BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 246257 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1 InChI=1S/C23H19NO3/c1-27-20-10-11-21-19(13-20)14-22(17-7-3-2-4-8-17)24(21)15-16-6-5-9-18(12-16)23(25)26/h2-14H,15H2,1H3,(H,25,26) ZSWPWUSMEWCUCL-UHFFFAOYSA-N 119453 US8680120, 9-1 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 21 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119453&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907649 220230266 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246258 Cc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1 InChI=1S/C23H19NO2/c1-16-10-11-21-20(12-16)14-22(18-7-3-2-4-8-18)24(21)15-17-6-5-9-19(13-17)23(25)26/h2-14H,15H2,1H3,(H,25,26) IUQINGUKJYNDBR-UHFFFAOYSA-N 119454 US8680120, 9-13 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 89 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119454&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670901 220230267 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246259 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)C(C)C InChI=1S/C20H21NO3/c1-13(2)19-11-16-10-17(24-3)7-8-18(16)21(19)12-14-5-4-6-15(9-14)20(22)23/h4-11,13H,12H2,1-3H3,(H,22,23) FKLJEPXIZZTAMS-UHFFFAOYSA-N 119455 US8680120, 9-15 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 22 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119455&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69671115 220230268 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246260 COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1ccccc1 InChI=1S/C22H18N2O3/c1-27-18-10-11-20-16(12-18)13-21(15-6-3-2-4-7-15)24(20)14-17-8-5-9-19(23-17)22(25)26/h2-13H,14H2,1H3,(H,25,26) MNXIPDOVKILDRF-UHFFFAOYSA-N 119456 US8680120, 9-21 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 13 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119456&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907648 220230269 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246261 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccsc1 InChI=1S/C21H17NO3S/c1-25-18-5-6-19-17(10-18)11-20(16-7-8-26-13-16)22(19)12-14-3-2-4-15(9-14)21(23)24/h2-11,13H,12H2,1H3,(H,23,24) ZYUCYEGMBITLJA-UHFFFAOYSA-N 119457 US8680120, 9-25 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 35 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119457&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670950 220230270 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246262 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccoc1 InChI=1S/C21H17NO4/c1-25-18-5-6-19-17(10-18)11-20(16-7-8-26-13-16)22(19)12-14-3-2-4-15(9-14)21(23)24/h2-11,13H,12H2,1H3,(H,23,24) JCCLVIMVFWCORQ-UHFFFAOYSA-N 119458 US8680120, 9-32 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 11 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119458&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907865 220230271 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246263 COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1ccsc1 InChI=1S/C20H16N2O3S/c1-25-16-5-6-18-14(9-16)10-19(13-7-8-26-12-13)22(18)11-15-3-2-4-17(21-15)20(23)24/h2-10,12H,11H2,1H3,(H,23,24) HZELXPSZKJJBLK-UHFFFAOYSA-N 119459 US8680120, 9-35 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 23 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119459&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907864 220230272 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246264 COc1cc2cc(-c3ccccc3)n(Cc3cccc(c3)C(O)=O)c2cc1F InChI=1S/C23H18FNO3/c1-28-22-12-18-11-20(16-7-3-2-4-8-16)25(21(18)13-19(22)24)14-15-6-5-9-17(10-15)23(26)27/h2-13H,14H2,1H3,(H,26,27) KOCMVEOJQIRNMR-UHFFFAOYSA-N 119460 US8680120, 9-43 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 13 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119460&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670884 220230273 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246265 COc1ccc2n(Cc3cccc(C(O)=O)c3F)c(cc2c1)-c1ccccc1 InChI=1S/C23H18FNO3/c1-28-18-10-11-20-17(12-18)13-21(15-6-3-2-4-7-15)25(20)14-16-8-5-9-19(22(16)24)23(26)27/h2-13H,14H2,1H3,(H,26,27) ONHMWDRBNCMSPT-UHFFFAOYSA-N 119461 US8680120, 9-44 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 19 US Patent 10.7270/Q2183554 aid1800388 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119461&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670904 220230274 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246266 COc1cc2cc(-c3ccccc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl InChI=1S/C22H17ClN2O3/c1-28-21-11-15-10-19(14-6-3-2-4-7-14)25(20(15)12-17(21)23)13-16-8-5-9-18(24-16)22(26)27/h2-12H,13H2,1H3,(H,26,27) XSACHPODNGCEMY-UHFFFAOYSA-N 119462 US8680120, 25-9 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 67 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119462&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69671038 220230275 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246267 COc1ccc2n(Cc3ccc(o3)C(O)=O)c(cc2c1)-c1cccc(F)c1 InChI=1S/C21H16FNO4/c1-26-16-5-7-18-14(10-16)11-19(13-3-2-4-15(22)9-13)23(18)12-17-6-8-20(27-17)21(24)25/h2-11H,12H2,1H3,(H,24,25) QKUJAACEYCIDRJ-UHFFFAOYSA-N 119463 US8680120, 25-11 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 34 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119463&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907866 220230276 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246268 COc1ccc2n(Cc3csc(n3)C(O)=O)c(cc2c1)-c1ccccc1 InChI=1S/C20H16N2O3S/c1-25-16-7-8-17-14(9-16)10-18(13-5-3-2-4-6-13)22(17)11-15-12-26-19(21-15)20(23)24/h2-10,12H,11H2,1H3,(H,23,24) UGVGPIXOUUXAAC-UHFFFAOYSA-N 119464 US8680120, 25-12 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 55 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119464&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907867 220230277 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246269 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccnc1 InChI=1S/C22H18N2O3/c1-27-19-7-8-20-18(11-19)12-21(17-6-3-9-23-13-17)24(20)14-15-4-2-5-16(10-15)22(25)26/h2-13H,14H2,1H3,(H,25,26) PMJOTJQSINNTQG-UHFFFAOYSA-N 119465 US8680120, 25-13 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 38 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119465&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69671242 220230278 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246270 COc1cc2cc(-c3ccccc3)n(Cc3cccc(n3)C(O)=O)c2cc1C InChI=1S/C23H20N2O3/c1-15-11-20-17(13-22(15)28-2)12-21(16-7-4-3-5-8-16)25(20)14-18-9-6-10-19(24-18)23(26)27/h3-13H,14H2,1-2H3,(H,26,27) HAFKGXRVBBECLT-UHFFFAOYSA-N 119466 US8680120, 25-16 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 39 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119466&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670955 220230279 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246271 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1F InChI=1S/C23H18FNO3/c1-28-18-9-10-21-17(12-18)13-22(19-7-2-3-8-20(19)24)25(21)14-15-5-4-6-16(11-15)23(26)27/h2-13H,14H2,1H3,(H,26,27) LOSCONKFBKENAT-UHFFFAOYSA-N 119467 US8680120, 25-17 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 32 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119467&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670810 220230280 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246272 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccc(F)c1 InChI=1S/C23H18FNO3/c1-28-20-8-9-21-18(12-20)13-22(16-5-3-7-19(24)11-16)25(21)14-15-4-2-6-17(10-15)23(26)27/h2-13H,14H2,1H3,(H,26,27) DONQECWETAUZLS-UHFFFAOYSA-N 119468 US8680120, 25-18 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 17 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119468&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69671009 220230281 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246273 COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccc(F)cc1 InChI=1S/C23H18FNO3/c1-28-20-9-10-21-18(12-20)13-22(16-5-7-19(24)8-6-16)25(21)14-15-3-2-4-17(11-15)23(26)27/h2-13H,14H2,1H3,(H,26,27) IJCHDZIPTNKYIN-UHFFFAOYSA-N 119469 US8680120, 25-19 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 36 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119469&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670882 220230282 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246274 COc1cc2cc(-c3cccc(F)c3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl InChI=1S/C22H16ClFN2O3/c1-29-21-10-14-9-19(13-4-2-5-15(24)8-13)26(20(14)11-17(21)23)12-16-6-3-7-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28) LWMJSEXGBQWYNA-UHFFFAOYSA-N 119470 US8680120, 25-23 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 32 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119470&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670851 220230283 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246275 COc1cc2cc(-c3ccccc3)n(Cc3ccc(o3)C(O)=O)c2cc1Cl InChI=1S/C21H16ClNO4/c1-26-20-10-14-9-17(13-5-3-2-4-6-13)23(18(14)11-16(20)22)12-15-7-8-19(27-15)21(24)25/h2-11H,12H2,1H3,(H,24,25) JPYCXEJTCVMAPG-UHFFFAOYSA-N 119471 US8680120, 25-26 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 17 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119471&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670809 220230284 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246276 COc1cc2cc(-c3ccccc3F)n(Cc3cccc(n3)C(O)=O)c2cc1F InChI=1S/C22H16F2N2O3/c1-29-21-10-13-9-20(15-6-2-3-7-16(15)23)26(19(13)11-17(21)24)12-14-5-4-8-18(25-14)22(27)28/h2-11H,12H2,1H3,(H,27,28) OXYUWLNOROEKTI-UHFFFAOYSA-N 119472 US8680120, 25-28 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 28 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119472&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50908088 220230285 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246277 COc1cc2cc(-c3cccc(F)c3)n(Cc3cccc(n3)C(O)=O)c2cc1F InChI=1S/C22H16F2N2O3/c1-29-21-10-14-9-19(13-4-2-5-15(23)8-13)26(20(14)11-17(21)24)12-16-6-3-7-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28) WOTFSADZXCFLFZ-UHFFFAOYSA-N 119473 US8680120, 25-29 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 26 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119473&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670796 220230286 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246278 COc1cc2cc(-c3ccc(F)cc3)n(Cc3cccc(n3)C(O)=O)c2cc1F InChI=1S/C22H16F2N2O3/c1-29-21-10-14-9-19(13-5-7-15(23)8-6-13)26(20(14)11-17(21)24)12-16-3-2-4-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28) YXPWKAMVDKTKQV-UHFFFAOYSA-N 119474 US8680120, 25-31 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 33 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119474&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670895 220230287 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246279 COc1cc2cc(-c3cccnc3)n(Cc3cccc(n3)C(O)=O)c2cc1F InChI=1S/C21H16FN3O3/c1-28-20-9-14-8-18(13-4-3-7-23-11-13)25(19(14)10-16(20)22)12-15-5-2-6-17(24-15)21(26)27/h2-11H,12H2,1H3,(H,26,27) RZPLBSGRSHMBGQ-UHFFFAOYSA-N 119475 US8680120, 25-33 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 58 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119475&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670812 220230288 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246280 COc1cc2cc(-c3ccsc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl InChI=1S/C20H15ClN2O3S/c1-26-19-8-13-7-17(12-5-6-27-11-12)23(18(13)9-15(19)21)10-14-3-2-4-16(22-14)20(24)25/h2-9,11H,10H2,1H3,(H,24,25) RWYDYTGAATYIBK-UHFFFAOYSA-N 119476 US8680120, 25-34 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 54 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119476&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670943 220230289 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246281 COc1cc2cc(-c3ccccc3)n(Cc3ccc(o3)C(O)=O)c2cc1C InChI=1S/C22H19NO4/c1-14-10-18-16(12-21(14)26-2)11-19(15-6-4-3-5-7-15)23(18)13-17-8-9-20(27-17)22(24)25/h3-12H,13H2,1-2H3,(H,24,25) MWFITRYZSCMXPL-UHFFFAOYSA-N 119477 US8680120, 25-36 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 35 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119477&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670960 220230290 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246282 COc1cc2cc(-c3ccoc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl InChI=1S/C20H15ClN2O4/c1-26-19-8-13-7-17(12-5-6-27-11-12)23(18(13)9-15(19)21)10-14-3-2-4-16(22-14)20(24)25/h2-9,11H,10H2,1H3,(H,24,25) CLYDIMUKBUEGRQ-UHFFFAOYSA-N 119478 US8680120, 25-37 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 27 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119478&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 69670842 220230291 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246283 COc1cc2cc(-c3ccoc3)n(Cc3ccc(o3)C(O)=O)c2cc1Cl InChI=1S/C19H14ClNO5/c1-24-18-7-12-6-15(11-4-5-25-10-11)21(16(12)8-14(18)20)9-13-2-3-17(26-13)19(22)23/h2-8,10H,9H2,1H3,(H,22,23) NPLRLZMOUSTGKG-UHFFFAOYSA-N 119479 US8680120, 25-38 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 22 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119479&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50908090 220230292 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246284 COc1cc2cc(-c3ccsc3)n(Cc3cccc(n3)C(O)=O)c2cc1C InChI=1S/C21H18N2O3S/c1-13-8-18-15(10-20(13)26-2)9-19(14-6-7-27-12-14)23(18)11-16-4-3-5-17(22-16)21(24)25/h3-10,12H,11H2,1-2H3,(H,24,25) CTPVPIPUPQBRGA-UHFFFAOYSA-N 119480 US8680120, 25-39 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 37 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119480&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907868 220230293 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246285 COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1cc(F)ccc1F InChI=1S/C22H16F2N2O3/c1-29-16-6-8-20-13(9-16)10-21(17-11-14(23)5-7-18(17)24)26(20)12-15-3-2-4-19(25-15)22(27)28/h2-11H,12H2,1H3,(H,27,28) JZSRAEAMSHQMLU-UHFFFAOYSA-N 119481 US8680120, 25-41 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 25 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119481&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50908089 220230294 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246286 COc1cc2cc(-c3cccnc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl InChI=1S/C21H16ClN3O3/c1-28-20-9-14-8-18(13-4-3-7-23-11-13)25(19(14)10-16(20)22)12-15-5-2-6-17(24-15)21(26)27/h2-11H,12H2,1H3,(H,26,27) MZBDRQVEULUYPF-UHFFFAOYSA-N 119482 US8680120, 25-42 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 28 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119482&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907869 220230295 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 246287 CCC(C)c1cc2cc(OC)c(Cl)cc2n1Cc1cccc(n1)C(O)=O InChI=1S/C20H21ClN2O3/c1-4-12(2)17-8-13-9-19(26-3)15(21)10-18(13)23(17)11-14-6-5-7-16(22-14)20(24)25/h5-10,12H,4,11H2,1-3H3,(H,24,25) BDCCHFGQWVYVDB-UHFFFAOYSA-N 119483 US8680120, 25-44 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 51 US Patent 10.7270/Q2183554 aid1800389 US8680120 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Kissei Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=119483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=119483&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 50907870 220230296 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50295512 OC(=O)c1cccc(n1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1 InChI=1S/C23H16ClNO3S/c24-16-9-10-21(28-14-15-5-2-1-3-6-15)18(13-16)17-11-12-29-22(17)19-7-4-8-20(25-19)23(26)27/h1-13H,14H2,(H,26,27) CZCMZYYRRYEIHW-UHFFFAOYSA-N 50160913 6-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridine-2-carboxylic acid::CHEMBL362851 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 12 ChEMBL 10.1016/j.bmcl.2004.12.005 10.7270/Q2SF2VNV 15686932 Ducharme, Y; Blouin, M; Carriere, MC; Chateauneuf, A; Cote, B; Denis, D; Frenette, R; Greig, G; Kargman, S; Lamontagne, S; Martins, E; Nantel, F; O'Neill, G; Sawyer, N; Metters, KM; Friesen, RW Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160913&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44392460 104047351 CHEMBL362851 ZINC28335098 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50441362 CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 RVMVCPKCWWFOEL-UHFFFAOYSA-M 50259548 6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-2-carboxylate Sodium::CHEMBL467510::sodium 6-(5'-chloro-2'-isobutoxybiphenyl-2-yl)picolinate Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 12.6 ChEMBL 10.1016/j.bmcl.2008.11.032 10.7270/Q2N879N5 19036582 Hall, A; Brown, SH; Budd, C; Clayton, NM; Giblin, GM; Goldsmith, P; Hayhow, TG; Hurst, DN; Naylor, A; Anthony Rawlings, D; Scoccitti, T; Wilson, AW; Winchester, WJ GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259548&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 58974076 104109818 CHEMBL467510 ZINC34661093 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50553033 Cc1sc(C)c(C(=O)NC2(CC2)c2ccc(cc2)C(O)=O)c1Cc1ccc(cc1)C(F)(F)F InChI=1S/C25H22F3NO3S/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)33-14)22(30)29-24(11-12-24)18-9-5-17(6-10-18)23(31)32/h3-10H,11-13H2,1-2H3,(H,29,30)(H,31,32) QJZQFVRFJCGDKF-UHFFFAOYSA-N 50308131 4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}-carbonyl)amino]cyclopropyl}benzoic Acid::CHEMBL597997 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus >29000 ChEMBL 10.1021/jm901771h 10.7270/Q29W0FMT 20163116 Blouin, M; Han, Y; Burch, J; Farand, J; Mellon, C; Gaudreault, M; Wrona, M; Levesque, JF; Denis, D; Mathieu, MC; Stocco, R; Vigneault, E; Therien, A; Clark, P; Rowland, S; Xu, D; O'Neill, G; Ducharme, Y; Friesen, R Merck Frosst Centre for Therapeutic Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308131&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 24952929 104162492 CHEMBL597997 4041 ZINC43206034 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754599 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1Cl)C(O)=O InChI=1S/C19H14Cl2N4O2/c1-11-6-18(19(26)27)22-24(11)10-14-8-12(20)7-13-9-17(23-25(13)14)15-4-2-3-5-16(15)21/h2-9H,10H2,1H3,(H,26,27) DFRYVJNIRDUHCM-UHFFFAOYSA-N 50240139 CHEMBL4089560 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 220 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240139&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448518 85714547 CHEMBL4089560 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754600 CCCC\C=C\c1cc(Cn2nc(cc2C)C(O)=O)n2nc(cc2c1)-c1ccccc1 InChI=1S/C25H26N4O2/c1-3-4-5-7-10-19-14-21-16-23(20-11-8-6-9-12-20)27-29(21)22(15-19)17-28-18(2)13-24(26-28)25(30)31/h6-16H,3-5,17H2,1-2H3,(H,30,31)/b10-7+ IRCMRZBRVZLJJE-JXMROGBWSA-N 50240140 CHEMBL4097281 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1500 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240140&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448517 85714546 CHEMBL4097281 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754601 Cc1cc(nn1Cc1cc(C=C)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C21H18N4O2/c1-3-15-10-17-12-19(16-7-5-4-6-8-16)23-25(17)18(11-15)13-24-14(2)9-20(22-24)21(26)27/h3-12H,1,13H2,2H3,(H,26,27) NDWZKPNQZXVJDQ-UHFFFAOYSA-N 50240141 CHEMBL4091957 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 360 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240141&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448552 85714589 CHEMBL4091957 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754602 Cc1cc(nn1Cc1cc(cc2cc(nn12)-c1ccccc1)C#N)C(O)=O InChI=1S/C20H15N5O2/c1-13-7-19(20(26)27)22-24(13)12-17-9-14(11-21)8-16-10-18(23-25(16)17)15-5-3-2-4-6-15/h2-10H,12H2,1H3,(H,26,27) RKYQCDRFPQMDDM-UHFFFAOYSA-N 50240142 CHEMBL4071137 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1000 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240142&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448556 85714593 CHEMBL4071137 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754603 Cc1cc(nn1Cc1cc(cc2cc(nn12)-c1ccccc1)C(F)(F)F)C(O)=O InChI=1S/C20H15F3N4O2/c1-12-7-18(19(28)29)24-26(12)11-16-9-14(20(21,22)23)8-15-10-17(25-27(15)16)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,28,29) AWRHCSUWPCXAER-UHFFFAOYSA-N 50240143 CHEMBL4081686 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 300 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240143&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448557 85714594 CHEMBL4081686 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754604 Cc1cc(nn1Cc1cc(C)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C20H18N4O2/c1-13-8-16-11-18(15-6-4-3-5-7-15)22-24(16)17(9-13)12-23-14(2)10-19(21-23)20(25)26/h3-11H,12H2,1-2H3,(H,25,26) OCJUAXMHOFCFIC-UHFFFAOYSA-N 50240144 CHEMBL4095087 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 450 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240144&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 22521086 85714639 CHEMBL4095087 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754605 COc1cc(Cn2nc(cc2C)C(O)=O)n2nc(cc2c1)-c1ccccc1 InChI=1S/C20H18N4O3/c1-13-8-19(20(25)26)21-23(13)12-16-10-17(27-2)9-15-11-18(22-24(15)16)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,25,26) FIGPQBZZCOIMKC-UHFFFAOYSA-N 50240145 CHEMBL4102847 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 9600 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240145&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448591 85714641 CHEMBL4102847 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754606 COc1ccc(Cn2nc(cc2C)C(O)=O)n2nc(cc12)-c1ccccc1 InChI=1S/C20H18N4O3/c1-13-10-17(20(25)26)21-23(13)12-15-8-9-19(27-2)18-11-16(22-24(15)18)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,25,26) PYUBKFYWFKRLAK-UHFFFAOYSA-N 50240146 CHEMBL4078569 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1100 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240146&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448663 85714729 CHEMBL4078569 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754607 Cc1cc(nn1Cc1c(Cl)ccc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C19H15ClN4O2/c1-12-9-17(19(25)26)21-23(12)11-18-15(20)8-7-14-10-16(22-24(14)18)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,25,26) MEAWVTYYMPXMHA-UHFFFAOYSA-N 50240147 CHEMBL4064961 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 540 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240147&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448678 85714770 CHEMBL4064961 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754608 Cc1cc(nn1Cc1ccc(Cl)c2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C19H15ClN4O2/c1-12-9-17(19(25)26)21-23(12)11-14-7-8-15(20)18-10-16(22-24(14)18)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,25,26) ZPUTURLQDGUCTE-UHFFFAOYSA-N 50240148 CHEMBL4073554 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 2600 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240148&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448702 85714813 CHEMBL4073554 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754609 Cc1cc(nn1Cc1cccc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C19H16N4O2/c1-13-10-18(19(24)25)20-22(13)12-16-9-5-8-15-11-17(21-23(15)16)14-6-3-2-4-7-14/h2-11H,12H2,1H3,(H,24,25) YOVWTRMZGCXLRE-UHFFFAOYSA-N 50240149 CHEMBL4094186 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 120 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240149&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448703 85714815 CHEMBL4094186 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754610 CC(C)c1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C21H19ClN4O2/c1-13(2)20-11-19(21(27)28)23-25(20)12-17-9-15(22)8-16-10-18(24-26(16)17)14-6-4-3-5-7-14/h3-11,13H,12H2,1-2H3,(H,27,28) WCUKXMUJNMHJPB-UHFFFAOYSA-N 50240150 CHEMBL4061088 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1200 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240150&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448719 85714856 CHEMBL4061088 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754611 CCCc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C21H19ClN4O2/c1-2-6-16-11-20(21(27)28)23-25(16)13-18-10-15(22)9-17-12-19(24-26(17)18)14-7-4-3-5-8-14/h3-5,7-12H,2,6,13H2,1H3,(H,27,28) UQEKDCOWURSVLN-UHFFFAOYSA-N 50240151 CHEMBL4096952 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 97 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240151&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448720 85714858 CHEMBL4096952 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754612 CCc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C20H17ClN4O2/c1-2-15-10-19(20(26)27)22-24(15)12-17-9-14(21)8-16-11-18(23-25(16)17)13-6-4-3-5-7-13/h3-11H,2,12H2,1H3,(H,26,27) WATJRODZCIKBCB-UHFFFAOYSA-N 50240152 CHEMBL4069759 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 300 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240152&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448297 85714228 CHEMBL4069759 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754613 OC(=O)c1ccn(Cc2cc(Cl)cc3cc(nn23)-c2ccccc2)c1 InChI=1S/C19H14ClN3O2/c20-15-8-16-10-18(13-4-2-1-3-5-13)21-23(16)17(9-15)12-22-7-6-14(11-22)19(24)25/h1-11H,12H2,(H,24,25) QPDZIPBHOGIEFE-UHFFFAOYSA-N 50240154 CHEMBL4088199 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 190 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240154&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448874 85715108 CHEMBL4088199 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754614 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)C(C)(C)C)C(O)=O InChI=1S/C17H19ClN4O2/c1-10-5-14(16(23)24)19-21(10)9-13-7-11(18)6-12-8-15(17(2,3)4)20-22(12)13/h5-8H,9H2,1-4H3,(H,23,24) SBRGYYKOTCDKPC-UHFFFAOYSA-N 50240155 CHEMBL4070667 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 2100 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240155&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448947 85715219 CHEMBL4070667 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754615 CCCCc1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)n2n1 InChI=1S/C17H19ClN4O2/c1-3-4-5-13-9-14-7-12(18)8-15(22(14)19-13)10-21-11(2)6-16(20-21)17(23)24/h6-9H,3-5,10H2,1-2H3,(H,23,24) FXZLSWANEQHAPO-UHFFFAOYSA-N 50240156 CHEMBL4062041 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1900 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240156&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449052 85715405 CHEMBL4062041 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754616 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)C1CC1)C(O)=O InChI=1S/C16H15ClN4O2/c1-9-4-15(16(22)23)18-20(9)8-13-6-11(17)5-12-7-14(10-2-3-10)19-21(12)13/h4-7,10H,2-3,8H2,1H3,(H,22,23) FIUGWCISHIFUBG-UHFFFAOYSA-N 50240157 CHEMBL4083777 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 180 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240157&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449106 85715498 CHEMBL4083777 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754617 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)C1CCCC1)C(O)=O InChI=1S/C18H19ClN4O2/c1-11-6-17(18(24)25)20-22(11)10-15-8-13(19)7-14-9-16(21-23(14)15)12-4-2-3-5-12/h6-9,12H,2-5,10H2,1H3,(H,24,25) LKQLCCQTHLTJMH-UHFFFAOYSA-N 50240158 CHEMBL4089147 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 410 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240158&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449228 85715677 CHEMBL4089147 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754618 COc1ccc(cc1)-c1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)n2n1 InChI=1S/C20H17ClN4O3/c1-12-7-19(20(26)27)22-24(12)11-16-9-14(21)8-15-10-18(23-25(15)16)13-3-5-17(28-2)6-4-13/h3-10H,11H2,1-2H3,(H,26,27) PTPMKLSFNHFVQX-UHFFFAOYSA-N 50240159 CHEMBL4081279 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 410 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240159&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448876 85715111 CHEMBL4081279 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754619 COc1cccc(c1)-c1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)n2n1 InChI=1S/C20H17ClN4O3/c1-12-6-19(20(26)27)22-24(12)11-16-9-14(21)8-15-10-18(23-25(15)16)13-4-3-5-17(7-13)28-2/h3-10H,11H2,1-2H3,(H,26,27) VHHVQHFVZFIJNQ-UHFFFAOYSA-N 50240160 CHEMBL4099299 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 110 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240160&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449004 85715316 CHEMBL4099299 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754620 COc1ccccc1-c1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)n2n1 InChI=1S/C20H17ClN4O3/c1-12-7-18(20(26)27)22-24(12)11-15-9-13(21)8-14-10-17(23-25(14)15)16-5-3-4-6-19(16)28-2/h3-10H,11H2,1-2H3,(H,26,27) YIFVSDJEEIDJLW-UHFFFAOYSA-N 50240161 CHEMBL4088628 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 840 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240161&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449079 85715453 CHEMBL4088628 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754621 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1cccc(Cl)c1)C(O)=O InChI=1S/C19H14Cl2N4O2/c1-11-5-18(19(26)27)22-24(11)10-16-8-14(21)7-15-9-17(23-25(15)16)12-3-2-4-13(20)6-12/h2-9H,10H2,1H3,(H,26,27) MZVVDPHDZVWIQX-UHFFFAOYSA-N 50240162 CHEMBL4061415 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 150 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240162&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448772 85714964 CHEMBL4061415 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754622 CC(C)Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C22H21ClN4O2/c1-14(2)8-17-11-21(22(28)29)24-26(17)13-19-10-16(23)9-18-12-20(25-27(18)19)15-6-4-3-5-7-15/h3-7,9-12,14H,8,13H2,1-2H3,(H,28,29) YTHXJOGTZIQQJR-UHFFFAOYSA-N 50240163 CHEMBL4089248 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 2000 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240163&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449171 85715588 CHEMBL4089248 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754623 OC(=O)c1ccn(Cc2cc(Cl)cc3cc(nn23)-c2ccccc2)n1 InChI=1S/C18H13ClN4O2/c19-13-8-14-10-17(12-4-2-1-3-5-12)21-23(14)15(9-13)11-22-7-6-16(20-22)18(24)25/h1-10H,11H2,(H,24,25) YFIGFCKYLLZSPI-UHFFFAOYSA-N 50240164 CHEMBL4066926 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 89 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240164&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448913 85715168 CHEMBL4066926 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754624 CC(C)Cc1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)n2n1 InChI=1S/C17H19ClN4O2/c1-10(2)4-13-8-14-6-12(18)7-15(22(14)19-13)9-21-11(3)5-16(20-21)17(23)24/h5-8,10H,4,9H2,1-3H3,(H,23,24) ZLWLMTKSJPSWGD-UHFFFAOYSA-N 50240165 CHEMBL4091562 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1400 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240165&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44448976 85715265 CHEMBL4091562 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754625 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)C1CCCCC1)C(O)=O InChI=1S/C19H21ClN4O2/c1-12-7-18(19(25)26)21-23(12)11-16-9-14(20)8-15-10-17(22-24(15)16)13-5-3-2-4-6-13/h7-10,13H,2-6,11H2,1H3,(H,25,26) WXJYXCBOQAHSHU-UHFFFAOYSA-N 50240166 CHEMBL4060959 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 71 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240166&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449136 85715540 CHEMBL4060959 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754626 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C19H14Cl2N4O2/c1-11-6-18(19(26)27)22-24(11)10-16-8-14(21)7-15-9-17(23-25(15)16)12-2-4-13(20)5-3-12/h2-9H,10H2,1H3,(H,26,27) VZALZVDKYCHOHT-UHFFFAOYSA-N 50240167 CHEMBL4067374 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 290 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240167&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449053 85715407 CHEMBL4067374 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754627 Cc1cc(nn1Cc1cc(Cl)cc2cc(oc12)-c1ccccc1)C(O)=O InChI=1S/C20H15ClN2O3/c1-12-7-17(20(24)25)22-23(12)11-15-9-16(21)8-14-10-18(26-19(14)15)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,24,25) GKKBLQYJVQMYST-UHFFFAOYSA-N 50419410 CHEMBL1915252 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 22 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419410&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 57399080 163368434 CHEMBL1915252 ZINC43197591 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754628 CC(=O)c1cc(Cn2nc(cc2C)C(O)=O)n2nc(cc2c1)-c1ccccc1 InChI=1S/C21H18N4O3/c1-13-8-20(21(27)28)22-24(13)12-18-10-16(14(2)26)9-17-11-19(23-25(17)18)15-6-4-3-5-7-15/h3-11H,12H2,1-2H3,(H,27,28) CTJADXDUADVWBQ-UHFFFAOYSA-N 50240168 CHEMBL4099699 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 600 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240168&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449107 85715499 CHEMBL4099699 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754629 COc1ccc2cc(nn2c1Cn1nc(cc1C)C(O)=O)-c1ccccc1 InChI=1S/C20H18N4O3/c1-13-10-17(20(25)26)21-23(13)12-18-19(27-2)9-8-15-11-16(22-24(15)18)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,25,26) UGFWWEDIMCNJAR-UHFFFAOYSA-N 50240169 CHEMBL4067673 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1500 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240169&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 44449202 85715634 CHEMBL4067673 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50754630 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C19H15ClN4O2/c1-12-7-18(19(25)26)21-23(12)11-16-9-14(20)8-15-10-17(22-24(15)16)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,25,26) XEFFAIIXHQWESO-UHFFFAOYSA-N 50240170 CHEMBL4064816 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 9.4 ChEMBL 10.1016/j.bmc.2017.03.003 10.7270/Q29Z9728 28342692 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240170&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 24821056 85716225 CHEMBL4064816 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790085 OC(=O)c1ccc(Sc2cc(Cl)cc3sc(nc23)N2CCC=CC2)o1 InChI=1S/C17H13ClN2O3S2/c18-10-8-12(24-14-5-4-11(23-14)16(21)22)15-13(9-10)25-17(19-15)20-6-2-1-3-7-20/h1-2,4-5,8-9H,3,6-7H2,(H,21,22) VCHHYIKJVLRKEK-UHFFFAOYSA-N 50252452 CHEMBL4074797 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 6.4 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252452&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052565 401957530 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790086 OC(=O)c1ccc(Cc2cc(Cl)cc3sc(nc23)N2CCC=CC2)o1 InChI=1S/C18H15ClN2O3S/c19-12-8-11(9-13-4-5-14(24-13)17(22)23)16-15(10-12)25-18(20-16)21-6-2-1-3-7-21/h1-2,4-5,8,10H,3,6-7,9H2,(H,22,23) WCOTXBFNSQJQSG-UHFFFAOYSA-N 50252453 CHEMBL4066183 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 60 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252453&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137632435 401957531 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790087 OC(=O)c1ccn(Cc2cc(Cl)cc3sc(nc23)N2CCC=CC2)n1 InChI=1S/C17H15ClN4O2S/c18-12-8-11(10-22-7-4-13(20-22)16(23)24)15-14(9-12)25-17(19-15)21-5-2-1-3-6-21/h1-2,4,7-9H,3,5-6,10H2,(H,23,24) GVAQXDCQPSGECJ-UHFFFAOYSA-N 50252454 CHEMBL4079668 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 51 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252454&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137650623 401957532 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790088 OC(=O)c1ccn(Cc2cc(Cl)cc3sc(nc23)N2CCC=CC2)c1 InChI=1S/C18H16ClN3O2S/c19-14-8-13(11-21-7-4-12(10-21)17(23)24)16-15(9-14)25-18(20-16)22-5-2-1-3-6-22/h1-2,4,7-10H,3,5-6,11H2,(H,23,24) SVWCMXFCQVPTAJ-UHFFFAOYSA-N 50252455 CHEMBL4103920 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 240 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252455&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137657628 401957533 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790089 Cc1cc(nn1Cc1cc(cc2sc(nc12)N1CCC=CC1)C(O)=O)C(O)=O InChI=1S/C19H18N4O4S/c1-11-7-14(18(26)27)21-23(11)10-13-8-12(17(24)25)9-15-16(13)20-19(28-15)22-5-3-2-4-6-22/h2-3,7-9H,4-6,10H2,1H3,(H,24,25)(H,26,27) GCQXBDBBBMJKGR-UHFFFAOYSA-N 50252456 CHEMBL4096167 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 7900 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252456&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137655484 401957534 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790090 CC(=O)c1cc(Cn2nc(cc2C)C(O)=O)c2nc(sc2c1)N1CCC=CC1 InChI=1S/C20H20N4O3S/c1-12-8-16(19(26)27)22-24(12)11-15-9-14(13(2)25)10-17-18(15)21-20(28-17)23-6-4-3-5-7-23/h3-4,8-10H,5-7,11H2,1-2H3,(H,26,27) CMHIUCYBMJJJAC-UHFFFAOYSA-N 50252457 CHEMBL4063975 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 200 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252457&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137636914 401957535 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790091 CN(C)c1cc(Cn2nc(cc2C)C(O)=O)c2nc(sc2c1)N1CCC=CC1 InChI=1S/C20H23N5O2S/c1-13-9-16(19(26)27)22-25(13)12-14-10-15(23(2)3)11-17-18(14)21-20(28-17)24-7-5-4-6-8-24/h4-5,9-11H,6-8,12H2,1-3H3,(H,26,27) HVQAYABWJYEDIT-UHFFFAOYSA-N 50252458 CHEMBL4088446 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 210 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252458&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052563 401957536 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790092 Cc1cc(nn1Cc1cc(N)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C18H19N5O2S/c1-11-7-14(17(24)25)21-23(11)10-12-8-13(19)9-15-16(12)20-18(26-15)22-5-3-2-4-6-22/h2-3,7-9H,4-6,10,19H2,1H3,(H,24,25) KAUQHCIEJTVBHY-UHFFFAOYSA-N 50252459 CHEMBL4077663 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 7800 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252459&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137652358 401957537 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790093 Cc1cc(nn1Cc1cc(OC(F)(F)F)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C19H17F3N4O3S/c1-11-7-14(17(27)28)24-26(11)10-12-8-13(29-19(20,21)22)9-15-16(12)23-18(30-15)25-5-3-2-4-6-25/h2-3,7-9H,4-6,10H2,1H3,(H,27,28) JLZQAPLSDXCVPA-UHFFFAOYSA-N 50252460 CHEMBL4069371 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 97 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252460&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052250 401957538 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790177 CC(=C)c1cc(Cn2nc(cc2C)C(O)=O)c2nc(sc2c1)N1CCC=CC1 InChI=1S/C21H22N4O2S/c1-13(2)15-10-16(12-25-14(3)9-17(23-25)20(26)27)19-18(11-15)28-21(22-19)24-7-5-4-6-8-24/h4-5,9-11H,1,6-8,12H2,2-3H3,(H,26,27) XARXVTHUUHTKLE-UHFFFAOYSA-N 50252461 CHEMBL4080094 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 160 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252461&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137650133 401957539 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790178 Cc1cc(nn1Cc1cc(C=C)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C20H20N4O2S/c1-3-14-10-15(12-24-13(2)9-16(22-24)19(25)26)18-17(11-14)27-20(21-18)23-7-5-4-6-8-23/h3-5,9-11H,1,6-8,12H2,2H3,(H,25,26) HCVCFPMUVHCWGX-UHFFFAOYSA-N 50252462 CHEMBL4104333 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 9.9 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252462&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052244 401957540 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790179 Cc1cc(nn1Cc1cc(C)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C19H20N4O2S/c1-12-8-14(11-23-13(2)10-15(21-23)18(24)25)17-16(9-12)26-19(20-17)22-6-4-3-5-7-22/h3-4,8-10H,5-7,11H2,1-2H3,(H,24,25) QFRUKEYNEOZQJN-UHFFFAOYSA-N 50252463 CHEMBL4099055 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 2500 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252463&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137661624 401957541 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790180 Cc1cc(nn1Cc1cc(Br)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C18H17BrN4O2S/c1-11-7-14(17(24)25)21-23(11)10-12-8-13(19)9-15-16(12)20-18(26-15)22-5-3-2-4-6-22/h2-3,7-9H,4-6,10H2,1H3,(H,24,25) OQVRFVVPIWTWSQ-UHFFFAOYSA-N 50252464 CHEMBL4081022 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 22 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252464&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052092 401957542 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790181 Cc1cc(nn1Cc1cccc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C18H18N4O2S/c1-12-10-14(17(23)24)20-22(12)11-13-6-5-7-15-16(13)19-18(25-15)21-8-3-2-4-9-21/h2-3,5-7,10H,4,8-9,11H2,1H3,(H,23,24) ITBHEDIUYBDMQP-UHFFFAOYSA-N 50252465 CHEMBL4088913 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 32 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252465&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052403 401957543 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790182 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC(C)=CC1)C(O)=O InChI=1S/C19H19ClN4O2S/c1-11-3-5-23(6-4-11)19-21-17-13(8-14(20)9-16(17)27-19)10-24-12(2)7-15(22-24)18(25)26/h3,7-9H,4-6,10H2,1-2H3,(H,25,26) CFZDSSYDIBUSFR-UHFFFAOYSA-N 50252466 CHEMBL4063118 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 64 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252466&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052559 401957544 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790183 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC(C)=C(C)C1)C(O)=O InChI=1S/C20H21ClN4O2S/c1-11-4-5-24(9-12(11)2)20-22-18-14(7-15(21)8-17(18)28-20)10-25-13(3)6-16(23-25)19(26)27/h6-8H,4-5,9-10H2,1-3H3,(H,26,27) GRCNTZCXEHSCRZ-UHFFFAOYSA-N 50252471 CHEMBL4090279 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 5200 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252471&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137643527 401957545 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790184 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C18H17ClN4O2S/c1-11-7-14(17(24)25)21-23(11)10-12-8-13(19)9-15-16(12)20-18(26-15)22-5-3-2-4-6-22/h2-3,7-9H,4-6,10H2,1H3,(H,24,25) BHLFQIMEGBJYDV-UHFFFAOYSA-N 50252472 CHEMBL4085914 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1.1 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252472&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 72725270 401957546 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790185 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CC=CC1)C(O)=O InChI=1S/C17H15ClN4O2S/c1-10-6-13(16(23)24)20-22(10)9-11-7-12(18)8-14-15(11)19-17(25-14)21-4-2-3-5-21/h2-3,6-8H,4-5,9H2,1H3,(H,23,24) BMXVGSWLIBSGMK-UHFFFAOYSA-N 50252473 CHEMBL4104745 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 110 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252473&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137656506 401957547 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790186 CN1CCN(CC1)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C18H20ClN5O2S/c1-11-7-14(17(25)26)21-24(11)10-12-8-13(19)9-15-16(12)20-18(27-15)23-5-3-22(2)4-6-23/h7-9H,3-6,10H2,1-2H3,(H,25,26) GLNBMGCXXBBMNB-UHFFFAOYSA-N 50252474 CHEMBL4080521 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 4900 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252474&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137646866 401957548 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790187 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCSCC1)C(O)=O InChI=1S/C17H17ClN4O2S2/c1-10-6-13(16(23)24)20-22(10)9-11-7-12(18)8-14-15(11)19-17(26-14)21-2-4-25-5-3-21/h6-8H,2-5,9H2,1H3,(H,23,24) SANVHAQNNWQZIJ-UHFFFAOYSA-N 50252475 CHEMBL4069825 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 66 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252475&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052408 401957549 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790188 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCOCC1)C(O)=O InChI=1S/C17H17ClN4O3S/c1-10-6-13(16(23)24)20-22(10)9-11-7-12(18)8-14-15(11)19-17(26-14)21-2-4-25-5-3-21/h6-8H,2-5,9H2,1H3,(H,23,24) YNEAXIVBNXCUQS-UHFFFAOYSA-N 50252479 CHEMBL4089322 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 63 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252479&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052405 401957550 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790189 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCCCC1)C(O)=O InChI=1S/C18H19ClN4O2S/c1-11-7-14(17(24)25)21-23(11)10-12-8-13(19)9-15-16(12)20-18(26-15)22-5-3-2-4-6-22/h7-9H,2-6,10H2,1H3,(H,24,25) UNJPULAMSOGVTR-UHFFFAOYSA-N 50252480 CHEMBL4097108 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 43 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252480&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052404 401957551 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790190 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCCC1)C(O)=O InChI=1S/C17H17ClN4O2S/c1-10-6-13(16(23)24)20-22(10)9-11-7-12(18)8-14-15(11)19-17(25-14)21-4-2-3-5-21/h6-8H,2-5,9H2,1H3,(H,23,24) GYWXFCLYIQUKCF-UHFFFAOYSA-N 50252481 CHEMBL4079088 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 30 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252481&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052406 401957552 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790191 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC1)C(O)=O InChI=1S/C16H15ClN4O2S/c1-9-5-12(15(22)23)19-21(9)8-10-6-11(17)7-13-14(10)18-16(24-13)20-3-2-4-20/h5-7H,2-4,8H2,1H3,(H,22,23) GIBBLRAUSPTSMN-UHFFFAOYSA-N 50252482 CHEMBL4089396 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 320 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252482&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137642337 401957553 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790192 CCN(CC)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C17H19ClN4O2S/c1-4-21(5-2)17-19-15-11(7-12(18)8-14(15)25-17)9-22-10(3)6-13(20-22)16(23)24/h6-8H,4-5,9H2,1-3H3,(H,23,24) JXCJHGVPDXUWCB-UHFFFAOYSA-N 50252483 CHEMBL4081524 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 6.2 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252483&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052093 401957554 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790193 CCN(C)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C16H17ClN4O2S/c1-4-20(3)16-18-14-10(6-11(17)7-13(14)24-16)8-21-9(2)5-12(19-21)15(22)23/h5-7H,4,8H2,1-3H3,(H,22,23) AQPNJRKVJFGJIP-UHFFFAOYSA-N 50252484 CHEMBL4059569 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 13 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252484&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137634687 401957555 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790194 CN(C)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C15H15ClN4O2S/c1-8-4-11(14(21)22)18-20(8)7-9-5-10(16)6-12-13(9)17-15(23-12)19(2)3/h4-6H,7H2,1-3H3,(H,21,22) YQCCGACXCNMLQC-UHFFFAOYSA-N 50252485 CHEMBL4070938 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 100 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252485&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052407 401957556 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790195 CC(=C)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C16H14ClN3O2S/c1-8(2)15-18-14-10(5-11(17)6-13(14)23-15)7-20-9(3)4-12(19-20)16(21)22/h4-6H,1,7H2,2-3H3,(H,21,22) YIPSLOWBBLCNAX-UHFFFAOYSA-N 50252492 CHEMBL4062313 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 33 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252492&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052095 401957557 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790196 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)C1=CCCCC1)C(O)=O InChI=1S/C19H18ClN3O2S/c1-11-7-15(19(24)25)22-23(11)10-13-8-14(20)9-16-17(13)21-18(26-16)12-5-3-2-4-6-12/h5,7-9H,2-4,6,10H2,1H3,(H,24,25) NQGHRZJYPALMIE-UHFFFAOYSA-N 50252493 CHEMBL4090320 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 110 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252493&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137643997 401957558 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790197 Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)-c1ccccc1)C(O)=O InChI=1S/C19H15ClN4O2/c1-12-7-18(19(25)26)21-23(12)11-16-9-14(20)8-15-10-17(22-24(15)16)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,25,26) XEFFAIIXHQWESO-UHFFFAOYSA-N 50240170 CHEMBL4064816 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 9.4 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240170&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 24821056 85716225 CHEMBL4064816 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790198 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)-c1ccccc1)C(O)=O InChI=1S/C19H14ClN3O2S/c1-11-7-15(19(24)25)22-23(11)10-13-8-14(20)9-16-17(13)21-18(26-16)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,24,25) UWEWQZDPYNXLHB-UHFFFAOYSA-N 50252494 CHEMBL4105272 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 31 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252494&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052247 401957559 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790199 Cc1cc(nn1Cc1cc(Cl)cc2oc(nc12)-c1ccccc1)C(O)=O InChI=1S/C19H14ClN3O3/c1-11-7-15(19(24)25)22-23(11)10-13-8-14(20)9-16-17(13)21-18(26-16)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,24,25) NMNVMXAQPZNHBK-UHFFFAOYSA-N 50252495 CHEMBL4081019 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 8698 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252495&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137646417 401957560 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790200 Cc1cc(nn1Cc1cc(Cl)cc2nc(oc12)-c1ccccc1)C(O)=O InChI=1S/C19H14ClN3O3/c1-11-7-16(19(24)25)22-23(11)10-13-8-14(20)9-15-17(13)26-18(21-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,24,25) NFCSPURXUYWIRX-UHFFFAOYSA-N 50252496 CHEMBL4088911 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 750 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252496&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137644912 401957561 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790201 OC(=O)c1ccc(Oc2cc(Cl)cc3sc(nc23)N2CCC=CC2)o1 InChI=1S/C17H13ClN2O4S/c18-10-8-12(24-14-5-4-11(23-14)16(21)22)15-13(9-10)25-17(19-15)20-6-2-1-3-7-20/h1-2,4-5,8-9H,3,6-7H2,(H,21,22) ZSNPDRQXKFDJIF-UHFFFAOYSA-N 50252497 CHEMBL4087549 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 150 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252497&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052564 401957562 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790202 Cc1cc(nn1Cc1cc(cc2sc(nc12)N1CCC=CC1)C#N)C(O)=O InChI=1S/C19H17N5O2S/c1-12-7-15(18(25)26)22-24(12)11-14-8-13(10-20)9-16-17(14)21-19(27-16)23-5-3-2-4-6-23/h2-3,7-9H,4-6,11H2,1H3,(H,25,26) AXSPHWVQZDLQGR-UHFFFAOYSA-N 50252498 CHEMBL4068881 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 230 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252498&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137633834 401957563 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790203 CNc1cc(Cn2nc(cc2C)C(O)=O)c2nc(sc2c1)N1CCC=CC1 InChI=1S/C19H21N5O2S/c1-12-8-15(18(25)26)22-24(12)11-13-9-14(20-2)10-16-17(13)21-19(27-16)23-6-4-3-5-7-23/h3-4,8-10,20H,5-7,11H2,1-2H3,(H,25,26) ONEIOGCIWUJISL-UHFFFAOYSA-N 50252499 CHEMBL4095679 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 8800 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252499&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137652680 401957564 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790204 COc1cc(Cn2nc(cc2C)C(O)=O)c2nc(sc2c1)N1CCC=CC1 InChI=1S/C19H20N4O3S/c1-12-8-15(18(24)25)21-23(12)11-13-9-14(26-2)10-16-17(13)20-19(27-16)22-6-4-3-5-7-22/h3-4,8-10H,5-7,11H2,1-2H3,(H,24,25) RGDLHOMASTXERE-UHFFFAOYSA-N 50252508 CHEMBL4096603 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 37 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252508&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052560 401957565 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790205 Cc1cc(nn1Cc1cc(F)cc2sc(nc12)N1CCC=CC1)C(O)=O InChI=1S/C18H17FN4O2S/c1-11-7-14(17(24)25)21-23(11)10-12-8-13(19)9-15-16(12)20-18(26-15)22-5-3-2-4-6-22/h2-3,7-9H,4-6,10H2,1H3,(H,24,25) HRFUJPYFYAKIDD-UHFFFAOYSA-N 50252509 CHEMBL4060696 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 17 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252509&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052249 401957566 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790206 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCC=C(C)C1)C(O)=O InChI=1S/C19H19ClN4O2S/c1-11-4-3-5-23(9-11)19-21-17-13(7-14(20)8-16(17)27-19)10-24-12(2)6-15(22-24)18(25)26/h4,6-8H,3,5,9-10H2,1-2H3,(H,25,26) UAXANUPFKSSNSO-UHFFFAOYSA-N 50252510 CHEMBL4076413 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 30 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252510&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 73052094 401957567 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790207 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCS(=O)(=O)CC1)C(O)=O InChI=1S/C17H17ClN4O4S2/c1-10-6-13(16(23)24)20-22(10)9-11-7-12(18)8-14-15(11)19-17(27-14)21-2-4-28(25,26)5-3-21/h6-8H,2-5,9H2,1H3,(H,23,24) RTRIJLFEHJCMLB-UHFFFAOYSA-N 50252511 CHEMBL4097022 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 4200 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252511&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137658953 401957568 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790208 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)N1CCCCCC1)C(O)=O InChI=1S/C19H21ClN4O2S/c1-12-8-15(18(25)26)22-24(12)11-13-9-14(20)10-16-17(13)21-19(27-16)23-6-4-2-3-5-7-23/h8-10H,2-7,11H2,1H3,(H,25,26) GGVIPWZFXUAGPT-UHFFFAOYSA-N 50252512 CHEMBL4061154 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 270 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252512&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137634992 401957569 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790209 CCCN(CC)c1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C18H21ClN4O2S/c1-4-6-22(5-2)18-20-16-12(8-13(19)9-15(16)26-18)10-23-11(3)7-14(21-23)17(24)25/h7-9H,4-6,10H2,1-3H3,(H,24,25) VQXPXACZYQCFGL-UHFFFAOYSA-N 50252514 CHEMBL4073810 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 270 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252514&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137641333 401957570 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790210 CNc1nc2c(Cn3nc(cc3C)C(O)=O)cc(Cl)cc2s1 InChI=1S/C14H13ClN4O2S/c1-7-3-10(13(20)21)18-19(7)6-8-4-9(15)5-11-12(8)17-14(16-2)22-11/h3-5H,6H2,1-2H3,(H,16,17)(H,20,21) ANFASGPUMBZALP-UHFFFAOYSA-N 50252515 CHEMBL4101880 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 470 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252515&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137661287 401957571 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790211 Cc1cc(nn1Cc1cc(Cl)cc2sc(nc12)C1CCCCC1)C(O)=O InChI=1S/C19H20ClN3O2S/c1-11-7-15(19(24)25)22-23(11)10-13-8-14(20)9-16-17(13)21-18(26-16)12-5-3-2-4-6-12/h7-9,12H,2-6,10H2,1H3,(H,24,25) VSJILSWKLUEETB-UHFFFAOYSA-N 50252516 CHEMBL4097566 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 430 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252516&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137660170 401957572 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50790292 Cc1cc(nn1Cc1cc(Cl)cc2nc(sc12)-c1ccccc1)C(O)=O InChI=1S/C19H14ClN3O2S/c1-11-7-16(19(24)25)22-23(11)10-13-8-14(20)9-15-17(13)26-18(21-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,24,25) WBKJAHNQOMNMBF-UHFFFAOYSA-N 50252517 CHEMBL4076480 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 7953 ChEMBL 10.1016/j.bmc.2017.04.028 10.7270/Q2JW8HB8 28483455 Umei, K; Nishigaya, Y; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252517&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137650219 401957573 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836035 OC(=O)c1cccc(Cc2c(nn3ccccc23)-c2ccccc2)n1 InChI=1S/C20H15N3O2/c24-20(25)17-10-6-9-15(21-17)13-16-18-11-4-5-12-23(18)22-19(16)14-7-2-1-3-8-14/h1-12H,13H2,(H,24,25) ZYVJHYVQBJMNQG-UHFFFAOYSA-N 50260654 CHEMBL4092517 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 2300 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260654&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704827 404340373 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836036 OC(=O)c1cccc(Cc2c(nn3cc(F)ccc23)-c2ccccc2)n1 InChI=1S/C20H14FN3O2/c21-14-9-10-18-16(11-15-7-4-8-17(22-15)20(25)26)19(23-24(18)12-14)13-5-2-1-3-6-13/h1-10,12H,11H2,(H,25,26) UCAKUQXGKYVQPX-UHFFFAOYSA-N 50260655 CHEMBL4073415 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 380 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260655&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704854 404340374 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836037 OC(=O)c1cccc(Cc2c(nn3cc(Br)ccc23)-c2ccccc2)n1 InChI=1S/C20H14BrN3O2/c21-14-9-10-18-16(11-15-7-4-8-17(22-15)20(25)26)19(23-24(18)12-14)13-5-2-1-3-6-13/h1-10,12H,11H2,(H,25,26) IAYRXXCKZLCSHQ-UHFFFAOYSA-N 50260656 CHEMBL4083796 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 11 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260656&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151285 404340375 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836039 Cc1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C21H17N3O2/c1-14-10-11-19-17(12-16-8-5-9-18(22-16)21(25)26)20(23-24(19)13-14)15-6-3-2-4-7-15/h2-11,13H,12H2,1H3,(H,25,26) MAFSEYQCCGCGCL-UHFFFAOYSA-N 50260657 CHEMBL4062060 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 19 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260657&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151153 404340376 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836042 OC(=O)c1cccc(Cc2c(nn3cc(ccc23)C(F)(F)F)-c2ccccc2)n1 InChI=1S/C21H14F3N3O2/c22-21(23,24)14-9-10-18-16(11-15-7-4-8-17(25-15)20(28)29)19(26-27(18)12-14)13-5-2-1-3-6-13/h1-10,12H,11H2,(H,28,29) YGPITHSBBNGQPD-UHFFFAOYSA-N 50260658 CHEMBL4091580 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 16 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260658&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151152 404340377 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836043 CC(=C)c1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C23H19N3O2/c1-15(2)17-11-12-21-19(13-18-9-6-10-20(24-18)23(27)28)22(25-26(21)14-17)16-7-4-3-5-8-16/h3-12,14H,1,13H2,2H3,(H,27,28) ZRSKQGABHYUEHQ-UHFFFAOYSA-N 50260659 CHEMBL4067608 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 290 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260659&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704838 404340378 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836046 OC(=O)c1cccc(Cc2c(nn3cc(C=C)ccc23)-c2ccccc2)n1 InChI=1S/C22H17N3O2/c1-2-15-11-12-20-18(13-17-9-6-10-19(23-17)22(26)27)21(24-25(20)14-15)16-7-4-3-5-8-16/h2-12,14H,1,13H2,(H,26,27) WSVKVPXJUJFLJC-UHFFFAOYSA-N 50260660 CHEMBL4088835 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 21 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260660&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151150 404340379 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836048 CSc1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C21H17N3O2S/c1-27-16-10-11-19-17(12-15-8-5-9-18(22-15)21(25)26)20(23-24(19)13-16)14-6-3-2-4-7-14/h2-11,13H,12H2,1H3,(H,25,26) CGINOEKNGJTGSQ-UHFFFAOYSA-N 50260683 CHEMBL4080957 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 87 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260683&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151419 404340380 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836049 CS(=O)(=O)c1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C21H17N3O4S/c1-29(27,28)16-10-11-19-17(12-15-8-5-9-18(22-15)21(25)26)20(23-24(19)13-16)14-6-3-2-4-7-14/h2-11,13H,12H2,1H3,(H,25,26) KXMYAIFPEUIKBB-UHFFFAOYSA-N 50260684 CHEMBL4086353 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 5400 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260684&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 137642895 404340381 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836052 OC(=O)c1cccc(Cc2c(nn3cc(ccc23)C#N)-c2ccccc2)n1 InChI=1S/C21H14N4O2/c22-12-14-9-10-19-17(11-16-7-4-8-18(23-16)21(26)27)20(24-25(19)13-14)15-5-2-1-3-6-15/h1-10,13H,11H2,(H,26,27) FYYWXCPCCFSLEV-UHFFFAOYSA-N 50260685 CHEMBL4104259 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 440 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260685&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704841 404340382 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836053 COc1ccn2nc(c(Cc3cccc(n3)C(O)=O)c2c1)-c1ccccc1 InChI=1S/C21H17N3O3/c1-27-16-10-11-24-19(13-16)17(20(23-24)14-6-3-2-4-7-14)12-15-8-5-9-18(22-15)21(25)26/h2-11,13H,12H2,1H3,(H,25,26) WDIYGCMLWLYDPG-UHFFFAOYSA-N 50260688 CHEMBL4096532 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 9100 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260688&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704834 404340383 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836055 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2Cl)n1 InChI=1S/C20H13Cl2N3O2/c21-12-8-9-18-15(10-13-4-3-7-17(23-13)20(26)27)19(24-25(18)11-12)14-5-1-2-6-16(14)22/h1-9,11H,10H2,(H,26,27) RGRJKXLHYAGXDB-UHFFFAOYSA-N 50260689 CHEMBL4075209 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 640 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260689&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123578350 404340384 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836056 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccc(Cl)cc2)n1 InChI=1S/C20H13Cl2N3O2/c21-13-6-4-12(5-7-13)19-16(18-9-8-14(22)11-25(18)24-19)10-15-2-1-3-17(23-15)20(26)27/h1-9,11H,10H2,(H,26,27) ZHJUUXGYOKLYRD-UHFFFAOYSA-N 50260690 CHEMBL4090286 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1100 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260690&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 68184171 404340385 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836057 COc1cccc(c1)-c1nn2cc(Cl)ccc2c1Cc1cccc(n1)C(O)=O InChI=1S/C21H16ClN3O3/c1-28-16-6-2-4-13(10-16)20-17(19-9-8-14(22)12-25(19)24-20)11-15-5-3-7-18(23-15)21(26)27/h2-10,12H,11H2,1H3,(H,26,27) DTSITWRKWORXKM-UHFFFAOYSA-N 50260691 CHEMBL4070541 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 800 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260691&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123512315 404340386 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836058 COc1ccc(cc1)-c1nn2cc(Cl)ccc2c1Cc1cccc(n1)C(O)=O InChI=1S/C21H16ClN3O3/c1-28-16-8-5-13(6-9-16)20-17(19-10-7-14(22)12-25(19)24-20)11-15-3-2-4-18(23-15)21(26)27/h2-10,12H,11H2,1H3,(H,26,27) GAWUTUBTOHFLOQ-UHFFFAOYSA-N 50260692 CHEMBL4087854 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 5400 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260692&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123163794 404340387 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836059 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccsc2)n1 InChI=1S/C18H12ClN3O2S/c19-12-4-5-16-14(8-13-2-1-3-15(20-13)18(23)24)17(21-22(16)9-12)11-6-7-25-10-11/h1-7,9-10H,8H2,(H,23,24) AKWLYOAQGIIADE-UHFFFAOYSA-N 50260693 CHEMBL4078135 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 110 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260693&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123776027 404340388 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836061 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccco2)n1 InChI=1S/C18H12ClN3O3/c19-11-6-7-15-13(9-12-3-1-4-14(20-12)18(23)24)17(21-22(15)10-11)16-5-2-8-25-16/h1-8,10H,9H2,(H,23,24) GRQHEQPBLXRNAO-UHFFFAOYSA-N 50260694 CHEMBL4098000 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1200 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260694&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123896585 404340389 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836063 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccoc2)n1 InChI=1S/C18H12ClN3O3/c19-12-4-5-16-14(8-13-2-1-3-15(20-13)18(23)24)17(21-22(16)9-12)11-6-7-25-10-11/h1-7,9-10H,8H2,(H,23,24) VVPINDCWCIBJTL-UHFFFAOYSA-N 50260695 CHEMBL4091761 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 130 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260695&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123494981 404340390 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836064 CC(C)Cc1nn2cc(Cl)ccc2c1Cc1cccc(n1)C(O)=O InChI=1S/C18H18ClN3O2/c1-11(2)8-16-14(17-7-6-12(19)10-22(17)21-16)9-13-4-3-5-15(20-13)18(23)24/h3-7,10-11H,8-9H2,1-2H3,(H,23,24) VHIJGULBWQCDOS-UHFFFAOYSA-N 50260696 CHEMBL4077168 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 200 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260696&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123463167 404340391 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836065 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)C2CC2)n1 InChI=1S/C17H14ClN3O2/c18-11-6-7-15-13(16(10-4-5-10)20-21(15)9-11)8-12-2-1-3-14(19-12)17(22)23/h1-3,6-7,9-10H,4-5,8H2,(H,22,23) SOODQZWZJKCSFM-UHFFFAOYSA-N 50260697 CHEMBL4076910 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1500 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260697&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123660109 404340392 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836067 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)N2CCCC2)n1 InChI=1S/C18H17ClN4O2/c19-12-6-7-16-14(10-13-4-3-5-15(20-13)18(24)25)17(21-23(16)11-12)22-8-1-2-9-22/h3-7,11H,1-2,8-10H2,(H,24,25) DBFPCHOWWWVVSU-UHFFFAOYSA-N 50260698 CHEMBL4098345 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1800 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260698&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123567605 404340393 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836068 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)N2CCCCC2)n1 InChI=1S/C19H19ClN4O2/c20-13-7-8-17-15(11-14-5-4-6-16(21-14)19(25)26)18(22-24(17)12-13)23-9-2-1-3-10-23/h4-8,12H,1-3,9-11H2,(H,25,26) LBEOBWMKGXKIMY-UHFFFAOYSA-N 50260699 CHEMBL4065274 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 79 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260699&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151421 404340394 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836071 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)N2CCCCCC2)n1 InChI=1S/C20H21ClN4O2/c21-14-8-9-18-16(12-15-6-5-7-17(22-15)20(26)27)19(23-25(18)13-14)24-10-3-1-2-4-11-24/h5-9,13H,1-4,10-12H2,(H,26,27) NEFCROPKPXGIOQ-UHFFFAOYSA-N 50260700 CHEMBL4074958 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1400 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260700&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123939480 404340395 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836072 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)N2CCSCC2)n1 InChI=1S/C18H17ClN4O2S/c19-12-4-5-16-14(10-13-2-1-3-15(20-13)18(24)25)17(21-23(16)11-12)22-6-8-26-9-7-22/h1-5,11H,6-10H2,(H,24,25) CJKLYLUSQSEXRX-UHFFFAOYSA-N 50260701 CHEMBL4075282 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 260 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260701&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123950503 404340396 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836073 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2)c1 InChI=1S/C21H15ClN2O2/c22-17-9-10-19-18(12-14-5-4-8-16(11-14)21(25)26)20(23-24(19)13-17)15-6-2-1-3-7-15/h1-11,13H,12H2,(H,25,26) UWMVRDDUAYAKJI-UHFFFAOYSA-N 50260702 CHEMBL4089536 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 29 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260702&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151013 404340397 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836076 COc1ccc2c(Cc3cncc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C20H16N4O3/c1-27-15-7-8-18-16(9-14-10-21-11-17(22-14)20(25)26)19(23-24(18)12-15)13-5-3-2-4-6-13/h2-8,10-12H,9H2,1H3,(H,25,26) OVLDKUXVQHVONU-UHFFFAOYSA-N 50260703 CHEMBL4068383 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 4500 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260703&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 68184174 404340398 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836078 OC(=O)c1csc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2)n1 InChI=1S/C18H12ClN3O2S/c19-12-6-7-15-13(8-16-20-14(10-25-16)18(23)24)17(21-22(15)9-12)11-4-2-1-3-5-11/h1-7,9-10H,8H2,(H,23,24) FMLSGJDFXFZGPZ-UHFFFAOYSA-N 50260731 CHEMBL4092926 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 110 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260731&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151418 404340399 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836079 COc1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C21H17N3O3/c1-27-16-10-11-19-17(12-15-8-5-9-18(22-15)21(25)26)20(23-24(19)13-16)14-6-3-2-4-7-14/h2-11,13H,12H2,1H3,(H,25,26) NXMSMRHZCGABAE-UHFFFAOYSA-N 50260732 CHEMBL4105205 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 6.0 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260732&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151149 404340400 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836081 CC(=O)c1ccc2c(Cc3cccc(n3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C22H17N3O3/c1-14(26)16-10-11-20-18(12-17-8-5-9-19(23-17)22(27)28)21(24-25(20)13-16)15-6-3-2-4-7-15/h2-11,13H,12H2,1H3,(H,27,28) KCTSIHWEJOGBHJ-UHFFFAOYSA-N 50260733 CHEMBL4078505 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1100 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260733&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704843 404340401 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836083 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2cccc(Cl)c2)n1 InChI=1S/C20H13Cl2N3O2/c21-13-4-1-3-12(9-13)19-16(18-8-7-14(22)11-25(18)24-19)10-15-5-2-6-17(23-15)20(26)27/h1-9,11H,10H2,(H,26,27) JTPIARXBXRSKON-UHFFFAOYSA-N 50260734 CHEMBL4069239 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 480 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260734&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 68184172 404340402 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836084 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2cccs2)n1 InChI=1S/C18H12ClN3O2S/c19-11-6-7-15-13(9-12-3-1-4-14(20-12)18(23)24)17(21-22(15)10-11)16-5-2-8-25-16/h1-8,10H,9H2,(H,23,24) JWQTXWDAUYQZIY-UHFFFAOYSA-N 50260735 CHEMBL4059518 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1100 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260735&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123243963 404340403 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836091 CC(C)(C)c1nn2cc(Cl)ccc2c1Cc1cccc(n1)C(O)=O InChI=1S/C18H18ClN3O2/c1-18(2,3)16-13(15-8-7-11(19)10-22(15)21-16)9-12-5-4-6-14(20-12)17(23)24/h4-8,10H,9H2,1-3H3,(H,23,24) GTRIWBXKXBBKLV-UHFFFAOYSA-N 50260736 CHEMBL4069600 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 48 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260736&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151420 404340404 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836093 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)C2CCCCC2)n1 InChI=1S/C20H20ClN3O2/c21-14-9-10-18-16(11-15-7-4-8-17(22-15)20(25)26)19(23-24(18)12-14)13-5-2-1-3-6-13/h4,7-10,12-13H,1-3,5-6,11H2,(H,25,26) VAHYFEWQXPLZAC-UHFFFAOYSA-N 50260737 CHEMBL4075546 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 1200 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260737&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 123616733 404340405 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836095 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)N2CCOCC2)n1 InChI=1S/C18H17ClN4O3/c19-12-4-5-16-14(10-13-2-1-3-15(20-13)18(24)25)17(21-23(16)11-12)22-6-8-26-9-7-22/h1-5,11H,6-10H2,(H,24,25) QCFWGHNLXRWDPA-UHFFFAOYSA-N 50260738 CHEMBL4075206 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 740 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260738&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704880 404340406 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836098 COc1ccc2c(Cc3ccc(o3)C(O)=O)c(nn2c1)-c1ccccc1 InChI=1S/C20H16N2O4/c1-25-15-7-9-17-16(11-14-8-10-18(26-14)20(23)24)19(21-22(17)12-15)13-5-3-2-4-6-13/h2-10,12H,11H2,1H3,(H,23,24) RATOLSUFBLQHQN-UHFFFAOYSA-N 50260739 CHEMBL4072169 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 60 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260739&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151284 404340407 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836099 OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2)n1 InChI=1S/C20H14ClN3O2/c21-14-9-10-18-16(11-15-7-4-8-17(22-15)20(25)26)19(23-24(18)12-14)13-5-2-1-3-6-13/h1-10,12H,11H2,(H,25,26) KSNBGOSHJIIPSW-UHFFFAOYSA-N 50260740 CHEMBL4100262 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 8.0 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260740&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 60151147 404340408 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537 50836100 OC(=O)c1cccc(Cc2c(nn3cc(ccc23)C2CC2)-c2ccccc2)n1 InChI=1S/C23H19N3O2/c27-23(28)20-8-4-7-18(24-20)13-19-21-12-11-17(15-9-10-15)14-26(21)25-22(19)16-5-2-1-3-6-16/h1-8,11-12,14-15H,9-10,13H2,(H,27,28) GFPYQYCDGAVNDN-UHFFFAOYSA-N 50260741 CHEMBL4070685 Prostaglandin E2 receptor EP1 subtype Rattus norvegicus 190 ChEMBL 10.1016/j.bmcl.2017.07.055 10.7270/Q2PN983F 28784294 Nishigaya, Y; Umei, K; Saito, Y; Watanabe, H; Kondo, T; Kondo, A; Kawamura, N; Tatani, K; Kohno, Y; Tanaka, N; Seto, S Kyorin Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50260741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6098&target=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50260741&enzyme=Prostaglandin+E2+receptor+EP1+subtype&column=ki&startPg=0&Increment=50&submit=Search 86704858 404340409 1 MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL Prostaglandin E2 receptor EP1 subtype PE2R1_RAT P70597 P97537