BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 198703 COC(=O)c1cccc(CS(=O)(=O)N[C@H](CCCc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)c1 InChI=1S/C37H48N6O6S/c1-49-37(46)31-11-5-10-29(23-31)25-50(47,48)43-33(12-6-9-26-7-3-2-4-8-26)36(45)42-32(18-15-27-19-21-40-22-20-27)35(44)41-24-28-13-16-30(17-14-28)34(38)39/h2-5,7-8,10-11,13-14,16-17,23,27,32-33,40,43H,6,9,12,15,18-22,24-25H2,1H3,(H3,38,39)(H,41,44)(H,42,45)/t32-,33+/m0/s1 JPGNXUNXIAMWMQ-JHOUSYSJSA-N 108116 US8598206, Table 6, 3 Transcription initiation factor IIA subunit 1 Homo sapiens 920 US Patent 10.7270/Q25T3J5F aid1800212 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108116&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345754 186524986 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228195 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1 RUUQARAMINJWGP-RRPNLBNLSA-N 108118 US8598206, Table 6, 1 Transcription initiation factor IIA subunit 1 Homo sapiens 4700 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108118&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345654 186524988 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228196 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCc2ccncc2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C34H45N7O4S/c35-32(36)29-12-9-27(10-13-29)23-39-33(42)30(14-11-26-17-21-38-22-18-26)40-34(43)31(8-4-7-25-15-19-37-20-16-25)41-46(44,45)24-28-5-2-1-3-6-28/h1-3,5-6,9-10,12-13,15-16,19-20,26,30-31,38,41H,4,7-8,11,14,17-18,21-24H2,(H3,35,36)(H,39,42)(H,40,43)/t30-,31+/m0/s1 VNKFZBCCJJVXJG-IOWSJCHKSA-N 108117 US8598206, Table 6, 2 Transcription initiation factor IIA subunit 1 Homo sapiens 1200 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108117&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345653 186524987 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228198 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCc2ccccc2)NS(=O)(=O)Cc2cccc(c2)C(O)=O)cc1 InChI=1S/C36H46N6O6S/c37-33(38)29-15-12-27(13-16-29)23-40-34(43)31(17-14-26-18-20-39-21-19-26)41-35(44)32(11-5-8-25-6-2-1-3-7-25)42-49(47,48)24-28-9-4-10-30(22-28)36(45)46/h1-4,6-7,9-10,12-13,15-16,22,26,31-32,39,42H,5,8,11,14,17-21,23-24H2,(H3,37,38)(H,40,43)(H,41,44)(H,45,46)/t31-,32+/m0/s1 OITRKHUOZGPBJI-AJQTZOPKSA-N 108095 US8598206, Table 6, 4 Transcription initiation factor IIA subunit 1 Homo sapiens 4400 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108095&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345755 186524965 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228199 CC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C35H51N7O5S/c1-25(43)42-21-17-27(18-22-42)10-14-32(41-48(46,47)24-29-5-3-2-4-6-29)35(45)40-31(13-9-26-15-19-38-20-16-26)34(44)39-23-28-7-11-30(12-8-28)33(36)37/h2-8,11-12,26-27,31-32,38,41H,9-10,13-24H2,1H3,(H3,36,37)(H,39,44)(H,40,45)/t31-,32+/m0/s1 XATHBXYKVIAZOR-AJQTZOPKSA-N 108096 US8598206, Table 6, 5 Transcription initiation factor IIA subunit 1 Homo sapiens 8000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108096&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345860 186524966 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228200 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCC2CCNCC2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C34H51N7O4S/c35-32(36)29-12-9-27(10-13-29)23-39-33(42)30(14-11-26-17-21-38-22-18-26)40-34(43)31(8-4-7-25-15-19-37-20-16-25)41-46(44,45)24-28-5-2-1-3-6-28/h1-3,5-6,9-10,12-13,25-26,30-31,37-38,41H,4,7-8,11,14-24H2,(H3,35,36)(H,39,42)(H,40,43)/t30-,31+/m0/s1 FDLUVBKZNIPEQR-IOWSJCHKSA-N 108097 US8598206, Table 6, 6 Transcription initiation factor IIA subunit 1 Homo sapiens 800 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108097&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53346079 186524967 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228201 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCC2CCN(CC2)C(=O)C2CC2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C37H53N7O5S/c38-34(39)30-10-6-28(7-11-30)24-41-35(45)32(14-8-26-16-20-40-21-17-26)42-36(46)33(43-50(48,49)25-29-4-2-1-3-5-29)15-9-27-18-22-44(23-19-27)37(47)31-12-13-31/h1-7,10-11,26-27,31-33,40,43H,8-9,12-25H2,(H3,38,39)(H,41,45)(H,42,46)/t32-,33+/m0/s1 DIFGLRSYVDIDJS-JHOUSYSJSA-N 108098 US8598206, Table 6, 7 Transcription initiation factor IIA subunit 1 Homo sapiens 8500 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108098&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345968 186524968 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228203 CC(=O)N1CCC(CCC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C36H53N7O5S/c1-26(44)43-22-18-27(19-23-43)8-5-9-33(42-49(47,48)25-30-6-3-2-4-7-30)36(46)41-32(15-12-28-16-20-39-21-17-28)35(45)40-24-29-10-13-31(14-11-29)34(37)38/h2-4,6-7,10-11,13-14,27-28,32-33,39,42H,5,8-9,12,15-25H2,1H3,(H3,37,38)(H,40,45)(H,41,46)/t32-,33+/m0/s1 QCJKXYYLKAMQSD-JHOUSYSJSA-N 47177 BDBM108100::US8598206, Table 6, 9 Transcription initiation factor IIA subunit 1 Homo sapiens 3800 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47177&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53346080 313362578 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228204 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCC2CCNCC2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C33H49N7O4S/c34-31(35)28-10-6-26(7-11-28)22-38-32(41)29(12-8-24-14-18-36-19-15-24)39-33(42)30(13-9-25-16-20-37-21-17-25)40-45(43,44)23-27-4-2-1-3-5-27/h1-7,10-11,24-25,29-30,36-37,40H,8-9,12-23H2,(H3,34,35)(H,38,41)(H,39,42)/t29-,30+/m0/s1 ZTJVQQCXGUIYTL-XZWHSSHBSA-N 108101 US8598206, Table 6, 10 Transcription initiation factor IIA subunit 1 Homo sapiens 4200 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108101&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53346181 186524971 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228205 COCC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C36H53N7O6S/c1-49-24-33(44)43-21-17-27(18-22-43)10-14-32(42-50(47,48)25-29-5-3-2-4-6-29)36(46)41-31(13-9-26-15-19-39-20-16-26)35(45)40-23-28-7-11-30(12-8-28)34(37)38/h2-8,11-12,26-27,31-32,39,42H,9-10,13-25H2,1H3,(H3,37,38)(H,40,45)(H,41,46)/t31-,32+/m0/s1 DTIUMOLBWQXRPH-AJQTZOPKSA-N 108102 US8598206, Table 6, 11 Transcription initiation factor IIA subunit 1 Homo sapiens 4500 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108102&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345862 186524972 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228206 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCc2ccncc2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C33H43N7O4S/c34-31(35)28-10-6-26(7-11-28)22-38-32(41)29(12-8-24-14-18-36-19-15-24)39-33(42)30(13-9-25-16-20-37-21-17-25)40-45(43,44)23-27-4-2-1-3-5-27/h1-7,10-11,16-17,20-21,24,29-30,36,40H,8-9,12-15,18-19,22-23H2,(H3,34,35)(H,38,41)(H,39,42)/t29-,30+/m0/s1 ZYKYKDNQGMXJQR-XZWHSSHBSA-N 47178 BDBM108103::US8598206, Table 6, 12 Transcription initiation factor IIA subunit 1 Homo sapiens 3900 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47178&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345752 313362579 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228207 CN(C)C(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C36H54N8O5S/c1-43(2)36(47)44-22-18-27(19-23-44)11-15-32(42-50(48,49)25-29-6-4-3-5-7-29)35(46)41-31(14-10-26-16-20-39-21-17-26)34(45)40-24-28-8-12-30(13-9-28)33(37)38/h3-9,12-13,26-27,31-32,39,42H,10-11,14-25H2,1-2H3,(H3,37,38)(H,40,45)(H,41,46)/t31-,32+/m0/s1 WYOJURVOHOBMRY-AJQTZOPKSA-N 108104 US8598206, Table 6, 13 Transcription initiation factor IIA subunit 1 Homo sapiens 13000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108104&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345967 186524974 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228208 CNC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C35H52N8O5S/c1-38-35(46)43-21-17-26(18-22-43)10-14-31(42-49(47,48)24-28-5-3-2-4-6-28)34(45)41-30(13-9-25-15-19-39-20-16-25)33(44)40-23-27-7-11-29(12-8-27)32(36)37/h2-8,11-12,25-26,30-31,39,42H,9-10,13-24H2,1H3,(H3,36,37)(H,38,46)(H,40,44)(H,41,45)/t30-,31+/m0/s1 OGCGKERBEQPTBU-IOWSJCHKSA-N 108105 US8598206, Table 6, 14 Transcription initiation factor IIA subunit 1 Homo sapiens 4800 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108105&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345863 186524975 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228209 CCCC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C37H55N7O5S/c1-2-6-34(45)44-23-19-28(20-24-44)12-16-33(43-50(48,49)26-30-7-4-3-5-8-30)37(47)42-32(15-11-27-17-21-40-22-18-27)36(46)41-25-29-9-13-31(14-10-29)35(38)39/h3-5,7-10,13-14,27-28,32-33,40,43H,2,6,11-12,15-26H2,1H3,(H3,38,39)(H,41,46)(H,42,47)/t32-,33+/m0/s1 GWZGMZVWURNLOZ-JHOUSYSJSA-N 108106 US8598206, Table 6, 15 Transcription initiation factor IIA subunit 1 Homo sapiens 5500 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108106&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345969 186524976 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228210 COC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C35H51N7O6S/c1-48-35(45)42-21-17-26(18-22-42)10-14-31(41-49(46,47)24-28-5-3-2-4-6-28)34(44)40-30(13-9-25-15-19-38-20-16-25)33(43)39-23-27-7-11-29(12-8-27)32(36)37/h2-8,11-12,25-26,30-31,38,41H,9-10,13-24H2,1H3,(H3,36,37)(H,39,43)(H,40,44)/t30-,31+/m0/s1 ZTXALZIIFRKUGE-IOWSJCHKSA-N 108107 US8598206, Table 6, 16 Transcription initiation factor IIA subunit 1 Homo sapiens 13000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108107&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345861 186524977 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228211 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCC2=CC=[N](O)C=C2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C34H46N7O5S/c35-32(36)29-12-9-27(10-13-29)23-38-33(42)30(14-11-26-15-19-37-20-16-26)39-34(43)31(8-4-7-25-17-21-41(44)22-18-25)40-47(45,46)24-28-5-2-1-3-6-28/h1-3,5-6,9-10,12-13,17-18,21-22,26,30-31,37,40,44H,4,7-8,11,14-16,19-20,23-24H2,(H3,35,36)(H,38,42)(H,39,43)/t30-,31+/m0/s1 LBBUQPWJBKYVNI-IOWSJCHKSA-N 108108 US8598206, 117::US8598206, 123 Transcription initiation factor IIA subunit 1 Homo sapiens 4900 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108108&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 91663788 186524978 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228212 CC(C)C(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C37H55N7O5S/c1-26(2)37(47)44-22-18-28(19-23-44)11-15-33(43-50(48,49)25-30-6-4-3-5-7-30)36(46)42-32(14-10-27-16-20-40-21-17-27)35(45)41-24-29-8-12-31(13-9-29)34(38)39/h3-9,12-13,26-28,32-33,40,43H,10-11,14-25H2,1-2H3,(H3,38,39)(H,41,45)(H,42,46)/t32-,33+/m0/s1 RRYHCECMCWJEIU-JHOUSYSJSA-N 108109 US8598206, 118::US8598206, 122 Transcription initiation factor IIA subunit 1 Homo sapiens 13000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108109&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345970 186524979 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228213 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCc2ccccc2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C35H46N6O4S/c36-33(37)30-17-14-28(15-18-30)24-39-34(42)31(19-16-27-20-22-38-23-21-27)40-35(43)32(13-7-12-26-8-3-1-4-9-26)41-46(44,45)25-29-10-5-2-6-11-29/h1-6,8-11,14-15,17-18,27,31-32,38,41H,7,12-13,16,19-25H2,(H3,36,37)(H,39,42)(H,40,43)/t31-,32+/m0/s1 MCDKKKIUEGNSPK-AJQTZOPKSA-N 108110 US8598206, Table 6, 19 Transcription initiation factor IIA subunit 1 Homo sapiens 240 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108110&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345652 186524980 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228214 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@H](NS(=O)(=O)Cc2ccccc2)c2ccccc2)cc1 InChI=1S/C32H40N6O4S/c33-30(34)27-14-11-24(12-15-27)21-36-31(39)28(16-13-23-17-19-35-20-18-23)37-32(40)29(26-9-5-2-6-10-26)38-43(41,42)22-25-7-3-1-4-8-25/h1-12,14-15,23,28-29,35,38H,13,16-22H2,(H3,33,34)(H,36,39)(H,37,40)/t28-,29+/m0/s1 BQJXMSPBOZFQJJ-URLMMPGGSA-N 108111 US8598206, Table 6, 20 Transcription initiation factor IIA subunit 1 Homo sapiens 1700 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108111&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345655 186524981 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228215 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCC2=CC=[N](O)C=C2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C33H44N7O5S/c34-31(35)28-10-6-26(7-11-28)22-37-32(41)29(12-8-24-14-18-36-19-15-24)38-33(42)30(13-9-25-16-20-40(43)21-17-25)39-46(44,45)23-27-4-2-1-3-5-27/h1-7,10-11,16-17,20-21,24,29-30,36,39,43H,8-9,12-15,18-19,22-23H2,(H3,34,35)(H,37,41)(H,38,42)/t29-,30+/m0/s1 CKZGCUFXVIRNEZ-XZWHSSHBSA-N 108112 US8598206, Table 6, 21 Transcription initiation factor IIA subunit 1 Homo sapiens 9000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108112&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 91663789 186524982 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228216 CC(C)C(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C37H55N7O5S/c1-26(2)37(47)44-22-18-28(19-23-44)11-15-33(43-50(48,49)25-30-6-4-3-5-7-30)36(46)42-32(14-10-27-16-20-40-21-17-27)35(45)41-24-29-8-12-31(13-9-29)34(38)39/h3-9,12-13,26-28,32-33,40,43H,10-11,14-25H2,1-2H3,(H3,38,39)(H,41,45)(H,42,46)/t32-,33+/m0/s1 RRYHCECMCWJEIU-JHOUSYSJSA-N 108109 US8598206, 118::US8598206, 122 Transcription initiation factor IIA subunit 1 Homo sapiens 13000 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108109&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53345970 186524979 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228217 NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCC2=CC=[N](O)C=C2)NS(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C34H46N7O5S/c35-32(36)29-12-9-27(10-13-29)23-38-33(42)30(14-11-26-15-19-37-20-16-26)39-34(43)31(8-4-7-25-17-21-41(44)22-18-25)40-47(45,46)24-28-5-2-1-3-6-28/h1-3,5-6,9-10,12-13,17-18,21-22,26,30-31,37,40,44H,4,7-8,11,14-16,19-20,23-24H2,(H3,35,36)(H,38,42)(H,39,43)/t30-,31+/m0/s1 LBBUQPWJBKYVNI-IOWSJCHKSA-N 108108 US8598206, 117::US8598206, 123 Transcription initiation factor IIA subunit 1 Homo sapiens 4900 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108108&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 91663788 186524978 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228218 COC(=O)N1CCC(CCC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C36H53N7O6S/c1-49-36(46)43-22-18-26(19-23-43)8-5-9-32(42-50(47,48)25-29-6-3-2-4-7-29)35(45)41-31(15-12-27-16-20-39-21-17-27)34(44)40-24-28-10-13-30(14-11-28)33(37)38/h2-4,6-7,10-11,13-14,26-27,31-32,39,42H,5,8-9,12,15-25H2,1H3,(H3,37,38)(H,40,44)(H,41,45)/t31-,32+/m0/s1 BJSIWIFJSRFHPS-AJQTZOPKSA-N 108115 US8598206, Table 6, 24 Transcription initiation factor IIA subunit 1 Homo sapiens 3600 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108115&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53346081 186524985 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9 228202 CCC(=O)N1CCC(CC[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCC2CCNCC2)C(=O)NCc2ccc(cc2)C(N)=N)CC1 InChI=1S/C36H53N7O5S/c1-2-33(44)43-22-18-27(19-23-43)11-15-32(42-49(47,48)25-29-6-4-3-5-7-29)36(46)41-31(14-10-26-16-20-39-21-17-26)35(45)40-24-28-8-12-30(13-9-28)34(37)38/h3-9,12-13,26-27,31-32,39,42H,2,10-11,14-25H2,1H3,(H3,37,38)(H,40,45)(H,41,46)/t31-,32+/m0/s1 LWFLIRIWEPBXFX-AJQTZOPKSA-N 108099 US8598206, Table 6, 8 Transcription initiation factor IIA subunit 1 Homo sapiens 5600 US Patent 10.7270/Q25T3J5F aid1800208 US8598206 Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A The Medicines Company (Leipzig) GmbH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=108099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5851&target=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=108099&enzyme=Transcription+initiation+factor+IIA+subunit+1&column=ki&startPg=0&Increment=50&submit=Search 53346082 186524969 1 MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 1NVP,5FUR,5IY6,5IY7,5IY8,5IY9,5IYA,5IYB,5IYC,5IYD,5M4S,6O9L,7EDX,7EG7,7EG8,7EG9,7EGA,7EGB,7EGC,7EGD,7EGI,7EGJ,7LBM,7NVR,7NVS,7NVT,7NVU,7NVY,7NVZ,7NW0,7ZWC,7ZWD,7ZX7,7ZX8,7ZXE,8BVW,8BYQ,8BZ1 Transcription initiation factor IIA subunit 1 TF2AA_HUMAN P52655 Q3KNQ9