BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 229948 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C19H19N3O7/c1-10(17(24)22-14(9-23)18(25)26)8-13-6-7-15(28-13)19(27)29-12-4-2-11(3-5-12)16(20)21/h2-8,14,23H,9H2,1H3,(H3,20,21)(H,22,24)(H,25,26)/b10-8+/t14-/m0/s1 NRFIREHTDRUARE-PLWJUESGSA-N 109582 US8609715, A-1 Enteropeptidase Homo sapiens 2.27 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109582&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982902 186526452 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229949 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCC(O)=O InChI=1S/C18H17N3O6/c1-10(17(24)21-9-15(22)23)8-13-6-7-14(26-13)18(25)27-12-4-2-11(3-5-12)16(19)20/h2-8H,9H2,1H3,(H3,19,20)(H,21,24)(H,22,23)/b10-8+ OWPDXZWOFGNFBB-CSKARUKUSA-N 109583 US8609715, A-2 Enteropeptidase Homo sapiens 1.97 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109583&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982904 186526453 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229950 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C16H14N2O5/c1-9(15(19)20)8-12-6-7-13(22-12)16(21)23-11-4-2-10(3-5-11)14(17)18/h2-8H,1H3,(H3,17,18)(H,19,20)/b9-8+ LZENIMADVPMVOA-CMDGGOBGSA-N 109584 US8609715, A-3 Enteropeptidase Homo sapiens 1.15 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109584&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320284 186526454 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229951 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCC(O)=O InChI=1S/C18H19N3O6/c1-10(17(24)21-9-15(22)23)8-13-6-7-14(26-13)18(25)27-12-4-2-11(3-5-12)16(19)20/h2-7,10H,8-9H2,1H3,(H3,19,20)(H,21,24)(H,22,23) NTYXHZQEBOMOFW-UHFFFAOYSA-N 109585 US8609715, A-4 Enteropeptidase Homo sapiens 2.68 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109585&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982907 186526455 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229952 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C19H21N3O7/c1-10(17(24)22-14(9-23)18(25)26)8-13-6-7-15(28-13)19(27)29-12-4-2-11(3-5-12)16(20)21/h2-7,10,14,23H,8-9H2,1H3,(H3,20,21)(H,22,24)(H,25,26)/t10?,14-/m0/s1 ZOPYDNVNOVCPEI-SBNLOKMTSA-N 109586 US8609715, A-5 Enteropeptidase Homo sapiens 1.37 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109586&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320286 186526456 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229953 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C16H16N2O5/c1-9(15(19)20)8-12-6-7-13(22-12)16(21)23-11-4-2-10(3-5-11)14(17)18/h2-7,9H,8H2,1H3,(H3,17,18)(H,19,20) NLQVBTOKJAZOCJ-UHFFFAOYSA-N 109587 US8609715, A-6 Enteropeptidase Homo sapiens 0.62 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109587&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320287 186526457 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229954 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCCO)CC(O)=O InChI=1S/C21H23N3O7/c1-13(20(28)24(9-2-10-25)12-18(26)27)11-16-7-8-17(30-16)21(29)31-15-5-3-14(4-6-15)19(22)23/h3-8,11,25H,2,9-10,12H2,1H3,(H3,22,23)(H,26,27)/b13-11+ IBOMNIULXQUTNH-ACCUITESSA-N 109588 US8609715, A-7 Enteropeptidase Homo sapiens 1.49 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109588&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320285 186526458 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229955 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCCO)CC(O)=O InChI=1S/C21H25N3O7/c1-13(20(28)24(9-2-10-25)12-18(26)27)11-16-7-8-17(30-16)21(29)31-15-5-3-14(4-6-15)19(22)23/h3-8,13,25H,2,9-12H2,1H3,(H3,22,23)(H,26,27) UWJTXKREKAAFAE-UHFFFAOYSA-N 109589 US8609715, A-9 Enteropeptidase Homo sapiens 3.17 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109589&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982912 186526459 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229956 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCO)Cc1ccccc1 InChI=1S/C25H25N3O5/c1-17(24(30)28(13-14-29)16-18-5-3-2-4-6-18)15-21-11-12-22(32-21)25(31)33-20-9-7-19(8-10-20)23(26)27/h2-12,15,29H,13-14,16H2,1H3,(H3,26,27)/b17-15+ VCDUEKMYTXPHEH-BMRADRMJSA-N 109590 US8609715, A-10 Enteropeptidase Homo sapiens 6.73 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109590&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320244 186526460 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229957 C\C(=C/c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCCO)CCC(O)=O InChI=1S/C22H25N3O7/c1-14(21(29)25(10-2-12-26)11-9-19(27)28)13-17-7-8-18(31-17)22(30)32-16-5-3-15(4-6-16)20(23)24/h3-8,13,26H,2,9-12H2,1H3,(H3,23,24)(H,27,28)/b14-13+ YTUXLZZWBQVBTG-BUHFOSPRSA-N 109591 US8609715, A-12 Enteropeptidase Homo sapiens 3.31 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109591&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320242 186526461 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229958 CC(O)[C@H](NC(=O)C(\C)=C\c1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C20H21N3O7/c1-10(18(25)23-16(11(2)24)19(26)27)9-14-7-8-15(29-14)20(28)30-13-5-3-12(4-6-13)17(21)22/h3-9,11,16,24H,1-2H3,(H3,21,22)(H,23,25)(H,26,27)/b10-9+/t11?,16-/m0/s1 IIOSHSXDCZLCQH-VOGYTRHSSA-N 109592 US8609715, A-14 Enteropeptidase Homo sapiens 3.52 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109592&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982916 186526462 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229959 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C21H23N3O8/c1-11(19(27)24-15(20(28)29)7-9-17(25)26)10-14-6-8-16(31-14)21(30)32-13-4-2-12(3-5-13)18(22)23/h2-6,8,11,15H,7,9-10H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t11?,15-/m0/s1 OQIOMHVSRCEPSQ-MHTVFEQDSA-N 109593 US8609715, A-15 Enteropeptidase Homo sapiens 1.63 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109593&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53240814 186526463 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229960 CC(O)[C@H](NC(=O)C(C)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C20H23N3O7/c1-10(18(25)23-16(11(2)24)19(26)27)9-14-7-8-15(29-14)20(28)30-13-5-3-12(4-6-13)17(21)22/h3-8,10-11,16,24H,9H2,1-2H3,(H3,21,22)(H,23,25)(H,26,27)/t10?,11?,16-/m0/s1 MSXNXYZQFJXAKW-PRDDCLIZSA-N 109594 US8609715, A-16 Enteropeptidase Homo sapiens 1.88 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109594&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982919 186526464 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229961 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCCC(O)=O InChI=1S/C19H21N3O6/c1-11(18(25)22-9-8-16(23)24)10-14-6-7-15(27-14)19(26)28-13-4-2-12(3-5-13)17(20)21/h2-7,11H,8-10H2,1H3,(H3,20,21)(H,22,25)(H,23,24) ZBWKMLRIONLIIC-UHFFFAOYSA-N 109595 US8609715, A-17 Enteropeptidase Homo sapiens 2.43 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109595&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982921 186526465 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229962 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m0/s1 SZJWWBVFVRUWES-SBNLOKMTSA-N 109596 US8609715, A-18 Enteropeptidase Homo sapiens 0.61 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109596&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53240815 186526466 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229963 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N1CCC[C@@H]1C(O)=O InChI=1S/C21H23N3O6/c1-12(19(25)24-10-2-3-16(24)20(26)27)11-15-8-9-17(29-15)21(28)30-14-6-4-13(5-7-14)18(22)23/h4-9,12,16H,2-3,10-11H2,1H3,(H3,22,23)(H,26,27)/t12?,16-/m1/s1 SZHLJUMUJCYLMK-PVQCJRHBSA-N 109597 US8609715, A-19 Enteropeptidase Homo sapiens 1.91 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109597&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982924 186526467 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229964 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N1C[C@H](O)C[C@@H]1C(O)=O InChI=1S/C21H23N3O7/c1-11(19(26)24-10-13(25)9-16(24)20(27)28)8-15-6-7-17(30-15)21(29)31-14-4-2-12(3-5-14)18(22)23/h2-7,11,13,16,25H,8-10H2,1H3,(H3,22,23)(H,27,28)/t11?,13-,16-/m1/s1 VBZWDZBEMAXYPI-ZUZSALNQSA-N 109598 US8609715, A-20 Enteropeptidase Homo sapiens 2.54 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109598&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982926 186526468 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229965 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N1C[C@@H](O)C[C@H]1C(O)=O InChI=1S/C21H23N3O7/c1-11(19(26)24-10-13(25)9-16(24)20(27)28)8-15-6-7-17(30-15)21(29)31-14-4-2-12(3-5-14)18(22)23/h2-7,11,13,16,25H,8-10H2,1H3,(H3,22,23)(H,27,28)/t11?,13-,16-/m0/s1 VBZWDZBEMAXYPI-DKGPUHFJSA-N 109599 US8609715, A-21 Enteropeptidase Homo sapiens 4.81 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109599&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982928 186526469 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229966 C[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C20H22N4O7/c1-10(18(26)24-14(19(27)28)9-16(21)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(22)23/h2-7,10,14H,8-9H2,1H3,(H2,21,25)(H3,22,23)(H,24,26)(H,27,28)/t10-,14+/m1/s1 IZTQESQONZUFKI-YGRLFVJLSA-N 109600 US8609715, A-22 Enteropeptidase Homo sapiens 0.95 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109600&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982930 186526470 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229967 C[C@@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C20H22N4O7/c1-10(18(26)24-14(19(27)28)9-16(21)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(22)23/h2-7,10,14H,8-9H2,1H3,(H2,21,25)(H3,22,23)(H,24,26)(H,27,28)/t10-,14-/m0/s1 IZTQESQONZUFKI-HZMBPMFUSA-N 109601 US8609715, A-23 Enteropeptidase Homo sapiens 2.0 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109601&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982932 186526471 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229968 C[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C21H24N4O7/c1-11(19(27)25-15(20(28)29)7-9-17(22)26)10-14-6-8-16(31-14)21(30)32-13-4-2-12(3-5-13)18(23)24/h2-6,8,11,15H,7,9-10H2,1H3,(H2,22,26)(H3,23,24)(H,25,27)(H,28,29)/t11-,15+/m1/s1 OXVOIWYRXPRXGD-ABAIWWIYSA-N 109602 US8609715, A-24 Enteropeptidase Homo sapiens 1.9 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109602&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982934 186526472 C02716 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229969 C[C@@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C21H24N4O7/c1-11(19(27)25-15(20(28)29)7-9-17(22)26)10-14-6-8-16(31-14)21(30)32-13-4-2-12(3-5-13)18(23)24/h2-6,8,11,15H,7,9-10H2,1H3,(H2,22,26)(H3,23,24)(H,25,27)(H,28,29)/t11-,15-/m0/s1 OXVOIWYRXPRXGD-NHYWBVRUSA-N 109603 US8609715, A-25 Enteropeptidase Homo sapiens 2.1 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109603&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982936 186526473 C02716 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229970 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CC(O)=O)CC(O)=O InChI=1S/C20H21N3O8/c1-11(19(28)23(9-16(24)25)10-17(26)27)8-14-6-7-15(30-14)20(29)31-13-4-2-12(3-5-13)18(21)22/h2-7,11H,8-10H2,1H3,(H3,21,22)(H,24,25)(H,26,27) GTJNXXKNXAEKAD-UHFFFAOYSA-N 109604 US8609715, A-26 Enteropeptidase Homo sapiens 0.68 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109604&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242150 186526474 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229971 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C21H23N3O8/c1-11(19(27)24-15(20(28)29)7-9-17(25)26)10-14-6-8-16(31-14)21(30)32-13-4-2-12(3-5-13)18(22)23/h2-6,8,11,15H,7,9-10H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t11?,15-/m1/s1 OQIOMHVSRCEPSQ-JOPIAHFSSA-N 109605 US8609715, A-27 Enteropeptidase Homo sapiens 0.57 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109605&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242073 186526475 C06379 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229972 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m1/s1 SZJWWBVFVRUWES-LNUXAPHWSA-N 109606 US8609715, A-28 Enteropeptidase Homo sapiens 0.42 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109606&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53240917 186526476 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229973 CCC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C17H18N2O5/c1-2-10(16(20)21)9-13-7-8-14(23-13)17(22)24-12-5-3-11(4-6-12)15(18)19/h3-8,10H,2,9H2,1H3,(H3,18,19)(H,20,21) VVLASUBZKSUGQT-UHFFFAOYSA-N 109607 US8609715, A-29 Enteropeptidase Homo sapiens 0.82 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109607&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982941 186526477 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229974 CC[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C22H25N3O8/c1-2-12(20(28)25-16(21(29)30)8-10-18(26)27)11-15-7-9-17(32-15)22(31)33-14-5-3-13(4-6-14)19(23)24/h3-7,9,12,16H,2,8,10-11H2,1H3,(H3,23,24)(H,25,28)(H,26,27)(H,29,30)/t12-,16-/m1/s1 UFCMIORKELZNIA-MLGOLLRUSA-N 109608 US8609715, A-30 Enteropeptidase Homo sapiens 1.03 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109608&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982943 186526478 C06379 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229975 CCC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C21H23N3O8/c1-2-11(19(27)24-15(20(28)29)10-17(25)26)9-14-7-8-16(31-14)21(30)32-13-5-3-12(4-6-13)18(22)23/h3-8,11,15H,2,9-10H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t11?,15-/m1/s1 VZLDWAUEVAUTSW-JOPIAHFSSA-N 109609 US8609715, A-31 Enteropeptidase Homo sapiens 0.50 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109609&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242074 186526479 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229976 NC(=N)c1ccc(OC(=O)c2ccc(CC(O)=O)o2)cc1 InChI=1S/C14H12N2O5/c15-13(16)8-1-3-9(4-2-8)21-14(19)11-6-5-10(20-11)7-12(17)18/h1-6H,7H2,(H3,15,16)(H,17,18) WBQDRVLVSBHTGT-UHFFFAOYSA-N 109610 US8609715, A-32 Enteropeptidase Homo sapiens 0.62 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109610&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982946 186526480 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229977 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C16H15FN2O5/c1-8(15(20)21)6-10-3-5-13(23-10)16(22)24-12-4-2-9(14(18)19)7-11(12)17/h2-5,7-8H,6H2,1H3,(H3,18,19)(H,20,21) DUCJOCFUUOTITC-UHFFFAOYSA-N 109611 US8609715, A-33 Enteropeptidase Homo sapiens 0.65 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109611&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320243 186526481 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229978 CCCC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C18H20N2O5/c1-2-3-12(17(21)22)10-14-8-9-15(24-14)18(23)25-13-6-4-11(5-7-13)16(19)20/h4-9,12H,2-3,10H2,1H3,(H3,19,20)(H,21,22) YXPRFFNVPAGVIO-UHFFFAOYSA-N 109612 US8609715, A-34 Enteropeptidase Homo sapiens 0.98 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109612&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982949 186526482 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229979 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O8/c1-9(18(27)24-13(19(28)29)8-16(25)26)6-11-3-5-15(31-11)20(30)32-14-4-2-10(17(22)23)7-12(14)21/h2-5,7,9,13H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,13-/m1/s1 DNYIAXWWSUGOGI-WCRCJTMVSA-N 109613 US8609715, A-35 Enteropeptidase Homo sapiens 0.25 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109613&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242075 186526483 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229980 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)S(O)(=O)=O InChI=1S/C15H16N2O6S/c1-9(24(19,20)21)8-12-6-7-13(22-12)15(18)23-11-4-2-10(3-5-11)14(16)17/h2-7,9H,8H2,1H3,(H3,16,17)(H,19,20,21) ITZRBSPXELDJCI-UHFFFAOYSA-N 109614 US8609715, A-36 Enteropeptidase Homo sapiens 0.58 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109614&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982952 186526484 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229981 NC(=N)c1ccc(OC(=O)c2ccc(CCC(O)=O)o2)cc1 InChI=1S/C15H14N2O5/c16-14(17)9-1-3-11(4-2-9)22-15(20)12-7-5-10(21-12)6-8-13(18)19/h1-5,7H,6,8H2,(H3,16,17)(H,18,19) HQGRIKHQMFOQEJ-UHFFFAOYSA-N 109615 US8609715, A-37 Enteropeptidase Homo sapiens 0.64 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109615&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320245 186526485 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229982 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)o2)cc1 InChI=1S/C19H19N3O8/c20-17(21)10-1-3-12(4-2-10)30-19(28)14-7-5-11(29-14)6-8-15(23)22-13(18(26)27)9-16(24)25/h1-5,7,13H,6,8-9H2,(H3,20,21)(H,22,23)(H,24,25)(H,26,27)/t13-/m0/s1 OJLOAPPEYJCQFX-ZDUSSCGKSA-N 109616 US8609715, A-38 Enteropeptidase Homo sapiens 0.57 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109616&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242076 186526486 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229983 NC(=N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)o2)cc1 InChI=1S/C18H17N3O8/c19-16(20)9-1-3-10(4-2-9)29-18(27)13-6-5-11(28-13)7-14(22)21-12(17(25)26)8-15(23)24/h1-6,12H,7-8H2,(H3,19,20)(H,21,22)(H,23,24)(H,25,26)/t12-/m0/s1 TVFBIHLGSAPFRF-LBPRGKRZSA-N 109617 US8609715, A-39 Enteropeptidase Homo sapiens 0.67 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109617&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242077 186526487 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229984 C[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C16H16N2O5/c1-9(15(19)20)8-12-6-7-13(22-12)16(21)23-11-4-2-10(3-5-11)14(17)18/h2-7,9H,8H2,1H3,(H3,17,18)(H,19,20)/t9-/m1/s1 NLQVBTOKJAZOCJ-SECBINFHSA-N 109634 US8609715, A-41 Enteropeptidase Homo sapiens 0.50 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109634&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982978 186526504 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229985 C[C@@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C16H16N2O5/c1-9(15(19)20)8-12-6-7-13(22-12)16(21)23-11-4-2-10(3-5-11)14(17)18/h2-7,9H,8H2,1H3,(H3,17,18)(H,19,20)/t9-/m0/s1 NLQVBTOKJAZOCJ-VIFPVBQESA-N 109635 US8609715, A-42 Enteropeptidase Homo sapiens 0.71 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109635&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982980 186526505 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229986 C[C@@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10-,14-/m0/s1 SZJWWBVFVRUWES-HZMBPMFUSA-N 109636 US8609715, A-43 Enteropeptidase Homo sapiens 0.40 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109636&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242085 186526506 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229987 C[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10-,14+/m1/s1 SZJWWBVFVRUWES-YGRLFVJLSA-N 109637 US8609715, A-44 Enteropeptidase Homo sapiens 0.33 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109637&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242086 186526507 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229988 C[C@@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10-,14+/m0/s1 SZJWWBVFVRUWES-IINYFYTJSA-N 109638 US8609715, A-45 Enteropeptidase Homo sapiens 0.46 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109638&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242087 186526508 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229989 C[C@H](Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(30-13)20(29)31-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10-,14-/m1/s1 SZJWWBVFVRUWES-QMTHXVAHSA-N 109639 US8609715, A-46 Enteropeptidase Homo sapiens 0.35 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109639&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242091 186526509 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229990 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCCc1ccccc1 InChI=1S/C24H25N3O4/c1-16(23(28)27-14-13-17-5-3-2-4-6-17)15-20-11-12-21(30-20)24(29)31-19-9-7-18(8-10-19)22(25)26/h2-12,16H,13-15H2,1H3,(H3,25,26)(H,27,28) FCUZICMQZZVVKV-UHFFFAOYSA-N 109640 US8609715, A-47 Enteropeptidase Homo sapiens 1.9 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109640&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320246 186526510 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229991 CC(C)CCNC(=O)C(C)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H27N3O4/c1-13(2)10-11-24-20(25)14(3)12-17-8-9-18(27-17)21(26)28-16-6-4-15(5-7-16)19(22)23/h4-9,13-14H,10-12H2,1-3H3,(H3,22,23)(H,24,25) DERFIIKIOBAIAV-UHFFFAOYSA-N 109641 US8609715, A-48 Enteropeptidase Homo sapiens 1.3 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109641&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982987 186526511 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229992 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCCN(C)C InChI=1S/C20H26N4O4/c1-13(19(25)23-10-11-24(2)3)12-16-8-9-17(27-16)20(26)28-15-6-4-14(5-7-15)18(21)22/h4-9,13H,10-12H2,1-3H3,(H3,21,22)(H,23,25) ZKBYUPYHRZGBNO-UHFFFAOYSA-N 109642 US8609715, A-49 Enteropeptidase Homo sapiens 7.6 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109642&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982989 186526512 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229993 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCCO InChI=1S/C18H21N3O5/c1-11(17(23)21-8-9-22)10-14-6-7-15(25-14)18(24)26-13-4-2-12(3-5-13)16(19)20/h2-7,11,22H,8-10H2,1H3,(H3,19,20)(H,21,23) SJDVUGBPQDFAAN-UHFFFAOYSA-N 109643 US8609715, A-50 Enteropeptidase Homo sapiens 4.4 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109643&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320316 186526513 C04080 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229994 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N1CCCC1 InChI=1S/C20H23N3O4/c1-13(19(24)23-10-2-3-11-23)12-16-8-9-17(26-16)20(25)27-15-6-4-14(5-7-15)18(21)22/h4-9,13H,2-3,10-12H2,1H3,(H3,21,22) RDNPZJNRANZTQK-UHFFFAOYSA-N 109644 US8609715, A-51 Enteropeptidase Homo sapiens 4.9 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109644&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982992 186526514 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229995 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N1CCCC(C1)C(O)=O InChI=1S/C22H25N3O6/c1-13(20(26)25-10-2-3-15(12-25)21(27)28)11-17-8-9-18(30-17)22(29)31-16-6-4-14(5-7-16)19(23)24/h4-9,13,15H,2-3,10-12H2,1H3,(H3,23,24)(H,27,28) YYZHMTSKPMAKTP-UHFFFAOYSA-N 109645 US8609715, A-52 Enteropeptidase Homo sapiens 2.5 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109645&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982994 186526515 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229996 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(O)=O)CC(O)=O)o2)cc1 InChI=1S/C20H21N3O8/c21-19(22)12-1-3-14(4-2-12)31-20(29)15-7-5-13(30-15)6-8-16(24)23(11-18(27)28)10-9-17(25)26/h1-5,7H,6,8-11H2,(H3,21,22)(H,25,26)(H,27,28) ZAHQADWFJNBMHZ-UHFFFAOYSA-N 109646 US8609715, A-54 Enteropeptidase Homo sapiens 0.60 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109646&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242093 186526516 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229997 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)CC(O)=O)o2)cc1 InChI=1S/C20H21N3O6/c1-2-11-23(12-18(25)26)17(24)10-8-14-7-9-16(28-14)20(27)29-15-5-3-13(4-6-15)19(21)22/h2-7,9H,1,8,10-12H2,(H3,21,22)(H,25,26) ZSKDQJSQEBEQNE-UHFFFAOYSA-N 109647 US8609715, A-55 Enteropeptidase Homo sapiens 1.3 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109647&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242094 186526517 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229998 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCP(O)(O)=O InChI=1S/C17H20N3O7P/c1-10(16(21)20-9-28(23,24)25)8-13-6-7-14(26-13)17(22)27-12-4-2-11(3-5-12)15(18)19/h2-7,10H,8-9H2,1H3,(H3,18,19)(H,20,21)(H2,23,24,25) UQJFWFIQOFOONB-UHFFFAOYSA-N 109648 US8609715, A-56 Enteropeptidase Homo sapiens 1.1 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109648&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982998 186526518 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 229999 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O InChI=1S/C19H21N3O9S/c1-10(17(23)22-14(18(24)25)9-32(27,28)29)8-13-6-7-15(30-13)19(26)31-12-4-2-11(3-5-12)16(20)21/h2-7,10,14H,8-9H2,1H3,(H3,20,21)(H,22,23)(H,24,25)(H,27,28,29)/t10?,14-/m0/s1 GMPGZCBUDQFBOG-SBNLOKMTSA-N 109649 US8609715, A-57 Enteropeptidase Homo sapiens 0.39 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109649&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242095 186526519 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230000 CC(CCC(O)=O)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C18H20N2O5/c1-11(2-9-16(21)22)10-14-7-8-15(24-14)18(23)25-13-5-3-12(4-6-13)17(19)20/h3-8,11H,2,9-10H2,1H3,(H3,19,20)(H,21,22) CJKXPYNCSTWWBN-UHFFFAOYSA-N 109650 US8609715, A-58 Enteropeptidase Homo sapiens 0.70 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109650&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320312 186526520 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230001 CC(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H25N3O8/c1-12(2-9-18(26)25-16(21(29)30)11-19(27)28)10-15-7-8-17(32-15)22(31)33-14-5-3-13(4-6-14)20(23)24/h3-8,12,16H,2,9-11H2,1H3,(H3,23,24)(H,25,26)(H,27,28)(H,29,30)/t12?,16-/m0/s1 DNTBEYIBOAUAAQ-INSVYWFGSA-N 109651 US8609715, A-59 Enteropeptidase Homo sapiens 0.35 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109651&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320313 186526521 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230002 NC(=N)c1ccc(OC(=O)c2ccc(CC(CCC(O)=O)C(O)=O)o2)cc1 InChI=1S/C18H18N2O7/c19-16(20)10-1-4-12(5-2-10)27-18(25)14-7-6-13(26-14)9-11(17(23)24)3-8-15(21)22/h1-2,4-7,11H,3,8-9H2,(H3,19,20)(H,21,22)(H,23,24) RNXYWZSBKYGCIA-UHFFFAOYSA-N 109652 US8609715, A-60 Enteropeptidase Homo sapiens 0.31 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109652&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320315 186526522 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230003 NC(=N)c1ccc(OC(=O)c2ccc(CC(CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(O)=O)o2)cc1 InChI=1S/C22H23N3O10/c23-19(24)11-1-4-13(5-2-11)35-22(33)16-7-6-14(34-16)9-12(3-8-17(26)27)20(30)25-15(21(31)32)10-18(28)29/h1-2,4-7,12,15H,3,8-10H2,(H3,23,24)(H,25,30)(H,26,27)(H,28,29)(H,31,32)/t12?,15-/m0/s1 XFSYPERSORGYFV-CVRLYYSRSA-N 109653 US8609715, A-61 Enteropeptidase Homo sapiens 0.42 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109653&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983004 186526523 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230004 CC(Cc1cc(co1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-15(19(27)28)8-16(24)25)6-14-7-12(9-30-14)20(29)31-13-4-2-11(3-5-13)17(21)22/h2-5,7,9-10,15H,6,8H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,15-/m0/s1 QJETVBPZMLIIAY-WRXSAAJRSA-N 109654 US8609715, A-62 Enteropeptidase Homo sapiens 2.1 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109654&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983006 186526524 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230005 CC(Cc1cc(co1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C16H15FN2O5/c1-8(15(20)21)4-11-5-10(7-23-11)16(22)24-13-3-2-9(14(18)19)6-12(13)17/h2-3,5-8H,4H2,1H3,(H3,18,19)(H,20,21) MYTYNVXZNFHGKO-UHFFFAOYSA-N 109655 US8609715, A-63 Enteropeptidase Homo sapiens 0.53 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109655&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320314 186526525 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230006 CC(Cc1cc(co1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCP(O)(O)=O InChI=1S/C17H20N3O7P/c1-10(16(21)20-9-28(23,24)25)6-14-7-12(8-26-14)17(22)27-13-4-2-11(3-5-13)15(18)19/h2-5,7-8,10H,6,9H2,1H3,(H3,18,19)(H,20,21)(H2,23,24,25) LOWLDMCYLNRGLG-UHFFFAOYSA-N 109656 US8609715, A-64 Enteropeptidase Homo sapiens 2.5 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109656&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320317 186526526 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230007 CC(Cc1cc(co1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O InChI=1S/C19H21N3O9S/c1-10(17(23)22-15(18(24)25)9-32(27,28)29)6-14-7-12(8-30-14)19(26)31-13-4-2-11(3-5-13)16(20)21/h2-5,7-8,10,15H,6,9H2,1H3,(H3,20,21)(H,22,23)(H,24,25)(H,27,28,29)/t10?,15-/m0/s1 IQPXYZGNZYHQQF-WRXSAAJRSA-N 109657 US8609715, A-65 Enteropeptidase Homo sapiens 1.0 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109657&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983010 186526527 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230008 CC(Cc1cc(co1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O8/c1-9(18(27)24-14(19(28)29)7-16(25)26)4-12-5-11(8-31-12)20(30)32-15-3-2-10(17(22)23)6-13(15)21/h2-3,5-6,8-9,14H,4,7H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,14-/m0/s1 WPJPRSALESMYJQ-RJSPSEDBSA-N 109658 US8609715, A-66 Enteropeptidase Homo sapiens 0.32 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109658&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983012 186526528 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230009 CC(Cc1coc(c1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O8/c1-10(18(26)23-14(19(27)28)8-16(24)25)6-11-7-15(30-9-11)20(29)31-13-4-2-12(3-5-13)17(21)22/h2-5,7,9-10,14H,6,8H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m0/s1 GLUNNQRGCXKATF-SBNLOKMTSA-N 109659 US8609715, A-67 Enteropeptidase Homo sapiens 0.52 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109659&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983014 186526529 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230010 NC(=N)c1ccc(OC(=O)c2ccc(o2)-c2ccc(cc2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C23H19N3O8/c24-20(25)13-5-7-15(8-6-13)33-23(32)18-10-9-17(34-18)12-1-3-14(4-2-12)21(29)26-16(22(30)31)11-19(27)28/h1-10,16H,11H2,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t16-/m0/s1 BLKGMXVBRRZSBK-INIZCTEOSA-N 109660 US8609715, A-68 Enteropeptidase Homo sapiens 2.2 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109660&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983016 186526530 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230011 NC(=N)c1ccc(OC(=O)c2ccc(o2)-c2ccc(cc2)C(=O)NCC(O)=O)cc1 InChI=1S/C21H17N3O6/c22-19(23)13-5-7-15(8-6-13)29-21(28)17-10-9-16(30-17)12-1-3-14(4-2-12)20(27)24-11-18(25)26/h1-10H,11H2,(H3,22,23)(H,24,27)(H,25,26) CZBSDTNUHWITEX-UHFFFAOYSA-N 109661 US8609715, A-69 Enteropeptidase Homo sapiens 4.7 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109661&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983018 186526531 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230012 NC(=N)c1ccc(OC(=O)c2ccc(o2)-c2ccc(cc2)C(=O)NCP(O)(O)=O)cc1 InChI=1S/C20H18N3O7P/c21-18(22)13-5-7-15(8-6-13)29-20(25)17-10-9-16(30-17)12-1-3-14(4-2-12)19(24)23-11-31(26,27)28/h1-10H,11H2,(H3,21,22)(H,23,24)(H2,26,27,28) MACKSNDBMYURRZ-UHFFFAOYSA-N 109662 US8609715, A-70 Enteropeptidase Homo sapiens 2.7 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109662&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983020 186526532 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230013 NC(=N)c1ccc(OC(=O)c2ccc(o2)-c2cccc(c2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C23H19N3O8/c24-20(25)12-4-6-15(7-5-12)33-23(32)18-9-8-17(34-18)13-2-1-3-14(10-13)21(29)26-16(22(30)31)11-19(27)28/h1-10,16H,11H2,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t16-/m0/s1 AHMVMZSRXLKIHQ-INIZCTEOSA-N 109663 US8609715, A-71 Enteropeptidase Homo sapiens 1.6 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109663&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 89048945 186526533 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230014 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)O[C@H](CC(O)=O)C(O)=O InChI=1S/C20H20N2O9/c1-10(19(27)31-15(18(25)26)9-16(23)24)8-13-6-7-14(29-13)20(28)30-12-4-2-11(3-5-12)17(21)22/h2-7,10,15H,8-9H2,1H3,(H3,21,22)(H,23,24)(H,25,26)/t10?,15-/m1/s1 SHOHSFAXTYSWOS-GENIYJEYSA-N 109664 US8609715, A-72 Enteropeptidase Homo sapiens 0.68 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109664&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320273 186526534 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230015 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)SC(CC(O)=O)C(O)=O InChI=1S/C20H20N2O8S/c1-10(20(28)31-15(18(25)26)9-16(23)24)8-13-6-7-14(29-13)19(27)30-12-4-2-11(3-5-12)17(21)22/h2-7,10,15H,8-9H2,1H3,(H3,21,22)(H,23,24)(H,25,26) MFFDPIJWPIGJHU-UHFFFAOYSA-N 109665 US8609715, A-73 Enteropeptidase Homo sapiens 0.88 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109665&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983023 186526535 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230016 CC(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NN(CC(O)=O)CC(O)=O InChI=1S/C20H22N4O8/c1-11(19(29)23-24(9-16(25)26)10-17(27)28)8-14-6-7-15(31-14)20(30)32-13-4-2-12(3-5-13)18(21)22/h2-7,11H,8-10H2,1H3,(H3,21,22)(H,23,29)(H,25,26)(H,27,28) VEXHIVBEBWRFJD-UHFFFAOYSA-N 109666 US8609715, A-74 Enteropeptidase Homo sapiens 2.6 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109666&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983025 186526536 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230017 C\C(=C/c1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCC(O)=O InChI=1S/C18H17N3O5S/c1-10(17(24)21-9-15(22)23)8-13-6-7-14(27-13)18(25)26-12-4-2-11(3-5-12)16(19)20/h2-8H,9H2,1H3,(H3,19,20)(H,21,24)(H,22,23)/b10-8+ ORIXUOJACQINEN-CSKARUKUSA-N 109618 US8609715, B-2 Enteropeptidase Homo sapiens 9.29 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109618&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982956 186526488 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230018 C\C(=C/c1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C19H19N3O6S/c1-10(17(24)22-14(9-23)18(25)26)8-13-6-7-15(29-13)19(27)28-12-4-2-11(3-5-12)16(20)21/h2-8,14,23H,9H2,1H3,(H3,20,21)(H,22,24)(H,25,26)/b10-8+/t14-/m0/s1 YYWBBLNCZBADRS-PLWJUESGSA-N 109619 US8609715, B-3 Enteropeptidase Homo sapiens 5.72 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109619&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982958 186526489 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230019 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C16H16N2O4S/c1-9(15(19)20)8-12-6-7-13(23-12)16(21)22-11-4-2-10(3-5-11)14(17)18/h2-7,9H,8H2,1H3,(H3,17,18)(H,19,20) OSXWFMAUTQKVIB-UHFFFAOYSA-N 109620 US8609715, B-6 Enteropeptidase Homo sapiens 1.44 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109620&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320283 186526490 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230020 C\C(=C/c1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCCO)CCS(O)(=O)=O InChI=1S/C21H25N3O7S2/c1-14(20(26)24(9-2-11-25)10-12-33(28,29)30)13-17-7-8-18(32-17)21(27)31-16-5-3-15(4-6-16)19(22)23/h3-8,13,25H,2,9-12H2,1H3,(H3,22,23)(H,28,29,30)/b14-13+ HESPFXXTEAPSNR-BUHFOSPRSA-N 109621 US8609715, B-7 Enteropeptidase Homo sapiens 2.15 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109621&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982961 186526491 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230021 C\C(=C/c1ccc(s1)C(=O)Oc1ccc(cc1[N+]([O-])=O)C(N)=N)C(O)=O InChI=1S/C16H13N3O6S/c1-8(15(20)21)6-10-3-5-13(26-10)16(22)25-12-4-2-9(14(17)18)7-11(12)19(23)24/h2-7H,1H3,(H3,17,18)(H,20,21)/b8-6+ YIGYWYRLQOYYSK-SOFGYWHQSA-N 109622 US8609715, B-8 Enteropeptidase Homo sapiens 0.84 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109622&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982963 186526492 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230022 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1[N+]([O-])=O)C(N)=N)C(=O)N(CCCO)CC(O)=O InChI=1S/C21H24N4O8S/c1-12(20(29)24(7-2-8-26)11-18(27)28)9-14-4-6-17(34-14)21(30)33-16-5-3-13(19(22)23)10-15(16)25(31)32/h3-6,10,12,26H,2,7-9,11H2,1H3,(H3,22,23)(H,27,28) UMKDPGBFQCLKCM-UHFFFAOYSA-N 109623 US8609715, B-11 Enteropeptidase Homo sapiens 1.41 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109623&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982965 186526493 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230023 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCC(O)=O InChI=1S/C18H19N3O5S/c1-10(17(24)21-9-15(22)23)8-13-6-7-14(27-13)18(25)26-12-4-2-11(3-5-12)16(19)20/h2-7,10H,8-9H2,1H3,(H3,19,20)(H,21,24)(H,22,23) ISYNRVLFJWYDPA-UHFFFAOYSA-N 109624 US8609715, B-12 Enteropeptidase Homo sapiens 2.21 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109624&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320275 186526494 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230024 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1Br)C(N)=N)C(O)=O InChI=1S/C16H15BrN2O4S/c1-8(15(20)21)6-10-3-5-13(24-10)16(22)23-12-4-2-9(14(18)19)7-11(12)17/h2-5,7-8H,6H2,1H3,(H3,18,19)(H,20,21) CVTFPJOXXMGELG-UHFFFAOYSA-N 109625 US8609715, B-16 Enteropeptidase Homo sapiens 0.29 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109625&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320276 186526495 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230025 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1Cl)C(N)=N)C(O)=O InChI=1S/C16H15ClN2O4S/c1-8(15(20)21)6-10-3-5-13(24-10)16(22)23-12-4-2-9(14(18)19)7-11(12)17/h2-5,7-8H,6H2,1H3,(H3,18,19)(H,20,21) LRYCCXCWOKPCPE-UHFFFAOYSA-N 109626 US8609715, B-17 Enteropeptidase Homo sapiens 0.42 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109626&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74982969 186526496 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230026 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O7S/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(31-13)20(29)30-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m0/s1 ROLFUJWXUIPIFT-SBNLOKMTSA-N 109627 US8609715, B-18 Enteropeptidase Homo sapiens 1.36 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109627&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320271 186526497 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230027 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C16H15FN2O4S/c1-8(15(20)21)6-10-3-5-13(24-10)16(22)23-12-4-2-9(14(18)19)7-11(12)17/h2-5,7-8H,6H2,1H3,(H3,18,19)(H,20,21) XSTMCTGXVAPZAT-UHFFFAOYSA-N 109628 US8609715, B-19 Enteropeptidase Homo sapiens 0.42 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109628&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320249 186526498 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230028 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O7S/c1-9(18(27)24-13(19(28)29)8-16(25)26)6-11-3-5-15(32-11)20(30)31-14-4-2-10(17(22)23)7-12(14)21/h2-5,7,9,13H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,13-/m0/s1 CAZDAAGVXGRUJG-NCWAPJAISA-N 109629 US8609715, B-20 Enteropeptidase Homo sapiens 0.28 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109629&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242090 186526499 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230029 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C21H22FN3O7S/c1-10(19(28)25-14(20(29)30)4-7-17(26)27)8-12-3-6-16(33-12)21(31)32-15-5-2-11(18(23)24)9-13(15)22/h2-3,5-6,9-10,14H,4,7-8H2,1H3,(H3,23,24)(H,25,28)(H,26,27)(H,29,30)/t10?,14-/m0/s1 AOURNCMLYSCKQM-SBNLOKMTSA-N 109630 US8609715, B-21 Enteropeptidase Homo sapiens 0.56 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109630&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242082 186526500 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230030 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O7S/c1-9(18(27)24-13(19(28)29)8-16(25)26)6-11-3-5-15(32-11)20(30)31-14-4-2-10(17(22)23)7-12(14)21/h2-5,7,9,13H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,13-/m1/s1 CAZDAAGVXGRUJG-WCRCJTMVSA-N 109631 US8609715, B-22 Enteropeptidase Homo sapiens 0.50 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109631&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242083 186526501 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230031 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O7S/c1-10(18(26)23-14(19(27)28)9-16(24)25)8-13-6-7-15(31-13)20(29)30-12-4-2-11(3-5-12)17(21)22/h2-7,10,14H,8-9H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m1/s1 ROLFUJWXUIPIFT-LNUXAPHWSA-N 109632 US8609715, B-23 Enteropeptidase Homo sapiens 1.47 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109632&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242084 186526502 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230032 CC(Cc1ccc(s1)C(=O)Oc1ccc(C(N)=N)c(F)c1)C(O)=O InChI=1S/C16H15FN2O4S/c1-8(15(20)21)6-10-3-5-13(24-10)16(22)23-9-2-4-11(14(18)19)12(17)7-9/h2-5,7-8H,6H2,1H3,(H3,18,19)(H,20,21) RKCUDMPDZXZHNG-UHFFFAOYSA-N 109633 US8609715, B-24 Enteropeptidase Homo sapiens 0.49 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109633&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320247 186526503 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230033 C[C@H](Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O7S/c1-9(18(27)24-13(19(28)29)8-16(25)26)6-11-3-5-15(32-11)20(30)31-14-4-2-10(17(22)23)7-12(14)21/h2-5,7,9,13H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9-,13+/m1/s1 CAZDAAGVXGRUJG-RNCFNFMXSA-N 109668 US8609715, B-25 Enteropeptidase Homo sapiens 0.79 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109668&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242115 186526538 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230034 CC(C)C[C@H](Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-11(2)7-13(21(30)27-16(22(31)32)10-19(28)29)8-14-4-6-18(35-14)23(33)34-17-5-3-12(20(25)26)9-15(17)24/h3-6,9,11,13,16H,7-8,10H2,1-2H3,(H3,25,26)(H,27,30)(H,28,29)(H,31,32)/t13-,16+/m1/s1 JRFWEPKREKVKLE-CJNGLKHVSA-N 109669 US8609715, B-26 Enteropeptidase Homo sapiens 2.2 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109669&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242098 186526539 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230035 CC(C)C[C@@H](Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-11(2)7-13(21(30)27-16(22(31)32)10-19(28)29)8-14-4-6-18(35-14)23(33)34-17-5-3-12(20(25)26)9-15(17)24/h3-6,9,11,13,16H,7-8,10H2,1-2H3,(H3,25,26)(H,27,30)(H,28,29)(H,31,32)/t13-,16-/m0/s1 JRFWEPKREKVKLE-BBRMVZONSA-N 109670 US8609715, B-27 Enteropeptidase Homo sapiens 0.95 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109670&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242099 186526540 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230036 CCC[C@H](Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C22H24FN3O7S/c1-2-3-12(20(29)26-15(21(30)31)10-18(27)28)8-13-5-7-17(34-13)22(32)33-16-6-4-11(19(24)25)9-14(16)23/h4-7,9,12,15H,2-3,8,10H2,1H3,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t12-,15+/m1/s1 DCNHFHNFBDBZOO-DOMZBBRYSA-N 109671 US8609715, B-28 Enteropeptidase Homo sapiens 1.1 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109671&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242100 186526541 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230037 CCC[C@@H](Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C22H24FN3O7S/c1-2-3-12(20(29)26-15(21(30)31)10-18(27)28)8-13-5-7-17(34-13)22(32)33-16-6-4-11(19(24)25)9-14(16)23/h4-7,9,12,15H,2-3,8,10H2,1H3,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t12-,15-/m0/s1 DCNHFHNFBDBZOO-WFASDCNBSA-N 109672 US8609715, B-29 Enteropeptidase Homo sapiens 0.58 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109672&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242101 186526542 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230039 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1Cl)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20ClN3O7S/c1-9(18(27)24-13(19(28)29)8-16(25)26)6-11-3-5-15(32-11)20(30)31-14-4-2-10(17(22)23)7-12(14)21/h2-5,7,9,13H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,13-/m0/s1 LUUHMTNJGRGXDT-NCWAPJAISA-N 109674 US8609715, B-31 Enteropeptidase Homo sapiens 0.33 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109674&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242116 186526544 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230040 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C19H18FN3O7S/c20-11-7-9(17(21)22)1-4-13(11)30-19(29)14-5-2-10(31-14)3-6-15(24)23-12(18(27)28)8-16(25)26/h1-2,4-5,7,12H,3,6,8H2,(H3,21,22)(H,23,24)(H,25,26)(H,27,28)/t12-/m0/s1 HCTJKQXXQCXJBI-LBPRGKRZSA-N 109675 US8609715, B-32 Enteropeptidase Homo sapiens 0.31 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109675&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242117 186526545 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230041 CCCC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C22H25N3O7S/c1-2-3-13(20(28)25-16(21(29)30)11-18(26)27)10-15-8-9-17(33-15)22(31)32-14-6-4-12(5-7-14)19(23)24/h4-9,13,16H,2-3,10-11H2,1H3,(H3,23,24)(H,25,28)(H,26,27)(H,29,30)/t13?,16-/m0/s1 HPZAOOFNYDCJTF-VYIIXAMBSA-N 109676 US8609715, B-33 Enteropeptidase Homo sapiens 2.8 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109676&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242118 186526546 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230042 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCCC(C1)C(O)=O InChI=1S/C22H24FN3O5S/c1-12(20(27)26-8-2-3-14(11-26)21(28)29)9-15-5-7-18(32-15)22(30)31-17-6-4-13(19(24)25)10-16(17)23/h4-7,10,12,14H,2-3,8-9,11H2,1H3,(H3,24,25)(H,28,29) NVELFZVOVGFYMQ-UHFFFAOYSA-N 109677 US8609715, B-34 Enteropeptidase Homo sapiens 2.2 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109677&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983038 186526547 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230043 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C19H20FN3O6S/c1-9(17(25)23-13(8-24)18(26)27)6-11-3-5-15(30-11)19(28)29-14-4-2-10(16(21)22)7-12(14)20/h2-5,7,9,13,24H,6,8H2,1H3,(H3,21,22)(H,23,25)(H,26,27)/t9?,13-/m0/s1 HFAXBOJZTCZEBE-NCWAPJAISA-N 109678 US8609715, B-35 Enteropeptidase Homo sapiens 0.40 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109678&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983040 186526548 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230044 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C19H18FN3O7S/c20-11-7-9(17(21)22)1-4-13(11)30-19(29)14-5-2-10(31-14)3-6-15(24)23-12(18(27)28)8-16(25)26/h1-2,4-5,7,12H,3,6,8H2,(H3,21,22)(H,23,24)(H,25,26)(H,27,28)/t12-/m1/s1 HCTJKQXXQCXJBI-GFCCVEGCSA-N 109679 US8609715, B-36 Enteropeptidase Homo sapiens 0.51 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109679&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242119 186526549 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230045 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(O)=O)CC(O)=O)s2)c(F)c1 InChI=1S/C20H20FN3O7S/c21-13-9-11(19(22)23)1-4-14(13)31-20(30)15-5-2-12(32-15)3-6-16(25)24(10-18(28)29)8-7-17(26)27/h1-2,4-5,9H,3,6-8,10H2,(H3,22,23)(H,26,27)(H,28,29) BPRMXTWEHUUNPK-UHFFFAOYSA-N 109680 US8609715, B-37 Enteropeptidase Homo sapiens 0.50 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109680&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983043 186526550 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230046 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)CC(O)=O)s2)c(F)c1 InChI=1S/C20H20FN3O5S/c1-2-9-24(11-18(26)27)17(25)8-5-13-4-7-16(30-13)20(28)29-15-6-3-12(19(22)23)10-14(15)21/h2-4,6-7,10H,1,5,8-9,11H2,(H3,22,23)(H,26,27) UZIOSSRZPQCJLE-UHFFFAOYSA-N 109681 US8609715, B-38 Enteropeptidase Homo sapiens 0.75 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109681&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242147 186526551 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230047 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O InChI=1S/C19H21N3O8S2/c1-10(17(23)22-14(18(24)25)9-32(27,28)29)8-13-6-7-15(31-13)19(26)30-12-4-2-11(3-5-12)16(20)21/h2-7,10,14H,8-9H2,1H3,(H3,20,21)(H,22,23)(H,24,25)(H,27,28,29)/t10?,14-/m0/s1 SJXWQWQXFQBIDH-SBNLOKMTSA-N 109682 US8609715, B-39 Enteropeptidase Homo sapiens 0.95 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109682&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242137 186526552 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230048 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)NCP(O)(O)=O InChI=1S/C17H20N3O6PS/c1-10(16(21)20-9-27(23,24)25)8-13-6-7-14(28-13)17(22)26-12-4-2-11(3-5-12)15(18)19/h2-7,10H,8-9H2,1H3,(H3,18,19)(H,20,21)(H2,23,24,25) XWELLMORAXLSNJ-UHFFFAOYSA-N 109683 US8609715, B-40 Enteropeptidase Homo sapiens 2.0 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109683&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983047 186526553 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230049 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O InChI=1S/C19H20FN3O8S2/c1-9(17(24)23-13(18(25)26)8-33(28,29)30)6-11-3-5-15(32-11)19(27)31-14-4-2-10(16(21)22)7-12(14)20/h2-5,7,9,13H,6,8H2,1H3,(H3,21,22)(H,23,24)(H,25,26)(H,28,29,30)/t9?,13-/m0/s1 ZDHSABZRIYUHBN-NCWAPJAISA-N 109684 US8609715, B-41 Enteropeptidase Homo sapiens 0.27 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109684&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242138 186526554 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230050 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCP(O)(O)=O InChI=1S/C17H19FN3O6PS/c1-9(16(22)21-8-28(24,25)26)6-11-3-5-14(29-11)17(23)27-13-4-2-10(15(19)20)7-12(13)18/h2-5,7,9H,6,8H2,1H3,(H3,19,20)(H,21,22)(H2,24,25,26) PJXAFQKIXSYHNC-UHFFFAOYSA-N 109685 US8609715, B-42 Enteropeptidase Homo sapiens 0.37 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109685&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983050 186526555 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230051 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1Cl)C(N)=N)C(=O)NCP(O)(O)=O InChI=1S/C17H19ClN3O6PS/c1-9(16(22)21-8-28(24,25)26)6-11-3-5-14(29-11)17(23)27-13-4-2-10(15(19)20)7-12(13)18/h2-5,7,9H,6,8H2,1H3,(H3,19,20)(H,21,22)(H2,24,25,26) AAVSQDISOQOCQY-UHFFFAOYSA-N 109686 US8609715, B-43 Enteropeptidase Homo sapiens 0.42 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109686&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983052 186526556 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230052 CC(Cc1ccc(s1)C(=O)Oc1ccc(cc1Cl)C(N)=N)C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O InChI=1S/C19H20ClN3O8S2/c1-9(17(24)23-13(18(25)26)8-33(28,29)30)6-11-3-5-15(32-11)19(27)31-14-4-2-10(16(21)22)7-12(14)20/h2-5,7,9,13H,6,8H2,1H3,(H3,21,22)(H,23,24)(H,25,26)(H,28,29,30)/t9?,13-/m0/s1 MKSOBCCFULRBLE-NCWAPJAISA-N 109687 US8609715, B-44 Enteropeptidase Homo sapiens 0.21 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109687&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242139 186526557 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230053 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C18H18FN3O8S2/c19-11-7-9(16(20)21)1-4-13(11)30-18(26)14-5-2-10(31-14)3-6-15(23)22-12(17(24)25)8-32(27,28)29/h1-2,4-5,7,12H,3,6,8H2,(H3,20,21)(H,22,23)(H,24,25)(H,27,28,29)/t12-/m0/s1 MASZGBXCAFOYGE-LBPRGKRZSA-N 109688 US8609715, B-45 Enteropeptidase Homo sapiens 0.48 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109688&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242140 186526558 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230054 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)NCP(O)(O)=O)s2)c(F)c1 InChI=1S/C16H17FN3O6PS/c17-11-7-9(15(18)19)1-4-12(11)26-16(22)13-5-2-10(28-13)3-6-14(21)20-8-27(23,24)25/h1-2,4-5,7H,3,6,8H2,(H3,18,19)(H,20,21)(H2,23,24,25) RJKCYNBEQOWJNI-UHFFFAOYSA-N 109689 US8609715, B-46 Enteropeptidase Homo sapiens 0.38 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109689&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983056 186526559 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230055 CC(CCC(O)=O)Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C18H20N2O4S/c1-11(2-9-16(21)22)10-14-7-8-15(25-14)18(23)24-13-5-3-12(4-6-13)17(19)20/h3-8,11H,2,9-10H2,1H3,(H3,19,20)(H,21,22) AHRMXPSSZCOPBH-UHFFFAOYSA-N 109690 US8609715, B-47 Enteropeptidase Homo sapiens 2.5 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109690&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983058 186526560 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230056 CC(CCC(O)=O)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C18H19FN2O4S/c1-10(2-7-16(22)23)8-12-4-6-15(26-12)18(24)25-14-5-3-11(17(20)21)9-13(14)19/h3-6,9-10H,2,7-8H2,1H3,(H3,20,21)(H,22,23) WNTDNXVHRKTOAJ-UHFFFAOYSA-N 109691 US8609715, B-48 Enteropeptidase Homo sapiens 0.88 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109691&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320250 186526561 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230057 CC(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H24FN3O7S/c1-11(2-7-18(27)26-15(21(30)31)10-19(28)29)8-13-4-6-17(34-13)22(32)33-16-5-3-12(20(24)25)9-14(16)23/h3-6,9,11,15H,2,7-8,10H2,1H3,(H3,24,25)(H,26,27)(H,28,29)(H,30,31)/t11?,15-/m0/s1 YSOABFZKTWHRBK-MHTVFEQDSA-N 109692 US8609715, B-49 Enteropeptidase Homo sapiens 0.41 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109692&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320252 186526562 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230058 CC(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)Cc1ccc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H25N3O7S/c1-12(2-9-18(26)25-16(21(29)30)11-19(27)28)10-15-7-8-17(33-15)22(31)32-14-5-3-13(4-6-14)20(23)24/h3-8,12,16H,2,9-11H2,1H3,(H3,23,24)(H,25,26)(H,27,28)(H,29,30)/t12?,16-/m0/s1 JHYSSLWVWDQGTD-INSVYWFGSA-N 109693 US8609715, B-50 Enteropeptidase Homo sapiens 0.89 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109693&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983062 186526563 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230059 CC(Cc1cc(cs1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C16H15FN2O4S/c1-8(15(20)21)4-11-5-10(7-24-11)16(22)23-13-3-2-9(14(18)19)6-12(13)17/h2-3,5-8H,4H2,1H3,(H3,18,19)(H,20,21) ZRQSXCHYQNMPCM-UHFFFAOYSA-N 109694 US8609715, B-51 Enteropeptidase Homo sapiens 0.72 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109694&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320251 186526564 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230060 CC(Cc1cc(cs1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O7S/c1-9(18(27)24-14(19(28)29)7-16(25)26)4-12-5-11(8-32-12)20(30)31-15-3-2-10(17(22)23)6-13(15)21/h2-3,5-6,8-9,14H,4,7H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,14-/m0/s1 WNIGXAAJIXADKE-RJSPSEDBSA-N 109695 US8609715, B-52 Enteropeptidase Homo sapiens 0.39 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109695&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983065 186526565 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230061 CC(Cc1cc(cs1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O7S/c1-10(18(26)23-15(19(27)28)8-16(24)25)6-14-7-12(9-31-14)20(29)30-13-4-2-11(3-5-13)17(21)22/h2-5,7,9-10,15H,6,8H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,15-/m0/s1 KZTWLZSQCPXGLA-WRXSAAJRSA-N 109696 US8609715, B-53 Enteropeptidase Homo sapiens 4.8 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109696&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983067 186526566 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230062 NC(=N)c1ccc(OC(=O)c2csc(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)c2)c(F)c1 InChI=1S/C19H18FN3O7S/c20-12-6-9(17(21)22)1-3-14(12)30-19(29)10-5-11(31-8-10)2-4-15(24)23-13(18(27)28)7-16(25)26/h1,3,5-6,8,13H,2,4,7H2,(H3,21,22)(H,23,24)(H,25,26)(H,27,28)/t13-/m0/s1 XPVJLTYZEKVRGR-ZDUSSCGKSA-N 109697 US8609715, B-54 Enteropeptidase Homo sapiens 0.58 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109697&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983069 186526567 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230063 CC(Cc1csc(c1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H21N3O7S/c1-10(18(26)23-14(19(27)28)8-16(24)25)6-11-7-15(31-9-11)20(29)30-13-4-2-12(3-5-13)17(21)22/h2-5,7,9-10,14H,6,8H2,1H3,(H3,21,22)(H,23,26)(H,24,25)(H,27,28)/t10?,14-/m0/s1 LNNRGSRYUTXGEX-SBNLOKMTSA-N 109698 US8609715, B-55 Enteropeptidase Homo sapiens 0.98 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109698&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983071 186526568 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230064 NC(=N)c1ccc(OC(=O)c2ccc(s2)-c2ccc(cc2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C23H19N3O7S/c24-20(25)13-5-7-15(8-6-13)33-23(32)18-10-9-17(34-18)12-1-3-14(4-2-12)21(29)26-16(22(30)31)11-19(27)28/h1-10,16H,11H2,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t16-/m0/s1 GLUIGFCYBVUXLM-INIZCTEOSA-N 109699 US8609715, B-56 Enteropeptidase Homo sapiens 9.5 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109699&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320281 186526569 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230065 NC(=N)c1ccc(OC(=O)c2ccc(s2)-c2ccc(cc2)C(=O)N[C@@H](CC(O)=O)C(O)=O)c(F)c1 InChI=1S/C23H18FN3O7S/c24-14-9-13(20(25)26)5-6-16(14)34-23(33)18-8-7-17(35-18)11-1-3-12(4-2-11)21(30)27-15(22(31)32)10-19(28)29/h1-9,15H,10H2,(H3,25,26)(H,27,30)(H,28,29)(H,31,32)/t15-/m0/s1 ALVURNATRNYWEF-HNNXBMFYSA-N 109700 US8609715, B-57 Enteropeptidase Homo sapiens 3.0 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109700&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983074 186526570 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230066 NC(=N)c1ccc(OC(=O)c2ccc(s2)-c2cccc(c2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C23H19N3O7S/c24-20(25)12-4-6-15(7-5-12)33-23(32)18-9-8-17(34-18)13-2-1-3-14(10-13)21(29)26-16(22(30)31)11-19(27)28/h1-10,16H,11H2,(H3,24,25)(H,26,29)(H,27,28)(H,30,31)/t16-/m0/s1 KXMIPQVSGMLEFS-INIZCTEOSA-N 109701 US8609715, B-58 Enteropeptidase Homo sapiens 9.8 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109701&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 89137823 186526571 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230067 NC(=N)c1ccc(OC(=O)c2ccc(s2)-c2ccc(s2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H17N3O7S2/c22-18(23)10-1-3-11(4-2-10)31-21(30)16-8-6-14(33-16)13-5-7-15(32-13)19(27)24-12(20(28)29)9-17(25)26/h1-8,12H,9H2,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t12-/m0/s1 WZUKLJJPQVYUOL-LBPRGKRZSA-N 109702 US8609715, B-59 Enteropeptidase Homo sapiens 8.2 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109702&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 89048802 186526572 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230068 NC(=N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C18H16FN3O7S/c19-10-5-8(16(20)21)1-3-12(10)29-18(28)13-4-2-9(30-13)6-14(23)22-11(17(26)27)7-15(24)25/h1-5,11H,6-7H2,(H3,20,21)(H,22,23)(H,24,25)(H,26,27)/t11-/m0/s1 TYOBWOMAXUPFNK-NSHDSACASA-N 109703 US8609715, B-60 Enteropeptidase Homo sapiens 0.64 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109703&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 89048864 186526573 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230069 Cc1cc(sc1CCC(=O)N[C@@H](CC(O)=O)C(O)=O)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H20FN3O7S/c1-9-6-15(20(30)31-13-3-2-10(18(22)23)7-11(13)21)32-14(9)4-5-16(25)24-12(19(28)29)8-17(26)27/h2-3,6-7,12H,4-5,8H2,1H3,(H3,22,23)(H,24,25)(H,26,27)(H,28,29)/t12-/m0/s1 KUFWXCZSAUGMIW-LBPRGKRZSA-N 109704 US8609715, B-61 Enteropeptidase Homo sapiens 0.13 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109704&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242141 186526574 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230070 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C20H20FN3O7S/c21-12-9-10(18(22)23)1-5-14(12)31-20(30)15-6-2-11(32-15)3-7-16(25)24-13(19(28)29)4-8-17(26)27/h1-2,5-6,9,13H,3-4,7-8H2,(H3,22,23)(H,24,25)(H,26,27)(H,28,29)/t13-/m0/s1 YIJFGJUDHTTZSG-ZDUSSCGKSA-N 109705 US8609715, B-62 Enteropeptidase Homo sapiens 0.57 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109705&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242142 186526575 C04305 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230071 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H22FN3O7S/c1-2-9-26(15(21(30)31)11-19(28)29)18(27)8-5-13-4-7-17(34-13)22(32)33-16-6-3-12(20(24)25)10-14(16)23/h2-4,6-7,10,15H,1,5,8-9,11H2,(H3,24,25)(H,28,29)(H,30,31)/t15-/m0/s1 DJFMRRLCDUSBOZ-HNNXBMFYSA-N 109706 US8609715, B-63 Enteropeptidase Homo sapiens 0.55 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109706&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242148 186526576 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230072 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C21H22FN3O7S/c1-21(2,20(31)25-13(18(28)29)8-16(26)27)9-11-4-6-15(33-11)19(30)32-14-5-3-10(17(23)24)7-12(14)22/h3-7,13H,8-9H2,1-2H3,(H3,23,24)(H,25,31)(H,26,27)(H,28,29)/t13-/m0/s1 NLKPKGISPLOPLB-ZDUSSCGKSA-N 109707 US8609715, B-64 Enteropeptidase Homo sapiens 0.14 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109707&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242149 186526577 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230073 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](Cc3ccc(O)cc3)C(O)=O)s2)c(F)c1 InChI=1S/C24H22FN3O6S/c25-17-12-14(22(26)27)3-8-19(17)34-24(33)20-9-6-16(35-20)7-10-21(30)28-18(23(31)32)11-13-1-4-15(29)5-2-13/h1-6,8-9,12,18,29H,7,10-11H2,(H3,26,27)(H,28,30)(H,31,32)/t18-/m0/s1 ITLSKYUNIVTASU-SFHVURJKSA-N 109708 US8609715, B-65 Enteropeptidase Homo sapiens 3.20 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109708&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983080 186526578 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230074 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CO)C(O)=O)s2)c(F)c1 InChI=1S/C18H18FN3O6S/c19-11-7-9(16(20)21)1-4-13(11)28-18(27)14-5-2-10(29-14)3-6-15(24)22-12(8-23)17(25)26/h1-2,4-5,7,12,23H,3,6,8H2,(H3,20,21)(H,22,24)(H,25,26)/t12-/m0/s1 ONSZHUQRQGYDFS-LBPRGKRZSA-N 109709 US8609715, B-66 Enteropeptidase Homo sapiens 0.73 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109709&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 68320277 186526579 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230075 C\C(=C/c1nc(cs1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N(CCCO)CC(O)=O InChI=1S/C20H22N4O6S/c1-12(19(28)24(7-2-8-25)10-17(26)27)9-16-23-15(11-31-16)20(29)30-14-5-3-13(4-6-14)18(21)22/h3-6,9,11,25H,2,7-8,10H2,1H3,(H3,21,22)(H,26,27)/b12-9+ SBYSYEMARSDRIB-FMIVXFBMSA-N 109667 US8609715, C-2 Enteropeptidase Homo sapiens 5.67 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109667&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983027 186526537 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230076 CC(Cc1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H19FN4O7S/c1-8(17(27)24-11(18(28)29)6-15(25)26)4-14-23-7-13(32-14)19(30)31-12-3-2-9(16(21)22)5-10(12)20/h2-3,5,7-8,11H,4,6H2,1H3,(H3,21,22)(H,24,27)(H,25,26)(H,28,29)/t8?,11-/m0/s1 DBKBHOJMFKSRDI-LYNSQETBSA-N 109710 US8609715, C-4 Enteropeptidase Homo sapiens 3.7 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109710&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 74983083 186526580 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 230038 CC(Cc1ccc(s1)C(=O)Oc1ccc(C(N)=N)c(F)c1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20FN3O7S/c1-9(18(27)24-14(19(28)29)8-16(25)26)6-11-3-5-15(32-11)20(30)31-10-2-4-12(17(22)23)13(21)7-10/h2-5,7,9,14H,6,8H2,1H3,(H3,22,23)(H,24,27)(H,25,26)(H,28,29)/t9?,14-/m0/s1 ZOLQRFPIPJIMES-RJSPSEDBSA-N 109673 US8609715, B-30 Enteropeptidase Homo sapiens 0.52 US Patent 10.7270/Q2Z31X9X aid1800245 US8609715 Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=109673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=109673&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 53242102 186526543 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300353 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/m0/s1 CHAXFLSDNLDWPP-AWEZNQCLSA-N 158073 US9024044, 1::US9227949, 1::US9655879, 1 Enteropeptidase Homo sapiens 0.14 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158073&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699917 254815267 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300354 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C23H24FN3O7S/c24-14-9-12(19(25)26)3-5-16(14)34-21(32)17-6-4-13(35-17)11-23(7-1-2-8-23)22(33)27-15(20(30)31)10-18(28)29/h3-6,9,15H,1-2,7-8,10-11H2,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m0/s1 HXDKJHJAMFQXBA-HNNXBMFYSA-N 158074 US9024044, 2::US9227949, 2::US9655879, 2 Enteropeptidase Homo sapiens 0.73 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158074&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90019132 254815268 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300355 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O InChI=1S/C19H20FN3O5S/c1-19(2,18(27)23-9-15(24)25)8-11-4-6-14(29-11)17(26)28-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,27)(H,24,25) FBFZNZYSXBOYCU-UHFFFAOYSA-N 158075 US9024044, 3::US9227949, 3 Enteropeptidase Homo sapiens 0.29 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158075&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699918 254815269 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300356 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C20H22FN3O6S/c1-20(2,19(29)24-13(9-25)17(26)27)8-11-4-6-15(31-11)18(28)30-14-5-3-10(16(22)23)7-12(14)21/h3-7,13,25H,8-9H2,1-2H3,(H3,22,23)(H,24,29)(H,26,27)/t13-/m0/s1 PGOXWLZRNRRTHV-ZDUSSCGKSA-N 158076 US9024044, 4::US9227949, 4::US9655879, 4 Enteropeptidase Homo sapiens 0.46 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158076&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699919 254815270 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300357 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28) XYNSVADDWDUDBJ-UHFFFAOYSA-N 158077 US9024044, 5::US9227949, 5::US9655879, 5 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158077&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699920 254815271 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300358 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(C)(C)C(O)=O InChI=1S/C21H24FN3O5S/c1-20(2,18(27)25-21(3,4)19(28)29)10-12-6-8-15(31-12)17(26)30-14-7-5-11(16(23)24)9-13(14)22/h5-9H,10H2,1-4H3,(H3,23,24)(H,25,27)(H,28,29) CXAAAVDPZVTHHD-UHFFFAOYSA-N 158078 US9024044, 6::US9227949, 6::US9655879, 6 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158078&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699921 254815272 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300359 CN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H22FN3O5S/c1-20(2,19(28)24(3)10-16(25)26)9-12-5-7-15(30-12)18(27)29-14-6-4-11(17(22)23)8-13(14)21/h4-8H,9-10H2,1-3H3,(H3,22,23)(H,25,26) LWAVAXQFRSKGMV-UHFFFAOYSA-N 158079 US9024044, 7::US9227949, 7::US9655879, 7 Enteropeptidase Homo sapiens 0.41 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158079&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044933 254815273 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300360 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C22H24FN3O5S/c1-22(2,21(30)26-9-3-4-15(26)19(27)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23/h5-8,10,15H,3-4,9,11H2,1-2H3,(H3,24,25)(H,27,28)/t15-/m0/s1 BBMBOQSWYMFNGF-HNNXBMFYSA-N 158080 US9024044, 8::US9227949, 8 Enteropeptidase Homo sapiens 0.87 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158080&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044934 254815274 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300361 CC(C)[C@H](NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C22H26FN3O5S/c1-11(2)17(19(27)28)26-21(30)22(3,4)10-13-6-8-16(32-13)20(29)31-15-7-5-12(18(24)25)9-14(15)23/h5-9,11,17H,10H2,1-4H3,(H3,24,25)(H,26,30)(H,27,28)/t17-/m0/s1 WDNTXANUISNDIT-KRWDZBQOSA-N 158081 US9024044, 9::US9227949, 9 Enteropeptidase Homo sapiens 0.79 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158081&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018773 254815275 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300362 CCCN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H26FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h5-8,10H,4,9,11-12H2,1-3H3,(H3,24,25)(H,27,28) VCKIEANVSOSDBH-UHFFFAOYSA-N 158082 US9024044, 10::US9227949, 10 Enteropeptidase Homo sapiens 0.49 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158082&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699992 254815276 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300363 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C22H26FN3O6S/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29)/t15-/m0/s1 LFSLIAZOFSRRDB-HNNXBMFYSA-N 158083 US9024044, 11::US9227949, 11 Enteropeptidase Homo sapiens 0.41 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158083&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699993 254815277 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300364 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CO)C(O)=O InChI=1S/C22H26FN3O6S/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29)/t15-/m1/s1 LFSLIAZOFSRRDB-OAHLLOKOSA-N 158084 US9024044, 12::US9227949, 12 Enteropeptidase Homo sapiens 0.94 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158084&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044935 254815278 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300365 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C24H30FN3O5S/c1-5-24(6-2,23(32)28-19(13(3)4)21(29)30)12-15-8-10-18(34-15)22(31)33-17-9-7-14(20(26)27)11-16(17)25/h7-11,13,19H,5-6,12H2,1-4H3,(H3,26,27)(H,28,32)(H,29,30)/t19-/m0/s1 QCKHQIYRKNPRBR-IBGZPJMESA-N 158085 US9024044, 13::US9227949, 13 Enteropeptidase Homo sapiens 1.56 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158085&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699994 254815279 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300366 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC(O)=O InChI=1S/C22H26FN3O5S/c1-3-22(4-2,21(30)26-10-9-18(27)28)12-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)11-15(16)23/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,24,25)(H,26,30)(H,27,28) RMZDNEFSCYWLFZ-UHFFFAOYSA-N 158086 US9024044, 14::US9227949, 14 Enteropeptidase Homo sapiens 0.99 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158086&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699995 254815280 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300367 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)O)C(O)=O InChI=1S/C23H28FN3O6S/c1-4-23(5-2,22(32)27-18(12(3)28)20(29)30)11-14-7-9-17(34-14)21(31)33-16-8-6-13(19(25)26)10-15(16)24/h6-10,12,18,28H,4-5,11H2,1-3H3,(H3,25,26)(H,27,32)(H,29,30)/t12?,18-/m0/s1 JKNBTSMKSSJRDC-ZJFPTPTDSA-N 158087 US9024044, 15::US9227949, 15 Enteropeptidase Homo sapiens 0.84 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158087&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044936 254815281 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300368 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C28H30FN3O5S/c1-3-28(4-2,27(36)32-21(25(33)34)14-17-8-6-5-7-9-17)16-19-11-13-23(38-19)26(35)37-22-12-10-18(24(30)31)15-20(22)29/h5-13,15,21H,3-4,14,16H2,1-2H3,(H3,30,31)(H,32,36)(H,33,34)/t21-/m0/s1 PGPODLSJZFFJCS-NRFANRHFSA-N 158088 US9024044, 16::US9227949, 16 Enteropeptidase Homo sapiens 1.1 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158088&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044937 254815282 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300369 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C24H28FN3O5S/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30)/t17-/m0/s1 PJQIIQDUTSQWIS-KRWDZBQOSA-N 158089 US9024044, 17::US9227949, 17 Enteropeptidase Homo sapiens 1.69 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158089&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044938 254815283 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300370 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C19H21FN2O4S/c1-3-19(4-2,18(24)25)10-12-6-8-15(27-12)17(23)26-14-7-5-11(16(21)22)9-13(14)20/h5-9H,3-4,10H2,1-2H3,(H3,21,22)(H,24,25) NVBTXQNZNQVUIV-UHFFFAOYSA-N 158090 US9024044, 18::US9227949, 18::US9655879, 18 Enteropeptidase Homo sapiens 1.24 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158090&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699996 254815284 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300371 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m0/s1 IBHPUOCNUKPTBM-HNNXBMFYSA-N 158091 US9024044, 19::US9227949, 19 Enteropeptidase Homo sapiens 0.33 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158091&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72543744 254815285 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300372 CCCN(CC(O)=O)C(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C24H30FN3O5S/c1-4-11-28(14-20(29)30)23(32)24(5-2,6-3)13-16-8-10-19(34-16)22(31)33-18-9-7-15(21(26)27)12-17(18)25/h7-10,12H,4-6,11,13-14H2,1-3H3,(H3,26,27)(H,29,30) QRSQMHVQHCFHOA-UHFFFAOYSA-N 158092 US9024044, 20::US9227949, 20 Enteropeptidase Homo sapiens 2.61 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158092&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044939 254815286 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300373 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(C)CC(O)=O InChI=1S/C22H26FN3O5S/c1-4-22(5-2,21(30)26(3)12-18(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(19(24)25)10-15(16)23/h6-10H,4-5,11-12H2,1-3H3,(H3,24,25)(H,27,28) JGFFFJLERKVFRG-UHFFFAOYSA-N 158093 US9024044, 21::US9227949, 21 Enteropeptidase Homo sapiens 0.88 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158093&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018822 254815287 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300374 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@@H]1C(O)=O InChI=1S/C24H28FN3O5S/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30)/t17-/m1/s1 PJQIIQDUTSQWIS-QGZVFWFLSA-N 158094 US9024044, 22::US9227949, 22 Enteropeptidase Homo sapiens 1 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158094&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044940 254815288 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300375 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CCS(O)(=O)=O)CC=C InChI=1S/C22H26FN3O6S2/c1-4-9-26(10-11-34(29,30)31)21(28)22(2,3)13-15-6-8-18(33-15)20(27)32-17-7-5-14(19(24)25)12-16(17)23/h4-8,12H,1,9-11,13H2,2-3H3,(H3,24,25)(H,29,30,31) DULSYBFZNKGICA-UHFFFAOYSA-N 158095 US9024044, 23::US9227949, 23::US9655879, 23 Enteropeptidase Homo sapiens 1.81 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158095&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90017966 254815289 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300376 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/m0/s1 MRDGTXNCJIRKAP-INIZCTEOSA-N 158096 US9024044, 24::US9227949, 24 Enteropeptidase Homo sapiens 0.27 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158096&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700069 254815290 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300377 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m1/s1 IBHPUOCNUKPTBM-OAHLLOKOSA-N 158097 US9024044, 25::US9227949, 25 Enteropeptidase Homo sapiens 0.26 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158097&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044941 254815291 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300378 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27-9-7-13(8-10-27)20(28)29)12-15-4-6-18(33-15)21(30)32-17-5-3-14(19(25)26)11-16(17)24/h3-6,11,13H,7-10,12H2,1-2H3,(H3,25,26)(H,28,29) JKGGZKLIDGJKFW-UHFFFAOYSA-N 158098 US9024044, 26::US9227949, 26 Enteropeptidase Homo sapiens 1.33 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158098&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044942 254815292 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300379 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C)C(O)=O InChI=1S/C22H26FN3O5S/c1-4-22(5-2,21(30)26-12(3)19(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(18(24)25)10-15(16)23/h6-10,12H,4-5,11H2,1-3H3,(H3,24,25)(H,26,30)(H,27,28)/t12-/m0/s1 WHADCIUXAGXHJQ-LBPRGKRZSA-N 158099 US9024044, 27::US9227949, 27 Enteropeptidase Homo sapiens 0.73 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158099&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044943 254815293 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300380 CC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C23H28FN3O5S/c1-4-16(20(28)29)27-22(31)23(5-2,6-3)12-14-8-10-18(33-14)21(30)32-17-9-7-13(19(25)26)11-15(17)24/h7-11,16H,4-6,12H2,1-3H3,(H3,25,26)(H,27,31)(H,28,29)/t16-/m0/s1 WSPUTIGUOKODRG-INIZCTEOSA-N 158100 US9024044, 28::US9227949, 28 Enteropeptidase Homo sapiens 0.65 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158100&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700066 254815294 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300381 CCC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C24H30FN3O5S/c1-4-7-17(21(29)30)28-23(32)24(5-2,6-3)13-15-9-11-19(34-15)22(31)33-18-10-8-14(20(26)27)12-16(18)25/h8-12,17H,4-7,13H2,1-3H3,(H3,26,27)(H,28,32)(H,29,30)/t17-/m0/s1 AGFHBSKFKFQJEM-KRWDZBQOSA-N 158101 US9024044, 29::US9227949, 29 Enteropeptidase Homo sapiens 1.18 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158101&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044944 254815295 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300382 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCC(O)=O InChI=1S/C23H28FN3O5S/c1-3-23(4-2,22(31)27-11-5-6-19(28)29)13-15-8-10-18(33-15)21(30)32-17-9-7-14(20(25)26)12-16(17)24/h7-10,12H,3-6,11,13H2,1-2H3,(H3,25,26)(H,27,31)(H,28,29) HTXAFJRASQGRGV-UHFFFAOYSA-N 158102 US9024044, 30::US9227949, 30 Enteropeptidase Homo sapiens 0.94 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158102&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044945 254815296 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300383 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) QWJBPYHICUEKBK-UHFFFAOYSA-N 158103 US9024044, 31::US9227949, 31 Enteropeptidase Homo sapiens 1.08 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158103&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044946 254815297 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300384 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccc(c1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-5-3-4-14(10-15)21(29)30)12-16-7-9-19(34-16)22(31)33-18-8-6-13(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) GITALEQGUYRJGX-UHFFFAOYSA-N 158104 US9024044, 32::US9227949, 32 Enteropeptidase Homo sapiens 1.43 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158104&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044947 254815298 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300385 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC[C@H](C1)C(O)=O InChI=1S/C22H24FN3O5S/c1-22(2,21(30)26-8-7-13(11-26)19(27)28)10-14-4-6-17(32-14)20(29)31-16-5-3-12(18(24)25)9-15(16)23/h3-6,9,13H,7-8,10-11H2,1-2H3,(H3,24,25)(H,27,28)/t13-/m1/s1 XAKJOMCOYRMPIW-CYBMUJFWSA-N 158105 US9024044, 33::US9227949, 33 Enteropeptidase Homo sapiens 1.02 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158105&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700067 254815299 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300386 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H]1COC(=O)C1 InChI=1S/C23H26FN3O5S/c1-3-23(4-2,22(30)27-14-10-19(28)31-12-14)11-15-6-8-18(33-15)21(29)32-17-7-5-13(20(25)26)9-16(17)24/h5-9,14H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,30)/t14-/m0/s1 BASUFRLNFQJYSV-AWEZNQCLSA-N 158106 US9024044, 34::US9227949, 34 Enteropeptidase Homo sapiens 2.56 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158106&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044948 254815300 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300387 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 YGHKECGTVWVLDI-FQEVSTJZSA-N 158107 US9024044, 35::US9227949, 35::US9655879, 35 Enteropeptidase Homo sapiens 2.56 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158107&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044949 254815301 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300388 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 YGHKECGTVWVLDI-HXUWFJFHSA-N 158108 US9024044, 36::US9227949, 36::US9655879, 36 Enteropeptidase Homo sapiens 4.7 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158108&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044950 254815302 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300389 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 LFNPOEKMAAWLGP-FQEVSTJZSA-N 158109 US9024044, 37::US9227949, 37::US9655879, 37 Enteropeptidase Homo sapiens 0.96 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158109&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044951 254815303 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300390 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 LFNPOEKMAAWLGP-HXUWFJFHSA-N 158110 US9024044, 38::US9227949, 38::US9655879, 38 Enteropeptidase Homo sapiens 0.97 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158110&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044952 254815304 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300391 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccnc1 InChI=1S/C22H21FN4O3S/c1-22(2,21(29)27-14-4-3-9-26-12-14)11-15-6-8-18(31-15)20(28)30-17-7-5-13(19(24)25)10-16(17)23/h3-10,12H,11H2,1-2H3,(H3,24,25)(H,27,29) GNBPVACYKKHTJB-UHFFFAOYSA-N 158111 US9024044, 39::US9227949, 39::US9655879, 39 Enteropeptidase Homo sapiens 7.56 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158111&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044953 254815305 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300392 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc[nH]c1=O InChI=1S/C22H21FN4O4S/c1-22(2,21(30)27-15-4-3-9-26-19(15)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23/h3-10H,11H2,1-2H3,(H3,24,25)(H,26,28)(H,27,30) HKARKNAVVKQMPE-UHFFFAOYSA-N 158112 US9024044, 40::US9227949, 40::US9655879, 40 Enteropeptidase Homo sapiens 6.66 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158112&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044954 254815306 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300393 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1CC(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27-9-3-4-14(27)11-19(28)29)12-15-6-8-18(33-15)21(30)32-17-7-5-13(20(25)26)10-16(17)24/h5-8,10,14H,3-4,9,11-12H2,1-2H3,(H3,25,26)(H,28,29)/t14-/m0/s1 GSRMMLAYSLEKIF-AWEZNQCLSA-N 158113 US9024044, 41::US9227949, 41 Enteropeptidase Homo sapiens 1.58 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158113&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700068 254815307 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300394 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C24H29FN4O6S/c1-3-24(4-2,23(34)29-16(21(31)32)7-10-19(26)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(27)28)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H2,26,30)(H3,27,28)(H,29,34)(H,31,32)/t16-/m0/s1 VSKNKWMUXQDPKJ-INIZCTEOSA-N 158114 US9024044, 42::US9227949, 42::US9655879, 42 Enteropeptidase Homo sapiens 1.69 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158114&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044955 254815308 C02716 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300395 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/m1/s1 MRDGTXNCJIRKAP-MRXNPFEDSA-N 158115 US9024044, 43::US9227949, 43 Enteropeptidase Homo sapiens 0.42 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158115&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044956 254815309 C06379 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300396 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C23H27FN4O6S/c1-3-23(4-2,22(33)28-15(20(30)31)10-18(25)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(26)27)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H2,25,29)(H3,26,27)(H,28,33)(H,30,31)/t15-/m0/s1 LJIGJWYAZLPIMX-HNNXBMFYSA-N 158116 US9024044, 44::US9227949, 44 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158116&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700070 254815310 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300397 COc1ccc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cn1 InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-14-5-9-19(31-3)27-12-14)11-15-6-8-18(33-15)21(29)32-17-7-4-13(20(25)26)10-16(17)24/h4-10,12H,11H2,1-3H3,(H3,25,26)(H,28,30) GGORVCBBPWZASH-UHFFFAOYSA-N 158117 US9024044, 45::US9227949, 45::US9655879, 45 Enteropeptidase Homo sapiens 4.13 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158117&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044957 254815311 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300398 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(F)(F)C1 InChI=1S/C20H20F3N3O3S/c1-19(2,18(28)26-9-20(22,23)10-26)8-12-4-6-15(30-12)17(27)29-14-5-3-11(16(24)25)7-13(14)21/h3-7H,8-10H2,1-2H3,(H3,24,25) MBNRUFIEUAXHGI-UHFFFAOYSA-N 158118 US9024044, 46::US9227949, 46::US9655879, 46 Enteropeptidase Homo sapiens 5.27 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158118&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044958 254815312 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300399 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI=1S/C24H22FN3O6S/c1-24(2,23(33)28-13-4-6-17(29)15(10-13)21(30)31)11-14-5-8-19(35-14)22(32)34-18-7-3-12(20(26)27)9-16(18)25/h3-10,29H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) SLSLVLFFHMCGMN-UHFFFAOYSA-N 158119 US9024044, 47::US9227949, 47 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158119&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700146 254815313 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300400 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-18-8-5-16(6-9-18)13-23(32)33)15-19-10-12-22(37-19)25(34)36-21-11-7-17(24(29)30)14-20(21)28/h5-12,14H,3-4,13,15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) FMQUCBATRXHMPW-UHFFFAOYSA-N 158120 US9024044, 48::US9227949, 48 Enteropeptidase Homo sapiens 2.41 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158120&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044959 254815314 C03768 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300401 CCC(C)[C@@H](CC(O)=O)NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C26H34FN3O5S/c1-5-15(4)19(13-22(31)32)30-25(34)26(6-2,7-3)14-17-9-11-21(36-17)24(33)35-20-10-8-16(23(28)29)12-18(20)27/h8-12,15,19H,5-7,13-14H2,1-4H3,(H3,28,29)(H,30,34)(H,31,32)/t15?,19-/m1/s1 VSTCGGYHPBZFEF-XCWJXAQQSA-N 158121 US9024044, 49::US9227949, 49 Enteropeptidase Homo sapiens 3.26 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158121&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044960 254815315 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300402 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCc2ccc(cc2C1)C(O)=O InChI=1S/C27H26FN3O5S/c1-27(2,26(35)31-10-9-15-3-4-17(24(32)33)11-18(15)14-31)13-19-6-8-22(37-19)25(34)36-21-7-5-16(23(29)30)12-20(21)28/h3-8,11-12H,9-10,13-14H2,1-2H3,(H3,29,30)(H,32,33) VUDQLRYFBDWFRC-UHFFFAOYSA-N 158122 US9024044, 50::US9227949, 50::US9655879, 50 Enteropeptidase Homo sapiens 3.46 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158122&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044961 254815316 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300403 COc1ncccc1NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-16-5-4-10-27-20(16)31-3)12-14-7-9-18(33-14)21(29)32-17-8-6-13(19(25)26)11-15(17)24/h4-11H,12H2,1-3H3,(H3,25,26)(H,28,30) VQICKBIEIBEKAP-UHFFFAOYSA-N 158123 US9024044, 51::US9227949, 51::US9655879, 51 Enteropeptidase Homo sapiens 3.75 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158123&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044962 254815317 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300404 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC[C@H](N)C(O)=O InChI=1S/C24H31FN4O5S/c1-3-24(4-2,23(33)29-11-5-6-17(26)21(30)31)13-15-8-10-19(35-15)22(32)34-18-9-7-14(20(27)28)12-16(18)25/h7-10,12,17H,3-6,11,13,26H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t17-/m0/s1 MZDLVWCRTMDQMT-KRWDZBQOSA-N 158124 US9024044, 52::US9227949, 52 Enteropeptidase Homo sapiens 5.53 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158124&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044963 254815318 C02858 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300405 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1ccc(cc1)C(O)=O InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-15-16-5-7-17(8-6-16)24(32)33)14-19-10-12-22(37-19)25(34)36-21-11-9-18(23(29)30)13-20(21)28/h5-13H,3-4,14-15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) UCVYMBGYTGPRBW-UHFFFAOYSA-N 158125 US9024044, 53::US9227949, 53 Enteropeptidase Homo sapiens 2.69 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158125&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044964 254815319 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300406 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@@H]1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26)/t13-,24?/m1/s1 NWTMDNVGALXRNH-SGZRZGDHSA-N 158126 US9024044, 54::US9227949, 54 Enteropeptidase Homo sapiens 1.76 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158126&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044965 254815320 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300407 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(F)nc1 InChI=1S/C22H20F2N4O3S/c1-22(2,21(30)28-13-4-8-18(24)27-11-13)10-14-5-7-17(32-14)20(29)31-16-6-3-12(19(25)26)9-15(16)23/h3-9,11H,10H2,1-2H3,(H3,25,26)(H,28,30) HPQNZKOUBYGLOW-UHFFFAOYSA-N 158127 US9024044, 55::US9227949, 55::US9655879, 55 Enteropeptidase Homo sapiens 2.51 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158127&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044966 254815321 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300408 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C22H24FN3O5S/c1-21(2,19(28)26-22(20(29)30)8-3-9-22)11-13-5-7-16(32-13)18(27)31-15-6-4-12(17(24)25)10-14(15)23/h4-7,10H,3,8-9,11H2,1-2H3,(H3,24,25)(H,26,28)(H,29,30) YRTBCUYEEWAYIN-UHFFFAOYSA-N 158128 US9024044, 56::US9227949, 56 Enteropeptidase Homo sapiens 0.51 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158128&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700147 254815322 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300409 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C21H22FN3O5S/c1-20(2,18(27)25-21(7-8-21)19(28)29)10-12-4-6-15(31-12)17(26)30-14-5-3-11(16(23)24)9-13(14)22/h3-6,9H,7-8,10H2,1-2H3,(H3,23,24)(H,25,27)(H,28,29) NQWKELPUBUTTAS-UHFFFAOYSA-N 158129 US9024044, 57::US9227949, 57 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158129&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044967 254815323 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300410 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(CCC(O)=O)(CCC(O)=O)CCC(O)=O InChI=1S/C27H32FN3O9S/c1-26(2,25(39)31-27(10-7-20(32)33,11-8-21(34)35)12-9-22(36)37)14-16-4-6-19(41-16)24(38)40-18-5-3-15(23(29)30)13-17(18)28/h3-6,13H,7-12,14H2,1-2H3,(H3,29,30)(H,31,39)(H,32,33)(H,34,35)(H,36,37) ARRGOUAMPKSURR-UHFFFAOYSA-N 158130 US9024044, 58::US9227949, 58::US9655879, 58 Enteropeptidase Homo sapiens 0.71 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158130&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700148 254815324 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300411 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) WDYKMWXZCPOZKO-UHFFFAOYSA-N 158131 US9024044, 59::US9227949, 59::US9655879, 59 Enteropeptidase Homo sapiens 0.31 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158131&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700149 254815325 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300412 COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cc(c1)C(=O)OC InChI=1S/C27H26FN3O7S/c1-27(2,26(35)31-17-10-15(23(32)36-3)9-16(11-17)24(33)37-4)13-18-6-8-21(39-18)25(34)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,13H2,1-4H3,(H3,29,30)(H,31,35) UHWHRMYFHIAVQB-UHFFFAOYSA-N 158132 US9024044, 60::US9227949, 60::US9655879, 60 Enteropeptidase Homo sapiens 1.22 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158132&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044968 254815326 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300413 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H]1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26)/t13-,24?/m0/s1 NWTMDNVGALXRNH-LNHXHEARSA-N 158133 US9024044, 61::US9227949, 61::US9655879, 61 Enteropeptidase Homo sapiens 1.13 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158133&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044969 254815327 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300414 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCC(O)=O InChI=1S/C24H30FN3O5S/c1-3-24(4-2,23(32)28-12-6-5-7-20(29)30)14-16-9-11-19(34-16)22(31)33-18-10-8-15(21(26)27)13-17(18)25/h8-11,13H,3-7,12,14H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) JBHHRVQRHSBNTN-UHFFFAOYSA-N 158134 US9024044, 62::US9227949, 62 Enteropeptidase Homo sapiens 0.98 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158134&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044970 254815328 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300415 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC#N InChI=1S/C20H21FN4O3S/c1-20(2,19(27)25-9-3-8-22)11-13-5-7-16(29-13)18(26)28-15-6-4-12(17(23)24)10-14(15)21/h4-7,10H,3,9,11H2,1-2H3,(H3,23,24)(H,25,27) NCNMXHNAIQAZJK-UHFFFAOYSA-N 158135 US9024044, 63::US9227949, 63 Enteropeptidase Homo sapiens 2.9 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158135&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044971 254815329 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300416 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCc1nnn[nH]1 InChI=1S/C20H22FN7O3S/c1-20(2,19(30)24-8-7-16-25-27-28-26-16)10-12-4-6-15(32-12)18(29)31-14-5-3-11(17(22)23)9-13(14)21/h3-6,9H,7-8,10H2,1-2H3,(H3,22,23)(H,24,30)(H,25,26,27,28) ASUXORKUDJSWOW-UHFFFAOYSA-N 158136 US9024044, 64::US9227949, 64 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158136&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700150 254815330 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300417 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C19H20FN7O3S/c1-19(2,18(29)23-9-15-24-26-27-25-15)8-11-4-6-14(31-11)17(28)30-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,29)(H,24,25,26,27) UQNVEJVKVQTREV-UHFFFAOYSA-N 158137 BDBM308529::US9024044, 65::US9227949, 65 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158137&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700231 254815331 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300418 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C27H26FN3O7S/c1-3-27(4-2,26(37)31-17-10-15(23(32)33)9-16(11-17)24(34)35)13-18-6-8-21(39-18)25(36)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,3-4,13H2,1-2H3,(H3,29,30)(H,31,37)(H,32,33)(H,34,35) NEIQENFRFQTURN-UHFFFAOYSA-N 158138 US9024044, 66::US9227949, 66::US9655879, 66 Enteropeptidase Homo sapiens 0.71 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158138&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700232 254815332 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300419 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(=O)OC)C(O)=O InChI=1S/C28H28FN3O7S/c1-4-28(5-2,27(37)32-18-11-16(24(33)34)10-17(12-18)25(35)38-3)14-19-7-9-22(40-19)26(36)39-21-8-6-15(23(30)31)13-20(21)29/h6-13H,4-5,14H2,1-3H3,(H3,30,31)(H,32,37)(H,33,34) OXNWGHGTGKAZFK-UHFFFAOYSA-N 158139 US9024044, 67::US9227949, 67::US9655879, 67 Enteropeptidase Homo sapiens 3.73 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158139&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044972 254815333 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300420 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) PPLWQAMMKNZODE-UHFFFAOYSA-N 158140 US9024044, 68::US9227949, 68::US9655879, 68 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158140&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700233 254815334 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300421 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1 XXVYMALEOOTBKD-HXUWFJFHSA-N 158141 US9024044, 69::US9227949, 69::US9655879, 69 Enteropeptidase Homo sapiens 0.72 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158141&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700234 254815335 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300422 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t13-,15+ QEZAEHZBTXJQOF-OTVXOJSOSA-N 158142 US9024044, 70::US9227949, 70 Enteropeptidase Homo sapiens 1.11 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158142&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044973 254815336 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300423 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCCC(O)=O InChI=1S/C25H32FN3O5S/c1-3-25(4-2,24(33)29-13-7-5-6-8-21(30)31)15-17-10-12-20(35-17)23(32)34-19-11-9-16(22(27)28)14-18(19)26/h9-12,14H,3-8,13,15H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31) ACEUOZVTHUQNKZ-UHFFFAOYSA-N 158143 US9024044, 71::US9227949, 71 Enteropeptidase Homo sapiens 4.97 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158143&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044974 254815337 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300424 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(C1)C(O)=O InChI=1S/C21H22FN3O5S/c1-21(2,20(29)25-9-12(10-25)18(26)27)8-13-4-6-16(31-13)19(28)30-15-5-3-11(17(23)24)7-14(15)22/h3-7,12H,8-10H2,1-2H3,(H3,23,24)(H,26,27) PRXOELBXTGUDLM-UHFFFAOYSA-N 158144 US9024044, 72::US9227949, 72::US9655879, 72 Enteropeptidase Homo sapiens 0.63 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158144&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700235 254815338 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300425 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccccc1C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-17-6-4-3-5-15(17)21(29)30)12-14-8-10-19(34-14)22(31)33-18-9-7-13(20(26)27)11-16(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) NRLONGNAKYXRSF-UHFFFAOYSA-N 158145 US9024044, 73::US9227949, 73 Enteropeptidase Homo sapiens 2.41 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158145&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044975 254815339 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300426 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) WBRGSXXRFXKGIY-UHFFFAOYSA-N 158146 US9024044, 74::US9227949, 74::US9655879, 74 Enteropeptidase Homo sapiens 0.58 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158146&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 102594267 254815340 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300427 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) LTAGTBZSDPMYPZ-UHFFFAOYSA-N 158147 US9024044, 75::US9227949, 75::US9655879, 75 Enteropeptidase Homo sapiens 0.39 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158147&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044976 254815341 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300428 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC1CC1)CC(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27(12-19(28)29)11-13-3-4-13)10-15-6-8-18(33-15)21(30)32-17-7-5-14(20(25)26)9-16(17)24/h5-9,13H,3-4,10-12H2,1-2H3,(H3,25,26)(H,28,29) QSMCGKUCUJMHFH-UHFFFAOYSA-N 158148 US9024044, 76::US9227949, 76 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158148&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044977 254815342 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300429 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(=O)NCC(O)=O InChI=1S/C23H27FN4O6S/c1-3-23(4-2,22(33)28-11-18(29)27-12-19(30)31)10-14-6-8-17(35-14)21(32)34-16-7-5-13(20(25)26)9-15(16)24/h5-9H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,29)(H,28,33)(H,30,31) YCIHRVPQPIJYOG-UHFFFAOYSA-N 158149 BDBM308541::US9024044, 77::US9227949, 77 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158149&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044978 254815343 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300430 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t13-,15- QEZAEHZBTXJQOF-CTYIDZIISA-N 158150 US9024044, 78::US9227949, 78 Enteropeptidase Homo sapiens 1.53 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158150&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044973 254815344 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300431 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-3-22(4-2,20(29)27-23(9-10-23)21(30)31)12-14-6-8-17(33-14)19(28)32-16-7-5-13(18(25)26)11-15(16)24/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,25,26)(H,27,29)(H,30,31) FJLPBYYWEBALPV-UHFFFAOYSA-N 158151 US9024044, 79::US9227949, 79 Enteropeptidase Homo sapiens 1.12 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158151&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044979 254815345 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300432 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-3-23(4-2,21(30)28-24(22(31)32)10-5-11-24)13-15-7-9-18(34-15)20(29)33-17-8-6-14(19(26)27)12-16(17)25/h6-9,12H,3-5,10-11,13H2,1-2H3,(H3,26,27)(H,28,30)(H,31,32) IZBCXOUJPXKGHT-UHFFFAOYSA-N 158152 US9024044, 80::US9227949, 80 Enteropeptidase Homo sapiens 1.33 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158152&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044980 254815346 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 300433 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C21H24FN7O3S/c1-3-21(4-2,20(31)25-11-17-26-28-29-27-17)10-13-6-8-16(33-13)19(30)32-15-7-5-12(18(23)24)9-14(15)22/h5-9H,3-4,10-11H2,1-2H3,(H3,23,24)(H,25,31)(H,26,27,28,29) LJLCZQKLQRISET-UHFFFAOYSA-N 158153 BDBM308545::US9024044, 81::US9227949, 81 Enteropeptidase Homo sapiens 1.2 8 US Patent 10.7270/Q2F47MVB aid1801213 US9024044 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158153&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90070125 254815347 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355525 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/m0/s1 CHAXFLSDNLDWPP-AWEZNQCLSA-N 158073 US9024044, 1::US9227949, 1::US9655879, 1 Enteropeptidase Homo sapiens 0.14 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158073&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699917 254815267 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355526 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C23H24FN3O7S/c24-14-9-12(19(25)26)3-5-16(14)34-21(32)17-6-4-13(35-17)11-23(7-1-2-8-23)22(33)27-15(20(30)31)10-18(28)29/h3-6,9,15H,1-2,7-8,10-11H2,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m0/s1 HXDKJHJAMFQXBA-HNNXBMFYSA-N 158074 US9024044, 2::US9227949, 2::US9655879, 2 Enteropeptidase Homo sapiens 0.73 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158074&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90019132 254815268 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355527 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O InChI=1S/C19H20FN3O5S/c1-19(2,18(27)23-9-15(24)25)8-11-4-6-14(29-11)17(26)28-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,27)(H,24,25) FBFZNZYSXBOYCU-UHFFFAOYSA-N 158075 US9024044, 3::US9227949, 3 Enteropeptidase Homo sapiens 0.29 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158075&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699918 254815269 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355528 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C20H22FN3O6S/c1-20(2,19(29)24-13(9-25)17(26)27)8-11-4-6-15(31-11)18(28)30-14-5-3-10(16(22)23)7-12(14)21/h3-7,13,25H,8-9H2,1-2H3,(H3,22,23)(H,24,29)(H,26,27)/t13-/m0/s1 PGOXWLZRNRRTHV-ZDUSSCGKSA-N 158076 US9024044, 4::US9227949, 4::US9655879, 4 Enteropeptidase Homo sapiens 0.46 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158076&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699919 254815270 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355529 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28) XYNSVADDWDUDBJ-UHFFFAOYSA-N 158077 US9024044, 5::US9227949, 5::US9655879, 5 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158077&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699920 254815271 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355530 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(C)(C)C(O)=O InChI=1S/C21H24FN3O5S/c1-20(2,18(27)25-21(3,4)19(28)29)10-12-6-8-15(31-12)17(26)30-14-7-5-11(16(23)24)9-13(14)22/h5-9H,10H2,1-4H3,(H3,23,24)(H,25,27)(H,28,29) CXAAAVDPZVTHHD-UHFFFAOYSA-N 158078 US9024044, 6::US9227949, 6::US9655879, 6 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158078&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699921 254815272 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355531 CN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H22FN3O5S/c1-20(2,19(28)24(3)10-16(25)26)9-12-5-7-15(30-12)18(27)29-14-6-4-11(17(22)23)8-13(14)21/h4-8H,9-10H2,1-3H3,(H3,22,23)(H,25,26) LWAVAXQFRSKGMV-UHFFFAOYSA-N 158079 US9024044, 7::US9227949, 7::US9655879, 7 Enteropeptidase Homo sapiens 0.41 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158079&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044933 254815273 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355532 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C22H24FN3O5S/c1-22(2,21(30)26-9-3-4-15(26)19(27)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23/h5-8,10,15H,3-4,9,11H2,1-2H3,(H3,24,25)(H,27,28)/t15-/m0/s1 BBMBOQSWYMFNGF-HNNXBMFYSA-N 158080 US9024044, 8::US9227949, 8 Enteropeptidase Homo sapiens 0.87 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158080&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044934 254815274 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355533 CC(C)[C@H](NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C22H26FN3O5S/c1-11(2)17(19(27)28)26-21(30)22(3,4)10-13-6-8-16(32-13)20(29)31-15-7-5-12(18(24)25)9-14(15)23/h5-9,11,17H,10H2,1-4H3,(H3,24,25)(H,26,30)(H,27,28)/t17-/m0/s1 WDNTXANUISNDIT-KRWDZBQOSA-N 158081 US9024044, 9::US9227949, 9 Enteropeptidase Homo sapiens 0.79 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158081&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018773 254815275 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355534 CCCN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H26FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h5-8,10H,4,9,11-12H2,1-3H3,(H3,24,25)(H,27,28) VCKIEANVSOSDBH-UHFFFAOYSA-N 158082 US9024044, 10::US9227949, 10 Enteropeptidase Homo sapiens 0.49 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158082&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699992 254815276 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355535 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C22H26FN3O6S/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29)/t15-/m0/s1 LFSLIAZOFSRRDB-HNNXBMFYSA-N 158083 US9024044, 11::US9227949, 11 Enteropeptidase Homo sapiens 0.41 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158083&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699993 254815277 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355536 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CO)C(O)=O InChI=1S/C22H26FN3O6S/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29)/t15-/m1/s1 LFSLIAZOFSRRDB-OAHLLOKOSA-N 158084 US9024044, 12::US9227949, 12 Enteropeptidase Homo sapiens 0.94 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158084&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044935 254815278 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355537 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C24H30FN3O5S/c1-5-24(6-2,23(32)28-19(13(3)4)21(29)30)12-15-8-10-18(34-15)22(31)33-17-9-7-14(20(26)27)11-16(17)25/h7-11,13,19H,5-6,12H2,1-4H3,(H3,26,27)(H,28,32)(H,29,30)/t19-/m0/s1 QCKHQIYRKNPRBR-IBGZPJMESA-N 158085 US9024044, 13::US9227949, 13 Enteropeptidase Homo sapiens 1.56 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158085&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699994 254815279 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355538 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC(O)=O InChI=1S/C22H26FN3O5S/c1-3-22(4-2,21(30)26-10-9-18(27)28)12-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)11-15(16)23/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,24,25)(H,26,30)(H,27,28) RMZDNEFSCYWLFZ-UHFFFAOYSA-N 158086 US9024044, 14::US9227949, 14 Enteropeptidase Homo sapiens 0.99 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158086&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699995 254815280 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355539 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)O)C(O)=O InChI=1S/C23H28FN3O6S/c1-4-23(5-2,22(32)27-18(12(3)28)20(29)30)11-14-7-9-17(34-14)21(31)33-16-8-6-13(19(25)26)10-15(16)24/h6-10,12,18,28H,4-5,11H2,1-3H3,(H3,25,26)(H,27,32)(H,29,30)/t12?,18-/m0/s1 JKNBTSMKSSJRDC-ZJFPTPTDSA-N 158087 US9024044, 15::US9227949, 15 Enteropeptidase Homo sapiens 0.84 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158087&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044936 254815281 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355540 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C28H30FN3O5S/c1-3-28(4-2,27(36)32-21(25(33)34)14-17-8-6-5-7-9-17)16-19-11-13-23(38-19)26(35)37-22-12-10-18(24(30)31)15-20(22)29/h5-13,15,21H,3-4,14,16H2,1-2H3,(H3,30,31)(H,32,36)(H,33,34)/t21-/m0/s1 PGPODLSJZFFJCS-NRFANRHFSA-N 158088 US9024044, 16::US9227949, 16 Enteropeptidase Homo sapiens 1.10 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158088&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044937 254815282 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355541 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C24H28FN3O5S/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30)/t17-/m0/s1 PJQIIQDUTSQWIS-KRWDZBQOSA-N 158089 US9024044, 17::US9227949, 17 Enteropeptidase Homo sapiens 1.69 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158089&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044938 254815283 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355542 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C19H21FN2O4S/c1-3-19(4-2,18(24)25)10-12-6-8-15(27-12)17(23)26-14-7-5-11(16(21)22)9-13(14)20/h5-9H,3-4,10H2,1-2H3,(H3,21,22)(H,24,25) NVBTXQNZNQVUIV-UHFFFAOYSA-N 158090 US9024044, 18::US9227949, 18::US9655879, 18 Enteropeptidase Homo sapiens 1.24 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158090&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699996 254815284 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355543 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m0/s1 IBHPUOCNUKPTBM-HNNXBMFYSA-N 158091 US9024044, 19::US9227949, 19 Enteropeptidase Homo sapiens 0.33 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158091&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72543744 254815285 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355544 CCCN(CC(O)=O)C(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C24H30FN3O5S/c1-4-11-28(14-20(29)30)23(32)24(5-2,6-3)13-16-8-10-19(34-16)22(31)33-18-9-7-15(21(26)27)12-17(18)25/h7-10,12H,4-6,11,13-14H2,1-3H3,(H3,26,27)(H,29,30) QRSQMHVQHCFHOA-UHFFFAOYSA-N 158092 US9024044, 20::US9227949, 20 Enteropeptidase Homo sapiens 2.61 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158092&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044939 254815286 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355545 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(C)CC(O)=O InChI=1S/C22H26FN3O5S/c1-4-22(5-2,21(30)26(3)12-18(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(19(24)25)10-15(16)23/h6-10H,4-5,11-12H2,1-3H3,(H3,24,25)(H,27,28) JGFFFJLERKVFRG-UHFFFAOYSA-N 158093 US9024044, 21::US9227949, 21 Enteropeptidase Homo sapiens 0.88 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158093&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018822 254815287 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355546 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@@H]1C(O)=O InChI=1S/C24H28FN3O5S/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30)/t17-/m1/s1 PJQIIQDUTSQWIS-QGZVFWFLSA-N 158094 US9024044, 22::US9227949, 22 Enteropeptidase Homo sapiens 1.00 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158094&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044940 254815288 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355547 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CCS(O)(=O)=O)CC=C InChI=1S/C22H26FN3O6S2/c1-4-9-26(10-11-34(29,30)31)21(28)22(2,3)13-15-6-8-18(33-15)20(27)32-17-7-5-14(19(24)25)12-16(17)23/h4-8,12H,1,9-11,13H2,2-3H3,(H3,24,25)(H,29,30,31) DULSYBFZNKGICA-UHFFFAOYSA-N 158095 US9024044, 23::US9227949, 23::US9655879, 23 Enteropeptidase Homo sapiens 1.81 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158095&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90017966 254815289 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355548 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/m0/s1 MRDGTXNCJIRKAP-INIZCTEOSA-N 158096 US9024044, 24::US9227949, 24 Enteropeptidase Homo sapiens 0.27 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158096&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700069 254815290 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355549 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m1/s1 IBHPUOCNUKPTBM-OAHLLOKOSA-N 158097 US9024044, 25::US9227949, 25 Enteropeptidase Homo sapiens 0.26 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158097&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044941 254815291 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355550 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27-9-7-13(8-10-27)20(28)29)12-15-4-6-18(33-15)21(30)32-17-5-3-14(19(25)26)11-16(17)24/h3-6,11,13H,7-10,12H2,1-2H3,(H3,25,26)(H,28,29) JKGGZKLIDGJKFW-UHFFFAOYSA-N 158098 US9024044, 26::US9227949, 26 Enteropeptidase Homo sapiens 1.33 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158098&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044942 254815292 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355551 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C)C(O)=O InChI=1S/C22H26FN3O5S/c1-4-22(5-2,21(30)26-12(3)19(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(18(24)25)10-15(16)23/h6-10,12H,4-5,11H2,1-3H3,(H3,24,25)(H,26,30)(H,27,28)/t12-/m0/s1 WHADCIUXAGXHJQ-LBPRGKRZSA-N 158099 US9024044, 27::US9227949, 27 Enteropeptidase Homo sapiens 0.73 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158099&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044943 254815293 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355552 CC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C23H28FN3O5S/c1-4-16(20(28)29)27-22(31)23(5-2,6-3)12-14-8-10-18(33-14)21(30)32-17-9-7-13(19(25)26)11-15(17)24/h7-11,16H,4-6,12H2,1-3H3,(H3,25,26)(H,27,31)(H,28,29)/t16-/m0/s1 WSPUTIGUOKODRG-INIZCTEOSA-N 158100 US9024044, 28::US9227949, 28 Enteropeptidase Homo sapiens 0.65 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158100&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700066 254815294 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355553 CCC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C24H30FN3O5S/c1-4-7-17(21(29)30)28-23(32)24(5-2,6-3)13-15-9-11-19(34-15)22(31)33-18-10-8-14(20(26)27)12-16(18)25/h8-12,17H,4-7,13H2,1-3H3,(H3,26,27)(H,28,32)(H,29,30)/t17-/m0/s1 AGFHBSKFKFQJEM-KRWDZBQOSA-N 158101 US9024044, 29::US9227949, 29 Enteropeptidase Homo sapiens 1.18 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158101&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044944 254815295 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355554 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCC(O)=O InChI=1S/C23H28FN3O5S/c1-3-23(4-2,22(31)27-11-5-6-19(28)29)13-15-8-10-18(33-15)21(30)32-17-9-7-14(20(25)26)12-16(17)24/h7-10,12H,3-6,11,13H2,1-2H3,(H3,25,26)(H,27,31)(H,28,29) HTXAFJRASQGRGV-UHFFFAOYSA-N 158102 US9024044, 30::US9227949, 30 Enteropeptidase Homo sapiens 0.94 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158102&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044945 254815296 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355555 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) QWJBPYHICUEKBK-UHFFFAOYSA-N 158103 US9024044, 31::US9227949, 31 Enteropeptidase Homo sapiens 1.08 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158103&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044946 254815297 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355556 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccc(c1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-5-3-4-14(10-15)21(29)30)12-16-7-9-19(34-16)22(31)33-18-8-6-13(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) GITALEQGUYRJGX-UHFFFAOYSA-N 158104 US9024044, 32::US9227949, 32 Enteropeptidase Homo sapiens 1.43 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158104&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044947 254815298 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355557 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC[C@H](C1)C(O)=O InChI=1S/C22H24FN3O5S/c1-22(2,21(30)26-8-7-13(11-26)19(27)28)10-14-4-6-17(32-14)20(29)31-16-5-3-12(18(24)25)9-15(16)23/h3-6,9,13H,7-8,10-11H2,1-2H3,(H3,24,25)(H,27,28)/t13-/m1/s1 XAKJOMCOYRMPIW-CYBMUJFWSA-N 158105 US9024044, 33::US9227949, 33 Enteropeptidase Homo sapiens 1.02 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158105&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700067 254815299 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355558 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H]1COC(=O)C1 InChI=1S/C23H26FN3O5S/c1-3-23(4-2,22(30)27-14-10-19(28)31-12-14)11-15-6-8-18(33-15)21(29)32-17-7-5-13(20(25)26)9-16(17)24/h5-9,14H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,30)/t14-/m0/s1 BASUFRLNFQJYSV-AWEZNQCLSA-N 158106 US9024044, 34::US9227949, 34 Enteropeptidase Homo sapiens 2.56 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158106&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044948 254815300 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355559 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 YGHKECGTVWVLDI-FQEVSTJZSA-N 158107 US9024044, 35::US9227949, 35::US9655879, 35 Enteropeptidase Homo sapiens 2.56 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158107&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044949 254815301 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355560 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 YGHKECGTVWVLDI-HXUWFJFHSA-N 158108 US9024044, 36::US9227949, 36::US9655879, 36 Enteropeptidase Homo sapiens 4.70 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158108&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044950 254815302 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355561 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 LFNPOEKMAAWLGP-FQEVSTJZSA-N 158109 US9024044, 37::US9227949, 37::US9655879, 37 Enteropeptidase Homo sapiens 0.96 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158109&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044951 254815303 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355562 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 LFNPOEKMAAWLGP-HXUWFJFHSA-N 158110 US9024044, 38::US9227949, 38::US9655879, 38 Enteropeptidase Homo sapiens 0.97 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158110&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044952 254815304 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355563 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccnc1 InChI=1S/C22H21FN4O3S/c1-22(2,21(29)27-14-4-3-9-26-12-14)11-15-6-8-18(31-15)20(28)30-17-7-5-13(19(24)25)10-16(17)23/h3-10,12H,11H2,1-2H3,(H3,24,25)(H,27,29) GNBPVACYKKHTJB-UHFFFAOYSA-N 158111 US9024044, 39::US9227949, 39::US9655879, 39 Enteropeptidase Homo sapiens 7.56 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158111&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044953 254815305 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355564 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc[nH]c1=O InChI=1S/C22H21FN4O4S/c1-22(2,21(30)27-15-4-3-9-26-19(15)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23/h3-10H,11H2,1-2H3,(H3,24,25)(H,26,28)(H,27,30) HKARKNAVVKQMPE-UHFFFAOYSA-N 158112 US9024044, 40::US9227949, 40::US9655879, 40 Enteropeptidase Homo sapiens 6.66 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158112&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044954 254815306 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355565 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1CC(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27-9-3-4-14(27)11-19(28)29)12-15-6-8-18(33-15)21(30)32-17-7-5-13(20(25)26)10-16(17)24/h5-8,10,14H,3-4,9,11-12H2,1-2H3,(H3,25,26)(H,28,29)/t14-/m0/s1 GSRMMLAYSLEKIF-AWEZNQCLSA-N 158113 US9024044, 41::US9227949, 41 Enteropeptidase Homo sapiens 1.58 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158113&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700068 254815307 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355566 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C24H29FN4O6S/c1-3-24(4-2,23(34)29-16(21(31)32)7-10-19(26)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(27)28)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H2,26,30)(H3,27,28)(H,29,34)(H,31,32)/t16-/m0/s1 VSKNKWMUXQDPKJ-INIZCTEOSA-N 158114 US9024044, 42::US9227949, 42::US9655879, 42 Enteropeptidase Homo sapiens 1.69 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158114&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044955 254815308 C02716 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355567 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/m1/s1 MRDGTXNCJIRKAP-MRXNPFEDSA-N 158115 US9024044, 43::US9227949, 43 Enteropeptidase Homo sapiens 0.42 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158115&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044956 254815309 C06379 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355568 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C23H27FN4O6S/c1-3-23(4-2,22(33)28-15(20(30)31)10-18(25)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(26)27)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H2,25,29)(H3,26,27)(H,28,33)(H,30,31)/t15-/m0/s1 LJIGJWYAZLPIMX-HNNXBMFYSA-N 158116 US9024044, 44::US9227949, 44 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158116&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700070 254815310 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355569 COc1ccc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cn1 InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-14-5-9-19(31-3)27-12-14)11-15-6-8-18(33-15)21(29)32-17-7-4-13(20(25)26)10-16(17)24/h4-10,12H,11H2,1-3H3,(H3,25,26)(H,28,30) GGORVCBBPWZASH-UHFFFAOYSA-N 158117 US9024044, 45::US9227949, 45::US9655879, 45 Enteropeptidase Homo sapiens 4.13 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158117&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044957 254815311 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355570 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(F)(F)C1 InChI=1S/C20H20F3N3O3S/c1-19(2,18(28)26-9-20(22,23)10-26)8-12-4-6-15(30-12)17(27)29-14-5-3-11(16(24)25)7-13(14)21/h3-7H,8-10H2,1-2H3,(H3,24,25) MBNRUFIEUAXHGI-UHFFFAOYSA-N 158118 US9024044, 46::US9227949, 46::US9655879, 46 Enteropeptidase Homo sapiens 5.27 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158118&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044958 254815312 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355571 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI=1S/C24H22FN3O6S/c1-24(2,23(33)28-13-4-6-17(29)15(10-13)21(30)31)11-14-5-8-19(35-14)22(32)34-18-7-3-12(20(26)27)9-16(18)25/h3-10,29H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) SLSLVLFFHMCGMN-UHFFFAOYSA-N 158119 US9024044, 47::US9227949, 47 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158119&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700146 254815313 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355572 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-18-8-5-16(6-9-18)13-23(32)33)15-19-10-12-22(37-19)25(34)36-21-11-7-17(24(29)30)14-20(21)28/h5-12,14H,3-4,13,15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) FMQUCBATRXHMPW-UHFFFAOYSA-N 158120 US9024044, 48::US9227949, 48 Enteropeptidase Homo sapiens 2.41 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158120&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044959 254815314 C03768 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355573 CCC(C)[C@@H](CC(O)=O)NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C26H34FN3O5S/c1-5-15(4)19(13-22(31)32)30-25(34)26(6-2,7-3)14-17-9-11-21(36-17)24(33)35-20-10-8-16(23(28)29)12-18(20)27/h8-12,15,19H,5-7,13-14H2,1-4H3,(H3,28,29)(H,30,34)(H,31,32)/t15?,19-/m1/s1 VSTCGGYHPBZFEF-XCWJXAQQSA-N 158121 US9024044, 49::US9227949, 49 Enteropeptidase Homo sapiens 3.26 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158121&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044960 254815315 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355574 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCc2ccc(cc2C1)C(O)=O InChI=1S/C27H26FN3O5S/c1-27(2,26(35)31-10-9-15-3-4-17(24(32)33)11-18(15)14-31)13-19-6-8-22(37-19)25(34)36-21-7-5-16(23(29)30)12-20(21)28/h3-8,11-12H,9-10,13-14H2,1-2H3,(H3,29,30)(H,32,33) VUDQLRYFBDWFRC-UHFFFAOYSA-N 158122 US9024044, 50::US9227949, 50::US9655879, 50 Enteropeptidase Homo sapiens 3.46 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158122&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044961 254815316 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355575 COc1ncccc1NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-16-5-4-10-27-20(16)31-3)12-14-7-9-18(33-14)21(29)32-17-8-6-13(19(25)26)11-15(17)24/h4-11H,12H2,1-3H3,(H3,25,26)(H,28,30) VQICKBIEIBEKAP-UHFFFAOYSA-N 158123 US9024044, 51::US9227949, 51::US9655879, 51 Enteropeptidase Homo sapiens 3.75 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158123&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044962 254815317 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355576 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC[C@H](N)C(O)=O InChI=1S/C24H31FN4O5S/c1-3-24(4-2,23(33)29-11-5-6-17(26)21(30)31)13-15-8-10-19(35-15)22(32)34-18-9-7-14(20(27)28)12-16(18)25/h7-10,12,17H,3-6,11,13,26H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t17-/m0/s1 MZDLVWCRTMDQMT-KRWDZBQOSA-N 158124 US9024044, 52::US9227949, 52 Enteropeptidase Homo sapiens 5.53 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158124&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044963 254815318 C02858 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355577 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1ccc(cc1)C(O)=O InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-15-16-5-7-17(8-6-16)24(32)33)14-19-10-12-22(37-19)25(34)36-21-11-9-18(23(29)30)13-20(21)28/h5-13H,3-4,14-15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) UCVYMBGYTGPRBW-UHFFFAOYSA-N 158125 US9024044, 53::US9227949, 53 Enteropeptidase Homo sapiens 2.69 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158125&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044964 254815319 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355578 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@@H]1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26)/t13-,24?/m1/s1 NWTMDNVGALXRNH-SGZRZGDHSA-N 158126 US9024044, 54::US9227949, 54 Enteropeptidase Homo sapiens 1.76 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158126&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044965 254815320 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355579 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(F)nc1 InChI=1S/C22H20F2N4O3S/c1-22(2,21(30)28-13-4-8-18(24)27-11-13)10-14-5-7-17(32-14)20(29)31-16-6-3-12(19(25)26)9-15(16)23/h3-9,11H,10H2,1-2H3,(H3,25,26)(H,28,30) HPQNZKOUBYGLOW-UHFFFAOYSA-N 158127 US9024044, 55::US9227949, 55::US9655879, 55 Enteropeptidase Homo sapiens 2.51 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158127&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044966 254815321 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355580 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C22H24FN3O5S/c1-21(2,19(28)26-22(20(29)30)8-3-9-22)11-13-5-7-16(32-13)18(27)31-15-6-4-12(17(24)25)10-14(15)23/h4-7,10H,3,8-9,11H2,1-2H3,(H3,24,25)(H,26,28)(H,29,30) YRTBCUYEEWAYIN-UHFFFAOYSA-N 158128 US9024044, 56::US9227949, 56 Enteropeptidase Homo sapiens 0.51 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158128&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700147 254815322 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355581 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C21H22FN3O5S/c1-20(2,18(27)25-21(7-8-21)19(28)29)10-12-4-6-15(31-12)17(26)30-14-5-3-11(16(23)24)9-13(14)22/h3-6,9H,7-8,10H2,1-2H3,(H3,23,24)(H,25,27)(H,28,29) NQWKELPUBUTTAS-UHFFFAOYSA-N 158129 US9024044, 57::US9227949, 57 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158129&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044967 254815323 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355582 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(CCC(O)=O)(CCC(O)=O)CCC(O)=O InChI=1S/C27H32FN3O9S/c1-26(2,25(39)31-27(10-7-20(32)33,11-8-21(34)35)12-9-22(36)37)14-16-4-6-19(41-16)24(38)40-18-5-3-15(23(29)30)13-17(18)28/h3-6,13H,7-12,14H2,1-2H3,(H3,29,30)(H,31,39)(H,32,33)(H,34,35)(H,36,37) ARRGOUAMPKSURR-UHFFFAOYSA-N 158130 US9024044, 58::US9227949, 58::US9655879, 58 Enteropeptidase Homo sapiens 0.71 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158130&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700148 254815324 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355583 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) WDYKMWXZCPOZKO-UHFFFAOYSA-N 158131 US9024044, 59::US9227949, 59::US9655879, 59 Enteropeptidase Homo sapiens 0.31 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158131&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700149 254815325 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355584 COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cc(c1)C(=O)OC InChI=1S/C27H26FN3O7S/c1-27(2,26(35)31-17-10-15(23(32)36-3)9-16(11-17)24(33)37-4)13-18-6-8-21(39-18)25(34)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,13H2,1-4H3,(H3,29,30)(H,31,35) UHWHRMYFHIAVQB-UHFFFAOYSA-N 158132 US9024044, 60::US9227949, 60::US9655879, 60 Enteropeptidase Homo sapiens 1.22 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158132&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044968 254815326 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355585 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H]1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26)/t13-,24?/m0/s1 NWTMDNVGALXRNH-LNHXHEARSA-N 158133 US9024044, 61::US9227949, 61::US9655879, 61 Enteropeptidase Homo sapiens 1.13 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158133&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044969 254815327 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355586 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCC(O)=O InChI=1S/C24H30FN3O5S/c1-3-24(4-2,23(32)28-12-6-5-7-20(29)30)14-16-9-11-19(34-16)22(31)33-18-10-8-15(21(26)27)13-17(18)25/h8-11,13H,3-7,12,14H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) JBHHRVQRHSBNTN-UHFFFAOYSA-N 158134 US9024044, 62::US9227949, 62 Enteropeptidase Homo sapiens 0.98 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158134&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044970 254815328 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355587 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC#N InChI=1S/C20H21FN4O3S/c1-20(2,19(27)25-9-3-8-22)11-13-5-7-16(29-13)18(26)28-15-6-4-12(17(23)24)10-14(15)21/h4-7,10H,3,9,11H2,1-2H3,(H3,23,24)(H,25,27) NCNMXHNAIQAZJK-UHFFFAOYSA-N 158135 US9024044, 63::US9227949, 63 Enteropeptidase Homo sapiens 2.90 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158135&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044971 254815329 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355588 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCc1nnn[nH]1 InChI=1S/C20H22FN7O3S/c1-20(2,19(30)24-8-7-16-25-27-28-26-16)10-12-4-6-15(32-12)18(29)31-14-5-3-11(17(22)23)9-13(14)21/h3-6,9H,7-8,10H2,1-2H3,(H3,22,23)(H,24,30)(H,25,26,27,28) ASUXORKUDJSWOW-UHFFFAOYSA-N 158136 US9024044, 64::US9227949, 64 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158136&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700150 254815330 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355589 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C19H20FN7O3S/c1-19(2,18(29)23-9-15-24-26-27-25-15)8-11-4-6-14(31-11)17(28)30-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,29)(H,24,25,26,27) UQNVEJVKVQTREV-UHFFFAOYSA-N 158137 BDBM308529::US9024044, 65::US9227949, 65 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158137&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700231 254815331 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355590 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C27H26FN3O7S/c1-3-27(4-2,26(37)31-17-10-15(23(32)33)9-16(11-17)24(34)35)13-18-6-8-21(39-18)25(36)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,3-4,13H2,1-2H3,(H3,29,30)(H,31,37)(H,32,33)(H,34,35) NEIQENFRFQTURN-UHFFFAOYSA-N 158138 US9024044, 66::US9227949, 66::US9655879, 66 Enteropeptidase Homo sapiens 0.71 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158138&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700232 254815332 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355591 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(=O)OC)C(O)=O InChI=1S/C28H28FN3O7S/c1-4-28(5-2,27(37)32-18-11-16(24(33)34)10-17(12-18)25(35)38-3)14-19-7-9-22(40-19)26(36)39-21-8-6-15(23(30)31)13-20(21)29/h6-13H,4-5,14H2,1-3H3,(H3,30,31)(H,32,37)(H,33,34) OXNWGHGTGKAZFK-UHFFFAOYSA-N 158139 US9024044, 67::US9227949, 67::US9655879, 67 Enteropeptidase Homo sapiens 3.73 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158139&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044972 254815333 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355592 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) PPLWQAMMKNZODE-UHFFFAOYSA-N 158140 US9024044, 68::US9227949, 68::US9655879, 68 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158140&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700233 254815334 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355593 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1 XXVYMALEOOTBKD-HXUWFJFHSA-N 158141 US9024044, 69::US9227949, 69::US9655879, 69 Enteropeptidase Homo sapiens 0.72 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158141&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700234 254815335 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355594 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t13-,15+ QEZAEHZBTXJQOF-OTVXOJSOSA-N 158142 US9024044, 70::US9227949, 70 Enteropeptidase Homo sapiens 1.11 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158142&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044973 254815336 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355595 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCCC(O)=O InChI=1S/C25H32FN3O5S/c1-3-25(4-2,24(33)29-13-7-5-6-8-21(30)31)15-17-10-12-20(35-17)23(32)34-19-11-9-16(22(27)28)14-18(19)26/h9-12,14H,3-8,13,15H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31) ACEUOZVTHUQNKZ-UHFFFAOYSA-N 158143 US9024044, 71::US9227949, 71 Enteropeptidase Homo sapiens 4.97 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158143&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044974 254815337 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355596 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(C1)C(O)=O InChI=1S/C21H22FN3O5S/c1-21(2,20(29)25-9-12(10-25)18(26)27)8-13-4-6-16(31-13)19(28)30-15-5-3-11(17(23)24)7-14(15)22/h3-7,12H,8-10H2,1-2H3,(H3,23,24)(H,26,27) PRXOELBXTGUDLM-UHFFFAOYSA-N 158144 US9024044, 72::US9227949, 72::US9655879, 72 Enteropeptidase Homo sapiens 0.63 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158144&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700235 254815338 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355597 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccccc1C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-17-6-4-3-5-15(17)21(29)30)12-14-8-10-19(34-14)22(31)33-18-9-7-13(20(26)27)11-16(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) NRLONGNAKYXRSF-UHFFFAOYSA-N 158145 US9024044, 73::US9227949, 73 Enteropeptidase Homo sapiens 2.41 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158145&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044975 254815339 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355598 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) WBRGSXXRFXKGIY-UHFFFAOYSA-N 158146 US9024044, 74::US9227949, 74::US9655879, 74 Enteropeptidase Homo sapiens 0.58 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158146&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 102594267 254815340 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355599 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) LTAGTBZSDPMYPZ-UHFFFAOYSA-N 158147 US9024044, 75::US9227949, 75::US9655879, 75 Enteropeptidase Homo sapiens 0.39 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158147&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044976 254815341 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355600 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC1CC1)CC(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27(12-19(28)29)11-13-3-4-13)10-15-6-8-18(33-15)21(30)32-17-7-5-14(20(25)26)9-16(17)24/h5-9,13H,3-4,10-12H2,1-2H3,(H3,25,26)(H,28,29) QSMCGKUCUJMHFH-UHFFFAOYSA-N 158148 US9024044, 76::US9227949, 76 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158148&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044977 254815342 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355601 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(=O)NCC(O)=O InChI=1S/C23H27FN4O6S/c1-3-23(4-2,22(33)28-11-18(29)27-12-19(30)31)10-14-6-8-17(35-14)21(32)34-16-7-5-13(20(25)26)9-15(16)24/h5-9H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,29)(H,28,33)(H,30,31) YCIHRVPQPIJYOG-UHFFFAOYSA-N 158149 BDBM308541::US9024044, 77::US9227949, 77 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158149&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044978 254815343 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355602 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t13-,15- QEZAEHZBTXJQOF-CTYIDZIISA-N 158150 US9024044, 78::US9227949, 78 Enteropeptidase Homo sapiens 1.53 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158150&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044973 254815344 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355603 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-3-22(4-2,20(29)27-23(9-10-23)21(30)31)12-14-6-8-17(33-14)19(28)32-16-7-5-13(18(25)26)11-15(16)24/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,25,26)(H,27,29)(H,30,31) FJLPBYYWEBALPV-UHFFFAOYSA-N 158151 US9024044, 79::US9227949, 79 Enteropeptidase Homo sapiens 1.12 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158151&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044979 254815345 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355604 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-3-23(4-2,21(30)28-24(22(31)32)10-5-11-24)13-15-7-9-18(34-15)20(29)33-17-8-6-14(19(26)27)12-16(17)25/h6-9,12H,3-5,10-11,13H2,1-2H3,(H3,26,27)(H,28,30)(H,31,32) IZBCXOUJPXKGHT-UHFFFAOYSA-N 158152 US9024044, 80::US9227949, 80 Enteropeptidase Homo sapiens 1.33 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158152&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044980 254815346 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355605 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C21H24FN7O3S/c1-3-21(4-2,20(31)25-11-17-26-28-29-27-17)10-13-6-8-16(33-13)19(30)32-15-7-5-12(18(23)24)9-14(15)22/h5-9H,3-4,10-11H2,1-2H3,(H3,23,24)(H,25,31)(H,26,27,28,29) LJLCZQKLQRISET-UHFFFAOYSA-N 158153 BDBM308545::US9024044, 81::US9227949, 81 Enteropeptidase Homo sapiens 1.20 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158153&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90070125 254815347 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355606 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI=1S/C26H26FN3O6S/c1-3-26(4-2,25(35)30-15-6-8-19(31)17(12-15)23(32)33)13-16-7-10-21(37-16)24(34)36-20-9-5-14(22(28)29)11-18(20)27/h5-12,31H,3-4,13H2,1-2H3,(H3,28,29)(H,30,35)(H,32,33) VTJKUQVDQBWOCA-UHFFFAOYSA-N 199972 US9227949, 82 Enteropeptidase Homo sapiens 3.52 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199972&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998585 318589806 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355607 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O InChI=1S/C21H24FN3O5S/c1-3-21(4-2,20(29)25-11-17(26)27)10-13-6-8-16(31-13)19(28)30-15-7-5-12(18(23)24)9-14(15)22/h5-9H,3-4,10-11H2,1-2H3,(H3,23,24)(H,25,29)(H,26,27) XTZNPNPXVDSSKQ-UHFFFAOYSA-N 199973 US9227949, 83 Enteropeptidase Homo sapiens 0.72 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199973&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998587 318589807 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355608 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)c1nnn[nH]1 199974 BDBM308548::US9227949, 84 Enteropeptidase Homo sapiens 0.43 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199974&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998723 318589808 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355609 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CCC[C@H](C1)C(O)=O InChI=1S/C24H28FN3O5S/c1-24(2,23(32)28-15-5-3-4-14(10-15)21(29)30)12-16-7-9-19(34-16)22(31)33-18-8-6-13(20(26)27)11-17(18)25/h6-9,11,14-15H,3-5,10,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t14-,15+/m1/s1 HSVMLJWOQNTCAN-CABCVRRESA-N 199975 US9227949, 85 Enteropeptidase Homo sapiens 0.81 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199975&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998586 318589809 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355610 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1nn[nH]n1)C(O)=O 199976 US9227949, 86 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199976&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998588 318589810 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355611 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C17H17FN2O4S/c1-17(2,16(22)23)8-10-4-6-13(25-10)15(21)24-12-5-3-9(14(19)20)7-11(12)18/h3-7H,8H2,1-2H3,(H3,19,20)(H,22,23) NPDVBBRDXJPEMJ-UHFFFAOYSA-N 199977 US9227949, 87::US9655879, 87 Enteropeptidase Homo sapiens 0.39 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199977&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700236 318589811 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355612 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(C1)C(O)=O InChI=1S/C23H26FN3O5S/c1-3-23(4-2,22(31)27-11-14(12-27)20(28)29)10-15-6-8-18(33-15)21(30)32-17-7-5-13(19(25)26)9-16(17)24/h5-9,14H,3-4,10-12H2,1-2H3,(H3,25,26)(H,28,29) GIUBBIQNNZJOCU-UHFFFAOYSA-N 199978 US9227949, 88 Enteropeptidase Homo sapiens 1.00 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199978&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998589 318589812 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355613 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccc(c1)S(O)(=O)=O InChI=1S/C25H26FN3O6S2/c1-3-25(4-2,24(31)29-16-6-5-7-18(13-16)37(32,33)34)14-17-9-11-21(36-17)23(30)35-20-10-8-15(22(27)28)12-19(20)26/h5-13H,3-4,14H2,1-2H3,(H3,27,28)(H,29,31)(H,32,33,34) YTPAUABEQNQFGK-UHFFFAOYSA-N 199979 US9227949, 89::US9655879, 89 Enteropeptidase Homo sapiens 0.84 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199979&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998590 318589813 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355614 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O InChI=1S/C27H26FN3O7S/c1-3-27(4-2,26(37)31-15-6-8-17(23(32)33)18(12-15)24(34)35)13-16-7-10-21(39-16)25(36)38-20-9-5-14(22(29)30)11-19(20)28/h5-12H,3-4,13H2,1-2H3,(H3,29,30)(H,31,37)(H,32,33)(H,34,35) LUDVRKPPTTXHDS-UHFFFAOYSA-N 199980 US9227949, 90 Enteropeptidase Homo sapiens 0.55 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199980&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998591 318589814 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355615 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC[C@@H](C1)C(O)=O InChI=1S/C22H24FN3O5S/c1-22(2,21(30)26-8-7-13(11-26)19(27)28)10-14-4-6-17(32-14)20(29)31-16-5-3-12(18(24)25)9-15(16)23/h3-6,9,13H,7-8,10-11H2,1-2H3,(H3,24,25)(H,27,28)/t13-/m0/s1 XAKJOMCOYRMPIW-ZDUSSCGKSA-N 199981 US9227949, 91 Enteropeptidase Homo sapiens 0.90 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199981&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998592 318589815 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355616 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C(O)=O)c1ccc(O)cc1 InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m0/s1 XXVYMALEOOTBKD-FQEVSTJZSA-N 199982 US9227949, 92 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199982&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998593 318589816 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355617 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H](O)C[C@H]1C(O)=O InChI=1S/C22H24FN3O6S/c1-22(2,21(31)26-10-12(27)8-15(26)19(28)29)9-13-4-6-17(33-13)20(30)32-16-5-3-11(18(24)25)7-14(16)23/h3-7,12,15,27H,8-10H2,1-2H3,(H3,24,25)(H,28,29)/t12-,15+/m1/s1 SKGRPEWPALAWHA-DOMZBBRYSA-N 199983 US9227949, 93 Enteropeptidase Homo sapiens 0.30 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199983&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998594 318589817 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 355618 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC=CC[C@H]1C(O)=O InChI=1S/C24H26FN3O5S/c1-24(2,23(32)28-17-6-4-3-5-15(17)21(29)30)12-14-8-10-19(34-14)22(31)33-18-9-7-13(20(26)27)11-16(18)25/h3-4,7-11,15,17H,5-6,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)/t15-,17+/m1/s1 ZUOUVHHVZFOWTG-WBVHZDCISA-N 199984 US9227949, 94 Enteropeptidase Homo sapiens 1.30 8 US Patent 10.7270/Q2959GBT aid1802094 US9227949 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199984&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998595 318589818 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408246 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1 InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1 KSTWXAMIEVDBQH-JKSUJKDBSA-N 234237 US9346821, A-5 Enteropeptidase Homo sapiens 0.82 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234237&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491732 340094226 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408247 NC(=N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o3)ccc2c1 InChI=1S/C25H26N4O9S/c26-22(27)16-4-3-15-11-17(6-5-14(15)10-16)38-25(33)21-8-7-18(37-21)12-29-9-1-2-20(29)23(30)28-19(24(31)32)13-39(34,35)36/h3-8,10-11,19-20H,1-2,9,12-13H2,(H3,26,27)(H,28,30)(H,31,32)(H,34,35,36)/t19-,20+/m0/s1 NUFFEXHLLOWDJE-VQTJNVASSA-N 234238 US9346821, A-6 Enteropeptidase Homo sapiens 0.67 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234238&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491733 340094227 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408248 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o2)cc1 InChI=1S/C21H24N4O9S/c22-18(23)12-3-5-13(6-4-12)34-21(29)17-8-7-14(33-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16-/m0/s1 KSTWXAMIEVDBQH-HOTGVXAUSA-N 234239 US9346821, A-10 Enteropeptidase Homo sapiens 0.65 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234239&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491784 340094228 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408249 CC(C)[C@H](N(C)Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H28N4O8/c1-12(2)19(21(30)26-16(22(31)32)10-18(28)29)27(3)11-15-8-9-17(34-15)23(33)35-14-6-4-13(5-7-14)20(24)25/h4-9,12,16,19H,10-11H2,1-3H3,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t16-,19-/m0/s1 NZGUORWDBYYQCX-LPHOPBHVSA-N 234240 US9346821, A-14 Enteropeptidase Homo sapiens 0.56 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234240&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491785 340094229 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408250 CN(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H20N4O8/c1-23(19(29)22-13(17(26)27)8-15(24)25)9-12-6-7-14(30-12)18(28)31-11-4-2-10(3-5-11)16(20)21/h2-7,13H,8-9H2,1H3,(H3,20,21)(H,22,29)(H,24,25)(H,26,27)/t13-/m0/s1 IPAMUZPOGLKECI-ZDUSSCGKSA-N 234241 US9346821, A-20 Enteropeptidase Homo sapiens 0.94 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234241&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491786 340094230 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408251 CC(C)N(Cc1ccc(o1)C(=O)Oc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C21H24N4O8/c1-11(2)25(21(31)24-15(19(28)29)9-17(26)27)10-14-7-8-16(32-14)20(30)33-13-5-3-12(4-6-13)18(22)23/h3-8,11,15H,9-10H2,1-2H3,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t15-/m0/s1 YYQRIFRFLPLJFF-HNNXBMFYSA-N 234242 US9346821, A-21 Enteropeptidase Homo sapiens 0.38 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234242&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491787 340094231 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408252 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15-/m0/s1 UTVUAMNDZNEKQJ-GJZGRUSLSA-N 234243 US9346821, B-10 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234243&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491788 340094232 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408253 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1 InChI=1S/C23H25FN4O5S/c1-2-9-28(13-20(29)30)22(31)17-4-3-10-27(17)12-15-6-8-19(34-15)23(32)33-18-7-5-14(21(25)26)11-16(18)24/h2,5-8,11,17H,1,3-4,9-10,12-13H2,(H3,25,26)(H,29,30)/t17-/m0/s1 NNKCBNYPRAUWBJ-KRWDZBQOSA-N 234244 US9346821, B-11 Enteropeptidase Homo sapiens 0.78 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234244&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491840 340094233 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408254 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)cc1 InChI=1S/C21H24N4O8S2/c22-18(23)12-3-5-13(6-4-12)33-21(29)17-8-7-14(34-17)10-25-9-1-2-16(25)19(26)24-15(20(27)28)11-35(30,31)32/h3-8,15-16H,1-2,9-11H2,(H3,22,23)(H,24,26)(H,27,28)(H,30,31,32)/t15-,16+/m0/s1 ODSHFCIHAWDGHC-JKSUJKDBSA-N 234245 US9346821, B-12 Enteropeptidase Homo sapiens 0.95 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234245&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491841 340094234 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408255 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15+/m0/s1 CEBSLTBKCPYKRD-LSDHHAIUSA-N 234246 US9346821, B-13 Enteropeptidase Homo sapiens 0.43 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234246&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491842 340094235 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408256 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C21H23FN4O8S2/c22-13-8-11(18(23)24)3-5-16(13)34-21(30)17-6-4-12(35-17)9-26-7-1-2-15(26)19(27)25-14(20(28)29)10-36(31,32)33/h3-6,8,14-15H,1-2,7,9-10H2,(H3,23,24)(H,25,27)(H,28,29)(H,31,32,33)/t14-,15+/m0/s1 UTVUAMNDZNEKQJ-LSDHHAIUSA-N 234247 US9346821, B-14 Enteropeptidase Homo sapiens 0.24 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234247&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491843 340094236 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408257 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H23FN4O7S/c23-13-8-11(19(24)25)3-5-16(13)34-22(33)17-6-4-12(35-17)10-27-7-1-2-15(27)20(30)26-14(21(31)32)9-18(28)29/h3-6,8,14-15H,1-2,7,9-10H2,(H3,24,25)(H,26,30)(H,28,29)(H,31,32)/t14-,15-/m1/s1 CEBSLTBKCPYKRD-HUUCEWRRSA-N 234248 US9346821, B-15 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234248&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491844 340094237 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408258 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCCC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C23H25FN4O7S/c24-14-9-12(20(25)26)4-6-17(14)35-23(34)18-7-5-13(36-18)11-28-8-2-1-3-16(28)21(31)27-15(22(32)33)10-19(29)30/h4-7,9,15-16H,1-3,8,10-11H2,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,16-/m0/s1 IMLFZOQSBRIKFR-HOTGVXAUSA-N 234249 US9346821, B-18 Enteropeptidase Homo sapiens 0.44 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234249&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491902 340094238 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408259 NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C21H21FN4O7S2/c22-12-5-10(18(23)24)1-3-15(12)33-21(32)16-4-2-11(35-16)7-26-9-34-8-14(26)19(29)25-13(20(30)31)6-17(27)28/h1-5,13-14H,6-9H2,(H3,23,24)(H,25,29)(H,27,28)(H,30,31)/t13-,14-/m0/s1 RFEWBKIWAZDYIJ-KBPBESRZSA-N 234250 US9346821, B-20 Enteropeptidase Homo sapiens 0.15 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234250&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491903 340094239 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408260 NC(=N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N(CC=C)CC(O)=O)s2)c(F)c1 InChI=1S/C22H23FN4O5S2/c1-2-7-26(10-19(28)29)21(30)16-11-33-12-27(16)9-14-4-6-18(34-14)22(31)32-17-5-3-13(20(24)25)8-15(17)23/h2-6,8,16H,1,7,9-12H2,(H3,24,25)(H,28,29)/t16-/m0/s1 IWZOSZUOJFYGKM-INIZCTEOSA-N 234251 US9346821, B-21 Enteropeptidase Homo sapiens 1.00 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234251&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491904 340094240 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408261 CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19-/m0/s1 AEKXZFDUXYLPAD-KXBFYZLASA-N 234252 US9346821, B-23 Enteropeptidase Homo sapiens 0.75 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234252&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491905 340094241 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408263 CC(C)[C@@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H27FN4O7S/c1-11(2)19(21(31)27-15(22(32)33)9-18(29)30)28(3)10-13-5-7-17(36-13)23(34)35-16-6-4-12(20(25)26)8-14(16)24/h4-8,11,15,19H,9-10H2,1-3H3,(H3,25,26)(H,27,31)(H,29,30)(H,32,33)/t15-,19+/m0/s1 AEKXZFDUXYLPAD-HNAYVOBHSA-N 234254 US9346821, B-27 Enteropeptidase Homo sapiens 0.78 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234254&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491964 340094243 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408264 CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C28H29FN4O7S/c1-33(15-18-8-11-23(41-18)28(39)40-22-10-7-17(25(30)31)14-19(22)29)21(13-16-5-3-2-4-6-16)26(36)32-20(27(37)38)9-12-24(34)35/h2-8,10-11,14,20-21H,9,12-13,15H2,1H3,(H3,30,31)(H,32,36)(H,34,35)(H,37,38)/t20-,21-/m0/s1 BVOQHMQONHXLPX-SFTDATJTSA-N 234255 US9346821, B-29 Enteropeptidase Homo sapiens 0.38 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234255&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491965 340094244 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408265 CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18-/m0/s1 HZQWUEMGJWDFQJ-ROUUACIJSA-N 234256 US9346821, B-32 Enteropeptidase Homo sapiens 0.90 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234256&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491966 340094245 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408266 CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C24H29FN4O7S/c1-12(2)8-17(22(32)28-16(23(33)34)10-20(30)31)29(3)11-14-5-7-19(37-14)24(35)36-18-6-4-13(21(26)27)9-15(18)25/h4-7,9,12,16-17H,8,10-11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,17-/m0/s1 ANEXNSIWQCOUFR-IRXDYDNUSA-N 234257 US9346821, B-35 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234257&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491967 340094246 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408267 CC(C)C[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C25H31FN4O7S/c1-13(2)10-18(23(33)29-17(24(34)35)6-9-21(31)32)30(3)12-15-5-8-20(38-15)25(36)37-19-7-4-14(22(27)28)11-16(19)26/h4-5,7-8,11,13,17-18H,6,9-10,12H2,1-3H3,(H3,27,28)(H,29,33)(H,31,32)(H,34,35)/t17-,18+/m1/s1 HZQWUEMGJWDFQJ-MSOLQXFVSA-N 234258 US9346821, B-36 Enteropeptidase Homo sapiens 0.61 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234258&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491968 340094247 C06379 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408268 NC(=N)c1ccc(OC(=O)c2ccc(CNC3(CC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C21H21FN4O7S/c22-12-7-10(17(23)24)1-3-14(12)33-19(31)15-4-2-11(34-15)9-25-21(5-6-21)20(32)26-13(18(29)30)8-16(27)28/h1-4,7,13,25H,5-6,8-9H2,(H3,23,24)(H,26,32)(H,27,28)(H,29,30)/t13-/m0/s1 NQKQBMSNCHBXSB-ZDUSSCGKSA-N 234259 US9346821, B-37 Enteropeptidase Homo sapiens 1.27 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234259&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491115 340094248 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408269 CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C1(CCCC1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C24H27FN4O7S/c1-29(24(8-2-3-9-24)23(35)28-16(21(32)33)11-19(30)31)12-14-5-7-18(37-14)22(34)36-17-6-4-13(20(26)27)10-15(17)25/h4-7,10,16H,2-3,8-9,11-12H2,1H3,(H3,26,27)(H,28,35)(H,30,31)(H,32,33)/t16-/m0/s1 IARYBXOEYFPYKD-INIZCTEOSA-N 234260 US9346821, B-41 Enteropeptidase Homo sapiens 0.97 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234260&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491116 340094249 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408270 NC(=N)c1ccc(OC(=O)c2ccc(Cn3cccc3C(O)=O)s2)c(F)c1 InChI=1S/C18H14FN3O4S/c19-12-8-10(16(20)21)3-5-14(12)26-18(25)15-6-4-11(27-15)9-22-7-1-2-13(22)17(23)24/h1-8H,9H2,(H3,20,21)(H,23,24) FIQOBFTVRYSLKW-UHFFFAOYSA-N 234261 US9346821, B-42 Enteropeptidase Homo sapiens 0.61 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234261&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491117 340094250 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408271 NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(O)=O)Cc3s2)c(F)c1 InChI=1S/C17H16FN3O4S/c18-11-5-10(16(19)20)1-2-12(11)25-17(24)13-6-9-3-4-21(8-15(22)23)7-14(9)26-13/h1-2,5-6H,3-4,7-8H2,(H3,19,20)(H,22,23) IJJBKIGMTXLSCQ-UHFFFAOYSA-N 234262 US9346821, B-43 Enteropeptidase Homo sapiens 0.69 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234262&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491118 340094251 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408272 NC(=N)c1ccc(OC(=O)c2cc3CCN(CC(=O)N(CC=C)[C@@H](CCC(O)=O)C(O)=O)Cc3s2)c(F)c1 InChI=1S/C25H27FN4O7S/c1-2-8-30(17(24(34)35)4-6-22(32)33)21(31)13-29-9-7-14-11-19(38-20(14)12-29)25(36)37-18-5-3-15(23(27)28)10-16(18)26/h2-3,5,10-11,17H,1,4,6-9,12-13H2,(H3,27,28)(H,32,33)(H,34,35)/t17-/m0/s1 YGOVXCXVLNXXIA-KRWDZBQOSA-N 234263 US9346821, B-45 Enteropeptidase Homo sapiens 0.62 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234263&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491119 340094252 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408273 CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H19FN4O7S/c1-24(19(30)23-12(17(27)28)7-15(25)26)8-10-3-5-14(32-10)18(29)31-13-4-2-9(16(21)22)6-11(13)20/h2-6,12H,7-8H2,1H3,(H3,21,22)(H,23,30)(H,25,26)(H,27,28)/t12-/m0/s1 DERQIQYCRVEGJT-LBPRGKRZSA-N 234264 US9346821, B-46 Enteropeptidase Homo sapiens 0.38 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234264&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491120 340094253 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408274 CC(C)N(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C21H23FN4O7S/c1-10(2)26(21(32)25-14(19(29)30)8-17(27)28)9-12-4-6-16(34-12)20(31)33-15-5-3-11(18(23)24)7-13(15)22/h3-7,10,14H,8-9H2,1-2H3,(H3,23,24)(H,25,32)(H,27,28)(H,29,30)/t14-/m0/s1 OUPSVXGMAUFWPS-AWEZNQCLSA-N 234265 US9346821, B-47 Enteropeptidase Homo sapiens 0.33 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234265&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491177 340094254 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408275 NC(=N)c1ccc(OC(=O)c2cc3CCN(Cc3s2)C(=O)N[C@@H](CC(O)=O)C(O)=O)c(F)c1 InChI=1S/C20H19FN4O7S/c21-11-5-10(17(22)23)1-2-13(11)32-19(30)14-6-9-3-4-25(8-15(9)33-14)20(31)24-12(18(28)29)7-16(26)27/h1-2,5-6,12H,3-4,7-8H2,(H3,22,23)(H,24,31)(H,26,27)(H,28,29)/t12-/m0/s1 UMHVCSSJGIEZFT-LBPRGKRZSA-N 234266 US9346821, B-55 Enteropeptidase Homo sapiens 0.20 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234266&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71484067 340094255 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408276 NC(=N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CC=C)CC(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C24H25FN4O8S/c1-2-9-29(12-19(30)28-16(23(34)35)11-21(32)33)20(31)8-5-14-4-7-18(38-14)24(36)37-17-6-3-13(22(26)27)10-15(17)25/h2-4,6-7,10,16H,1,5,8-9,11-12H2,(H3,26,27)(H,28,30)(H,32,33)(H,34,35)/t16-/m0/s1 AMAJNJPVVXHSKF-INIZCTEOSA-N 234267 US9346821, B-56 Enteropeptidase Homo sapiens 0.77 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234267&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491178 340094256 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408277 CN(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C27H27FN4O7S/c1-32(20(11-15-5-3-2-4-6-15)25(35)31-19(26(36)37)13-23(33)34)14-17-8-10-22(40-17)27(38)39-21-9-7-16(24(29)30)12-18(21)28/h2-10,12,19-20H,11,13-14H2,1H3,(H3,29,30)(H,31,35)(H,33,34)(H,36,37)/t19-,20-/m1/s1 GCLKULRRQWOITN-WOJBJXKFSA-N 234268 US9346821, B-59 Enteropeptidase Homo sapiens 0.98 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234268&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90107147 340094257 C06380 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408278 NC(=N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N(CCC(O)=O)CC(O)=O)s2)c(F)c1 InChI=1S/C23H25FN4O7S/c24-15-10-13(21(25)26)3-5-17(15)35-23(34)18-6-4-14(36-18)11-27-8-1-2-16(27)22(33)28(12-20(31)32)9-7-19(29)30/h3-6,10,16H,1-2,7-9,11-12H2,(H3,25,26)(H,29,30)(H,31,32)/t16-/m1/s1 YKLFZFHHVZMCSE-MRXNPFEDSA-N 234269 US9346821, B-60 Enteropeptidase Homo sapiens 0.53 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234269&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90106335 340094258 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 408262 CC(C)[C@H](N(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C24H29FN4O7S/c1-12(2)20(22(32)28-16(23(33)34)6-9-19(30)31)29(3)11-14-5-8-18(37-14)24(35)36-17-7-4-13(21(26)27)10-15(17)25/h4-5,7-8,10,12,16,20H,6,9,11H2,1-3H3,(H3,26,27)(H,28,32)(H,30,31)(H,33,34)/t16-,20-/m0/s1 HLHMUJJGITWCBH-JXFKEZNVSA-N 234253 US9346821, B-26 Enteropeptidase Homo sapiens 1.00 8 US Patent 10.7270/Q2RB73G2 aid1802954 US9346821 Suzuki, T; Koshiba, T; Tokumasu, M; Ohsumi, K Ajinomoto Co. Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234253&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 71491906 340094242 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591835 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/m0/s1 CHAXFLSDNLDWPP-AWEZNQCLSA-N 158073 US9024044, 1::US9227949, 1::US9655879, 1 Enteropeptidase Homo sapiens 0.140 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158073&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699917 254815267 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591837 NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 InChI=1S/C23H24FN3O7S/c24-14-9-12(19(25)26)3-5-16(14)34-21(32)17-6-4-13(35-17)11-23(7-1-2-8-23)22(33)27-15(20(30)31)10-18(28)29/h3-6,9,15H,1-2,7-8,10-11H2,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/m0/s1 HXDKJHJAMFQXBA-HNNXBMFYSA-N 158074 US9024044, 2::US9227949, 2::US9655879, 2 Enteropeptidase Homo sapiens 0.730 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158074&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90019132 254815268 C02715 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591839 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O InChI=1S/C19H20FN3O5S/c1-19(2,18(27)23-9-15(24)25)8-11-4-6-14(29-11)17(26)28-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,27)(H,24,25) FBFZNZYSXBOYCU-UHFFFAOYSA-N 308123 US9655879, 3 Enteropeptidase Homo sapiens 0.290 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308123&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796565 382364194 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591841 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C20H22FN3O6S/c1-20(2,19(29)24-13(9-25)17(26)27)8-11-4-6-15(31-11)18(28)30-14-5-3-10(16(22)23)7-12(14)21/h3-7,13,25H,8-9H2,1-2H3,(H3,22,23)(H,24,29)(H,26,27)/t13-/m0/s1 PGOXWLZRNRRTHV-ZDUSSCGKSA-N 158076 US9024044, 4::US9227949, 4::US9655879, 4 Enteropeptidase Homo sapiens 0.460 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158076&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699919 254815270 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591843 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28) XYNSVADDWDUDBJ-UHFFFAOYSA-N 158077 US9024044, 5::US9227949, 5::US9655879, 5 Enteropeptidase Homo sapiens 0.240 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158077&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699920 254815271 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591845 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(C)(C)C(O)=O InChI=1S/C21H24FN3O5S/c1-20(2,18(27)25-21(3,4)19(28)29)10-12-6-8-15(31-12)17(26)30-14-7-5-11(16(23)24)9-13(14)22/h5-9H,10H2,1-4H3,(H3,23,24)(H,25,27)(H,28,29) CXAAAVDPZVTHHD-UHFFFAOYSA-N 158078 US9024044, 6::US9227949, 6::US9655879, 6 Enteropeptidase Homo sapiens 0.690 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158078&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699921 254815272 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591847 CN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H22FN3O5S/c1-20(2,19(28)24(3)10-16(25)26)9-12-5-7-15(30-12)18(27)29-14-6-4-11(17(22)23)8-13(14)21/h4-8H,9-10H2,1-3H3,(H3,22,23)(H,25,26) LWAVAXQFRSKGMV-UHFFFAOYSA-N 158079 US9024044, 7::US9227949, 7::US9655879, 7 Enteropeptidase Homo sapiens 0.410 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158079&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044933 254815273 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591849 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C22H24FN3O5S.ClH/c1-22(2,21(30)26-9-3-4-15(26)19(27)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23;/h5-8,10,15H,3-4,9,11H2,1-2H3,(H3,24,25)(H,27,28);1H/t15-;/m0./s1 RWEOGEGGSMUMMS-RSAXXLAASA-N 308240 US9655879, 8 Enteropeptidase Homo sapiens 0.870 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308240&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796567 382364309 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591851 Cl.CC(C)[C@H](NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C22H26FN3O5S.ClH/c1-11(2)17(19(27)28)26-21(30)22(3,4)10-13-6-8-16(32-13)20(29)31-15-7-5-12(18(24)25)9-14(15)23;/h5-9,11,17H,10H2,1-4H3,(H3,24,25)(H,26,30)(H,27,28);1H/t17-;/m0./s1 XODIBEXXMFUDRX-LMOVPXPDSA-N 308241 US9655879, 9 Enteropeptidase Homo sapiens 0.790 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308241&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018772 382364310 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591853 Cl.CCCN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H26FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h5-8,10H,4,9,11-12H2,1-3H3,(H3,24,25)(H,27,28) VCKIEANVSOSDBH-UHFFFAOYSA-N 308242 US9655879, 10 Enteropeptidase Homo sapiens 0.490 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308242&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018963 382364311 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591855 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C22H26FN3O6S.ClH/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23;/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29);1H/t15-;/m0./s1 HGQFNRYUTAPKGR-RSAXXLAASA-N 308247 US9655879, 11 Enteropeptidase Homo sapiens 0.410 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308247&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90019082 382364316 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591857 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CO)C(O)=O InChI=1S/C22H26FN3O6S.ClH/c1-3-22(4-2,21(31)26-15(11-27)19(28)29)10-13-6-8-17(33-13)20(30)32-16-7-5-12(18(24)25)9-14(16)23;/h5-9,15,27H,3-4,10-11H2,1-2H3,(H3,24,25)(H,26,31)(H,28,29);1H/t15-;/m1./s1 HGQFNRYUTAPKGR-XFULWGLBSA-N 308248 US9655879, 12 Enteropeptidase Homo sapiens 0.940 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308248&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796568 382364317 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591859 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C24H30FN3O5S.ClH/c1-5-24(6-2,23(32)28-19(13(3)4)21(29)30)12-15-8-10-18(34-15)22(31)33-17-9-7-14(20(26)27)11-16(17)25;/h7-11,13,19H,5-6,12H2,1-4H3,(H3,26,27)(H,28,32)(H,29,30);1H/t19-;/m0./s1 IOCUTDQIIDJUQQ-FYZYNONXSA-N 308250 US9655879, 13 Enteropeptidase Homo sapiens 1.56 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308250&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796569 382364319 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591861 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC(O)=O InChI=1S/C22H26FN3O5S/c1-3-22(4-2,21(30)26-10-9-18(27)28)12-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)11-15(16)23/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,24,25)(H,26,30)(H,27,28) RMZDNEFSCYWLFZ-UHFFFAOYSA-N 308253 US9655879, 14 Enteropeptidase Homo sapiens 0.990 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308253&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796570 382364322 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591863 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(C)O)C(O)=O InChI=1S/C23H28FN3O6S.ClH/c1-4-23(5-2,22(32)27-18(12(3)28)20(29)30)11-14-7-9-17(34-14)21(31)33-16-8-6-13(19(25)26)10-15(16)24;/h6-10,12,18,28H,4-5,11H2,1-3H3,(H3,25,26)(H,27,32)(H,29,30);1H/t12?,18-;/m0./s1 GSJJCSBNFSGFKZ-PPQCBMEVSA-N 308321 US9655879, 15 Enteropeptidase Homo sapiens 0.840 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308321&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796571 382364390 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591865 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C28H30FN3O5S.ClH/c1-3-28(4-2,27(36)32-21(25(33)34)14-17-8-6-5-7-9-17)16-19-11-13-23(38-19)26(35)37-22-12-10-18(24(30)31)15-20(22)29;/h5-13,15,21H,3-4,14,16H2,1-2H3,(H3,30,31)(H,32,36)(H,33,34);1H/t21-;/m0./s1 CEZWJPSAROOVPE-BOXHHOBZSA-N 308322 US9655879, 16 Enteropeptidase Homo sapiens 1.10 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308322&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796572 382364391 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591867 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1C(O)=O InChI=1S/C24H28FN3O5S.ClH/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25;/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30);1H/t17-;/m0./s1 ORIDEVHIFOZWIV-LMOVPXPDSA-N 308323 US9655879, 17 Enteropeptidase Homo sapiens 1.69 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308323&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796573 382364392 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591869 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C19H21FN2O4S/c1-3-19(4-2,18(24)25)10-12-6-8-15(27-12)17(23)26-14-7-5-11(16(21)22)9-13(14)20/h5-9H,3-4,10H2,1-2H3,(H3,21,22)(H,24,25) NVBTXQNZNQVUIV-UHFFFAOYSA-N 158090 US9024044, 18::US9227949, 18::US9655879, 18 Enteropeptidase Homo sapiens 1.24 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158090&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72699996 254815284 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591871 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S.ClH/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24;/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31);1H/t15-;/m0./s1 ZVWCKYMMMNXSAC-RSAXXLAASA-N 308401 US9655879, 19 Enteropeptidase Homo sapiens 0.330 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308401&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72543743 382364470 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591873 Cl.CCCN(CC(O)=O)C(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C24H30FN3O5S/c1-4-11-28(14-20(29)30)23(32)24(5-2,6-3)13-16-8-10-19(34-16)22(31)33-18-9-7-15(21(26)27)12-17(18)25/h7-10,12H,4-6,11,13-14H2,1-3H3,(H3,26,27)(H,29,30) QRSQMHVQHCFHOA-UHFFFAOYSA-N 308403 US9655879, 20 Enteropeptidase Homo sapiens 2.61 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308403&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796574 382364472 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591875 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(C)CC(O)=O InChI=1S/C22H26FN3O5S/c1-4-22(5-2,21(30)26(3)12-18(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(19(24)25)10-15(16)23/h6-10H,4-5,11-12H2,1-3H3,(H3,24,25)(H,27,28) JGFFFJLERKVFRG-UHFFFAOYSA-N 308407 US9655879, 21 Enteropeptidase Homo sapiens 0.880 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308407&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90018821 382364476 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591877 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@@H]1C(O)=O InChI=1S/C24H28FN3O5S.ClH/c1-3-24(4-2,23(32)28-11-5-6-17(28)21(29)30)13-15-8-10-19(34-15)22(31)33-18-9-7-14(20(26)27)12-16(18)25;/h7-10,12,17H,3-6,11,13H2,1-2H3,(H3,26,27)(H,29,30);1H/t17-;/m1./s1 ORIDEVHIFOZWIV-UNTBIKODSA-N 308425 US9655879, 22 Enteropeptidase Homo sapiens 1.000 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308425&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796576 382364493 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591879 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CCS(O)(=O)=O)CC=C InChI=1S/C22H26FN3O6S2/c1-4-9-26(10-11-34(29,30)31)21(28)22(2,3)13-15-6-8-18(33-15)20(27)32-17-7-5-14(19(24)25)12-16(17)23/h4-8,12H,1,9-11,13H2,2-3H3,(H3,24,25)(H,29,30,31) DULSYBFZNKGICA-UHFFFAOYSA-N 158095 US9024044, 23::US9227949, 23::US9655879, 23 Enteropeptidase Homo sapiens 1.81 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158095&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90017966 254815289 C15521 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591881 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S.ClH/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25;/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32);1H/t16-;/m0./s1 ASCMVBGGEBCPSH-NTISSMGPSA-N 308428 US9655879, 24 Enteropeptidase Homo sapiens 0.270 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308428&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796577 382364496 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591883 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O InChI=1S/C23H26FN3O7S.ClH/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24;/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31);1H/t15-;/m1./s1 ZVWCKYMMMNXSAC-XFULWGLBSA-N 308429 US9655879, 25 Enteropeptidase Homo sapiens 0.260 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308429&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796578 382364497 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591885 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27-9-7-13(8-10-27)20(28)29)12-15-4-6-18(33-15)21(30)32-17-5-3-14(19(25)26)11-16(17)24/h3-6,11,13H,7-10,12H2,1-2H3,(H3,25,26)(H,28,29) JKGGZKLIDGJKFW-UHFFFAOYSA-N 308430 US9655879, 26 Enteropeptidase Homo sapiens 1.33 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308430&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796579 382364498 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591887 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C)C(O)=O InChI=1S/C22H26FN3O5S.ClH/c1-4-22(5-2,21(30)26-12(3)19(27)28)11-14-7-9-17(32-14)20(29)31-16-8-6-13(18(24)25)10-15(16)23;/h6-10,12H,4-5,11H2,1-3H3,(H3,24,25)(H,26,30)(H,27,28);1H/t12-;/m0./s1 IYHCMEVZCKUPOX-YDALLXLXSA-N 308435 US9655879, 27 Enteropeptidase Homo sapiens 0.730 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308435&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796580 382364503 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591889 Cl.CC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C23H28FN3O5S.ClH/c1-4-16(20(28)29)27-22(31)23(5-2,6-3)12-14-8-10-18(33-14)21(30)32-17-9-7-13(19(25)26)11-15(17)24;/h7-11,16H,4-6,12H2,1-3H3,(H3,25,26)(H,27,31)(H,28,29);1H/t16-;/m0./s1 UZFNNOPLIFSUBY-NTISSMGPSA-N 308444 US9655879, 28 Enteropeptidase Homo sapiens 0.650 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308444&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796581 382364512 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591891 Cl.CCC[C@H](NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C24H30FN3O5S.ClH/c1-4-7-17(21(29)30)28-23(32)24(5-2,6-3)13-15-9-11-19(34-15)22(31)33-18-10-8-14(20(26)27)12-16(18)25;/h8-12,17H,4-7,13H2,1-3H3,(H3,26,27)(H,28,32)(H,29,30);1H/t17-;/m0./s1 AINVUARQIOIBOO-LMOVPXPDSA-N 308445 US9655879, 29 Enteropeptidase Homo sapiens 1.18 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308445&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796582 382364513 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591893 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCC(O)=O InChI=1S/C23H28FN3O5S/c1-3-23(4-2,22(31)27-11-5-6-19(28)29)13-15-8-10-18(33-15)21(30)32-17-9-7-14(20(25)26)12-16(17)24/h7-10,12H,3-6,11,13H2,1-2H3,(H3,25,26)(H,27,31)(H,28,29) HTXAFJRASQGRGV-UHFFFAOYSA-N 308494 US9655879, 30 Enteropeptidase Homo sapiens 0.940 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308494&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796583 382364562 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591895 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) QWJBPYHICUEKBK-UHFFFAOYSA-N 308495 US9655879, 31 Enteropeptidase Homo sapiens 1.08 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308495&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796584 382364563 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591897 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccc(c1)C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-15-5-3-4-14(10-15)21(29)30)12-16-7-9-19(34-16)22(31)33-18-8-6-13(20(26)27)11-17(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) GITALEQGUYRJGX-UHFFFAOYSA-N 308496 US9655879, 32 Enteropeptidase Homo sapiens 1.43 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308496&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796585 382364564 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591899 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC[C@H](C1)C(O)=O InChI=1S/C22H24FN3O5S.ClH/c1-22(2,21(30)26-8-7-13(11-26)19(27)28)10-14-4-6-17(32-14)20(29)31-16-5-3-12(18(24)25)9-15(16)23;/h3-6,9,13H,7-8,10-11H2,1-2H3,(H3,24,25)(H,27,28);1H/t13-;/m1./s1 PPTUCEHTBRKENK-BTQNPOSSSA-N 308497 US9655879, 33 Enteropeptidase Homo sapiens 1.02 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308497&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796586 382364565 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591901 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H]1COC(=O)C1 InChI=1S/C23H26FN3O5S.ClH/c1-3-23(4-2,22(30)27-14-10-19(28)31-12-14)11-15-6-8-18(33-15)21(29)32-17-7-5-13(20(25)26)9-16(17)24;/h5-9,14H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,30);1H/t14-;/m0./s1 KTPJAWHLYWQMKP-UQKRIMTDSA-N 308498 US9655879, 34 Enteropeptidase Homo sapiens 2.56 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308498&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796587 382364566 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591903 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 YGHKECGTVWVLDI-FQEVSTJZSA-N 158107 US9024044, 35::US9227949, 35::US9655879, 35 Enteropeptidase Homo sapiens 2.56 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158107&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044949 254815301 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591905 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C1CCCCC1)C(O)=O InChI=1S/C25H30FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h8-12,14,20H,3-7,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 YGHKECGTVWVLDI-HXUWFJFHSA-N 158108 US9024044, 36::US9227949, 36::US9655879, 36 Enteropeptidase Homo sapiens 4.70 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158108&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044950 254815302 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591907 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m0/s1 LFNPOEKMAAWLGP-FQEVSTJZSA-N 158109 US9024044, 37::US9227949, 37::US9655879, 37 Enteropeptidase Homo sapiens 0.960 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158109&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044951 254815303 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591909 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccccc1 InChI=1S/C25H24FN3O5S/c1-25(2,24(33)29-20(22(30)31)14-6-4-3-5-7-14)13-16-9-11-19(35-16)23(32)34-18-10-8-15(21(27)28)12-17(18)26/h3-12,20H,13H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)/t20-/m1/s1 LFNPOEKMAAWLGP-HXUWFJFHSA-N 158110 US9024044, 38::US9227949, 38::US9655879, 38 Enteropeptidase Homo sapiens 0.970 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158110&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044952 254815304 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591911 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccnc1 InChI=1S/C22H21FN4O3S/c1-22(2,21(29)27-14-4-3-9-26-12-14)11-15-6-8-18(31-15)20(28)30-17-7-5-13(19(24)25)10-16(17)23/h3-10,12H,11H2,1-2H3,(H3,24,25)(H,27,29) GNBPVACYKKHTJB-UHFFFAOYSA-N 158111 US9024044, 39::US9227949, 39::US9655879, 39 Enteropeptidase Homo sapiens 7.56 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158111&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044953 254815305 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591913 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc[nH]c1=O InChI=1S/C22H21FN4O4S/c1-22(2,21(30)27-15-4-3-9-26-19(15)28)11-13-6-8-17(32-13)20(29)31-16-7-5-12(18(24)25)10-14(16)23/h3-10H,11H2,1-2H3,(H3,24,25)(H,26,28)(H,27,30) HKARKNAVVKQMPE-UHFFFAOYSA-N 158112 US9024044, 40::US9227949, 40::US9655879, 40 Enteropeptidase Homo sapiens 6.66 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158112&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044954 254815306 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591915 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCC[C@H]1CC(O)=O InChI=1S/C23H26FN3O5S.ClH/c1-23(2,22(31)27-9-3-4-14(27)11-19(28)29)12-15-6-8-18(33-15)21(30)32-17-7-5-13(20(25)26)10-16(17)24;/h5-8,10,14H,3-4,9,11-12H2,1-2H3,(H3,25,26)(H,28,29);1H/t14-;/m0./s1 KNRWJAKUEACCNU-UQKRIMTDSA-N 308505 US9655879, 41 Enteropeptidase Homo sapiens 1.58 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308505&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796588 382364573 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591917 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C24H29FN4O6S/c1-3-24(4-2,23(34)29-16(21(31)32)7-10-19(26)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(27)28)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H2,26,30)(H3,27,28)(H,29,34)(H,31,32)/t16-/m0/s1 VSKNKWMUXQDPKJ-INIZCTEOSA-N 158114 US9024044, 42::US9227949, 42::US9655879, 42 Enteropeptidase Homo sapiens 1.69 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158114&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044955 254815308 C02716 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591919 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CCC(O)=O)C(O)=O InChI=1S/C24H28FN3O7S.ClH/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25;/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32);1H/t16-;/m1./s1 ASCMVBGGEBCPSH-PKLMIRHRSA-N 308507 US9655879, 43 Enteropeptidase Homo sapiens 0.420 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308507&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796589 382364575 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591921 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C23H27FN4O6S.ClH/c1-3-23(4-2,22(33)28-15(20(30)31)10-18(25)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(26)27)9-14(16)24;/h5-9,15H,3-4,10-11H2,1-2H3,(H2,25,29)(H3,26,27)(H,28,33)(H,30,31);1H/t15-;/m0./s1 XGJWESDXGURGJX-RSAXXLAASA-N 308508 US9655879, 44 Enteropeptidase Homo sapiens 0.670 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308508&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796590 382364576 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591923 COc1ccc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cn1 InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-14-5-9-19(31-3)27-12-14)11-15-6-8-18(33-15)21(29)32-17-7-4-13(20(25)26)10-16(17)24/h4-10,12H,11H2,1-3H3,(H3,25,26)(H,28,30) GGORVCBBPWZASH-UHFFFAOYSA-N 158117 US9024044, 45::US9227949, 45::US9655879, 45 Enteropeptidase Homo sapiens 4.13 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158117&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044957 254815311 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591925 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(F)(F)C1 InChI=1S/C20H20F3N3O3S/c1-19(2,18(28)26-9-20(22,23)10-26)8-12-4-6-15(30-12)17(27)29-14-5-3-11(16(24)25)7-13(14)21/h3-7H,8-10H2,1-2H3,(H3,24,25) MBNRUFIEUAXHGI-UHFFFAOYSA-N 158118 US9024044, 46::US9227949, 46::US9655879, 46 Enteropeptidase Homo sapiens 5.27 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158118&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044958 254815312 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591927 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI=1S/C24H22FN3O6S/c1-24(2,23(33)28-13-4-6-17(29)15(10-13)21(30)31)11-14-5-8-19(35-14)22(32)34-18-7-3-12(20(26)27)9-16(18)25/h3-10,29H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) SLSLVLFFHMCGMN-UHFFFAOYSA-N 308511 US9655879, 47 Enteropeptidase Homo sapiens 0.530 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308511&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796591 382364579 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591929 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(CC(O)=O)cc1 InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-18-8-5-16(6-9-18)13-23(32)33)15-19-10-12-22(37-19)25(34)36-21-11-7-17(24(29)30)14-20(21)28/h5-12,14H,3-4,13,15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) FMQUCBATRXHMPW-UHFFFAOYSA-N 308512 US9655879, 48 Enteropeptidase Homo sapiens 2.41 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308512&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796592 382364580 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591931 Cl.CCC(C)[C@@H](CC(O)=O)NC(=O)C(CC)(CC)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C26H34FN3O5S.ClH/c1-5-15(4)19(13-22(31)32)30-25(34)26(6-2,7-3)14-17-9-11-21(36-17)24(33)35-20-10-8-16(23(28)29)12-18(20)27;/h8-12,15,19H,5-7,13-14H2,1-4H3,(H3,28,29)(H,30,34)(H,31,32);1H/t15?,19-;/m1./s1 AHVCLHIIDXARTR-SAQPSMIMSA-N 308513 US9655879, 49 Enteropeptidase Homo sapiens 3.26 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308513&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796593 382364581 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591933 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CCc2ccc(cc2C1)C(O)=O InChI=1S/C27H26FN3O5S/c1-27(2,26(35)31-10-9-15-3-4-17(24(32)33)11-18(15)14-31)13-19-6-8-22(37-19)25(34)36-21-7-5-16(23(29)30)12-20(21)28/h3-8,11-12H,9-10,13-14H2,1-2H3,(H3,29,30)(H,32,33) VUDQLRYFBDWFRC-UHFFFAOYSA-N 158122 US9024044, 50::US9227949, 50::US9655879, 50 Enteropeptidase Homo sapiens 3.46 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158122&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044961 254815316 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591935 COc1ncccc1NC(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H23FN4O4S/c1-23(2,22(30)28-16-5-4-10-27-20(16)31-3)12-14-7-9-18(33-14)21(29)32-17-8-6-13(19(25)26)11-15(17)24/h4-11H,12H2,1-3H3,(H3,25,26)(H,28,30) VQICKBIEIBEKAP-UHFFFAOYSA-N 158123 US9024044, 51::US9227949, 51::US9655879, 51 Enteropeptidase Homo sapiens 3.75 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158123&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044962 254815317 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591937 Cl.Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC[C@H](N)C(O)=O InChI=1S/C24H31FN4O5S.2ClH/c1-3-24(4-2,23(33)29-11-5-6-17(26)21(30)31)13-15-8-10-19(35-15)22(32)34-18-9-7-14(20(27)28)12-16(18)25;;/h7-10,12,17H,3-6,11,13,26H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31);2*1H/t17-;;/m0../s1 PNPPHJXROXYUDZ-RMRYJAPISA-N 308516 US9655879, 52 Enteropeptidase Homo sapiens 5.53 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308516&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796594 382364584 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591939 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1ccc(cc1)C(O)=O InChI=1S/C27H28FN3O5S/c1-3-27(4-2,26(35)31-15-16-5-7-17(8-6-16)24(32)33)14-19-10-12-22(37-19)25(34)36-21-11-9-18(23(29)30)13-20(21)28/h5-13H,3-4,14-15H2,1-2H3,(H3,29,30)(H,31,35)(H,32,33) UCVYMBGYTGPRBW-UHFFFAOYSA-N 308517 US9655879, 53 Enteropeptidase Homo sapiens 2.69 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308517&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796595 382364585 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591941 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26) NWTMDNVGALXRNH-UHFFFAOYSA-N 308518 US9655879, 54 Enteropeptidase Homo sapiens 1.76 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308518&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 118909042 382364586 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591943 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(F)nc1 InChI=1S/C22H20F2N4O3S/c1-22(2,21(30)28-13-4-8-18(24)27-11-13)10-14-5-7-17(32-14)20(29)31-16-6-3-12(19(25)26)9-15(16)23/h3-9,11H,10H2,1-2H3,(H3,25,26)(H,28,30) HPQNZKOUBYGLOW-UHFFFAOYSA-N 158127 US9024044, 55::US9227949, 55::US9655879, 55 Enteropeptidase Homo sapiens 2.51 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158127&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044966 254815321 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591945 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C22H24FN3O5S/c1-21(2,19(28)26-22(20(29)30)8-3-9-22)11-13-5-7-16(32-13)18(27)31-15-6-4-12(17(24)25)10-14(15)23/h4-7,10H,3,8-9,11H2,1-2H3,(H3,24,25)(H,26,28)(H,29,30) YRTBCUYEEWAYIN-UHFFFAOYSA-N 308520 US9655879, 56 Enteropeptidase Homo sapiens 0.510 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308520&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796596 382364588 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591947 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C21H22FN3O5S/c1-20(2,18(27)25-21(7-8-21)19(28)29)10-12-4-6-15(31-12)17(26)30-14-5-3-11(16(23)24)9-13(14)22/h3-6,9H,7-8,10H2,1-2H3,(H3,23,24)(H,25,27)(H,28,29) NQWKELPUBUTTAS-UHFFFAOYSA-N 308521 US9655879, 57 Enteropeptidase Homo sapiens 0.670 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308521&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796597 382364589 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591949 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC(CCC(O)=O)(CCC(O)=O)CCC(O)=O InChI=1S/C27H32FN3O9S/c1-26(2,25(39)31-27(10-7-20(32)33,11-8-21(34)35)12-9-22(36)37)14-16-4-6-19(41-16)24(38)40-18-5-3-15(23(29)30)13-17(18)28/h3-6,13H,7-12,14H2,1-2H3,(H3,29,30)(H,31,39)(H,32,33)(H,34,35)(H,36,37) ARRGOUAMPKSURR-UHFFFAOYSA-N 158130 US9024044, 58::US9227949, 58::US9655879, 58 Enteropeptidase Homo sapiens 0.710 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158130&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700148 254815324 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591951 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) WDYKMWXZCPOZKO-UHFFFAOYSA-N 158131 US9024044, 59::US9227949, 59::US9655879, 59 Enteropeptidase Homo sapiens 0.310 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158131&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700149 254815325 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591953 COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(s2)C(=O)Oc2ccc(cc2F)C(N)=N)cc(c1)C(=O)OC InChI=1S/C27H26FN3O7S/c1-27(2,26(35)31-17-10-15(23(32)36-3)9-16(11-17)24(33)37-4)13-18-6-8-21(39-18)25(34)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,13H2,1-4H3,(H3,29,30)(H,31,35) UHWHRMYFHIAVQB-UHFFFAOYSA-N 158132 US9024044, 60::US9227949, 60::US9655879, 60 Enteropeptidase Homo sapiens 1.22 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158132&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044968 254815326 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591955 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H]1C(O)=O InChI=1S/C20H20FN3O5S/c1-20(2,19(28)24-9-13(24)17(25)26)8-11-4-6-15(30-11)18(27)29-14-5-3-10(16(22)23)7-12(14)21/h3-7,13H,8-9H2,1-2H3,(H3,22,23)(H,25,26)/t13-,24?/m0/s1 NWTMDNVGALXRNH-LNHXHEARSA-N 158133 US9024044, 61::US9227949, 61::US9655879, 61 Enteropeptidase Homo sapiens 1.13 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158133&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044969 254815327 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591957 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCC(O)=O InChI=1S/C24H30FN3O5S/c1-3-24(4-2,23(32)28-12-6-5-7-20(29)30)14-16-9-11-19(34-16)22(31)33-18-10-8-15(21(26)27)13-17(18)25/h8-11,13H,3-7,12,14H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) JBHHRVQRHSBNTN-UHFFFAOYSA-N 308526 US9655879, 62 Enteropeptidase Homo sapiens 0.980 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308526&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796598 382364594 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591959 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCC#N InChI=1S/C20H21FN4O3S/c1-20(2,19(27)25-9-3-8-22)11-13-5-7-16(29-13)18(26)28-15-6-4-12(17(23)24)10-14(15)21/h4-7,10H,3,9,11H2,1-2H3,(H3,23,24)(H,25,27) NCNMXHNAIQAZJK-UHFFFAOYSA-N 308527 US9655879, 63 Enteropeptidase Homo sapiens 2.90 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308527&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796599 382364595 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591961 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCc1nnn[nH]1 InChI=1S/C20H22FN7O3S/c1-20(2,19(30)24-8-7-16-25-27-28-26-16)10-12-4-6-15(32-12)18(29)31-14-5-3-11(17(22)23)9-13(14)21/h3-6,9H,7-8,10H2,1-2H3,(H3,22,23)(H,24,30)(H,25,26,27,28) ASUXORKUDJSWOW-UHFFFAOYSA-N 308528 US9655879, 64 Enteropeptidase Homo sapiens 0.530 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308528&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796600 382364596 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591963 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C19H20FN7O3S/c1-19(2,18(29)23-9-15-24-26-27-25-15)8-11-4-6-14(31-11)17(28)30-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,29)(H,24,25,26,27) UQNVEJVKVQTREV-UHFFFAOYSA-N 158137 BDBM308529::US9024044, 65::US9227949, 65 Enteropeptidase Homo sapiens 0.530 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158137&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700231 254815331 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591965 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O InChI=1S/C27H26FN3O7S/c1-3-27(4-2,26(37)31-17-10-15(23(32)33)9-16(11-17)24(34)35)13-18-6-8-21(39-18)25(36)38-20-7-5-14(22(29)30)12-19(20)28/h5-12H,3-4,13H2,1-2H3,(H3,29,30)(H,31,37)(H,32,33)(H,34,35) NEIQENFRFQTURN-UHFFFAOYSA-N 158138 US9024044, 66::US9227949, 66::US9655879, 66 Enteropeptidase Homo sapiens 0.710 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158138&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700232 254815332 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591967 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(=O)OC)C(O)=O InChI=1S/C28H28FN3O7S/c1-4-28(5-2,27(37)32-18-11-16(24(33)34)10-17(12-18)25(35)38-3)14-19-7-9-22(40-19)26(36)39-21-8-6-15(23(30)31)13-20(21)29/h6-13H,4-5,14H2,1-3H3,(H3,30,31)(H,32,37)(H,33,34) OXNWGHGTGKAZFK-UHFFFAOYSA-N 158139 US9024044, 67::US9227949, 67::US9655879, 67 Enteropeptidase Homo sapiens 3.73 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158139&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044972 254815333 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591969 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) PPLWQAMMKNZODE-UHFFFAOYSA-N 158140 US9024044, 68::US9227949, 68::US9655879, 68 Enteropeptidase Homo sapiens 0.240 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158140&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700233 254815334 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591971 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 InChI=1S/C25H24FN3O6S/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32)/t20-/m1/s1 XXVYMALEOOTBKD-HXUWFJFHSA-N 158141 US9024044, 69::US9227949, 69::US9655879, 69 Enteropeptidase Homo sapiens 0.720 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158141&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700234 254815335 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591973 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S.ClH/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25;/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30);1H/t13-,15+; SUCPQVSYINREFE-FTSBBCAASA-N 308534 US9655879, 70 Enteropeptidase Homo sapiens 1.11 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308534&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796601 382364602 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591975 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCCCCCC(O)=O InChI=1S/C25H32FN3O5S/c1-3-25(4-2,24(33)29-13-7-5-6-8-21(30)31)15-17-10-12-20(35-17)23(32)34-19-11-9-16(22(27)28)14-18(19)26/h9-12,14H,3-8,13,15H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31) ACEUOZVTHUQNKZ-UHFFFAOYSA-N 308535 US9655879, 71 Enteropeptidase Homo sapiens 4.97 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308535&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796602 382364603 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591977 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(C1)C(O)=O InChI=1S/C21H22FN3O5S/c1-21(2,20(29)25-9-12(10-25)18(26)27)8-13-4-6-16(31-13)19(28)30-15-5-3-11(17(23)24)7-14(15)22/h3-7,12H,8-10H2,1-2H3,(H3,23,24)(H,26,27) PRXOELBXTGUDLM-UHFFFAOYSA-N 158144 US9024044, 72::US9227949, 72::US9655879, 72 Enteropeptidase Homo sapiens 0.630 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158144&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700235 254815338 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591979 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccccc1C(O)=O InChI=1S/C24H22FN3O5S/c1-24(2,23(32)28-17-6-4-3-5-15(17)21(29)30)12-14-8-10-19(34-14)22(31)33-18-9-7-13(20(26)27)11-16(18)25/h3-11H,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30) NRLONGNAKYXRSF-UHFFFAOYSA-N 308537 US9655879, 73 Enteropeptidase Homo sapiens 2.41 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308537&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796603 382364605 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591981 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31) WBRGSXXRFXKGIY-UHFFFAOYSA-N 158146 US9024044, 74::US9227949, 74::US9655879, 74 Enteropeptidase Homo sapiens 0.580 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158146&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 102594267 254815340 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591983 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33) LTAGTBZSDPMYPZ-UHFFFAOYSA-N 158147 US9024044, 75::US9227949, 75::US9655879, 75 Enteropeptidase Homo sapiens 0.390 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158147&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044976 254815341 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591985 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC1CC1)CC(O)=O InChI=1S/C23H26FN3O5S/c1-23(2,22(31)27(12-19(28)29)11-13-3-4-13)10-15-6-8-18(33-15)21(30)32-17-7-5-14(20(25)26)9-16(17)24/h5-9,13H,3-4,10-12H2,1-2H3,(H3,25,26)(H,28,29) QSMCGKUCUJMHFH-UHFFFAOYSA-N 308540 US9655879, 76 Enteropeptidase Homo sapiens 0.670 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308540&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796604 382364608 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591987 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(=O)NCC(O)=O InChI=1S/C23H27FN4O6S/c1-3-23(4-2,22(33)28-11-18(29)27-12-19(30)31)10-14-6-8-17(35-14)21(32)34-16-7-5-13(20(25)26)9-15(16)24/h5-9H,3-4,10-12H2,1-2H3,(H3,25,26)(H,27,29)(H,28,33)(H,30,31) YCIHRVPQPIJYOG-UHFFFAOYSA-N 158149 BDBM308541::US9024044, 77::US9227949, 77 Enteropeptidase Homo sapiens 0.690 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158149&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 92044978 254815343 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591989 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C24H28FN3O5S.ClH/c1-24(2,23(32)28-15-6-3-13(4-7-15)21(29)30)12-16-8-10-19(34-16)22(31)33-18-9-5-14(20(26)27)11-17(18)25;/h5,8-11,13,15H,3-4,6-7,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30);1H/t13-,15-; SUCPQVSYINREFE-IOJSEOPQSA-N 308542 US9655879, 78 Enteropeptidase Homo sapiens 1.53 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308542&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796601 382364610 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591991 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CC1)C(O)=O InChI=1S/C23H26FN3O5S/c1-3-22(4-2,20(29)27-23(9-10-23)21(30)31)12-14-6-8-17(33-14)19(28)32-16-7-5-13(18(25)26)11-15(16)24/h5-8,11H,3-4,9-10,12H2,1-2H3,(H3,25,26)(H,27,29)(H,30,31) FJLPBYYWEBALPV-UHFFFAOYSA-N 308543 US9655879, 79 Enteropeptidase Homo sapiens 1.12 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308543&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796605 382364611 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591993 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NC1(CCC1)C(O)=O InChI=1S/C24H28FN3O5S/c1-3-23(4-2,21(30)28-24(22(31)32)10-5-11-24)13-15-7-9-18(34-15)20(29)33-17-8-6-14(19(26)27)12-16(17)25/h6-9,12H,3-5,10-11,13H2,1-2H3,(H3,26,27)(H,28,30)(H,31,32) IZBCXOUJPXKGHT-UHFFFAOYSA-N 308544 US9655879, 80 Enteropeptidase Homo sapiens 1.33 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308544&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796606 382364612 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591995 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCc1nnn[nH]1 InChI=1S/C21H24FN7O3S/c1-3-21(4-2,20(31)25-11-17-26-28-29-27-17)10-13-6-8-16(33-13)19(30)32-15-7-5-12(18(23)24)9-14(15)22/h5-9H,3-4,10-11H2,1-2H3,(H3,23,24)(H,25,31)(H,26,27,28,29) LJLCZQKLQRISET-UHFFFAOYSA-N 158153 BDBM308545::US9024044, 81::US9227949, 81 Enteropeptidase Homo sapiens 1.20 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158153&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 90070125 254815347 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591997 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(O)c(c1)C(O)=O InChI=1S/C26H26FN3O6S/c1-3-26(4-2,25(35)30-15-6-8-19(31)17(12-15)23(32)33)13-16-7-10-21(37-16)24(34)36-20-9-5-14(22(28)29)11-18(20)27/h5-12,31H,3-4,13H2,1-2H3,(H3,28,29)(H,30,35)(H,32,33) VTJKUQVDQBWOCA-UHFFFAOYSA-N 308546 US9655879, 82 Enteropeptidase Homo sapiens 3.52 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308546&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796607 382364614 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 591999 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O InChI=1S/C21H24FN3O5S/c1-3-21(4-2,20(29)25-11-17(26)27)10-13-6-8-16(31-13)19(28)30-15-7-5-12(18(23)24)9-14(15)22/h5-9H,3-4,10-11H2,1-2H3,(H3,23,24)(H,25,29)(H,26,27) XTZNPNPXVDSSKQ-UHFFFAOYSA-N 308547 US9655879, 83 Enteropeptidase Homo sapiens 0.720 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308547&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796608 382364615 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592001 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)c1nnn[nH]1 199974 BDBM308548::US9227949, 84 Enteropeptidase Homo sapiens 0.430 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199974&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998723 318589808 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592003 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CCC[C@H](C1)C(O)=O InChI=1S/C24H28FN3O5S.ClH/c1-24(2,23(32)28-15-5-3-4-14(10-15)21(29)30)12-16-7-9-19(34-16)22(31)33-18-8-6-13(20(26)27)11-17(18)25;/h6-9,11,14-15H,3-5,10,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30);1H/t14-,15+;/m1./s1 WMGWJDCQDXSPBX-LIOBNPLQSA-N 308549 US9655879, 85 Enteropeptidase Homo sapiens 0.810 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308549&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796609 382364617 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592005 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1nn[nH]n1)C(O)=O InChI=1S/C23H26FN7O5S.ClH/c1-3-23(4-2,22(35)27-15(20(32)33)10-18-28-30-31-29-18)11-13-6-8-17(37-13)21(34)36-16-7-5-12(19(25)26)9-14(16)24;/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,35)(H,32,33)(H,28,29,30,31);1H/t15-;/m0./s1 HXWXJUXZXQLAFJ-RSAXXLAASA-N 308550 US9655879, 86 Enteropeptidase Homo sapiens 0.240 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308550&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796610 382364618 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592007 CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C17H17FN2O4S/c1-17(2,16(22)23)8-10-4-6-13(25-10)15(21)24-12-5-3-9(14(19)20)7-11(12)18/h3-7H,8H2,1-2H3,(H3,19,20)(H,22,23) NPDVBBRDXJPEMJ-UHFFFAOYSA-N 199977 US9227949, 87::US9655879, 87 Enteropeptidase Homo sapiens 0.390 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199977&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 72700236 318589811 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592009 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC(C1)C(O)=O InChI=1S/C23H26FN3O5S/c1-3-23(4-2,22(31)27-11-14(12-27)20(28)29)10-15-6-8-18(33-15)21(30)32-17-7-5-13(19(25)26)9-16(17)24/h5-9,14H,3-4,10-12H2,1-2H3,(H3,25,26)(H,28,29) GIUBBIQNNZJOCU-UHFFFAOYSA-N 308552 US9655879, 88 Enteropeptidase Homo sapiens 1.000 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308552&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796611 382364620 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592011 CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cccc(c1)S(O)(=O)=O InChI=1S/C25H26FN3O6S2/c1-3-25(4-2,24(31)29-16-6-5-7-18(13-16)37(32,33)34)14-17-9-11-21(36-17)23(30)35-20-10-8-15(22(27)28)12-19(20)26/h5-13H,3-4,14H2,1-2H3,(H3,27,28)(H,29,31)(H,32,33,34) YTPAUABEQNQFGK-UHFFFAOYSA-N 199979 US9227949, 89::US9655879, 89 Enteropeptidase Homo sapiens 0.840 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=199979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=199979&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 117998590 318589813 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592013 Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O InChI=1S/C27H26FN3O7S/c1-3-27(4-2,26(37)31-15-6-8-17(23(32)33)18(12-15)24(34)35)13-16-7-10-21(39-16)25(36)38-20-9-5-14(22(29)30)11-19(20)28/h5-12H,3-4,13H2,1-2H3,(H3,29,30)(H,31,37)(H,32,33)(H,34,35) LUDVRKPPTTXHDS-UHFFFAOYSA-N 308554 US9655879, 90 Enteropeptidase Homo sapiens 0.550 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308554&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796612 382364622 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592015 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1CC[C@@H](C1)C(O)=O InChI=1S/C22H24FN3O5S.ClH/c1-22(2,21(30)26-8-7-13(11-26)19(27)28)10-14-4-6-17(32-14)20(29)31-16-5-3-12(18(24)25)9-15(16)23;/h3-6,9,13H,7-8,10-11H2,1-2H3,(H3,24,25)(H,27,28);1H/t13-;/m0./s1 PPTUCEHTBRKENK-ZOWNYOTGSA-N 308555 US9655879, 91 Enteropeptidase Homo sapiens 0.900 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308555&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796613 382364623 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592017 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](C(O)=O)c1ccc(O)cc1 InChI=1S/C25H24FN3O6S.ClH/c1-25(2,24(34)29-20(22(31)32)13-3-6-15(30)7-4-13)12-16-8-10-19(36-16)23(33)35-18-9-5-14(21(27)28)11-17(18)26;/h3-11,20,30H,12H2,1-2H3,(H3,27,28)(H,29,34)(H,31,32);1H/t20-;/m0./s1 NHHGECCFDYDVDB-BDQAORGHSA-N 308556 US9655879, 92 Enteropeptidase Homo sapiens 0.670 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308556&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796614 382364624 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592019 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H](O)C[C@H]1C(O)=O InChI=1S/C22H24FN3O6S.ClH/c1-22(2,21(31)26-10-12(27)8-15(26)19(28)29)9-13-4-6-17(33-13)20(30)32-16-5-3-11(18(24)25)7-14(16)23;/h3-7,12,15,27H,8-10H2,1-2H3,(H3,24,25)(H,28,29);1H/t12-,15+;/m1./s1 GWIJLLXILSSIGB-YLCXCWDSSA-N 308557 US9655879, 93 Enteropeptidase Homo sapiens 0.300 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308557&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796615 382364625 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 592021 Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H]1CC=CC[C@H]1C(O)=O InChI=1S/C24H26FN3O5S.ClH/c1-24(2,23(32)28-17-6-4-3-5-15(17)21(29)30)12-14-8-10-19(34-14)22(31)33-18-9-7-13(20(26)27)11-16(18)25;/h3-4,7-11,15,17H,5-6,12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30);1H/t15-,17+;/m1./s1 ZJSBEFYNZGPLRB-KALLACGZSA-N 308558 US9655879, 94 Enteropeptidase Homo sapiens 1.30 US Patent 10.7270/Q22Z17KS aid1796235 US9655879 Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T EA Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=308558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=308558&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 137796616 382364626 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207111 CCN(CCC(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C16H17FN4O4S/c1-2-21(6-5-13(22)23)16-20-8-12(26-16)15(24)25-11-4-3-9(14(18)19)7-10(11)17/h3-4,7-8H,2,5-6H2,1H3,(H3,18,19)(H,22,23) FBKHSYTWJJUQGM-UHFFFAOYSA-N 571760 3-((5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoic Acid::US11447480, Example 1 Enteropeptidase Homo sapiens 0.680 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571760&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147469104 473132843 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207112 COC(=O)CCCN(C)C(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C23H29N5O5S/c1-27(11-3-4-19(29)32-2)21(30)16-9-12-28(13-10-16)23-26-14-18(34-23)22(31)33-17-7-5-15(6-8-17)20(24)25/h5-8,14,16H,3-4,9-13H2,1-2H3,(H3,24,25) QIECPWHBWXFGHH-UHFFFAOYSA-N 571761 4-Carbamimidoylphenyl 2-(4-((4-methoxy-4-oxobutyl)(methyl)carbamoyl) piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 31 Enteropeptidase Homo sapiens 17.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571761&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242580 473132844 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207113 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(O)=O)cc1 InChI=1S/C17H18N4O4S/c18-14(19)10-1-3-12(4-2-10)25-16(24)13-9-20-17(26-13)21-7-5-11(6-8-21)15(22)23/h1-4,9,11H,5-8H2,(H3,18,19)(H,22,23) HRNZDDSNGDNAMG-UHFFFAOYSA-N 571762 Tert-butyl 2-bromothiazole-5-carboxylate::US11447480, Example 2 Enteropeptidase Homo sapiens 4.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571762&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681184 473132845 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207114 COC(=O)C(C)(C)CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C23H29N5O5S/c1-23(2,21(31)32-3)13-27-19(29)15-8-10-28(11-9-15)22-26-12-17(34-22)20(30)33-16-6-4-14(5-7-16)18(24)25/h4-7,12,15H,8-11,13H2,1-3H3,(H3,24,25)(H,27,29) NRADLAAXDIOFLF-UHFFFAOYSA-N 571763 4-Carbamimidoylphenyl 2-(4-((3-methoxy-2,2-dimethyl-3-oxopropyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 32 Enteropeptidase Homo sapiens 18.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571763&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681205 473132846 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207115 COC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C18H20N4O4S/c1-25-16(23)12-6-8-22(9-7-12)18-21-10-14(27-18)17(24)26-13-4-2-11(3-5-13)15(19)20/h2-5,10,12H,6-9H2,1H3,(H3,19,20) UHFBZUOFXQOLDM-UHFFFAOYSA-N 571764 4-Carbamimidoylphenyl 2-(4-(methoxycarbonyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 3 Enteropeptidase Homo sapiens 17.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571764&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681200 473132847 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207116 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)NCC(O)=O)cc1 InChI=1S/C19H21N5O5S/c20-16(21)11-1-3-13(4-2-11)29-18(28)14-9-23-19(30-14)24-7-5-12(6-8-24)17(27)22-10-15(25)26/h1-4,9,12H,5-8,10H2,(H3,20,21)(H,22,27)(H,25,26) HFMSFEJXNGLOPU-UHFFFAOYSA-N 571765 (1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)piperidine-4-carbonyl)glycine::US11447480, Example 33 Enteropeptidase Homo sapiens 8.20 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571765&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 158463813 473132848 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207117 COC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C18H19FN4O4S/c1-26-16(24)10-4-6-23(7-5-10)18-22-9-14(28-18)17(25)27-13-3-2-11(15(20)21)8-12(13)19/h2-3,8-10H,4-7H2,1H3,(H3,20,21) VQVLIMWBWWUFJU-UHFFFAOYSA-N 571766 4-Carbamimidoyl-2-fluorophenyl 2-(4-(methoxycarbonyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 4 Enteropeptidase Homo sapiens 0.920 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571766&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681197 473132849 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207118 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)NCCC(O)=O)cc1 InChI=1S/C20H23N5O5S/c21-17(22)12-1-3-14(4-2-12)30-19(29)15-11-24-20(31-15)25-9-6-13(7-10-25)18(28)23-8-5-16(26)27/h1-4,11,13H,5-10H2,(H3,21,22)(H,23,28)(H,26,27) CQLZALRUKOMEHG-UHFFFAOYSA-N 571767 3-(1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxamido)propanoic Acid::US11447480, Example 34 Enteropeptidase Homo sapiens 8.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571767&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 157659682 473132850 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207119 COC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(NC(N)=N)cc1 InChI=1S/C18H21N5O4S/c1-26-15(24)11-6-8-23(9-7-11)18-21-10-14(28-18)16(25)27-13-4-2-12(3-5-13)22-17(19)20/h2-5,10-11H,6-9H2,1H3,(H4,19,20,22) ATUPGUWJQKPHPN-UHFFFAOYSA-N 571768 4-Guanidinophenyl 2-(4-(methoxycarbonyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 5 Enteropeptidase Homo sapiens 510 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571768&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 153407304 473132851 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207120 CN(CCCC(O)=O)C(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H27N5O5S/c1-26(10-2-3-18(28)29)20(30)15-8-11-27(12-9-15)22-25-13-17(33-22)21(31)32-16-6-4-14(5-7-16)19(23)24/h4-7,13,15H,2-3,8-12H2,1H3,(H3,23,24)(H,28,29) IJNODRAQWJUAME-UHFFFAOYSA-N 571769 4-(1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)-N-methylpiperidine-4-carboxamido)butanoic Acid::US11447480, Example 35 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571769&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 158717783 473132852 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207121 NC(=N)Nc1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(O)=O)cc1 InChI=1S/C17H19N5O4S/c18-16(19)21-11-1-3-12(4-2-11)26-15(25)13-9-20-17(27-13)22-7-5-10(6-8-22)14(23)24/h1-4,9-10H,5-8H2,(H,23,24)(H4,18,19,21) NOCYCOVDEPUBFR-UHFFFAOYSA-N 571770 1-(5-((4-Guanidinophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxylic Acid::US11447480, Example 6 Enteropeptidase Homo sapiens 220 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571770&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242131 473132853 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207122 CC(C)(CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C22H27N5O5S/c1-22(2,20(30)31)12-26-18(28)14-7-9-27(10-8-14)21-25-11-16(33-21)19(29)32-15-5-3-13(4-6-15)17(23)24/h3-6,11,14H,7-10,12H2,1-2H3,(H3,23,24)(H,26,28)(H,30,31) BDJUDABBRAYMKT-UHFFFAOYSA-N 571771 3-(1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxamido)-2,2-dimethyl Propanoic Acid::US11447480, Example 36 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571771&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147062212 473132854 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207123 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(O)=O)c(F)c1 InChI=1S/C17H17FN4O4S/c18-11-7-10(14(19)20)1-2-12(11)26-16(25)13-8-21-17(27-13)22-5-3-9(4-6-22)15(23)24/h1-2,7-9H,3-6H2,(H3,19,20)(H,23,24) YBQKZEZXJRWODL-UHFFFAOYSA-N 571772 1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxylic Acid::US11447480, Example 7 Enteropeptidase Homo sapiens 0.600 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571772&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149327375 473132855 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207124 COC(=O)CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H22FN5O5S/c1-30-16(27)10-24-18(28)11-4-6-26(7-5-11)20-25-9-15(32-20)19(29)31-14-3-2-12(17(22)23)8-13(14)21/h2-3,8-9,11H,4-7,10H2,1H3,(H3,22,23)(H,24,28) VCIUDVYOQZGFDJ-UHFFFAOYSA-N 571773 4-Carbamimidoyl-2-fluorophenyl 2-(4-((2-methoxy-2-oxoethyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 37 Enteropeptidase Homo sapiens 1.80 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571773&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242578 473132856 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207125 COC(=O)CCN(C)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C16H18N4O4S/c1-20(8-7-13(21)23-2)16-19-9-12(25-16)15(22)24-11-5-3-10(4-6-11)14(17)18/h3-6,9H,7-8H2,1-2H3,(H3,17,18) KWHYMEHHRLARHF-UHFFFAOYSA-N 571774 4-Carbamimidoylphenyl 2-((3-methoxy-3-oxopropyl)(methyl)amino)thiazole-5-carboxylate::US11447480, Example 8 Enteropeptidase Homo sapiens 28.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571774&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681203 473132857 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207126 COC(=O)CCNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C21H24FN5O5S/c1-31-17(28)4-7-25-19(29)12-5-8-27(9-6-12)21-26-11-16(33-21)20(30)32-15-3-2-13(18(23)24)10-14(15)22/h2-3,10-12H,4-9H2,1H3,(H3,23,24)(H,25,29) RWGNEWAHFQGQNF-UHFFFAOYSA-N 571775 4-Carbamimidoyl-2-fluorophenyl 2-(4-((3-methoxy-3-oxopropyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 38 Enteropeptidase Homo sapiens 2.60 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571775&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242321 473132858 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207127 CN(CCC(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C15H16N4O4S/c1-19(7-6-12(20)21)15-18-8-11(24-15)14(22)23-10-4-2-9(3-5-10)13(16)17/h2-5,8H,6-7H2,1H3,(H3,16,17)(H,20,21) KWBPAGLXNPRUDW-UHFFFAOYSA-N 571776 3-((5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)(methyl)amino)propanoic Acid::US11447480, Example 9 Enteropeptidase Homo sapiens 28.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571776&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 159257422 473132859 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207128 COC(=O)C(C)(C)CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H28FN5O5S/c1-23(2,21(32)33-3)12-28-19(30)13-6-8-29(9-7-13)22-27-11-17(35-22)20(31)34-16-5-4-14(18(25)26)10-15(16)24/h4-5,10-11,13H,6-9,12H2,1-3H3,(H3,25,26)(H,28,30) LGXXSTZTQPHCCS-UHFFFAOYSA-N 571777 4-Carbamimidoyl-2-fluorophenyl 2-(4-((3-methoxy-2,2-dimethyl-3-oxopropyl) carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 39 Enteropeptidase Homo sapiens 2.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571777&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148342526 473132860 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207129 COC(=O)CCNc1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C15H16N4O4S/c1-22-12(20)6-7-18-15-19-8-11(24-15)14(21)23-10-4-2-9(3-5-10)13(16)17/h2-5,8H,6-7H2,1H3,(H3,16,17)(H,18,19) STQHZPRZSWNBSV-UHFFFAOYSA-N 571778 4-Carbamimidoylphenyl 2-((3-methoxy-3-oxopropyl)amino)thiazole-5-carboxylate::US11447480, Example 10 Enteropeptidase Homo sapiens 11.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571778&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681210 473132861 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207130 COc1ccc(NC(=O)C2CCN(CC2)c2ncc(s2)C(=O)Oc2ccc(cc2)C(N)=N)cc1 InChI=1S/C24H25N5O4S/c1-32-18-8-4-17(5-9-18)28-22(30)16-10-12-29(13-11-16)24-27-14-20(34-24)23(31)33-19-6-2-15(3-7-19)21(25)26/h2-9,14,16H,10-13H2,1H3,(H3,25,26)(H,28,30) WMTBHWMFSRZZNF-UHFFFAOYSA-N 571779 4-carbamimidoylphenyl 2-(4-((4-methoxyphenyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 40 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571779&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 161547895 473132862 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207131 COC(=O)CCCN(C)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C17H20N4O4S/c1-21(9-3-4-14(22)24-2)17-20-10-13(26-17)16(23)25-12-7-5-11(6-8-12)15(18)19/h5-8,10H,3-4,9H2,1-2H3,(H3,18,19) ZRFGMILYULUPLG-UHFFFAOYSA-N 571780 4-Carbamimidoylphenyl 2-((4-methoxy-4-oxobutyl)(methyl)amino)thiazole-5-carboxylate::US11447480, Example 11 Enteropeptidase Homo sapiens 21.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571780&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149555702 473132863 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207132 COC(=O)CCCN(C)C(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H28FN5O5S/c1-28(9-3-4-19(30)33-2)21(31)14-7-10-29(11-8-14)23-27-13-18(35-23)22(32)34-17-6-5-15(20(25)26)12-16(17)24/h5-6,12-14H,3-4,7-11H2,1-2H3,(H3,25,26) HJIWOQBOBHAHHQ-UHFFFAOYSA-N 571781 4-Carbamimidoyl-2-fluorophenyl 2-(4-((4-methoxy-4-oxobutyl)(methyl)carbamoyl) piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 41 Enteropeptidase Homo sapiens 1.80 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571781&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242567 473132864 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207133 CCN(CCC(=O)OC)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C17H20N4O4S/c1-3-21(9-8-14(22)24-2)17-20-10-13(26-17)16(23)25-12-6-4-11(5-7-12)15(18)19/h4-7,10H,3,8-9H2,1-2H3,(H3,18,19) RBSVYGSXQFNYSQ-UHFFFAOYSA-N 571782 4-Carbamimidoylphenyl 2-(ethyl(3-methoxy-3-oxopropyl)amino)thiazole-5-carboxylate::US11447480, Example 12 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571782&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149128553 473132865 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207134 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)NCC(O)=O)c(F)c1 InChI=1S/C19H20FN5O5S/c20-12-7-11(16(21)22)1-2-13(12)30-18(29)14-8-24-19(31-14)25-5-3-10(4-6-25)17(28)23-9-15(26)27/h1-2,7-8,10H,3-6,9H2,(H3,21,22)(H,23,28)(H,26,27) UEPHWPHJCUFJPX-UHFFFAOYSA-N 571783 (1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carbonyl)glycine::US11447480, Example 42 Enteropeptidase Homo sapiens 1.000 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571783&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242253 473132866 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207135 NC(=N)c1ccc(OC(=O)c2cnc(NCCC(O)=O)s2)cc1 InChI=1S/C14H14N4O4S/c15-12(16)8-1-3-9(4-2-8)22-13(21)10-7-18-14(23-10)17-6-5-11(19)20/h1-4,7H,5-6H2,(H3,15,16)(H,17,18)(H,19,20) CQCJKZRETQIJSU-UHFFFAOYSA-N 571784 3-((5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)amino)propanoic Acid::US11447480, Example 13 Enteropeptidase Homo sapiens 4.80 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571784&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147269262 473132867 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207136 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)NCCC(O)=O)c(F)c1 InChI=1S/C20H22FN5O5S/c21-13-9-12(17(22)23)1-2-14(13)31-19(30)15-10-25-20(32-15)26-7-4-11(5-8-26)18(29)24-6-3-16(27)28/h1-2,9-11H,3-8H2,(H3,22,23)(H,24,29)(H,27,28) ZZUUALKLOYQVMJ-UHFFFAOYSA-N 571785 3-(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxamido)propanoic Acid::US11447480, Example 43 Enteropeptidase Homo sapiens 1.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571785&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 156064565 473132868 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207137 CCN(CCC(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C16H18N4O4S/c1-2-20(8-7-13(21)22)16-19-9-12(25-16)15(23)24-11-5-3-10(4-6-11)14(17)18/h3-6,9H,2,7-8H2,1H3,(H3,17,18)(H,21,22) YYPPEXOITNWGDU-UHFFFAOYSA-N 571786 3-((5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoic Acid::US11447480, Example 14 Enteropeptidase Homo sapiens 5.10 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571786&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149456249 473132869 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207138 CN(CCCC(O)=O)C(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H26FN5O5S/c1-27(8-2-3-18(29)30)20(31)13-6-9-28(10-7-13)22-26-12-17(34-22)21(32)33-16-5-4-14(19(24)25)11-15(16)23/h4-5,11-13H,2-3,6-10H2,1H3,(H3,24,25)(H,29,30) LEEDGTFVRAMKEB-UHFFFAOYSA-N 571787 4-(1-(5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)-N-methylpiperidine-4-carboxamido)butanoic Acid::US11447480, Example 44 Enteropeptidase Homo sapiens 1.60 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571787&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 159324402 473132870 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207139 CN(CCCC(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C16H18N4O4S/c1-20(8-2-3-13(21)22)16-19-9-12(25-16)15(23)24-11-6-4-10(5-7-11)14(17)18/h4-7,9H,2-3,8H2,1H3,(H3,17,18)(H,21,22) BKYSGUWJDIGFJT-UHFFFAOYSA-N 571788 4-((5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)(methyl)amino)butanoic Acid::US11447480, Example 15 Enteropeptidase Homo sapiens 5.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571788&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147102695 473132871 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207140 CC(C)(CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C22H26FN5O5S/c1-22(2,20(31)32)11-27-18(29)12-5-7-28(8-6-12)21-26-10-16(34-21)19(30)33-15-4-3-13(17(24)25)9-14(15)23/h3-4,9-10,12H,5-8,11H2,1-2H3,(H3,24,25)(H,27,29)(H,31,32) IJELOQAPNNHQFS-UHFFFAOYSA-N 571789 3-(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carboxamido)-2, 2-dimethylpropanoic Acid::US11447480, Example 45 Enteropeptidase Homo sapiens 1.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571789&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146242143 473132872 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207141 COC(=O)C1CCN(C1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C17H18N4O4S/c1-24-15(22)11-6-7-21(9-11)17-20-8-13(26-17)16(23)25-12-4-2-10(3-5-12)14(18)19/h2-5,8,11H,6-7,9H2,1H3,(H3,18,19) LQSFJKSGAVGNAM-UHFFFAOYSA-N 571790 4-Carbamimidoylphenyl 2-(3-(methoxycarbonyl)pyrrolidin-1-yl)thiazole-5-carboxylate::US11447480, Example 16 Enteropeptidase Homo sapiens 19.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571790&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148395024 473132873 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207142 CCN(CCC(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C28H38FN5O7S/c1-8-34(26-32-15-20(42-26)25(38)39-19-10-9-16(23(30)31)13-17(19)29)12-11-21(35)33-18(24(37)41-28(5,6)7)14-22(36)40-27(2,3)4/h9-10,13,15,18H,8,11-12,14H2,1-7H3,(H3,30,31)(H,33,35)/t18-/m0/s1 SHXIZFROWXUVHF-SFHVURJKSA-N 571791 Di-tert-butyl(3-((5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoyl)-L-aspartate::US11447480, Example 46 Enteropeptidase Homo sapiens 40.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571791&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681213 473132874 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207143 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(C2)C(O)=O)cc1 InChI=1S/C16H16N4O4S/c17-13(18)9-1-3-11(4-2-9)24-15(23)12-7-19-16(25-12)20-6-5-10(8-20)14(21)22/h1-4,7,10H,5-6,8H2,(H3,17,18)(H,21,22) RYVOXYRASYCBGN-UHFFFAOYSA-N 571792 1-(5-((4-Carbamimidoylphenoxy)carbonyl)thiazol-2-yl)pyrrolidine-3-carboxylic Acid::US11447480, Example 17 Enteropeptidase Homo sapiens 5.40 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571792&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 151802204 473132875 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207144 CCN(CCC(=O)N[C@@H](CC(O)=O)C(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H22FN5O7S/c1-2-26(6-5-15(27)25-12(18(30)31)8-16(28)29)20-24-9-14(34-20)19(32)33-13-4-3-10(17(22)23)7-11(13)21/h3-4,7,9,12H,2,5-6,8H2,1H3,(H3,22,23)(H,25,27)(H,28,29)(H,30,31)/t12-/m0/s1 SJEXUAFYMWYCHM-LBPRGKRZSA-N 571793 (3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoyl)-L-aspartic Acid::US11447480, Example 47 Enteropeptidase Homo sapiens 0.520 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571793&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146853876 473132876 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207145 COC(=O)C(C)(C)CN(C)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C18H22N4O4S/c1-18(2,16(24)25-4)10-22(3)17-21-9-13(27-17)15(23)26-12-7-5-11(6-8-12)14(19)20/h5-9H,10H2,1-4H3,(H3,19,20) ZGECRJKCQKWHDV-UHFFFAOYSA-N 571794 4-Carbamimidoylphenyl 2-((3-methoxy-2,2-dimethyl-3-oxopropyl)(methyl) amino)thiazole-5-carboxylate::US11447480, Example 18 Enteropeptidase Homo sapiens 8.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571794&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681196 473132877 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207146 CCN(CCC(=O)N[C@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C29H40FN5O7S/c1-8-35(27-33-16-21(43-27)26(39)40-20-11-9-17(24(31)32)15-18(20)30)14-13-22(36)34-19(25(38)42-29(5,6)7)10-12-23(37)41-28(2,3)4/h9,11,15-16,19H,8,10,12-14H2,1-7H3,(H3,31,32)(H,34,36)/t19-/m1/s1 PATWSLRDDGKDLE-LJQANCHMSA-N 571795 Di-tert-butyl (3-((5-((4-carbamimidoyl)-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoyl)-D-glutamate::US11447480, Example 48 Enteropeptidase Homo sapiens 37.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571795&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 160152869 473132878 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207147 CN(CC(C)(C)C(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C17H20N4O4S/c1-17(2,15(23)24)9-21(3)16-20-8-12(26-16)14(22)25-11-6-4-10(5-7-11)13(18)19/h4-8H,9H2,1-3H3,(H3,18,19)(H,23,24) ZBZQIWWBPVWFMP-UHFFFAOYSA-N 571796 3-((5-((4-carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)(methyl)amino)-2,2-dimethylpropanoic Acid::US11447480, Example 19 Enteropeptidase Homo sapiens 4.80 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571796&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 162078305 473132879 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207148 CCN(CCC(=O)N[C@H](CCC(O)=O)C(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C21H24FN5O7S/c1-2-27(8-7-16(28)26-13(19(31)32)4-6-17(29)30)21-25-10-15(35-21)20(33)34-14-5-3-11(18(23)24)9-12(14)22/h3,5,9-10,13H,2,4,6-8H2,1H3,(H3,23,24)(H,26,28)(H,29,30)(H,31,32)/t13-/m1/s1 WKRDIRRBYUJLLA-CYBMUJFWSA-N 571797 (3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanoyl)-D-glutamic Acid::US11447480, Example 49 Enteropeptidase Homo sapiens 0.570 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571797&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681185 473132880 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207149 CCN(CCC(=O)OC)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C17H19FN4O4S/c1-3-22(7-6-14(23)25-2)17-21-9-13(27-17)16(24)26-12-5-4-10(15(19)20)8-11(12)18/h4-5,8-9H,3,6-7H2,1-2H3,(H3,19,20) IRHDGAFGZZOCTR-UHFFFAOYSA-N 571798 4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-3-oxopropyl)amino) thiazole-5-carboxylate::US11447480, Example 20 Enteropeptidase Homo sapiens 2.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571798&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147970753 473132881 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207150 CCN(CCC(=O)Nc1ccc(cc1)C(=O)OC)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C24H24FN5O5S/c1-3-30(11-10-20(31)29-16-7-4-14(5-8-16)22(32)34-2)24-28-13-19(36-24)23(33)35-18-9-6-15(21(26)27)12-17(18)25/h4-9,12-13H,3,10-11H2,1-2H3,(H3,26,27)(H,29,31) KOCDHAHMJJJVGG-UHFFFAOYSA-N 571799 4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-((4-(methoxycarbonyl)phenyl)amino)-3-oxopropyl)amino)thiazole-5-carboxylate::US11447480, Example 50 Enteropeptidase Homo sapiens 14.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571799&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681180 473132882 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207151 COC(=O)CCCN(C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C17H19FN4O4S/c1-22(7-3-4-14(23)25-2)17-21-9-13(27-17)16(24)26-12-6-5-10(15(19)20)8-11(12)18/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20) GOTPHPLDSBCXCZ-UHFFFAOYSA-N 571800 4-Carbamimidoyl-2-fluorophenyl 2-((4-methoxy-4-oxobutyl)(methyl)amino)thiazole-5-carboxylate::US11447480, Example 21 Enteropeptidase Homo sapiens 3.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571800&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147679164 473132883 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207152 CCN(CCC(=O)Nc1cccc(c1)C(=O)OC)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C24H24FN5O5S/c1-3-30(10-9-20(31)29-16-6-4-5-15(11-16)22(32)34-2)24-28-13-19(36-24)23(33)35-18-8-7-14(21(26)27)12-17(18)25/h4-8,11-13H,3,9-10H2,1-2H3,(H3,26,27)(H,29,31) NCHSXCILLIXXSN-UHFFFAOYSA-N 571801 4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-((3-(methoxycarbonyl)phenyl)amino)-3-oxopropyl) amino)thiazole-5-carboxylate::US11447480, Example 51 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571801&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681202 473132884 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207153 CN(CCCC(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C16H17FN4O4S/c1-21(6-2-3-13(22)23)16-20-8-12(26-16)15(24)25-11-5-4-9(14(18)19)7-10(11)17/h4-5,7-8H,2-3,6H2,1H3,(H3,18,19)(H,22,23) OYFZCFIMLBQBAO-UHFFFAOYSA-N 571802 4-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(methyl)amino)butanoic Acid::US11447480, Example 22 Enteropeptidase Homo sapiens 0.570 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571802&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148855290 473132885 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207154 CCN(CCC(=O)Nc1ccc(cc1)C(=O)OC(C)(C)C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C27H30FN5O5S/c1-5-33(13-12-22(34)32-18-9-6-16(7-10-18)24(35)38-27(2,3)4)26-31-15-21(39-26)25(36)37-20-11-8-17(23(29)30)14-19(20)28/h6-11,14-15H,5,12-13H2,1-4H3,(H3,29,30)(H,32,34) FNSFFWXHTJLULW-UHFFFAOYSA-N 571803 4-Carbamimidoyl-2-fluorophenyl 2-((3-((4-(tert-butoxycarbonyl)phenyl)amino)-3-oxopropyl)(ethyl)amino)thiazole-5-carboxylate::US11447480, Example 52 Enteropeptidase Homo sapiens 82.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571803&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681198 473132886 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207155 CCN(CCC(=O)Nc1cccc(c1)C(=O)OC(C)(C)C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C27H30FN5O5S/c1-5-33(12-11-22(34)32-18-8-6-7-17(13-18)24(35)38-27(2,3)4)26-31-15-21(39-26)25(36)37-20-10-9-16(23(29)30)14-19(20)28/h6-10,13-15H,5,11-12H2,1-4H3,(H3,29,30)(H,32,34) GOPOXCYTKVLGFQ-UHFFFAOYSA-N 571804 4-Carbamimidoyl-2-fluorophenyl 2-((tert-butoxycarbonyl)phenyl)amino)-3-oxopropyl)(ethyl)amino)thiazole-5-carboxylate::US11447480, Example 53 Enteropeptidase Homo sapiens 12.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571804&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 158319016 473132887 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207156 COC(=O)C(C)(C)CNc1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C17H20N4O4S/c1-17(2,15(23)24-3)9-21-16-20-8-12(26-16)14(22)25-11-6-4-10(5-7-11)13(18)19/h4-8H,9H2,1-3H3,(H3,18,19)(H,20,21) YUYWPYYAMQYRLI-UHFFFAOYSA-N 571805 4-Carbamimidoylphenyl 2-((3-methoxy-2,2-dimethyl-3-oxopropyl)amino)thiazole-5-carboxylate::US11447480, Example 24 Enteropeptidase Homo sapiens 8.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571805&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149430568 473132888 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207157 CCN(CCC(=O)Nc1cccc(c1)C(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H22FN5O5S/c1-2-29(9-8-19(30)28-15-5-3-4-14(10-15)21(31)32)23-27-12-18(35-23)22(33)34-17-7-6-13(20(25)26)11-16(17)24/h3-7,10-12H,2,8-9H2,1H3,(H3,25,26)(H,28,30)(H,31,32) HDXOEFQPNPJDRN-UHFFFAOYSA-N 571806 3-(3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanamido)benzoic Acid::US11447480, Example 54 Enteropeptidase Homo sapiens 2.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571806&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 150401770 473132889 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207158 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H23N5O7S/c22-17(23)11-1-3-13(4-2-11)33-20(32)15-10-24-21(34-15)26-7-5-12(6-8-26)18(29)25-14(19(30)31)9-16(27)28/h1-4,10,12,14H,5-9H2,(H3,22,23)(H,25,29)(H,27,28)(H,30,31)/t14-/m0/s1 MSPBXGXHQIAMCD-AWEZNQCLSA-N 571807 (1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2-yl)piperidine-4-carbonyl)-L-aspartic Acid::US11447480, Example 25 Enteropeptidase Homo sapiens 4.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571807&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148543249 473132890 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207159 CCN(CCC(=O)Nc1ccc(cc1)C(O)=O)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H22FN5O5S/c1-2-29(10-9-19(30)28-15-6-3-13(4-7-15)21(31)32)23-27-12-18(35-23)22(33)34-17-8-5-14(20(25)26)11-16(17)24/h3-8,11-12H,2,9-10H2,1H3,(H3,25,26)(H,28,30)(H,31,32) CMLMZNDZTHYVNE-UHFFFAOYSA-N 571808 4-(3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)(ethyl)amino)propanamido)benzoic Acid::US11447480, Example 55 Enteropeptidase Homo sapiens 8.20 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571808&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147249782 473132891 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207160 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)N[C@@H](CC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)c(F)c1 InChI=1S/C35H34FN5O7S/c36-26-17-25(31(37)38)11-12-28(26)48-34(45)29-19-39-35(49-29)41-15-13-24(14-16-41)32(43)40-27(33(44)47-21-23-9-5-2-6-10-23)18-30(42)46-20-22-7-3-1-4-8-22/h1-12,17,19,24,27H,13-16,18,20-21H2,(H3,37,38)(H,40,43)/t27-/m0/s1 SDNLBFKDMVROCK-MHZLTWQESA-N 571809 (1-(5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)thiazol-2-yl)piperidine-4-carbonyl)-L-aspartate::US11447480, Example 26 Enteropeptidase Homo sapiens 8.20 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571809&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146828411 473132892 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207161 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)C(=O)Nc2ccccc2)cc1 InChI=1S/C23H23N5O3S/c24-20(25)15-6-8-18(9-7-15)31-22(30)19-14-26-23(32-19)28-12-10-16(11-13-28)21(29)27-17-4-2-1-3-5-17/h1-9,14,16H,10-13H2,(H3,24,25)(H,27,29) XIKPCTCDGSWJTM-UHFFFAOYSA-N 571810 4-Carbamimidoylphenyl 2-(4-(phenylcarbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 27 Enteropeptidase Homo sapiens 12.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571810&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149220856 473132893 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207162 NC(=N)c1ccc(OC(=O)c2cnc(s2)N2CCC(CC2)NC(=O)c2ccccc2)cc1 InChI=1S/C23H23N5O3S/c24-20(25)15-6-8-18(9-7-15)31-22(30)19-14-26-23(32-19)28-12-10-17(11-13-28)27-21(29)16-4-2-1-3-5-16/h1-9,14,17H,10-13H2,(H3,24,25)(H,27,29) FWTYYNQAWVINLE-UHFFFAOYSA-N 571811 4-Carbamimidoylphenyl 2-(4-benzamidopiperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 28 Enteropeptidase Homo sapiens 6.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571811&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147582899 473132894 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207163 COC(=O)CNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C20H23N5O5S/c1-29-16(26)11-23-18(27)13-6-8-25(9-7-13)20-24-10-15(31-20)19(28)30-14-4-2-12(3-5-14)17(21)22/h2-5,10,13H,6-9,11H2,1H3,(H3,21,22)(H,23,27) OZYOFGTYEHRWHD-UHFFFAOYSA-N 571812 4-Carbamimidoylphenyl 2-(4-((2-methoxy-2-oxoethyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 29 Enteropeptidase Homo sapiens 18.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571812&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148864510 473132895 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207164 COC(=O)CCNC(=O)C1CCN(CC1)c1ncc(s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H25N5O5S/c1-30-17(27)6-9-24-19(28)14-7-10-26(11-8-14)21-25-12-16(32-21)20(29)31-15-4-2-13(3-5-15)18(22)23/h2-5,12,14H,6-11H2,1H3,(H3,22,23)(H,24,28) OVRYEIBSHZNFCZ-UHFFFAOYSA-N 571813 4-Carbamimidoylphenyl 2-(4-((3-methoxy-3-oxopropyl)carbamoyl)piperidin-1-yl)thiazole-5-carboxylate::US11447480, Example 30 Enteropeptidase Homo sapiens 18.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571813&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681211 473132896 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207165 CC(C)(CNc1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O InChI=1S/C20H19FN4O4S/c1-20(2,18(27)28)9-24-19-25-13-5-3-11(8-15(13)30-19)17(26)29-14-6-4-10(16(22)23)7-12(14)21/h3-8H,9H2,1-2H3,(H3,22,23)(H,24,25)(H,27,28) RHVPYLWOKAXTGG-UHFFFAOYSA-N 571814 3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)benzo[d]thiazol-2-yl)amino)-2,2-dimethylpropanoic Acid::US11447480, Example 56 Enteropeptidase Homo sapiens 0.590 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571814&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149141449 473132897 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207166 CN(CCCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H19FN4O4S/c1-25(8-2-3-17(26)27)20-24-14-6-4-12(10-16(14)30-20)19(28)29-15-7-5-11(18(22)23)9-13(15)21/h4-7,9-10H,2-3,8H2,1H3,(H3,22,23)(H,26,27) MEYRAMNJVBQDRK-UHFFFAOYSA-N 571815 4-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)benzo[d]thiazol-2-yl)(methyl)amino)butanoic Acid::US11447480, Example 76 Enteropeptidase Homo sapiens 0.570 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571815&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148471057 473132898 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207167 COC(=O)C1CCN(CC1)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H22N4O4S/c1-29-20(27)14-8-10-26(11-9-14)22-25-17-7-4-15(12-18(17)31-22)21(28)30-16-5-2-13(3-6-16)19(23)24/h2-7,12,14H,8-11H2,1H3,(H3,23,24) JEGXOBHQRHHOSQ-UHFFFAOYSA-N 571816 4-Carbamimidoylphenyl 2-(4-(methoxycarbonyl)piperidin-1-yl)benzo[d]thiazole-6-carboxylate::US11447480, Example 57 Enteropeptidase Homo sapiens 13.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571816&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681183 473132899 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207168 CN(CCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C19H17FN4O4S/c1-24(7-6-16(25)26)19-23-13-4-2-11(9-15(13)29-19)18(27)28-14-5-3-10(17(21)22)8-12(14)20/h2-5,8-9H,6-7H2,1H3,(H3,21,22)(H,25,26) TZDVUEKRAZVVQW-UHFFFAOYSA-N 571817 3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)benzo[d]thiazol-2-yl)(methyl) Amino)propanoic Acid::US11447480, Example 77 Enteropeptidase Homo sapiens 0.570 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571817&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 151963491 473132900 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207169 NC(=N)c1ccc(OC(=O)c2ccc3nc(sc3c2)N2CCC(CC2)C(O)=O)cc1 InChI=1S/C21H20N4O4S/c22-18(23)12-1-4-15(5-2-12)29-20(28)14-3-6-16-17(11-14)30-21(24-16)25-9-7-13(8-10-25)19(26)27/h1-6,11,13H,7-10H2,(H3,22,23)(H,26,27) KEPRJUGYSFELJA-UHFFFAOYSA-N 571818 1-(6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)piperidine-4-carboxylic Acid::US11447480, Example 58 Enteropeptidase Homo sapiens 7.40 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571818&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681206 473132901 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207170 COC(=O)CCNc1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C19H18N4O4S/c1-26-16(24)8-9-22-19-23-14-7-4-12(10-15(14)28-19)18(25)27-13-5-2-11(3-6-13)17(20)21/h2-7,10H,8-9H2,1H3,(H3,20,21)(H,22,23) GEAVYWVKSDPYSR-UHFFFAOYSA-N 571819 4-Carbamimidoylphenyl 2-((3-methoxy-3-oxopropyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 59 Enteropeptidase Homo sapiens 14.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571819&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681209 473132902 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207171 CCN(CCC(=O)OC)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H22N4O4S/c1-3-25(11-10-18(26)28-2)21-24-16-9-6-14(12-17(16)30-21)20(27)29-15-7-4-13(5-8-15)19(22)23/h4-9,12H,3,10-11H2,1-2H3,(H3,22,23) PZSKNYJVWUFRBS-UHFFFAOYSA-N 571820 4-Carbamimidoylphenyl 2-((3-methoxy-3-oxopropyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 60::US11447480, Example 61 Enteropeptidase Homo sapiens 10.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571820&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681189 473132903 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207172 NC(=N)c1ccc(OC(=O)c2ccc3nc(sc3c2)N2CCC(CC2)C(=O)Nc2ccccc2)cc1 InChI=1S/C27H25N5O3S/c28-24(29)17-6-9-21(10-7-17)35-26(34)19-8-11-22-23(16-19)36-27(31-22)32-14-12-18(13-15-32)25(33)30-20-4-2-1-3-5-20/h1-11,16,18H,12-15H2,(H3,28,29)(H,30,33) DPUARPWQDFCVHO-UHFFFAOYSA-N 571821 4-Carbamimidoylphenyl 2-(4-(phenylcarbamoyl)piperidin-1-yl)benzo[d]thiazole-6-carboxylate::US11447480, Example 80 Enteropeptidase Homo sapiens 23.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571821&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681190 473132904 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207173 CCN(CCC(=O)OC)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H22N4O4S/c1-3-25(11-10-18(26)28-2)21-24-16-9-6-14(12-17(16)30-21)20(27)29-15-7-4-13(5-8-15)19(22)23/h4-9,12H,3,10-11H2,1-2H3,(H3,22,23) PZSKNYJVWUFRBS-UHFFFAOYSA-N 571820 4-Carbamimidoylphenyl 2-((3-methoxy-3-oxopropyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 60::US11447480, Example 61 Enteropeptidase Homo sapiens 10.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571820&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681189 473132903 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207174 CN(CCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C19H18N4O4S/c1-23(9-8-16(24)25)19-22-14-7-4-12(10-15(14)28-19)18(26)27-13-5-2-11(3-6-13)17(20)21/h2-7,10H,8-9H2,1H3,(H3,20,21)(H,24,25) JZRYBOMJQVTDBN-UHFFFAOYSA-N 571823 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)(methyl)amino)propanoic Acid::US11447480, Example 62 Enteropeptidase Homo sapiens 4.30 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571823&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 150770232 473132905 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207175 NC(=N)c1ccc(OC(=O)c2ccc3nc(sc3c2)N2CCC(CC2)NC(=O)c2ccccc2)c(F)c1 InChI=1S/C27H24FN5O3S/c28-20-14-17(24(29)30)7-9-22(20)36-26(35)18-6-8-21-23(15-18)37-27(32-21)33-12-10-19(11-13-33)31-25(34)16-4-2-1-3-5-16/h1-9,14-15,19H,10-13H2,(H3,29,30)(H,31,34) BBIOJFKWSBVMHI-UHFFFAOYSA-N 571824 4-Carbamimidoyl-2-fluorophenyl 2-(4-benzoamidopiperidin-1-yl)benzo[d]thiazole-6-carboxylate::US11447480, Example 82 Enteropeptidase Homo sapiens 1.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571824&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681191 473132906 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207176 COC(=O)CCCN(C)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H22N4O4S/c1-25(11-3-4-18(26)28-2)21-24-16-10-7-14(12-17(16)30-21)20(27)29-15-8-5-13(6-9-15)19(22)23/h5-10,12H,3-4,11H2,1-2H3,(H3,22,23) KCQHNCQKNOHNMH-UHFFFAOYSA-N 571825 4-Carbamimidoylphenyl 2-((4-methoxy-4-oxobutyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 63 Enteropeptidase Homo sapiens 13.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571825&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681181 473132907 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207177 NC(=N)c1ccc(OC(=O)c2ccc3nc(sc3c2)N2CCC(CC2)NC(=O)c2ccccc2)cc1 InChI=1S/C27H25N5O3S/c28-24(29)17-6-9-21(10-7-17)35-26(34)19-8-11-22-23(16-19)36-27(31-22)32-14-12-20(13-15-32)30-25(33)18-4-2-1-3-5-18/h1-11,16,20H,12-15H2,(H3,28,29)(H,30,33) ASGAYALDMPWJHB-UHFFFAOYSA-N 571826 4-Carbamimidoylphenyl 2-(4-benzoamidopiperidin-1-yl)benzo[d]thiazole-6-carboxylate::US11447480, Example 83 Enteropeptidase Homo sapiens 9.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571826&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681194 473132908 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207178 CN(CCCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C20H20N4O4S/c1-24(10-2-3-17(25)26)20-23-15-9-6-13(11-16(15)29-20)19(27)28-14-7-4-12(5-8-14)18(21)22/h4-9,11H,2-3,10H2,1H3,(H3,21,22)(H,25,26) DVUHHNIHKAUTAS-UHFFFAOYSA-N 571827 4-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)(methyl)amino)butanoic Acid::US11447480, Example 64 Enteropeptidase Homo sapiens 6.40 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571827&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681199 473132909 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207179 CCN(CCC(=O)OC)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C21H21FN4O4S/c1-3-26(9-8-18(27)29-2)21-25-15-6-4-13(11-17(15)31-21)20(28)30-16-7-5-12(19(23)24)10-14(16)22/h4-7,10-11H,3,8-9H2,1-2H3,(H3,23,24) IVRPHNGYWLVRJE-UHFFFAOYSA-N 571828 4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-3-oxopropyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 84 Enteropeptidase Homo sapiens 2.20 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571828&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147994282 473132910 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207180 NC(=N)c1ccc(OC(=O)c2ccc3nc(NCCC(O)=O)sc3c2)cc1 InChI=1S/C18H16N4O4S/c19-16(20)10-1-4-12(5-2-10)26-17(25)11-3-6-13-14(9-11)27-18(22-13)21-8-7-15(23)24/h1-6,9H,7-8H2,(H3,19,20)(H,21,22)(H,23,24) XTANSYYBVJONPV-UHFFFAOYSA-N 571829 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)amino)propanoic Acid::US11447480, Example 65 Enteropeptidase Homo sapiens 5.70 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571829&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 152448830 473132911 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207181 CCN(CCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H19FN4O4S/c1-2-25(8-7-17(26)27)20-24-14-5-3-12(10-16(14)30-20)19(28)29-15-6-4-11(18(22)23)9-13(15)21/h3-6,9-10H,2,7-8H2,1H3,(H3,22,23)(H,26,27) YFOZKONHOLGXRH-UHFFFAOYSA-N 571830 3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)benzo[d]thiazol-2-yl)(ethyl)amino)propanoic Acid::US11447480, Example 85 Enteropeptidase Homo sapiens 0.550 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571830&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149348759 473132912 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207182 CCN(CCC(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C20H20N4O4S/c1-2-24(10-9-17(25)26)20-23-15-8-5-13(11-16(15)29-20)19(27)28-14-6-3-12(4-7-14)18(21)22/h3-8,11H,2,9-10H2,1H3,(H3,21,22)(H,25,26) KOBGGASTSYYCNM-UHFFFAOYSA-N 571831 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)(ethyl)amino)propanoic Acid::US11447480, Example 66 Enteropeptidase Homo sapiens 4.80 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571831&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 150841392 473132913 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207183 CN(CC(C)(C)C(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H22N4O4S/c1-21(2,19(27)28)11-25(3)20-24-15-9-6-13(10-16(15)30-20)18(26)29-14-7-4-12(5-8-14)17(22)23/h4-10H,11H2,1-3H3,(H3,22,23)(H,27,28) FQJKXGSRGBERJU-UHFFFAOYSA-N 571832 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)(methyl)amino)-2,2-dimethylpropanoic Acid::US11447480, Example 86 Enteropeptidase Homo sapiens 10.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571832&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147548867 473132914 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207184 COC(=O)C(C)(C)CNc1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C21H22N4O4S/c1-21(2,19(27)28-3)11-24-20-25-15-9-6-13(10-16(15)30-20)18(26)29-14-7-4-12(5-8-14)17(22)23/h4-10H,11H2,1-3H3,(H3,22,23)(H,24,25) CXLJZDSMQYTCJG-UHFFFAOYSA-N 571833 4-Carbamimidoylphenyl 2-((3-methoxy-2,2-dimethyl-3-oxopropyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 67 Enteropeptidase Homo sapiens 19.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571833&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681193 473132915 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207185 CCn1c2ccc(cc2s\c1=N/CC(C)(C)C(=O)OC)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H25FN4O4S/c1-5-28-16-8-6-14(20(29)32-17-9-7-13(19(25)26)10-15(17)24)11-18(16)33-22(28)27-12-23(2,3)21(30)31-4/h6-11H,5,12H2,1-4H3,(H3,25,26)/b27-22- DYHUXWPWZVNOHM-QYQHSDTDSA-N 571834 4-Carbamimidoyl-2-fluorophenyl (Z)-3-ethyl-2-((3-methoxy-2,2-dimethyl-3-oxopropyl)imino)-2,3-dihydrobenzo[d]thiazole-6-carboxylate::US11447480, Example 87 Enteropeptidase Homo sapiens 4.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571834&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 147452403 473132916 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207186 COC(=O)C(C)(C)CN(C)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H24N4O4S/c1-22(2,20(28)29-4)12-26(3)21-25-16-10-7-14(11-17(16)31-21)19(27)30-15-8-5-13(6-9-15)18(23)24/h5-11H,12H2,1-4H3,(H3,23,24) JISONMFIUAWROY-UHFFFAOYSA-N 571835 4-Carbamimidoylphenyl 2-((3-methoxy-2,2-dimethyl-3-oxopropyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 68 Enteropeptidase Homo sapiens 6.00 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571835&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681208 473132917 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207187 CCn1c2ccc(cc2s\c1=N/CC(C)(C)C(O)=O)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H23FN4O4S/c1-4-27-15-7-5-13(10-17(15)32-21(27)26-11-22(2,3)20(29)30)19(28)31-16-8-6-12(18(24)25)9-14(16)23/h5-10H,4,11H2,1-3H3,(H3,24,25)(H,29,30)/b26-21- SGPPNKFJQBPHBP-QLYXXIJNSA-N 571836 (Z)-3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)-3-ethylbenzo[d]thiazole-2(3H)-ylidine)amino)-2,2-dimethylpropanoic Acid::US11447480, Example 88 Enteropeptidase Homo sapiens 0.160 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571836&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146843550 473132918 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207188 CCN(CC(C)(C)C(=O)OC)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C23H26N4O4S/c1-5-27(13-23(2,3)21(29)30-4)22-26-17-11-8-15(12-18(17)32-22)20(28)31-16-9-6-14(7-10-16)19(24)25/h6-12H,5,13H2,1-4H3,(H3,24,25) BKQYLYAIOFKTAN-UHFFFAOYSA-N 571837 4-Carbamimidoylphenyl 2-(ethyl(3-methoxy-2,2-dimethyl-3-oxopropyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 69 Enteropeptidase Homo sapiens 21.0 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571837&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681188 473132919 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207189 CCN(CC(C)(C)C(=O)OC)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C23H25FN4O4S/c1-5-28(12-23(2,3)21(30)31-4)22-27-16-8-6-14(11-18(16)33-22)20(29)32-17-9-7-13(19(25)26)10-15(17)24/h6-11H,5,12H2,1-4H3,(H3,25,26) ZUFSPRICYDWKPO-UHFFFAOYSA-N 571838 4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-2,2-dimethyl-3-oxopropyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 70 Enteropeptidase Homo sapiens 3.50 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571838&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681182 473132920 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207190 COC(=O)CCCN(C)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C21H21FN4O4S/c1-26(9-3-4-18(27)29-2)21-25-15-7-5-13(11-17(15)31-21)20(28)30-16-8-6-12(19(23)24)10-14(16)22/h5-8,10-11H,3-4,9H2,1-2H3,(H3,23,24) VBMFYRBREYYNDR-UHFFFAOYSA-N 571839 4-Carbamimidoyl-2-fluorophenyl 2-((4-methoxy-4-oxobutyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 71 Enteropeptidase Homo sapiens 1.10 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571839&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681207 473132921 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207191 COC(=O)CCN(C)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C20H19FN4O4S/c1-25(8-7-17(26)28-2)20-24-14-5-3-12(10-16(14)30-20)19(27)29-15-6-4-11(18(22)23)9-13(15)21/h3-6,9-10H,7-8H2,1-2H3,(H3,22,23) HEODTPOWBYMGQV-UHFFFAOYSA-N 571840 4-Carbamimidoyl-2-fluorophenyl 2-((3-methoxy-3-oxopropyl)(methyl)amino)benzo[d]thiazole-6-carboxylate::US11447480, Example 72 Enteropeptidase Homo sapiens 1.30 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571840&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 155681187 473132922 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207192 CC(C)(CNc1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N)C(O)=O InChI=1S/C20H20N4O4S/c1-20(2,18(26)27)10-23-19-24-14-8-5-12(9-15(14)29-19)17(25)28-13-6-3-11(4-7-13)16(21)22/h3-9H,10H2,1-2H3,(H3,21,22)(H,23,24)(H,26,27) WYHQBWWGBALXHE-UHFFFAOYSA-N 571841 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)amino)-2,2-dimethylpropanoic Acid::US11447480, Example 73 Enteropeptidase Homo sapiens 0.890 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571841&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 149166978 473132923 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207193 CCN(CC(C)(C)C(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1)C(N)=N InChI=1S/C22H24N4O4S/c1-4-26(12-22(2,3)20(28)29)21-25-16-10-7-14(11-17(16)31-21)19(27)30-15-8-5-13(6-9-15)18(23)24/h5-11H,4,12H2,1-3H3,(H3,23,24)(H,28,29) RIIZFELQTNRKKA-UHFFFAOYSA-N 571842 3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]thiazol-2-yl)(ethyl) Amino)-2,2-dimethylpropanoic Acid::US11447480, Example 74 Enteropeptidase Homo sapiens 8.90 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571842&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 146732539 473132924 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 1207194 CCN(CC(C)(C)C(O)=O)c1nc2ccc(cc2s1)C(=O)Oc1ccc(cc1F)C(N)=N InChI=1S/C22H23FN4O4S/c1-4-27(11-22(2,3)20(29)30)21-26-15-7-5-13(10-17(15)32-21)19(28)31-16-8-6-12(18(24)25)9-14(16)23/h5-10H,4,11H2,1-3H3,(H3,24,25)(H,29,30) JXWLQVWYQVISCV-UHFFFAOYSA-N 571843 3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)benzo[d]thiazol-2-yl)(ethyl)amino)-2,2-dimethyl Propanoic Acid::US11447480, Example 75 Enteropeptidase Homo sapiens 0.700 US Patent 10.7270/Q2WD43TB aid1806819 US11447480 Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J LG CHEM, LTD. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=571843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=571843&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 148146186 473132925 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476646 Cl.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C20H20N4O7.ClH/c21-20(22)23-13-5-3-12(4-6-13)19(30)31-14-7-1-11(2-8-14)9-16(25)24-15(18(28)29)10-17(26)27;/h1-8,15H,9-10H2,(H,24,25)(H,26,27)(H,28,29)(H4,21,22,23);1H/t15-;/m0./s1 FLLBWNKVJUZVQT-RSAXXLAASA-N 50595337 CHEMBL5195621 Enteropeptidase Homo sapiens 94 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595337&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168289255 482606189 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476647 Cl.Cc1cc(OC(=O)c2ccc(NC(N)=N)cc2)no1 InChI=1S/C12H12N4O3.ClH/c1-7-6-10(16-19-7)18-11(17)8-2-4-9(5-3-8)15-12(13)14;/h2-6H,1H3,(H4,13,14,15);1H LMVIONPUKHVJBQ-UHFFFAOYSA-N 50595338 CHEMBL5190122 Enteropeptidase Homo sapiens 1500 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595338&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168283960 482606190 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476648 CS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccccc1 InChI=1S/C14H13N3O2.CH4O3S/c15-14(16)17-11-8-6-10(7-9-11)13(18)19-12-4-2-1-3-5-12;1-5(2,3)4/h1-9H,(H4,15,16,17);1H3,(H,2,3,4) KSPAQJJGAABPRL-UHFFFAOYSA-N 50595339 CHEMBL5205880 Enteropeptidase Homo sapiens 5600 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595339&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 159228495 482606191 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476649 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)NCC(O)=O)cc1 InChI=1S/C18H18N4O5.C2HF3O2/c19-18(20)22-13-5-3-12(4-6-13)17(26)27-14-7-1-11(2-8-14)9-15(23)21-10-16(24)25;3-2(4,5)1(6)7/h1-8H,9-10H2,(H,21,23)(H,24,25)(H4,19,20,22);(H,6,7) CWYBOVRJKFYLKP-UHFFFAOYSA-N 50595340 CHEMBL5173692 Enteropeptidase Homo sapiens 540 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595340&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 164517148 482606192 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476650 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(N)=O)C(O)=O)cc1 InChI=1S/C20H21N5O6.C2HF3O2/c21-16(26)10-15(18(28)29)25-17(27)9-11-1-7-14(8-2-11)31-19(30)12-3-5-13(6-4-12)24-20(22)23;3-2(4,5)1(6)7/h1-8,15H,9-10H2,(H2,21,26)(H,25,27)(H,28,29)(H4,22,23,24);(H,6,7)/t15-;/m0./s1 MVSVAZZUVKTDED-RSAXXLAASA-N 50595341 CHEMBL5202535 Enteropeptidase Homo sapiens 310 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595341&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168293926 482606193 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476651 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CCC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7.C2HF3O2/c22-21(23)24-14-5-3-13(4-6-14)20(31)32-15-7-1-12(2-8-15)11-17(26)25-16(19(29)30)9-10-18(27)28;3-2(4,5)1(6)7/h1-8,16H,9-11H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24);(H,6,7)/t16-;/m0./s1 AWIHTKADQXTASI-NTISSMGPSA-N 50595342 CHEMBL5170208 Enteropeptidase Homo sapiens 120 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595342&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168270890 482606194 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476652 Cc1cc(ccc1NC(N)=N)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7/c1-11-8-13(4-7-15(11)25-21(22)23)20(31)32-14-5-2-12(3-6-14)9-17(26)24-16(19(29)30)10-18(27)28/h2-8,16H,9-10H2,1H3,(H,24,26)(H,27,28)(H,29,30)(H4,22,23,25)/t16-/m0/s1 FUIZWORATNERHR-INIZCTEOSA-N 50595343 CHEMBL5188778 Enteropeptidase Homo sapiens >3300 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595343&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168282350 482606195 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476653 Cc1cc(NC(N)=N)ccc1C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7/c1-11-8-13(24-21(22)23)4-7-15(11)20(31)32-14-5-2-12(3-6-14)9-17(26)25-16(19(29)30)10-18(27)28/h2-8,16H,9-10H2,1H3,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t16-/m0/s1 WAYKRJZJAWSVLC-INIZCTEOSA-N 50595344 CHEMBL5182789 Enteropeptidase Homo sapiens 940 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595344&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168280480 482606196 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476654 NC(=N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc2)c(Cl)c1 InChI=1S/C20H19ClN4O7/c21-14-8-11(24-20(22)23)3-6-13(14)19(31)32-12-4-1-10(2-5-12)7-16(26)25-15(18(29)30)9-17(27)28/h1-6,8,15H,7,9H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t15-/m0/s1 NGJQYQBMVLBYEG-HNNXBMFYSA-N 50595345 CHEMBL5182234 Enteropeptidase Homo sapiens 57 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595345&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168273915 482606197 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476655 NC(=N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc2)c(F)c1 InChI=1S/C20H19FN4O7/c21-14-8-11(24-20(22)23)3-6-13(14)19(31)32-12-4-1-10(2-5-12)7-16(26)25-15(18(29)30)9-17(27)28/h1-6,8,15H,7,9H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t15-/m0/s1 XHWITOQXWOOYIJ-HNNXBMFYSA-N 50595346 CHEMBL5189108 Enteropeptidase Homo sapiens 7.4 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595346&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168279450 482606198 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476656 NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc2CC(CC(=O)N[C@@H](CC(O)=O)C(O)=O)Oc2c1 InChI=1S/C22H22N4O8/c23-22(24)25-13-4-1-11(2-5-13)21(32)34-14-6-3-12-7-15(33-17(12)8-14)9-18(27)26-16(20(30)31)10-19(28)29/h1-6,8,15-16H,7,9-10H2,(H,26,27)(H,28,29)(H,30,31)(H4,23,24,25)/t15?,16-/m0/s1 RBADOYMMQHZSAY-LYKKTTPLSA-N 50595347 CHEMBL5169835 Enteropeptidase Homo sapiens 180 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595347&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168271027 482606199 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476657 NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc2[C@@H](CC(=O)N[C@@H](CC(O)=O)C(O)=O)COc2c1 InChI=1S/C22H22N4O8/c23-22(24)25-13-3-1-11(2-4-13)21(32)34-14-5-6-15-12(10-33-17(15)8-14)7-18(27)26-16(20(30)31)9-19(28)29/h1-6,8,12,16H,7,9-10H2,(H,26,27)(H,28,29)(H,30,31)(H4,23,24,25)/t12-,16-/m0/s1 PUZUTMLAAWVCCV-LRDDRELGSA-N 50595348 CHEMBL5170585 Enteropeptidase Homo sapiens 84 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595348&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 118290564 482606200 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476658 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H18N4O7.C2HF3O2/c20-19(21)22-12-6-4-10(5-7-12)18(29)30-13-3-1-2-11(8-13)16(26)23-14(17(27)28)9-15(24)25;3-2(4,5)1(6)7/h1-8,14H,9H2,(H,23,26)(H,24,25)(H,27,28)(H4,20,21,22);(H,6,7)/t14-;/m0./s1 WEYBFNKYMNSUKQ-UQKRIMTDSA-N 50595349 CHEMBL5202756 Enteropeptidase Homo sapiens 13 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595349&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168292880 482606201 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476659 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C20H20N4O7.C2HF3O2/c21-20(22)23-13-6-4-12(5-7-13)19(30)31-14-3-1-2-11(8-14)9-16(25)24-15(18(28)29)10-17(26)27;3-2(4,5)1(6)7/h1-8,15H,9-10H2,(H,24,25)(H,26,27)(H,28,29)(H4,21,22,23);(H,6,7)/t15-;/m0./s1 POFPPQWVXGPJAA-RSAXXLAASA-N 50595350 CHEMBL5182597 Enteropeptidase Homo sapiens 32 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595350&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168279076 482606202 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476660 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(cc1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H18N4O7.C2HF3O2/c20-19(21)22-12-5-1-11(2-6-12)18(29)30-13-7-3-10(4-8-13)16(26)23-14(17(27)28)9-15(24)25;3-2(4,5)1(6)7/h1-8,14H,9H2,(H,23,26)(H,24,25)(H,27,28)(H4,20,21,22);(H,6,7)/t14-;/m0./s1 LKBHXIGARNMCAY-UQKRIMTDSA-N 50595351 CHEMBL5200092 Enteropeptidase Homo sapiens 65 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595351&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168291219 482606203 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476661 NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C1=NO[C@@](CC(O)=O)(C1)C(O)=O InChI=1S/C20H18N4O7/c21-19(22)23-13-6-4-11(5-7-13)17(27)30-14-3-1-2-12(8-14)15-9-20(18(28)29,31-24-15)10-16(25)26/h1-8H,9-10H2,(H,25,26)(H,28,29)(H4,21,22,23)/t20-/m1/s1 KVQMAUMDMPEQBA-HXUWFJFHSA-N 50595352 CHEMBL5175180 Enteropeptidase Homo sapiens 20 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595352&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 91827417 482606204 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476662 NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C1=NO[C@](CC(O)=O)(C1)C(O)=O InChI=1S/C20H18N4O7/c21-19(22)23-13-6-4-11(5-7-13)17(27)30-14-3-1-2-12(8-14)15-9-20(18(28)29,31-24-15)10-16(25)26/h1-8H,9-10H2,(H,25,26)(H,28,29)(H4,21,22,23)/t20-/m0/s1 KVQMAUMDMPEQBA-FQEVSTJZSA-N 50595353 CHEMBL5179372 Enteropeptidase Homo sapiens 26 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595353&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 118292755 482606205 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476663 Cl.Cc1cc(OC(=O)c2ccc(NC(N)=N)cc2)no1 InChI=1S/C12H12N4O3.ClH/c1-7-6-10(16-19-7)18-11(17)8-2-4-9(5-3-8)15-12(13)14;/h2-6H,1H3,(H4,13,14,15);1H LMVIONPUKHVJBQ-UHFFFAOYSA-N 50595338 CHEMBL5190122 Enteropeptidase Homo sapiens 140 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595338&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168283960 482606190 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476664 CS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccccc1 InChI=1S/C14H13N3O2.CH4O3S/c15-14(16)17-11-8-6-10(7-9-11)13(18)19-12-4-2-1-3-5-12;1-5(2,3)4/h1-9H,(H4,15,16,17);1H3,(H,2,3,4) KSPAQJJGAABPRL-UHFFFAOYSA-N 50595339 CHEMBL5205880 Enteropeptidase Homo sapiens 400 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595339&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 159228495 482606191 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476665 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)NCC(O)=O)cc1 InChI=1S/C18H18N4O5.C2HF3O2/c19-18(20)22-13-5-3-12(4-6-13)17(26)27-14-7-1-11(2-8-14)9-15(23)21-10-16(24)25;3-2(4,5)1(6)7/h1-8H,9-10H2,(H,21,23)(H,24,25)(H4,19,20,22);(H,6,7) CWYBOVRJKFYLKP-UHFFFAOYSA-N 50595340 CHEMBL5173692 Enteropeptidase Homo sapiens 30 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595340&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 164517148 482606192 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476666 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(N)=O)C(O)=O)cc1 InChI=1S/C20H21N5O6.C2HF3O2/c21-16(26)10-15(18(28)29)25-17(27)9-11-1-7-14(8-2-11)31-19(30)12-3-5-13(6-4-12)24-20(22)23;3-2(4,5)1(6)7/h1-8,15H,9-10H2,(H2,21,26)(H,25,27)(H,28,29)(H4,22,23,24);(H,6,7)/t15-;/m0./s1 MVSVAZZUVKTDED-RSAXXLAASA-N 50595341 CHEMBL5202535 Enteropeptidase Homo sapiens 23 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595341&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168293926 482606193 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476667 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CCC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7.C2HF3O2/c22-21(23)24-14-5-3-13(4-6-14)20(31)32-15-7-1-12(2-8-15)11-17(26)25-16(19(29)30)9-10-18(27)28;3-2(4,5)1(6)7/h1-8,16H,9-11H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24);(H,6,7)/t16-;/m0./s1 AWIHTKADQXTASI-NTISSMGPSA-N 50595342 CHEMBL5170208 Enteropeptidase Homo sapiens 7.9 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595342&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168270890 482606194 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476668 Cc1cc(ccc1NC(N)=N)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7/c1-11-8-13(4-7-15(11)25-21(22)23)20(31)32-14-5-2-12(3-6-14)9-17(26)24-16(19(29)30)10-18(27)28/h2-8,16H,9-10H2,1H3,(H,24,26)(H,27,28)(H,29,30)(H4,22,23,25)/t16-/m0/s1 FUIZWORATNERHR-INIZCTEOSA-N 50595343 CHEMBL5188778 Enteropeptidase Homo sapiens 680 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595343&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168282350 482606195 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476669 Cc1cc(NC(N)=N)ccc1C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C21H22N4O7/c1-11-8-13(24-21(22)23)4-7-15(11)20(31)32-14-5-2-12(3-6-14)9-17(26)25-16(19(29)30)10-18(27)28/h2-8,16H,9-10H2,1H3,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t16-/m0/s1 WAYKRJZJAWSVLC-INIZCTEOSA-N 50595344 CHEMBL5182789 Enteropeptidase Homo sapiens 54 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595344&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168280480 482606196 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476670 NC(=N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc2)c(Cl)c1 InChI=1S/C20H19ClN4O7/c21-14-8-11(24-20(22)23)3-6-13(14)19(31)32-12-4-1-10(2-5-12)7-16(26)25-15(18(29)30)9-17(27)28/h1-6,8,15H,7,9H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t15-/m0/s1 NGJQYQBMVLBYEG-HNNXBMFYSA-N 50595345 CHEMBL5182234 Enteropeptidase Homo sapiens 5.6 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595345&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168273915 482606197 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476671 NC(=N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc2)c(F)c1 InChI=1S/C20H19FN4O7/c21-14-8-11(24-20(22)23)3-6-13(14)19(31)32-12-4-1-10(2-5-12)7-16(26)25-15(18(29)30)9-17(27)28/h1-6,8,15H,7,9H2,(H,25,26)(H,27,28)(H,29,30)(H4,22,23,24)/t15-/m0/s1 XHWITOQXWOOYIJ-HNNXBMFYSA-N 50595346 CHEMBL5189108 Enteropeptidase Homo sapiens 0.810000 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595346&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168279450 482606198 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476672 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H18N4O7.C2HF3O2/c20-19(21)22-12-6-4-10(5-7-12)18(29)30-13-3-1-2-11(8-13)16(26)23-14(17(27)28)9-15(24)25;3-2(4,5)1(6)7/h1-8,14H,9H2,(H,23,26)(H,24,25)(H,27,28)(H4,20,21,22);(H,6,7)/t14-;/m0./s1 WEYBFNKYMNSUKQ-UQKRIMTDSA-N 50595349 CHEMBL5202756 Enteropeptidase Homo sapiens 0.820000 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595349&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168292880 482606201 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476673 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C20H20N4O7.C2HF3O2/c21-20(22)23-13-6-4-12(5-7-13)19(30)31-14-3-1-2-11(8-14)9-16(25)24-15(18(28)29)10-17(26)27;3-2(4,5)1(6)7/h1-8,15H,9-10H2,(H,24,25)(H,26,27)(H,28,29)(H4,21,22,23);(H,6,7)/t15-;/m0./s1 POFPPQWVXGPJAA-RSAXXLAASA-N 50595350 CHEMBL5182597 Enteropeptidase Homo sapiens 1.6 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595350&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168279076 482606202 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476674 OC(=O)C(F)(F)F.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(cc1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C19H18N4O7.C2HF3O2/c20-19(21)22-12-5-1-11(2-6-12)18(29)30-13-7-3-10(4-8-13)16(26)23-14(17(27)28)9-15(24)25;3-2(4,5)1(6)7/h1-8,14H,9H2,(H,23,26)(H,24,25)(H,27,28)(H4,20,21,22);(H,6,7)/t14-;/m0./s1 LKBHXIGARNMCAY-UQKRIMTDSA-N 50595351 CHEMBL5200092 Enteropeptidase Homo sapiens 3.2 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595351&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168291219 482606203 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476675 NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc2CC(CC(=O)N[C@@H](CC(O)=O)C(O)=O)Oc2c1 InChI=1S/C22H22N4O8/c23-22(24)25-13-4-1-11(2-5-13)21(32)34-14-6-3-12-7-15(33-17(12)8-14)9-18(27)26-16(20(30)31)10-19(28)29/h1-6,8,15-16H,7,9-10H2,(H,26,27)(H,28,29)(H,30,31)(H4,23,24,25)/t15?,16-/m0/s1 RBADOYMMQHZSAY-LYKKTTPLSA-N 50595347 CHEMBL5169835 Enteropeptidase Homo sapiens 14 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595347&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168271027 482606199 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476676 NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc2[C@@H](CC(=O)N[C@@H](CC(O)=O)C(O)=O)COc2c1 InChI=1S/C22H22N4O8/c23-22(24)25-13-3-1-11(2-4-13)21(32)34-14-5-6-15-12(10-33-17(15)8-14)7-18(27)26-16(20(30)31)9-19(28)29/h1-6,8,12,16H,7,9-10H2,(H,26,27)(H,28,29)(H,30,31)(H4,23,24,25)/t12-,16-/m0/s1 PUZUTMLAAWVCCV-LRDDRELGSA-N 50595348 CHEMBL5170585 Enteropeptidase Homo sapiens 7.7 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595348&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 118290564 482606200 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476677 NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C1=NO[C@@](CC(O)=O)(C1)C(O)=O InChI=1S/C20H18N4O7/c21-19(22)23-13-6-4-11(5-7-13)17(27)30-14-3-1-2-12(8-14)15-9-20(18(28)29,31-24-15)10-16(25)26/h1-8H,9-10H2,(H,25,26)(H,28,29)(H4,21,22,23)/t20-/m1/s1 KVQMAUMDMPEQBA-HXUWFJFHSA-N 50595352 CHEMBL5175180 Enteropeptidase Homo sapiens 1.2 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595352&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 91827417 482606204 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476678 NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)C1=NO[C@](CC(O)=O)(C1)C(O)=O InChI=1S/C20H18N4O7/c21-19(22)23-13-6-4-11(5-7-13)17(27)30-14-3-1-2-12(8-14)15-9-20(18(28)29,31-24-15)10-16(25)26/h1-8H,9-10H2,(H,25,26)(H,28,29)(H4,21,22,23)/t20-/m0/s1 KVQMAUMDMPEQBA-FQEVSTJZSA-N 50595353 CHEMBL5179372 Enteropeptidase Homo sapiens 1.8 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595353&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 118292755 482606205 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51476679 Cl.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc1 InChI=1S/C20H20N4O7.ClH/c21-20(22)23-13-5-3-12(4-6-13)19(30)31-14-7-1-11(2-8-14)9-16(25)24-15(18(28)29)10-17(26)27;/h1-8,15H,9-10H2,(H,24,25)(H,26,27)(H,28,29)(H4,21,22,23);1H/t15-;/m0./s1 FLLBWNKVJUZVQT-RSAXXLAASA-N 50595337 CHEMBL5195621 Enteropeptidase Homo sapiens 5.9 ChEMBL 10.7270/Q208699D 35686954 Ikeda, Z; Kakegawa, K; Kikuchi, F; Itono, S; Oki, H; Yashiro, H; Hiyoshi, H; Tsuchimori, K; Hamagami, K; Watanabe, M; Sasaki, M; Ishihara, Y; Tohyama, K; Kitazaki, T; Maekawa, T; Sasaki, M Takeda Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50595337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50595337&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 168289255 482606189 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 7WQW,7WQX,7WQZ,7WR7,8H3S,8H3U Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563806 NC(=N)Nc1ccc2c(CCCCOc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C23H24N4O8/c24-23(25)26-13-7-8-14-12(10-13)4-1-2-9-34-19-15(5-3-6-17(19)35-22(14)33)20(30)27-16(21(31)32)11-18(28)29/h3,5-8,10,16H,1-2,4,9,11H2,(H,27,30)(H,28,29)(H,31,32)(H4,24,25,26)/t16-/m0/s1 JOEZCLJLASAPKY-INIZCTEOSA-N 50628764 CHEMBL5418103 Enteropeptidase Homo sapiens 26 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628764&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563807 NC(=N)Nc1ccc2c(CCCOc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O8/c23-22(24)25-12-6-7-13-11(9-12)3-2-8-33-18-14(4-1-5-16(18)34-21(13)32)19(29)26-15(20(30)31)10-17(27)28/h1,4-7,9,15H,2-3,8,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t15-/m0/s1 ANRCLDWFMUYQBV-HNNXBMFYSA-N 50628765 CHEMBL5415486 Enteropeptidase Homo sapiens 9.4 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628765&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563808 NC(=N)Nc1ccc2c(OCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O8/c23-22(24)25-11-6-7-14-17(9-11)33-8-2-4-12-13(3-1-5-16(12)34-21(14)32)19(29)26-15(20(30)31)10-18(27)28/h1,3,5-7,9,15H,2,4,8,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t15-/m0/s1 RDMKXQXZCWREDZ-HNNXBMFYSA-N 50628766 CHEMBL5433360 Enteropeptidase Homo sapiens 8.7 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628766&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563809 NC(=N)Nc1ccc2c(CCCCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C25H28N4O7/c26-25(27)28-15-10-11-16-14(12-15)6-3-1-2-4-7-17-18(8-5-9-20(17)36-24(16)35)22(32)29-19(23(33)34)13-21(30)31/h5,8-12,19H,1-4,6-7,13H2,(H,29,32)(H,30,31)(H,33,34)(H4,26,27,28)/t19-/m0/s1 CZDSYPDNMSDBKU-IBGZPJMESA-N 50628767 CHEMBL5418493 Enteropeptidase Homo sapiens 2500 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628767&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563810 NC(=N)Nc1ccc2c(CCCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C24H26N4O7/c25-24(26)27-14-9-10-15-13(11-14)5-2-1-3-6-16-17(7-4-8-19(16)35-23(15)34)21(31)28-18(22(32)33)12-20(29)30/h4,7-11,18H,1-3,5-6,12H2,(H,28,31)(H,29,30)(H,32,33)(H4,25,26,27)/t18-/m0/s1 COOGFPDLHFDISS-SFHVURJKSA-N 50628768 CHEMBL5398070 Enteropeptidase Homo sapiens 96 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628768&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563811 NC(=N)Nc1ccc2c(CCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C23H24N4O7/c24-23(25)26-13-8-9-14-12(10-13)4-1-2-5-15-16(6-3-7-18(15)34-22(14)33)20(30)27-17(21(31)32)11-19(28)29/h3,6-10,17H,1-2,4-5,11H2,(H,27,30)(H,28,29)(H,31,32)(H4,24,25,26)/t17-/m0/s1 PKMIOKPYZYJYFX-KRWDZBQOSA-N 50628769 CHEMBL5428323 Enteropeptidase Homo sapiens 93 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628769&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563812 NC(=N)Nc1ccc2c(CCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O7/c23-22(24)25-12-7-8-13-11(9-12)3-1-4-14-15(5-2-6-17(14)33-21(13)32)19(29)26-16(20(30)31)10-18(27)28/h2,5-9,16H,1,3-4,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t16-/m0/s1 AVZVOAYNKPZQQY-INIZCTEOSA-N 50628770 CHEMBL5413614 Enteropeptidase Homo sapiens 430 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628770&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563813 OC(=O)C(F)(F)F.Cc1c(OC(=O)c2ccc(NC(N)=N)cc2)cccc1C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20N4O7.C2HF3O2/c1-10-13(17(27)24-14(18(28)29)9-16(25)26)3-2-4-15(10)31-19(30)11-5-7-12(8-6-11)23-20(21)22;3-2(4,5)1(6)7/h2-8,14H,9H2,1H3,(H,24,27)(H,25,26)(H,28,29)(H4,21,22,23);(H,6,7)/t14-;/m0./s1 VMJKXRJUFVPFFE-UQKRIMTDSA-N 50628771 CHEMBL5407739 Enteropeptidase Homo sapiens 69 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628771&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563814 OC(=O)C(F)(F)F.Cc1ccc(cc1OC(=O)c1ccc(NC(N)=N)cc1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20N4O7.C2HF3O2/c1-10-2-3-12(17(27)24-14(18(28)29)9-16(25)26)8-15(10)31-19(30)11-4-6-13(7-5-11)23-20(21)22;3-2(4,5)1(6)7/h2-8,14H,9H2,1H3,(H,24,27)(H,25,26)(H,28,29)(H4,21,22,23);(H,6,7)/t14-;/m0./s1 OFGJELJQSNKRTE-UQKRIMTDSA-N 50628772 CHEMBL5401618 Enteropeptidase Homo sapiens >3300 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628772&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563815 NC(=N)Nc1ccc2c(CCCCOc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C23H24N4O8/c24-23(25)26-13-7-8-14-12(10-13)4-1-2-9-34-19-15(5-3-6-17(19)35-22(14)33)20(30)27-16(21(31)32)11-18(28)29/h3,5-8,10,16H,1-2,4,9,11H2,(H,27,30)(H,28,29)(H,31,32)(H4,24,25,26)/t16-/m0/s1 JOEZCLJLASAPKY-INIZCTEOSA-N 50628764 CHEMBL5418103 Enteropeptidase Homo sapiens 1.7 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628764&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563816 NC(=N)Nc1ccc2c(CCCOc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O8/c23-22(24)25-12-6-7-13-11(9-12)3-2-8-33-18-14(4-1-5-16(18)34-21(13)32)19(29)26-15(20(30)31)10-17(27)28/h1,4-7,9,15H,2-3,8,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t15-/m0/s1 ANRCLDWFMUYQBV-HNNXBMFYSA-N 50628765 CHEMBL5415486 Enteropeptidase Homo sapiens 0.410000 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628765&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563817 NC(=N)Nc1ccc2c(OCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O8/c23-22(24)25-11-6-7-14-17(9-11)33-8-2-4-12-13(3-1-5-16(12)34-21(14)32)19(29)26-15(20(30)31)10-18(27)28/h1,3,5-7,9,15H,2,4,8,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t15-/m0/s1 RDMKXQXZCWREDZ-HNNXBMFYSA-N 50628766 CHEMBL5433360 Enteropeptidase Homo sapiens 0.690000 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628766&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563818 NC(=N)Nc1ccc2c(CCCCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C25H28N4O7/c26-25(27)28-15-10-11-16-14(12-15)6-3-1-2-4-7-17-18(8-5-9-20(17)36-24(16)35)22(32)29-19(23(33)34)13-21(30)31/h5,8-12,19H,1-4,6-7,13H2,(H,29,32)(H,30,31)(H,33,34)(H4,26,27,28)/t19-/m0/s1 CZDSYPDNMSDBKU-IBGZPJMESA-N 50628767 CHEMBL5418493 Enteropeptidase Homo sapiens 81 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628767&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563819 NC(=N)Nc1ccc2c(CCCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C24H26N4O7/c25-24(26)27-14-9-10-15-13(11-14)5-2-1-3-6-16-17(7-4-8-19(16)35-23(15)34)21(31)28-18(22(32)33)12-20(29)30/h4,7-11,18H,1-3,5-6,12H2,(H,28,31)(H,29,30)(H,32,33)(H4,25,26,27)/t18-/m0/s1 COOGFPDLHFDISS-SFHVURJKSA-N 50628768 CHEMBL5398070 Enteropeptidase Homo sapiens 2.9 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628768&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563820 NC(=N)Nc1ccc2c(CCCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C23H24N4O7/c24-23(25)26-13-8-9-14-12(10-13)4-1-2-5-15-16(6-3-7-18(15)34-22(14)33)20(30)27-17(21(31)32)11-19(28)29/h3,6-10,17H,1-2,4-5,11H2,(H,27,30)(H,28,29)(H,31,32)(H4,24,25,26)/t17-/m0/s1 PKMIOKPYZYJYFX-KRWDZBQOSA-N 50628769 CHEMBL5428323 Enteropeptidase Homo sapiens 3.2 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628769&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563821 NC(=N)Nc1ccc2c(CCCc3c(OC2=O)cccc3C(=O)N[C@@H](CC(O)=O)C(O)=O)c1 InChI=1S/C22H22N4O7/c23-22(24)25-12-7-8-13-11(9-12)3-1-4-14-15(5-2-6-17(14)33-21(13)32)19(29)26-16(20(30)31)10-18(27)28/h2,5-9,16H,1,3-4,10H2,(H,26,29)(H,27,28)(H,30,31)(H4,23,24,25)/t16-/m0/s1 AVZVOAYNKPZQQY-INIZCTEOSA-N 50628770 CHEMBL5413614 Enteropeptidase Homo sapiens 22 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628770&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563822 OC(=O)C(F)(F)F.Cc1c(OC(=O)c2ccc(NC(N)=N)cc2)cccc1C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20N4O7.C2HF3O2/c1-10-13(17(27)24-14(18(28)29)9-16(25)26)3-2-4-15(10)31-19(30)11-5-7-12(8-6-11)23-20(21)22;3-2(4,5)1(6)7/h2-8,14H,9H2,1H3,(H,24,27)(H,25,26)(H,28,29)(H4,21,22,23);(H,6,7)/t14-;/m0./s1 VMJKXRJUFVPFFE-UQKRIMTDSA-N 50628771 CHEMBL5407739 Enteropeptidase Homo sapiens 4.4 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628771&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7 51563823 OC(=O)C(F)(F)F.Cc1ccc(cc1OC(=O)c1ccc(NC(N)=N)cc1)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C20H20N4O7.C2HF3O2/c1-10-2-3-12(17(27)24-14(18(28)29)9-16(25)26)8-15(10)31-19(30)11-4-6-13(7-5-11)23-20(21)22;3-2(4,5)1(6)7/h2-8,14H,9H2,1H3,(H,24,27)(H,25,26)(H,28,29)(H4,21,22,23);(H,6,7)/t14-;/m0./s1 OFGJELJQSNKRTE-UQKRIMTDSA-N 50628772 CHEMBL5401618 Enteropeptidase Homo sapiens 710 ChEMBL 10.1016/j.bmc.2023.117462 10.7270/Q2GM8CQ5 37683572 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5894&target=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628772&enzyme=Enteropeptidase&column=ki&startPg=0&Increment=50&submit=Search 1 MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH 8H3U,8H3S,7WQX,7WR7,7WQZ,7WQW Enteropeptidase ENTK_HUMAN P98073 Q2NKL7