C)=O InChI=1S/C29H38FN3O4/c1-20(35)24-17-25(21(2)36)19-27(18-24)32-29(37)31-11-3-5-28-16-23(10-13-33(28)12-4-14-34)15-22-6-8-26(30)9-7-22/h6-9,17-19,23,28,34H,3-5,10-16H2,1-2H3,(H2,31,32,37)/t23-,28-/m0/s1 ZSHFBVRJUAGORQ-FIPFOOKPSA-N 50193775 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(3-hydroxypropyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL384199 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193775&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419296 104076171 CHEMBL384199 ZINC03976519 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357705 CCC(=O)N1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C29H36FN3O4/c1-4-28(36)33-13-11-22(14-21-7-9-25(30)10-8-21)15-27(33)6-5-12-31-29(37)32-26-17-23(19(2)34)16-24(18-26)20(3)35/h7-10,16-18,22,27H,4-6,11-15H2,1-3H3,(H2,31,32,37)/t22-,27-/m0/s1 SOCOFADTVIPCCY-CUNXSJBXSA-N 50193776 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-propionylpiperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL384649 C-C chemokine receptor type 3 Homo sapiens 5.8 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193776&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419308 104076172 CHEMBL384649 ZINC36093273 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357706 CCCN1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H36FN3O2/c1-3-15-31-16-13-22(17-21-9-11-24(28)12-10-21)18-26(31)8-5-14-29-27(33)30-25-7-4-6-23(19-25)20(2)32/h4,6-7,9-12,19,22,26H,3,5,8,13-18H2,1-2H3,(H2,29,30,33)/t22-,26-/m0/s1 SHAKAEUQTANHLB-NVQXNPDNSA-N 50193767 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-propylpiperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL221067 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193767&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 12000105 104076163 CHEMBL221067 ZINC34013486 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357710 CN1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C25H32FN3O2/c1-18(30)21-5-3-6-23(17-21)28-25(31)27-13-4-7-24-16-20(12-14-29(24)2)15-19-8-10-22(26)11-9-19/h3,5-6,8-11,17,20,24H,4,7,12-16H2,1-2H3,(H2,27,28,31)/t20-,24-/m0/s1 SLSRYMJCMOWUIE-RDPSFJRHSA-N 50193779 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-methylpiperidin-2-yl)propyl)-3-(3-acetylphenyl)urea::CHEMBL218174 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193779&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 16126667 104076175 CHEMBL218174 ZINC35328050 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50357713 O=C(NCCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N InChI=1S/C23H28N4O/c24-17-20-8-4-9-22(16-20)27-23(28)26-12-5-10-21-15-19(11-13-25-21)14-18-6-2-1-3-7-18/h1-4,6-9,16,19,21,25H,5,10-15H2,(H2,26,27,28)/t19-,21-/m0/s1 FFTNCZSASXDDKK-FPOVZHCZSA-N 50193762 (+)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::CHEMBL218997 C-C chemokine receptor type 3 Homo sapiens 644 ChEMBL 10.1016/j.bmcl.2006.08.012 10.7270/Q29K49VQ 16931001 Watson, PS; Jiang, B; Harrison, K; Asakawa, N; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193762&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44419314 104076158 CHEMBL218997 ZINC36093275 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381420 CC(=O)c1sc(NC(=O)N[C@@H]2CNCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H34FN5O2S/c1-16-23(17(2)32)34-25(28-16)30-24(33)29-22-13-27-10-9-20(22)15-31-11-3-4-19(14-31)12-18-5-7-21(26)8-6-18/h5-8,19-20,22,27H,3-4,9-15H2,1-2H3,(H2,28,29,30,33)/t19-,20-,22+/m0/s1 MYZPVKYKKLUOPV-JAXLGGSGSA-N 50209972 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251079 C-C chemokine receptor type 3 Homo sapiens 2.1 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209972&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445847 104086618 CHEMBL251079 ZINC28975182 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381421 CC(=O)c1sc(NC(=O)N[C@@H]2CNC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C24H32FN5O2S/c1-15-22(16(2)31)33-24(27-15)29-23(32)28-21-12-26-11-19(21)14-30-9-3-4-18(13-30)10-17-5-7-20(25)8-6-17/h5-8,18-19,21,26H,3-4,9-14H2,1-2H3,(H2,27,28,29,32)/t18-,19-,21+/m0/s1 XLRNYRPKEKOVGJ-IRFCIJBXSA-N 50209970 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)pyrrolidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249056 C-C chemokine receptor type 3 Homo sapiens 7.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209970&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445850 104086616 CHEMBL249056 ZINC28975203 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381426 CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-16-33(19(3)35)12-10-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 ZFRLEPMXXGKKBN-WPFOTENUSA-N 50209974 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249854 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209974&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11953409 104086620 CHEMBL249854 ZINC28975388 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381427 CN1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C26H36FN5O2S/c1-17-24(18(2)33)35-26(28-17)30-25(34)29-23-10-12-31(3)15-21(23)16-32-11-4-5-20(14-32)13-19-6-8-22(27)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H2,28,29,30,34)/t20-,21-,23+/m0/s1 CRSGHEPGTAUWJO-QNWVGRARSA-N 50209976 1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249060 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209976&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445876 104086622 CHEMBL249060 ZINC28975356 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381430 CC(=O)c1sc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C26H35FN4O2S/c1-17-24(18(2)32)34-26(28-17)30-25(33)29-23-8-4-3-7-21(23)16-31-13-5-6-20(15-31)14-19-9-11-22(27)12-10-19/h9-12,20-21,23H,3-8,13-16H2,1-2H3,(H2,28,29,30,33)/t20-,21-,23+/m0/s1 NDZYPHLNJZSQJY-QNWVGRARSA-N 50163636 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-Acetyl-4-methyl-thiazol-2-yl)-3-{(1R,2S)-2-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-urea::CHEMBL195433 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11329244 104049619 CHEMBL195433 ZINC13613346 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381434 CC(C)C(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C29H40FN5O3S/c1-18(2)27(37)35-13-11-23(16-34-12-5-6-22(15-34)14-21-7-9-24(30)10-8-21)25(17-35)32-28(38)33-29-31-19(3)26(39-29)20(4)36/h7-10,18,22-23,25H,5-6,11-17H2,1-4H3,(H2,31,32,33,38)/t22-,23-,25+/m0/s1 WYEYLXCZEJWTGK-SONWIMMPSA-N 50209980 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-isobutyrylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL399150 C-C chemokine receptor type 3 Homo sapiens 2.1 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209980&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445878 104086626 CHEMBL399150 ZINC28975370 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381435 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(CC#N)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H35FN6O2S/c1-18-25(19(2)35)37-27(30-18)32-26(36)31-24-9-12-33(13-10-29)16-22(24)17-34-11-3-4-21(15-34)14-20-5-7-23(28)8-6-20/h5-8,21-22,24H,3-4,9,11-17H2,1-2H3,(H2,30,31,32,36)/t21-,22-,24+/m0/s1 JIVLHFRCJCETBI-WPFOTENUSA-N 50209979 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyanomethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL250437 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209979&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445867 104086625 CHEMBL250437 ZINC28975306 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381436 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CCOCC2)nc1C InChI=1S/C31H42FN5O4S/c1-20-28(21(2)38)42-31(33-20)35-30(40)34-27-9-13-37(29(39)24-10-14-41-15-11-24)19-25(27)18-36-12-3-4-23(17-36)16-22-5-7-26(32)8-6-22/h5-8,23-25,27H,3-4,9-19H2,1-2H3,(H2,33,34,35,40)/t23-,25+,27+/m0/s1 GXEUOMNYYYTCOF-VXQMPNGUSA-N 50209981 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL403742 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209981&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445915 104086627 CHEMBL403742 ZINC28975519 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381441 CN(C)CC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C29H41FN6O3S/c1-19-27(20(2)37)40-29(31-19)33-28(39)32-25-11-13-36(26(38)18-34(3)4)17-23(25)16-35-12-5-6-22(15-35)14-21-7-9-24(30)10-8-21/h7-10,22-23,25H,5-6,11-18H2,1-4H3,(H2,31,32,33,39)/t22-,23+,25+/m0/s1 PXRJBYSXFOWDHK-JBRSBNLGSA-N 50209983 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)acetyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL401159 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209983&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445866 104086629 CHEMBL401159 ZINC28975299 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381442 CC(=O)N1CCC(CC1)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C32H45FN6O3S/c1-21-30(22(2)40)43-32(34-21)36-31(42)35-29-12-16-39(28-10-14-38(15-11-28)23(3)41)20-26(29)19-37-13-4-5-25(18-37)17-24-6-8-27(33)9-7-24/h6-9,25-26,28-29H,4-5,10-20H2,1-3H3,(H2,34,35,36,42)/t25-,26+,29+/m0/s1 SEGSTAYQKLCBCH-IWVFXYMLSA-N 50209985 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-acetylpiperidin-4-yl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249058 C-C chemokine receptor type 3 Homo sapiens 2.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209985&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 21362416 104086631 CHEMBL249058 ZINC28975339 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381443 CN1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C26H36FN5O2S/c1-17-24(18(2)33)35-26(28-17)30-25(34)29-23-16-31(3)12-10-21(23)15-32-11-4-5-20(14-32)13-19-6-8-22(27)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H2,28,29,30,34)/t20-,21-,23+/m0/s1 HAOJBCWTKNVFJG-QNWVGRARSA-N 50209984 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-acetyl-4-methylthiazol-2-yl)-3-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-3-yl)urea::CHEMBL410959 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209984&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445901 104086630 CHEMBL410959 ZINC28975463 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381444 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CCO)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H38FN5O3S/c1-18-25(19(2)35)37-27(29-18)31-26(36)30-24-17-32(12-13-34)11-9-22(24)16-33-10-3-4-21(15-33)14-20-5-7-23(28)8-6-20/h5-8,21-22,24,34H,3-4,9-17H2,1-2H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 FQLXRHMQZQJNRK-WPFOTENUSA-N 50209986 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-hydroxyethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL399088 C-C chemokine receptor type 3 Homo sapiens 2.8 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209986&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445896 104086632 CHEMBL399088 ZINC28975460 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396477 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)C(=O)NC(C)(C)C)c(C)c1 InChI=1S/C26H33F3N4O3/c1-16-9-10-19(17(2)11-16)13-30-14-21(24(36)33-25(3,4)5)32-22(34)15-31-23(35)18-7-6-8-20(12-18)26(27,28)29/h6-12,21,30H,13-15H2,1-5H3,(H,31,35)(H,32,34)(H,33,36)/t21-/m0/s1 LHLMXUIIDZMSKK-NRFANRHFSA-N 50219835 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide::CHEMBL400196 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219835&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10164316 104092958 CHEMBL400196 ZINC03976775 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396478 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cc(ccc2NCc2ccccc2)C(F)(F)F)C(=O)NC(C)(C)C)c(C)c1 InChI=1S/C33H40F3N5O3/c1-21-11-12-24(22(2)15-21)18-37-19-28(31(44)41-32(3,4)5)40-29(42)20-39-30(43)26-16-25(33(34,35)36)13-14-27(26)38-17-23-9-7-6-8-10-23/h6-16,28,37-38H,17-20H2,1-5H3,(H,39,43)(H,40,42)(H,41,44)/t28-/m0/s1 RATLHLFNSBYGID-NDEPHWFRSA-N 50219837 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-(benzylamino)-5-(trifluoromethyl)benzamide::CHEMBL247608 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219837&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442587 104092960 CHEMBL247608 ZINC28952445 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396489 CCNc1cc(cc(c1)C(F)(F)F)C(=O)NCC(=O)N[C@@H](CNCc1ccc(C)cc1C)C(=O)NC(C)(C)C InChI=1S/C28H38F3N5O3/c1-7-33-22-12-20(11-21(13-22)28(29,30)31)25(38)34-16-24(37)35-23(26(39)36-27(4,5)6)15-32-14-19-9-8-17(2)10-18(19)3/h8-13,23,32-33H,7,14-16H2,1-6H3,(H,34,38)(H,35,37)(H,36,39)/t23-/m0/s1 DSFQNRDBSSXAGS-QHCPKHFHSA-N 50219847 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(ethylamino)-5-(trifluoromethyl)benzamide::CHEMBL392814 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219847&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442593 104092970 CHEMBL392814 ZINC28952458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396501 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cccc(c2N)C(F)(F)F)C(N)=O)c(C)c1 InChI=1S/C22H26F3N5O3/c1-12-6-7-14(13(2)8-12)9-28-10-17(20(27)32)30-18(31)11-29-21(33)15-4-3-5-16(19(15)26)22(23,24)25/h3-8,17,28H,9-11,26H2,1-2H3,(H2,27,32)(H,29,33)(H,30,31)/t17-/m0/s1 FPRGMDNECUUAFV-KRWDZBQOSA-N 50219857 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-amino-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-3-(trifluoromethyl)benzamide::CHEMBL398747 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219857&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442598 104092980 CHEMBL398747 ZINC28952468 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396512 CCNc1ccc(cc1C(=O)NCC(=O)N[C@@H](CNCc1ccc(C)cc1C)C(=O)NC(C)(C)C)C(F)(F)F InChI=1S/C28H38F3N5O3/c1-7-33-22-11-10-20(28(29,30)31)13-21(22)25(38)34-16-24(37)35-23(26(39)36-27(4,5)6)15-32-14-19-9-8-17(2)12-18(19)3/h8-13,23,32-33H,7,14-16H2,1-6H3,(H,34,38)(H,35,37)(H,36,39)/t23-/m0/s1 ONYNFACZHHCTDA-QHCPKHFHSA-N 50219840 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-(ethylamino)-5-(trifluoromethyl)benzamide::CHEMBL393267 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219840&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10187492 104092963 CHEMBL393267 ZINC28952444 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396524 CC(C)NC(=O)Nc1ccc(cc1C(=O)NCC(=O)N[C@@H](CNCc1ccc(C)cc1C)C(=O)NC(C)(C)C)C(F)(F)F InChI=1S/C30H41F3N6O4/c1-17(2)36-28(43)38-23-11-10-21(30(31,32)33)13-22(23)26(41)35-16-25(40)37-24(27(42)39-29(5,6)7)15-34-14-20-9-8-18(3)12-19(20)4/h8-13,17,24,34H,14-16H2,1-7H3,(H,35,41)(H,37,40)(H,39,42)(H2,36,38,43)/t24-/m0/s1 AWJUKDQERXTXHY-DEOSSOPVSA-N 50219850 (S)-1-(2-((2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)carbamoyl)-4-(trifluoromethyl)phenyl)-3-isopropylurea::CHEMBL247455 C-C chemokine receptor type 3 Homo sapiens 10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219850&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442590 104092973 CHEMBL247455 ZINC28952452 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381447 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)OC(C)(C)C)nc1C InChI=1S/C30H42FN5O4S/c1-19-26(20(2)37)41-28(32-19)34-27(38)33-25-12-14-36(29(39)40-30(3,4)5)18-23(25)17-35-13-6-7-22(16-35)15-21-8-10-24(31)11-9-21/h8-11,22-23,25H,6-7,12-18H2,1-5H3,(H2,32,33,34,38)/t22-,23+,25+/m0/s1 RJECZNRGVJPLSQ-JBRSBNLGSA-N 50209987 (3R,4R)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate::CHEMBL250054 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209987&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445843 104086633 CHEMBL250054 ZINC28975167 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381448 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(CCF)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H37F2N5O2S/c1-18-25(19(2)35)37-27(30-18)32-26(36)31-24-9-12-33(13-10-28)16-22(24)17-34-11-3-4-21(15-34)14-20-5-7-23(29)8-6-20/h5-8,21-22,24H,3-4,9-17H2,1-2H3,(H2,30,31,32,36)/t21-,22-,24+/m0/s1 CCWUAAILIWKHIU-WPFOTENUSA-N 50209988 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-fluoroethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251622 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209988&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445872 104086634 CHEMBL251622 ZINC28975324 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381453 CCNC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C28H39FN6O3S/c1-4-30-28(38)35-13-11-24(32-26(37)33-27-31-18(2)25(39-27)19(3)36)22(17-35)16-34-12-5-6-21(15-34)14-20-7-9-23(29)10-8-20/h7-10,21-22,24H,4-6,11-17H2,1-3H3,(H,30,38)(H2,31,32,33,37)/t21-,22+,24+/m0/s1 WKMAJEHBPREIER-WMTXJRDZSA-N 50209993 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(ethylcarbamoyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251446 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209993&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445864 104086639 CHEMBL251446 ZINC28975289 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381455 CC(=O)c1cccc(NC(=O)N\C=C\CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H28FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,4,6-12,16,20H,3,5,13-15,17H2,1H3,(H2,26,27,30)/b12-4+/t20-/m0/s1 DHVVNENKLSLVOC-JEFHHPKPSA-N 50209996 (S,E)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)prop-1-enyl)-3-(3-acetylphenyl)urea::CHEMBL253676 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209996&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445907 104086642 CHEMBL253676 ZINC28975469 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381459 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(CC3CC3)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C29H40FN5O2S/c1-19-27(20(2)36)38-29(31-19)33-28(37)32-26-11-13-35(15-22-5-6-22)18-24(26)17-34-12-3-4-23(16-34)14-21-7-9-25(30)10-8-21/h7-10,22-24,26H,3-6,11-18H2,1-2H3,(H2,31,32,33,37)/t23-,24+,26+/m0/s1 GIMZSPHDTTYQLI-BFLUCZKCSA-N 50210000 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropylmethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251623 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210000&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445874 104086646 CHEMBL251623 ZINC28975333 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381460 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CCCC2)nc1C InChI=1S/C31H42FN5O3S/c1-20-28(21(2)38)41-31(33-20)35-30(40)34-27-13-15-37(29(39)24-7-3-4-8-24)19-25(27)18-36-14-5-6-23(17-36)16-22-9-11-26(32)12-10-22/h9-12,23-25,27H,3-8,13-19H2,1-2H3,(H2,33,34,35,40)/t23-,25+,27+/m0/s1 VZAFNNYJNKDUHB-VXQMPNGUSA-N 50209997 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopentanecarbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL400172 C-C chemokine receptor type 3 Homo sapiens 2.9 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209997&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445855 104086643 CHEMBL400172 ZINC28975235 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381462 CC(=O)c1sc(NC(=O)N[C@@H]2CS(=O)(=O)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C24H31FN4O4S2/c1-15-22(16(2)30)34-24(26-15)28-23(31)27-21-14-35(32,33)13-19(21)12-29-9-3-4-18(11-29)10-17-5-7-20(25)8-6-17/h5-8,18-19,21H,3-4,9-14H2,1-2H3,(H2,26,27,28,31)/t18-,19+,21+/m0/s1 IRBQOVMCXICGDZ-QKNQBKEWSA-N 50209999 1-(5-acetyl-4-methyl-thiazol-2-yl)-3-{(3S,4S)-4-[(S)-3-(4-fluoro-benzyl)-piperidin-1-ylmethyl]-1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl}-urea::CHEMBL249057 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209999&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445854 104086645 CHEMBL249057 ZINC28975225 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381463 CC(=O)c1sc(NC(=O)N[C@@H]2CN(C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)OC(C)(C)C)nc1C InChI=1S/C29H40FN5O4S/c1-18-25(19(2)36)40-27(31-18)33-26(37)32-24-17-35(28(38)39-29(3,4)5)16-22(24)15-34-12-6-7-21(14-34)13-20-8-10-23(30)11-9-20/h8-11,21-22,24H,6-7,12-17H2,1-5H3,(H2,31,32,33,37)/t21-,22+,24+/m0/s1 HUEIIQRYVMJFKL-WMTXJRDZSA-N 50209998 (3R,4S)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)pyrrolidine-1-carboxylate::CHEMBL251243 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209998&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445849 104086644 CHEMBL251243 ZINC28975198 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381464 CC(=O)N1CCC(CC1)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C32H45FN6O3S/c1-21-30(22(2)40)43-32(34-21)36-31(42)35-29-20-39(28-11-15-38(16-12-28)23(3)41)14-10-26(29)19-37-13-4-5-25(18-37)17-24-6-8-27(33)9-7-24/h6-9,25-26,28-29H,4-5,10-20H2,1-3H3,(H2,34,35,36,42)/t25-,26-,29+/m0/s1 GQPVTPBVODGSBT-QXTIUPHPSA-N 50210001 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-acetylpiperidin-4-yl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL399893 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210001&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445894 104086647 CHEMBL399893 ZINC28975447 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381466 CN(C)CC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C29H41FN6O3S/c1-19-27(20(2)37)40-29(31-19)33-28(39)32-25-17-36(26(38)18-34(3)4)13-11-23(25)16-35-12-5-6-22(15-35)14-21-7-9-24(30)10-8-21/h7-10,22-23,25H,5-6,11-18H2,1-4H3,(H2,31,32,33,39)/t22-,23-,25+/m0/s1 NBEYIKPRTIBJBG-SONWIMMPSA-N 50209995 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)acetyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249858 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209995&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445887 104086641 CHEMBL249858 ZINC28975411 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381468 COC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H36FN5O4S/c1-17-24(18(2)34)38-26(29-17)31-25(35)30-23-16-33(27(36)37-3)12-10-21(23)15-32-11-4-5-20(14-32)13-19-6-8-22(28)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H2,29,30,31,35)/t20-,21-,23+/m0/s1 LZPOCRZQAOZURJ-QNWVGRARSA-N 50209994 (3S,4S)-methyl 4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate::CHEMBL249852 C-C chemokine receptor type 3 Homo sapiens 4.9 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209994&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445879 104086640 CHEMBL249852 ZINC28975375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381472 CC(=O)c1sc(NC(=O)N[C@@H]2CN(Cc3ccco3)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C30H38FN5O3S/c1-20-28(21(2)37)40-30(32-20)34-29(38)33-27-19-36(18-26-6-4-14-39-26)13-11-24(27)17-35-12-3-5-23(16-35)15-22-7-9-25(31)10-8-22/h4,6-10,14,23-24,27H,3,5,11-13,15-19H2,1-2H3,(H2,32,33,34,38)/t23-,24-,27+/m0/s1 XDFZDZYPEKUXKO-NLJOTIRTSA-N 50210003 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(furan-2-ylmethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL400649 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210003&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445889 104086649 CHEMBL400649 ZINC28975423 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381474 CC(=O)c1sc(NC(=O)N[C@@H]2COCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H33FN4O3S/c1-16-23(17(2)31)34-25(27-16)29-24(32)28-22-15-33-11-9-20(22)14-30-10-3-4-19(13-30)12-18-5-7-21(26)8-6-18/h5-8,19-20,22H,3-4,9-15H2,1-2H3,(H2,27,28,29,32)/t19-,20-,22+/m0/s1 JMTZNRURKTUFTP-JAXLGGSGSA-N 50210006 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL404416 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210006&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445842 104086652 CHEMBL404416 ZINC28975161 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381478 CC(C)C(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C29H40FN5O3S/c1-18(2)27(37)35-13-11-25(32-28(38)33-29-31-19(3)26(39-29)20(4)36)23(17-35)16-34-12-5-6-22(15-34)14-21-7-9-24(30)10-8-21/h7-10,18,22-23,25H,5-6,11-17H2,1-4H3,(H2,31,32,33,38)/t22-,23+,25+/m0/s1 IWKLYINHWTWPNC-JBRSBNLGSA-N 50210014 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-isobutyrylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL250262 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210014&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445856 104086660 CHEMBL250262 ZINC28975241 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381479 CNC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C27H37FN6O3S/c1-17-24(18(2)35)38-26(30-17)32-25(36)31-23-10-12-34(27(37)29-3)16-21(23)15-33-11-4-5-20(14-33)13-19-6-8-22(28)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H,29,37)(H2,30,31,32,36)/t20-,21+,23+/m0/s1 TXFKRSLQBDPWHK-QZNHQXDQSA-N 50210007 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(methylcarbamoyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL400589 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210007&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445865 104086653 CHEMBL400589 ZINC28975294 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381481 CC(=O)CN1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C28H38FN5O3S/c1-18(35)14-34-12-10-23(16-33-11-4-5-22(15-33)13-21-6-8-24(29)9-7-21)25(17-34)31-27(37)32-28-30-19(2)26(38-28)20(3)36/h6-9,22-23,25H,4-5,10-17H2,1-3H3,(H2,30,31,32,37)/t22-,23-,25+/m0/s1 UNLORHRTORLFAX-SONWIMMPSA-N 50210015 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-oxopropyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL401115 C-C chemokine receptor type 3 Homo sapiens 6.9 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210015&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445890 104086661 CHEMBL401115 ZINC28975427 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381483 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CCF)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H37F2N5O2S/c1-18-25(19(2)35)37-27(30-18)32-26(36)31-24-17-33(13-10-28)12-9-22(24)16-34-11-3-4-21(15-34)14-20-5-7-23(29)8-6-20/h5-8,21-22,24H,3-4,9-17H2,1-2H3,(H2,30,31,32,36)/t21-,22-,24+/m0/s1 KPAYEHBENMIRQR-WPFOTENUSA-N 50209991 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-fluoroethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251044 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209991&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445891 104086637 CHEMBL251044 ZINC28975433 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381485 COCC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C28H38FN5O4S/c1-18-26(19(2)35)39-28(30-18)32-27(37)31-24-10-12-34(25(36)17-38-3)16-22(24)15-33-11-4-5-21(14-33)13-20-6-8-23(29)9-7-20/h6-9,21-22,24H,4-5,10-17H2,1-3H3,(H2,30,31,32,37)/t21-,22+,24+/m0/s1 KAJGDDHQBLSIIE-WMTXJRDZSA-N 50210009 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-methoxyacetyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251275 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210009&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445863 104086655 CHEMBL251275 ZINC28975283 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381489 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(CCO)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H38FN5O3S/c1-18-25(19(2)35)37-27(29-18)31-26(36)30-24-9-11-32(12-13-34)16-22(24)17-33-10-3-4-21(15-33)14-20-5-7-23(28)8-6-20/h5-8,21-22,24,34H,3-4,9-17H2,1-2H3,(H2,29,30,31,36)/t21-,22-,24+/m0/s1 OCOUSFGWGHCEPX-WPFOTENUSA-N 50210008 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-hydroxyethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249059 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210008&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445875 104086654 CHEMBL249059 ZINC28975351 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381490 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CC2)nc1C InChI=1S/C29H38FN5O3S/c1-18-26(19(2)36)39-29(31-18)33-28(38)32-25-17-35(27(37)22-7-8-22)13-11-23(25)16-34-12-3-4-21(15-34)14-20-5-9-24(30)10-6-20/h5-6,9-10,21-23,25H,3-4,7-8,11-17H2,1-2H3,(H2,31,32,33,38)/t21-,23-,25+/m0/s1 QYZCRHUUDLMPAO-UMXIMWEHSA-N 50209978 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropanecarbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL402708 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209978&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445883 104086624 CHEMBL402708 ZINC28975386 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381492 CC(=O)CN1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C28H38FN5O3S/c1-18(35)14-34-12-10-25(31-27(37)32-28-30-19(2)26(38-28)20(3)36)23(17-34)16-33-11-4-5-22(15-33)13-21-6-8-24(29)9-7-21/h6-9,22-23,25H,4-5,10-17H2,1-3H3,(H2,30,31,32,37)/t22-,23+,25+/m0/s1 KQPUQEUKQSELDJ-JBRSBNLGSA-N 50210004 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-oxopropyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL429303 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210004&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445870 104086650 CHEMBL429303 ZINC28975318 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381493 CC(=O)c1sc(NC(=O)N[C@@H]2CNC[C@@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C24H32FN5O2S/c1-15-22(16(2)31)33-24(27-15)29-23(32)28-21-12-26-11-19(21)14-30-9-3-4-18(13-30)10-17-5-7-20(25)8-6-17/h5-8,18-19,21,26H,3-4,9-14H2,1-2H3,(H2,27,28,29,32)/t18-,19+,21+/m0/s1 XLRNYRPKEKOVGJ-QKNQBKEWSA-N 50210010 1-((3S,4R)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)pyrrolidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL399134 C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210010&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445853 104086656 CHEMBL399134 ZINC28975216 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381499 COCC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C28H38FN5O4S/c1-18-26(19(2)35)39-28(30-18)32-27(37)31-24-16-34(25(36)17-38-3)12-10-22(24)15-33-11-4-5-21(14-33)13-20-6-8-23(29)9-7-20/h6-9,21-22,24H,4-5,10-17H2,1-3H3,(H2,30,31,32,37)/t21-,22-,24+/m0/s1 IWCDKJNLRKTQFJ-WPFOTENUSA-N 50210016 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-methoxyacetyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249855 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210016&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445884 104086662 CHEMBL249855 ZINC28975394 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381500 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC3CC3)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C29H40FN5O2S/c1-19-27(20(2)36)38-29(31-19)33-28(37)32-26-18-35(15-22-5-6-22)13-11-24(26)17-34-12-3-4-23(16-34)14-21-7-9-25(30)10-8-21/h7-10,22-24,26H,3-6,11-18H2,1-2H3,(H2,31,32,33,37)/t23-,24-,26+/m0/s1 BGRYRZFRZVJJFE-KYPHJKQUSA-N 50210021 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropylmethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL398889 C-C chemokine receptor type 3 Homo sapiens 2.7 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445893 104086667 CHEMBL398889 ZINC28975443 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381503 CC(=O)c1sc(NC(=O)N[C@@H]2CCCO[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H33FN4O3S/c1-16-23(17(2)31)34-25(27-16)29-24(32)28-21-6-4-12-33-22(21)15-30-11-3-5-19(14-30)13-18-7-9-20(26)10-8-18/h7-10,19,21-22H,3-6,11-15H2,1-2H3,(H2,27,28,29,32)/t19-,21+,22-/m0/s1 JJILEQNLSXCPPS-NNWRFLSQSA-N 50210022 1-((2S,3R)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL404213 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210022&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445839 104086668 CHEMBL404213 ZINC28975150 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381509 CN1CCC(CC1)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C31H45FN6O2S/c1-21-29(22(2)39)41-31(33-21)35-30(40)34-28-20-38(27-11-14-36(3)15-12-27)16-10-25(28)19-37-13-4-5-24(18-37)17-23-6-8-26(32)9-7-23/h6-9,24-25,27-28H,4-5,10-20H2,1-3H3,(H2,33,34,35,40)/t24-,25-,28+/m0/s1 DUQPPLUAQADJCL-PNIUZAESSA-N 50210023 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-methylpiperidin-4-yl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251220 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210023&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445895 104086669 CHEMBL251220 ZINC28975453 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381511 CCNC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C28H39FN6O3S/c1-4-30-28(38)35-13-11-22(16-34-12-5-6-21(15-34)14-20-7-9-23(29)10-8-20)24(17-35)32-26(37)33-27-31-18(2)25(39-27)19(3)36/h7-10,21-22,24H,4-6,11-17H2,1-3H3,(H,30,38)(H2,31,32,33,37)/t21-,22-,24+/m0/s1 PBDIBHOSSWBUEA-WPFOTENUSA-N 50210020 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(ethylcarbamoyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL439253 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210020&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445885 104086666 CHEMBL439253 ZINC28975399 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381512 CNC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C27H37FN6O3S/c1-17-24(18(2)35)38-26(30-17)32-25(36)31-23-16-34(27(37)29-3)12-10-21(23)15-33-11-4-5-20(14-33)13-19-6-8-22(28)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H,29,37)(H2,30,31,32,36)/t20-,21-,23+/m0/s1 AYMZHWSWFBAEIT-QNWVGRARSA-N 50209982 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(methylcarbamoyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249857 C-C chemokine receptor type 3 Homo sapiens 0.600000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209982&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445886 104086628 CHEMBL249857 ZINC28975406 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381514 CCC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C28H38FN5O3S/c1-4-25(36)34-13-11-22(16-33-12-5-6-21(15-33)14-20-7-9-23(29)10-8-20)24(17-34)31-27(37)32-28-30-18(2)26(38-28)19(3)35/h7-10,21-22,24H,4-6,11-17H2,1-3H3,(H2,30,31,32,37)/t21-,22-,24+/m0/s1 FCEGPTNQXBCGQY-WPFOTENUSA-N 50209992 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-propionylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL402707 C-C chemokine receptor type 3 Homo sapiens 2.1 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209992&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445880 104086638 CHEMBL402707 ZINC28975381 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396559 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)C(N)=O)c(C)c1 InChI=1S/C22H25F3N4O3/c1-13-6-7-16(14(2)8-13)10-27-11-18(20(26)31)29-19(30)12-28-21(32)15-4-3-5-17(9-15)22(23,24)25/h3-9,18,27H,10-12H2,1-2H3,(H2,26,31)(H,28,32)(H,29,30)/t18-/m0/s1 KEUFKEFYFXTLDW-SFHVURJKSA-N 50219898 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-amino-1-oxopropan-2-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide::CHEMBL248418 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219898&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10182382 104093021 CHEMBL248418 ZINC28952313 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396571 Cc1cc(Br)ccc1CNC[C@H](NC(=O)CNC(=O)c1cccc(c1N)C(F)(F)F)C(=O)NC(C)(C)C InChI=1S/C25H31BrF3N5O3/c1-14-10-16(26)9-8-15(14)11-31-12-19(23(37)34-24(2,3)4)33-20(35)13-32-22(36)17-6-5-7-18(21(17)30)25(27,28)29/h5-10,19,31H,11-13,30H2,1-4H3,(H,32,36)(H,33,35)(H,34,37)/t19-/m0/s1 FQVOQFDNIZIQOT-IBGZPJMESA-N 50219842 (S)-N-(2-(3-(4-bromo-2-methylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-3-(trifluoromethyl)benzamide::CHEMBL246804 C-C chemokine receptor type 3 Homo sapiens 1500 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219842&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442599 104092965 CHEMBL246804 ZINC28952470 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396573 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)C(=O)NC(C)(C)C)c(C)c1 InChI=1S/C26H34F3N5O3/c1-15-6-7-17(16(2)10-15)12-31-13-21(24(37)34-25(3,4)5)33-22(35)14-32-23(36)19-11-18(26(27,28)29)8-9-20(19)30/h6-11,21,31H,12-14,30H2,1-5H3,(H,32,36)(H,33,35)(H,34,37)/t21-/m0/s1 JJYNUAMIRAIFBQ-NRFANRHFSA-N 50219862 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-2-amino-5-(trifluoromethyl)benzamide::CHEMBL247245 C-C chemokine receptor type 3 Homo sapiens 750 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219862&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10142792 104092985 CHEMBL247245 ZINC28952437 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50396578 Cc1ccc(CNC[C@H](NC(=O)CNC(=O)c2cc(N)cc(c2)C(F)(F)F)C(=O)NC(C)(C)C)c(C)c1 InChI=1S/C26H34F3N5O3/c1-15-6-7-17(16(2)8-15)12-31-13-21(24(37)34-25(3,4)5)33-22(35)14-32-23(36)18-9-19(26(27,28)29)11-20(30)10-18/h6-11,21,31H,12-14,30H2,1-5H3,(H,32,36)(H,33,35)(H,34,37)/t21-/m0/s1 ZEYAHFUIXMLOML-NRFANRHFSA-N 50219851 (S)-N-(2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)-3-amino-5-(trifluoromethyl)benzamide::CHEMBL247621 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.07.028 10.7270/Q29Z94NN 17720492 Carter, PH; Brown, GD; Friedrich, SR; Cherney, RJ; Tebben, AJ; Lo, YC; Yang, G; Jezak, H; Solomon, KA; Scherle, PA; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219851&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44442586 104092974 CHEMBL247621 ZINC28952439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381518 CC(=O)c1sc(NC(=O)N[C@@H]2CCNC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H34FN5O2S/c1-16-23(17(2)32)34-25(28-16)30-24(33)29-22-9-10-27-13-20(22)15-31-11-3-4-19(14-31)12-18-5-7-21(26)8-6-18/h5-8,19-20,22,27H,3-4,9-15H2,1-2H3,(H2,28,29,30,33)/t19-,20-,22+/m0/s1 YIHKVKMNPOHFTQ-JAXLGGSGSA-N 50209989 1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL250056 C-C chemokine receptor type 3 Homo sapiens 1.9 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209989&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445845 104086635 CHEMBL250056 ZINC28975173 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381520 CN(C)C(=O)CN1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C29H41FN6O3S/c1-19-27(20(2)37)40-29(31-19)33-28(39)32-25-11-13-36(18-26(38)34(3)4)17-23(25)16-35-12-5-6-22(15-35)14-21-7-9-24(30)10-8-21/h7-10,22-23,25H,5-6,11-18H2,1-4H3,(H2,31,32,33,39)/t22-,23+,25+/m0/s1 UWCQUWYSAPGJBW-JBRSBNLGSA-N 50210005 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)-2-oxoethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL401160 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210005&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445873 104086651 CHEMBL401160 ZINC28975327 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381523 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381525 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.700000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381526 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CC2)nc1C InChI=1S/C29H38FN5O3S/c1-18-26(19(2)36)39-29(31-18)33-28(38)32-25-11-13-35(27(37)22-7-8-22)17-23(25)16-34-12-3-4-21(15-34)14-20-5-9-24(30)10-6-20/h5-6,9-10,21-23,25H,3-4,7-8,11-17H2,1-2H3,(H2,31,32,33,38)/t21-,23+,25+/m0/s1 RRVDFHOPPCFMQT-QQKQFIJSSA-N 50209990 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopropanecarbonyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251274 C-C chemokine receptor type 3 Homo sapiens 3.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209990&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445862 104086636 CHEMBL251274 ZINC28975271 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381531 CC(=O)c1sc(NC(=O)N[C@@H]2CN(C[C@@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)OC(C)(C)C)nc1C InChI=1S/C29H40FN5O4S/c1-18-25(19(2)36)40-27(31-18)33-26(37)32-24-17-35(28(38)39-29(3,4)5)16-22(24)15-34-12-6-7-21(14-34)13-20-8-10-23(30)11-9-20/h8-11,21-22,24H,6-7,12-17H2,1-5H3,(H2,31,32,33,37)/t21-,22-,24+/m0/s1 HUEIIQRYVMJFKL-WPFOTENUSA-N 50209977 (3S,4S)-tert-butyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)pyrrolidine-1-carboxylate::CHEMBL399133 C-C chemokine receptor type 3 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209977&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445851 104086623 CHEMBL399133 ZINC28975210 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381532 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CCCC2)nc1C InChI=1S/C31H42FN5O3S/c1-20-28(21(2)38)41-31(33-20)35-30(40)34-27-19-37(29(39)24-7-3-4-8-24)15-13-25(27)18-36-14-5-6-23(17-36)16-22-9-11-26(32)12-10-22/h9-12,23-25,27H,3-8,13-19H2,1-2H3,(H2,33,34,35,40)/t23-,25-,27+/m0/s1 DVQYUNXWAFACOO-SCTDOJESSA-N 50210025 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyclopentanecarbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL249851 C-C chemokine receptor type 3 Homo sapiens 3.6 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210025&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445877 104086671 CHEMBL249851 ZINC28975361 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381534 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC#N)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C27H35FN6O2S/c1-18-25(19(2)35)37-27(30-18)32-26(36)31-24-17-33(13-10-29)12-9-22(24)16-34-11-3-4-21(15-34)14-20-5-7-23(28)8-6-20/h5-8,21-22,24H,3-4,9,11-17H2,1-2H3,(H2,30,31,32,36)/t21-,22-,24+/m0/s1 XLKVTYHUNRLGJS-WPFOTENUSA-N 50210019 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(cyanomethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL404857 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210019&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445888 104086665 CHEMBL404857 ZINC28975417 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381537 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)OC(C)(C)C)nc1C InChI=1S/C30H42FN5O4S/c1-19-26(20(2)37)41-28(32-19)34-27(38)33-25-18-36(29(39)40-30(3,4)5)14-12-23(25)17-35-13-6-7-22(16-35)15-21-8-10-24(31)11-9-21/h8-11,22-23,25H,6-7,12-18H2,1-5H3,(H2,32,33,34,38)/t22-,23-,25+/m0/s1 ULFGYOICMCABPV-SONWIMMPSA-N 50210013 (3S,4S)-tert-butyl 4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate::CHEMBL251078 C-C chemokine receptor type 3 Homo sapiens 9.2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210013&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445846 104086659 CHEMBL251078 ZINC28975177 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381539 CCC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C28H38FN5O3S/c1-4-25(36)34-13-11-24(31-27(37)32-28-30-18(2)26(38-28)19(3)35)22(17-34)16-33-12-5-6-21(15-33)14-20-7-9-23(29)10-8-20/h7-10,21-22,24H,4-6,11-17H2,1-3H3,(H2,30,31,32,37)/t21-,22+,24+/m0/s1 VUHMEMLHQJXDJC-WMTXJRDZSA-N 50210024 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-propionylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL250436 C-C chemokine receptor type 3 Homo sapiens 3.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210024&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445861 104086670 CHEMBL250436 ZINC28975267 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381541 CN(C)C(=O)CN1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C29H41FN6O3S/c1-19-27(20(2)37)40-29(31-19)33-28(39)32-25-17-36(18-26(38)34(3)4)13-11-23(25)16-35-12-5-6-22(15-35)14-21-7-9-24(30)10-8-21/h7-10,22-23,25H,5-6,11-18H2,1-4H3,(H2,31,32,33,39)/t22-,23-,25+/m0/s1 XKTJOAIQIBMZJU-SONWIMMPSA-N 50210017 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(2-(dimethylamino)-2-oxoethyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251045 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210017&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445892 104086663 CHEMBL251045 ZINC28975439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381547 CC(=O)c1sc(NC(=O)N[C@@H]2CCN(Cc3ccco3)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C30H38FN5O3S/c1-20-28(21(2)37)40-30(32-20)34-29(38)33-27-11-13-36(19-26-6-4-14-39-26)18-24(27)17-35-12-3-5-23(16-35)15-22-7-9-25(31)10-8-22/h4,6-10,14,23-24,27H,3,5,11-13,15-19H2,1-2H3,(H2,32,33,34,38)/t23-,24+,27+/m0/s1 FRPOMOOESVDDAO-CLCZQPDDSA-N 50210002 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(furan-2-ylmethyl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL428761 C-C chemokine receptor type 3 Homo sapiens 0.900000 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210002&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445868 104086648 CHEMBL428761 ZINC28975312 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381550 CC(=O)c1sc(NC(=O)N[C@@H]2CN(CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C(=O)C2CCOCC2)nc1C InChI=1S/C31H42FN5O4S/c1-20-28(21(2)38)42-31(33-20)35-30(40)34-27-19-37(29(39)24-10-14-41-15-11-24)13-9-25(27)18-36-12-3-4-23(17-36)16-22-5-7-26(32)8-6-22/h5-8,23-25,27H,3-4,9-19H2,1-2H3,(H2,33,34,35,40)/t23-,25-,27+/m0/s1 ABTYEFIQKNTICU-SCTDOJESSA-N 50209973 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL403743 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209973&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445916 104086619 CHEMBL403743 ZINC28975525 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381553 CC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C27H36FN5O3S/c1-17-25(18(2)34)37-27(29-17)31-26(36)30-24-10-12-33(19(3)35)16-22(24)15-32-11-4-5-21(14-32)13-20-6-8-23(28)9-7-20/h6-9,21-22,24H,4-5,10-16H2,1-3H3,(H2,29,30,31,36)/t21-,22+,24+/m0/s1 VAPZFBXTIPERDF-WMTXJRDZSA-N 50210018 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-acetylpiperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL400588 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210018&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 16747712 104086664 CHEMBL400588 ZINC28975277 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381557 CC(=O)c1sc(NC(=O)N[C@@H]2CCOC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C InChI=1S/C25H33FN4O3S/c1-16-23(17(2)31)34-25(27-16)29-24(32)28-22-9-11-33-15-20(22)14-30-10-3-4-19(13-30)12-18-5-7-21(26)8-6-18/h5-8,19-20,22H,3-4,9-15H2,1-2H3,(H2,27,28,29,32)/t19-,20+,22+/m0/s1 COHCCHMMIZLJTB-TUNNFDKTSA-N 50210011 1-((3S,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-tetrahydro-2H-pyran-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL251232 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210011&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445840 104086657 CHEMBL251232 ZINC28975156 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381558 COC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C27H36FN5O4S/c1-17-24(18(2)34)38-26(29-17)31-25(35)30-23-10-12-33(27(36)37-3)16-21(23)15-32-11-4-5-20(14-32)13-19-6-8-22(28)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H2,29,30,31,35)/t20-,21+,23+/m0/s1 DHQXUOIIIYPFBB-QZNHQXDQSA-N 50210012 (3R,4R)-methyl 3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-4-(3-(5-acetyl-4-methylthiazol-2-yl)ureido)piperidine-1-carboxylate::CHEMBL400173 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210012&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445859 104086658 CHEMBL400173 ZINC28975255 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50381559 CN1CCC(CC1)N1CC[C@@H](NC(=O)Nc2nc(C)c(s2)C(C)=O)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 InChI=1S/C31H45FN6O2S/c1-21-29(22(2)39)41-31(33-21)35-30(40)34-28-12-16-38(27-10-14-36(3)15-11-27)20-25(28)19-37-13-4-5-24(18-37)17-23-6-8-26(32)9-7-23/h6-9,24-25,27-28H,4-5,10-20H2,1-3H3,(H2,33,34,35,40)/t24-,25+,28+/m0/s1 IATQFPFNGNYBPW-BXTSTYNKSA-N 50209975 1-((3R,4R)-3-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-(1-methylpiperidin-4-yl)piperidin-4-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::CHEMBL401394 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.03.065 10.7270/Q2V987SQ 17418570 Pruitt, JR; Batt, DG; Wacker, DA; Bostrom, LL; Booker, SK; McLaughlin, E; Houghton, GC; Varnes, JG; Christ, DD; Covington, M; Das, AM; Davies, P; Graden, D; Kariv, I; Orlovsky, Y; Stowell, NC; Vaddi, KG; Wadman, EA; Welch, PK; Yeleswaram, S; Solomon, KA; Newton, RC; Decicco, CP; Carter, PH; Ko, SS Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209975&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 21362425 104086621 CHEMBL401394 ZINC28975345 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388106 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(cc2)C#N)n1C InChI=1S/C33H32ClF2N5O2/c1-22-28(32(42)41(38(22)2)27-12-8-24(20-37)9-13-27)21-40(17-14-23-6-10-25(34)11-7-23)26-15-18-39(19-16-26)33(43)31-29(35)4-3-5-30(31)36/h3-13,26H,14-19,21H2,1-2H3 MPHCOQSUJSBYCJ-UHFFFAOYSA-N 50214122 4-(4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-3-oxo-1H-pyrazol-2(3H)-yl)benzonitrile::CHEMBL246346 C-C chemokine receptor type 3 Homo sapiens 158 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214122&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440419 104089309 CHEMBL246346 ZINC28897767 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388107 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3 GKXOETCIZGEUHB-UHFFFAOYSA-N 50214121 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL248179 C-C chemokine receptor type 3 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214121&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440402 104089308 CHEMBL248179 ZINC28897671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388108 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccccc2)n1C InChI=1S/C32H33ClF2N4O2/c1-22-27(31(40)39(36(22)2)26-7-4-3-5-8-26)21-38(18-15-23-11-13-24(33)14-12-23)25-16-19-37(20-17-25)32(41)30-28(34)9-6-10-29(30)35/h3-14,25H,15-21H2,1-2H3 AZTSGCZWMJWVIL-UHFFFAOYSA-N 50214123 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one::CHEMBL247160 C-C chemokine receptor type 3 Homo sapiens 32 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214123&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440394 104089310 CHEMBL247160 ZINC28897636 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388109 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3 GKXOETCIZGEUHB-UHFFFAOYSA-N 50214121 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL248179 C-C chemokine receptor type 3 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214121&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440402 104089308 CHEMBL248179 ZINC28897671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388110 Cc1c(CN(CCc2ccc(cc2)[N+]([O-])=O)C2CCN(CC2)C(=O)c2c(C)ccnc2C)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C33H37FN6O4/c1-22-13-17-35-23(2)31(22)33(42)37-19-15-27(16-20-37)38(18-14-25-5-9-29(10-6-25)40(43)44)21-30-24(3)36(4)39(32(30)41)28-11-7-26(34)8-12-28/h5-13,17,27H,14-16,18-21H2,1-4H3 DPJRLWYYOBWEIH-UHFFFAOYSA-N 50214124 4-(((4-nitrophenethyl)(1-(2,4-dimethylnicotinoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL392218 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214124&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440437 104089311 CHEMBL392218 ZINC28897880 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388111 COc1ccncc1-n1n(C)c(C)c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c1=O InChI=1S/C32H34ClF2N5O3/c1-21-25(31(41)40(37(21)2)28-19-36-15-11-29(28)43-3)20-39(16-12-22-7-9-23(33)10-8-22)24-13-17-38(18-14-24)32(42)30-26(34)5-4-6-27(30)35/h4-11,15,19,24H,12-14,16-18,20H2,1-3H3 RWGXMUHOOIXWAL-UHFFFAOYSA-N 50214125 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-methoxypyridin-3-yl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246766 C-C chemokine receptor type 3 Homo sapiens 250 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214125&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440427 104089312 CHEMBL246766 ZINC28897803 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388112 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(cc2)C(O)=O)n1C InChI=1S/C33H33ClF2N4O4/c1-21-27(31(41)40(37(21)2)26-12-8-23(9-13-26)33(43)44)20-39(17-14-22-6-10-24(34)11-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3,(H,43,44) ZXHFDDRSACRPPE-UHFFFAOYSA-N 50214126 4-(4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-3-oxo-1H-pyrazol-2(3H)-yl)benzoic acid::CHEMBL246348 C-C chemokine receptor type 3 Homo sapiens 2500 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214126&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440422 104089313 CHEMBL246348 ZINC28897784 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388113 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccccn2)n1C InChI=1S/C31H32ClF2N5O2/c1-21-25(30(40)39(36(21)2)28-8-3-4-16-35-28)20-38(17-13-22-9-11-23(32)12-10-22)24-14-18-37(19-15-24)31(41)29-26(33)6-5-7-27(29)34/h3-12,16,24H,13-15,17-20H2,1-2H3 LGAWSQIHIHBBPT-UHFFFAOYSA-N 50214127 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-2-(pyridin-2-yl)-1,2-dihydropyrazol-3-one::CHEMBL397599 C-C chemokine receptor type 3 Homo sapiens 25 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214127&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440396 104089314 CHEMBL397599 ZINC28897645 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388114 Cc1c(CN(CCc2ccccn2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C31H32F3N5O2/c1-21-26(30(40)39(36(21)2)25-11-9-22(32)10-12-25)20-38(17-13-23-6-3-4-16-35-23)24-14-18-37(19-15-24)31(41)29-27(33)7-5-8-28(29)34/h3-12,16,24H,13-15,17-20H2,1-2H3 QBWZPEOEGKGJMR-UHFFFAOYSA-N 50214128 4-(((1-(2,6-difluorobenzoyl)piperidin-4-yl)(2-(pyridin-2-yl)ethyl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL245956 C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214128&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440435 104089315 CHEMBL245956 ZINC28897871 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388115 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(Cl)cc2)n1C InChI=1S/C32H32Cl2F2N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3 SKOIKTGETGFVMV-UHFFFAOYSA-N 50214130 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-chlorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246549 C-C chemokine receptor type 3 Homo sapiens 63 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214130&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440413 104089317 CHEMBL246549 ZINC28897729 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388116 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2cccc(F)c2)n1C InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-6-3-5-24(34)19-26)20-39(16-13-22-9-11-23(33)12-10-22)25-14-17-38(18-15-25)32(42)30-28(35)7-4-8-29(30)36/h3-12,19,25H,13-18,20H2,1-2H3 ZNFLKLSUIFKNRG-UHFFFAOYSA-N 50214129 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(3-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL395090 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214129&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440411 104089316 CHEMBL395090 ZINC28897721 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388117 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(O)cc2)n1C InChI=1S/C32H33ClF2N4O3/c1-21-27(31(41)39(36(21)2)25-10-12-26(40)13-11-25)20-38(17-14-22-6-8-23(33)9-7-22)24-15-18-37(19-16-24)32(42)30-28(34)4-3-5-29(30)35/h3-13,24,40H,14-20H2,1-2H3 KQZVHXDSIRAXSF-UHFFFAOYSA-N 50214132 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-hydroxyphenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL395851 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214132&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440414 104089319 CHEMBL395851 ZINC28897734 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388118 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2cnccc2Cl)n1C InChI=1S/C31H31Cl2F2N5O2/c1-20-24(30(41)40(37(20)2)28-18-36-14-10-25(28)33)19-39(15-11-21-6-8-22(32)9-7-21)23-12-16-38(17-13-23)31(42)29-26(34)4-3-5-27(29)35/h3-10,14,18,23H,11-13,15-17,19H2,1-2H3 SMRYRNGFJDIXJL-UHFFFAOYSA-N 50214131 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-chloropyridin-3-yl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL394444 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214131&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440426 104089318 CHEMBL394444 ZINC28897798 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388119 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3 GKXOETCIZGEUHB-UHFFFAOYSA-N 50214121 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL248179 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214121&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440402 104089308 CHEMBL248179 ZINC28897671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388120 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(N)cc2)n1C InChI=1S/C32H34ClF2N5O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(36)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(34)4-3-5-29(30)35/h3-13,25H,14-20,36H2,1-2H3 AQIPJIQPPWTJAY-UHFFFAOYSA-N 50214133 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-aminophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246339 C-C chemokine receptor type 3 Homo sapiens 79 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214133&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440421 104089320 CHEMBL246339 ZINC28897778 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388121 Cc1c(CN(CCc2ccc(F)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H32F4N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3 LSNSTLHAEKDOFR-UHFFFAOYSA-N 50214135 4-(((4-fluorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246768 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214135&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440429 104089322 CHEMBL246768 ZINC28897817 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388122 Cc1c(CN(CCc2ccc(cc2)[N+]([O-])=O)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H32F3N5O4/c1-21-27(31(41)39(36(21)2)25-12-8-23(33)9-13-25)20-38(17-14-22-6-10-26(11-7-22)40(43)44)24-15-18-37(19-16-24)32(42)30-28(34)4-3-5-29(30)35/h3-13,24H,14-20H2,1-2H3 GAYJNLSIUGXPOB-UHFFFAOYSA-N 50214136 4-(((4-nitrophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL392217 C-C chemokine receptor type 3 Homo sapiens 6.3 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214136&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440431 104089323 CHEMBL392217 ZINC28897833 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388123 COc1ccc(cc1)-n1n(C)c(C)c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c1=O InChI=1S/C33H35ClF2N4O3/c1-22-28(32(41)40(37(22)2)26-11-13-27(43-3)14-12-26)21-39(18-15-23-7-9-24(34)10-8-23)25-16-19-38(20-17-25)33(42)31-29(35)5-4-6-30(31)36/h4-14,25H,15-21H2,1-3H3 JZUNRVSSTGSVKM-UHFFFAOYSA-N 50214134 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-methoxyphenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246347 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214134&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440420 104089321 CHEMBL246347 ZINC28897772 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388124 Cc1c(CN(CCc2ccc(cc2)S(N)(=O)=O)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H34F3N5O4S/c1-21-27(31(41)40(37(21)2)25-10-8-23(33)9-11-25)20-39(17-14-22-6-12-26(13-7-22)45(36,43)44)24-15-18-38(19-16-24)32(42)30-28(34)4-3-5-29(30)35/h3-13,24H,14-20H2,1-2H3,(H2,36,43,44) JXJFJFTVOXIPTM-UHFFFAOYSA-N 50214138 4-(2-((1-(2,6-difluorobenzoyl)piperidin-4-yl)((2-(4-fluorophenyl)-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)methyl)amino)ethyl)benzenesulfonamide::CHEMBL392220 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214138&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440438 104089325 CHEMBL392220 ZINC28897899 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388125 Cc1c(CN(CCc2cccnc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C31H32F3N5O2/c1-21-26(30(40)39(36(21)2)25-10-8-23(32)9-11-25)20-38(16-12-22-5-4-15-35-19-22)24-13-17-37(18-14-24)31(41)29-27(33)6-3-7-28(29)34/h3-11,15,19,24H,12-14,16-18,20H2,1-2H3 PHKHASXZEUHMMH-UHFFFAOYSA-N 50214139 4-(((1-(2,6-difluorobenzoyl)piperidin-4-yl)(2-(pyridin-3-yl)ethyl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL397853 C-C chemokine receptor type 3 Homo sapiens 2500 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214139&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440434 104089326 CHEMBL397853 ZINC28897862 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388126 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(C2CCCCC2)n1C InChI=1S/C32H39ClF2N4O2/c1-22-27(31(40)39(36(22)2)26-7-4-3-5-8-26)21-38(18-15-23-11-13-24(33)14-12-23)25-16-19-37(20-17-25)32(41)30-28(34)9-6-10-29(30)35/h6,9-14,25-26H,3-5,7-8,15-21H2,1-2H3 ZLKBASGPUKQPQI-UHFFFAOYSA-N 50214137 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-cyclohexyl-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL245310 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214137&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440398 104089324 CHEMBL245310 ZINC28897654 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388127 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2cccc[n+]2[O-])c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C31H33ClFN5O3/c1-22-28(30(39)38(34(22)2)27-12-10-25(33)11-13-27)21-36(18-14-23-6-8-24(32)9-7-23)26-15-19-35(20-16-26)31(40)29-5-3-4-17-37(29)41/h3-13,17,26H,14-16,18-21H2,1-2H3 PYOGILABXFGYCT-UHFFFAOYSA-N 50214143 4-({[2-(4-chloro-phenyl)-ethyl]-[1-(1-oxy-pyridine-2-carbonyl)-piperidin-4-yl]-amino}-methyl)-2-(4-fluoro-phenyl)-1,5-dimethyl-1,2-dihydro-pyrazol-3-one::CHEMBL392430 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214143&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440445 104089330 CHEMBL392430 ZINC28897973 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388128 Cc1c(CN(CCCCc2ccccc2)C2CCN(CC2)C(=O)c2cccc3ccccc23)c(=O)n(-c2ccccc2)n1C InChI=1S/C38H42N4O2/c1-29-36(38(44)42(39(29)2)33-19-7-4-8-20-33)28-41(25-12-11-16-30-14-5-3-6-15-30)32-23-26-40(27-24-32)37(43)35-22-13-18-31-17-9-10-21-34(31)35/h3-10,13-15,17-22,32H,11-12,16,23-28H2,1-2H3 FCRDGLPGMABUKA-UHFFFAOYSA-N 50214145 4-(((1-(1-naphthoyl)piperidin-4-yl)(4-phenylbutyl)amino)methyl)-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one::CHEMBL248178 C-C chemokine receptor type 3 Homo sapiens 158 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214145&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440393 104089332 CHEMBL248178 ZINC28897631 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388129 CC(=O)Nc1ccc(cc1)-n1n(C)c(C)c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c1=O InChI=1S/C34H36ClF2N5O3/c1-22-29(33(44)42(39(22)3)28-13-11-26(12-14-28)38-23(2)43)21-41(18-15-24-7-9-25(35)10-8-24)27-16-19-40(20-17-27)34(45)32-30(36)5-4-6-31(32)37/h4-14,27H,15-21H2,1-3H3,(H,38,43) ZDLRYSGGDYFSSN-UHFFFAOYSA-N 50214147 CHEMBL392405::N-(4-(4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-3-oxo-1H-pyrazol-2(3H)-yl)phenyl)acetamide C-C chemokine receptor type 3 Homo sapiens 400 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214147&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440423 104089334 CHEMBL392405 ZINC28897789 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388130 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(cc2)[N+]([O-])=O)n1C InChI=1S/C32H32ClF2N5O4/c1-21-27(31(41)39(36(21)2)25-10-12-26(13-11-25)40(43)44)20-38(17-14-22-6-8-23(33)9-7-22)24-15-18-37(19-16-24)32(42)30-28(34)4-3-5-29(30)35/h3-13,24H,14-20H2,1-2H3 XYQPKINWQKRNDB-UHFFFAOYSA-N 50214141 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-1,5-dimethyl-2-(4-nitrophenyl)-1,2-dihydropyrazol-3-one::CHEMBL395852 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214141&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440417 104089328 CHEMBL395852 ZINC28897752 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388131 Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccccc2F)n1C InChI=1S/C32H32ClF3N4O2/c1-21-25(31(41)40(37(21)2)29-9-4-3-6-26(29)34)20-39(17-14-22-10-12-23(33)13-11-22)24-15-18-38(19-16-24)32(42)30-27(35)7-5-8-28(30)36/h3-13,24H,14-20H2,1-2H3 CGTBCWUDBIIJEU-UHFFFAOYSA-N 50214140 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(2-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL395850 C-C chemokine receptor type 3 Homo sapiens 40 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214140&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440412 104089327 CHEMBL395850 ZINC28897726 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388132 Cc1c(CN(CCc2ccc(cc2)[N+]([O-])=O)C2CCN(CC2)C(=O)c2ccccn2)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C31H33FN6O4/c1-22-28(30(39)37(34(22)2)26-12-8-24(32)9-13-26)21-36(18-14-23-6-10-27(11-7-23)38(41)42)25-15-19-35(20-16-25)31(40)29-5-3-4-17-33-29/h3-13,17,25H,14-16,18-21H2,1-2H3 LIJGGUJVCSVBQZ-UHFFFAOYSA-N 50214142 4-(((4-nitrophenethyl)(1-picolinoylpiperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL392219 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214142&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23657036 104089329 CHEMBL392219 ZINC28897894 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388133 Cc1c(CN(CCc2ccc(N)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C InChI=1S/C32H34F3N5O2/c1-21-27(31(41)40(37(21)2)26-12-8-23(33)9-13-26)20-39(17-14-22-6-10-24(36)11-7-22)25-15-18-38(19-16-25)32(42)30-28(34)4-3-5-29(30)35/h3-13,25H,14-20,36H2,1-2H3 YKZYBXQFYKHVPD-UHFFFAOYSA-N 50214144 4-(((4-aminophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-fluorophenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL246769 C-C chemokine receptor type 3 Homo sapiens 2500 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214144&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440440 104089331 CHEMBL246769 ZINC28897910 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50388134 CN(C)c1ccc(cc1)-n1n(C)c(C)c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c1=O InChI=1S/C34H38ClF2N5O2/c1-23-29(33(43)42(39(23)4)28-14-12-26(13-15-28)38(2)3)22-41(19-16-24-8-10-25(35)11-9-24)27-17-20-40(21-18-27)34(44)32-30(36)6-5-7-31(32)37/h5-15,27H,16-22H2,1-4H3 FIFOMEQBDSUNLG-UHFFFAOYSA-N 50214146 4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)piperidin-4-yl)amino)methyl)-2-(4-(dimethylamino)phenyl)-1,5-dimethyl-1,2-dihydropyrazol-3-one::CHEMBL394443 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2007.05.035 10.7270/Q2VQ32CH 17532633 Pegurier, C; Collart, P; Danhaive, P; Defays, S; Gillard, M; Gilson, F; Kogej, T; Pasau, P; Van Houtvin, N; Van Thuyne, M; van Keulen, B UCB Pharma SA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214146&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44440424 104089333 CHEMBL394443 ZINC28897793 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408746 CCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C InChI=1S/C26H36FN7O2/c1-5-19-14-21(25-30-31-32-33(25)4)16-23(15-19)29-26(36)28-18(3)24(35)17-34(6-2)13-7-8-20-9-11-22(27)12-10-20/h9-12,14-16,18,24,35H,5-8,13,17H2,1-4H3,(H2,28,29,36)/t18-,24+/m1/s1 ZKBWRGSSTRYGHO-KOSHJBKYSA-N 50231346 1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL428062 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231346&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447382 104055077 CHEMBL428062 ZINC29039917 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408747 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)[C@@H](C)[C@@H](O)c1ccccc1 InChI=1S/C23H31N7O3/c1-15(20(31)14-29(3)16(2)21(32)17-9-6-5-7-10-17)24-23(33)25-19-12-8-11-18(13-19)22-26-27-28-30(22)4/h5-13,15-16,20-21,31-32H,14H2,1-4H3,(H2,24,25,33)/t15-,16+,20+,21-/m1/s1 BVVNIEMHJMWNCD-QMKUDKLTSA-N 50231347 1-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254503 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231347&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447361 104055078 CHEMBL254503 ZINC29039802 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408748 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)Cc2ccccc2)cc(c1)-c1nnnn1C InChI=1S/C31H38FN7O2/c1-4-23-17-26(30-35-36-37-38(30)3)19-28(18-23)34-31(41)33-22(2)29(40)21-39(20-25-9-6-5-7-10-25)16-8-11-24-12-14-27(32)15-13-24/h5-7,9-10,12-15,17-19,22,29,40H,4,8,11,16,20-21H2,1-3H3,(H2,33,34,41)/t22-,29+/m1/s1 UJUGVYFBIDUSHH-MNNSJKJDSA-N 50231348 1-((2R,3S)-4-(benzyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252792 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231348&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447154 104055079 CHEMBL252792 ZINC29039089 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408749 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-4-19-13-22(26-31-32-33-34(26)3)15-24(14-19)30-27(37)29-18(2)25(36)17-35-11-5-6-21(16-35)12-20-7-9-23(28)10-8-20/h7-10,13-15,18,21,25,36H,4-6,11-12,16-17H2,1-3H3,(H2,29,30,37)/t18-,21+,25+/m1/s1 SGWACYVRKXWJNK-QLWBXOBMSA-N 50231350 1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254930 C-C chemokine receptor type 3 Homo sapiens 0.013 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231350&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10458976 104055081 CHEMBL254930 ZINC29039931 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408750 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(CCCc1ccc(F)cc1)CC12CC3CC(CC(C3)C1)C2 InChI=1S/C33H44FN7O2/c1-22(35-32(43)36-29-7-3-6-27(16-29)31-37-38-39-40(31)2)30(42)20-41(12-4-5-23-8-10-28(34)11-9-23)21-33-17-24-13-25(18-33)15-26(14-24)19-33/h3,6-11,16,22,24-26,30,42H,4-5,12-15,17-21H2,1-2H3,(H2,35,36,43)/t22-,24?,25?,26?,30+,33?/m1/s1 DFTSMKPUBOXVKF-UENLDKMFSA-N 50231349 1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-phenyl)-propyl]-amino}-2-hydroxy-1-methyl-propyl)-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL252610 C-C chemokine receptor type 3 Homo sapiens 421 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231349&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447142 104055080 CHEMBL252610 ZINC29039061 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408751 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)[C@@H](C)[C@H](O)c1ccccc1 InChI=1S/C23H31N7O3/c1-15(20(31)14-29(3)16(2)21(32)17-9-6-5-7-10-17)24-23(33)25-19-12-8-11-18(13-19)22-26-27-28-30(22)4/h5-13,15-16,20-21,31-32H,14H2,1-4H3,(H2,24,25,33)/t15-,16+,20+,21+/m1/s1 BVVNIEMHJMWNCD-ALGWMNEGSA-N 50231351 1-((2R,3S)-3-hydroxy-4-(((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252222 C-C chemokine receptor type 3 Homo sapiens 5.7 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231351&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447369 104055082 CHEMBL252222 ZINC29039831 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408752 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.01 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408753 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)C2CC2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-4-19-14-21(26-31-32-33-34(26)3)16-23(15-19)30-27(37)29-18(2)25(36)17-35(24-11-12-24)13-5-6-20-7-9-22(28)10-8-20/h7-10,14-16,18,24-25,36H,4-6,11-13,17H2,1-3H3,(H2,29,30,37)/t18-,25+/m1/s1 JEWWLECKWFDBAS-CJAUYULYSA-N 50231352 1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254677 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231352&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447146 104055083 CHEMBL254677 ZINC29039071 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408754 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)[C@H](C)[C@H](O)c1ccccc1 InChI=1S/C23H31N7O3/c1-15(20(31)14-29(3)16(2)21(32)17-9-6-5-7-10-17)24-23(33)25-19-12-8-11-18(13-19)22-26-27-28-30(22)4/h5-13,15-16,20-21,31-32H,14H2,1-4H3,(H2,24,25,33)/t15-,16-,20+,21+/m1/s1 BVVNIEMHJMWNCD-RFZJPIJTSA-N 50231353 1-((2R,3S)-3-hydroxy-4-(((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252221 C-C chemokine receptor type 3 Homo sapiens 577 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231353&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447366 104055084 CHEMBL252221 ZINC29039823 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408755 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C)[C@@H](C)CCc1ccc(F)cc1 InChI=1S/C27H38FN7O2/c1-6-20-14-22(26-31-32-33-34(26)5)16-24(15-20)30-27(37)29-19(4)25(36)17-35(7-2)18(3)8-9-21-10-12-23(28)13-11-21/h10-16,18-19,25,36H,6-9,17H2,1-5H3,(H2,29,30,37)/t18-,19+,25-/m0/s1 JRJPTAPFBNEIPL-CEYNDMKZSA-N 50231354 1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254095 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231354&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447381 104055085 CHEMBL254095 ZINC29039907 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408756 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)[C@@H](C)[C@@H](O)c1ccccc1 InChI=1S/C23H31N7O3/c1-15(20(31)14-29(3)16(2)21(32)17-9-6-5-7-10-17)24-23(33)25-19-12-8-11-18(13-19)22-26-27-28-30(22)4/h5-13,15-16,20-21,31-32H,14H2,1-4H3,(H2,24,25,33)/t15-,16+,20+,21-/m1/s1 BVVNIEMHJMWNCD-QMKUDKLTSA-N 50231347 1-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254503 C-C chemokine receptor type 3 Homo sapiens 22 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231347&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447361 104055078 CHEMBL254503 ZINC29039802 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408757 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.01 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408758 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)CC23CC4CC(CC(C4)C2)C3)cc(c1)-c1nnnn1C InChI=1S/C35H48FN7O2/c1-4-24-15-29(33-39-40-41-42(33)3)17-31(16-24)38-34(45)37-23(2)32(44)21-43(11-5-6-25-7-9-30(36)10-8-25)22-35-18-26-12-27(19-35)14-28(13-26)20-35/h7-10,15-17,23,26-28,32,44H,4-6,11-14,18-22H2,1-3H3,(H2,37,38,45)/t23-,26?,27?,28?,32+,35?/m1/s1 YHXDUUWKFOEDMD-AJCADDFISA-N 50231355 1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-phenyl)-propyl]-amino}-2-hydroxy-1-methyl-propyl)-3-[3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL398344 C-C chemokine receptor type 3 Homo sapiens 211 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231355&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447153 104055086 CHEMBL398344 ZINC29039087 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408759 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)C2CCCCC2)cc(c1)-c1nnnn1C InChI=1S/C30H42FN7O2/c1-4-22-17-24(29-34-35-36-37(29)3)19-26(18-22)33-30(40)32-21(2)28(39)20-38(27-10-6-5-7-11-27)16-8-9-23-12-14-25(31)15-13-23/h12-15,17-19,21,27-28,39H,4-11,16,20H2,1-3H3,(H2,32,33,40)/t21-,28+/m1/s1 QUQUATAXKUIJRN-PIKZIKFNSA-N 50231356 1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254470 C-C chemokine receptor type 3 Homo sapiens 3.2 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231356&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447149 104055087 CHEMBL254470 ZINC29039079 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408760 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(CCCc1ccc(F)cc1)C1CCCCC1 InChI=1S/C28H38FN7O2/c1-20(30-28(38)31-24-10-6-9-22(18-24)27-32-33-34-35(27)2)26(37)19-36(25-11-4-3-5-12-25)17-7-8-21-13-15-23(29)16-14-21/h6,9-10,13-16,18,20,25-26,37H,3-5,7-8,11-12,17,19H2,1-2H3,(H2,30,31,38)/t20-,26+/m1/s1 PNWLTYBLOADJOL-IBVKSMDESA-N 50231359 1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL251839 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231359&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447140 104055090 CHEMBL251839 ZINC29039057 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408761 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)CCCc1ccc(F)cc1 InChI=1S/C23H30FN7O2/c1-16(21(32)15-30(2)13-5-6-17-9-11-19(24)12-10-17)25-23(33)26-20-8-4-7-18(14-20)22-27-28-29-31(22)3/h4,7-12,14,16,21,32H,5-6,13,15H2,1-3H3,(H2,25,26,33)/t16-,21+/m1/s1 CKJOKWIJVHXLCN-IERDGZPVSA-N 50231357 1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252631 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231357&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447135 104055088 CHEMBL252631 ZINC29039047 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408763 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(CCCc1ccc(F)cc1)CC(F)(F)F InChI=1S/C24H29F4N7O2/c1-16(29-23(37)30-20-7-3-6-18(13-20)22-31-32-33-34(22)2)21(36)14-35(15-24(26,27)28)12-4-5-17-8-10-19(25)11-9-17/h3,6-11,13,16,21,36H,4-5,12,14-15H2,1-2H3,(H2,29,30,37)/t16-,21+/m1/s1 UDHGEHYYTGTWBP-IERDGZPVSA-N 50231362 1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252034 C-C chemokine receptor type 3 Homo sapiens 59 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231362&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447141 104055093 CHEMBL252034 ZINC29039059 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408764 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408765 CCCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H34FN7O2/c1-4-14-33(15-6-7-19-10-12-21(26)13-11-19)17-23(34)18(2)27-25(35)28-22-9-5-8-20(16-22)24-29-30-31-32(24)3/h5,8-13,16,18,23,34H,4,6-7,14-15,17H2,1-3H3,(H2,27,28,35)/t18-,23+/m1/s1 CLDHNRFYDLODMW-JPYJTQIMSA-N 50231360 1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL398548 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231360&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447137 104055091 CHEMBL398548 ZINC29039051 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408766 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(C)[C@@H](C)[C@@H](O)c2ccccc2)cc(c1)-c1nnnn1C InChI=1S/C25H35N7O3/c1-6-18-12-20(24-28-29-30-32(24)5)14-21(13-18)27-25(35)26-16(2)22(33)15-31(4)17(3)23(34)19-10-8-7-9-11-19/h7-14,16-17,22-23,33-34H,6,15H2,1-5H3,(H2,26,27,35)/t16-,17+,22+,23-/m1/s1 IBXWXSQRMSFMKL-YHFSLCLQSA-N 50231361 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)urea::CHEMBL251822 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231361&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25032958 104055092 CHEMBL251822 ZINC29039811 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408767 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(CCCc1ccc(F)cc1)CC1CC1 InChI=1S/C26H34FN7O2/c1-18(28-26(36)29-23-7-3-6-21(15-23)25-30-31-32-33(25)2)24(35)17-34(16-20-8-9-20)14-4-5-19-10-12-22(27)13-11-19/h3,6-7,10-13,15,18,20,24,35H,4-5,8-9,14,16-17H2,1-2H3,(H2,28,29,36)/t18-,24+/m1/s1 VIBMAXOUSNSFOR-KOSHJBKYSA-N 50231364 1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL251838 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231364&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447139 104055095 CHEMBL251838 ZINC29039055 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408768 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)CC(F)(F)F)cc(c1)-c1nnnn1C InChI=1S/C26H33F4N7O2/c1-4-18-12-20(24-33-34-35-36(24)3)14-22(13-18)32-25(39)31-17(2)23(38)15-37(16-26(28,29)30)11-5-6-19-7-9-21(27)10-8-19/h7-10,12-14,17,23,38H,4-6,11,15-16H2,1-3H3,(H2,31,32,39)/t17-,23+/m1/s1 VOVATKVSXOZNPW-HXOBKFHXSA-N 50231365 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)-3-hydroxybutan-2-yl)urea::CHEMBL254471 C-C chemokine receptor type 3 Homo sapiens 9 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231365&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447150 104055096 CHEMBL254471 ZINC29039081 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408769 CCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C InChI=1S/C26H36FN7O2/c1-5-19-14-21(25-30-31-32-33(25)4)16-23(15-19)29-26(36)28-18(3)24(35)17-34(6-2)13-7-8-20-9-11-22(27)12-10-20/h9-12,14-16,18,24,35H,5-8,13,17H2,1-4H3,(H2,28,29,36)/t18-,24+/m1/s1 ZKBWRGSSTRYGHO-KOSHJBKYSA-N 50231346 1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL428062 C-C chemokine receptor type 3 Homo sapiens 0.004 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231346&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447382 104055077 CHEMBL428062 ZINC29039917 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408770 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1 InChI=1S/C25H34FN7O3/c1-5-33(17(3)22(34)13-18-9-11-20(26)12-10-18)15-23(35)16(2)27-25(36)28-21-8-6-7-19(14-21)24-29-30-31-32(24)4/h6-12,14,16-17,22-23,34-35H,5,13,15H2,1-4H3,(H2,27,28,36)/t16-,17+,22+,23+/m1/s1 IKILZXIIPZFUMD-IFOZNXLVSA-N 50231363 1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253034 C-C chemokine receptor type 3 Homo sapiens 19 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231363&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447374 104055094 CHEMBL253034 ZINC29039862 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408771 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(CCCc1ccc(F)cc1)C1CC1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-21-7-3-6-19(15-21)24-29-30-31-32(24)2)23(34)16-33(22-12-13-22)14-4-5-18-8-10-20(26)11-9-18/h3,6-11,15,17,22-23,34H,4-5,12-14,16H2,1-2H3,(H2,27,28,35)/t17-,23+/m1/s1 LFTMTXMNLVRZGX-HXOBKFHXSA-N 50231367 1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL400378 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231367&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447138 104055098 CHEMBL400378 ZINC29039053 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408772 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.038 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408773 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN(CCCc2ccc(F)cc2)CC(F)(F)F)c1 InChI=1S/C27H33F4N7O/c1-37-25(34-35-36-37)20-8-4-9-23(16-20)32-26(39)33-24-10-3-2-7-21(24)17-38(18-27(29,30)31)15-5-6-19-11-13-22(28)14-12-19/h4,8-9,11-14,16,21,24H,2-3,5-7,10,15,17-18H2,1H3,(H2,32,33,39)/t21-,24+/m0/s1 CNFOPUXFDNSVFS-XUZZJYLKSA-N 50231369 1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(2,2,2-trifluoroethyl)amino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253211 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231369&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11226588 104055100 CHEMBL253211 ZINC29039115 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408774 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CNCCCc2ccc(F)cc2)c1 InChI=1S/C25H32FN7O/c1-33-24(30-31-32-33)19-8-4-9-22(16-19)28-25(34)29-23-10-3-2-7-20(23)17-27-15-5-6-18-11-13-21(26)14-12-18/h4,8-9,11-14,16,20,23,27H,2-3,5-7,10,15,17H2,1H3,(H2,28,29,34)/t20-,23+/m0/s1 BIHUZMHUADUJOS-NZQKXSOJSA-N 50231370 1-((1R,2S)-2-((3-(4-fluorophenyl)propylamino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253209 C-C chemokine receptor type 3 Homo sapiens 3.7 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231370&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11213457 104055101 CHEMBL253209 ZINC29039101 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408776 CN(CCCc1ccc(F)cc1)C[C@@H]1CCCC[C@H]1NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-33(16-6-7-19-12-14-22(27)15-13-19)18-21-8-3-4-11-24(21)29-26(35)28-23-10-5-9-20(17-23)25-30-31-32-34(25)2/h5,9-10,12-15,17,21,24H,3-4,6-8,11,16,18H2,1-2H3,(H2,28,29,35)/t21-,24+/m0/s1 ADGPNLCKGSWYFU-XUZZJYLKSA-N 50231368 1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(methyl)amino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253210 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231368&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11236950 104055099 CHEMBL253210 ZINC29039113 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408777 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C)[C@@H](C)[C@@H](O)Cc1ccc(F)cc1 InChI=1S/C27H38FN7O3/c1-6-19-12-21(26-31-32-33-34(26)5)15-23(13-19)30-27(38)29-17(3)25(37)16-35(7-2)18(4)24(36)14-20-8-10-22(28)11-9-20/h8-13,15,17-18,24-25,36-37H,6-7,14,16H2,1-5H3,(H2,29,30,38)/t17-,18+,24+,25+/m1/s1 JYQOPMMBCFIFTN-GXZJQHSTSA-N 50231366 1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253244 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231366&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447375 104055097 CHEMBL253244 ZINC29039870 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408778 CN(CCCc1ccc(F)cc1)C[C@@H]1CCCC[C@H]1NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-33(16-6-7-19-12-14-22(27)15-13-19)18-21-8-3-4-11-24(21)29-26(35)28-23-10-5-9-20(17-23)25-30-31-32-34(25)2/h5,9-10,12-15,17,21,24H,3-4,6-8,11,16,18H2,1-2H3,(H2,28,29,35)/t21-,24+/m0/s1 ADGPNLCKGSWYFU-XUZZJYLKSA-N 50231368 1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(methyl)amino)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253210 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231368&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11236950 104055099 CHEMBL253210 ZINC29039113 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408779 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN(C)[C@H](C)[C@@H](O)c1ccccc1 InChI=1S/C23H31N7O3/c1-15(20(31)14-29(3)16(2)21(32)17-9-6-5-7-10-17)24-23(33)25-19-12-8-11-18(13-19)22-26-27-28-30(22)4/h5-13,15-16,20-21,31-32H,14H2,1-4H3,(H2,24,25,33)/t15-,16-,20+,21-/m1/s1 BVVNIEMHJMWNCD-WWEWDKITSA-N 50231372 1-((2R,3S)-3-hydroxy-4-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)(methyl)amino)butan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL252628 C-C chemokine receptor type 3 Homo sapiens 238 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231372&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447373 104055103 CHEMBL252628 ZINC29039850 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408780 CCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C24H32FN7O2/c1-4-32(14-6-7-18-10-12-20(25)13-11-18)16-22(33)17(2)26-24(34)27-21-9-5-8-19(15-21)23-28-29-30-31(23)3/h5,8-13,15,17,22,33H,4,6-7,14,16H2,1-3H3,(H2,26,27,34)/t17-,22+/m1/s1 PEKYRUYJONXHSA-VGSWGCGISA-N 50231371 1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL251837 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231371&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447136 104055102 CHEMBL251837 ZINC29039049 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408781 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C)[C@@H](C)[C@H](O)Cc1ccc(F)cc1 InChI=1S/C27H38FN7O3/c1-6-19-12-21(26-31-32-33-34(26)5)15-23(13-19)30-27(38)29-17(3)25(37)16-35(7-2)18(4)24(36)14-20-8-10-22(28)11-9-20/h8-13,15,17-18,24-25,36-37H,6-7,14,16H2,1-5H3,(H2,29,30,38)/t17-,18+,24-,25+/m1/s1 JYQOPMMBCFIFTN-JIROWCAOSA-N 50231373 1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL400467 C-C chemokine receptor type 3 Homo sapiens 3.4 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231373&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447378 104055104 CHEMBL400467 ZINC29039892 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408782 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(C)CCCc2ccc(F)cc2)cc(c1)-c1nnnn1C InChI=1S/C25H34FN7O2/c1-5-18-13-20(24-29-30-31-33(24)4)15-22(14-18)28-25(35)27-17(2)23(34)16-32(3)12-6-7-19-8-10-21(26)11-9-19/h8-11,13-15,17,23,34H,5-7,12,16H2,1-4H3,(H2,27,28,35)/t17-,23+/m1/s1 HNZBBDVTXTVMDD-HXOBKFHXSA-N 50231376 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)-3-hydroxybutan-2-yl)urea::CHEMBL437396 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231376&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447144 104055107 CHEMBL437396 ZINC29039065 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408783 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)S(C)(=O)=O)cc(c1)-c1nnnn1C InChI=1S/C25H34FN7O4S/c1-5-18-13-20(24-29-30-31-32(24)3)15-22(14-18)28-25(35)27-17(2)23(34)16-33(38(4,36)37)12-6-7-19-8-10-21(26)11-9-19/h8-11,13-15,17,23,34H,5-7,12,16H2,1-4H3,(H2,27,28,35)/t17-,23+/m1/s1 LESCJEJUMNIEBF-HXOBKFHXSA-N 50231375 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(N-(3-(4-fluorophenyl)propyl)methan-12-ylsulfonamido)-3-hydroxybutan-2-yl)urea::CHEMBL254055 C-C chemokine receptor type 3 Homo sapiens 21.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231375&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447161 104055106 CHEMBL254055 ZINC29039107 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408784 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)C(C)=O)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O3/c1-5-19-13-21(25-30-31-32-33(25)4)15-23(14-19)29-26(37)28-17(2)24(36)16-34(18(3)35)12-6-7-20-8-10-22(27)11-9-20/h8-11,13-15,17,24,36H,5-7,12,16H2,1-4H3,(H2,28,29,37)/t17-,24+/m1/s1 KVENVCIOSVIRNJ-OSPHWJPCSA-N 50231374 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(N-(3-(4-fluorophenyl)propyl)acetamido)-3-hydroxybutan-2-yl)urea::CHEMBL401002 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231374&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447155 104055105 CHEMBL401002 ZINC29039091 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408785 CCCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cc(CC)cc(c1)-c1nnnn1C InChI=1S/C27H38FN7O2/c1-5-13-35(14-7-8-21-9-11-23(28)12-10-21)18-25(36)19(3)29-27(37)30-24-16-20(6-2)15-22(17-24)26-31-32-33-34(26)4/h9-12,15-17,19,25,36H,5-8,13-14,18H2,1-4H3,(H2,29,30,37)/t19-,25+/m1/s1 MUBGPUBCDUZPSB-CLOONOSVSA-N 50231380 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(propyl)amino)-3-hydroxybutan-2-yl)urea::CHEMBL254676 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231380&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447145 104055111 CHEMBL254676 ZINC29039069 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408786 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-4-19-13-22(26-31-32-33-34(26)3)15-24(14-19)30-27(37)29-18(2)25(36)17-35-11-5-6-21(16-35)12-20-7-9-23(28)10-8-20/h7-10,13-15,18,21,25,36H,4-6,11-12,16-17H2,1-3H3,(H2,29,30,37)/t18-,21+,25+/m1/s1 SGWACYVRKXWJNK-QLWBXOBMSA-N 50231350 1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254930 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231350&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10458976 104055081 CHEMBL254930 ZINC29039931 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408787 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)CCc1ccc(F)cc1 InChI=1S/C25H34FN7O2/c1-5-33(17(2)9-10-19-11-13-21(26)14-12-19)16-23(34)18(3)27-25(35)28-22-8-6-7-20(15-22)24-29-30-31-32(24)4/h6-8,11-15,17-18,23,34H,5,9-10,16H2,1-4H3,(H2,27,28,35)/t17-,18+,23-/m0/s1 GGPPNDUNCABTNM-IXFSTUDKSA-N 50231378 1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254093 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231378&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447380 104055109 CHEMBL254093 ZINC29039901 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408788 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)CC2CC2)cc(c1)-c1nnnn1C InChI=1S/C28H38FN7O2/c1-4-20-14-23(27-32-33-34-35(27)3)16-25(15-20)31-28(38)30-19(2)26(37)18-36(17-22-7-8-22)13-5-6-21-9-11-24(29)12-10-21/h9-12,14-16,19,22,26,37H,4-8,13,17-18H2,1-3H3,(H2,30,31,38)/t19-,26+/m1/s1 JBSFMYIPFYTPEY-BCHFMIIMSA-N 50231377 1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254881 C-C chemokine receptor type 3 Homo sapiens 0.005 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231377&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447147 104055108 CHEMBL254881 ZINC29039076 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408789 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CNCCCc2ccc(F)cc2)cc(c1)-c1nnnn1C InChI=1S/C24H32FN7O2/c1-4-17-12-19(23-29-30-31-32(23)3)14-21(13-17)28-24(34)27-16(2)22(33)15-26-11-5-6-18-7-9-20(25)10-8-18/h7-10,12-14,16,22,26,33H,4-6,11,15H2,1-3H3,(H2,27,28,34)/t16-,22+/m1/s1 UUGSRAAISBMNHE-ZHRRBRCNSA-N 50231379 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-(3-(4-fluorophenyl)propylamino)-3-hydroxybutan-2-yl)urea::CHEMBL252035 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231379&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447143 104055110 CHEMBL252035 ZINC29039063 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408790 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(C)CCCc2ccc(F)cc2)cc(c1)-c1nnnn1C InChI=1S/C25H34FN7O2/c1-5-18-13-20(24-29-30-31-33(24)4)15-22(14-18)28-25(35)27-17(2)23(34)16-32(3)12-6-7-19-8-10-21(26)11-9-19/h8-11,13-15,17,23,34H,5-7,12,16H2,1-4H3,(H2,27,28,35)/t17-,23+/m1/s1 HNZBBDVTXTVMDD-HXOBKFHXSA-N 50231376 1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)-3-hydroxybutan-2-yl)urea::CHEMBL437396 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231376&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447144 104055107 CHEMBL437396 ZINC29039065 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408791 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408792 CCc1cc(NC(=O)N[C@H](C)[C@@H](O)CN(CCCc2ccc(F)cc2)CC2CC2)cc(c1)-c1nnnn1C InChI=1S/C28H38FN7O2/c1-4-20-14-23(27-32-33-34-35(27)3)16-25(15-20)31-28(38)30-19(2)26(37)18-36(17-22-7-8-22)13-5-6-21-9-11-24(29)12-10-21/h9-12,14-16,19,22,26,37H,4-8,13,17-18H2,1-3H3,(H2,30,31,38)/t19-,26+/m1/s1 JBSFMYIPFYTPEY-BCHFMIIMSA-N 50231377 1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluorophenyl)propyl)amino)-3-hydroxybutan-2-yl)-3-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL254881 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231377&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447147 104055108 CHEMBL254881 ZINC29039076 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50408793 CCN(C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](C)[C@H](O)Cc1ccc(F)cc1 InChI=1S/C25H34FN7O3/c1-5-33(17(3)22(34)13-18-9-11-20(26)12-10-18)15-23(35)16(2)27-25(36)28-21-8-6-7-19(14-21)24-29-30-31-32(24)4/h6-12,14,16-17,22-23,34-35H,5,13,15H2,1-4H3,(H2,27,28,36)/t16-,17+,22-,23+/m1/s1 IKILZXIIPZFUMD-RZRCNZQPSA-N 50231381 1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-hydroxybutan-2-yl)amino)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL253666 C-C chemokine receptor type 3 Homo sapiens 88 ChEMBL 10.1016/j.bmcl.2007.11.087 10.7270/Q2FF3S4K 18160284 Gardner, DS; Santella, JB; Tebben, AJ; Batt, DG; Ko, SS; Traeger, SC; Welch, PK; Wadman, EA; Davies, P; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231381&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44447377 104055112 CHEMBL253666 ZINC29039888 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440237 CN1C[C@@H](NC(=O)Nc2cccc(c2)-c2nnnn2C)[C@H](CN(CCCc2ccc(F)cc2)C2CC2)OC1=O InChI=1S/C27H33FN8O3/c1-34-16-23(30-26(37)29-21-7-3-6-19(15-21)25-31-32-33-35(25)2)24(39-27(34)38)17-36(22-12-13-22)14-4-5-18-8-10-20(28)11-9-18/h3,6-11,15,22-24H,4-5,12-14,16-17H2,1-2H3,(H2,29,30,37)/t23-,24+/m1/s1 QPLIYSHBLNDLCU-RPWUZVMVSA-N 50255038 1-((5R,6S)-6-((cyclopropyl(3-(4-fluorophenyl)propyl)amino)methyl)-3-methyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL465942 C-C chemokine receptor type 3 Homo sapiens 2.1 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255038&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570581 104107097 CHEMBL465942 ZINC44405206 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440238 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440239 CN1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@@H](C1)NC(=O)Nc1nc(C)c(s1)C(C)=O InChI=1S/C26H36FN5O2S/c1-17-24(18(2)33)35-26(28-17)30-25(34)29-23-16-31(3)12-10-21(23)15-32-11-4-5-20(14-32)13-19-6-8-22(27)9-7-19/h6-9,20-21,23H,4-5,10-16H2,1-3H3,(H2,28,29,30,34)/t20-,21-,23+/m0/s1 HAOJBCWTKNVFJG-QNWVGRARSA-N 50209984 1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-3-yl)-3-(5-acetyl-4-methylthiazol-2-yl)urea::1-(5-acetyl-4-methylthiazol-2-yl)-3-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-1-methylpiperidin-3-yl)urea::CHEMBL410959 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209984&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44445901 104086630 CHEMBL410959 ZINC28975463 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440240 CN1CC(C)(NC(=O)Nc2nc(C)c(s2)C(C)=O)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C26H34FN5O4S/c1-16-22(17(2)33)37-24(28-16)29-23(34)30-26(3)15-31(4)25(35)36-21(26)14-32-11-5-6-19(13-32)12-18-7-9-20(27)10-8-18/h7-10,19,21H,5-6,11-15H2,1-4H3,(H2,28,29,30,34)/t19-,21?,26?/m0/s1 ZAGLIRVCRPDDPG-SFGGNAAOSA-N 50255070 1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL465291 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255070&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570617 104107123 CHEMBL465291 ZINC40877406 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440241 CCN(CCCc1ccc(F)cc1)CC1OC(=O)N(C)CC1(C)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C27H35FN8O3/c1-5-36(15-7-8-19-11-13-21(28)14-12-19)17-23-27(2,18-34(3)26(38)39-23)30-25(37)29-22-10-6-9-20(16-22)24-31-32-33-35(24)4/h6,9-14,16,23H,5,7-8,15,17-18H2,1-4H3,(H2,29,30,37) JPDQWWXKNYFGDS-UHFFFAOYSA-N 50254448 1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-(6-((ethyl(3-(4-fluorophenyl)propyl)amino)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL461445 C-C chemokine receptor type 3 Homo sapiens 0.47 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593547 104106662 CHEMBL461445 ZINC44387151 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440242 CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1 PUMZOGIVDCNTEI-ZGIGLSJSSA-N 50255042 1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465272 C-C chemokine receptor type 3 Homo sapiens 0.37 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255042&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593553 104107101 CHEMBL465272 ZINC40395691 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440243 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440244 CN1C[C@@H](NC(=O)Nc2cccc(c2)-c2nnnn2C)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C27H33FN8O3/c1-34-16-23(30-26(37)29-22-7-3-6-20(14-22)25-31-32-33-35(25)2)24(39-27(34)38)17-36-12-4-5-19(15-36)13-18-8-10-21(28)11-9-18/h3,6-11,14,19,23-24H,4-5,12-13,15-17H2,1-2H3,(H2,29,30,37)/t19-,23+,24-/m0/s1 RHPFRSVVYGFARI-IEXUWNMDSA-N 50255006 1-((5R,6S)-6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3-methyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL464902 C-C chemokine receptor type 3 Homo sapiens 0.23 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255006&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570537 104107075 CHEMBL464902 ZINC44404296 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440245 CCN(CCCc1ccc(F)cc1)CC1OC(=O)N(C)CC1(C)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C27H35FN8O3/c1-5-36(15-7-8-19-11-13-21(28)14-12-19)17-23-27(2,18-34(3)26(38)39-23)30-25(37)29-22-10-6-9-20(16-22)24-31-32-33-35(24)4/h6,9-14,16,23H,5,7-8,15,17-18H2,1-4H3,(H2,29,30,37) JPDQWWXKNYFGDS-UHFFFAOYSA-N 50254448 1-(6-((ethyl(3-(4-fluorophenyl) propyl)amino)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-(6-((ethyl(3-(4-fluorophenyl)propyl)amino)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL461445 C-C chemokine receptor type 3 Homo sapiens 0.470 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593547 104106662 CHEMBL461445 ZINC44387151 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440246 CN1CC(C)(NC(=O)Nc2cccc(c2)-c2nnnn2C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C28H35FN8O3/c1-28(31-26(38)30-23-8-4-7-21(15-23)25-32-33-34-36(25)3)18-35(2)27(39)40-24(28)17-37-13-5-6-20(16-37)14-19-9-11-22(29)12-10-19/h4,7-12,15,20,24H,5-6,13-14,16-18H2,1-3H3,(H2,30,31,38)/t20-,24?,28?/m0/s1 OTSUKARJPJAFRM-UEHGGBRMSA-N 50255040 1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL505914::CHEMBL518571 C-C chemokine receptor type 3 Homo sapiens 0.15 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255040&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570583 104107099 CHEMBL518571CHEMBL505914 ZINC42834010 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440247 CN1CC(C)(NC(=O)Nc2cccc(c2)-c2nnnn2C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C28H35FN8O3/c1-28(31-26(38)30-23-8-4-7-21(15-23)25-32-33-34-36(25)3)18-35(2)27(39)40-24(28)17-37-13-5-6-20(16-37)14-19-9-11-22(29)12-10-19/h4,7-12,15,20,24H,5-6,13-14,16-18H2,1-3H3,(H2,30,31,38)/t20-,24?,28?/m0/s1 OTSUKARJPJAFRM-UEHGGBRMSA-N 50255040 1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL505914::CHEMBL518571 C-C chemokine receptor type 3 Homo sapiens 0.12 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255040&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570583 104107099 CHEMBL518571CHEMBL505914 ZINC42834010 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440248 CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1 PUMZOGIVDCNTEI-ZGIGLSJSSA-N 50255042 1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465272 C-C chemokine receptor type 3 Homo sapiens 0.370 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255042&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593553 104107101 CHEMBL465272 ZINC40395691 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440249 CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C27H38FN5O3S/c1-26(2,3)21-16-37-24(29-21)30-23(34)31-27(4)17-32(5)25(35)36-22(27)15-33-12-6-7-19(14-33)13-18-8-10-20(28)11-9-18/h8-11,16,19,22H,6-7,12-15,17H2,1-5H3,(H2,29,30,31,34)/t19-,22?,27?/m0/s1 UKCCRJLNYAYHBT-JIUXCQJLSA-N 50254447 1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL468695 C-C chemokine receptor type 3 Homo sapiens 5.5 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593546 104106661 CHEMBL468695 ZINC40891751 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440250 CCCN(CCCc1ccc(F)cc1)C[C@@H]1OC(=O)N(C)C[C@H]1NC(=O)Nc1nc(C)cs1 InChI=1S/C23H32FN5O3S/c1-4-11-29(12-5-6-17-7-9-18(24)10-8-17)14-20-19(13-28(3)23(31)32-20)26-21(30)27-22-25-16(2)15-33-22/h7-10,15,19-20H,4-6,11-14H2,1-3H3,(H2,25,26,27,30)/t19-,20+/m1/s1 IETOCDITJQQYHS-UXHICEINSA-N 50255039 1-((5R,6S)-6-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-3-methyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465943 C-C chemokine receptor type 3 Homo sapiens 9.2 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255039&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570582 104107098 CHEMBL465943 ZINC40395141 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440251 CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1 PUMZOGIVDCNTEI-ZGIGLSJSSA-N 50255042 1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465272 C-C chemokine receptor type 3 Homo sapiens 5.40 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255042&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593553 104107101 CHEMBL465272 ZINC40395691 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440253 CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O InChI=1S/C27H38FN5O3S/c1-26(2,3)21-16-37-24(29-21)30-23(34)31-27(4)17-32(5)25(35)36-22(27)15-33-12-6-7-19(14-33)13-18-8-10-20(28)11-9-18/h8-11,16,19,22H,6-7,12-15,17H2,1-5H3,(H2,29,30,31,34)/t19-,22?,27?/m0/s1 UKCCRJLNYAYHBT-JIUXCQJLSA-N 50254447 1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL468695 C-C chemokine receptor type 3 Homo sapiens 5.50 ChEMBL 10.1016/j.bmcl.2008.11.002 10.7270/Q2MG7PCW 19010676 Dhar, TG; Yang, G; Davies, P; Malley, MF; Gougoutas, JZ; Wu, DR; Barrish, JC; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254447&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593546 104106661 CHEMBL468695 ZINC40891751 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50440400 CCCCC1C(=O)N(C[C@H]2CC[C@@H](CC2)OCC)CCC11CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C InChI=1S/C35H57N5O3/c1-6-8-9-30-32(41)39(24-28-10-12-29(13-11-28)43-7-2)21-16-35(30)17-22-40(23-18-35)34(5)14-19-38(20-15-34)33(42)31-26(3)36-25-37-27(31)4/h25,28-30H,6-24H2,1-5H3/t28-,29-,30? QOJYCEFGDGHBCC-PXGVVOSNSA-N 50254750 1-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-(((1r,4r)-4-ethoxycyclohexyl)methyl)-3,9-diazaspiro[5.5]undecan-2-one::CHEMBL449621 C-C chemokine receptor type 3 Homo sapiens >50000 ChEMBL 10.1016/j.bmcl.2008.10.115 10.7270/Q2FQ9WGB 19014885 Yang, H; Lin, XF; Padilla, F; Gabriel, SD; Heilek, G; Ji, C; Sankuratri, S; deRosier, A; Berry, P; Rotstein, DM Roche Palo Alto LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254750&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25230828 104106913 CHEMBL449621 ZINC42834646 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50447489 CSc1ccc(cc1)C(=O)NC1CCNCC1NC(=O)CNC(=O)c1cc(ccc1N)C(F)(F)F InChI=1S/C23H26F3N5O3S/c1-35-15-5-2-13(3-6-15)21(33)31-18-8-9-28-11-19(18)30-20(32)12-29-22(34)16-10-14(23(24,25)26)4-7-17(16)27/h2-7,10,18-19,28H,8-9,11-12,27H2,1H3,(H,29,34)(H,30,32)(H,31,33) FUTBXMDGBHHNLB-UHFFFAOYSA-N 50255735 (+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)piperidin-3-ylamino)-2-oxoethyl)-5-(trifluoromethyl)benzamide::CHEMBL481790 C-C chemokine receptor type 3 Homo sapiens 19.7 ChEMBL 10.1016/j.bmcl.2008.12.062 10.7270/Q2QF8SR1 19131247 Cherney, RJ; Brogan, JB; Mo, R; Lo, YC; Yang, G; Miller, PB; Scherle, PA; Molino, BF; Carter, PH; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255735&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22143196 104107477 CHEMBL481790 ZINC40411602 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50447505 CSc1ccc(cc1)C(=O)NC1CCC(CC1NC(=O)CNC(=O)c1cc(ccc1N)C(F)(F)F)NC(C)C InChI=1S/C27H34F3N5O3S/c1-15(2)33-18-7-11-22(35-25(37)16-4-8-19(39-3)9-5-16)23(13-18)34-24(36)14-32-26(38)20-12-17(27(28,29)30)6-10-21(20)31/h4-6,8-10,12,15,18,22-23,33H,7,11,13-14,31H2,1-3H3,(H,32,38)(H,34,36)(H,35,37) HTGCOGKGWKXISK-UHFFFAOYSA-N 50255171 (+/-)-2-amino-N-(2-(5-(isopropylamino)-2-(4-(methylthio)benzamido)cyclohexylamino)-2-oxoethyl)-5-(trifluoromethyl)benzamide::CHEMBL516224 C-C chemokine receptor type 3 Homo sapiens 27.2 ChEMBL 10.1016/j.bmcl.2008.12.062 10.7270/Q2QF8SR1 19131247 Cherney, RJ; Brogan, JB; Mo, R; Lo, YC; Yang, G; Miller, PB; Scherle, PA; Molino, BF; Carter, PH; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255171&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44570714 104107181 CHEMBL516224 ZINC42876320 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50447507 CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1 InChI=1S/C32H33F3N4O5S/c1-45-25-13-10-21(11-14-25)30(42)39-27-17-24(37-31(43)44-19-20-6-3-2-4-7-20)12-15-26(27)38-28(40)18-36-29(41)22-8-5-9-23(16-22)32(33,34)35/h2-11,13-14,16,24,26-27H,12,15,17-19H2,1H3,(H,36,41)(H,37,43)(H,38,40)(H,39,42) LAPGFBUSBADRJT-UHFFFAOYSA-N 50255219 (+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::(+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::CHEMBL505722 C-C chemokine receptor type 3 Homo sapiens 7 ChEMBL 10.1016/j.bmcl.2008.12.062 10.7270/Q2QF8SR1 19131247 Cherney, RJ; Brogan, JB; Mo, R; Lo, YC; Yang, G; Miller, PB; Scherle, PA; Molino, BF; Carter, PH; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255219&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44593555 104107219 CHEMBL505722 ZINC49898171 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515432 Oc1ccccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H30FN3O3/c30-24-8-7-22-15-21(5-6-23(22)17-24)18-32-12-11-25(19-32)31-28(35)16-20-9-13-33(14-10-20)29(36)26-3-1-2-4-27(26)34/h1-8,15-17,25,34H,9-14,18-19H2,(H,31,35)/t25-/m1/s1 TVBOHVNCFNQWSW-RUZDIDTESA-N 50297171 CHEMBL551735::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 8.4 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297171&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44512617 104138702 CHEMBL551735 ZINC43024685 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515434 Cc1ccc(C(=O)N2CCC(CC2)=CC(=O)N[C@@H]2CCN(Cc3ccc4cc(F)ccc4c3)C2)c(O)c1 InChI=1S/C30H32FN3O3/c1-20-2-7-27(28(35)14-20)30(37)34-12-8-21(9-13-34)16-29(36)32-26-10-11-33(19-26)18-22-3-4-24-17-25(31)6-5-23(24)15-22/h2-7,14-17,26,35H,8-13,18-19H2,1H3,(H,32,36)/t26-/m1/s1 YRRCANFVAJKRKS-AREMUKBSSA-N 50297172 CHEMBL560275::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-4-methylbenzoyl)piperidin-4-ylidene]-acetamide C-C chemokine receptor type 3 Homo sapiens 0.980000 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297172&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45267588 104138703 CHEMBL560275 ZINC43119220 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515435 Oc1cc(Cl)ccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H29ClFN3O3/c30-23-4-6-26(27(35)16-23)29(37)34-11-7-19(8-12-34)14-28(36)32-25-9-10-33(18-25)17-20-1-2-22-15-24(31)5-3-21(22)13-20/h1-6,13-16,25,35H,7-12,17-18H2,(H,32,36)/t25-/m1/s1 ADGYFBWBQIOUQC-RUZDIDTESA-N 50297173 2-[1-(4-Chloro-2-hydroxybenzoyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL564022 C-C chemokine receptor type 3 Homo sapiens 7.5 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297173&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45269320 104138704 CHEMBL564022 ZINC43074620 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515436 Oc1cc(F)ccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H29F2N3O3/c30-23-4-3-21-13-20(1-2-22(21)15-23)17-33-10-9-25(18-33)32-28(36)14-19-7-11-34(12-8-19)29(37)26-6-5-24(31)16-27(26)35/h1-6,13-16,25,35H,7-12,17-18H2,(H,32,36)/t25-/m1/s1 CNRGFQVKYSOJGD-RUZDIDTESA-N 50297174 2-[1-(4-Fluoro-2-hydroxybenzoyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL561740 C-C chemokine receptor type 3 Homo sapiens 6 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297174&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45268467 104138705 CHEMBL561740 ZINC43120857 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515437 COc1cccc(O)c1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C30H32FN3O4/c1-38-27-4-2-3-26(35)29(27)30(37)34-13-9-20(10-14-34)16-28(36)32-25-11-12-33(19-25)18-21-5-6-23-17-24(31)8-7-22(23)15-21/h2-8,15-17,25,35H,9-14,18-19H2,1H3,(H,32,36)/t25-/m1/s1 POLVMCDWJGUXGJ-RUZDIDTESA-N 50297175 CHEMBL562922::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-6-methoxybenzoyl)piperidin-4-ylidene]-acetamide C-C chemokine receptor type 3 Homo sapiens 45 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297175&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273639 104138706 CHEMBL562922 ZINC43062461 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515438 COc1ccc(O)c(c1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C30H32FN3O4/c1-38-26-6-7-28(35)27(17-26)30(37)34-12-8-20(9-13-34)15-29(36)32-25-10-11-33(19-25)18-21-2-3-23-16-24(31)5-4-22(23)14-21/h2-7,14-17,25,35H,8-13,18-19H2,1H3,(H,32,36)/t25-/m1/s1 ZNFBEAQCHXSVEN-RUZDIDTESA-N 50297176 CHEMBL562574::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-5-methoxybenzoyl)piperidin-4-ylidene]-acetamide C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297176&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271843 104138707 CHEMBL562574 ZINC43065535 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515439 COc1ccc(C(=O)N2CCC(CC2)=CC(=O)N[C@@H]2CCN(Cc3ccc4cc(F)ccc4c3)C2)c(O)c1 InChI=1S/C30H32FN3O4/c1-38-26-6-7-27(28(35)17-26)30(37)34-12-8-20(9-13-34)15-29(36)32-25-10-11-33(19-25)18-21-2-3-23-16-24(31)5-4-22(23)14-21/h2-7,14-17,25,35H,8-13,18-19H2,1H3,(H,32,36)/t25-/m1/s1 HYNMLEFKVAYGCJ-RUZDIDTESA-N 50297177 CHEMBL561535::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-4-methoxybenzoyl)piperidin-4-ylidene]-acetamide C-C chemokine receptor type 3 Homo sapiens 3.3 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297177&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45268462 104138708 CHEMBL561535 ZINC43066982 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515440 COc1cccc(C(=O)N2CCC(CC2)=CC(=O)N[C@@H]2CCN(Cc3ccc4cc(F)ccc4c3)C2)c1O InChI=1S/C30H32FN3O4/c1-38-27-4-2-3-26(29(27)36)30(37)34-13-9-20(10-14-34)16-28(35)32-25-11-12-33(19-25)18-21-5-6-23-17-24(31)8-7-22(23)15-21/h2-8,15-17,25,36H,9-14,18-19H2,1H3,(H,32,35)/t25-/m1/s1 DKZWTUQOWFGKME-RUZDIDTESA-N 50297178 CHEMBL565165::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-3-methoxybenzoyl)piperidin-4-ylidene]-acetamide C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297178&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45268458 104138709 CHEMBL565165 ZINC43014790 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515441 Oc1ccc(cc1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H30FN3O3/c30-25-6-3-23-15-21(1-2-24(23)17-25)18-32-12-11-26(19-32)31-28(35)16-20-9-13-33(14-10-20)29(36)22-4-7-27(34)8-5-22/h1-8,15-17,26,34H,9-14,18-19H2,(H,31,35)/t26-/m1/s1 AHNCPMUENNAKMN-AREMUKBSSA-N 50297179 CHEMBL562923::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(4-hydroxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 5.1 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297179&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273698 104138710 CHEMBL562923 ZINC43016219 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515442 Oc1cccc(c1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H30FN3O3/c30-25-7-6-22-14-21(4-5-23(22)16-25)18-32-11-10-26(19-32)31-28(35)15-20-8-12-33(13-9-20)29(36)24-2-1-3-27(34)17-24/h1-7,14-17,26,34H,8-13,18-19H2,(H,31,35)/t26-/m1/s1 YOHNUIZUGOQKIN-AREMUKBSSA-N 50297180 CHEMBL556916::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(3-hydroxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297180&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273632 104138711 CHEMBL556916 ZINC43009252 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515443 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCN(CC3)C(=O)c3ccc4OCOc4c3)ccc2c1 InChI=1S/C30H30FN3O4/c31-25-5-3-22-13-21(1-2-23(22)15-25)17-33-10-9-26(18-33)32-29(35)14-20-7-11-34(12-8-20)30(36)24-4-6-27-28(16-24)38-19-37-27/h1-6,13-16,26H,7-12,17-19H2,(H,32,35)/t26-/m1/s1 CEGOGJRTCSTEOH-AREMUKBSSA-N 50297181 2-[1-(1,3-Benzodioxol-5-ylcarbonyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL551739 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297181&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271892 104138712 CHEMBL551739 ZINC43025609 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515444 COc1ccc(cc1OC)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C31H34FN3O4/c1-38-28-8-6-25(18-29(28)39-2)31(37)35-13-9-21(10-14-35)16-30(36)33-27-11-12-34(20-27)19-22-3-4-24-17-26(32)7-5-23(24)15-22/h3-8,15-18,27H,9-14,19-20H2,1-2H3,(H,33,36)/t27-/m1/s1 YKGYCRCKDMNYMC-HHHXNRCGSA-N 50297182 2-[1-(3,4-Dimethoxybenzoyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL560995 C-C chemokine receptor type 3 Homo sapiens 3.6 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297182&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45269302 104138713 CHEMBL560995 ZINC43120455 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515445 COc1ccc(cc1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C30H32FN3O3/c1-37-28-8-5-23(6-9-28)30(36)34-14-10-21(11-15-34)17-29(35)32-27-12-13-33(20-27)19-22-2-3-25-18-26(31)7-4-24(25)16-22/h2-9,16-18,27H,10-15,19-20H2,1H3,(H,32,35)/t27-/m1/s1 NBEBRANGMLOBMY-HHHXNRCGSA-N 50297183 CHEMBL551738::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(4-methoxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297183&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271891 104138714 CHEMBL551738 ZINC43025592 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515446 COc1cccc(c1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C30H32FN3O3/c1-37-28-4-2-3-25(18-28)30(36)34-13-9-21(10-14-34)16-29(35)32-27-11-12-33(20-27)19-22-5-6-24-17-26(31)8-7-23(24)15-22/h2-8,15-18,27H,9-14,19-20H2,1H3,(H,32,35)/t27-/m1/s1 NBOPVSYZBBKACL-HHHXNRCGSA-N 50297184 CHEMBL557118::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(3-methoxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 5.8 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297184&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273689 104138715 CHEMBL557118 ZINC43060041 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515447 COc1ccccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C30H32FN3O3/c1-37-28-5-3-2-4-27(28)30(36)34-14-10-21(11-15-34)17-29(35)32-26-12-13-33(20-26)19-22-6-7-24-18-25(31)9-8-23(24)16-22/h2-9,16-18,26H,10-15,19-20H2,1H3,(H,32,35)/t26-/m1/s1 IJNQDTPSBBJNGA-AREMUKBSSA-N 50297185 CHEMBL556227::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-methoxybenzoyl)piperidin-4-ylidene]acetamide C-C chemokine receptor type 3 Homo sapiens 5.1 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297185&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45272697 104138716 CHEMBL556227 ZINC43024079 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515448 Fc1ccc(cc1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H29F2N3O2/c30-25-6-3-22(4-7-25)29(36)34-13-9-20(10-14-34)16-28(35)32-27-11-12-33(19-27)18-21-1-2-24-17-26(31)8-5-23(24)15-21/h1-8,15-17,27H,9-14,18-19H2,(H,32,35)/t27-/m1/s1 LDJORPVZQXTWCA-HHHXNRCGSA-N 50297186 2-[1-(4-Fluorobenzoyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL550464 C-C chemokine receptor type 3 Homo sapiens 22 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297186&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45270980 104138717 CHEMBL550464 ZINC43017063 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515449 Fc1cccc(c1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C29H29F2N3O2/c30-25-3-1-2-24(17-25)29(36)34-12-8-20(9-13-34)15-28(35)32-27-10-11-33(19-27)18-21-4-5-23-16-26(31)7-6-22(23)14-21/h1-7,14-17,27H,8-13,18-19H2,(H,32,35)/t27-/m1/s1 GEODVCGLPKOYSN-HHHXNRCGSA-N 50297187 (R)-2-(1-(3-fluorobenzoyl)piperidin-4-ylidene)-N-(1-((6-fluoronaphthalen-2-yl)methyl)pyrrolidin-3-yl)acetamide::CHEMBL563536 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297187&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45270978 104138718 CHEMBL563536 ZINC43018041 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515450 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCN(CC3)C(=O)c3ccccc3F)ccc2c1 InChI=1S/C29H29F2N3O2/c30-24-8-7-22-15-21(5-6-23(22)17-24)18-33-12-11-25(19-33)32-28(35)16-20-9-13-34(14-10-20)29(36)26-3-1-2-4-27(26)31/h1-8,15-17,25H,9-14,18-19H2,(H,32,35)/t25-/m1/s1 MKJUKAUNROWEHZ-RUZDIDTESA-N 50297188 2-[1-(2-Fluorobenzoyl)piperidin-4-ylidene]-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL556500 C-C chemokine receptor type 3 Homo sapiens 4.8 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297188&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273624 104138719 CHEMBL556500 ZINC43063226 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515451 CC(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H28FN3O2/c1-17(29)28-10-6-18(7-11-28)13-24(30)26-23-8-9-27(16-23)15-19-2-3-21-14-22(25)5-4-20(21)12-19/h2-5,12-14,23H,6-11,15-16H2,1H3,(H,26,30)/t23-/m1/s1 VSVSVIPQECPZMU-HSZRJFAPSA-N 50297189 2-(1-Acetylpiperidin-4-ylidene)-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL550255 C-C chemokine receptor type 3 Homo sapiens 160 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297189&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45270977 104138720 CHEMBL550255 ZINC43011380 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515452 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCN(CC3)C(=O)c3ccccc3)ccc2c1 InChI=1S/C29H30FN3O2/c30-26-9-8-24-16-22(6-7-25(24)18-26)19-32-13-12-27(20-32)31-28(34)17-21-10-14-33(15-11-21)29(35)23-4-2-1-3-5-23/h1-9,16-18,27H,10-15,19-20H2,(H,31,34)/t27-/m1/s1 UVLJMOWGODVTHE-HHHXNRCGSA-N 50297190 2-(1-Benzoylpiperidin-4-ylidene)-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acetamide::CHEMBL563189 C-C chemokine receptor type 3 Homo sapiens 4.4 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297190&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9847583 104138721 CHEMBL563189 ZINC43080508 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515453 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)\C=C\C3CCN(CC3)C(=O)c3ccccc3)ccc2c1 InChI=1S/C30H32FN3O2/c31-27-10-9-25-18-23(6-8-26(25)19-27)20-33-15-14-28(21-33)32-29(35)11-7-22-12-16-34(17-13-22)30(36)24-4-2-1-3-5-24/h1-11,18-19,22,28H,12-17,20-21H2,(H,32,35)/b11-7+/t28-/m1/s1 GSABPLXEDGVPNJ-IJMNMRELSA-N 50297191 (2E)-3-(1-Benzoylpiperidin-4-yl)-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}acrylamide::CHEMBL563303 C-C chemokine receptor type 3 Homo sapiens 900 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297191&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273619 104138722 CHEMBL563303 ZINC43122228 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515454 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCC(CC3)Oc3ccccc3)ccc2c1 InChI=1S/C29H31FN2O2/c30-25-11-10-23-16-22(6-9-24(23)18-25)19-32-15-14-26(20-32)31-29(33)17-21-7-12-28(13-8-21)34-27-4-2-1-3-5-27/h1-6,9-11,16-18,26,28H,7-8,12-15,19-20H2,(H,31,33)/b21-17-/t26-,28?/m1/s1 BLIXSIRUUZYDMW-ADPJQGBTSA-N 50297192 CHEMBL560135::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-(4-phenoxycyclohexylidene)acetamide C-C chemokine receptor type 3 Homo sapiens 210 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297192&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45268444 104138723 CHEMBL560135 ZINC43074175 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515455 Fc1ccc2cc(CN3CCC(CC3)NC(=O)NS(=O)(=O)c3ccccc3)ccc2c1 InChI=1S/C23H24FN3O3S/c24-20-9-8-18-14-17(6-7-19(18)15-20)16-27-12-10-21(11-13-27)25-23(28)26-31(29,30)22-4-2-1-3-5-22/h1-9,14-15,21H,10-13,16H2,(H2,25,26,28) SFPGIRFFPMPQLC-UHFFFAOYSA-N 50297193 CHEMBL551205::N-({1-[(6-Fluoro-2-naphthyl)methyl]piperidin-4-yl}carbamoyl)benzenesulfonamide C-C chemokine receptor type 3 Homo sapiens 2000 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297193&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45270135 104138724 CHEMBL551205 ZINC43120257 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515456 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)NS(=O)(=O)c3ccccc3)ccc2c1 InChI=1S/C22H22FN3O3S/c23-19-9-8-17-12-16(6-7-18(17)13-19)14-26-11-10-20(15-26)24-22(27)25-30(28,29)21-4-2-1-3-5-21/h1-9,12-13,20H,10-11,14-15H2,(H2,24,25,27)/t20-/m1/s1 MCPUMUXGLDOLFP-HXUWFJFHSA-N 50297194 CHEMBL563019::N-({(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}carbamoyl)benzenesulfonamide C-C chemokine receptor type 3 Homo sapiens 250 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297194&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45269291 104138725 CHEMBL563019 ZINC43014045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515457 Fc1ccc2cc(CN3CCC(CC3)NC(=O)\C=C\c3ccccc3)ccc2c1 InChI=1S/C25H25FN2O/c26-23-10-9-21-16-20(6-8-22(21)17-23)18-28-14-12-24(13-15-28)27-25(29)11-7-19-4-2-1-3-5-19/h1-11,16-17,24H,12-15,18H2,(H,27,29)/b11-7+ CBQSNFCXAYXVQO-YRNVUSSQSA-N 50225356 (2E)-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}-3-phenylacrylamide::CHEMBL408486::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)cinnamamide C-C chemokine receptor type 3 Homo sapiens 9700 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225356&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452198 104096675 CHEMBL408486 ZINC29123377 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515458 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)\C=C\c3ccccc3)ccc2c1 InChI=1S/C24H23FN2O/c25-22-10-9-20-14-19(6-8-21(20)15-22)16-27-13-12-23(17-27)26-24(28)11-7-18-4-2-1-3-5-18/h1-11,14-15,23H,12-13,16-17H2,(H,26,28)/b11-7+/t23-/m1/s1 DXMGONNADLQMGE-GULCCPCXSA-N 50297195 (2E)-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-3-phenylacrylamide::CHEMBL560198 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297195&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45269392 104138726 CHEMBL560198 ZINC43076568 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515459 Fc1ccc2cc(CN3CCC(CC3)NC(=O)Cc3ccccc3)ccc2c1 InChI=1S/C24H25FN2O/c25-22-9-8-20-14-19(6-7-21(20)16-22)17-27-12-10-23(11-13-27)26-24(28)15-18-4-2-1-3-5-18/h1-9,14,16,23H,10-13,15,17H2,(H,26,28) UXWIDVSISZLIAE-UHFFFAOYSA-N 50297196 CHEMBL557936::N-{1-[(6-Fluoro-2-naphthyl)methyl]piperidin-4-yl}-2-phenylacetamide C-C chemokine receptor type 3 Homo sapiens 300 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297196&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45273705 104138727 CHEMBL557936 ZINC43024396 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515460 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)Cc3ccccc3)ccc2c1 InChI=1S/C23H23FN2O/c24-21-9-8-19-12-18(6-7-20(19)14-21)15-26-11-10-22(16-26)25-23(27)13-17-4-2-1-3-5-17/h1-9,12,14,22H,10-11,13,15-16H2,(H,25,27)/t22-/m1/s1 QZWYQJYWTHDPMU-JOCHJYFZSA-N 50297197 CHEMBL549514::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-phenylacetamide C-C chemokine receptor type 3 Homo sapiens 170 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297197&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271911 104138728 CHEMBL549514 ZINC43018253 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515461 Fc1ccc(cc1)C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C23H22F2N2O/c24-20-6-3-17(4-7-20)23(28)26-22-9-11-27(12-10-22)15-16-1-2-19-14-21(25)8-5-18(19)13-16/h1-8,13-14,22H,9-12,15H2,(H,26,28) GVYDSNDGNRGVMY-UHFFFAOYSA-N 50225353 4-fluoro-N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)benzamide::4-fluoro-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide::CHEMBL408407 C-C chemokine receptor type 3 Homo sapiens 640 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225353&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452086 104096674 CHEMBL408407 ZINC29123235 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515462 Fc1ccc(cc1)C(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C22H20F2N2O/c23-19-6-3-16(4-7-19)22(27)25-21-9-10-26(14-21)13-15-1-2-18-12-20(24)8-5-17(18)11-15/h1-8,11-12,21H,9-10,13-14H2,(H,25,27)/t21-/m1/s1 GBEZOOMNAQDDIS-OAQYLSRUSA-N 50297198 4-Fluoro-N-{(3R)-1-[(6-fluoro-2-naphthyl)methyl]-pyrrolidin-3-yl}benzamide::CHEMBL551134 C-C chemokine receptor type 3 Homo sapiens 230 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297198&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271882 104138729 CHEMBL551134 ZINC43122218 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515463 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C28H25FN2O/c29-24-13-12-22-16-20(10-11-23(22)17-24)18-31-15-14-25(19-31)30-28(32)27-9-5-4-8-26(27)21-6-2-1-3-7-21/h1-13,16-17,25H,14-15,18-19H2,(H,30,32)/t25-/m1/s1 FGPQEWJLDPWKKV-RUZDIDTESA-N 50297199 CHEMBL562475::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 140 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297199&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45267629 104138730 CHEMBL562475 ZINC43068561 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515464 Fc1ccc2cc(CN3CC[C@@H](C3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C28H25FN2O/c29-24-13-12-22-16-20(10-11-23(22)17-24)18-31-15-14-25(19-31)30-28(32)27-9-5-4-8-26(27)21-6-2-1-3-7-21/h1-13,16-17,25H,14-15,18-19H2,(H,30,32)/t25-/m0/s1 FGPQEWJLDPWKKV-VWLOTQADSA-N 50297200 CHEMBL563319::N-{(3S)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 2500 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297200&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45269385 104138731 CHEMBL563319 ZINC43068566 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515465 Fc1ccc2cc(CN3CCC(C3)C(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C28H24FNO/c29-25-13-12-22-16-20(10-11-23(22)17-25)18-30-15-14-24(19-30)28(31)27-9-5-4-8-26(27)21-6-2-1-3-7-21/h1-13,16-17,24H,14-15,18-19H2 GVJBLPDTPTULKQ-UHFFFAOYSA-N 50297201 CHEMBL561941::N-{(rac)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 320 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297201&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45268519 104138732 CHEMBL561941 ZINC43014741 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515466 Fc1ccc2cc(CN3CCCC(C3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C29H27FN2O/c30-25-15-14-23-17-21(12-13-24(23)18-25)19-32-16-6-9-26(20-32)31-29(33)28-11-5-4-10-27(28)22-7-2-1-3-8-22/h1-5,7-8,10-15,17-18,26H,6,9,16,19-20H2,(H,31,33) GDDUTDROJXVVIG-UHFFFAOYSA-N 50297202 (rac)-N-{1-[(6-Fluoro-2-naphthyl)methyl]piperidin-3-yl}-biphenyl-2-carboxamide::CHEMBL549302 C-C chemokine receptor type 3 Homo sapiens 550 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297202&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 45271905 104138733 CHEMBL549302 ZINC43020087 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515467 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C29H27FN2O/c30-25-13-12-23-18-21(10-11-24(23)19-25)20-32-16-14-26(15-17-32)31-29(33)28-9-5-4-8-27(28)22-6-2-1-3-7-22/h1-13,18-19,26H,14-17,20H2,(H,31,33) ZNVHQCHVPKEWRW-UHFFFAOYSA-N 50225349 CHEMBL409830::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)biphenyl-2-carboxamide::N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225349&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44451928 104096673 CHEMBL409830 ZINC29064439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515468 [O-][n+]1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccc3cc(F)ccc3c2)c(c1)C(=O)N1CCCCC1 InChI=1S/C30H33FN4O3/c31-23-7-6-21-14-20(4-5-22(21)15-23)18-35-25-8-9-26(35)17-24(16-25)32-29(36)27-10-13-34(38)19-28(27)30(37)33-11-2-1-3-12-33/h4-7,10,13-15,19,24-26H,1-3,8-9,11-12,16-18H2,(H,32,36)/t25-,26-/m1/s1 SBJLPUIBYIEHFY-CLJLJLNGSA-N 50264212 CHEMBL519042::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)isonicotinamide 1-oxide C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264212&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579713 104112290 CHEMBL519042 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50515469 Fc1ccc2cc(CN3C4CCC3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35) DBWKEBCQXCVXLS-UHFFFAOYSA-N 50264142 Biphenyl-2-carboxylic acid [(1R,5R)-8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::Biphenyl-2-carboxylic acid [8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::CHEMBL522295::N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmc.2009.06.066 10.7270/Q2WD40NV 19620010 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Ohno, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264142&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24882359 104112248 CHEMBL522295 ZINC40423972 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50558760 CCCC[C@H]1CN(CC2CCOCC2)C(=O)OC11CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C InChI=1S/C31H49N5O4/c1-5-6-7-26-21-35(20-25-8-18-39-19-9-25)29(38)40-31(26)12-16-36(17-13-31)30(4)10-14-34(15-11-30)28(37)27-23(2)32-22-33-24(27)3/h22,25-26H,5-21H2,1-4H3/t26-/m0/s1 CXXVJZRGOOIVOD-SANMLTNESA-N 50310739 (S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one::CHEMBL1078231 C-C chemokine receptor type 3 Homo sapiens >50000 ChEMBL 10.1016/j.bmcl.2009.07.122 10.7270/Q25H7GD5 19674898 Rotstein, DM; Gabriel, SD; Makra, F; Filonova, L; Gleason, S; Brotherton-Pleiss, C; Setti, LQ; Trejo-Martin, A; Lee, EK; Sankuratri, S; Ji, C; Derosier, A; Dioszegi, M; Heilek, G; Jekle, A; Berry, P; Weller, P; Mau, CI Roche Palo Alto LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310739&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44555481 104145100 CHEMBL1078231 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50629276 CC(C)Oc1cccc(NC(=O)NC(=O)c2cc3c(C)nn(C)c3nc2N(C)CCN(C)C)c1 InChI=1S/C24H33N7O3/c1-15(2)34-18-10-8-9-17(13-18)25-24(33)27-23(32)20-14-19-16(3)28-31(7)22(19)26-21(20)30(6)12-11-29(4)5/h8-10,13-15H,11-12H2,1-7H3,(H2,25,27,32,33) MFORNGKVWCJAME-UHFFFAOYSA-N 50339636 1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea Hydrochloride::CHEMBL1688889 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1021/jm1012903 10.7270/Q28K79DQ 21341682 Laborde, E; Macsata, RW; Meng, F; Peterson, BT; Robinson, L; Schow, SR; Simon, RJ; Xu, H; Baba, K; Inagaki, H; Ishiwata, Y; Jomori, T; Matsumoto, Y; Miyachi, A; Nakamura, T; Okamoto, M; Handel, TM; Bernard, CC Telik, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9956238 125089738 CHEMBL1688889 ZINC34049016 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50629279 CC(C)Oc1cccc(NC(=O)NC(=O)c2cc3c(C)nn(C)c3nc2N(C)CCN(C)C)c1 InChI=1S/C24H33N7O3/c1-15(2)34-18-10-8-9-17(13-18)25-24(33)27-23(32)20-14-19-16(3)28-31(7)22(19)26-21(20)30(6)12-11-29(4)5/h8-10,13-15H,11-12H2,1-7H3,(H2,25,27,32,33) MFORNGKVWCJAME-UHFFFAOYSA-N 50339636 1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea Hydrochloride::CHEMBL1688889 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1021/jm1012903 10.7270/Q28K79DQ 21341682 Laborde, E; Macsata, RW; Meng, F; Peterson, BT; Robinson, L; Schow, SR; Simon, RJ; Xu, H; Baba, K; Inagaki, H; Ishiwata, Y; Jomori, T; Matsumoto, Y; Miyachi, A; Nakamura, T; Okamoto, M; Handel, TM; Bernard, CC Telik, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339636&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9956238 125089738 CHEMBL1688889 ZINC34049016 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50698810 Fc1ccc(cc1)C1CCN(CCCNC(=O)C2=Cc3cc(Br)ccc3OCC2)CC1 InChI=1S/C25H28BrFN2O2/c26-22-4-7-24-21(17-22)16-20(10-15-31-24)25(30)28-11-1-12-29-13-8-19(9-14-29)18-2-5-23(27)6-3-18/h2-7,16-17,19H,1,8-15H2,(H,28,30) BOHSWBWGIHBCLE-UHFFFAOYSA-N 50355895 CHEMBL1910161 C-C chemokine receptor type 3 Homo sapiens 1000 ChEMBL 10.1016/j.bmcl.2011.09.013 10.7270/Q2XS5VTX 21940167 Bhalay, G; Albrecht, B; Akhlaq, M; Baettig, U; Beer, D; Brown, Z; Charlton, S; Dunstan, A; Bradley, M; Gedeck, P; Glen, A; Howe, T; Keller, T; Leighton-Davies, J; Li, A; McCarthy, C; Mocquet, C; Owen, C; Nicklin, P; Rosethorne, E Novartis Institutes of BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355895&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57401421 136959919 CHEMBL1910161 ZINC73157891 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50698811 COc1ccc(OC)c(c1)S(=O)(=O)N1CCC(CN2CCN(Cc3ccc(F)cc3)CC2)CC1 InChI=1S/C25H34FN3O4S/c1-32-23-7-8-24(33-2)25(17-23)34(30,31)29-11-9-21(10-12-29)19-28-15-13-27(14-16-28)18-20-3-5-22(26)6-4-20/h3-8,17,21H,9-16,18-19H2,1-2H3 NYKKCFFCPZTCGP-UHFFFAOYSA-N 50355897 CHEMBL1910163 C-C chemokine receptor type 3 Homo sapiens 65 ChEMBL 10.1016/j.bmcl.2011.09.013 10.7270/Q2XS5VTX 21940167 Bhalay, G; Albrecht, B; Akhlaq, M; Baettig, U; Beer, D; Brown, Z; Charlton, S; Dunstan, A; Bradley, M; Gedeck, P; Glen, A; Howe, T; Keller, T; Leighton-Davies, J; Li, A; McCarthy, C; Mocquet, C; Owen, C; Nicklin, P; Rosethorne, E Novartis Institutes of BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355897&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11511522 136959921 CHEMBL1910163 ZINC43105085 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50698812 COc1ccc(Cl)cc1NC(=O)NCCCCN(C)Cc1ccc(F)cc1 InChI=1S/C20H25ClFN3O2/c1-25(14-15-5-8-17(22)9-6-15)12-4-3-11-23-20(26)24-18-13-16(21)7-10-19(18)27-2/h5-10,13H,3-4,11-12,14H2,1-2H3,(H2,23,24,26) CANCPAWZPRNGTH-UHFFFAOYSA-N 50355898 CHEMBL1910164 C-C chemokine receptor type 3 Homo sapiens 82 ChEMBL 10.1016/j.bmcl.2011.09.013 10.7270/Q2XS5VTX 21940167 Bhalay, G; Albrecht, B; Akhlaq, M; Baettig, U; Beer, D; Brown, Z; Charlton, S; Dunstan, A; Bradley, M; Gedeck, P; Glen, A; Howe, T; Keller, T; Leighton-Davies, J; Li, A; McCarthy, C; Mocquet, C; Owen, C; Nicklin, P; Rosethorne, E Novartis Institutes of BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355898&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57398008 136959922 CHEMBL1910164 ZINC73261821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50698813 Fc1ccc(OC2CCN(CCCCNC(=O)Nc3ccc(F)c(F)c3)C2)cc1 InChI=1S/C21H24F3N3O2/c22-15-3-6-17(7-4-15)29-18-9-12-27(14-18)11-2-1-10-25-21(28)26-16-5-8-19(23)20(24)13-16/h3-8,13,18H,1-2,9-12,14H2,(H2,25,26,28) MCJUGFQQIQFBPW-UHFFFAOYSA-N 50355899 CHEMBL1910165 C-C chemokine receptor type 3 Homo sapiens 76 ChEMBL 10.1016/j.bmcl.2011.09.013 10.7270/Q2XS5VTX 21940167 Bhalay, G; Albrecht, B; Akhlaq, M; Baettig, U; Beer, D; Brown, Z; Charlton, S; Dunstan, A; Bradley, M; Gedeck, P; Glen, A; Howe, T; Keller, T; Leighton-Davies, J; Li, A; McCarthy, C; Mocquet, C; Owen, C; Nicklin, P; Rosethorne, E Novartis Institutes of BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355899&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57394442 136959923 CHEMBL1910165 ZINC73129358 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50698814 COc1ccc(OC)c(c1)S(=O)(=O)N1CCC(CN2CCC(Cc3ccc(F)cc3)CC2)CC1 InChI=1S/C26H35FN2O4S/c1-32-24-7-8-25(33-2)26(18-24)34(30,31)29-15-11-22(12-16-29)19-28-13-9-21(10-14-28)17-20-3-5-23(27)6-4-20/h3-8,18,21-22H,9-17,19H2,1-2H3 WHGLMSULBHVGIP-UHFFFAOYSA-N 50355900 CHEMBL1910167 C-C chemokine receptor type 3 Homo sapiens 1190 ChEMBL 10.1016/j.bmcl.2011.09.013 10.7270/Q2XS5VTX 21940167 Bhalay, G; Albrecht, B; Akhlaq, M; Baettig, U; Beer, D; Brown, Z; Charlton, S; Dunstan, A; Bradley, M; Gedeck, P; Glen, A; Howe, T; Keller, T; Leighton-Davies, J; Li, A; McCarthy, C; Mocquet, C; Owen, C; Nicklin, P; Rosethorne, E Novartis Institutes of BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355900&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 57392726 136959924 CHEMBL1910167 ZINC73129500 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739451 CC(C)C(CN1CC2CCC1CC2Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(C)cc1 InChI=1S/C27H34Cl2N2O/c1-17(2)26(30-27(32)20-7-4-18(3)5-8-20)16-31-15-21-9-10-23(31)14-22(21)12-19-6-11-24(28)25(29)13-19/h4-8,11,13,17,21-23,26H,9-10,12,14-16H2,1-3H3,(H,30,32) ZAUGGEMEVXODPN-UHFFFAOYSA-N 50133788 CHEMBL331672::N-{1-[5-(3,4-Dichloro-benzyl)-2-aza-bicyclo[2.2.2]oct-2-ylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 5300 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133788&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22022834 104024542 CHEMBL331672 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739452 C[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O InChI=1S/C25H32ClN3O3S/c1-17(27-25(30)28-21-4-3-5-24(15-21)33(2,31)32)16-29-22-10-11-23(29)14-19(13-22)12-18-6-8-20(26)9-7-18/h3-9,15,17,19,22-23H,10-14,16H2,1-2H3,(H2,27,28,30)/t17-,19?,22?,23?/m1/s1 QDNRONLZDDMDPZ-UINAOQCUSA-N 50133789 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3-methanesulfonyl-phenyl)-urea::CHEMBL436363 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133789&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346154 104024543 CHEMBL436363 ZINC13553782 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739453 CC(C)C(CN1C2CCC1CC(Cc1ccc(Cl)c(Cl)c1)C2)NC(=O)c1ccc(C)cc1 InChI=1S/C27H34Cl2N2O/c1-17(2)26(30-27(32)21-7-4-18(3)5-8-21)16-31-22-9-10-23(31)14-20(13-22)12-19-6-11-24(28)25(29)15-19/h4-8,11,15,17,20,22-23,26H,9-10,12-14,16H2,1-3H3,(H,30,32) BAXRBHJRTJSVAQ-UHFFFAOYSA-N 50133790 CHEMBL123308::N-{1-[3-(3,4-Dichloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 1800 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133790&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22022826 104024544 CHEMBL123308 ZINC13553780 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739454 CC(C)C(CC1CCN(Cc2ccc(C)c(C)c2)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C27H38N2O/c1-19(2)26(28-27(30)25-10-6-20(3)7-11-25)17-23-12-14-29(15-13-23)18-24-9-8-21(4)22(5)16-24/h6-11,16,19,23,26H,12-15,17-18H2,1-5H3,(H,28,30) YSUZANLXQIVPEN-UHFFFAOYSA-N 50133791 CHEMBL120957::N-{1-[1-(3,4-Dimethyl-benzyl)-piperidin-4-ylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 7800 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133791&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346023 104024545 CHEMBL120957 ZINC13553772 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739457 CC(C)C(CN1CCC(Cc2ccc(Cl)c(Cl)c2)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C25H32Cl2N2O/c1-17(2)24(28-25(30)21-7-4-18(3)5-8-21)16-29-12-10-19(11-13-29)14-20-6-9-22(26)23(27)15-20/h4-9,15,17,19,24H,10-14,16H2,1-3H3,(H,28,30) GNVXCJBQOWUGAI-UHFFFAOYSA-N 50133795 CHEMBL123943::N-{1-[4-(3,4-Dichloro-benzyl)-piperidin-1-ylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133795&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22257689 104024549 CHEMBL123943 ZINC13553766 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739458 CC(C)C(CC1CCC(Cc2ccc(Cl)c(Cl)c2)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C26H33Cl2NO/c1-17(2)25(29-26(30)22-11-4-18(3)5-12-22)16-20-8-6-19(7-9-20)14-21-10-13-23(27)24(28)15-21/h4-5,10-13,15,17,19-20,25H,6-9,14,16H2,1-3H3,(H,29,30) FXJONMXNOHTESX-UHFFFAOYSA-N 50133794 CHEMBL121588::N-{1-[4-(3,4-Dichloro-benzyl)-cyclohexylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens >200000 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133794&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346022 104024548 CHEMBL121588 ZINC13553768 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739460 C[C@H](O)[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O InChI=1S/C26H34ClN3O4S/c1-17(31)25(29-26(32)28-21-4-3-5-24(15-21)35(2,33)34)16-30-22-10-11-23(30)14-19(13-22)12-18-6-8-20(27)9-7-18/h3-9,15,17,19,22-23,25,31H,10-14,16H2,1-2H3,(H2,28,29,32)/t17-,19?,22?,23?,25-/m0/s1 SXSOGNHLWNMVOY-IEJFQWGMSA-N 50133792 1-{(S)-1-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-2-hydroxy-propyl}-3-(3-methanesulfonyl-phenyl)-urea::CHEMBL121637 C-C chemokine receptor type 3 Homo sapiens 4.4 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133792&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346153 104024546 CHEMBL121637 ZINC13553783 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739462 CC(C)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C25H34N2O/c1-19(2)24(26-25(28)23-11-9-20(3)10-12-23)17-21-13-15-27(16-14-21)18-22-7-5-4-6-8-22/h4-12,19,21,24H,13-18H2,1-3H3,(H,26,28) JHASXLKKMOPARW-UHFFFAOYSA-N 50133797 CHEMBL121743::N-[1-(1-Benzyl-piperidin-4-ylmethyl)-2-methyl-propyl]-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens >200000 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133797&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346218 104024551 CHEMBL121743 ZINC13553770 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739463 CC(C)C(CC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C25H32Cl2N2O/c1-17(2)24(28-25(30)21-7-4-18(3)5-8-21)15-19-10-12-29(13-11-19)16-20-6-9-22(26)23(27)14-20/h4-9,14,17,19,24H,10-13,15-16H2,1-3H3,(H,28,30) DLVIZPKIHPEVAO-UHFFFAOYSA-N 50133798 CHEMBL331702::N-{1-[1-(3,4-Dichloro-benzyl)-piperidin-4-ylmethyl]-2-methyl-propyl}-4-methyl-benzamide C-C chemokine receptor type 3 Homo sapiens 1700 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133798&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 20613253 104024552 CHEMBL331702 ZINC13553776 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739465 Nc1ccc2nc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)sc2c1 InChI=1S/C21H22Cl2N4OS2/c22-16-3-1-13(9-17(16)23)11-27-7-5-15(6-8-27)25-20(28)12-29-21-26-18-4-2-14(24)10-19(18)30-21/h1-4,9-10,15H,5-8,11-12,24H2,(H,25,28) QOHFBKIKGAINLL-UHFFFAOYSA-N 50099482 2-(6-Amino-benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL20921 C-C chemokine receptor type 3 Homo sapiens 2.3 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9913085 103996353 CHEMBL20921 796 ZINC00602832 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739466 CC(C)C(CC1CCN(Cc2ccc(cc2)[N+]([O-])=O)CC1)NC(=O)c1ccc(C)cc1 InChI=1S/C25H33N3O3/c1-18(2)24(26-25(29)22-8-4-19(3)5-9-22)16-20-12-14-27(15-13-20)17-21-6-10-23(11-7-21)28(30)31/h4-11,18,20,24H,12-17H2,1-3H3,(H,26,29) QJHAIHSQKPNUER-UHFFFAOYSA-N 50133799 4-Methyl-N-{2-methyl-1-[1-(4-nitro-benzyl)-piperidin-4-ylmethyl]-propyl}-benzamide::CHEMBL333040 C-C chemokine receptor type 3 Homo sapiens 8500 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133799&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346178 104024553 CHEMBL333040 ZINC13553774 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739469 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50739470 COc1cc(NC(=O)NC(CC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)C(C)C)cc(OC)c1OC InChI=1S/C27H37Cl2N3O4/c1-17(2)23(31-27(33)30-20-14-24(34-3)26(36-5)25(15-20)35-4)13-18-8-10-32(11-9-18)16-19-6-7-21(28)22(29)12-19/h6-7,12,14-15,17-18,23H,8-11,13,16H2,1-5H3,(H2,30,31,33) OCFVRBOTVITVCK-UHFFFAOYSA-N 50133800 1-{1-[1-(3,4-Dichloro-benzyl)-piperidin-4-ylmethyl]-2-methyl-propyl}-3-(3,4,5-trimethoxy-phenyl)-urea::CHEMBL420709 C-C chemokine receptor type 3 Homo sapiens 500 ChEMBL 10.1016/s0960-894x(03)00748-0 10.7270/Q228085J 14505678 Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Roche Palo Alto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133800&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44346211 104024554 CHEMBL420709 ZINC27180474 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50834233 C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)\C=C\c1ccc(Cl)cc1NC(C)=O InChI=1S/C23H25ClFN3O2/c1-16-14-27(15-18-3-8-21(25)9-4-18)11-12-28(16)23(30)10-6-19-5-7-20(24)13-22(19)26-17(2)29/h3-10,13,16H,11-12,14-15H2,1-2H3,(H,26,29)/b10-6+/t16-/m1/s1 DUFKTZBQJIHIAQ-VGZDNEPHSA-N 50174702 (R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide::CHEMBL198949 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1016/j.bmcl.2005.08.057 10.7270/Q2C53MMD 16198561 Revesz, L; Bollbuck, B; Buhl, T; Eder, J; Esser, R; Feifel, R; Heng, R; Hiestand, P; Jachez-Demange, B; Loetscher, P; Sparrer, H; Schlapbach, A; Waelchli, R Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174702&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11743399 104060492 CHEMBL198949 ZINC13985934 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863361 CC1(CCN(Cc2ccc3cc(F)ccc3c2)CC1)NC(=O)c1ccccc1-c1ccccc1 InChI=1S/C30H29FN2O/c1-30(32-29(34)28-10-6-5-9-27(28)23-7-3-2-4-8-23)15-17-33(18-16-30)21-22-11-12-25-20-26(31)14-13-24(25)19-22/h2-14,19-20H,15-18,21H2,1H3,(H,32,34) GWYXBOAOMUWHGP-UHFFFAOYSA-N 50375005 CHEMBL412072 C-C chemokine receptor type 3 Homo sapiens 2800 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375005&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452220 160854095 CHEMBL412072 ZINC29123430 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863362 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3cccc(Oc4ccccc4)c3)ccc2c1 InChI=1S/C29H27FN2O2/c30-25-12-11-22-17-21(9-10-23(22)18-25)20-32-15-13-26(14-16-32)31-29(33)24-5-4-8-28(19-24)34-27-6-2-1-3-7-27/h1-12,17-19,26H,13-16,20H2,(H,31,33) PXGIQYNLHCMNIF-UHFFFAOYSA-N 50375006 CHEMBL412061 C-C chemokine receptor type 3 Homo sapiens 1100 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375006&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44451981 160854096 CHEMBL412061 ZINC29123119 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863363 COc1cccc(c1)C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C24H25FN2O2/c1-29-23-4-2-3-20(15-23)24(28)26-22-9-11-27(12-10-22)16-17-5-6-19-14-21(25)8-7-18(19)13-17/h2-8,13-15,22H,9-12,16H2,1H3,(H,26,28) RXMWAGHSIVJUIT-UHFFFAOYSA-N 50375007 CHEMBL406296 C-C chemokine receptor type 3 Homo sapiens 3500 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375007&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452044 160854097 CHEMBL406296 ZINC29123195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863364 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3F)ccc2c1 InChI=1S/C23H22F2N2O/c24-19-8-7-17-13-16(5-6-18(17)14-19)15-27-11-9-20(10-12-27)26-23(28)21-3-1-2-4-22(21)25/h1-8,13-14,20H,9-12,15H2,(H,26,28) PGBWNUGAHUIGEF-UHFFFAOYSA-N 50375008 CHEMBL261574 C-C chemokine receptor type 3 Homo sapiens 2900 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375008&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452119 160854098 CHEMBL261574 ZINC29123274 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863365 Fc1ccc2cc(CN3CCC(CC3)C(=O)Nc3ccccc3)ccc2c1 InChI=1S/C23H23FN2O/c24-21-9-8-19-14-17(6-7-20(19)15-21)16-26-12-10-18(11-13-26)23(27)25-22-4-2-1-3-5-22/h1-9,14-15,18H,10-13,16H2,(H,25,27) KIBJRAQKTXFONV-UHFFFAOYSA-N 50375009 CHEMBL260900 C-C chemokine receptor type 3 Homo sapiens 1700 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375009&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452250 160854099 CHEMBL260900 ZINC29123495 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863366 Fc1ccc(cc1)C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C23H22F2N2O/c24-20-6-3-17(4-7-20)23(28)26-22-9-11-27(12-10-22)15-16-1-2-19-14-21(25)8-5-18(19)13-16/h1-8,13-14,22H,9-12,15H2,(H,26,28) GVYDSNDGNRGVMY-UHFFFAOYSA-N 50225353 4-fluoro-N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)benzamide::4-fluoro-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide::CHEMBL408407 C-C chemokine receptor type 3 Homo sapiens 640 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225353&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452086 104096674 CHEMBL408407 ZINC29123235 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863367 Fc1cccc(c1)C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C23H22F2N2O/c24-20-3-1-2-19(14-20)23(28)26-22-8-10-27(11-9-22)15-16-4-5-18-13-21(25)7-6-17(18)12-16/h1-7,12-14,22H,8-11,15H2,(H,26,28) UCXOJQUVLVENFV-UHFFFAOYSA-N 50375010 CHEMBL406468 C-C chemokine receptor type 3 Homo sapiens 670 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375010&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452120 160854100 CHEMBL406468 ZINC29123275 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863368 Fc1ccc2cc(CN3CCC(CC3)OC(=O)Nc3ccccc3)ccc2c1 InChI=1S/C23H23FN2O2/c24-20-9-8-18-14-17(6-7-19(18)15-20)16-26-12-10-22(11-13-26)28-23(27)25-21-4-2-1-3-5-21/h1-9,14-15,22H,10-13,16H2,(H,25,27) NSHYFOQUYAADRX-UHFFFAOYSA-N 50375011 CHEMBL258997 C-C chemokine receptor type 3 Homo sapiens 4800 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375011&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452172 160854101 CHEMBL258997 ZINC29123341 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863369 Fc1ccc2cc(CN3CCC(CC3)NC(=O)\C=C\c3ccccc3)ccc2c1 InChI=1S/C25H25FN2O/c26-23-10-9-21-16-20(6-8-22(21)17-23)18-28-14-12-24(13-15-28)27-25(29)11-7-19-4-2-1-3-5-19/h1-11,16-17,24H,12-15,18H2,(H,27,29)/b11-7+ CBQSNFCXAYXVQO-YRNVUSSQSA-N 50225356 (2E)-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}-3-phenylacrylamide::CHEMBL408486::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)cinnamamide C-C chemokine receptor type 3 Homo sapiens 9700 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225356&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452198 104096675 CHEMBL408486 ZINC29123377 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863370 CN(C1CCN(Cc2ccc3cc(F)ccc3c2)CC1)C(=O)c1ccccc1 InChI=1S/C24H25FN2O/c1-26(24(28)19-5-3-2-4-6-19)23-11-13-27(14-12-23)17-18-7-8-21-16-22(25)10-9-20(21)15-18/h2-10,15-16,23H,11-14,17H2,1H3 PJFNGXMYVBZEKR-UHFFFAOYSA-N 50375012 CHEMBL260899 C-C chemokine receptor type 3 Homo sapiens 810 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375012&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452248 160854102 CHEMBL260899 ZINC29123491 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863371 Fc1ccc2cc(CN3CCC(CC3)NS(=O)(=O)c3ccccc3)ccc2c1 InChI=1S/C22H23FN2O2S/c23-20-9-8-18-14-17(6-7-19(18)15-20)16-25-12-10-21(11-13-25)24-28(26,27)22-4-2-1-3-5-22/h1-9,14-15,21,24H,10-13,16H2 RFMGBTLWCRLFSG-UHFFFAOYSA-N 50375013 CHEMBL258790 C-C chemokine receptor type 3 Homo sapiens 830 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375013&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452280 160854103 CHEMBL258790 ZINC29123569 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863372 Fc1ccc2cc(CN3CCC(CC3)NCc3ccccc3)ccc2c1 InChI=1S/C23H25FN2/c24-22-9-8-20-14-19(6-7-21(20)15-22)17-26-12-10-23(11-13-26)25-16-18-4-2-1-3-5-18/h1-9,14-15,23,25H,10-13,16-17H2 OHGPALNUHJEHDY-UHFFFAOYSA-N 50375014 CHEMBL408368 C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375014&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452304 160854104 CHEMBL408368 ZINC29123627 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863373 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3)ccc2c1 InChI=1S/C23H23FN2O/c24-21-9-8-19-14-17(6-7-20(19)15-21)16-26-12-10-22(11-13-26)25-23(27)18-4-2-1-3-5-18/h1-9,14-15,22H,10-13,16H2,(H,25,27) KMIVFOQFRIPVDV-UHFFFAOYSA-N 50192167 CHEMBL214726::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)benzamide::N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide C-C chemokine receptor type 3 Homo sapiens 1300 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192167&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 2729098 104075119 CHEMBL214726 ZINC04336620 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863374 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C29H27FN2O/c30-25-13-12-23-18-21(10-11-24(23)19-25)20-32-16-14-26(15-17-32)31-29(33)28-9-5-4-8-27(28)22-6-2-1-3-7-22/h1-13,18-19,26H,14-17,20H2,(H,31,33) ZNVHQCHVPKEWRW-UHFFFAOYSA-N 50225349 CHEMBL409830::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)biphenyl-2-carboxamide::N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225349&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44451928 104096673 CHEMBL409830 ZINC29064439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863375 Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3Oc3ccccc3)ccc2c1 InChI=1S/C29H27FN2O2/c30-24-13-12-22-18-21(10-11-23(22)19-24)20-32-16-14-25(15-17-32)31-29(33)27-8-4-5-9-28(27)34-26-6-2-1-3-7-26/h1-13,18-19,25H,14-17,20H2,(H,31,33) HKYVHRBKOWJRPW-UHFFFAOYSA-N 50375015 CHEMBL410041 C-C chemokine receptor type 3 Homo sapiens 95 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375015&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44451983 160854105 CHEMBL410041 ZINC29123121 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863376 COc1ccc(cc1)C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C24H25FN2O2/c1-29-23-8-5-18(6-9-23)24(28)26-22-10-12-27(13-11-22)16-17-2-3-20-15-21(25)7-4-19(20)14-17/h2-9,14-15,22H,10-13,16H2,1H3,(H,26,28) VWTJMAOQPMDKDB-UHFFFAOYSA-N 50375016 CHEMBL259409 C-C chemokine receptor type 3 Homo sapiens 2400 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375016&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452009 160854106 CHEMBL259409 ZINC29123156 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863377 COc1ccccc1C(=O)NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C24H25FN2O2/c1-29-23-5-3-2-4-22(23)24(28)26-21-10-12-27(13-11-21)16-17-6-7-19-15-20(25)9-8-18(19)14-17/h2-9,14-15,21H,10-13,16H2,1H3,(H,26,28) MMFNQGNFRBPQPS-UHFFFAOYSA-N 50375017 CHEMBL260649 C-C chemokine receptor type 3 Homo sapiens 720 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375017&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452083 160854107 CHEMBL260649 ZINC29123232 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863378 Fc1ccc(\C=C\CN2CCC(CC2)NC(=O)c2ccccc2)cc1 InChI=1S/C21H23FN2O/c22-19-10-8-17(9-11-19)5-4-14-24-15-12-20(13-16-24)23-21(25)18-6-2-1-3-7-18/h1-11,20H,12-16H2,(H,23,25)/b5-4+ DRDSYHJROZDIBB-SNAWJCMRSA-N 50375018 CHEMBL262588 C-C chemokine receptor type 3 Homo sapiens 3400 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375018&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452361 160854108 CHEMBL262588 ZINC29123744 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863379 Fc1ccc2cc(CN3[C@H]4CC[C@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35)/t27-,28-/m0/s1 DBWKEBCQXCVXLS-NSOVKSMOSA-N 50375019 CHEMBL258996 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375019&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452168 160854109 CHEMBL258996 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50863380 Fc1ccc2cc(CN3[C@H]4CC[C@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35)/t27-,28-/m0/s1 DBWKEBCQXCVXLS-NSOVKSMOSA-N 50375019 CHEMBL258996 C-C chemokine receptor type 3 Homo sapiens 20.0 ChEMBL 10.1016/j.bmc.2007.10.003 10.7270/Q2445NBG 17951061 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Hamada, N; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375019&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44452168 160854109 CHEMBL258996 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875154 Fc1ccc2cc(CN3C4CCC3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35) DBWKEBCQXCVXLS-UHFFFAOYSA-N 50264142 Biphenyl-2-carboxylic acid [(1R,5R)-8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::Biphenyl-2-carboxylic acid [8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::CHEMBL522295::N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264142&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24882359 104112248 CHEMBL522295 ZINC40423972 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875155 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccncc3)ccc2c1 InChI=1S/C30H28FN3O/c31-24-8-7-22-15-20(5-6-23(22)16-24)19-34-26-9-10-27(34)18-25(17-26)33-30(35)29-4-2-1-3-28(29)21-11-13-32-14-12-21/h1-8,11-16,25-27H,9-10,17-19H2,(H,33,35)/t26-,27-/m1/s1 ORBGIALYWQHFBH-KAYWLYCHSA-N 50264143 CHEMBL491199::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-pyridin-4-ylbenzamide C-C chemokine receptor type 3 Homo sapiens 613 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264143&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579653 104112249 CHEMBL491199 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875156 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3cccnc3)ccc2c1 InChI=1S/C30H28FN3O/c31-24-10-9-21-14-20(7-8-22(21)15-24)19-34-26-11-12-27(34)17-25(16-26)33-30(35)29-6-2-1-5-28(29)23-4-3-13-32-18-23/h1-10,13-15,18,25-27H,11-12,16-17,19H2,(H,33,35)/t26-,27-/m1/s1 CYKQNCMKOMGRMR-KAYWLYCHSA-N 50264144 CHEMBL524113::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-pyridin-3-ylbenzamide C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264144&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579654 104112250 CHEMBL524113 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875157 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccn3)ccc2c1 InChI=1S/C30H28FN3O/c31-23-11-10-21-15-20(8-9-22(21)16-23)19-34-25-12-13-26(34)18-24(17-25)33-30(35)28-6-2-1-5-27(28)29-7-3-4-14-32-29/h1-11,14-16,24-26H,12-13,17-19H2,(H,33,35)/t25-,26-/m1/s1 LMLBRLQIZFZLOQ-CLJLJLNGSA-N 50264191 CHEMBL492218::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-pyridin-2-ylbenzamide C-C chemokine receptor type 3 Homo sapiens 57 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264191&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579697 104112282 CHEMBL492218 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875158 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3cncnc3)ccc2c1 InChI=1S/C29H27FN4O/c30-23-8-7-20-11-19(5-6-21(20)12-23)17-34-25-9-10-26(34)14-24(13-25)33-29(35)28-4-2-1-3-27(28)22-15-31-18-32-16-22/h1-8,11-12,15-16,18,24-26H,9-10,13-14,17H2,(H,33,35)/t25-,26-/m1/s1 KPKVUFKNQYKTLE-CLJLJLNGSA-N 50377956 CHEMBL1744356 C-C chemokine receptor type 3 Homo sapiens 93 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377956&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579658 160857039 CHEMBL1744356 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875159 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3nccs3)ccc2c1 InChI=1S/C28H26FN3OS/c29-21-8-7-19-13-18(5-6-20(19)14-21)17-32-23-9-10-24(32)16-22(15-23)31-27(33)25-3-1-2-4-26(25)28-30-11-12-34-28/h1-8,11-14,22-24H,9-10,15-17H2,(H,31,33)/t23-,24-/m1/s1 CCQZIJFCSQARFM-DNQXCXABSA-N 50264155 CHEMBL522819::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(1,3-thiazol-2-yl)benzamide C-C chemokine receptor type 3 Homo sapiens 89 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264155&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579659 104112253 CHEMBL522819 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875160 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-n3cccc3)ccc2c1 InChI=1S/C29H28FN3O/c30-23-10-9-21-15-20(7-8-22(21)16-23)19-33-25-11-12-26(33)18-24(17-25)31-29(34)27-5-1-2-6-28(27)32-13-3-4-14-32/h1-10,13-16,24-26H,11-12,17-19H2,(H,31,34)/t25-,26-/m1/s1 KRJJPCYIKDODRF-CLJLJLNGSA-N 50264156 CHEMBL489167::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(1H-pyrrol-1-yl)benzamide C-C chemokine receptor type 3 Homo sapiens 221 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264156&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579660 104112254 CHEMBL489167 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875161 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-n3ccnc3)ccc2c1 InChI=1S/C28H27FN4O/c29-22-8-7-20-13-19(5-6-21(20)14-22)17-33-24-9-10-25(33)16-23(15-24)31-28(34)26-3-1-2-4-27(26)32-12-11-30-18-32/h1-8,11-14,18,23-25H,9-10,15-17H2,(H,31,34)/t24-,25-/m1/s1 GHOPIVHPZQWVRR-JWQCQUIFSA-N 50264205 CHEMBL521747::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(1H-imidazol-1-yl)benzamide C-C chemokine receptor type 3 Homo sapiens 217 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264205&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579706 104112283 CHEMBL521747 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875162 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3OC3CCCCC3)ccc2c1 InChI=1S/C31H35FN2O2/c32-24-13-12-22-16-21(10-11-23(22)17-24)20-34-26-14-15-27(34)19-25(18-26)33-31(35)29-8-4-5-9-30(29)36-28-6-2-1-3-7-28/h4-5,8-13,16-17,25-28H,1-3,6-7,14-15,18-20H2,(H,33,35)/t26-,27-/m1/s1 JOIZQAMGXOUKNX-KAYWLYCHSA-N 50264206 2-(Cyclohexyloxy)-N-{(3-exo)-8-[(6-fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide::CHEMBL488530 C-C chemokine receptor type 3 Homo sapiens 118 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264206&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579707 104112284 CHEMBL488530 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875163 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3N3CCCCC3)ccc2c1 InChI=1S/C30H34FN3O/c31-24-11-10-22-16-21(8-9-23(22)17-24)20-34-26-12-13-27(34)19-25(18-26)32-30(35)28-6-2-3-7-29(28)33-14-4-1-5-15-33/h2-3,6-11,16-17,25-27H,1,4-5,12-15,18-20H2,(H,32,35)/t26-,27-/m1/s1 AIVQQWMRXBLFQN-KAYWLYCHSA-N 50264207 CHEMBL491611::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-piperidin-1-ylbenzamide C-C chemokine receptor type 3 Homo sapiens 279 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264207&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579708 104112285 CHEMBL491611 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875164 CN(C1CCCCC1)C(=O)c1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C33H38FN3O2/c1-36(27-7-3-2-4-8-27)33(39)31-10-6-5-9-30(31)32(38)35-26-19-28-15-16-29(20-26)37(28)21-22-11-12-24-18-25(34)14-13-23(24)17-22/h5-6,9-14,17-18,26-29H,2-4,7-8,15-16,19-21H2,1H3,(H,35,38)/t28-,29-/m1/s1 UFXNOQYBARMPKV-FQLXRVMXSA-N 50264208 CHEMBL499971::N-Cyclohexyl-N'-{(3-exo)-8-[(6-fluoro-2-naphthyl)-methyl]-8-azabicyclo[3.2.1]oct-3-yl}-N-methylphthalamide C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264208&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579709 104112286 CHEMBL499971 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875165 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3C(=O)N3CCCCC3)ccc2c1 InChI=1S/C31H34FN3O2/c32-24-11-10-22-16-21(8-9-23(22)17-24)20-35-26-12-13-27(35)19-25(18-26)33-30(36)28-6-2-3-7-29(28)31(37)34-14-4-1-5-15-34/h2-3,6-11,16-17,25-27H,1,4-5,12-15,18-20H2,(H,33,36)/t26-,27-/m1/s1 ANCXGRSQBYGKRS-KAYWLYCHSA-N 50264157 CHEMBL519750::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(piperidin-1-ylcarbonyl)benzamide C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264157&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579661 104112255 CHEMBL519750 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875166 CN1CCN(CC1)C(=O)c1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H35FN4O2/c1-34-12-14-35(15-13-34)31(38)29-5-3-2-4-28(29)30(37)33-25-18-26-10-11-27(19-25)36(26)20-21-6-7-23-17-24(32)9-8-22(23)16-21/h2-9,16-17,25-27H,10-15,18-20H2,1H3,(H,33,37)/t26-,27-/m1/s1 IABLUIXTFBYBAQ-KAYWLYCHSA-N 50264158 CHEMBL488319::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-[(4-methylpiperazin-1-yl)carbonyl]benzamide C-C chemokine receptor type 3 Homo sapiens 482 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264158&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579662 104112256 CHEMBL488319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875167 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3C(=O)N3CCOCC3)ccc2c1 InChI=1S/C30H32FN3O3/c31-23-8-7-21-15-20(5-6-22(21)16-23)19-34-25-9-10-26(34)18-24(17-25)32-29(35)27-3-1-2-4-28(27)30(36)33-11-13-37-14-12-33/h1-8,15-16,24-26H,9-14,17-19H2,(H,32,35)/t25-,26-/m1/s1 ADTVNUYDDICOCW-CLJLJLNGSA-N 50264159 CHEMBL488529::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(morpholin-4-ylcarbonyl)benzamide C-C chemokine receptor type 3 Homo sapiens 679 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264159&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579663 104112257 CHEMBL488529 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875168 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3C(=O)N3CCCC3)ccc2c1 InChI=1S/C30H32FN3O2/c31-23-10-9-21-15-20(7-8-22(21)16-23)19-34-25-11-12-26(34)18-24(17-25)32-29(35)27-5-1-2-6-28(27)30(36)33-13-3-4-14-33/h1-2,5-10,15-16,24-26H,3-4,11-14,17-19H2,(H,32,35)/t25-,26-/m1/s1 GGNQLULMKHERGH-CLJLJLNGSA-N 50264209 CHEMBL528992::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(pyrrolidin-1-ylcarbonyl)benzamide C-C chemokine receptor type 3 Homo sapiens 225 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264209&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579710 104112287 CHEMBL528992 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875169 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3C(=O)N3CCCCCC3)ccc2c1 InChI=1S/C32H36FN3O2/c33-25-12-11-23-17-22(9-10-24(23)18-25)21-36-27-13-14-28(36)20-26(19-27)34-31(37)29-7-3-4-8-30(29)32(38)35-15-5-1-2-6-16-35/h3-4,7-12,17-18,26-28H,1-2,5-6,13-16,19-21H2,(H,34,37)/t27-,28-/m1/s1 GIPFZYIDTGSYHG-VSGBNLITSA-N 50264210 2-(Azepan-1-ylcarbonyl)-N-{(3-exo)-8-[(6-fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide::CHEMBL530560 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264210&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579711 104112288 CHEMBL530560 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875170 Fc1ccc2cc(CN3C4CCC3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35) DBWKEBCQXCVXLS-UHFFFAOYSA-N 50264142 Biphenyl-2-carboxylic acid [(1R,5R)-8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::Biphenyl-2-carboxylic acid [8-(6-fluoro-naphthalen-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-amide::CHEMBL522295::N-(8-((6-fluoronaphthalen-2-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)biphenyl-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 20.0 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264142&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24882359 104112248 CHEMBL522295 ZINC40423972 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875171 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3cccnc3C(=O)N3CCCCC3)ccc2c1 InChI=1S/C30H33FN4O2/c31-23-9-8-21-15-20(6-7-22(21)16-23)19-35-25-10-11-26(35)18-24(17-25)33-29(36)27-5-4-12-32-28(27)30(37)34-13-2-1-3-14-34/h4-9,12,15-16,24-26H,1-3,10-11,13-14,17-19H2,(H,33,36)/t25-,26-/m1/s1 ZEQMOAYYXNSJIC-CLJLJLNGSA-N 50264160 CHEMBL528774::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(piperidin-1-ylcarbonyl)nicotinamide C-C chemokine receptor type 3 Homo sapiens 98 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264160&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579664 104112258 CHEMBL528774 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875172 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccncc3C(=O)N3CCCCC3)ccc2c1 InChI=1S/C30H33FN4O2/c31-23-7-6-21-14-20(4-5-22(21)15-23)19-35-25-8-9-26(35)17-24(16-25)33-29(36)27-10-11-32-18-28(27)30(37)34-12-2-1-3-13-34/h4-7,10-11,14-15,18,24-26H,1-3,8-9,12-13,16-17,19H2,(H,33,36)/t25-,26-/m1/s1 VMQJKUPIPIPSNI-CLJLJLNGSA-N 50264161 CHEMBL488929::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)isonicotinamide C-C chemokine receptor type 3 Homo sapiens 13 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264161&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579665 104112259 CHEMBL488929 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875173 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3cnccc3C(=O)N3CCCCC3)ccc2c1 InChI=1S/C30H33FN4O2/c31-23-7-6-21-14-20(4-5-22(21)15-23)19-35-25-8-9-26(35)17-24(16-25)33-29(36)28-18-32-11-10-27(28)30(37)34-12-2-1-3-13-34/h4-7,10-11,14-15,18,24-26H,1-3,8-9,12-13,16-17,19H2,(H,33,36)/t25-,26-/m1/s1 QVTRULHJJDTVLZ-CLJLJLNGSA-N 50264162 CHEMBL485856::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-4-(piperidin-1-ylcarbonyl)nicotinamide C-C chemokine receptor type 3 Homo sapiens 85 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264162&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579666 104112260 CHEMBL485856 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875174 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ncccc3C(=O)N3CCCCC3)ccc2c1 InChI=1S/C30H33FN4O2/c31-23-9-8-21-15-20(6-7-22(21)16-23)19-35-25-10-11-26(35)18-24(17-25)33-29(36)28-27(5-4-12-32-28)30(37)34-13-2-1-3-14-34/h4-9,12,15-16,24-26H,1-3,10-11,13-14,17-19H2,(H,33,36)/t25-,26-/m1/s1 ROQSRBMFNOPNJL-CLJLJLNGSA-N 50264211 CHEMBL488930::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)pyridine-2-carboxamide C-C chemokine receptor type 3 Homo sapiens 131 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264211&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579712 104112289 CHEMBL488930 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50875175 [O-][n+]1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccc3cc(F)ccc3c2)c(c1)C(=O)N1CCCCC1 InChI=1S/C30H33FN4O3/c31-23-7-6-21-14-20(4-5-22(21)15-23)18-35-25-8-9-26(35)17-24(16-25)32-29(36)27-10-13-34(38)19-28(27)30(37)33-11-2-1-3-12-33/h4-7,10,13-15,19,24-26H,1-3,8-9,11-12,16-18H2,(H,32,36)/t25-,26-/m1/s1 SBJLPUIBYIEHFY-CLJLJLNGSA-N 50264212 CHEMBL519042::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)isonicotinamide 1-oxide C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmc.2008.08.006 10.7270/Q21J9BPZ 18752960 Sato, I; Morihira, K; Inami, H; Kubota, H; Morokata, T; Suzuki, K; Iura, Y; Nitta, A; Imaoka, T; Takahashi, T; Takeuchi, M; Ohta, M; Tsukamoto, S Astellas Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264212&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44579713 104112290 CHEMBL519042 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857790 CCC[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-3-6-23(29-27(37)30-24-9-4-8-21(16-24)26-31-32-33-34(26)2)17-25(36)35-14-5-7-20(18-35)15-19-10-12-22(28)13-11-19/h4,8-13,16,20,23,25,36H,3,5-7,14-15,17-18H2,1-2H3,(H2,29,30,37)/t20-,23+,25+/m0/s1 YVVCYGCCIFEDCL-QUURXOELSA-N 50372824 CHEMBL269933 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372824&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455844 160851925 CHEMBL269933 ZINC29130147 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857791 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1ccnn1)-n1ccnn1 InChI=1S/C27H32FN9O2/c1-19(13-26(38)35-10-2-3-21(18-35)14-20-4-6-22(28)7-5-20)31-27(39)32-23-15-24(36-11-8-29-33-36)17-25(16-23)37-12-9-30-34-37/h4-9,11-12,15-17,19,21,26,38H,2-3,10,13-14,18H2,1H3,(H2,31,32,39)/t19-,21+,26-/m1/s1 GHILKFUWMODLTJ-BNIKKZEQSA-N 50372825 CHEMBL272067 C-C chemokine receptor type 3 Homo sapiens 1.4 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372825&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455482 160851926 CHEMBL272067 ZINC29129155 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857792 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1cccn1)-n1cccn1 InChI=1S/C29H34FN7O2/c1-21(15-28(38)35-12-2-5-23(20-35)16-22-6-8-24(30)9-7-22)33-29(39)34-25-17-26(36-13-3-10-31-36)19-27(18-25)37-14-4-11-32-37/h3-4,6-11,13-14,17-19,21,23,28,38H,2,5,12,15-16,20H2,1H3,(H2,33,34,39)/t21-,23+,28-/m1/s1 MRKMZVYMRPCVIP-ZLIGTFTASA-N 50372826 CHEMBL401879 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372826&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455683 160851927 CHEMBL401879 ZINC29129667 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857793 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(C)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O2/c1-17-11-21(25-30-31-32-33(25)3)15-23(12-17)29-26(36)28-18(2)13-24(35)34-10-4-5-20(16-34)14-19-6-8-22(27)9-7-19/h6-9,11-12,15,18,20,24,35H,4-5,10,13-14,16H2,1-3H3,(H2,28,29,36)/t18-,20+,24-/m1/s1 ITFWHVWTUPHVKE-LJFZDNNRSA-N 50372827 CHEMBL257029 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372827&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455744 160851928 CHEMBL257029 ZINC29129841 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857794 C[C@@H](C[C@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O4/c1-17(29-27(35)30-25-14-22(18(2)32)13-23(15-25)19(3)33)11-26(34)31-10-4-5-21(16-31)12-20-6-8-24(28)9-7-20/h6-9,13-15,17,21,26,34H,4-5,10-12,16H2,1-3H3,(H2,29,30,35)/t17-,21-,26-/m0/s1 BIPWHXLJDZRBGR-CWVVSJDFSA-N 50372828 CHEMBL258309 C-C chemokine receptor type 3 Homo sapiens 2.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372828&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455767 160851929 CHEMBL258309 ZINC29129927 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857795 C[C@H](CC(=O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H30FN7O2/c1-17(27-25(35)28-22-7-3-6-20(15-22)24-29-30-31-32(24)2)13-23(34)33-12-4-5-19(16-33)14-18-8-10-21(26)11-9-18/h3,6-11,15,17,19H,4-5,12-14,16H2,1-2H3,(H2,27,28,35)/t17-,19+/m1/s1 UQBFRDAXMOLPES-MJGOQNOKSA-N 50372829 CHEMBL428071 C-C chemokine receptor type 3 Homo sapiens 4.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372829&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10140602 160851930 CHEMBL428071 ZINC29130081 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857796 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1cccn1)-n1cccn1 InChI=1S/C29H34FN7O/c1-22(10-16-35-13-2-5-24(21-35)17-23-6-8-25(30)9-7-23)33-29(38)34-26-18-27(36-14-3-11-31-36)20-28(19-26)37-15-4-12-32-37/h3-4,6-9,11-12,14-15,18-20,22,24H,2,5,10,13,16-17,21H2,1H3,(H2,33,34,38)/t22-,24+/m1/s1 USWHNYCYCAKUDH-VWNXMTODSA-N 50372830 CHEMBL270147 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372830&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455846 160851931 CHEMBL270147 ZINC29130151 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857797 C[C@@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O3/c1-18(29-27(34)30-26-15-23(19(2)32)14-24(16-26)20(3)33)10-12-31-11-4-5-22(17-31)13-21-6-8-25(28)9-7-21/h6-9,14-16,18,22H,4-5,10-13,17H2,1-3H3,(H2,29,30,34)/t18-,22-/m0/s1 YMMAHNYFXNAREN-AVRDEDQJSA-N 50372831 CHEMBL404202 C-C chemokine receptor type 3 Homo sapiens 5.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372831&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455872 160851932 CHEMBL404202 ZINC29130212 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857798 Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O InChI=1S/C28H36FN7O3/c1-28(2,26(37)38)22-15-21(25-32-33-34-35(25)3)16-24(17-22)31-27(39)30-11-5-13-36-12-4-6-20(18-36)14-19-7-9-23(29)10-8-19/h7-10,15-17,20H,4-6,11-14,18H2,1-3H3,(H,37,38)(H2,30,31,39)/t20-/m0/s1 OMYKGVIQNBTKOU-FQEVSTJZSA-N 50372832 CHEMBL272068 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372832&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455483 160851933 CHEMBL272068 ZINC29129156 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857799 CCc1cc(NC(=O)N[C@H](C)CCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-4-20-15-23(26-31-32-33-34(26)3)17-25(16-20)30-27(36)29-19(2)11-13-35-12-5-6-22(18-35)14-21-7-9-24(28)10-8-21/h7-10,15-17,19,22H,4-6,11-14,18H2,1-3H3,(H2,29,30,36)/t19-,22+/m1/s1 IQUQYZRIYXKKDB-KNQAVFIVSA-N 50372833 CHEMBL427728 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372833&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455509 160851934 CHEMBL427728 ZINC29129200 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857800 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18(12-14-33-13-4-5-20(17-33)15-19-8-10-22(26)11-9-19)27-25(34)28-23-7-3-6-21(16-23)24-29-30-31-32(24)2/h3,6-11,16,18,20H,4-5,12-15,17H2,1-2H3,(H2,27,28,34)/t18-,20+/m1/s1 RRHZFCXDULLQHS-QUCCMNQESA-N 50372834 CHEMBL428775 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372834&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455539 160851935 CHEMBL428775 ZINC29129262 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857801 C[C@H](C[C@@H](C)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-18(28-26(35)29-24-8-4-7-22(16-24)25-30-31-32-33(25)3)14-19(2)34-13-5-6-21(17-34)15-20-9-11-23(27)12-10-20/h4,7-12,16,18-19,21H,5-6,13-15,17H2,1-3H3,(H2,28,29,35)/t18-,19-,21+/m1/s1 YTNCTGOARJJRAX-SBHAEUEKSA-N 50372835 CHEMBL258156 C-C chemokine receptor type 3 Homo sapiens 0.064 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372835&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455766 160851936 CHEMBL258156 ZINC29129925 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857802 CNC(=O)O[C@H](C[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)N1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H35FN8O3/c1-18(30-26(37)31-23-8-4-7-21(16-23)25-32-33-34-35(25)3)14-24(39-27(38)29-2)36-13-5-6-20(17-36)15-19-9-11-22(28)12-10-19/h4,7-12,16,18,20,24H,5-6,13-15,17H2,1-3H3,(H,29,38)(H2,30,31,37)/t18-,20+,24-/m1/s1 VFFNPYOBHDRIJA-LJFZDNNRSA-N 50372836 CHEMBL402331 C-C chemokine receptor type 3 Homo sapiens 0.87 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372836&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455817 160851937 CHEMBL402331 ZINC29130077 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857803 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1ccon1)-c1ccon1 InChI=1S/C29H32FN5O4/c1-19(13-28(36)35-10-2-3-21(18-35)14-20-4-6-24(30)7-5-20)31-29(37)32-25-16-22(26-8-11-38-33-26)15-23(17-25)27-9-12-39-34-27/h4-9,11-12,15-17,19,21,28,36H,2-3,10,13-14,18H2,1H3,(H2,31,32,37)/t19-,21+,28-/m1/s1 KZYSQAFJXXLUSQ-MRFDPFKHSA-N 50372837 CHEMBL429846 C-C chemokine receptor type 3 Homo sapiens 0.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372837&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455458 160851938 CHEMBL429846 ZINC29129114 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857804 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C InChI=1S/C27H34FN5O2/c1-19(30-27(35)31-24-7-3-6-22(17-24)26-29-12-14-32(26)2)15-25(34)33-13-4-5-21(18-33)16-20-8-10-23(28)11-9-20/h3,6-12,14,17,19,21,25,34H,4-5,13,15-16,18H2,1-2H3,(H2,30,31,35)/t19-,21+,25-/m1/s1 FLHWJOBAIDQWDE-FZOAFFARSA-N 50372838 CHEMBL429323 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372838&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455658 160851939 CHEMBL429323 ZINC29129588 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857805 CCc1cc(NC(=O)N[C@H](C)C[C@@H](O)N2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-4-19-14-22(26-31-32-33-34(26)3)16-24(15-19)30-27(37)29-18(2)12-25(36)35-11-5-6-21(17-35)13-20-7-9-23(28)10-8-20/h7-10,14-16,18,21,25,36H,4-6,11-13,17H2,1-3H3,(H2,29,30,37)/t18-,21+,25-/m1/s1 HRZQKGGVQGIRFQ-DHTSOJEISA-N 50372839 CHEMBL437031 C-C chemokine receptor type 3 Homo sapiens 0.013 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372839&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455711 160851940 CHEMBL437031 ZINC29129747 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857806 C[C@@H](C[C@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O4/c1-17(29-27(35)30-25-14-22(18(2)32)13-23(15-25)19(3)33)11-26(34)31-10-4-5-21(16-31)12-20-6-8-24(28)9-7-20/h6-9,13-15,17,21,26,34H,4-5,10-12,16H2,1-3H3,(H2,29,30,35)/t17-,21-,26-/m0/s1 BIPWHXLJDZRBGR-CWVVSJDFSA-N 50372828 CHEMBL258309 C-C chemokine receptor type 3 Homo sapiens >1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372828&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455767 160851929 CHEMBL258309 ZINC29129927 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857807 C[C@H](CC(=O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H30FN7O2/c1-17(27-25(35)28-22-7-3-6-20(15-22)24-29-30-31-32(24)2)13-23(34)33-12-4-5-19(16-33)14-18-8-10-21(26)11-9-18/h3,6-11,15,17,19H,4-5,12-14,16H2,1-2H3,(H2,27,28,35)/t17-,19+/m1/s1 UQBFRDAXMOLPES-MJGOQNOKSA-N 50372829 CHEMBL428071 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372829&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10140602 160851930 CHEMBL428071 ZINC29130081 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857808 Fc1ccc(C[C@@H]2CCCN(CCCNC(=O)Nc3cc(cc(c3)-n3cccn3)-n3cccn3)C2)cc1 InChI=1S/C28H32FN7O/c29-24-8-6-22(7-9-24)17-23-5-1-13-34(21-23)14-2-10-30-28(37)33-25-18-26(35-15-3-11-31-35)20-27(19-25)36-16-4-12-32-36/h3-4,6-9,11-12,15-16,18-20,23H,1-2,5,10,13-14,17,21H2,(H2,30,33,37)/t23-/m0/s1 MJKZXBYUDVUDPD-QHCPKHFHSA-N 50372840 CHEMBL403839 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372840&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455847 160851941 CHEMBL403839 ZINC29130153 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857809 CC(C)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-19(2)22-15-23(26-31-32-33-34(26)3)17-25(16-22)30-27(36)29-11-5-13-35-12-4-6-21(18-35)14-20-7-9-24(28)10-8-20/h7-10,15-17,19,21H,4-6,11-14,18H2,1-3H3,(H2,29,30,36)/t21-/m0/s1 JHSQADBOQIOZCJ-NRFANRHFSA-N 50372841 CHEMBL429604 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372841&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455484 160851942 CHEMBL429604 ZINC29129158 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857810 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18(12-14-33-13-4-5-20(17-33)15-19-8-10-22(26)11-9-19)27-25(34)28-23-7-3-6-21(16-23)24-29-30-31-32(24)2/h3,6-11,16,18,20H,4-5,12-15,17H2,1-2H3,(H2,27,28,34)/t18-,20+/m1/s1 RRHZFCXDULLQHS-QUCCMNQESA-N 50372834 CHEMBL428775 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372834&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455539 160851935 CHEMBL428775 ZINC29129262 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857812 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)C InChI=1S/C28H38FN7O/c1-19(2)23-15-24(27-32-33-34-35(27)4)17-26(16-23)31-28(37)30-20(3)11-13-36-12-5-6-22(18-36)14-21-7-9-25(29)10-8-21/h7-10,15-17,19-20,22H,5-6,11-14,18H2,1-4H3,(H2,30,31,37)/t20-,22+/m1/s1 CAFBEDWUSCRFBS-IRLDBZIGSA-N 50372842 CHEMBL404122 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372842&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455485 160851943 CHEMBL404122 ZINC29129159 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857813 CC(C)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-19(2)22-15-23(26-31-32-33-34(26)3)17-25(16-22)30-27(36)29-11-5-13-35-12-4-6-21(18-35)14-20-7-9-24(28)10-8-20/h7-10,15-17,19,21H,4-6,11-14,18H2,1-3H3,(H2,29,30,36)/t21-/m0/s1 JHSQADBOQIOZCJ-NRFANRHFSA-N 50372841 CHEMBL429604 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372841&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455484 160851942 CHEMBL429604 ZINC29129158 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857814 CCc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-3-19-15-22(25-30-31-32-33(25)2)17-24(16-19)29-26(35)28-11-5-13-34-12-4-6-21(18-34)14-20-7-9-23(27)10-8-20/h7-10,15-17,21H,3-6,11-14,18H2,1-2H3,(H2,28,29,35)/t21-/m0/s1 CLXQASNQVOBRFA-NRFANRHFSA-N 50372843 CHEMBL401545 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372843&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455511 160851944 CHEMBL401545 ZINC29129203 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857815 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(C)cc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-18-13-22(25-30-31-32-33(25)3)16-24(14-18)29-26(35)28-19(2)10-12-34-11-4-5-21(17-34)15-20-6-8-23(27)9-7-20/h6-9,13-14,16,19,21H,4-5,10-12,15,17H2,1-3H3,(H2,28,29,35)/t19-,21+/m1/s1 SPDRJYHRLHGQBR-CTNGQTDRSA-N 50372844 CHEMBL257737 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372844&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455510 160851945 CHEMBL257737 ZINC29129202 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857816 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m0/s1 FDDSQKZQCHXOJV-FQEVSTJZSA-N 50142448 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea::1-(3-Acetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46905 C-C chemokine receptor type 3 Homo sapiens 2.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290039 104031829 CHEMBL46905 ZINC13613375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857817 CC(=O)c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN3O2/c1-18(29)21-6-2-7-23(16-21)27-24(30)26-12-4-14-28-13-3-5-20(17-28)15-19-8-10-22(25)11-9-19/h2,6-11,16,20H,3-5,12-15,17H2,1H3,(H2,26,27,30)/t20-/m0/s1 FDDSQKZQCHXOJV-FQEVSTJZSA-N 50142448 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetylphenyl)urea::1-(3-Acetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46905 C-C chemokine receptor type 3 Homo sapiens 25 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142448&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44290039 104031829 CHEMBL46905 ZINC13613375 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857819 C[C@H](C[C@@H](C)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C26H34FN7O/c1-18(28-26(35)29-24-8-4-7-22(16-24)25-30-31-32-33(25)3)14-19(2)34-13-5-6-21(17-34)15-20-9-11-23(27)12-10-20/h4,7-12,16,18-19,21H,5-6,13-15,17H2,1-3H3,(H2,28,29,35)/t18-,19-,21+/m1/s1 YTNCTGOARJJRAX-SBHAEUEKSA-N 50372835 CHEMBL258156 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372835&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455766 160851936 CHEMBL258156 ZINC29129925 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857820 CCc1cc(NC(=O)N[C@H](C)C[C@@H](N(C)C)N2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C29H41FN8O/c1-6-21-16-24(28-33-34-35-37(28)5)18-26(17-21)32-29(39)31-20(2)14-27(36(3)4)38-13-7-8-23(19-38)15-22-9-11-25(30)12-10-22/h9-12,16-18,20,23,27H,6-8,13-15,19H2,1-5H3,(H2,31,32,39)/t20-,23+,27+/m1/s1 FGWVPTQNIIZCGL-CGHRXAFASA-N 50372845 CHEMBL404585 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372845&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455788 160851946 CHEMBL404585 ZINC29129992 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857821 C[C@H](C[C@@H](NC(C)=O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C27H35FN8O2/c1-18(29-27(38)31-24-8-4-7-22(16-24)26-32-33-34-35(26)3)14-25(30-19(2)37)36-13-5-6-21(17-36)15-20-9-11-23(28)12-10-20/h4,7-12,16,18,21,25H,5-6,13-15,17H2,1-3H3,(H,30,37)(H2,29,31,38)/t18-,21+,25+/m1/s1 JTRFENATSPZVNG-QLWBXOBMSA-N 50372846 CHEMBL404586 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372846&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455791 160851947 CHEMBL404586 ZINC29129996 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857822 C[C@H](C[C@@H](N)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H33FN8O/c1-17(28-25(35)29-22-7-3-6-20(15-22)24-30-31-32-33(24)2)13-23(27)34-12-4-5-19(16-34)14-18-8-10-21(26)11-9-18/h3,6-11,15,17,19,23H,4-5,12-14,16,27H2,1-2H3,(H2,28,29,35)/t17-,19+,23+/m1/s1 KLUPWQNJJYFUHQ-FHJLPGHOSA-N 50372847 CHEMBL258322 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372847&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455790 160851948 CHEMBL258322 ZINC29129994 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857823 CNC(=O)O[C@H](C[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)N1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C27H35FN8O3/c1-18(30-26(37)31-23-8-4-7-21(16-23)25-32-33-34-35(25)3)14-24(39-27(38)29-2)36-13-5-6-20(17-36)15-19-9-11-22(28)12-10-19/h4,7-12,16,18,20,24H,5-6,13-15,17H2,1-3H3,(H,29,38)(H2,30,31,37)/t18-,20+,24-/m1/s1 VFFNPYOBHDRIJA-LJFZDNNRSA-N 50372836 CHEMBL402331 C-C chemokine receptor type 3 Homo sapiens 0.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372836&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455817 160851937 CHEMBL402331 ZINC29130077 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857824 CC(C)C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C28H38FN7O2/c1-19(2)14-25(31-28(38)30-24-8-4-7-22(16-24)27-32-33-34-35(27)3)17-26(37)36-13-5-6-21(18-36)15-20-9-11-23(29)12-10-20/h4,7-12,16,19,21,25-26,37H,5-6,13-15,17-18H2,1-3H3,(H2,30,31,38)/t21-,25+,26+/m0/s1 LVNMVTRHDJLKCU-RMUDUWAUSA-N 50372848 CHEMBL257073 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372848&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455818 160851949 CHEMBL257073 ZINC29130079 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857825 CC(C)[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-18(2)24(30-27(37)29-23-8-4-7-21(15-23)26-31-32-33-34(26)3)16-25(36)35-13-5-6-20(17-35)14-19-9-11-22(28)12-10-19/h4,7-12,15,18,20,24-25,36H,5-6,13-14,16-17H2,1-3H3,(H2,29,30,37)/t20-,24-,25+/m0/s1 YXGHCLLTAXLPMG-KSNOWIBYSA-N 50372849 CHEMBL403838 C-C chemokine receptor type 3 Homo sapiens 0.4 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372849&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455841 160851950 CHEMBL403838 ZINC29130145 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857826 CC[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C26H34FN7O2/c1-3-22(28-26(36)29-23-8-4-7-20(15-23)25-30-31-32-33(25)2)16-24(35)34-13-5-6-19(17-34)14-18-9-11-21(27)12-10-18/h4,7-12,15,19,22,24,35H,3,5-6,13-14,16-17H2,1-2H3,(H2,28,29,36)/t19-,22+,24+/m0/s1 HTZBCHVAMWNYJY-BPUDTRNYSA-N 50372850 CHEMBL270583 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372850&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455871 160851951 CHEMBL270583 ZINC29130210 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857827 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1ccon1)-c1ccon1 InChI=1S/C29H32FN5O4/c1-19(13-28(36)35-10-2-3-21(18-35)14-20-4-6-24(30)7-5-20)31-29(37)32-25-16-22(26-8-11-38-33-26)15-23(17-25)27-9-12-39-34-27/h4-9,11-12,15-17,19,21,28,36H,2-3,10,13-14,18H2,1H3,(H2,31,32,37)/t19-,21+,28-/m1/s1 KZYSQAFJXXLUSQ-MRFDPFKHSA-N 50372837 CHEMBL429846 C-C chemokine receptor type 3 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372837&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455458 160851938 CHEMBL429846 ZINC29129114 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857828 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1ncco1)-c1ncco1 InChI=1S/C29H32FN5O4/c1-19(13-26(36)35-10-2-3-21(18-35)14-20-4-6-24(30)7-5-20)33-29(37)34-25-16-22(27-31-8-11-38-27)15-23(17-25)28-32-9-12-39-28/h4-9,11-12,15-17,19,21,26,36H,2-3,10,13-14,18H2,1H3,(H2,33,34,37)/t19-,21+,26-/m1/s1 WGYRDHMVDDVNRZ-BNIKKZEQSA-N 50372851 CHEMBL255399 C-C chemokine receptor type 3 Homo sapiens 2.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372851&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455460 160851952 CHEMBL255399 ZINC29129116 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857829 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1ccnn1)-n1ccnn1 InChI=1S/C27H32FN9O/c1-20(8-12-35-11-2-3-22(19-35)15-21-4-6-23(28)7-5-21)31-27(38)32-24-16-25(36-13-9-29-33-36)18-26(17-24)37-14-10-30-34-37/h4-7,9-10,13-14,16-18,20,22H,2-3,8,11-12,15,19H2,1H3,(H2,31,32,38)/t20-,22+/m1/s1 DGYXGFPBBALNKC-IRLDBZIGSA-N 50372852 CHEMBL441334 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372852&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455560 160851953 CHEMBL441334 ZINC29129319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857830 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nccs1)-c1nccs1 InChI=1S/C29H32FN5O2S2/c1-19(13-26(36)35-10-2-3-21(18-35)14-20-4-6-24(30)7-5-20)33-29(37)34-25-16-22(27-31-8-11-38-27)15-23(17-25)28-32-9-12-39-28/h4-9,11-12,15-17,19,21,26,36H,2-3,10,13-14,18H2,1H3,(H2,33,34,37)/t19-,21+,26-/m1/s1 KDBCNKHHBUKNRH-BNIKKZEQSA-N 50372853 CHEMBL270806 C-C chemokine receptor type 3 Homo sapiens 0.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372853&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455625 160851954 CHEMBL270806 ZINC29129507 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857831 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C InChI=1S/C27H34FN5O2/c1-19(30-27(35)31-24-7-3-6-22(17-24)26-29-12-14-32(26)2)15-25(34)33-13-4-5-21(18-33)16-20-8-10-23(28)11-9-20/h3,6-12,14,17,19,21,25,34H,4-5,13,15-16,18H2,1-2H3,(H2,30,31,35)/t19-,21+,25-/m1/s1 FLHWJOBAIDQWDE-FZOAFFARSA-N 50372838 CHEMBL429323 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372838&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455658 160851939 CHEMBL429323 ZINC29129588 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857832 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)C InChI=1S/C28H38FN7O2/c1-18(2)22-14-23(27-32-33-34-35(27)4)16-25(15-22)31-28(38)30-19(3)12-26(37)36-11-5-6-21(17-36)13-20-7-9-24(29)10-8-20/h7-10,14-16,18-19,21,26,37H,5-6,11-13,17H2,1-4H3,(H2,30,31,38)/t19-,21+,26-/m1/s1 VCIAJXLBWJRPBT-BNIKKZEQSA-N 50372854 CHEMBL257293 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372854&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455686 160851955 CHEMBL257293 ZINC29129671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857833 CCc1cc(NC(=O)N[C@H](C)C[C@@H](O)N2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O2/c1-4-19-14-22(26-31-32-33-34(26)3)16-24(15-19)30-27(37)29-18(2)12-25(36)35-11-5-6-21(17-35)13-20-7-9-23(28)10-8-20/h7-10,14-16,18,21,25,36H,4-6,11-13,17H2,1-3H3,(H2,29,30,37)/t18-,21+,25-/m1/s1 HRZQKGGVQGIRFQ-DHTSOJEISA-N 50372839 CHEMBL437031 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372839&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455711 160851940 CHEMBL437031 ZINC29129747 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857834 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(Br)cc(c1)-c1nnnn1C InChI=1S/C25H31BrFN7O2/c1-16(10-23(35)34-9-3-4-18(15-34)11-17-5-7-21(27)8-6-17)28-25(36)29-22-13-19(12-20(26)14-22)24-30-31-32-33(24)2/h5-8,12-14,16,18,23,35H,3-4,9-11,15H2,1-2H3,(H2,28,29,36)/t16-,18+,23-/m1/s1 YTOIIZAJOYVDMZ-WLENULPWSA-N 50372855 CHEMBL402983 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372855&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455745 160851956 CHEMBL402983 ZINC29129843 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857835 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(Br)cc(c1)-c1nnnn1C InChI=1S/C25H31BrFN7O/c1-17(9-11-34-10-3-4-19(16-34)12-18-5-7-22(27)8-6-18)28-25(35)29-23-14-20(13-21(26)15-23)24-30-31-32-33(24)2/h5-8,13-15,17,19H,3-4,9-12,16H2,1-2H3,(H2,28,29,35)/t17-,19+/m1/s1 CTZCYZCFMJXNPE-MJGOQNOKSA-N 50372856 CHEMBL403331 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372856&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455765 160851957 CHEMBL403331 ZINC29129923 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857836 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.3 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857837 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O4/c1-17(29-27(35)30-25-14-22(18(2)32)13-23(15-25)19(3)33)11-26(34)31-10-4-5-21(16-31)12-20-6-8-24(28)9-7-20/h6-9,13-15,17,21,26,34H,4-5,10-12,16H2,1-3H3,(H2,29,30,35)/t17-,21+,26-/m1/s1 BIPWHXLJDZRBGR-FQHLQPMKSA-N 50372857 CHEMBL256068 C-C chemokine receptor type 3 Homo sapiens 0.8 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372857&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455793 160851958 CHEMBL256068 ZINC29130000 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857838 C[C@@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18(12-14-33-13-4-5-20(17-33)15-19-8-10-22(26)11-9-19)27-25(34)28-23-7-3-6-21(16-23)24-29-30-31-32(24)2/h3,6-11,16,18,20H,4-5,12-15,17H2,1-2H3,(H2,27,28,34)/t18-,20-/m0/s1 RRHZFCXDULLQHS-ICSRJNTNSA-N 50372858 CHEMBL258323 C-C chemokine receptor type 3 Homo sapiens 4 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372858&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455792 160851959 CHEMBL258323 ZINC29129998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857839 CCC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C InChI=1S/C30H42FN7O2/c1-5-7-26(13-15-38-14-6-8-22(20-38)16-21-9-11-25(31)12-10-21)32-29(39)33-27-18-23(28-34-35-36-37(28)4)17-24(19-27)30(2,3)40/h9-12,17-19,22,26,40H,5-8,13-16,20H2,1-4H3,(H2,32,33,39)/t22-,26+/m0/s1 RECBRJKCPMUFRD-BKMJKUGQSA-N 50372859 CHEMBL257074 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372859&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455820 160851960 CHEMBL257074 ZINC29130085 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857840 CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C InChI=1S/C29H40FN7O2/c1-5-25(12-14-37-13-6-7-21(19-37)15-20-8-10-24(30)11-9-20)31-28(38)32-26-17-22(27-33-34-35-36(27)4)16-23(18-26)29(2,3)39/h8-11,16-18,21,25,39H,5-7,12-15,19H2,1-4H3,(H2,31,32,38)/t21-,25+/m0/s1 NQAYKLXCSBWKMD-SQJMNOBHSA-N 50372860 CHEMBL270146 C-C chemokine receptor type 3 Homo sapiens 2.4 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372860&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455845 160851961 CHEMBL270146 ZINC29130149 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857841 Fc1ccc(C[C@@H]2CCCN(CCCNC(=O)Nc3cc(cc(c3)-n3cccn3)-n3cccn3)C2)cc1 InChI=1S/C28H32FN7O/c29-24-8-6-22(7-9-24)17-23-5-1-13-34(21-23)14-2-10-30-28(37)33-25-18-26(35-15-3-11-31-35)20-27(19-25)36-16-4-12-32-36/h3-4,6-9,11-12,15-16,18-20,23H,1-2,5,10,13-14,17,21H2,(H2,30,33,37)/t23-/m0/s1 MJKZXBYUDVUDPD-QHCPKHFHSA-N 50372840 CHEMBL403839 C-C chemokine receptor type 3 Homo sapiens 1.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372840&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455847 160851941 CHEMBL403839 ZINC29130153 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857842 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)=O InChI=1S/C27H34FN7O2/c1-18(10-12-35-11-4-5-21(17-35)13-20-6-8-24(28)9-7-20)29-27(37)30-25-15-22(19(2)36)14-23(16-25)26-31-32-33-34(26)3/h6-9,14-16,18,21H,4-5,10-13,17H2,1-3H3,(H2,29,30,37)/t18-,21+/m1/s1 NXSAJAWQRXMZIP-NQIIRXRSSA-N 50372861 CHEMBL270582 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372861&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455869 160851962 CHEMBL270582 ZINC29130207 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857843 CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C26H32FN7O2/c1-18(35)21-14-22(25-30-31-32-33(25)2)16-24(15-21)29-26(36)28-10-4-12-34-11-3-5-20(17-34)13-19-6-8-23(27)9-7-19/h6-9,14-16,20H,3-5,10-13,17H2,1-2H3,(H2,28,29,36)/t20-/m0/s1 MRXDPGHAGCROAM-FQEVSTJZSA-N 50142451 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-[3-Acetyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295415 C-C chemokine receptor type 3 Homo sapiens 2.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142451&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289919 104031832 CHEMBL295415 ZINC29396122 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857844 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O3/c1-18(29-27(34)30-26-15-23(19(2)32)14-24(16-26)20(3)33)10-12-31-11-4-5-22(17-31)13-21-6-8-25(28)9-7-21/h6-9,14-16,18,22H,4-5,10-13,17H2,1-3H3,(H2,29,30,34)/t18-,22+/m1/s1 YMMAHNYFXNAREN-GCJKJVERSA-N 50372862 CHEMBL255398 C-C chemokine receptor type 3 Homo sapiens 2.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372862&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455459 160851963 CHEMBL255398 ZINC29129115 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857845 CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C26H32FN3O3/c1-18(31)22-14-23(19(2)32)16-25(15-22)29-26(33)28-10-4-12-30-11-3-5-21(17-30)13-20-6-8-24(27)9-7-20/h6-9,14-16,21H,3-5,10-13,17H2,1-2H3,(H2,28,29,33)/t21-/m0/s1 PSTIGTLOMGJZKB-NRFANRHFSA-N 50142468 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3,5-diacetylphenyl)urea::1-(3,5-Diacetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46404 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142468&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289926 104031849 CHEMBL46404 ZINC29399195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857846 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)C(O)=O)-c1nnnn1C InChI=1S/C29H38FN7O3/c1-19(11-13-37-12-5-6-21(18-37)14-20-7-9-24(30)10-8-20)31-28(40)32-25-16-22(26-33-34-35-36(26)4)15-23(17-25)29(2,3)27(38)39/h7-10,15-17,19,21H,5-6,11-14,18H2,1-4H3,(H,38,39)(H2,31,32,40)/t19-,21+/m1/s1 HJYDRMMVPRLQMJ-CTNGQTDRSA-N 50372863 CHEMBL404618 C-C chemokine receptor type 3 Homo sapiens 0.7 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372863&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455461 160851964 CHEMBL404618 ZINC29129117 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857847 Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 LCJFXGJVEJVLLZ-FQEVSTJZSA-N 50142444 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-methyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-methyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL444568 C-C chemokine receptor type 3 Homo sapiens 1.5 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289715 104031825 CHEMBL444568 ZINC29395019 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857848 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857849 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857850 Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1 DQSLLQXQXYFIRA-IBGZPJMESA-N 50142453 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43423 C-C chemokine receptor type 3 Homo sapiens 0.6 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289927 104031834 CHEMBL43423 ZINC29396014 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857851 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1cccn1)-n1cccn1 InChI=1S/C29H34FN7O2/c1-21(15-28(38)35-12-2-5-23(20-35)16-22-6-8-24(30)9-7-22)33-29(39)34-25-17-26(36-13-3-10-31-36)19-27(18-25)37-14-4-11-32-37/h3-4,6-11,13-14,17-19,21,23,28,38H,2,5,12,15-16,20H2,1H3,(H2,33,34,39)/t21-,23+,28-/m1/s1 MRKMZVYMRPCVIP-ZLIGTFTASA-N 50372826 CHEMBL401879 C-C chemokine receptor type 3 Homo sapiens 0.05 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372826&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455683 160851927 CHEMBL401879 ZINC29129667 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857852 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)C InChI=1S/C28H38FN7O2/c1-18(2)22-14-23(27-32-33-34-35(27)4)16-25(15-22)31-28(38)30-19(3)12-26(37)36-11-5-6-21(17-36)13-20-7-9-24(29)10-8-20/h7-10,14-16,18-19,21,26,37H,5-6,11-13,17H2,1-4H3,(H2,30,31,38)/t19-,21+,26-/m1/s1 VCIAJXLBWJRPBT-BNIKKZEQSA-N 50372854 CHEMBL257293 C-C chemokine receptor type 3 Homo sapiens 0.02 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372854&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455686 160851955 CHEMBL257293 ZINC29129671 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857853 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(Br)cc(c1)-c1nnnn1C InChI=1S/C25H31BrFN7O2/c1-16(10-23(35)34-9-3-4-18(15-34)11-17-5-7-21(27)8-6-17)28-25(36)29-22-13-19(12-20(26)14-22)24-30-31-32-33(24)2/h5-8,12-14,16,18,23,35H,3-4,9-11,15H2,1-2H3,(H2,28,29,36)/t16-,18+,23-/m1/s1 YTOIIZAJOYVDMZ-WLENULPWSA-N 50372855 CHEMBL402983 C-C chemokine receptor type 3 Homo sapiens 0.05 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372855&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455745 160851956 CHEMBL402983 ZINC29129843 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857854 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.04 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857855 C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O4/c1-17(29-27(35)30-25-14-22(18(2)32)13-23(15-25)19(3)33)11-26(34)31-10-4-5-21(16-31)12-20-6-8-24(28)9-7-20/h6-9,13-15,17,21,26,34H,4-5,10-12,16H2,1-3H3,(H2,29,30,35)/t17-,21+,26-/m1/s1 BIPWHXLJDZRBGR-FQHLQPMKSA-N 50372857 CHEMBL256068 C-C chemokine receptor type 3 Homo sapiens 0.06 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372857&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455793 160851958 CHEMBL256068 ZINC29130000 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857856 C[C@@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18(12-14-33-13-4-5-20(17-33)15-19-8-10-22(26)11-9-19)27-25(34)28-23-7-3-6-21(16-23)24-29-30-31-32(24)2/h3,6-11,16,18,20H,4-5,12-15,17H2,1-2H3,(H2,27,28,34)/t18-,20-/m0/s1 RRHZFCXDULLQHS-ICSRJNTNSA-N 50372858 CHEMBL258323 C-C chemokine receptor type 3 Homo sapiens >1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372858&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455792 160851959 CHEMBL258323 ZINC29129998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857857 CCC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C InChI=1S/C30H42FN7O2/c1-5-7-26(13-15-38-14-6-8-22(20-38)16-21-9-11-25(31)12-10-21)32-29(39)33-27-18-23(28-34-35-36-37(28)4)17-24(19-27)30(2,3)40/h9-12,17-19,22,26,40H,5-8,13-16,20H2,1-4H3,(H2,32,33,39)/t22-,26+/m0/s1 RECBRJKCPMUFRD-BKMJKUGQSA-N 50372859 CHEMBL257074 C-C chemokine receptor type 3 Homo sapiens 0.011 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372859&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455820 160851960 CHEMBL257074 ZINC29130085 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857858 CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C InChI=1S/C29H40FN7O2/c1-5-25(12-14-37-13-6-7-21(19-37)15-20-8-10-24(30)11-9-20)31-28(38)32-26-17-22(27-33-34-35-36(27)4)16-23(18-26)29(2,3)39/h8-11,16-18,21,25,39H,5-7,12-15,19H2,1-4H3,(H2,31,32,38)/t21-,25+/m0/s1 NQAYKLXCSBWKMD-SQJMNOBHSA-N 50372860 CHEMBL270146 C-C chemokine receptor type 3 Homo sapiens 0.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372860&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455845 160851961 CHEMBL270146 ZINC29130149 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857859 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-n1cccn1)-n1cccn1 InChI=1S/C29H34FN7O/c1-22(10-16-35-13-2-5-24(21-35)17-23-6-8-25(30)9-7-23)33-29(38)34-26-18-27(36-14-3-11-31-36)20-28(19-26)37-15-4-12-32-37/h3-4,6-9,11-12,14-15,18-20,22,24H,2,5,10,13,16-17,21H2,1H3,(H2,33,34,38)/t22-,24+/m1/s1 USWHNYCYCAKUDH-VWNXMTODSA-N 50372830 CHEMBL270147 C-C chemokine receptor type 3 Homo sapiens 0.1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372830&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455846 160851931 CHEMBL270147 ZINC29130151 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857860 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)=O InChI=1S/C27H34FN7O2/c1-18(10-12-35-11-4-5-21(17-35)13-20-6-8-24(28)9-7-20)29-27(37)30-25-15-22(19(2)36)14-23(16-25)26-31-32-33-34(26)3/h6-9,14-16,18,21H,4-5,10-13,17H2,1-3H3,(H2,29,30,37)/t18-,21+/m1/s1 NXSAJAWQRXMZIP-NQIIRXRSSA-N 50372861 CHEMBL270582 C-C chemokine receptor type 3 Homo sapiens 0.02 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372861&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455869 160851962 CHEMBL270582 ZINC29130207 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857861 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O3/c1-18(29-27(34)30-26-15-23(19(2)32)14-24(16-26)20(3)33)10-12-31-11-4-5-22(17-31)13-21-6-8-25(28)9-7-21/h6-9,14-16,18,22H,4-5,10-13,17H2,1-3H3,(H2,29,30,34)/t18-,22+/m1/s1 YMMAHNYFXNAREN-GCJKJVERSA-N 50372862 CHEMBL255398 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372862&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455459 160851963 CHEMBL255398 ZINC29129115 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857862 CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)=O InChI=1S/C26H32FN3O3/c1-18(31)22-14-23(19(2)32)16-25(15-22)29-26(33)28-10-4-12-30-11-3-5-21(17-30)13-20-6-8-24(27)9-7-20/h6-9,14-16,21H,3-5,10-13,17H2,1-2H3,(H2,28,29,33)/t21-/m0/s1 PSTIGTLOMGJZKB-NRFANRHFSA-N 50142468 (S)-1-(3-(3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3,5-diacetylphenyl)urea::1-(3,5-Diacetyl-phenyl)-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL46404 C-C chemokine receptor type 3 Homo sapiens 3 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142468&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289926 104031849 CHEMBL46404 ZINC29399195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857863 Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O InChI=1S/C28H36FN7O3/c1-28(2,26(37)38)22-15-21(25-32-33-34-35(25)3)16-24(17-22)31-27(39)30-11-5-13-36-12-4-6-20(18-36)14-19-7-9-23(29)10-8-19/h7-10,15-17,20H,4-6,11-14,18H2,1-3H3,(H,37,38)(H2,30,31,39)/t20-/m0/s1 OMYKGVIQNBTKOU-FQEVSTJZSA-N 50372832 CHEMBL272068 C-C chemokine receptor type 3 Homo sapiens 0.304 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372832&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455483 160851933 CHEMBL272068 ZINC29129156 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857864 C[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)-c1nnnn1C)C(C)C InChI=1S/C28H38FN7O/c1-19(2)23-15-24(27-32-33-34-35(27)4)17-26(16-23)31-28(37)30-20(3)11-13-36-12-5-6-22(18-36)14-21-7-9-25(29)10-8-21/h7-10,15-17,19-20,22H,5-6,11-14,18H2,1-4H3,(H2,30,31,37)/t20-,22+/m1/s1 CAFBEDWUSCRFBS-IRLDBZIGSA-N 50372842 CHEMBL404122 C-C chemokine receptor type 3 Homo sapiens 0.021 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372842&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455485 160851943 CHEMBL404122 ZINC29129159 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857865 CCc1cc(NC(=O)N[C@H](C)CCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C27H36FN7O/c1-4-20-15-23(26-31-32-33-34(26)3)17-25(16-20)30-27(36)29-19(2)11-13-35-12-5-6-22(18-35)14-21-7-9-24(28)10-8-21/h7-10,15-17,19,22H,4-6,11-14,18H2,1-3H3,(H2,29,30,36)/t19-,22+/m1/s1 IQUQYZRIYXKKDB-KNQAVFIVSA-N 50372833 CHEMBL427728 C-C chemokine receptor type 3 Homo sapiens 0.02 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372833&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455509 160851934 CHEMBL427728 ZINC29129200 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857866 Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1 LCJFXGJVEJVLLZ-FQEVSTJZSA-N 50142444 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-methyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-methyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL444568 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142444&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289715 104031825 CHEMBL444568 ZINC29395019 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857867 Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN7O/c1-35-27(32-33-34-35)22-8-4-9-25(17-22)30-28(37)31-26-10-3-2-7-23(26)19-36-15-5-6-21(18-36)16-20-11-13-24(29)14-12-20/h4,8-9,11-14,17,21,23,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,37)/t21-,23-,26+/m0/s1 HEXTXRMVMKIBQR-RZPFDVGOSA-N 50163634 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL363840 C-C chemokine receptor type 3 Homo sapiens 0.01 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163634&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11272103 104049617 CHEMBL363840 ZINC13613369 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857868 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.034 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857869 Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1 DQSLLQXQXYFIRA-IBGZPJMESA-N 50142453 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43423 C-C chemokine receptor type 3 Homo sapiens 3.2 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142453&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44289927 104031834 CHEMBL43423 ZINC29396014 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857912 C[C@@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)=O)C(C)=O InChI=1S/C27H34FN3O3/c1-18(29-27(34)30-26-15-23(19(2)32)14-24(16-26)20(3)33)10-12-31-11-4-5-22(17-31)13-21-6-8-25(28)9-7-21/h6-9,14-16,18,22H,4-5,10-13,17H2,1-3H3,(H2,29,30,34)/t18-,22-/m0/s1 YMMAHNYFXNAREN-AVRDEDQJSA-N 50372831 CHEMBL404202 C-C chemokine receptor type 3 Homo sapiens 60 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372831&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44455872 160851932 CHEMBL404202 ZINC29130212 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50857913 C[C@@H](NC(=O)Nc1cccc(c1)-c1nnnn1C)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1 InChI=1S/C25H32FN7O2/c1-17(27-25(35)28-22-7-3-6-20(14-22)24-29-30-31-32(24)2)23(34)16-33-12-4-5-19(15-33)13-18-8-10-21(26)11-9-18/h3,6-11,14,17,19,23,34H,4-5,12-13,15-16H2,1-2H3,(H2,27,28,35)/t17-,19+,23+/m1/s1 JTVSGNGYUGCQJP-FHJLPGHOSA-N 50231358 1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl)-3-hydroxybutan-2-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-2-hydroxy-1-methyl-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::BMS-639623::CHEMBL399495 C-C chemokine receptor type 3 Homo sapiens 0.87 ChEMBL 10.1016/j.bmcl.2007.11.067 10.7270/Q2057GS3 18096386 Santella, JB; Gardner, DS; Yao, W; Shi, C; Reddy, P; Tebben, AJ; DeLucca, GV; Wacker, DA; Watson, PS; Welch, PK; Wadman, EA; Davies, P; Solomon, KA; Graden, DM; Yeleswaram, S; Mandlekar, S; Kariv, I; Decicco, CP; Ko, SS; Carter, PH; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231358&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10050884 104055089 CHEMBL399495 ZINC29039045 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945162 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 InChI=1S/C31H29FN2O/c32-25-13-12-23-16-21(10-11-24(23)17-25)20-34-27-14-15-28(34)19-26(18-27)33-31(35)30-9-5-4-8-29(30)22-6-2-1-3-7-22/h1-13,16-17,26-28H,14-15,18-20H2,(H,33,35)/t27-,28-/m1/s1 DBWKEBCQXCVXLS-VSGBNLITSA-N 50387642 CHEMBL2057491 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387642&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70696744 160866725 CHEMBL2057491 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945163 Fc1ccc2C(=O)N(CCc2c1)C(=O)NCCCN1CCC(CC1)C(c1ccccc1)c1ccccc1 InChI=1S/C31H34FN3O2/c32-27-12-13-28-26(22-27)16-21-35(30(28)36)31(37)33-17-7-18-34-19-14-25(15-20-34)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-13,22,25,29H,7,14-21H2,(H,33,37) CKELZMRWTINUSM-UHFFFAOYSA-N 50387643 CHEMBL2057490 C-C chemokine receptor type 3 Homo sapiens 190 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387643&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70692659 160866726 CHEMBL2057490 ZINC84723899 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945164 Cc1nnc2n(CCCN3CCN(CC3)C(c3ccccc3)c3ccccc3)c(=O)c3ccccc3n12 InChI=1S/C30H32N6O/c1-23-31-32-30-35(29(37)26-15-8-9-16-27(26)36(23)30)18-10-17-33-19-21-34(22-20-33)28(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16,28H,10,17-22H2,1H3 IHTWZHOQGBESPE-UHFFFAOYSA-N 50387644 CHEMBL2057489 C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387644&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9826988 160866727 CHEMBL2057489 ZINC22036228 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945165 Fc1ccc2CN(CCc2c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C28H29F2N3O/c29-23-5-3-19-11-18(1-2-20(19)12-23)16-33-26-7-8-27(33)15-25(14-26)31-28(34)32-10-9-21-13-24(30)6-4-22(21)17-32/h1-6,11-13,25-27H,7-10,14-17H2,(H,31,34)/t26-,27-/m1/s1 IROXSEALRLOTNW-KAYWLYCHSA-N 50387645 CHEMBL2057746 C-C chemokine receptor type 3 Homo sapiens 780 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387645&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70684221 160866728 CHEMBL2057746 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945166 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC4(CC3)N(CNC4=O)c3ccccc3)ccc2c1 InChI=1S/C32H36FN5O2/c33-25-9-8-23-16-22(6-7-24(23)17-25)20-37-28-10-11-29(37)19-26(18-28)35-31(40)36-14-12-32(13-15-36)30(39)34-21-38(32)27-4-2-1-3-5-27/h1-9,16-17,26,28-29H,10-15,18-21H2,(H,34,39)(H,35,40)/t28-,29-/m1/s1 SKFJGFOXJOWIJE-FQLXRVMXSA-N 50387646 CHEMBL2057747 C-C chemokine receptor type 3 Homo sapiens 59 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387646&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70690517 160866729 CHEMBL2057747 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945167 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4ccccc4[nH]c3=O)ccc2c1 InChI=1S/C31H34FN5O2/c32-23-8-7-21-15-20(5-6-22(21)16-23)19-36-26-9-10-27(36)18-24(17-26)33-30(38)35-13-11-25(12-14-35)37-29-4-2-1-3-28(29)34-31(37)39/h1-8,15-16,24-27H,9-14,17-19H2,(H,33,38)(H,34,39)/t26-,27-/m1/s1 HWVQJBGFQNRSON-KAYWLYCHSA-N 50387647 CHEMBL2057749 C-C chemokine receptor type 3 Homo sapiens 52 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387647&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70690519 160866730 CHEMBL2057749 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945168 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC(CC3)n3c4cccc(F)c4[nH]c3=O)ccc2c1 InChI=1S/C31H33F2N5O2/c32-22-7-6-20-14-19(4-5-21(20)15-22)18-37-25-8-9-26(37)17-23(16-25)34-30(39)36-12-10-24(11-13-36)38-28-3-1-2-27(33)29(28)35-31(38)40/h1-7,14-15,23-26H,8-13,16-18H2,(H,34,39)(H,35,40)/t25-,26-/m1/s1 YYRVXHGXCWPYBK-CLJLJLNGSA-N 50387648 CHEMBL2057750 C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387648&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70682098 160866731 CHEMBL2057750 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945169 Nc1ccc2n(C3CCN(CC3)C(=O)NC3C[C@H]4CC[C@H](C3)N4Cc3ccc4cc(F)ccc4c3)c(=O)[nH]c2c1 InChI=1S/C31H35FN6O2/c32-22-4-3-20-13-19(1-2-21(20)14-22)18-37-26-6-7-27(37)17-24(16-26)34-30(39)36-11-9-25(10-12-36)38-29-8-5-23(33)15-28(29)35-31(38)40/h1-5,8,13-15,24-27H,6-7,9-12,16-18,33H2,(H,34,39)(H,35,40)/t26-,27-/m1/s1 IUOYHNSIVPLIQB-KAYWLYCHSA-N 50387649 CHEMBL2057751 C-C chemokine receptor type 3 Homo sapiens 8 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387649&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70696751 160866732 CHEMBL2057751 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945170 Fc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H34F2N4O2/c32-25-7-4-22(5-8-25)30(38)35-12-1-13-36(15-14-35)31(39)34-27-18-28-10-11-29(19-27)37(28)20-21-2-3-24-17-26(33)9-6-23(24)16-21/h2-9,16-17,27-29H,1,10-15,18-20H2,(H,34,39)/t28-,29-/m1/s1 JGBAXYKSBBPDHG-FQLXRVMXSA-N 50387650 CHEMBL2057752 C-C chemokine receptor type 3 Homo sapiens 310 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387650&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70682099 160866733 CHEMBL2057752 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945171 Nc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H36FN5O2/c32-25-7-4-23-16-21(2-3-24(23)17-25)20-37-28-10-11-29(37)19-27(18-28)34-31(39)36-13-1-12-35(14-15-36)30(38)22-5-8-26(33)9-6-22/h2-9,16-17,27-29H,1,10-15,18-20,33H2,(H,34,39)/t28-,29-/m1/s1 BCOXRTSTZIXWPV-FQLXRVMXSA-N 50387651 CHEMBL2057753 C-C chemokine receptor type 3 Homo sapiens 380 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387651&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70686357 160866734 CHEMBL2057753 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945172 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)C(=O)c3c(Cl)cccc3Cl)ccc2c1 InChI=1S/C31H33Cl2FN4O2/c32-27-3-1-4-28(33)29(27)30(39)36-11-2-12-37(14-13-36)31(40)35-24-17-25-9-10-26(18-24)38(25)19-20-5-6-22-16-23(34)8-7-21(22)15-20/h1,3-8,15-16,24-26H,2,9-14,17-19H2,(H,35,40)/t25-,26-/m1/s1 GFBZENKRVCVGSC-CLJLJLNGSA-N 50387652 CHEMBL2057754 C-C chemokine receptor type 3 Homo sapiens 62 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387652&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70694701 160866735 CHEMBL2057754 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945173 Oc1cccc(F)c1C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H34F2N4O3/c32-23-8-7-21-15-20(5-6-22(21)16-23)19-37-25-9-10-26(37)18-24(17-25)34-31(40)36-12-2-11-35(13-14-36)30(39)29-27(33)3-1-4-28(29)38/h1,3-8,15-16,24-26,38H,2,9-14,17-19H2,(H,34,40)/t25-,26-/m1/s1 IGAZFIPCMKGSBM-CLJLJLNGSA-N 50387653 CHEMBL2057755 C-C chemokine receptor type 3 Homo sapiens 51 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387653&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70694702 160866736 CHEMBL2057755 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945174 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(Cc4c(Cl)cccc4Cl)CC3)ccc2c1 InChI=1S/C31H35Cl2FN4O/c32-29-3-1-4-30(33)28(29)20-36-11-2-12-37(14-13-36)31(39)35-25-17-26-9-10-27(18-25)38(26)19-21-5-6-23-16-24(34)8-7-22(23)15-21/h1,3-8,15-16,25-27H,2,9-14,17-20H2,(H,35,39)/t26-,27-/m1/s1 SNGKQWWYJZLZHM-KAYWLYCHSA-N 50387654 CHEMBL2057756 C-C chemokine receptor type 3 Homo sapiens 18 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387654&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70688459 160866737 CHEMBL2057756 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945175 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCN(CC3)C(=O)c3c(Cl)cccc3Cl)ccc2c1 InChI=1S/C30H31Cl2FN4O2/c31-26-2-1-3-27(32)28(26)29(38)35-10-12-36(13-11-35)30(39)34-23-16-24-8-9-25(17-23)37(24)18-19-4-5-21-15-22(33)7-6-20(21)14-19/h1-7,14-15,23-25H,8-13,16-18H2,(H,34,39)/t24-,25-/m1/s1 JKTDSWBPQGRDKI-JWQCQUIFSA-N 50387655 CHEMBL2057757 C-C chemokine receptor type 3 Homo sapiens 1600 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387655&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70682100 160866738 CHEMBL2057757 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945176 Oc1ccc(cc1)C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H35FN4O3/c32-25-7-4-23-16-21(2-3-24(23)17-25)20-36-27-8-9-28(36)19-26(18-27)33-31(39)35-13-1-12-34(14-15-35)30(38)22-5-10-29(37)11-6-22/h2-7,10-11,16-17,26-28,37H,1,8-9,12-15,18-20H2,(H,33,39)/t27-,28-/m1/s1 WCCWAIPYJIMANI-VSGBNLITSA-N 50387656 CHEMBL2057758 C-C chemokine receptor type 3 Homo sapiens 440 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387656&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70682101 160866739 CHEMBL2057758 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945177 Oc1ccccc1C(=O)N1CCCN(CC1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H35FN4O3/c32-24-9-8-22-16-21(6-7-23(22)17-24)20-36-26-10-11-27(36)19-25(18-26)33-31(39)35-13-3-12-34(14-15-35)30(38)28-4-1-2-5-29(28)37/h1-2,4-9,16-17,25-27,37H,3,10-15,18-20H2,(H,33,39)/t26-,27-/m1/s1 LVDMLESNCDNOKN-KAYWLYCHSA-N 50387657 CHEMBL2057759 C-C chemokine receptor type 3 Homo sapiens 63 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387657&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70696752 160866740 CHEMBL2057759 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945178 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)C(=O)C3(CC3)c3ccccc3)ccc2c1 InChI=1S/C34H39FN4O2/c35-28-10-9-25-19-24(7-8-26(25)20-28)23-39-30-11-12-31(39)22-29(21-30)36-33(41)38-16-4-15-37(17-18-38)32(40)34(13-14-34)27-5-2-1-3-6-27/h1-3,5-10,19-20,29-31H,4,11-18,21-23H2,(H,36,41)/t30-,31-/m1/s1 ALNPYJIMVMNPSZ-FIRIVFDPSA-N 50387658 CHEMBL2057760 C-C chemokine receptor type 3 Homo sapiens 45 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387658&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70692666 160866741 CHEMBL2057760 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945179 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCCN(CC3)S(=O)(=O)c3ccccc3)ccc2c1 InChI=1S/C30H35FN4O3S/c31-25-10-9-23-17-22(7-8-24(23)18-25)21-35-27-11-12-28(35)20-26(19-27)32-30(36)33-13-4-14-34(16-15-33)39(37,38)29-5-2-1-3-6-29/h1-3,5-10,17-18,26-28H,4,11-16,19-21H2,(H,32,36)/t27-,28-/m1/s1 VCICQZKRFMYLAM-VSGBNLITSA-N 50387659 CHEMBL2057761 C-C chemokine receptor type 3 Homo sapiens 56 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387659&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70690520 160866742 CHEMBL2057761 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945180 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3)ccc2c1 InChI=1S/C30H33FN4O2/c31-23-11-10-21-15-20(8-9-22(21)16-23)19-35-26-12-13-27(35)18-25(17-26)33-30(37)34-14-4-7-28(34)29(36)32-24-5-2-1-3-6-24/h1-3,5-6,8-11,15-16,25-28H,4,7,12-14,17-19H2,(H,32,36)(H,33,37)/t26-,27-,28+/m1/s1 IEWKUVQUVKECHP-FCEKVYKBSA-N 50387660 CHEMBL2057762 C-C chemokine receptor type 3 Homo sapiens 240 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387660&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70696753 160866743 CHEMBL2057762 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945181 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3Br)ccc2c1 InChI=1S/C30H32BrFN4O2/c31-26-4-1-2-5-27(26)34-29(37)28-6-3-13-35(28)30(38)33-23-16-24-11-12-25(17-23)36(24)18-19-7-8-21-15-22(32)10-9-20(21)14-19/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 VNAWYIZKRVILEN-SKVJQKLOSA-N 50387661 CHEMBL2057763 C-C chemokine receptor type 3 Homo sapiens 13 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387661&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70686358 160866744 CHEMBL2057763 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945182 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3cccc(Br)c3)ccc2c1 InChI=1S/C30H32BrFN4O2/c31-22-3-1-4-24(15-22)33-29(37)28-5-2-12-35(28)30(38)34-25-16-26-10-11-27(17-25)36(26)18-19-6-7-21-14-23(32)9-8-20(21)13-19/h1,3-4,6-9,13-15,25-28H,2,5,10-12,16-18H2,(H,33,37)(H,34,38)/t26-,27-,28+/m1/s1 DEXIKTIXCRCWFC-FCEKVYKBSA-N 50387662 CHEMBL2057764 C-C chemokine receptor type 3 Homo sapiens 110 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387662&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70694703 160866745 CHEMBL2057764 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945183 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccc(Br)cc3)ccc2c1 InChI=1S/C30H32BrFN4O2/c31-22-6-9-24(10-7-22)33-29(37)28-2-1-13-35(28)30(38)34-25-16-26-11-12-27(17-25)36(26)18-19-3-4-21-15-23(32)8-5-20(21)14-19/h3-10,14-15,25-28H,1-2,11-13,16-18H2,(H,33,37)(H,34,38)/t26-,27-,28+/m1/s1 UHTQTGHXKJNPMK-FCEKVYKBSA-N 50387663 CHEMBL2057765 C-C chemokine receptor type 3 Homo sapiens 920 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387663&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70688460 160866746 CHEMBL2057765 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945184 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3F)ccc2c1 InChI=1S/C30H32F2N4O2/c31-22-10-9-20-14-19(7-8-21(20)15-22)18-36-24-11-12-25(36)17-23(16-24)33-30(38)35-13-3-6-28(35)29(37)34-27-5-2-1-4-26(27)32/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 SODXMFCMLOOZQF-SKVJQKLOSA-N 50387664 CHEMBL2057766 C-C chemokine receptor type 3 Homo sapiens 13 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387664&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70682102 160866747 CHEMBL2057766 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945185 Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3Cl)ccc2c1 InChI=1S/C30H32ClFN4O2/c31-26-4-1-2-5-27(26)34-29(37)28-6-3-13-35(28)30(38)33-23-16-24-11-12-25(17-23)36(24)18-19-7-8-21-15-22(32)10-9-20(21)14-19/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1 WVSKHPCDRYCNDK-SKVJQKLOSA-N 50387665 CHEMBL2058070 C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387665&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70688469 160866748 CHEMBL2058070 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945186 COc1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C31H35FN4O3/c1-39-29-7-3-2-5-27(29)34-30(37)28-6-4-14-35(28)31(38)33-24-17-25-12-13-26(18-24)36(25)19-20-8-9-22-16-23(32)11-10-21(22)15-20/h2-3,5,7-11,15-16,24-26,28H,4,6,12-14,17-19H2,1H3,(H,33,38)(H,34,37)/t25-,26-,28+/m1/s1 QNOTUWLYCQMBHP-GTNKKZTPSA-N 50387666 CHEMBL2058072 C-C chemokine receptor type 3 Homo sapiens 31 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387666&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70684230 160866749 CHEMBL2058072 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945187 CC(C)c1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C33H39FN4O2/c1-21(2)29-6-3-4-7-30(29)36-32(39)31-8-5-15-37(31)33(40)35-26-18-27-13-14-28(19-26)38(27)20-22-9-10-24-17-25(34)12-11-23(24)16-22/h3-4,6-7,9-12,16-17,21,26-28,31H,5,8,13-15,18-20H2,1-2H3,(H,35,40)(H,36,39)/t27-,28-,31+/m1/s1 YDCIEGOZQVNQNV-WUNLWTINSA-N 50387667 CHEMBL2058073 C-C chemokine receptor type 3 Homo sapiens 30 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387667&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70688470 160866750 CHEMBL2058073 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945188 CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccc3cc(F)ccc3c2)C1=O InChI=1S/C33H38FN5O2/c1-36-22-39(28-5-3-2-4-6-28)33(31(36)40)13-15-37(16-14-33)32(41)35-27-19-29-11-12-30(20-27)38(29)21-23-7-8-25-18-26(34)10-9-24(25)17-23/h2-10,17-18,27,29-30H,11-16,19-22H2,1H3,(H,35,41)/t29-,30-/m1/s1 MBBCONCPLJSTET-LOYHVIPDSA-N 50387668 CHEMBL2057748 C-C chemokine receptor type 3 Homo sapiens 360 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387668&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70690518 160866751 CHEMBL2057748 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50945189 [O-][N+](=O)c1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 InChI=1S/C30H32FN5O4/c31-22-10-9-20-14-19(7-8-21(20)15-22)18-35-24-11-12-25(35)17-23(16-24)32-30(38)34-13-3-6-28(34)29(37)33-26-4-1-2-5-27(26)36(39)40/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,32,38)(H,33,37)/t24-,25-,28+/m1/s1 DVYBRPLQGQOYSM-SKVJQKLOSA-N 50387669 CHEMBL2058071 C-C chemokine receptor type 3 Homo sapiens 4.9 ChEMBL 10.1016/j.bmcl.2012.06.042 10.7270/Q2057H06 22749826 Nitta, A; Iura, Y; Tomioka, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387669&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70696765 160866752 CHEMBL2058071 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961511 OCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H26FN3O3/c25-20-8-7-18-13-17(5-6-19(18)14-20)15-28-10-9-21(16-28)26-24(30)27-22-3-1-2-4-23(22)31-12-11-29/h1-8,13-14,21,29H,9-12,15-16H2,(H2,26,27,30)/t21-/m1/s1 SURDXQHAGDOKKM-OAQYLSRUSA-N 50394470 CHEMBL2160099 C-C chemokine receptor type 3 Homo sapiens 0.87 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460523 163343494 CHEMBL2160099 ZINC38460356 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961512 NC(=O)COc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H25FN4O3/c25-19-8-7-17-11-16(5-6-18(17)12-19)13-29-10-9-20(14-29)27-24(31)28-21-3-1-2-4-22(21)32-15-23(26)30/h1-8,11-12,20H,9-10,13-15H2,(H2,26,30)(H2,27,28,31)/t20-/m1/s1 VMSJYRKDXBWCBY-HXUWFJFHSA-N 50394471 CHEMBL2160106 C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394471&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453336 163343495 CHEMBL2160106 ZINC95578970 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961513 CN(C)CCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C26H31FN4O2/c1-30(2)13-14-33-25-6-4-3-5-24(25)29-26(32)28-23-11-12-31(18-23)17-19-7-8-21-16-22(27)10-9-20(21)15-19/h3-10,15-16,23H,11-14,17-18H2,1-2H3,(H2,28,29,32)/t23-/m1/s1 RPBFMJYGFVCQFP-HSZRJFAPSA-N 50394472 CHEMBL2160105 C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394472&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71455044 163343496 CHEMBL2160105 ZINC95577306 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961514 OCCOc1cccc(NC(=O)N[C@@H]2CCN(Cc3ccc4cc(F)ccc4c3)C2)c1 InChI=1S/C24H26FN3O3/c25-20-7-6-18-12-17(4-5-19(18)13-20)15-28-9-8-22(16-28)27-24(30)26-21-2-1-3-23(14-21)31-11-10-29/h1-7,12-14,22,29H,8-11,15-16H2,(H2,26,27,30)/t22-/m1/s1 WLOACWIOQWNDSJ-JOCHJYFZSA-N 50394473 CHEMBL2160104 C-C chemokine receptor type 3 Homo sapiens 190 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394473&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10194663 163343497 CHEMBL2160104 ZINC95577370 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961515 OCCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C25H28FN3O3/c26-21-9-8-19-14-18(6-7-20(19)15-21)16-29-11-10-22(17-29)27-25(31)28-23-4-1-2-5-24(23)32-13-3-12-30/h1-2,4-9,14-15,22,30H,3,10-13,16-17H2,(H2,27,28,31)/t22-/m1/s1 YYHNQEPJISUEBC-JOCHJYFZSA-N 50394474 CHEMBL2160103 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394474&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453335 163343498 CHEMBL2160103 ZINC34376363 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961516 OCCOCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C25H28FN3O3/c26-22-8-7-19-13-18(5-6-20(19)14-22)15-29-10-9-23(16-29)27-25(31)28-24-4-2-1-3-21(24)17-32-12-11-30/h1-8,13-14,23,30H,9-12,15-17H2,(H2,27,28,31)/t23-/m1/s1 QBTMCFACBFWXTL-HSZRJFAPSA-N 50394475 CHEMBL2160102 C-C chemokine receptor type 3 Homo sapiens 110 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394475&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449694 163343499 CHEMBL2160102 ZINC95574961 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961517 COCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C25H28FN3O3/c1-31-12-13-32-24-5-3-2-4-23(24)28-25(30)27-22-10-11-29(17-22)16-18-6-7-20-15-21(26)9-8-19(20)14-18/h2-9,14-15,22H,10-13,16-17H2,1H3,(H2,27,28,30)/t22-/m1/s1 KEWOMAXHGIMGIW-JOCHJYFZSA-N 50394476 CHEMBL2160101 C-C chemokine receptor type 3 Homo sapiens 71 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394476&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71456840 163343500 CHEMBL2160101 ZINC95576733 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961518 OCCOCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C26H30FN3O4/c27-22-8-7-20-15-19(5-6-21(20)16-22)17-30-10-9-23(18-30)28-26(32)29-24-3-1-2-4-25(24)34-14-13-33-12-11-31/h1-8,15-16,23,31H,9-14,17-18H2,(H2,28,29,32)/t23-/m1/s1 PSDYBCJONFQUBE-HSZRJFAPSA-N 50394477 CHEMBL2160100 C-C chemokine receptor type 3 Homo sapiens 28 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394477&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71456839 163343501 CHEMBL2160100 ZINC95572584 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961519 OCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H26FN3O3/c25-20-8-7-18-13-17(5-6-19(18)14-20)15-28-10-9-21(16-28)26-24(30)27-22-3-1-2-4-23(22)31-12-11-29/h1-8,13-14,21,29H,9-12,15-16H2,(H2,26,27,30)/t21-/m1/s1 SURDXQHAGDOKKM-OAQYLSRUSA-N 50394470 CHEMBL2160099 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460523 163343494 CHEMBL2160099 ZINC38460356 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961520 OCCCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C25H28FN3O2/c26-22-10-9-20-14-18(7-8-21(20)15-22)16-29-12-11-23(17-29)27-25(31)28-24-6-2-1-4-19(24)5-3-13-30/h1-2,4,6-10,14-15,23,30H,3,5,11-13,16-17H2,(H2,27,28,31)/t23-/m1/s1 YYQTWWJPPNVDHY-HSZRJFAPSA-N 50394478 CHEMBL2160098 C-C chemokine receptor type 3 Homo sapiens 51 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394478&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462226 163343502 CHEMBL2160098 ZINC95574960 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961521 COCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H26FN3O2/c1-30-16-20-4-2-3-5-23(20)27-24(29)26-22-10-11-28(15-22)14-17-6-7-19-13-21(25)9-8-18(19)12-17/h2-9,12-13,22H,10-11,14-16H2,1H3,(H2,26,27,29)/t22-/m1/s1 MQNDNJDYZVJFQY-JOCHJYFZSA-N 50394479 CHEMBL2160097 C-C chemokine receptor type 3 Homo sapiens 23 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453334 163343503 CHEMBL2160097 ZINC95574992 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961522 CN(C)C(=O)COc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C26H29FN4O3/c1-30(2)25(32)17-34-24-6-4-3-5-23(24)29-26(33)28-22-11-12-31(16-22)15-18-7-8-20-14-21(27)10-9-19(20)13-18/h3-10,13-14,22H,11-12,15-17H2,1-2H3,(H2,28,29,33)/t22-/m1/s1 LNCPMCGJXXEQPA-JOCHJYFZSA-N 50394480 CHEMBL2159869 C-C chemokine receptor type 3 Homo sapiens 24 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394480&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71455029 163343504 CHEMBL2159869 ZINC95572015 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961523 OCCOc1ccc(NC(=O)N[C@@H]2CCN(Cc3ccc4cc(F)ccc4c3)C2)cc1 InChI=1S/C24H26FN3O3/c25-20-4-3-18-13-17(1-2-19(18)14-20)15-28-10-9-22(16-28)27-24(30)26-21-5-7-23(8-6-21)31-12-11-29/h1-8,13-14,22,29H,9-12,15-16H2,(H2,26,27,30)/t22-/m1/s1 WVPFINARMGFUER-JOCHJYFZSA-N 50394481 CHEMBL2159868 C-C chemokine receptor type 3 Homo sapiens 12 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394481&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71458677 163343505 CHEMBL2159868 ZINC95578478 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961524 OCCCCOc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C26H30FN3O3/c27-22-10-9-20-15-19(7-8-21(20)16-22)17-30-12-11-23(18-30)28-26(32)29-24-5-1-2-6-25(24)33-14-4-3-13-31/h1-2,5-10,15-16,23,31H,3-4,11-14,17-18H2,(H2,28,29,32)/t23-/m1/s1 QXPNJBYJGHYSFV-HSZRJFAPSA-N 50394482 CHEMBL2159867 C-C chemokine receptor type 3 Homo sapiens 9.9 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451489 163343506 CHEMBL2159867 ZINC95575599 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961525 OCCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C24H26FN3O2/c25-21-8-7-19-13-17(5-6-20(19)14-21)15-28-11-9-22(16-28)26-24(30)27-23-4-2-1-3-18(23)10-12-29/h1-8,13-14,22,29H,9-12,15-16H2,(H2,26,27,30)/t22-/m1/s1 KNAOHDOGXQAJHN-JOCHJYFZSA-N 50394483 CHEMBL2159866 C-C chemokine receptor type 3 Homo sapiens 44 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394483&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71456816 163343507 CHEMBL2159866 ZINC95578413 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961526 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)Nc3ccccc3)ccc2c1 InChI=1S/C22H22FN3O/c23-19-9-8-17-12-16(6-7-18(17)13-19)14-26-11-10-21(15-26)25-22(27)24-20-4-2-1-3-5-20/h1-9,12-13,21H,10-11,14-15H2,(H2,24,25,27)/t21-/m1/s1 RDMCKQZPMJRRCU-OAQYLSRUSA-N 50394484 CHEMBL2159865 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394484&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71455028 163343508 CHEMBL2159865 ZINC95574370 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961527 Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)NC3CCCCC3)ccc2c1 InChI=1S/C22H28FN3O/c23-19-9-8-17-12-16(6-7-18(17)13-19)14-26-11-10-21(15-26)25-22(27)24-20-4-2-1-3-5-20/h6-9,12-13,20-21H,1-5,10-11,14-15H2,(H2,24,25,27)/t21-/m1/s1 OPBFVYPMEXZXBT-OAQYLSRUSA-N 50394485 CHEMBL2159864 C-C chemokine receptor type 3 Homo sapiens 41 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394485&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460504 163343509 CHEMBL2159864 ZINC95574271 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961528 CS(=O)(=O)N1CCC(CC1)NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C22H29FN4O3S/c1-31(29,30)27-10-7-20(8-11-27)24-22(28)25-21-6-9-26(15-21)14-16-2-3-18-13-19(23)5-4-17(18)12-16/h2-5,12-13,20-21H,6-11,14-15H2,1H3,(H2,24,25,28)/t21-/m1/s1 MRDALPNNBFAFFS-OAQYLSRUSA-N 50394486 CHEMBL2159863 C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394486&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449677 163343510 CHEMBL2159863 ZINC95578388 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961529 Oc1ccccc1S(=O)(=O)N1CCC(CC1)NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C27H31FN4O4S/c28-22-8-7-20-15-19(5-6-21(20)16-22)17-31-12-9-24(18-31)30-27(34)29-23-10-13-32(14-11-23)37(35,36)26-4-2-1-3-25(26)33/h1-8,15-16,23-24,33H,9-14,17-18H2,(H2,29,30,34)/t24-/m1/s1 KOJJXOLRRLWLNJ-XMMPIXPASA-N 50394487 CHEMBL2160111 C-C chemokine receptor type 3 Homo sapiens 2.4 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394487&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460525 163343511 CHEMBL2160111 ZINC95576228 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961530 Oc1ccccc1S(=O)(=O)N1CCC(CC1)NC(=O)N1CCCN(Cc2ccc3cc(F)ccc3c2)CC1 InChI=1S/C28H33FN4O4S/c29-24-9-8-22-18-21(6-7-23(22)19-24)20-31-12-3-13-32(17-16-31)28(35)30-25-10-14-33(15-11-25)38(36,37)27-5-2-1-4-26(27)34/h1-2,4-9,18-19,25,34H,3,10-17,20H2,(H,30,35) PVEVSTBCEFCESD-UHFFFAOYSA-N 50394488 CHEMBL2160110 C-C chemokine receptor type 3 Homo sapiens 25 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394488&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453337 163343512 CHEMBL2160110 ZINC95573127 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961531 Fc1ccc2cc(CN3CCCN(CC3)C(=O)NC3CCN(Cc4ccccc4)CC3)ccc2c1 InChI=1S/C29H35FN4O/c30-27-10-9-25-19-24(7-8-26(25)20-27)22-32-13-4-14-34(18-17-32)29(35)31-28-11-15-33(16-12-28)21-23-5-2-1-3-6-23/h1-3,5-10,19-20,28H,4,11-18,21-22H2,(H,31,35) RCRNSMOEIUFERY-UHFFFAOYSA-N 50394489 CHEMBL2160109 C-C chemokine receptor type 3 Homo sapiens 380 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394489&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460524 163343513 CHEMBL2160109 ZINC95576813 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961532 Fc1ccc2cc(CN3CCC4(CC3)OC(=O)N(Cc3ccccc3)c3ccccc43)ccc2c1 InChI=1S/C30H27FN2O2/c31-26-13-12-24-18-23(10-11-25(24)19-26)20-32-16-14-30(15-17-32)27-8-4-5-9-28(27)33(29(34)35-30)21-22-6-2-1-3-7-22/h1-13,18-19H,14-17,20-21H2 UGCGHTJRJKIYED-UHFFFAOYSA-N 50394490 CHEMBL2160108 C-C chemokine receptor type 3 Homo sapiens 2000 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394490&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462227 163343514 CHEMBL2160108 ZINC95573722 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961533 Fc1ccc2cc(CN3CCC4(CCN(CCc5ccccc5)C4=O)CC3)ccc2c1 InChI=1S/C27H29FN2O/c28-25-9-8-23-18-22(6-7-24(23)19-25)20-29-15-11-27(12-16-29)13-17-30(26(27)31)14-10-21-4-2-1-3-5-21/h1-9,18-19H,10-17,20H2 XVMZVYIOOMUWAM-UHFFFAOYSA-N 50394491 CHEMBL2160107 C-C chemokine receptor type 3 Homo sapiens 600 ChEMBL 10.1016/j.bmcl.2012.09.035 10.7270/Q2QC04MN 23046963 Nitta, A; Iura, Y; Inoue, H; Sato, I; Morihira, K; Kubota, H; Morokata, T; Takeuchi, M; Ohta, M; Tsukamoto, S; Imaoka, T; Takahashi, T Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394491&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449695 163343515 CHEMBL2160107 ZINC95577853 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969164 Cc1c(Cl)ccc(OC2CCN(CC2)C2CCN(CC2)S(=O)(=O)NC(=O)c2ccccc2)c1Cl InChI=1S/C24H29Cl2N3O4S/c1-17-21(25)7-8-22(23(17)26)33-20-11-13-28(14-12-20)19-9-15-29(16-10-19)34(31,32)27-24(30)18-5-3-2-4-6-18/h2-8,19-20H,9-16H2,1H3,(H,27,30) DJGWTFPDOGEBKS-UHFFFAOYSA-N 50397484 CHEMBL2171016 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397484&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23102749 163346508 CHEMBL2171016 ZINC59533520 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969165 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)S(=O)(=O)NC(=O)c2ccccc2)cc1Cl InChI=1S/C23H27Cl2N3O4S/c24-21-7-6-20(16-22(21)25)32-19-10-12-27(13-11-19)18-8-14-28(15-9-18)33(30,31)26-23(29)17-4-2-1-3-5-17/h1-7,16,18-19H,8-15H2,(H,26,29) SDPQHMHFTWVGGO-UHFFFAOYSA-N 50397485 CHEMBL2171015 C-C chemokine receptor type 3 Homo sapiens 79.43 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397485&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23102733 163346509 CHEMBL2171015 ZINC59533504 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969166 CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(C)c1Cl InChI=1S/C26H34Cl2N4O4S/c1-18-23(27)8-9-24(25(18)28)36-21-12-16-31(17-13-21)20-10-14-32(15-11-20)26(33)29-37(34,35)22-6-4-19(5-7-22)30(2)3/h4-9,20-21H,10-17H2,1-3H3,(H,29,33) CYAXTHULEFHIMG-UHFFFAOYSA-N 50397483 CHEMBL2171014 C-C chemokine receptor type 3 Homo sapiens 3.16 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397483&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71458868 163346507 CHEMBL2171014 ZINC95554464 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969167 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)NS(=O)(=O)Cc2ccccc2)cc1Cl InChI=1S/C24H29Cl2N3O4S/c25-22-7-6-21(16-23(22)26)33-20-10-14-28(15-11-20)19-8-12-29(13-9-19)24(30)27-34(31,32)17-18-4-2-1-3-5-18/h1-7,16,19-20H,8-15,17H2,(H,27,30) SHRVEEBUQYOBLS-UHFFFAOYSA-N 50397491 CHEMBL2171215 C-C chemokine receptor type 3 Homo sapiens 158.49 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397491&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10143016 163346515 CHEMBL2171215 ZINC34315439 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969168 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(F)c(F)c1 InChI=1S/C24H29F2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-4-7-22(25)23(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) GKKYKABOCZBQRA-UHFFFAOYSA-N 50397492 CHEMBL2171050 C-C chemokine receptor type 3 Homo sapiens 630.96 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397492&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963199 163346516 CHEMBL2171050 ZINC95555939 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969169 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)cc1 InChI=1S/C24H30ClN3O4S/c1-18-2-8-23(9-3-18)33(30,31)26-24(29)28-14-10-20(11-15-28)27-16-12-22(13-17-27)32-21-6-4-19(25)5-7-21/h2-9,20,22H,10-17H2,1H3,(H,26,29) RUMOWLXMMCFECC-UHFFFAOYSA-N 50397493 CHEMBL2171049 C-C chemokine receptor type 3 Homo sapiens 125.89 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397493&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963141 163346517 CHEMBL2171049 ZINC95555259 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969170 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)cc1C InChI=1S/C25H32ClN3O4S/c1-18-3-6-23(7-4-18)34(31,32)27-25(30)29-13-9-21(10-14-29)28-15-11-22(12-16-28)33-24-8-5-20(26)17-19(24)2/h3-8,17,21-22H,9-16H2,1-2H3,(H,27,30) IGXXJZSHANKJAD-UHFFFAOYSA-N 50397486 CHEMBL2171048 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397486&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963226 163346510 CHEMBL2171048 ZINC95552644 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969171 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(C)c1Cl InChI=1S/C25H31Cl2N3O4S/c1-17-3-5-21(6-4-17)35(32,33)28-25(31)30-13-9-19(10-14-30)29-15-11-20(12-16-29)34-23-8-7-22(26)18(2)24(23)27/h3-8,19-20H,9-16H2,1-2H3,(H,28,31) HFWLILWGBZWYRI-UHFFFAOYSA-N 50397494 CHEMBL2171047 C-C chemokine receptor type 3 Homo sapiens 0.631 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397494&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963201 163346518 CHEMBL2171047 ZINC95554148 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969172 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)cc1Cl InChI=1S/C24H29Cl2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-19(9-13-29)28-14-10-20(11-15-28)33-23-7-4-18(25)16-22(23)26/h2-7,16,19-20H,8-15H2,1H3,(H,27,30) STXMJDYUJFBELE-UHFFFAOYSA-N 50397495 CHEMBL2171046 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397495&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963153 163346519 CHEMBL2171046 ZINC95555550 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969173 FC(F)(F)c1cccc(c1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H26Cl2F3N3O4S/c25-21-5-4-19(15-22(21)26)36-18-8-12-31(13-9-18)17-6-10-32(11-7-17)23(33)30-37(34,35)20-3-1-2-16(14-20)24(27,28)29/h1-5,14-15,17-18H,6-13H2,(H,30,33) AQIZHUDMGJRAMJ-UHFFFAOYSA-N 50397496 CHEMBL2171045 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397496&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963347 163346520 CHEMBL2171045 ZINC95557649 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969174 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)NS(=O)(=O)c2cccc(c2)C#N)cc1Cl InChI=1S/C24H26Cl2N4O4S/c25-22-5-4-20(15-23(22)26)34-19-8-12-29(13-9-19)18-6-10-30(11-7-18)24(31)28-35(32,33)21-3-1-2-17(14-21)16-27/h1-5,14-15,18-19H,6-13H2,(H,28,31) NWUBEEIEKUQVJL-UHFFFAOYSA-N 50397497 CHEMBL2171044 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397497&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963336 163346521 CHEMBL2171044 ZINC42881916 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969175 Clc1cccc(c1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H26Cl3N3O4S/c24-16-2-1-3-20(14-16)34(31,32)27-23(30)29-10-6-17(7-11-29)28-12-8-18(9-13-28)33-19-4-5-21(25)22(26)15-19/h1-5,14-15,17-18H,6-13H2,(H,27,30) ZFVQRQOPWCBDOI-UHFFFAOYSA-N 50397498 CHEMBL2171043 C-C chemokine receptor type 3 Homo sapiens 6.31 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397498&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963183 163346522 CHEMBL2171043 ZINC95555808 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969176 Cc1cccc(c1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-3-2-4-21(15-17)34(31,32)27-24(30)29-11-7-18(8-12-29)28-13-9-19(10-14-28)33-20-5-6-22(25)23(26)16-20/h2-6,15-16,18-19H,7-14H2,1H3,(H,27,30) PHHPFXWDLDXLPN-UHFFFAOYSA-N 50397499 CHEMBL2171042 C-C chemokine receptor type 3 Homo sapiens 125.89 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397499&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71455217 163346523 CHEMBL2171042 ZINC95553411 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969177 CN(C)c1ccccc1S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H32Cl2N4O4S/c1-29(2)23-5-3-4-6-24(23)36(33,34)28-25(32)31-13-9-18(10-14-31)30-15-11-19(12-16-30)35-20-7-8-21(26)22(27)17-20/h3-8,17-19H,9-16H2,1-2H3,(H,28,32) GSQPHXFZLYFUQD-UHFFFAOYSA-N 50397500 CHEMBL2171041 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397500&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453505 163346524 CHEMBL2171041 ZINC95555541 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969178 COc1ccccc1S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O5S/c1-33-22-4-2-3-5-23(22)35(31,32)27-24(30)29-12-8-17(9-13-29)28-14-10-18(11-15-28)34-19-6-7-20(25)21(26)16-19/h2-7,16-18H,8-15H2,1H3,(H,27,30) UOWPMQNCLJZBEA-UHFFFAOYSA-N 50397487 CHEMBL2171040 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397487&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963332 163346511 CHEMBL2171040 ZINC95553790 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969179 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)NS(=O)(=O)c2ccccc2Cl)cc1Cl InChI=1S/C23H26Cl3N3O4S/c24-19-6-5-18(15-21(19)26)33-17-9-13-28(14-10-17)16-7-11-29(12-8-16)23(30)27-34(31,32)22-4-2-1-3-20(22)25/h1-6,15-17H,7-14H2,(H,27,30) OSUVEVWOPQLILG-UHFFFAOYSA-N 50397501 CHEMBL2171039 C-C chemokine receptor type 3 Homo sapiens 5.01 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397501&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71457010 163346525 CHEMBL2171039 ZINC42881910 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969180 Cc1ccccc1S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-4-2-3-5-23(17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-6-7-21(25)22(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) IGLADUDHPDHSRD-UHFFFAOYSA-N 50397488 CHEMBL2171038 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397488&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963334 163346512 CHEMBL2171038 ZINC95553848 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969181 CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H32Cl2N4O4S/c1-29(2)18-3-6-22(7-4-18)36(33,34)28-25(32)31-13-9-19(10-14-31)30-15-11-20(12-16-30)35-21-5-8-23(26)24(27)17-21/h3-8,17,19-20H,9-16H2,1-2H3,(H,28,32) GDRRHBZSXZXDLL-UHFFFAOYSA-N 50397502 CHEMBL2171037 C-C chemokine receptor type 3 Homo sapiens 50.12 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397502&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963258 163346526 CHEMBL2171037 ZINC95555908 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969182 COc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O5S/c1-33-18-2-5-21(6-3-18)35(31,32)27-24(30)29-12-8-17(9-13-29)28-14-10-19(11-15-28)34-20-4-7-22(25)23(26)16-20/h2-7,16-17,19H,8-15H2,1H3,(H,27,30) ZLPRNWIDJZJYMH-UHFFFAOYSA-N 50397503 CHEMBL2171036 C-C chemokine receptor type 3 Homo sapiens 39.81 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397503&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963196 163346527 CHEMBL2171036 ZINC95554595 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969183 Clc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H26Cl3N3O4S/c24-16-1-4-20(5-2-16)34(31,32)27-23(30)29-11-7-17(8-12-29)28-13-9-18(10-14-28)33-19-3-6-21(25)22(26)15-19/h1-6,15,17-18H,7-14H2,(H,27,30) LKFICSFQSQYFJF-UHFFFAOYSA-N 50397489 CHEMBL2171035 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397489&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963363 163346513 CHEMBL2171035 ZINC95554454 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969184 Fc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H26Cl2FN3O4S/c24-21-6-3-19(15-22(21)25)33-18-9-13-28(14-10-18)17-7-11-29(12-8-17)23(30)27-34(31,32)20-4-1-16(26)2-5-20/h1-6,15,17-18H,7-14H2,(H,27,30) FGWSLMPEBIIYTF-UHFFFAOYSA-N 50397504 CHEMBL2171034 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397504&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963208 163346528 CHEMBL2171034 ZINC95557347 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969185 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-4-7-22(25)23(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) QVLZVRFIGXNZMN-UHFFFAOYSA-N 50394155 CHEMBL2158814 C-C chemokine receptor type 3 Homo sapiens 6.31 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394155&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11753159 163343179 CHEMBL2158814 ZINC36412221 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969186 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)NS(=O)(=O)c2ccccc2)cc1Cl InChI=1S/C23H27Cl2N3O4S/c24-21-7-6-19(16-22(21)25)32-18-10-14-27(15-11-18)17-8-12-28(13-9-17)23(29)26-33(30,31)20-4-2-1-3-5-20/h1-7,16-18H,8-15H2,(H,26,29) MFJWXRIWIGLCGD-UHFFFAOYSA-N 50397490 CHEMBL2171033 C-C chemokine receptor type 3 Homo sapiens 15.85 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397490&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963315 163346514 CHEMBL2171033 ZINC42881926 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969187 CS(=O)(=O)c1cccc(c1)C(=O)N1CC[C@H]([C@@H](C1)C(O)=O)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H28Cl2N2O6S/c1-36(33,34)19-4-2-3-16(13-19)24(30)29-12-9-23(20(15-29)25(31)32)28-10-7-17(8-11-28)35-18-5-6-21(26)22(27)14-18/h2-6,13-14,17,20,23H,7-12,15H2,1H3,(H,31,32)/t20-,23-/m1/s1 NXHYSNCNFYHMIU-NFBKMPQASA-N 50397505 CHEMBL2171032 C-C chemokine receptor type 3 Homo sapiens 398.11 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397505&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462391 163346529 CHEMBL2171032 ZINC95555829 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969188 Cc1ccc(cc1)C(=O)N1CCC(CC1)N1CC[C@H](C[C@H]1C(O)=O)Oc1ccc(Cl)c(C)c1Cl InChI=1S/C26H30Cl2N2O4/c1-16-3-5-18(6-4-16)25(31)29-12-9-19(10-13-29)30-14-11-20(15-22(30)26(32)33)34-23-8-7-21(27)17(2)24(23)28/h3-8,19-20,22H,9-15H2,1-2H3,(H,32,33)/t20-,22+/m1/s1 UTVOOLLPUMDSJS-IRLDBZIGSA-N 50397506 CHEMBL2171031 C-C chemokine receptor type 3 Homo sapiens 2511.89 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397506&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71458870 163346530 CHEMBL2171031 ZINC95554608 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969189 Cc1ccc(cc1)C(=O)N1CCC(CC1)N1CC[C@@H](C[C@@H]1C(O)=O)Oc1ccc(Cl)c(C)c1Cl InChI=1S/C26H30Cl2N2O4/c1-16-3-5-18(6-4-16)25(31)29-12-9-19(10-13-29)30-14-11-20(15-22(30)26(32)33)34-23-8-7-21(27)17(2)24(23)28/h3-8,19-20,22H,9-15H2,1-2H3,(H,32,33)/t20-,22+/m0/s1 UTVOOLLPUMDSJS-RBBKRZOGSA-N 50397507 CHEMBL2171030 C-C chemokine receptor type 3 Homo sapiens 630.96 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397507&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71457009 163346531 CHEMBL2171030 ZINC95554233 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969190 OC(=O)CCCCn1nnc(n1)-c1ccc(cc1)C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C29H34Cl2N6O4/c30-25-9-8-24(19-26(25)31)41-23-12-17-35(18-13-23)22-10-15-36(16-11-22)29(40)21-6-4-20(5-7-21)28-32-34-37(33-28)14-2-1-3-27(38)39/h4-9,19,22-23H,1-3,10-18H2,(H,38,39) LGNOCEJCJLXMEA-UHFFFAOYSA-N 50397508 CHEMBL2171029 C-C chemokine receptor type 3 Homo sapiens 398.11 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397508&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449859 163346532 CHEMBL2171029 ZINC95557232 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969191 OC(=O)CCNc1ccccc1C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C26H31Cl2N3O4/c27-22-6-5-20(17-23(22)28)35-19-10-15-30(16-11-19)18-8-13-31(14-9-18)26(34)21-3-1-2-4-24(21)29-12-7-25(32)33/h1-6,17-19,29H,7-16H2,(H,32,33) VDNHGXHYXNDCOW-UHFFFAOYSA-N 50397509 CHEMBL2171028 C-C chemokine receptor type 3 Homo sapiens 501.19 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397509&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451671 163346533 CHEMBL2171028 ZINC95556879 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969192 OC(=O)CCCS(=O)(=O)c1cccc(c1)C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C27H32Cl2N2O6S/c28-24-7-6-22(18-25(24)29)37-21-10-14-30(15-11-21)20-8-12-31(13-9-20)27(34)19-3-1-4-23(17-19)38(35,36)16-2-5-26(32)33/h1,3-4,6-7,17-18,20-21H,2,5,8-16H2,(H,32,33) PDJBLXDNFLXACI-UHFFFAOYSA-N 50397510 CHEMBL2171027 C-C chemokine receptor type 3 Homo sapiens 79.43 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397510&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449858 163346534 CHEMBL2171027 ZINC95553361 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969193 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc(cc2)-c2nnn[nH]2)cc1Cl InChI=1S/C24H26Cl2N6O2/c25-21-6-5-20(15-22(21)26)34-19-9-13-31(14-10-19)18-7-11-32(12-8-18)24(33)17-3-1-16(2-4-17)23-27-29-30-28-23/h1-6,15,18-19H,7-14H2,(H,27,28,29,30) NQTXEWZDVUMZDO-UHFFFAOYSA-N 50397511 CHEMBL2171026 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397511&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462390 163346535 CHEMBL2171026 ZINC95554755 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969194 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc(cc2)-c2nc(=O)o[nH]2)cc1Cl InChI=1S/C25H26Cl2N4O4/c26-21-6-5-20(15-22(21)27)34-19-9-13-30(14-10-19)18-7-11-31(12-8-18)24(32)17-3-1-16(2-4-17)23-28-25(33)35-29-23/h1-6,15,18-19H,7-14H2,(H,28,29,33) QAXGZLPJWOSHHV-UHFFFAOYSA-N 50397512 CHEMBL2171025 C-C chemokine receptor type 3 Homo sapiens 316.23 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397512&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71457008 163346536 CHEMBL2171025 ZINC95553083 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969195 OC(=O)c1cccc(c1)C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H26Cl2N2O4/c25-21-5-4-20(15-22(21)26)32-19-8-12-27(13-9-19)18-6-10-28(11-7-18)23(29)16-2-1-3-17(14-16)24(30)31/h1-5,14-15,18-19H,6-13H2,(H,30,31) CSSKAGWIWQOQME-UHFFFAOYSA-N 50397513 CHEMBL2171024 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397513&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462389 163346537 CHEMBL2171024 ZINC95557754 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969196 OC(=O)c1ccccc1C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H26Cl2N2O4/c25-21-6-5-18(15-22(21)26)32-17-9-13-27(14-10-17)16-7-11-28(12-8-16)23(29)19-3-1-2-4-20(19)24(30)31/h1-6,15-17H,7-14H2,(H,30,31) RIEFZSRXHBEIFW-UHFFFAOYSA-N 50397514 CHEMBL2171023 C-C chemokine receptor type 3 Homo sapiens 251.19 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397514&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449857 163346538 CHEMBL2171023 ZINC95557571 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969197 OC(=O)COc1cccc(c1)C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H28Cl2N2O5/c26-22-5-4-21(15-23(22)27)34-19-8-12-28(13-9-19)18-6-10-29(11-7-18)25(32)17-2-1-3-20(14-17)33-16-24(30)31/h1-5,14-15,18-19H,6-13,16H2,(H,30,31) AEWQIKDEAWAPPV-UHFFFAOYSA-N 50397515 CHEMBL2171022 C-C chemokine receptor type 3 Homo sapiens 251.19 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397515&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71458869 163346539 CHEMBL2171022 ZINC95557558 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969198 Cc1c(Cl)ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc(c2)S(C)(=O)=O)c1Cl InChI=1S/C25H30Cl2N2O4S/c1-17-22(26)6-7-23(24(17)27)33-20-10-14-28(15-11-20)19-8-12-29(13-9-19)25(30)18-4-3-5-21(16-18)34(2,31)32/h3-7,16,19-20H,8-15H2,1-2H3 ATPAZLJUTRYFNR-UHFFFAOYSA-N 50397516 CHEMBL2171021 C-C chemokine receptor type 3 Homo sapiens 5.01 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397516&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69826668 163346540 CHEMBL2171021 ZINC95555836 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969199 Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2c[nH]c(=O)c3ccccc23)cc1Cl InChI=1S/C26H27Cl2N3O3/c27-23-6-5-19(15-24(23)28)34-18-9-13-30(14-10-18)17-7-11-31(12-8-17)26(33)22-16-29-25(32)21-4-2-1-3-20(21)22/h1-6,15-18H,7-14H2,(H,29,32) CCJZAFYMSHLKFH-UHFFFAOYSA-N 50397517 CHEMBL2171020 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397517&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22397445 163346541 CHEMBL2171020 ZINC95556629 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969200 CS(=O)(=O)c1cccc(c1)C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H28Cl2N2O4S/c1-33(30,31)21-4-2-3-17(15-21)24(29)28-11-7-18(8-12-28)27-13-9-19(10-14-27)32-20-5-6-22(25)23(26)16-20/h2-6,15-16,18-19H,7-14H2,1H3 UEMKNKCKJCNUSX-UHFFFAOYSA-N 50397518 CHEMBL2171019 C-C chemokine receptor type 3 Homo sapiens 50.12 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397518&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22397436 163346542 CHEMBL2171019 ZINC95557599 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969201 COc1cccc(c1)C(=O)NCCN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C21H24Cl2N2O3/c1-27-17-4-2-3-15(13-17)21(26)24-9-12-25-10-7-16(8-11-25)28-18-5-6-19(22)20(23)14-18/h2-6,13-14,16H,7-12H2,1H3,(H,24,26) WOCAUAGFAOCBHT-UHFFFAOYSA-N 50397519 CHEMBL2171018 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397519&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9910169 163346543 CHEMBL2171018 ZINC34024882 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969202 COc1ccc(cc1Cl)C(=O)NCCN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C21H24Cl3N3O2/c1-29-20-5-3-16(13-19(20)24)21(28)25-6-7-26-8-10-27(11-9-26)14-15-2-4-17(22)18(23)12-15/h2-5,12-13H,6-11,14H2,1H3,(H,25,28) CBWRUNBHLXXKIT-UHFFFAOYSA-N 50397520 CHEMBL2171017 C-C chemokine receptor type 3 Homo sapiens 5011.87 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397520&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451670 163346544 CHEMBL2171017 ZINC95552708 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969207 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-4-7-22(25)23(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) QVLZVRFIGXNZMN-UHFFFAOYSA-N 50394155 CHEMBL2158814 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394155&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11753159 163343179 CHEMBL2158814 ZINC36412221 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50969163 CN(C(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C25H31Cl2N3O4S/c1-18-3-6-22(7-4-18)35(32,33)28(2)25(31)30-13-9-19(10-14-30)29-15-11-20(12-16-29)34-21-5-8-23(26)24(27)17-21/h3-8,17,19-20H,9-16H2,1-2H3 LPHIWCBAJGQIIF-UHFFFAOYSA-N 50397482 CHEMBL2171013 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.124 10.7270/Q2QF8V00 23031591 Bahl, A; Barton, P; Bowers, K; Brough, S; Evans, R; Luckhurst, CA; Mochel, T; Perry, MW; Rigby, A; Riley, RJ; Sanganee, H; Sisson, A; Springthorpe, B AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397482&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17963227 163346506 CHEMBL2171013 ZINC95555651 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960772 Cc1cc(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@](C)(Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C28H36ClFN2O3/c1-20-17-23(29)5-8-26(20)35-25-11-13-31(14-12-25)19-22-9-15-32(16-10-22)28(2,27(33)34)18-21-3-6-24(30)7-4-21/h3-8,17,22,25H,9-16,18-19H2,1-2H3,(H,33,34)/t28-/m0/s1 AQVKRBFXFFKXJV-NDEPHWFRSA-N 50394114 CHEMBL2158791 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394114&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 16040671 163343138 CHEMBL2158791 ZINC34884564 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960827 Cc1cc(F)ccc1OC1CCN(CC2CCN(CC2)[C@@](C)(Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C28H36F2N2O3/c1-20-17-24(30)7-8-26(20)35-25-11-13-31(14-12-25)19-22-9-15-32(16-10-22)28(2,27(33)34)18-21-3-5-23(29)6-4-21/h3-8,17,22,25H,9-16,18-19H2,1-2H3,(H,33,34)/t28-/m0/s1 LLEJNWFSXZIFMW-NDEPHWFRSA-N 50394112 CHEMBL2158793 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394112&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71456722 163343136 CHEMBL2158793 ZINC95574910 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960828 Cc1cc(OC2CCN(CC3CCN(CC3)[C@@](C)(Cc3ccc(F)cc3)C(O)=O)CC2)ccc1Cl InChI=1S/C28H36ClFN2O3/c1-20-17-25(7-8-26(20)29)35-24-11-13-31(14-12-24)19-22-9-15-32(16-10-22)28(2,27(33)34)18-21-3-5-23(30)6-4-21/h3-8,17,22,24H,9-16,18-19H2,1-2H3,(H,33,34)/t28-/m0/s1 LEHDCEDFGAFVGX-NDEPHWFRSA-N 50394113 CHEMBL2158792 C-C chemokine receptor type 3 Homo sapiens 1.26 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394113&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462100 163343137 CHEMBL2158792 ZINC95574378 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960829 Cc1cc(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@](C)(Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C28H36ClFN2O3/c1-20-17-23(29)5-8-26(20)35-25-11-13-31(14-12-25)19-22-9-15-32(16-10-22)28(2,27(33)34)18-21-3-6-24(30)7-4-21/h3-8,17,22,25H,9-16,18-19H2,1-2H3,(H,33,34)/t28-/m0/s1 AQVKRBFXFFKXJV-NDEPHWFRSA-N 50394114 CHEMBL2158791 C-C chemokine receptor type 3 Homo sapiens 0.631 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394114&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 16040671 163343138 CHEMBL2158791 ZINC34884564 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960830 Cc1c(Cl)c(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@](C)(Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C28H35Cl2FN2O3/c1-19-25(8-7-24(29)26(19)30)36-23-11-13-32(14-12-23)18-21-9-15-33(16-10-21)28(2,27(34)35)17-20-3-5-22(31)6-4-20/h3-8,21,23H,9-18H2,1-2H3,(H,34,35)/t28-/m0/s1 AYPGYVOWMUSFPT-NDEPHWFRSA-N 50394157 CHEMBL2158790 C-C chemokine receptor type 3 Homo sapiens 0.2 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394157&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615627 163343181 CHEMBL2158790 ZINC43151886 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960831 Cc1c(Cl)c(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@](C)(Cc2ccccc2)C(O)=O)CC1 InChI=1S/C28H36Cl2N2O3/c1-20-25(9-8-24(29)26(20)30)35-23-12-14-31(15-13-23)19-22-10-16-32(17-11-22)28(2,27(33)34)18-21-6-4-3-5-7-21/h3-9,22-23H,10-19H2,1-2H3,(H,33,34)/t28-/m0/s1 TYDWSEQLTIBAPO-NDEPHWFRSA-N 50394158 CHEMBL2158789 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394158&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615691 163343182 CHEMBL2158789 ZINC95576775 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960832 Cc1c(Cl)c(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccccc2)C(O)=O)CC1 InChI=1S/C27H34Cl2N2O3/c1-19-25(8-7-23(28)26(19)29)34-22-11-13-30(14-12-22)18-21-9-15-31(16-10-21)24(27(32)33)17-20-5-3-2-4-6-20/h2-8,21-22,24H,9-18H2,1H3,(H,32,33)/t24-/m0/s1 MYZGZNJBQOQRTJ-DEOSSOPVSA-N 50394159 CHEMBL2158788 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394159&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615617 163343183 CHEMBL2158788 ZINC95576237 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960833 C[C@@](Cc1ccc(F)cc1)(N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)C(O)=O InChI=1S/C27H33Cl2FN2O3/c1-27(26(33)34,17-19-2-4-21(30)5-3-19)32-14-8-20(9-15-32)18-31-12-10-22(11-13-31)35-23-6-7-24(28)25(29)16-23/h2-7,16,20,22H,8-15,17-18H2,1H3,(H,33,34)/t27-/m0/s1 YDHQRFQQOKRWAD-MHZLTWQESA-N 50394160 CHEMBL2158787 C-C chemokine receptor type 3 Homo sapiens 0.794 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394160&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615702 163343184 CHEMBL2158787 ZINC95573755 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960834 C[C@@](Cc1ccccc1)(N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)C(O)=O InChI=1S/C27H34Cl2N2O3/c1-27(26(32)33,18-20-5-3-2-4-6-20)31-15-9-21(10-16-31)19-30-13-11-22(12-14-30)34-23-7-8-24(28)25(29)17-23/h2-8,17,21-22H,9-16,18-19H2,1H3,(H,32,33)/t27-/m0/s1 ZNOFXQRZLXBDTB-MHZLTWQESA-N 50394161 CHEMBL2158786 C-C chemokine receptor type 3 Homo sapiens 3.16 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394161&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451392 163343185 CHEMBL2158786 ZINC95572061 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960835 Cc1c(Cl)c(ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccc(F)cc2)C(O)=O)CC1)C#N InChI=1S/C28H33ClFN3O3/c1-19-26(7-4-22(17-31)27(19)29)36-24-10-12-32(13-11-24)18-21-8-14-33(15-9-21)25(28(34)35)16-20-2-5-23(30)6-3-20/h2-7,21,24-25H,8-16,18H2,1H3,(H,34,35)/t25-/m0/s1 GEMBQNHUTJFAFL-VWLOTQADSA-N 50394115 CHEMBL2158785 C-C chemokine receptor type 3 Homo sapiens 1.26 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394115&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615606 163343139 CHEMBL2158785 ZINC95572654 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960836 Cc1c(Cl)c(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C27H33Cl2FN2O3/c1-18-25(7-6-23(28)26(18)29)35-22-10-12-31(13-11-22)17-20-8-14-32(15-9-20)24(27(33)34)16-19-2-4-21(30)5-3-19/h2-7,20,22,24H,8-17H2,1H3,(H,33,34)/t24-/m0/s1 WKNWCTUFTMDACE-DEOSSOPVSA-N 50394116 CHEMBL2158784 C-C chemokine receptor type 3 Homo sapiens 0.501 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394116&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 12001832 163343140 CHEMBL2158784 ZINC34885147 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960837 Cc1c(Cl)ccc(OC2CCN(CC3CCN(CC3)[C@@H](Cc3ccc(F)cc3)C(O)=O)CC2)c1Cl InChI=1S/C27H33Cl2FN2O3/c1-18-23(28)6-7-25(26(18)29)35-22-10-12-31(13-11-22)17-20-8-14-32(15-9-20)24(27(33)34)16-19-2-4-21(30)5-3-19/h2-7,20,22,24H,8-17H2,1H3,(H,33,34)/t24-/m0/s1 SEIOTCVWLCUESB-DEOSSOPVSA-N 50394117 CHEMBL2158783 C-C chemokine receptor type 3 Homo sapiens 0.501 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394117&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615619 163343141 CHEMBL2158783 ZINC95572037 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960838 Cc1cc(OC2CCN(CC3CCN(CC3)[C@@H](Cc3ccc(F)cc3)C(O)=O)CC2)ccc1Cl InChI=1S/C27H34ClFN2O3/c1-19-16-24(6-7-25(19)28)34-23-10-12-30(13-11-23)18-21-8-14-31(15-9-21)26(27(32)33)17-20-2-4-22(29)5-3-20/h2-7,16,21,23,26H,8-15,17-18H2,1H3,(H,32,33)/t26-/m0/s1 HLXZPGHNFUSVMT-SANMLTNESA-N 50394118 CHEMBL2158782 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394118&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71453204 163343142 CHEMBL2158782 ZINC95577373 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960839 Cc1cc(F)ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C27H34F2N2O3/c1-19-16-23(29)6-7-26(19)34-24-10-12-30(13-11-24)18-21-8-14-31(15-9-21)25(27(32)33)17-20-2-4-22(28)5-3-20/h2-7,16,21,24-25H,8-15,17-18H2,1H3,(H,32,33)/t25-/m0/s1 CWXOTCCLEKNUJY-VWLOTQADSA-N 50394119 CHEMBL2158781 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394119&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451391 163343143 CHEMBL2158781 ZINC95578458 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960840 Cc1cc(Cl)ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccc(F)cc2)C(O)=O)CC1 InChI=1S/C27H34ClFN2O3/c1-19-16-22(28)4-7-26(19)34-24-10-12-30(13-11-24)18-21-8-14-31(15-9-21)25(27(32)33)17-20-2-5-23(29)6-3-20/h2-7,16,21,24-25H,8-15,17-18H2,1H3,(H,32,33)/t25-/m0/s1 MOHMWXTYADLKCG-VWLOTQADSA-N 50394120 CHEMBL2158780 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394120&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615678 163343144 CHEMBL2158780 ZINC95580616 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960841 OC(=O)[C@H](Cc1ccc(F)cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)cc2Cl)CC1 InChI=1S/C26H31Cl2FN2O3/c27-20-3-6-25(23(28)16-20)34-22-9-11-30(12-10-22)17-19-7-13-31(14-8-19)24(26(32)33)15-18-1-4-21(29)5-2-18/h1-6,16,19,22,24H,7-15,17H2,(H,32,33)/t24-/m0/s1 NHOMRPYETSURDH-DEOSSOPVSA-N 50394121 CHEMBL2158779 C-C chemokine receptor type 3 Homo sapiens 5.01 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394121&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 66615705 163343145 CHEMBL2158779 ZINC95573788 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960842 OC(=O)[C@H](Cc1ccc(F)cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)cc2)CC1 InChI=1S/C26H32ClFN2O3/c27-21-3-7-23(8-4-21)33-24-11-13-29(14-12-24)18-20-9-15-30(16-10-20)25(26(31)32)17-19-1-5-22(28)6-2-19/h1-8,20,24-25H,9-18H2,(H,31,32)/t25-/m0/s1 BATQCPTUBUKUDO-VWLOTQADSA-N 50394122 CHEMBL2158778 C-C chemokine receptor type 3 Homo sapiens 50.12 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394122&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71451390 163343146 CHEMBL2158778 ZINC95576194 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960843 OC(=O)[C@H](Cc1cccc(c1)C(F)(F)F)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H31Cl2F3N2O3/c28-23-5-4-22(16-24(23)29)37-21-8-10-33(11-9-21)17-18-6-12-34(13-7-18)25(26(35)36)15-19-2-1-3-20(14-19)27(30,31)32/h1-5,14,16,18,21,25H,6-13,15,17H2,(H,35,36)/t25-/m0/s1 NMLHPAJBQUFHAV-VWLOTQADSA-N 50394123 CHEMBL2158777 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394123&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11444350 163343147 CHEMBL2158777 ZINC95576746 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960844 COc1ccc(C[C@H](N2CCC(CN3CCC(CC3)Oc3ccc(Cl)c(Cl)c3)CC2)C(O)=O)cc1 InChI=1S/C27H34Cl2N2O4/c1-34-21-4-2-19(3-5-21)16-26(27(32)33)31-14-8-20(9-15-31)18-30-12-10-22(11-13-30)35-23-6-7-24(28)25(29)17-23/h2-7,17,20,22,26H,8-16,18H2,1H3,(H,32,33)/t26-/m0/s1 RMSWKUOSOVPFPF-SANMLTNESA-N 50394124 CHEMBL2158776 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394124&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460416 163343148 CHEMBL2158776 ZINC95607155 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960845 COc1ccccc1C[C@H](N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)C(O)=O InChI=1S/C27H34Cl2N2O4/c1-34-26-5-3-2-4-20(26)16-25(27(32)33)31-14-8-19(9-15-31)18-30-12-10-21(11-13-30)35-22-6-7-23(28)24(29)17-22/h2-7,17,19,21,25H,8-16,18H2,1H3,(H,32,33)/t25-/m0/s1 VOPUEJLKUSXAOZ-VWLOTQADSA-N 50394125 CHEMBL2158775 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394125&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072104 163343149 CHEMBL2158775 ZINC95573145 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960846 Cc1ccc(C[C@H](N2CCC(CN3CCC(CC3)Oc3ccc(Cl)c(Cl)c3)CC2)C(O)=O)cc1 InChI=1S/C27H34Cl2N2O3/c1-19-2-4-20(5-3-19)16-26(27(32)33)31-14-8-21(9-15-31)18-30-12-10-22(11-13-30)34-23-6-7-24(28)25(29)17-23/h2-7,17,21-22,26H,8-16,18H2,1H3,(H,32,33)/t26-/m0/s1 QLGIWKYNMSCERQ-SANMLTNESA-N 50394126 CHEMBL2158774 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394126&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072113 163343150 CHEMBL2158774 ZINC95576749 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960847 Cc1cccc(C[C@H](N2CCC(CN3CCC(CC3)Oc3ccc(Cl)c(Cl)c3)CC2)C(O)=O)c1 InChI=1S/C27H34Cl2N2O3/c1-19-3-2-4-21(15-19)16-26(27(32)33)31-13-7-20(8-14-31)18-30-11-9-22(10-12-30)34-23-5-6-24(28)25(29)17-23/h2-6,15,17,20,22,26H,7-14,16,18H2,1H3,(H,32,33)/t26-/m0/s1 CGPUMTTUBWGRHT-SANMLTNESA-N 50394127 CHEMBL2158773 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394127&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072081 163343151 CHEMBL2158773 ZINC95574387 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960848 Cc1ccccc1C[C@H](N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)C(O)=O InChI=1S/C27H34Cl2N2O3/c1-19-4-2-3-5-21(19)16-26(27(32)33)31-14-8-20(9-15-31)18-30-12-10-22(11-13-30)34-23-6-7-24(28)25(29)17-23/h2-7,17,20,22,26H,8-16,18H2,1H3,(H,32,33)/t26-/m0/s1 GKKOWDZJMOVEBY-SANMLTNESA-N 50394128 CHEMBL2158772 C-C chemokine receptor type 3 Homo sapiens 5.01 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394128&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68938028 163343152 CHEMBL2158772 ZINC95577353 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960849 OC(=O)[C@H](Cc1ccc(cc1)C#N)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H31Cl2N3O3/c28-24-6-5-23(16-25(24)29)35-22-9-11-31(12-10-22)18-21-7-13-32(14-8-21)26(27(33)34)15-19-1-3-20(17-30)4-2-19/h1-6,16,21-22,26H,7-15,18H2,(H,33,34)/t26-/m0/s1 VNYAKKUPVDUAEG-SANMLTNESA-N 50394129 CHEMBL2158771 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394129&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072052 163343153 CHEMBL2158771 ZINC95579530 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960850 OC(=O)[C@H](Cc1cccc(c1)C#N)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H31Cl2N3O3/c28-24-5-4-23(16-25(24)29)35-22-8-10-31(11-9-22)18-19-6-12-32(13-7-19)26(27(33)34)15-20-2-1-3-21(14-20)17-30/h1-5,14,16,19,22,26H,6-13,15,18H2,(H,33,34)/t26-/m0/s1 QIUVHPATBGGVRR-SANMLTNESA-N 50394130 CHEMBL2158770 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394130&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072115 163343154 CHEMBL2158770 ZINC95577341 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960851 OC(=O)[C@H](Cc1ccccc1C#N)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H31Cl2N3O3/c28-24-6-5-23(16-25(24)29)35-22-9-11-31(12-10-22)18-19-7-13-32(14-8-19)26(27(33)34)15-20-3-1-2-4-21(20)17-30/h1-6,16,19,22,26H,7-15,18H2,(H,33,34)/t26-/m0/s1 WCXUWQZNCRRRDD-SANMLTNESA-N 50394131 CHEMBL2158769 C-C chemokine receptor type 3 Homo sapiens 5.01 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394131&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9914506 163343155 CHEMBL2158769 ZINC34026667 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960852 OC(=O)[C@H](Cc1ccc(F)cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H31Cl2FN2O3/c27-23-6-5-22(16-24(23)28)34-21-9-11-30(12-10-21)17-19-7-13-31(14-8-19)25(26(32)33)15-18-1-3-20(29)4-2-18/h1-6,16,19,21,25H,7-15,17H2,(H,32,33)/t25-/m0/s1 UJDYUOWUTALBPP-VWLOTQADSA-N 50394162 CHEMBL2158841 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394162&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072118 163343186 CHEMBL2158841 ZINC95574922 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960853 OC(=O)[C@H](Cc1cccc(F)c1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H31Cl2FN2O3/c27-23-5-4-22(16-24(23)28)34-21-8-10-30(11-9-21)17-18-6-12-31(13-7-18)25(26(32)33)15-19-2-1-3-20(29)14-19/h1-5,14,16,18,21,25H,6-13,15,17H2,(H,32,33)/t25-/m0/s1 MANRLQSCJCTMOZ-VWLOTQADSA-N 50394132 CHEMBL2158840 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394132&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072057 163343156 CHEMBL2158840 ZINC95573718 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960854 OC(=O)[C@H](Cc1ccccc1F)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H31Cl2FN2O3/c27-22-6-5-21(16-23(22)28)34-20-9-11-30(12-10-20)17-18-7-13-31(14-8-18)25(26(32)33)15-19-3-1-2-4-24(19)29/h1-6,16,18,20,25H,7-15,17H2,(H,32,33)/t25-/m0/s1 YFTFPJHCROIDGR-VWLOTQADSA-N 50394133 CHEMBL2158839 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394133&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072050 163343157 CHEMBL2158839 ZINC95573194 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960855 OC(=O)[C@H](Cc1ccc(Cl)cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H31Cl3N2O3/c27-20-3-1-18(2-4-20)15-25(26(32)33)31-13-7-19(8-14-31)17-30-11-9-21(10-12-30)34-22-5-6-23(28)24(29)16-22/h1-6,16,19,21,25H,7-15,17H2,(H,32,33)/t25-/m0/s1 KCLONPRRKHVPLU-VWLOTQADSA-N 50394134 CHEMBL2158838 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394134&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71460419 163343158 CHEMBL2158838 ZINC95571999 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960856 OC(=O)[C@H](Cc1ccccc1Cl)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H31Cl3N2O3/c27-22-4-2-1-3-19(22)15-25(26(32)33)31-13-7-18(8-14-31)17-30-11-9-20(10-12-30)34-21-5-6-23(28)24(29)16-21/h1-6,16,18,20,25H,7-15,17H2,(H,32,33)/t25-/m0/s1 IUIGATKKQCOBAF-VWLOTQADSA-N 50394135 CHEMBL2158837 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394135&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072044 163343159 CHEMBL2158837 ZINC95576196 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960857 OC(=O)[C@@H](Cc1ccccc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H32Cl2N2O3/c27-23-7-6-22(17-24(23)28)33-21-10-12-29(13-11-21)18-20-8-14-30(15-9-20)25(26(31)32)16-19-4-2-1-3-5-19/h1-7,17,20-21,25H,8-16,18H2,(H,31,32)/t25-/m1/s1 YDRCHQQFHSPVMO-RUZDIDTESA-N 50394136 CHEMBL2158836 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394136&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072034 163343160 CHEMBL2158836 ZINC95573766 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960858 OC(=O)[C@H](Cc1ccccc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H32Cl2N2O3/c27-23-7-6-22(17-24(23)28)33-21-10-12-29(13-11-21)18-20-8-14-30(15-9-20)25(26(31)32)16-19-4-2-1-3-5-19/h1-7,17,20-21,25H,8-16,18H2,(H,31,32)/t25-/m0/s1 YDRCHQQFHSPVMO-VWLOTQADSA-N 50394137 CHEMBL2158835 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394137&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71072040 163343161 CHEMBL2158835 ZINC95573793 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960859 OC(=O)c1cccnc1N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C23H27Cl2N3O3/c24-20-4-3-18(14-21(20)25)31-17-7-10-27(11-8-17)15-16-5-12-28(13-6-16)22-19(23(29)30)2-1-9-26-22/h1-4,9,14,16-17H,5-8,10-13,15H2,(H,29,30) ROQGCKBWSKAVEH-UHFFFAOYSA-N 50394138 CHEMBL2158834 C-C chemokine receptor type 3 Homo sapiens 630.96 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394138&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69260079 163343162 CHEMBL2158834 ZINC95576763 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960860 OC(=O)c1ccc(CN2CCC(CN3CCC(CC3)Oc3ccc(Cl)c(Cl)c3)CC2)cc1 InChI=1S/C25H30Cl2N2O3/c26-23-6-5-22(15-24(23)27)32-21-9-13-29(14-10-21)17-19-7-11-28(12-8-19)16-18-1-3-20(4-2-18)25(30)31/h1-6,15,19,21H,7-14,16-17H2,(H,30,31) REJVZJBLJWRHQL-UHFFFAOYSA-N 50394139 CHEMBL2158833 C-C chemokine receptor type 3 Homo sapiens 630.96 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394139&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69347707 163343163 CHEMBL2158833 ZINC95577309 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960861 OC(=O)c1cccc(CN2CCC(CN3CCC(CC3)Oc3ccc(Cl)c(Cl)c3)CC2)c1 InChI=1S/C25H30Cl2N2O3/c26-23-5-4-22(15-24(23)27)32-21-8-12-29(13-9-21)16-18-6-10-28(11-7-18)17-19-2-1-3-20(14-19)25(30)31/h1-5,14-15,18,21H,6-13,16-17H2,(H,30,31) JVDFBAQLTSMMBQ-UHFFFAOYSA-N 50394140 CHEMBL2158832 C-C chemokine receptor type 3 Homo sapiens 251.19 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394140&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69347980 163343164 CHEMBL2158832 ZINC95577320 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960862 OC(=O)c1ccccc1CN1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O3/c26-23-6-5-21(15-24(23)27)32-20-9-13-28(14-10-20)16-18-7-11-29(12-8-18)17-19-3-1-2-4-22(19)25(30)31/h1-6,15,18,20H,7-14,16-17H2,(H,30,31) DMQWGZFKPDYZCH-UHFFFAOYSA-N 50394141 CHEMBL2158831 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394141&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69347719 163343165 CHEMBL2158831 ZINC95574348 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960863 OC(=O)COc1ccc(cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O4/c26-23-6-5-22(15-24(23)27)33-21-9-11-28(12-10-21)16-18-7-13-29(14-8-18)19-1-3-20(4-2-19)32-17-25(30)31/h1-6,15,18,21H,7-14,16-17H2,(H,30,31) DKVGJRLHFIQFEM-UHFFFAOYSA-N 50394142 CHEMBL2158830 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394142&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462103 163343166 CHEMBL2158830 ZINC95572560 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960864 OC(=O)COc1cccc(c1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O4/c26-23-5-4-22(15-24(23)27)33-20-8-10-28(11-9-20)16-18-6-12-29(13-7-18)19-2-1-3-21(14-19)32-17-25(30)31/h1-5,14-15,18,20H,6-13,16-17H2,(H,30,31) VLUYCVQWTQUWPI-UHFFFAOYSA-N 50394143 CHEMBL2158829 C-C chemokine receptor type 3 Homo sapiens 39.81 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394143&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449585 163343167 CHEMBL2158829 ZINC11686604 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960865 OC(=O)COc1ccccc1N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O4/c26-21-6-5-20(15-22(21)27)33-19-9-11-28(12-10-19)16-18-7-13-29(14-8-18)23-3-1-2-4-24(23)32-17-25(30)31/h1-6,15,18-19H,7-14,16-17H2,(H,30,31) MNSGCVNHLLGCDG-UHFFFAOYSA-N 50394144 CHEMBL2158828 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394144&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69272932 163343168 CHEMBL2158828 ZINC95579047 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960866 OC(=O)Cc1ccc(cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O3/c26-23-6-5-22(16-24(23)27)32-21-9-11-28(12-10-21)17-19-7-13-29(14-8-19)20-3-1-18(2-4-20)15-25(30)31/h1-6,16,19,21H,7-15,17H2,(H,30,31) FOQNONLDPFMOKP-UHFFFAOYSA-N 50394145 CHEMBL2158827 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394145&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71456725 163343169 CHEMBL2158827 C03768 ZINC95580075 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960867 OC(=O)Cc1cccc(c1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O3/c26-23-5-4-22(16-24(23)27)32-21-8-10-28(11-9-21)17-18-6-12-29(13-7-18)20-3-1-2-19(14-20)15-25(30)31/h1-5,14,16,18,21H,6-13,15,17H2,(H,30,31) VTIFNIOOCLEWLJ-UHFFFAOYSA-N 50394146 CHEMBL2158826 C-C chemokine receptor type 3 Homo sapiens 39.81 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394146&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69274365 163343170 CHEMBL2158826 ZINC11686606 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960868 OC(=O)Cc1ccccc1N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H30Cl2N2O3/c26-22-6-5-21(16-23(22)27)32-20-9-11-28(12-10-20)17-18-7-13-29(14-8-18)24-4-2-1-3-19(24)15-25(30)31/h1-6,16,18,20H,7-15,17H2,(H,30,31) CCXXDPNVVABEGJ-UHFFFAOYSA-N 50394147 CHEMBL2158825 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394147&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449584 163343171 CHEMBL2158825 ZINC95573195 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960869 OC(=O)c1ccc(cc1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H28Cl2N2O3/c25-22-6-5-21(15-23(22)26)31-20-9-11-27(12-10-20)16-17-7-13-28(14-8-17)19-3-1-18(2-4-19)24(29)30/h1-6,15,17,20H,7-14,16H2,(H,29,30) CUIDNQSCWXAPRS-UHFFFAOYSA-N 50394148 CHEMBL2158824 C-C chemokine receptor type 3 Homo sapiens 158.49 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394148&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69260851 163343172 CHEMBL2158824 ZINC95577890 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960870 OC(=O)c1cccc(c1)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H28Cl2N2O3/c25-22-5-4-21(15-23(22)26)31-20-8-10-27(11-9-20)16-17-6-12-28(13-7-17)19-3-1-2-18(14-19)24(29)30/h1-5,14-15,17,20H,6-13,16H2,(H,29,30) SUHCNXHLKUQVER-UHFFFAOYSA-N 50394149 CHEMBL2158823 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394149&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69260946 163343173 CHEMBL2158823 ZINC95573716 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960871 OC(=O)c1ccccc1N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H28Cl2N2O3/c25-21-6-5-19(15-22(21)26)31-18-9-11-27(12-10-18)16-17-7-13-28(14-8-17)23-4-2-1-3-20(23)24(29)30/h1-6,15,17-18H,7-14,16H2,(H,29,30) UMSPPMMERAOIRT-UHFFFAOYSA-N 50394150 CHEMBL2158822 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394150&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69262172 163343174 CHEMBL2158822 ZINC95573155 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960872 OC(=O)[C@H](N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 InChI=1S/C25H30Cl2N2O3/c26-22-7-6-21(16-23(22)27)32-20-10-12-28(13-11-20)17-18-8-14-29(15-9-18)24(25(30)31)19-4-2-1-3-5-19/h1-7,16,18,20,24H,8-15,17H2,(H,30,31)/t24-/m1/s1 JHJPBZPNRYMQKP-XMMPIXPASA-N 50394151 CHEMBL2158821 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394151&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69347575 163343175 CHEMBL2158821 ZINC13975966 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960873 OC(=O)[C@@H](N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 InChI=1S/C25H30Cl2N2O3/c26-22-7-6-21(16-23(22)27)32-20-10-12-28(13-11-20)17-18-8-14-29(15-9-18)24(25(30)31)19-4-2-1-3-5-19/h1-7,16,18,20,24H,8-15,17H2,(H,30,31)/t24-/m0/s1 JHJPBZPNRYMQKP-DEOSSOPVSA-N 50394152 CHEMBL2158820 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394152&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69348078 163343176 CHEMBL2158820 ZINC03948316 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960874 OC(=O)[C@H](N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1)c1ccccc1 InChI=1S/C25H30Cl2N2O3/c26-22-7-6-21(16-23(22)27)32-20-10-12-28(13-11-20)17-18-8-14-29(15-9-18)24(25(30)31)19-4-2-1-3-5-19/h1-7,16,18,20,24H,8-15,17H2,(H,30,31)/t24-/m1/s1 JHJPBZPNRYMQKP-XMMPIXPASA-N 50394151 CHEMBL2158821 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394151&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 69347575 163343175 CHEMBL2158821 ZINC13975966 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960875 OC(=O)C(N1CCO[C@H](CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)C1)c1ccccc1 InChI=1S/C24H28Cl2N2O4/c25-21-7-6-19(14-22(21)26)32-18-8-10-27(11-9-18)15-20-16-28(12-13-31-20)23(24(29)30)17-4-2-1-3-5-17/h1-7,14,18,20,23H,8-13,15-16H2,(H,29,30)/t20-,23?/m1/s1 DCPIUFZZSDRFTC-PPUHSXQSSA-N 50394153 CHEMBL2158818 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394153&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68849581 163343177 CHEMBL2158818 ZINC95574879 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960876 OC(=O)C(N1CCO[C@@H](CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)C1)c1ccccc1 InChI=1S/C24H28Cl2N2O4/c25-21-7-6-19(14-22(21)26)32-18-8-10-27(11-9-18)15-20-16-28(12-13-31-20)23(24(29)30)17-4-2-1-3-5-17/h1-7,14,18,20,23H,8-13,15-16H2,(H,29,30)/t20-,23?/m0/s1 DCPIUFZZSDRFTC-AJZOCDQUSA-N 50394163 CHEMBL2158817 C-C chemokine receptor type 3 Homo sapiens 125.89 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394163&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71462102 163343187 CHEMBL2158817 ZINC95576222 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960877 OC(=O)C(N1CCCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)C1)c1ccccc1 InChI=1S/C25H30Cl2N2O3/c26-22-9-8-21(15-23(22)27)32-20-10-13-28(14-11-20)16-18-5-4-12-29(17-18)24(25(30)31)19-6-2-1-3-7-19/h1-3,6-9,15,18,20,24H,4-5,10-14,16-17H2,(H,30,31) FLDDBSYUKQDTDX-UHFFFAOYSA-N 50394154 CHEMBL2158816 C-C chemokine receptor type 3 Homo sapiens 79.43 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394154&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68846936 163343178 CHEMBL2158816 ZINC72280199 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960878 OC(=O)C(N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1)c1ccccc1 InChI=1S/C24H28Cl2N2O3/c25-21-7-6-20(16-22(21)26)31-19-10-14-27(15-11-19)18-8-12-28(13-9-18)23(24(29)30)17-4-2-1-3-5-17/h1-7,16,18-19,23H,8-15H2,(H,29,30) DWNROPYUHGRJJG-UHFFFAOYSA-N 50394156 CHEMBL2158815 C-C chemokine receptor type 3 Homo sapiens 39.81 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394156&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10151756 163343180 CHEMBL2158815 ZINC34324860 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50960879 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-4-7-22(25)23(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) QVLZVRFIGXNZMN-UHFFFAOYSA-N 50394155 CHEMBL2158814 C-C chemokine receptor type 3 Homo sapiens 6.31 ChEMBL 10.1016/j.bmcl.2012.08.103 10.7270/Q2Z320SD 23021991 Bahl, A; Barton, P; Bowers, K; Caffrey, MV; Denton, R; Gilmour, P; Hawley, S; Linannen, T; Luckhurst, CA; Mochel, T; Perry, MW; Riley, RJ; Roe, E; Springthorpe, B; Stein, L; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394155&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11753159 163343179 CHEMBL2158814 ZINC36412221 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50973525 CC(C)[C@@H](NC(=O)c1ccccc1)C(=O)N1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C23H27ClN2O2/c1-16(2)21(25-22(27)19-6-4-3-5-7-19)23(28)26-14-12-18(13-15-26)17-8-10-20(24)11-9-17/h3-11,16,18,21H,12-15H2,1-2H3,(H,25,27)/t21-/m1/s1 TYQNFWIJWOXJPV-OAQYLSRUSA-N 50399208 CHEMBL2180528 C-C chemokine receptor type 3 Homo sapiens >30000 ChEMBL 10.1021/jm300896d 10.7270/Q2ST7R0S 23075267 Cavallaro, CL; Briceno, S; Chen, J; Cvijic, ME; Davies, P; Hynes, J; Liu, RQ; Mandlekar, S; Rose, AV; Tebben, AJ; Van Kirk, K; Watson, A; Wu, H; Yang, G; Carter, PH Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399208&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 24758044 163348232 CHEMBL2180528 ZINC95577961 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961295 Fc1ccc(SCCCN2CCC(CC2)n2c(CC(F)(F)F)nc3cc(F)ccc23)cc1 InChI=1S/C23H24F5N3S/c24-16-2-5-19(6-3-16)32-13-1-10-30-11-8-18(9-12-30)31-21-7-4-17(25)14-20(21)29-22(31)15-23(26,27)28/h2-7,14,18H,1,8-13,15H2 CBWIHQUMXLBCET-UHFFFAOYSA-N 50394355 CHEMBL2159766 C-C chemokine receptor type 3 Homo sapiens 9 ChEMBL 10.1016/j.bmc.2012.09.013 10.7270/Q20V8DWW 23031649 Bansal, Y; Silakari, O Punjabi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394355&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11397231 163343379 CHEMBL2159766 ZINC13980365 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50961296 Fc1ccc2n(C3CCNCC3)c(CC(F)(F)F)nc2c1 InChI=1S/C14H15F4N3/c15-9-1-2-12-11(7-9)20-13(8-14(16,17)18)21(12)10-3-5-19-6-4-10/h1-2,7,10,19H,3-6,8H2 FBEIEVLGOHZRAO-UHFFFAOYSA-N 50394356 CHEMBL2159765 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmc.2012.09.013 10.7270/Q20V8DWW 23031649 Bansal, Y; Silakari, O Punjabi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394356&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 17989653 163343380 CHEMBL2159765 ZINC95577308 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971338 Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H29Cl2N3O4S/c1-17-2-5-21(6-3-17)34(31,32)27-24(30)29-12-8-18(9-13-29)28-14-10-19(11-15-28)33-20-4-7-22(25)23(26)16-20/h2-7,16,18-19H,8-15H2,1H3,(H,27,30) QVLZVRFIGXNZMN-UHFFFAOYSA-N 50394155 CHEMBL2158814 C-C chemokine receptor type 3 Homo sapiens 8.1 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50394155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50394155&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11753159 163343179 CHEMBL2158814 ZINC36412221 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971339 NC(=O)c1ccc(CNC(=O)NC[C@@H]2CN(Cc3ccc(Cl)c(Cl)c3)CCO2)cc1 InChI=1S/C21H24Cl2N4O3/c22-18-6-3-15(9-19(18)23)12-27-7-8-30-17(13-27)11-26-21(29)25-10-14-1-4-16(5-2-14)20(24)28/h1-6,9,17H,7-8,10-13H2,(H2,24,28)(H2,25,26,29)/t17-/m1/s1 GPLUUMAKBFSDIE-QGZVFWFLSA-N 50398342 CHEMBL2178574 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398342&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9825034 163347366 CHEMBL2178574 ZINC00594330 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971342 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.034 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971343 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971368 Cc1ccc(nn1)C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 InChI=1S/C28H30FN5O2/c1-19-2-7-26(32-31-19)28(36)34-12-8-20(9-13-34)15-27(35)30-25-10-11-33(18-25)17-21-3-4-23-16-24(29)6-5-22(23)14-21/h2-7,14-16,25H,8-13,17-18H2,1H3,(H,30,35)/t25-/m1/s1 OIXSYJAHIPQFMO-RUZDIDTESA-N 50398349 CHEMBL2178580 C-C chemokine receptor type 3 Homo sapiens 1.8 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398349&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 16681693 163347373 CHEMBL2178580 ZINC43152077 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971369 CC[N+]1(CC2CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C29H36Cl2N2O2/c1-2-33(19-20-7-5-3-4-6-8-20)15-13-23(14-16-33)32-29(34)28-24-17-21(30)9-11-26(24)35-27-12-10-22(31)18-25(27)28/h9-12,17-18,20,23,28H,2-8,13-16,19H2,1H3/p+1 ZTXGBIXSMSZDOC-UHFFFAOYSA-O 50398350 CHEMBL486030::UCB-35625 C-C chemokine receptor type 3 Homo sapiens 93.7 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398350&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search UCB 44560289 163347374 CHEMBL486030 ZINC45484047 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50971371 Clc1ccc(CN2CCC(CC2)NC(=O)CSc2nc3ccccc3s2)cc1Cl InChI=1S/C21H21Cl2N3OS2/c22-16-6-5-14(11-17(16)23)12-26-9-7-15(8-10-26)24-20(27)13-28-21-25-18-3-1-2-4-19(18)29-21/h1-6,11,15H,7-10,12-13H2,(H,24,27) BFHKONATEMTJLB-UHFFFAOYSA-N 50099480 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide::CHEMBL20532 C-C chemokine receptor type 3 Homo sapiens 32 ChEMBL 10.1021/jm300682j 10.7270/Q2862HKR 22931505 Pease, J; Horuk, R National Heart and Lung Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099480&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11037958 103996351 CHEMBL20532 ZINC28232602 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980955 Cn1cc(C(=O)NC[C@@H](O)CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)c(cc1=O)C(F)(F)F InChI=1S/C22H24Cl2F3N3O4/c1-29-12-16(17(9-20(29)32)22(25,26)27)21(33)28-10-13(31)11-30-6-4-14(5-7-30)34-15-2-3-18(23)19(24)8-15/h2-3,8-9,12-14,31H,4-7,10-11H2,1H3,(H,28,33)/t13-/m1/s1 FLTAIVXWWOKLBO-CYBMUJFWSA-N 50402132 CHEMBL2207665 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402132&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71454296 163351156 CHEMBL2207665 ZINC95561837 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980956 Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)c3c[nH]c(=O)cc3C(F)(F)F)CC2)c1Cl InChI=1S/C22H24Cl2F3N3O4/c1-12-17(23)2-3-18(20(12)24)34-14-4-6-30(7-5-14)11-13(31)9-29-21(33)15-10-28-19(32)8-16(15)22(25,26)27/h2-3,8,10,13-14,31H,4-7,9,11H2,1H3,(H,28,32)(H,29,33)/t13-/m1/s1 DLONTNINHYMHFB-CYBMUJFWSA-N 50402133 CHEMBL2207664 C-C chemokine receptor type 3 Homo sapiens 1.26 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402133&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295938 163351157 CHEMBL2207664 ZINC95558653 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980957 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 InChI=1S/C22H25ClF3N3O4/c1-13-8-14(23)2-3-19(13)33-16-4-6-29(7-5-16)12-15(30)10-28-21(32)17-11-27-20(31)9-18(17)22(24,25)26/h2-3,8-9,11,15-16,30H,4-7,10,12H2,1H3,(H,27,31)(H,28,32)/t15-/m1/s1 ODKRBJGIPOQDPJ-OAHLLOKOSA-N 50402107 CHEMBL2207663 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402107&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296066 163351131 CHEMBL2207663 ZINC95560519 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980958 O[C@H](CNC(=O)c1c[nH]c(=O)cc1C(F)(F)F)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C21H22Cl2F3N3O4/c22-17-2-1-14(7-18(17)23)33-13-3-5-29(6-4-13)11-12(30)9-28-20(32)15-10-27-19(31)8-16(15)21(24,25)26/h1-2,7-8,10,12-13,30H,3-6,9,11H2,(H,27,31)(H,28,32)/t12-/m1/s1 SKXJKSJHHFLVAP-GFCCVEGCSA-N 50402108 CHEMBL2207662 C-C chemokine receptor type 3 Homo sapiens 3.16 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402108&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296090 163351132 CHEMBL2207662 ZINC95561933 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980959 O[C@H](CNC(=O)c1cn[nH]c1C1CC1)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C21H26Cl2N4O3/c22-18-4-3-16(9-19(18)23)30-15-5-7-27(8-6-15)12-14(28)10-24-21(29)17-11-25-26-20(17)13-1-2-13/h3-4,9,11,13-15,28H,1-2,5-8,10,12H2,(H,24,29)(H,25,26)/t14-/m1/s1 NDXPOARUSJMOJN-CQSZACIVSA-N 50402134 CHEMBL2207661 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402134&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71459762 163351158 CHEMBL2207661 ZINC95562101 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980960 Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)c3cn[nH]c3C(F)(F)F)CC2)c1Cl InChI=1S/C20H23Cl2F3N4O3/c1-11-15(21)2-3-16(17(11)22)32-13-4-6-29(7-5-13)10-12(30)8-26-19(31)14-9-27-28-18(14)20(23,24)25/h2-3,9,12-13,30H,4-8,10H2,1H3,(H,26,31)(H,27,28)/t12-/m1/s1 IBTMKWBYOYIWBF-GFCCVEGCSA-N 50402135 CHEMBL2207660 C-C chemokine receptor type 3 Homo sapiens 0.794 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402135&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296099 163351159 CHEMBL2207660 ZINC95562951 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980961 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2cn[nH]c2C(F)(F)F)CC1 InChI=1S/C20H24ClF3N4O3/c1-12-8-13(21)2-3-17(12)31-15-4-6-28(7-5-15)11-14(29)9-25-19(30)16-10-26-27-18(16)20(22,23)24/h2-3,8,10,14-15,29H,4-7,9,11H2,1H3,(H,25,30)(H,26,27)/t14-/m1/s1 LSHDMKHXFDYKLP-CQSZACIVSA-N 50402109 CHEMBL2207659 C-C chemokine receptor type 3 Homo sapiens 3.16 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402109&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296100 163351133 CHEMBL2207659 ZINC95558186 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980962 O[C@H](CNC(=O)c1cn[nH]c1C(F)(F)F)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C19H21Cl2F3N4O3/c20-15-2-1-13(7-16(15)21)31-12-3-5-28(6-4-12)10-11(29)8-25-18(30)14-9-26-27-17(14)19(22,23)24/h1-2,7,9,11-12,29H,3-6,8,10H2,(H,25,30)(H,26,27)/t11-/m1/s1 IGYNNXYCDMNULT-LLVKDONJSA-N 50402110 CHEMBL2207658 C-C chemokine receptor type 3 Homo sapiens 6.31 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402110&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296111 163351134 CHEMBL2207658 ZINC95561471 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980963 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3c(F)cccc23)CC1 InChI=1S/C25H27ClFN3O4/c1-15-11-16(26)5-6-22(15)34-18-7-9-30(10-8-18)14-17(31)12-28-24(32)20-13-29-25(33)23-19(20)3-2-4-21(23)27/h2-6,11,13,17-18,31H,7-10,12,14H2,1H3,(H,28,32)(H,29,33)/t17-/m1/s1 GWVFJNPANMKQSY-QGZVFWFLSA-N 50402111 CHEMBL2207657 C-C chemokine receptor type 3 Homo sapiens 0.794 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402111&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295968 163351135 CHEMBL2207657 ZINC95557856 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980964 O[C@H](CNC(=O)c1c[nH]c(=O)c2c(F)cccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H24Cl2FN3O4/c25-19-5-4-16(10-20(19)26)34-15-6-8-30(9-7-15)13-14(31)11-28-23(32)18-12-29-24(33)22-17(18)2-1-3-21(22)27/h1-5,10,12,14-15,31H,6-9,11,13H2,(H,28,32)(H,29,33)/t14-/m1/s1 SUYKBMCECCINPJ-CQSZACIVSA-N 50402112 CHEMBL2207656 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402112&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295978 163351136 CHEMBL2207656 ZINC95562567 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980965 CC1(O)CN(C1)S(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C28H32Cl2N4O7S/c1-28(38)15-34(16-28)42(39,40)20-3-4-21-22(11-20)26(36)32-13-23(21)27(37)31-12-17(35)14-33-8-6-18(7-9-33)41-19-2-5-24(29)25(30)10-19/h2-5,10-11,13,17-18,35,38H,6-9,12,14-16H2,1H3,(H,31,37)(H,32,36)/t17-/m1/s1 QQODNMGQNZBOAF-QGZVFWFLSA-N 50402113 CHEMBL2207655 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402113&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295914 163351137 CHEMBL2207655 ZINC95562162 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980966 O[C@H](CNC(=O)c1c[nH]c(=O)c2cc(ccc12)S(=O)(=O)N1CCC1)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C27H30Cl2N4O6S/c28-24-5-2-19(12-25(24)29)39-18-6-10-32(11-7-18)16-17(34)14-30-27(36)23-15-31-26(35)22-13-20(3-4-21(22)23)40(37,38)33-8-1-9-33/h2-5,12-13,15,17-18,34H,1,6-11,14,16H2,(H,30,36)(H,31,35)/t17-/m1/s1 NZFSPDVTABQASR-QGZVFWFLSA-N 50402114 CHEMBL2207654 C-C chemokine receptor type 3 Homo sapiens 0.316 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402114&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296081 163351138 CHEMBL2207654 ZINC03916653 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980967 CN(C)S(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C26H30Cl2N4O6S/c1-31(2)39(36,37)19-4-5-20-21(12-19)25(34)30-14-22(20)26(35)29-13-16(33)15-32-9-7-17(8-10-32)38-18-3-6-23(27)24(28)11-18/h3-6,11-12,14,16-17,33H,7-10,13,15H2,1-2H3,(H,29,35)(H,30,34)/t16-/m1/s1 JPDUMUHTXIBGHJ-MRXNPFEDSA-N 50402115 CHEMBL2207286 C-C chemokine receptor type 3 Homo sapiens 0.794 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402115&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296033 163351139 CHEMBL2207286 ZINC95561690 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980968 O[C@H](CNC(=O)c1c[nH]c(=O)c2cc(ccc12)S(=O)(=O)NC1CC1)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C27H30Cl2N4O6S/c28-24-6-3-19(11-25(24)29)39-18-7-9-33(10-8-18)15-17(34)13-30-27(36)23-14-31-26(35)22-12-20(4-5-21(22)23)40(37,38)32-16-1-2-16/h3-6,11-12,14,16-18,32,34H,1-2,7-10,13,15H2,(H,30,36)(H,31,35)/t17-/m1/s1 DTYDZUZTWZDAGL-QGZVFWFLSA-N 50402116 CHEMBL2207285 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402116&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295969 163351140 CHEMBL2207285 ZINC95559758 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980969 CNS(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H28Cl2N4O6S/c1-28-38(35,36)18-3-4-19-20(11-18)24(33)30-13-21(19)25(34)29-12-15(32)14-31-8-6-16(7-9-31)37-17-2-5-22(26)23(27)10-17/h2-5,10-11,13,15-16,28,32H,6-9,12,14H2,1H3,(H,29,34)(H,30,33)/t15-/m1/s1 AMEQLQYPRVOFMB-OAHLLOKOSA-N 50402117 CHEMBL2207284 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402117&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296048 163351141 CHEMBL2207284 ZINC95558134 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980970 Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)c3c[nH]c(=O)c4ccc(cc34)S(C)(=O)=O)CC2)c1Cl InChI=1S/C26H29Cl2N3O6S/c1-15-22(27)5-6-23(24(15)28)37-17-7-9-31(10-8-17)14-16(32)12-29-26(34)21-13-30-25(33)19-4-3-18(11-20(19)21)38(2,35)36/h3-6,11,13,16-17,32H,7-10,12,14H2,1-2H3,(H,29,34)(H,30,33)/t16-/m1/s1 YMYZSITWBGWUAF-MRXNPFEDSA-N 50402118 CHEMBL2207283 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402118&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295928 163351142 CHEMBL2207283 ZINC95559830 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980971 NS(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H26Cl2N4O6S/c25-21-4-1-16(9-22(21)26)36-15-5-7-30(8-6-15)13-14(31)11-28-24(33)20-12-29-23(32)19-10-17(37(27,34)35)2-3-18(19)20/h1-4,9-10,12,14-15,31H,5-8,11,13H2,(H,28,33)(H,29,32)(H2,27,34,35)/t14-/m1/s1 MUPZZNZQFUCJBT-CQSZACIVSA-N 50402119 CHEMBL2207282 C-C chemokine receptor type 3 Homo sapiens 25.12 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402119&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295982 163351143 CHEMBL2207282 ZINC95563259 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980972 OCCNS(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C26H30Cl2N4O7S/c27-23-4-1-18(11-24(23)28)39-17-5-8-32(9-6-17)15-16(34)13-29-26(36)22-14-30-25(35)21-12-19(2-3-20(21)22)40(37,38)31-7-10-33/h1-4,11-12,14,16-17,31,33-34H,5-10,13,15H2,(H,29,36)(H,30,35)/t16-/m1/s1 YEGSREZTMOWGTG-MRXNPFEDSA-N 50402120 CHEMBL2207281 C-C chemokine receptor type 3 Homo sapiens 10 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402120&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295946 163351144 CHEMBL2207281 ZINC95564332 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980973 O[C@H](CNC(=O)c1c[nH]c(=O)c2ccc(F)cc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H24Cl2FN3O4/c25-21-4-2-17(10-22(21)26)34-16-5-7-30(8-6-16)13-15(31)11-28-24(33)20-12-29-23(32)18-3-1-14(27)9-19(18)20/h1-4,9-10,12,15-16,31H,5-8,11,13H2,(H,28,33)(H,29,32)/t15-/m1/s1 RMQXJQUUIKBXMM-OAHLLOKOSA-N 50402121 CHEMBL2207280 C-C chemokine receptor type 3 Homo sapiens 3.16 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402121&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295958 163351145 CHEMBL2207280 ZINC95563096 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980974 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3cc(F)ccc23)CC1 InChI=1S/C25H27ClFN3O4/c1-15-10-16(26)2-5-23(15)34-19-6-8-30(9-7-19)14-18(31)12-28-25(33)22-13-29-24(32)21-11-17(27)3-4-20(21)22/h2-5,10-11,13,18-19,31H,6-9,12,14H2,1H3,(H,28,33)(H,29,32)/t18-/m1/s1 IKBGPCPPFWCFRO-GOSISDBHSA-N 50402122 CHEMBL2207279 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402122&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295984 163351146 CHEMBL2207279 ZINC95558918 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980975 O[C@H](CNC(=O)c1c[nH]c(=O)c2cc(F)ccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H24Cl2FN3O4/c25-21-4-2-17(10-22(21)26)34-16-5-7-30(8-6-16)13-15(31)11-28-24(33)20-12-29-23(32)19-9-14(27)1-3-18(19)20/h1-4,9-10,12,15-16,31H,5-8,11,13H2,(H,28,33)(H,29,32)/t15-/m1/s1 DREBLEJJYUKNLT-OAHLLOKOSA-N 50402123 CHEMBL2207278 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402123&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295935 163351147 CHEMBL2207278 ZINC95563976 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980976 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3ccc(cc23)S(C)(=O)=O)CC1 InChI=1S/C26H30ClN3O6S/c1-16-11-17(27)3-6-24(16)36-19-7-9-30(10-8-19)15-18(31)13-28-26(33)23-14-29-25(32)21-5-4-20(12-22(21)23)37(2,34)35/h3-6,11-12,14,18-19,31H,7-10,13,15H2,1-2H3,(H,28,33)(H,29,32)/t18-/m1/s1 GJJRSPSNZFRQIQ-GOSISDBHSA-N 50402124 CHEMBL2207277 C-C chemokine receptor type 3 Homo sapiens 6.31 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402124&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296024 163351148 CHEMBL2207277 ZINC95560904 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980977 Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3cc(ccc23)S(C)(=O)=O)CC1 InChI=1S/C26H30ClN3O6S/c1-16-11-17(27)3-6-24(16)36-19-7-9-30(10-8-19)15-18(31)13-28-26(33)23-14-29-25(32)22-12-20(37(2,34)35)4-5-21(22)23/h3-6,11-12,14,18-19,31H,7-10,13,15H2,1-2H3,(H,28,33)(H,29,32)/t18-/m1/s1 FEIOPVQTLJUJBR-GOSISDBHSA-N 50402125 CHEMBL2207276 C-C chemokine receptor type 3 Homo sapiens 15.85 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402125&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296077 163351149 CHEMBL2207276 ZINC95563716 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980978 Cc1c(Cl)ccc(OC2CCN(C[C@H](O)CNC(=O)c3c[nH]c(=O)c4cc(ccc34)S(C)(=O)=O)CC2)c1Cl InChI=1S/C26H29Cl2N3O6S/c1-15-22(27)5-6-23(24(15)28)37-17-7-9-31(10-8-17)14-16(32)12-29-26(34)21-13-30-25(33)20-11-18(38(2,35)36)3-4-19(20)21/h3-6,11,13,16-17,32H,7-10,12,14H2,1-2H3,(H,29,34)(H,30,33)/t16-/m1/s1 LQCZDIMQFUOGJG-MRXNPFEDSA-N 50402126 CHEMBL2207672 C-C chemokine receptor type 3 Homo sapiens 2.51 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402126&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295974 163351150 CHEMBL2207672 ZINC95562747 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980979 CS(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H27Cl2N3O6S/c1-37(34,35)18-3-4-19-20(11-18)24(32)29-13-21(19)25(33)28-12-15(31)14-30-8-6-16(7-9-30)36-17-2-5-22(26)23(27)10-17/h2-5,10-11,13,15-16,31H,6-9,12,14H2,1H3,(H,28,33)(H,29,32)/t15-/m1/s1 YGYJEYXHZXOPGM-OAHLLOKOSA-N 50402127 CHEMBL2207671 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402127&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295925 163351151 CHEMBL2207671 ZINC95562183 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980980 CS(=O)(=O)c1ccc2c(c[nH]c(=O)c2c1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(C#N)c(Cl)c1 InChI=1S/C26H27ClN4O6S/c1-38(35,36)20-4-5-21-22(11-20)25(33)30-14-23(21)26(34)29-13-17(32)15-31-8-6-18(7-9-31)37-19-3-2-16(12-28)24(27)10-19/h2-5,10-11,14,17-18,32H,6-9,13,15H2,1H3,(H,29,34)(H,30,33)/t17-/m1/s1 MBMAQWYADJFPMU-QGZVFWFLSA-N 50402128 CHEMBL2207670 C-C chemokine receptor type 3 Homo sapiens 63.1 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402128&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296041 163351152 CHEMBL2207670 ZINC95559778 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980981 O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(C#N)c(Cl)c1 InChI=1S/C25H25ClN4O4/c26-23-11-19(6-5-16(23)12-27)34-18-7-9-30(10-8-18)15-17(31)13-28-25(33)22-14-29-24(32)21-4-2-1-3-20(21)22/h1-6,11,14,17-18,31H,7-10,13,15H2,(H,28,33)(H,29,32)/t17-/m1/s1 PREVLKLSVWYCAY-QGZVFWFLSA-N 50402129 CHEMBL2207669 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402129&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296094 163351153 CHEMBL2207669 ZINC95562249 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980982 O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(cc1)C#N InChI=1S/C25H26N4O4/c26-13-17-5-7-19(8-6-17)33-20-9-11-29(12-10-20)16-18(30)14-27-25(32)23-15-28-24(31)22-4-2-1-3-21(22)23/h1-8,15,18,20,30H,9-12,14,16H2,(H,27,32)(H,28,31)/t18-/m1/s1 KLPJSXVRXSMWBK-GOSISDBHSA-N 50402130 CHEMBL2207668 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402130&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296098 163351154 CHEMBL2207668 ZINC95561402 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50980983 NC(=O)c1c(Cl)c(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3ccccc23)CC1 InChI=1S/C25H26Cl2N4O5/c26-19-5-6-20(21(22(19)27)23(28)33)36-15-7-9-31(10-8-15)13-14(32)11-29-25(35)18-12-30-24(34)17-4-2-1-3-16(17)18/h1-6,12,14-15,32H,7-11,13H2,(H2,28,33)(H,29,35)(H,30,34)/t14-/m1/s1 MHAQTEBGBYFXKL-CQSZACIVSA-N 50402131 CHEMBL2207667 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402131&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295960 163351155 CHEMBL2207667 ZINC95563217 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50981015 O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H25Cl2N3O4/c25-21-6-5-17(11-22(21)26)33-16-7-9-29(10-8-16)14-15(30)12-27-24(32)20-13-28-23(31)19-4-2-1-3-18(19)20/h1-6,11,13,15-16,30H,7-10,12,14H2,(H,27,32)(H,28,31)/t15-/m1/s1 YSQQOGOBORIIMG-OAHLLOKOSA-N 50402136 CHEMBL2207666 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.09.112 10.7270/Q2JD4XZZ 23116889 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402136&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9870185 163351160 CHEMBL2207666 ZINC03816882 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982303 CS(=O)(=O)c1ccccc1C(=O)NCC(O)CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C23H29Cl2N3O4S/c1-33(31,32)22-5-3-2-4-19(22)23(30)27-14-18(29)13-26-17-8-10-28(11-9-17)15-16-6-7-20(24)21(25)12-16/h2-7,12,17-18,26,29H,8-11,13-15H2,1H3,(H,27,30) KXSMUDWNWWFRRE-UHFFFAOYSA-N 50402805 CHEMBL2208437 C-C chemokine receptor type 3 Homo sapiens 79.43 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402805&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71461541 163351829 CHEMBL2208437 ZINC95557815 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982305 OC(COc1ccccc1NC(=O)C1CCC1)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C25H30Cl2N2O4/c26-21-9-8-20(14-22(21)27)33-19-10-12-29(13-11-19)15-18(30)16-32-24-7-2-1-6-23(24)28-25(31)17-4-3-5-17/h1-2,6-9,14,17-19,30H,3-5,10-13,15-16H2,(H,28,31) FAPBWZUNGKHHJO-UHFFFAOYSA-N 50402807 CHEMBL2208416 C-C chemokine receptor type 3 Homo sapiens 100 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402807&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10300214 163351831 CHEMBL2208416 ZINC38473705 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982306 COc1cccc(SC[C@@H](O)CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)c1 InChI=1S/C21H25Cl2NO3S/c1-26-17-3-2-4-19(11-17)28-14-15(25)13-24-9-7-16(8-10-24)27-18-5-6-20(22)21(23)12-18/h2-6,11-12,15-16,25H,7-10,13-14H2,1H3/t15-/m0/s1 VDFDTTRCUDMUDX-HNNXBMFYSA-N 50402808 CHEMBL2208421 C-C chemokine receptor type 3 Homo sapiens 125.89 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402808&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71463288 163351832 CHEMBL2208421 ZINC95558680 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982307 O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1ccc(cc1)C#N InChI=1S/C22H25Cl2N3O2/c23-21-6-3-17(11-22(21)24)14-27-9-7-18(8-10-27)26-13-19(28)15-29-20-4-1-16(12-25)2-5-20/h1-6,11,18-19,26,28H,7-10,13-15H2/t19-/m0/s1 KOACYGPEOVSJCA-IBGZPJMESA-N 50402809 CHEMBL2208417 C-C chemokine receptor type 3 Homo sapiens 125.89 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402809&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71459825 163351833 CHEMBL2208417 ZINC95562237 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982308 O[C@H](CNS(=O)(=O)c1cccc(c1)C#N)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C21H23Cl2N3O4S/c22-20-5-4-18(11-21(20)23)30-17-6-8-26(9-7-17)14-16(27)13-25-31(28,29)19-3-1-2-15(10-19)12-24/h1-5,10-11,16-17,25,27H,6-9,13-14H2/t16-/m1/s1 RHDOFWFMSRHNFN-MRXNPFEDSA-N 50402804 CHEMBL2208422 C-C chemokine receptor type 3 Homo sapiens 158.49 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402804&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296073 163351828 CHEMBL2208422 ZINC95562364 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982309 O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1ccc2ncsc2c1 InChI=1S/C22H25Cl2N3O2S/c23-19-3-1-15(9-20(19)24)12-27-7-5-16(6-8-27)25-11-17(28)13-29-18-2-4-21-22(10-18)30-14-26-21/h1-4,9-10,14,16-17,25,28H,5-8,11-13H2/t17-/m0/s1 MNXRFTOYSSFEST-KRWDZBQOSA-N 50402810 CHEMBL2208418 C-C chemokine receptor type 3 Homo sapiens 158.49 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402810&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71454365 163351834 CHEMBL2208418 ZINC95561789 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50986811 CC(=O)c1cccc(NC(=O)NCCCN2CC3CCC2[C@@H](Cc2ccc(F)cc2)C3)c1 InChI=1S/C26H32FN3O2/c1-18(31)21-4-2-5-24(16-21)29-26(32)28-12-3-13-30-17-20-8-11-25(30)22(15-20)14-19-6-9-23(27)10-7-19/h2,4-7,9-10,16,20,22,25H,3,8,11-15,17H2,1H3,(H2,28,29,32)/t20?,22-,25?/m0/s1 MKZSQKHBMZZFJJ-CVCZCXRASA-N 50404327 CHEMBL2114958 C-C chemokine receptor type 3 Homo sapiens 169 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404327&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71458114 163353351 CHEMBL2114958 ZINC29394027 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50986812 CC(=O)c1cccc(NC(=O)NCCCN2CC3CCC2[C@H](Cc2ccc(F)cc2)C3)c1 InChI=1S/C26H32FN3O2/c1-18(31)21-4-2-5-24(16-21)29-26(32)28-12-3-13-30-17-20-8-11-25(30)22(15-20)14-19-6-9-23(27)10-7-19/h2,4-7,9-10,16,20,22,25H,3,8,11-15,17H2,1H3,(H2,28,29,32)/t20?,22-,25?/m1/s1 MKZSQKHBMZZFJJ-YAQMXYOYSA-N 50404328 CHEMBL2115412 C-C chemokine receptor type 3 Homo sapiens 802 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404328&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71454583 163353352 CHEMBL2115412 ZINC36351997 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982311 O[C@H](CNC(=O)c1cn2cc(F)ccc2n1)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H23Cl2FN4O3/c23-18-3-2-17(9-19(18)24)32-16-5-7-28(8-6-16)12-15(30)10-26-22(31)20-13-29-11-14(25)1-4-21(29)27-20/h1-4,9,11,13,15-16,30H,5-8,10,12H2,(H,26,31)/t15-/m1/s1 PCRWWFINVOSHRN-OAHLLOKOSA-N 50402812 CHEMBL2208425 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402812&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296114 163351836 CHEMBL2208425 ZINC95559753 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982314 CS(=O)(=O)c1ccc(s1)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C20H24Cl2N2O5S2/c1-31(27,28)19-5-4-18(30-19)20(26)23-11-13(25)12-24-8-6-14(7-9-24)29-15-2-3-16(21)17(22)10-15/h2-5,10,13-14,25H,6-9,11-12H2,1H3,(H,23,26)/t13-/m1/s1 AJUWTQZJBKWQNV-CYBMUJFWSA-N 50402806 CHEMBL2208426 C-C chemokine receptor type 3 Homo sapiens 251.19 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402806&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296085 163351830 CHEMBL2208426 ZINC95561946 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982315 O[C@H](COc1cccc(c1)C#N)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C21H22Cl2N2O3/c22-20-5-4-19(11-21(20)23)28-17-6-8-25(9-7-17)13-16(26)14-27-18-3-1-2-15(10-18)12-24/h1-5,10-11,16-17,26H,6-9,13-14H2/t16-/m0/s1 ZOYPHDPQFYRSLG-INIZCTEOSA-N 50402814 CHEMBL2208419 C-C chemokine receptor type 3 Homo sapiens 251.19 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402814&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71463287 163351838 CHEMBL2208419 ZINC95563067 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982317 O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1cccc(c1)C#N InChI=1S/C22H25Cl2N3O2/c23-21-5-4-17(11-22(21)24)14-27-8-6-18(7-9-27)26-13-19(28)15-29-20-3-1-2-16(10-20)12-25/h1-5,10-11,18-19,26,28H,6-9,13-15H2/t19-/m0/s1 DPJWTHMHDTUYEX-IBGZPJMESA-N 50402815 CHEMBL2208436 C-C chemokine receptor type 3 Homo sapiens 316.23 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402815&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71452602 163351839 CHEMBL2208436 ZINC95560186 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982322 Clc1ccc(OC2CCN(CCCOc3cccc(c3)C#N)CC2)cc1Cl InChI=1S/C21H22Cl2N2O2/c22-20-6-5-19(14-21(20)23)27-17-7-10-25(11-8-17)9-2-12-26-18-4-1-3-16(13-18)15-24/h1,3-6,13-14,17H,2,7-12H2 AMQPWRCXJRAWTN-UHFFFAOYSA-N 50402818 CHEMBL2208420 C-C chemokine receptor type 3 Homo sapiens 794.33 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402818&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71450777 163351842 CHEMBL2208420 ZINC95562613 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982334 O[C@H](CNC(=O)c1n[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H24Cl2N4O4/c24-19-6-5-16(11-20(19)25)33-15-7-9-29(10-8-15)13-14(30)12-26-23(32)21-17-3-1-2-4-18(17)22(31)28-27-21/h1-6,11,14-15,30H,7-10,12-13H2,(H,26,32)(H,28,31)/t14-/m1/s1 XBJQRDCFABQBGT-CQSZACIVSA-N 50402816 CHEMBL2208431 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402816&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296010 163351840 CHEMBL2208431 ZINC03816884 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982335 O[C@H](CNC(=O)c1n[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H24Cl2N4O3/c23-18-6-5-16(11-19(18)24)31-15-7-9-28(10-8-15)13-14(29)12-25-22(30)21-17-3-1-2-4-20(17)26-27-21/h1-6,11,14-15,29H,7-10,12-13H2,(H,25,30)(H,26,27)/t14-/m1/s1 RGQXJYRGDMABLT-CQSZACIVSA-N 50402813 CHEMBL2208429 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402813&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295931 163351837 CHEMBL2208429 ZINC95560704 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982336 O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H25Cl2N3O4/c25-21-6-5-17(11-22(21)26)33-16-7-9-29(10-8-16)14-15(30)12-27-24(32)20-13-28-23(31)19-4-2-1-3-18(19)20/h1-6,11,13,15-16,30H,7-10,12,14H2,(H,27,32)(H,28,31)/t15-/m1/s1 YSQQOGOBORIIMG-OAHLLOKOSA-N 50402136 CHEMBL2207666 C-C chemokine receptor type 3 Homo sapiens 1.58 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402136&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9870185 163351160 CHEMBL2207666 ZINC03816882 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982340 CN(C[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1)C(=O)c1c[nH]c(=O)c2ccccc12 InChI=1S/C25H27Cl2N3O4/c1-29(25(33)21-13-28-24(32)20-5-3-2-4-19(20)21)14-16(31)15-30-10-8-17(9-11-30)34-18-6-7-22(26)23(27)12-18/h2-7,12-13,16-17,31H,8-11,14-15H2,1H3,(H,28,32)/t16-/m1/s1 WBCSOAILRDZMDJ-MRXNPFEDSA-N 50402819 CHEMBL2208433 C-C chemokine receptor type 3 Homo sapiens 2.51 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402819&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296104 163351843 CHEMBL2208433 ZINC03816886 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982341 O[C@H](CNC(=O)n1c2ccccc2[nH]c1=O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H24Cl2N4O4/c23-17-6-5-16(11-18(17)24)32-15-7-9-27(10-8-15)13-14(29)12-25-21(30)28-20-4-2-1-3-19(20)26-22(28)31/h1-6,11,14-15,29H,7-10,12-13H2,(H,25,30)(H,26,31)/t14-/m1/s1 CLQMFOOMFPNKNA-CQSZACIVSA-N 50402817 CHEMBL2208432 C-C chemokine receptor type 3 Homo sapiens 2.51 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402817&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296000 163351841 CHEMBL2208432 ZINC95558524 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982342 O[C@H](CNC(=O)c1c[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H25Cl2N3O3/c24-20-6-5-17(11-21(20)25)31-16-7-9-28(10-8-16)14-15(29)12-27-23(30)19-13-26-22-4-2-1-3-18(19)22/h1-6,11,13,15-16,26,29H,7-10,12,14H2,(H,27,30)/t15-/m1/s1 DIXSEWSBXAEKKY-OAHLLOKOSA-N 50402820 CHEMBL2208430 C-C chemokine receptor type 3 Homo sapiens 2.51 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402820&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295939 163351844 CHEMBL2208430 ZINC03816885 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982345 COc1cc(ccc1N)C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H27Cl2N3O4/c1-30-21-10-14(2-5-20(21)25)22(29)26-12-15(28)13-27-8-6-16(7-9-27)31-17-3-4-18(23)19(24)11-17/h2-5,10-11,15-16,28H,6-9,12-13,25H2,1H3,(H,26,29)/t15-/m1/s1 GPRHHSZIXIDKDN-OAHLLOKOSA-N 50402803 CHEMBL2208427 C-C chemokine receptor type 3 Homo sapiens 3.98 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402803&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296039 163351827 CHEMBL2208427 ZINC95561855 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982347 O[C@H](CNC(=O)c1cc(=O)[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C24H25Cl2N3O4/c25-20-6-5-17(11-21(20)26)33-16-7-9-29(10-8-16)14-15(30)13-27-24(32)19-12-23(31)28-22-4-2-1-3-18(19)22/h1-6,11-12,15-16,30H,7-10,13-14H2,(H,27,32)(H,28,31)/t15-/m1/s1 MAWNODXTLNGOAA-OAHLLOKOSA-N 50402822 CHEMBL2208434 C-C chemokine receptor type 3 Homo sapiens 7.94 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402822&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295994 163351846 CHEMBL2208434 ZINC95562981 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982350 O[C@H](CNC(=O)c1cnnc2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C23H24Cl2N4O3/c24-20-6-5-17(11-21(20)25)32-16-7-9-29(10-8-16)14-15(30)12-26-23(31)19-13-27-28-22-4-2-1-3-18(19)22/h1-6,11,13,15-16,30H,7-10,12,14H2,(H,26,31)/t15-/m1/s1 KOUMCBHTVFDPSI-OAHLLOKOSA-N 50402821 CHEMBL2208435 C-C chemokine receptor type 3 Homo sapiens 12.59 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402821&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59295926 163351845 CHEMBL2208435 ZINC95559460 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982353 CS(=O)(=O)c1ccccc1C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H26Cl2N2O5S/c1-32(29,30)21-5-3-2-4-18(21)22(28)25-13-15(27)14-26-10-8-16(9-11-26)31-17-6-7-19(23)20(24)12-17/h2-7,12,15-16,27H,8-11,13-14H2,1H3,(H,25,28)/t15-/m1/s1 JMGBVGDZPLNFAE-OAHLLOKOSA-N 50402811 CHEMBL2208428 C-C chemokine receptor type 3 Homo sapiens 15.85 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402811&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296109 163351835 CHEMBL2208428 ZINC95564113 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982356 O[C@H](CNC(=O)c1cccc(c1)C#N)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 InChI=1S/C22H23Cl2N3O3/c23-20-5-4-19(11-21(20)24)30-18-6-8-27(9-7-18)14-17(28)13-26-22(29)16-3-1-2-15(10-16)12-25/h1-5,10-11,17-18,28H,6-9,13-14H2,(H,26,29)/t17-/m1/s1 PXQMPHKMJWQPRD-QGZVFWFLSA-N 50402824 CHEMBL2208423 C-C chemokine receptor type 3 Homo sapiens 19.95 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402824&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59296064 163351848 CHEMBL2208423 ZINC95564132 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50982357 O[C@@H](CCN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1)COc1cccc(c1)C#N InChI=1S/C22H24Cl2N2O3/c23-21-5-4-20(13-22(21)24)29-18-7-10-26(11-8-18)9-6-17(27)15-28-19-3-1-2-16(12-19)14-25/h1-5,12-13,17-18,27H,6-11,15H2/t17-/m0/s1 IKNJHFAJDYZLNM-KRWDZBQOSA-N 50402823 CHEMBL2208424 C-C chemokine receptor type 3 Homo sapiens 31.62 ChEMBL 10.1016/j.bmcl.2012.09.113 10.7270/Q2CJ8FNG 23142617 Furber, M; Alcaraz, L; Luckhurst, C; Bahl, A; Beaton, H; Bowers, K; Collington, J; Denton, R; Donald, D; Kinchin, E; MacDonald, C; Rigby, A; Riley, R; Soars, M; Springthorpe, B; Webborn, P AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402823&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71452601 163351847 CHEMBL2208424 ZINC95557817 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001152 COc1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCCC(Cc3ccccc3)C2)c1 InChI=1S/C27H37N3O2/c1-32-25-14-7-13-24(18-25)28-27(31)29-26-15-6-5-12-23(26)20-30-16-8-11-22(19-30)17-21-9-3-2-4-10-21/h2-4,7,9-10,13-14,18,22-23,26H,5-6,8,11-12,15-17,19-20H2,1H3,(H2,28,29,31)/t22?,23-,26+/m0/s1 FRDMBUQGNRPFBS-FITRJGIZSA-N 50410313 CHEMBL2112987 C-C chemokine receptor type 3 Homo sapiens 28 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410313&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 71449114 163359337 CHEMBL2112987 ZINC13613223 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001154 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ccc4c3)C2)cc1 InChI=1S/C28H35FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-14,17,21,23,27,30H,1-6,15-16,18-19H2,(H2,31,32,34)/t21-,23-,27+/m0/s1 YHFFIZVSOADVRF-JEYPMZLKSA-N 50410314 CHEMBL2113074 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410314&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11328714 163359338 CHEMBL2113074 ZINC13613312 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001156 COc1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C27H36FN3O2/c1-33-25-9-4-8-24(17-25)29-27(32)30-26-10-3-2-7-22(26)19-31-15-5-6-21(18-31)16-20-11-13-23(28)14-12-20/h4,8-9,11-14,17,21-22,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,29,30,32)/t21-,22-,26+/m0/s1 LGJFJZSNTJWEAX-AOJNWGRGSA-N 50410315 CHEMBL2096763 C-C chemokine receptor type 3 Homo sapiens 14 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410315&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11247999 163359339 CHEMBL2096763 ZINC13613239 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001157 COc1cccc(NC(=O)NC2CCCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C27H36FN3O2/c1-33-26-7-3-6-25(18-26)30-27(32)29-24-5-2-4-22(17-24)19-31-14-12-21(13-15-31)16-20-8-10-23(28)11-9-20/h3,6-11,18,21-22,24H,2,4-5,12-17,19H2,1H3,(H2,29,30,32) JGTFGENGLZWIEQ-UHFFFAOYSA-N 50410316 CHEMBL2112050 C-C chemokine receptor type 3 Homo sapiens 78 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410316&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11385474 163359340 CHEMBL2112050 ZINC13613207 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001158 Fc1ccc(C[C@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3cccc(c3)C#N)C2)cc1 InChI=1S/C27H33FN4O/c28-24-12-10-20(11-13-24)15-22-6-4-14-32(18-22)19-23-7-1-2-9-26(23)31-27(33)30-25-8-3-5-21(16-25)17-29/h3,5,8,10-13,16,22-23,26H,1-2,4,6-7,9,14-15,18-19H2,(H2,30,31,33)/t22-,23+,26-/m1/s1 YYWBSASXGCRFHA-MVERNJQCSA-N 50410317 CHEMBL2096696 C-C chemokine receptor type 3 Homo sapiens 9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410317&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11236236 163359341 CHEMBL2096696 ZINC13613249 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001159 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3cccc(c3)C#N)C2)cc1 InChI=1S/C27H33FN4O/c28-24-12-10-20(11-13-24)15-22-6-4-14-32(18-22)19-23-7-1-2-9-26(23)31-27(33)30-25-8-3-5-21(16-25)17-29/h3,5,8,10-13,16,22-23,26H,1-2,4,6-7,9,14-15,18-19H2,(H2,30,31,33)/t22-,23-,26+/m0/s1 YYWBSASXGCRFHA-JCYRPKCISA-N 50410318 CHEMBL2096764 C-C chemokine receptor type 3 Homo sapiens 9 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410318&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11224689 163359342 CHEMBL2096764 ZINC13613246 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001165 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3cccc(Cl)c3)C2)cc1 InChI=1S/C26H33ClFN3O/c27-22-7-3-8-24(16-22)29-26(32)30-25-9-2-1-6-21(25)18-31-14-4-5-20(17-31)15-19-10-12-23(28)13-11-19/h3,7-8,10-13,16,20-21,25H,1-2,4-6,9,14-15,17-18H2,(H2,29,30,32)/t20-,21-,25+/m0/s1 FVPHCTLIAMZSPI-STWLZBDKSA-N 50410319 CHEMBL2113082 C-C chemokine receptor type 3 Homo sapiens 31 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410319&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11396966 163359343 CHEMBL2113082 ZINC13613280 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001166 CC(=O)c1cccc(NC(=O)NC2CCCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)24-5-3-7-27(18-24)31-28(34)30-26-6-2-4-23(17-26)19-32-14-12-22(13-15-32)16-21-8-10-25(29)11-9-21/h3,5,7-11,18,22-23,26H,2,4,6,12-17,19H2,1H3,(H2,30,31,34) OUKVNSIWECXJGC-UHFFFAOYSA-N 50410320 CHEMBL2112049 C-C chemokine receptor type 3 Homo sapiens 41 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410320&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11282712 163359344 CHEMBL2112049 ZINC13613220 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001167 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4ncsc4c3)C2)cc1 InChI=1S/C27H33FN4OS/c28-22-9-7-19(8-10-22)14-20-4-3-13-32(16-20)17-21-5-1-2-6-24(21)31-27(33)30-23-11-12-25-26(15-23)34-18-29-25/h7-12,15,18,20-21,24H,1-6,13-14,16-17H2,(H2,30,31,33)/t20-,21-,24+/m0/s1 GUTLQOKVJCDGEX-AWRGLXIESA-N 50410321 CHEMBL2113076 C-C chemokine receptor type 3 Homo sapiens 1.2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410321&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11167549 163359345 CHEMBL2113076 ZINC13613331 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001172 CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C28H36FN3O2/c1-20(33)23-8-4-9-26(17-23)30-28(34)31-27-10-3-2-7-24(27)19-32-15-5-6-22(18-32)16-21-11-13-25(29)14-12-21/h4,8-9,11-14,17,22,24,27H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,30,31,34)/t22-,24-,27+/m0/s1 ASRDPULQBHFPGU-WFIHMLKPSA-N 50209971 1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea::CHEMBL250689 C-C chemokine receptor type 3 Homo sapiens 0.039000 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209971&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11227406 104086617 CHEMBL250689 ZINC06716821 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001173 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]nc(Cl)c4c3)C2)cc1 InChI=1S/C27H33ClFN5O/c28-26-23-15-22(11-12-25(23)32-33-26)30-27(35)31-24-6-2-1-5-20(24)17-34-13-3-4-19(16-34)14-18-7-9-21(29)10-8-18/h7-12,15,19-20,24H,1-6,13-14,16-17H2,(H,32,33)(H2,30,31,35)/t19-,20-,24+/m0/s1 RDKJBOCQZSAPSZ-MZLICYQSSA-N 50410323 CHEMBL2113079 C-C chemokine receptor type 3 Homo sapiens 1.3 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410323&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11306550 163359347 CHEMBL2113079 ZINC13613325 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001175 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4[nH]ncc4c3)C2)cc1 InChI=1S/C27H34FN5O/c28-23-9-7-19(8-10-23)14-20-4-3-13-33(17-20)18-21-5-1-2-6-25(21)31-27(34)30-24-11-12-26-22(15-24)16-29-32-26/h7-12,15-16,20-21,25H,1-6,13-14,17-18H2,(H,29,32)(H2,30,31,34)/t20-,21-,25+/m0/s1 MLPROCBAZKTJHS-STWLZBDKSA-N 50410322 CHEMBL2113077 C-C chemokine receptor type 3 Homo sapiens 2 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410322&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11488078 163359346 CHEMBL2113077 ZINC13613319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001176 COc1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@H](Cc3ccc(F)cc3)C2)c1 InChI=1S/C27H36FN3O2/c1-33-25-9-4-8-24(17-25)29-27(32)30-26-10-3-2-7-22(26)19-31-15-5-6-21(18-31)16-20-11-13-23(28)14-12-20/h4,8-9,11-14,17,21-22,26H,2-3,5-7,10,15-16,18-19H2,1H3,(H2,29,30,32)/t21-,22+,26-/m1/s1 LGJFJZSNTJWEAX-TVZXLZGTSA-N 50410324 CHEMBL2096695 C-C chemokine receptor type 3 Homo sapiens 29 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410324&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11408397 163359348 CHEMBL2096695 ZINC13613243 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51001177 Fc1ccc(C[C@@H]2CCCN(C[C@@H]3CCCC[C@H]3NC(=O)Nc3ccc4NCCc4c3)C2)cc1 InChI=1S/C28H37FN4O/c29-24-9-7-20(8-10-24)16-21-4-3-15-33(18-21)19-23-5-1-2-6-27(23)32-28(34)31-25-11-12-26-22(17-25)13-14-30-26/h7-12,17,21,23,27,30H,1-6,13-16,18-19H2,(H2,31,32,34)/t21-,23-,27+/m0/s1 GIEDRDQDSGAHQW-JEYPMZLKSA-N 50410325 CHEMBL2113080 C-C chemokine receptor type 3 Homo sapiens 1.7 ChEMBL 10.1021/jm049530m 10.7270/Q2XP74F1 15771462 De Lucca, GV; Kim, UT; Vargo, BJ; Duncia, JV; Santella, JB; Gardner, DS; Zheng, C; Liauw, A; Wang, Z; Emmett, G; Wacker, DA; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Das, AM; Davies, P; Yeleswaram, S; Graden, DM; Solomon, KA; Newton, RC; Trainor, GL; Decicco, CP; Ko, SS Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410325&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 11751629 163359349 CHEMBL2113080 ZINC13613328 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51000271 Nc1n2CCC(=Cc3ccccc3Br)c2nc2ncnc12 InChI=1S/C15H12BrN5/c16-11-4-2-1-3-9(11)7-10-5-6-21-13(17)12-14(19-8-18-12)20-15(10)21/h1-4,7-8H,5-6,17H2 AXKVEIJEJWDHIT-UHFFFAOYSA-N 50410084 CHEMBL2113024 C-C chemokine receptor type 3 Homo sapiens 830 ChEMBL 10.1016/j.bmcl.2004.11.039 10.7270/Q2NV9HS2 15664834 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhauser, G; Birke, FW Boehringer Ingelheim Pharma GmbH and Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50410084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50410084&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68634275 163359108 CHEMBL2113024 ZINC95607637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50998208 [I-].CC[N+]1(C\C2=C\CCCCCC2)CC[C@@H](CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 InChI=1S/C30H36Cl2N2O2.HI/c1-2-34(20-21-8-6-4-3-5-7-9-21)16-14-24(15-17-34)33-30(35)29-25-18-22(31)10-12-27(25)36-28-13-11-23(32)19-26(28)29;/h8,10-13,18-19,24,29H,2-7,9,14-17,20H2,1H3;1H/b21-8+;/t24-,34?; FOAFBMYSXIGAOX-CJCAHDPRSA-N 50098624 1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthene-9-carbonyl)-amino]-1-ethyl-piperidinium; iodide::CHEMBL34626 C-C chemokine receptor type 3 Homo sapiens 0.580000 ChEMBL 10.1021/jm0004244 10.7270/Q2G73D0G 11311066 Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098624&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 6918496 103995616 CHEMBL34626 ZINC13862637 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50027522 CC(=O)c1cccc(NC(=O)NCCCN2[C@H]3CC[C@@H]2C[C@H](Cc2ccc(F)cc2)C3)c1 InChI=1S/C26H32FN3O2/c1-18(31)21-4-2-5-23(17-21)29-26(32)28-12-3-13-30-24-10-11-25(30)16-20(15-24)14-19-6-8-22(27)9-7-19/h2,4-9,17,20,24-25H,3,10-16H2,1H3,(H2,28,29,32)/t20-,24+,25- XSCFHQOTZLKNDH-BBEFWCPCSA-N 50142460 1-(3-Acetyl-phenyl)-3-{3-[3-(4-fluoro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-urea::CHEMBL3085118 C-C chemokine receptor type 3 Homo sapiens 7.4 ChEMBL 10.1016/j.bmcl.2004.01.059 10.7270/Q2RB741N 15026042 Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142460&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68826395 104031841 CHEMBL3085118 ZINC29399998 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014056 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 35 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014058 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 35.0 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014059 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 38 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014060 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 7 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50014061 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 5 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180450 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 32.0 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50583350 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 32 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50583351 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 25.0 ChEMBL 10.1016/s0960-894x(01)00248-7 10.7270/Q27D2TD0 11378373 Dhanak, D; Christmann, LT; Darcy, MG; Jurewicz, AJ; Keenan, RM; Lee, J; Sarau, HM; Widdowson, KL; White, JR SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50180481 CCn1ccnc1[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C24H22N4O3/c1-2-27-15-14-25-23(27)22(16-17-10-12-19(13-11-17)28(30)31)26-24(29)21-9-5-7-18-6-3-4-8-20(18)21/h3-15,22H,2,16H2,1H3,(H,26,29)/t22-/m0/s1 SPCKTJSHKWCWJB-QFIPXVFZSA-N 50100056 CHEMBL287538::Naphthalene-1-carboxylic acid [(S)-1-(1-ethyl-1H-imidazol-2-yl)-2-(4-nitro-phenyl)-ethyl]-amide C-C chemokine receptor type 3 Homo sapiens >33000 ChEMBL 10.1016/s0960-894x(01)00249-9 10.7270/Q23N22N6 11378374 Dhanak, D; Christmann, LT; Darcy, MG; Keenan, RM; Knight, SD; Lee, J; Ridgers, LH; Sarau, HM; Shah, DH; White, JR; Zhang, L SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100056&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44281793 103996872 CHEMBL287538 ZINC29231833 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50528193 COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1cc(OC)c(O)c(OC)c1 InChI=1S/C21H24O5/c1-6-7-13-8-15-12(2)20(26-21(15)18(9-13)25-5)14-10-16(23-3)19(22)17(11-14)24-4/h6-12,20,22H,1-5H3/b7-6+/t12-,20-/m1/s1 LYZVPGMCGPXCQO-FVFSBHJXSA-N 50202469 CHEMBL3906647 C-C chemokine receptor type 3 Homo sapiens 1600 ChEMBL 10.1021/acs.jnatprod.6b00262 10.7270/Q2MW2K39 27419473 Morikawa, T; Hachiman, I; Matsuo, K; Nishida, E; Ninomiya, K; Hayakawa, T; Yoshie, O; Muraoka, O; Nakayama, T Kindai University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202469&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 124396489 375979674 CHEMBL3906647 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50528194 COc1ccc(cc1OC)[C@@H](OC(C)=O)[C@H](C)Oc1c(OC)cc(CC=C)cc1OC InChI=1S/C24H30O7/c1-8-9-17-12-21(28-6)24(22(13-17)29-7)30-15(2)23(31-16(3)25)18-10-11-19(26-4)20(14-18)27-5/h8,10-15,23H,1,9H2,2-7H3/t15-,23-/m0/s1 SITDJJDXDVFCAP-WNSKOXEYSA-N 50202470 CHEMBL3922119 C-C chemokine receptor type 3 Homo sapiens 1400 ChEMBL 10.1021/acs.jnatprod.6b00262 10.7270/Q2MW2K39 27419473 Morikawa, T; Hachiman, I; Matsuo, K; Nishida, E; Ninomiya, K; Hayakawa, T; Yoshie, O; Muraoka, O; Nakayama, T Kindai University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202470&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 38347547 375979675 CHEMBL3922119 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50528195 COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12 InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1 VMFGCGRAIBLAFY-IBGZPJMESA-N 50100021 (S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-phenyl)-propionic acid methyl ester::CHEMBL33227 C-C chemokine receptor type 3 Homo sapiens 780 ChEMBL 10.1021/acs.jnatprod.6b00262 10.7270/Q2MW2K39 27419473 Morikawa, T; Hachiman, I; Matsuo, K; Nishida, E; Ninomiya, K; Hayakawa, T; Yoshie, O; Muraoka, O; Nakayama, T Kindai University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 10474776 103996837 CHEMBL33227 ZINC29222893 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50528196 COc1cc(cc(OC)c1O)[C@H](O)[C@@H](C)Oc1c(OC)cc(CC=C)cc1OC InChI=1S/C22H28O7/c1-7-8-14-9-18(27-5)22(19(10-14)28-6)29-13(2)20(23)15-11-16(25-3)21(24)17(12-15)26-4/h7,9-13,20,23-24H,1,8H2,2-6H3/t13-,20-/m1/s1 JJVOBQHHQSQIMW-ZUOKHONESA-N 50202471 CHEMBL3949874 C-C chemokine receptor type 3 Homo sapiens 1500 ChEMBL 10.1021/acs.jnatprod.6b00262 10.7270/Q2MW2K39 27419473 Morikawa, T; Hachiman, I; Matsuo, K; Nishida, E; Ninomiya, K; Hayakawa, T; Yoshie, O; Muraoka, O; Nakayama, T Kindai University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202471&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 25751147 375979676 CHEMBL3949874 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016797 COc1cccc(NC(=O)N2CCNC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H33FN4O2/c1-32-24-4-2-3-22(16-24)28-25(31)30-14-11-27-23(18-30)17-29-12-9-20(10-13-29)15-19-5-7-21(26)8-6-19/h2-8,16,20,23,27H,9-15,17-18H2,1H3,(H,28,31) MYEGDSXUBNEVSB-UHFFFAOYSA-N 50115015 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperazine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL54273 C-C chemokine receptor type 3 Homo sapiens 140 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115015&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509697 104009003 CHEMBL54273 ZINC22924703 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016799 COc1cccc(NC(=O)N2CCOC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C25H32FN3O3/c1-31-23-4-2-3-22(16-23)27-25(30)29-13-14-32-24(18-29)17-28-11-9-20(10-12-28)15-19-5-7-21(26)8-6-19/h2-8,16,20,24H,9-15,17-18H2,1H3,(H,27,30) CBNWNPGNUKPULD-UHFFFAOYSA-N 50115053 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-morpholine-4-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL51584 C-C chemokine receptor type 3 Homo sapiens 220 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115053&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509695 104009041 CHEMBL51584 ZINC13443618 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016804 CC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O3/c1-3-26(32)25-18-22(17-21-9-5-4-6-10-21)13-16-30(25)15-8-14-28-27(33)29-24-12-7-11-23(19-24)20(2)31/h4-7,9-12,19,22,25-26,32H,3,8,13-18H2,1-2H3,(H2,28,29,33)/t22-,25-,26+/m1/s1 UEKNCACYTQCRSI-RCXJIHSJSA-N 50115012 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50593 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115012&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9868459 104009000 CHEMBL50593 3492 ZINC13443656 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50016807 CCC[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O2/c1-3-9-26-19-23(18-22-10-5-4-6-11-22)14-17-30(26)16-8-15-28-27(32)29-25-13-7-12-24(20-25)21(2)31/h4-7,10-13,20,23,26H,3,8-9,14-19H2,1-2H3,(H2,28,29,32)/t23-,26+/m1/s1 LSVGDBOAFGMALQ-BVAGGSTKSA-N 50115037 1-(3-Acetyl-phenyl)-3-[3-((2S,4S)-4-benzyl-2-propyl-piperidin-1-yl)-propyl]-urea::CHEMBL50423 C-C chemokine receptor type 3 Homo sapiens 100.0 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115037&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295664 104009025 CHEMBL50423 ZINC13443638 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208188 CCCC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C29H41N3O3/c1-3-4-14-28(34)27-20-24(19-23-10-6-5-7-11-23)15-18-32(27)17-9-16-30-29(35)31-26-13-8-12-25(21-26)22(2)33/h5-8,10-13,21,24,27-28,34H,3-4,9,14-20H2,1-2H3,(H2,30,31,35)/t24-,27-,28+/m1/s1 UIBIFUUBDLVHTJ-RTVRTQBESA-N 50115047 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-pentyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50233 C-C chemokine receptor type 3 Homo sapiens 1 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115047&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295536 104009035 CHEMBL50233 ZINC13443681 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208191 COc1cccc(NC(=O)N2CCN(C(CN3CCC(Cc4ccc(F)cc4)CC3)C2)C(=O)OC(C)(C)C)c1 InChI=1S/C30H41FN4O4/c1-30(2,3)39-29(37)35-17-16-34(28(36)32-25-6-5-7-27(19-25)38-4)21-26(35)20-33-14-12-23(13-15-33)18-22-8-10-24(31)11-9-22/h5-11,19,23,26H,12-18,20-21H2,1-4H3,(H,32,36) BYJSSJUUKGUDHW-UHFFFAOYSA-N 50115081 2-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-4-(3-methoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL51937 C-C chemokine receptor type 3 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 23509693 104009069 CHEMBL51937 ZINC13443629 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208198 Clc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C23H27ClN4O/c24-21-7-5-18(6-8-21)15-19-9-13-28(14-10-19)12-2-11-26-23(29)27-22-4-1-3-20(16-22)17-25/h1,3-8,16,19H,2,9-15H2,(H2,26,27,29) QPYSQIOCOXFUJE-UHFFFAOYSA-N 50115031 1-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-propyl}-3-(3-cyano-phenyl)-urea::CHEMBL48873 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115031&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393339 104009019 CHEMBL48873 ZINC13443557 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208226 COc1cccc(NC(=O)N2CCCC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 InChI=1S/C26H34FN3O2/c1-32-25-6-2-5-24(17-25)28-26(31)30-13-3-4-22(19-30)18-29-14-11-21(12-15-29)16-20-7-9-23(27)10-8-20/h2,5-10,17,21-22H,3-4,11-16,18-19H2,1H3,(H,28,31) ONWGMJQANDWQQF-UHFFFAOYSA-N 50115082 3-[4-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-piperidine-1-carboxylic acid (3-methoxy-phenyl)-amide::CHEMBL50535 C-C chemokine receptor type 3 Homo sapiens 50 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 44295672 104009070 CHEMBL50535 ZINC13443592 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50208269 Fc1ccc(CC2CCN(CCCNC(=O)Nc3cccc(c3)C#N)CC2)cc1 InChI=1S/C23H27FN4O/c24-21-7-5-18(6-8-21)15-19-9-13-28(14-10-19)12-2-11-26-23(29)27-22-4-1-3-20(16-22)17-25/h1,3-8,16,19H,2,9-15H2,(H2,26,27,29) JHJVGMKZQAABON-UHFFFAOYSA-N 50115021 1-(3-Cyano-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43677 C-C chemokine receptor type 3 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115021&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 22393430 104009009 CHEMBL43677 ZINC13443482 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50584999 CC[C@H](O)[C@H]1C[C@@H](Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(c1)C(C)=O InChI=1S/C27H37N3O3/c1-3-26(32)25-18-22(17-21-9-5-4-6-10-21)13-16-30(25)15-8-14-28-27(33)29-24-12-7-11-23(19-24)20(2)31/h4-7,9-12,19,22,25-26,32H,3,8,13-18H2,1-2H3,(H2,28,29,33)/t22-,25-,26+/m1/s1 UEKNCACYTQCRSI-RCXJIHSJSA-N 50115012 1-(3-Acetyl-phenyl)-3-{3-[(2R,4S)-4-benzyl-2-((S)-1-hydroxy-propyl)-piperidin-1-yl]-propyl}-urea::CHEMBL50593 C-C chemokine receptor type 3 Homo sapiens 8.00 ChEMBL 10.1016/s0960-894x(02)00206-8 10.7270/Q28W3CN8 12067561 Wacker, DA; Santella, JB; Gardner, DS; Varnes, JG; Estrella, M; DeLucca, GV; Ko, SS; Tanabe, K; Watson, PS; Welch, PK; Covington, M; Stowell, NC; Wadman, EA; Davies, P; Solomon, KA; Newton, RC; Trainor, GL; Friedman, SM; Decicco, CP; Duncia, JV Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115012&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 9868459 104009000 CHEMBL50593 3492 ZINC13443656 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704476 CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C26H32ClN5O3/c1-16-12-18(4-5-21(16)27)15-31-10-8-20(9-11-31)32-22(6-7-24(32)33)26(35)30-23-14-19(25(34)28-3)13-17(2)29-23/h4-5,12-14,20,22H,6-11,15H2,1-3H3,(H,28,34)(H,29,30,35)/t22-/m1/s1 DRTNQHBPTOBJJH-JOCHJYFZSA-N 123068 US10213421, Example 1::US11612596, Example 1.::US8742115, 7 C-C chemokine receptor type 3 Homo sapiens 10.4 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123068&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965995 225149489 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704477 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C27H34ClN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1 DWKNOLCXIFYNFV-HSZRJFAPSA-N 123072 US10213421, Example 2::US11612596, Example 2.::US8742115, 11 C-C chemokine receptor type 3 Homo sapiens 3.20 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123072&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59534386 225149493 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704478 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC1CC1 InChI=1S/C29H36ClN5O3/c1-18-13-21(5-6-24(18)30)17-34-11-9-23(10-12-34)35-25(7-8-27(35)36)29(38)33-26-15-22(14-19(2)32-26)28(37)31-16-20-3-4-20/h5-6,13-15,20,23,25H,3-4,7-12,16-17H2,1-2H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 OUGOQNYEXLDDNI-RUZDIDTESA-N 123076 US10213421, Example 3::US11612596, Example 3.::US8742115, 15 C-C chemokine receptor type 3 Homo sapiens 3.50 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123076&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966926 225149497 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704479 CC(C)CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)16-31-28(37)22-14-20(4)32-26(15-22)33-29(38)25-7-8-27(36)35(25)23-9-11-34(12-10-23)17-21-5-6-24(30)19(3)13-21/h5-6,13-15,18,23,25H,7-12,16-17H2,1-4H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 FNTAOKQFFGXTKD-RUZDIDTESA-N 123078 US10213421, Example 4::US11612596, Example 4.::US8742115, 17 C-C chemokine receptor type 3 Homo sapiens 4.30 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123078&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115103 225149499 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704480 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC(F)F InChI=1S/C27H32ClF2N5O3/c1-16-11-18(3-4-21(16)28)15-34-9-7-20(8-10-34)35-22(5-6-25(35)36)27(38)33-24-13-19(12-17(2)32-24)26(37)31-14-23(29)30/h3-4,11-13,20,22-23H,5-10,14-15H2,1-2H3,(H,31,37)(H,32,33,38)/t22-/m1/s1 GSSCURHTCHTCBR-JOCHJYFZSA-N 123079 US10213421, Example 5::US11612596, Example 5.::US8742115, 18 C-C chemokine receptor type 3 Homo sapiens 4.60 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123079&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966996 225149500 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704481 CCC(C)NC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-5-19(3)32-28(37)22-15-20(4)31-26(16-22)33-29(38)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)18(2)14-21/h6-7,14-16,19,23,25H,5,8-13,17H2,1-4H3,(H,32,37)(H,31,33,38)/t19?,25-/m1/s1 YCXJKGVLGXQFPR-OPEAARRCSA-N 123080 US10213421, Example 6::US11612596, Example 6.::US8742115, 19 C-C chemokine receptor type 3 Homo sapiens 4.00 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123080&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115149 225149501 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704482 CCC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C30H40ClN5O3/c1-6-21(4)34(5)30(39)23-16-20(3)32-27(17-23)33-29(38)26-9-10-28(37)36(26)24-11-13-35(14-12-24)18-22-7-8-25(31)19(2)15-22/h7-8,15-17,21,24,26H,6,9-14,18H2,1-5H3,(H,32,33,38)/t21?,26-/m1/s1 XQJLPJZZKJPBNB-ZTDHTWSHSA-N 123081 US10213421, Example 7::US11612596, Example 7.::US8742115, 21 C-C chemokine receptor type 3 Homo sapiens 5.20 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790202 225149502 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704483 CC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)33(5)29(38)22-15-20(4)31-26(16-22)32-28(37)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)19(3)14-21/h6-7,14-16,18,23,25H,8-13,17H2,1-5H3,(H,31,32,37)/t25-/m1/s1 DYNUOWFKWPVKKC-RUZDIDTESA-N 123082 US10213421, Example 8::US11612596, Example 8.::US8742115, 22 C-C chemokine receptor type 3 Homo sapiens 2.30 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67114949 225149503 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704484 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NC1CCC1 InChI=1S/C29H36ClN5O3/c1-18-14-20(6-7-24(18)30)17-34-12-10-23(11-13-34)35-25(8-9-27(35)36)29(38)33-26-16-21(15-19(2)31-26)28(37)32-22-4-3-5-22/h6-7,14-16,22-23,25H,3-5,8-13,17H2,1-2H3,(H,32,37)(H,31,33,38)/t25-/m1/s1 VLDHAXJQQANHCX-RUZDIDTESA-N 123083 US10213421, Example 9::US11612596, Example 9.::US8742115, 23 C-C chemokine receptor type 3 Homo sapiens 4.20 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123083&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68029259 225149504 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 704485 CCN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C28H36ClN5O3/c1-5-32(4)28(37)21-15-19(3)30-25(16-21)31-27(36)24-8-9-26(35)34(24)22-10-12-33(13-11-22)17-20-6-7-23(29)18(2)14-20/h6-7,14-16,22,24H,5,8-13,17H2,1-4H3,(H,30,31,36)/t24-/m1/s1 KSQBKUICOIKPNV-XMMPIXPASA-N 123096 US10213421, Example 10::US11612596, Example 10.::US8742115, 36 C-C chemokine receptor type 3 Homo sapiens 1.70 US Patent 10.7270/Q2BZ68BF aid1797633 US10213421 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123096&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967066 225149517 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50803888 CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@@]1(C)CCOC1 InChI=1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,18+/m1/s1 DNXKACKCTLURQN-ACJLOTCBSA-N 50255479 CHEMBL4067429 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b01854 10.7270/Q2959M1F 29406702 Lu, H; Yang, T; Xu, Z; Lin, X; Ding, Q; Zhang, Y; Cai, X; Dong, K; Gong, S; Zhang, W; Patel, M; Copley, RCB; Xiang, J; Guan, X; Wren, P; Ren, F GSK Pharmaceuticals R & D http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 100951623 402360319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 50803893 CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@@]1(C)CCOC1 InChI=1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,18+/m1/s1 DNXKACKCTLURQN-ACJLOTCBSA-N 50255479 CHEMBL4067429 C-C chemokine receptor type 3 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b01854 10.7270/Q2959M1F 29406702 Lu, H; Yang, T; Xu, Z; Lin, X; Ding, Q; Zhang, Y; Cai, X; Dong, K; Gong, S; Zhang, W; Patel, M; Copley, RCB; Xiang, J; Guan, X; Wren, P; Ren, F GSK Pharmaceuticals R & D http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255479&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 100951623 402360319 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 51385883 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN(C#N)[C@@H](C[C@H]12)c1[nH]c2ccccc2c1CCn1cc(nn1)-c1cccc(Cl)c1 50559936 CHEMBL4744046 C-C chemokine receptor type 3 Homo sapiens 8300 ChEMBL 10.1016/j.bmc.2020.115546 10.7270/Q2F193D1 32616180 Paciaroni, NG; Norwood, VM; Ratnayake, R; Luesch, H; Huigens, RW University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50559936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50559936&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 132072454 461830328 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267181 CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C26H32ClN5O3/c1-16-12-18(4-5-21(16)27)15-31-10-8-20(9-11-31)32-22(6-7-24(32)33)26(35)30-23-14-19(25(34)28-3)13-17(2)29-23/h4-5,12-14,20,22H,6-11,15H2,1-3H3,(H,28,34)(H,29,30,35)/t22-/m1/s1 DRTNQHBPTOBJJH-JOCHJYFZSA-N 123068 US10213421, Example 1::US11612596, Example 1.::US8742115, 7 C-C chemokine receptor type 3 Homo sapiens 10.4 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123068&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56965995 225149489 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267182 CN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C27H34ClN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1 DWKNOLCXIFYNFV-HSZRJFAPSA-N 123072 US10213421, Example 2::US11612596, Example 2.::US8742115, 11 C-C chemokine receptor type 3 Homo sapiens 3.20 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123072&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 59534386 225149493 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267183 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC1CC1 InChI=1S/C29H36ClN5O3/c1-18-13-21(5-6-24(18)30)17-34-11-9-23(10-12-34)35-25(7-8-27(35)36)29(38)33-26-15-22(14-19(2)32-26)28(37)31-16-20-3-4-20/h5-6,13-15,20,23,25H,3-4,7-12,16-17H2,1-2H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 OUGOQNYEXLDDNI-RUZDIDTESA-N 123076 US10213421, Example 3::US11612596, Example 3.::US8742115, 15 C-C chemokine receptor type 3 Homo sapiens 3.50 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123076&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966926 225149497 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267184 CC(C)CNC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)16-31-28(37)22-14-20(4)32-26(15-22)33-29(38)25-7-8-27(36)35(25)23-9-11-34(12-10-23)17-21-5-6-24(30)19(3)13-21/h5-6,13-15,18,23,25H,7-12,16-17H2,1-4H3,(H,31,37)(H,32,33,38)/t25-/m1/s1 FNTAOKQFFGXTKD-RUZDIDTESA-N 123078 US10213421, Example 4::US11612596, Example 4.::US8742115, 17 C-C chemokine receptor type 3 Homo sapiens 4.30 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123078&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115103 225149499 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267185 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NCC(F)F InChI=1S/C27H32ClF2N5O3/c1-16-11-18(3-4-21(16)28)15-34-9-7-20(8-10-34)35-22(5-6-25(35)36)27(38)33-24-13-19(12-17(2)32-24)26(37)31-14-23(29)30/h3-4,11-13,20,22-23H,5-10,14-15H2,1-2H3,(H,31,37)(H,32,33,38)/t22-/m1/s1 GSSCURHTCHTCBR-JOCHJYFZSA-N 123079 US10213421, Example 5::US11612596, Example 5.::US8742115, 18 C-C chemokine receptor type 3 Homo sapiens 4.60 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123079&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56966996 225149500 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267186 CCC(C)NC(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-5-19(3)32-28(37)22-15-20(4)31-26(16-22)33-29(38)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)18(2)14-21/h6-7,14-16,19,23,25H,5,8-13,17H2,1-4H3,(H,32,37)(H,31,33,38)/t19?,25-/m1/s1 YCXJKGVLGXQFPR-OPEAARRCSA-N 123080 US10213421, Example 6::US11612596, Example 6.::US8742115, 19 C-C chemokine receptor type 3 Homo sapiens 4.00 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123080&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67115149 225149501 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267187 CCC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C30H40ClN5O3/c1-6-21(4)34(5)30(39)23-16-20(3)32-27(17-23)33-29(38)26-9-10-28(37)36(26)24-11-13-35(14-12-24)18-22-7-8-25(31)19(2)15-22/h7-8,15-17,21,24,26H,6,9-14,18H2,1-5H3,(H,32,33,38)/t21?,26-/m1/s1 XQJLPJZZKJPBNB-ZTDHTWSHSA-N 123081 US10213421, Example 7::US11612596, Example 7.::US8742115, 21 C-C chemokine receptor type 3 Homo sapiens 5.20 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123081&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 70790202 225149502 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267188 CC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C29H38ClN5O3/c1-18(2)33(5)29(38)22-15-20(4)31-26(16-22)32-28(37)25-8-9-27(36)35(25)23-10-12-34(13-11-23)17-21-6-7-24(30)19(3)14-21/h6-7,14-16,18,23,25H,8-13,17H2,1-5H3,(H,31,32,37)/t25-/m1/s1 DYNUOWFKWPVKKC-RUZDIDTESA-N 123082 US10213421, Example 8::US11612596, Example 8.::US8742115, 22 C-C chemokine receptor type 3 Homo sapiens 2.30 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123082&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 67114949 225149503 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267189 Cc1cc(cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1)C(=O)NC1CCC1 InChI=1S/C29H36ClN5O3/c1-18-14-20(6-7-24(18)30)17-34-12-10-23(11-13-34)35-25(8-9-27(35)36)29(38)33-26-16-21(15-19(2)31-26)28(37)32-22-4-3-5-22/h6-7,14-16,22-23,25H,3-5,8-13,17H2,1-2H3,(H,32,37)(H,31,33,38)/t25-/m1/s1 VLDHAXJQQANHCX-RUZDIDTESA-N 123083 US10213421, Example 9::US11612596, Example 9.::US8742115, 23 C-C chemokine receptor type 3 Homo sapiens 4.20 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123083&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 68029259 225149504 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8 1267190 CCN(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 InChI=1S/C28H36ClN5O3/c1-5-32(4)28(37)21-15-19(3)30-25(16-21)31-27(36)24-8-9-26(35)34(24)22-10-12-33(13-11-22)17-20-6-7-23(29)18(2)14-20/h6-7,14-16,22,24H,5,8-13,17H2,1-4H3,(H,30,31,36)/t24-/m1/s1 KSQBKUICOIKPNV-XMMPIXPASA-N 123096 US10213421, Example 10::US11612596, Example 10.::US8742115, 36 C-C chemokine receptor type 3 Homo sapiens 1.70 US Patent 10.7270/Q2D50RVC US11612596 Fetscher, A; Scher, JM Alkahest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6236&target=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123096&enzyme=C-C+chemokine+receptor+type+3&column=ki&startPg=0&Increment=50&submit=Search 56967066 225149517 1 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF C-C chemokine receptor type 3 CCR3_HUMAN P51677 B3KVQ1 F5GWL6 Q15748 Q2YDB9 Q86WD2 Q8TDP6 Q9ULY8