BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
623003	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C20H20N6O4/c1-25-12-15-18(24-25)20(29)21-8-3-9-30-16-6-7-17(27)26(23-16)11-13-4-2-5-14(10-13)19(28)22-15/h2,4-7,10,12H,3,8-9,11H2,1H3,(H,21,29)(H,22,28)	GKSLYGBWVIREPH-UHFFFAOYSA-N	318823	US10517872, Compound 1::US9624246, Compound 1	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318823&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447249	384222112							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623005	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cnn(CCNC(=O)c2n1)c4)c3	InChI=1S/C22H20N8O3/c1-28-13-18-20(27-28)22(33)23-7-8-29-12-16(10-24-29)17-5-6-19(31)30(26-17)11-14-3-2-4-15(9-14)21(32)25-18/h2-6,9-10,12-13H,7-8,11H2,1H3,(H,23,33)(H,25,32)	WGAIHKWWBXYAKM-UHFFFAOYSA-N	318825	US10517872, Compound 2::US9624246, Compound 2	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318825&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470005	384222114							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623007	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cncc(CNC(=O)c2n1)c4)c3	InChI=1S/C23H19N7O3/c1-29-13-19-21(28-29)23(33)25-10-15-8-17(11-24-9-15)18-5-6-20(31)30(27-18)12-14-3-2-4-16(7-14)22(32)26-19/h2-9,11,13H,10,12H2,1H3,(H,25,33)(H,26,32)	OWGPCYDHMUISML-UHFFFAOYSA-N	318826	US10517872, Compound 3::US9624246, Compound 3	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318826&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470030	384222115							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623009	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C19H18N6O4/c1-24-11-14-17(23-24)19(28)20-7-8-29-15-5-6-16(26)25(22-15)10-12-3-2-4-13(9-12)18(27)21-14/h2-6,9,11H,7-8,10H2,1H3,(H,20,28)(H,21,27)	ATLIZTAFGKXPLE-UHFFFAOYSA-N	318827	US10517872, Compound 4::US9624246, Compound 4	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318827&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470006	384222116							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623011	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C21H22N6O4/c1-26-13-16-19(25-26)21(30)22-9-2-3-10-31-17-7-8-18(28)27(24-17)12-14-5-4-6-15(11-14)20(29)23-16/h4-8,11,13H,2-3,9-10,12H2,1H3,(H,22,30)(H,23,29)	XHWNTEWYWFMZBL-UHFFFAOYSA-N	318828	US10517872, Compound 5::US9624246, Compound 5	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318828&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447240	384222117							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623013	O=C1NCCCOc2ccc(=O)n(Cc3cccc(c3)C(=O)Nc3cn(nc13)C1CCOCC1)n2	InChI=1S/C24H26N6O5/c31-21-6-5-20-27-30(21)14-16-3-1-4-17(13-16)23(32)26-19-15-29(18-7-11-34-12-8-18)28-22(19)24(33)25-9-2-10-35-20/h1,3-6,13,15,18H,2,7-12,14H2,(H,25,33)(H,26,32)	WJPDPEBXKRAWLO-UHFFFAOYSA-N	318829	US10517872, Compound 6::US9624246, Compound 6	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318829&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470008	384222118							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623015	CC(C)(C)n1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C23H26N6O4/c1-23(2,3)29-14-17-20(27-29)22(32)24-10-5-11-33-18-8-9-19(30)28(26-18)13-15-6-4-7-16(12-15)21(31)25-17/h4,6-9,12,14H,5,10-11,13H2,1-3H3,(H,24,32)(H,25,31)	XMDZLJRPNPTNNM-UHFFFAOYSA-N	318830	US10517872, Compound 7::US9624246, Compound 7	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318830&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470039	384222119							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623017	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)n3	InChI=1S/C19H19N7O4/c1-25-11-14-17(24-25)19(29)20-8-3-9-30-15-6-7-16(27)26(23-15)10-12-4-2-5-13(21-12)18(28)22-14/h2,4-7,11H,3,8-10H2,1H3,(H,20,29)(H,22,28)	JTDOHCWXAJEHMM-UHFFFAOYSA-N	318831	US10517872, Compound 8::US9624246, Compound 8	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318831&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447275	384222120							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623019	O=C1NCCCOc2ccc(=O)n(Cc3cccc(n3)C(=O)Nc3cn(nc13)C1CCOCC1)n2	InChI=1S/C23H25N7O5/c31-20-6-5-19-27-30(20)13-15-3-1-4-17(25-15)22(32)26-18-14-29(16-7-11-34-12-8-16)28-21(18)23(33)24-9-2-10-35-19/h1,3-6,14,16H,2,7-13H2,(H,24,33)(H,26,32)	VWMDHJMEUZNQNF-UHFFFAOYSA-N	318832	US10517872, Compound 9::US9624246, Compound 9	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318832&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122471471	384222121							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623021	CC(C)(C)n1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)n3	InChI=1S/C22H25N7O4/c1-22(2,3)29-13-16-19(27-29)21(32)23-10-5-11-33-17-8-9-18(30)28(26-17)12-14-6-4-7-15(24-14)20(31)25-16/h4,6-9,13H,5,10-12H2,1-3H3,(H,23,32)(H,25,31)	AHFFIIHDSQMDME-UHFFFAOYSA-N	318833	US10517872, Compound 10::US9624246, Compound 10	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318833&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470054	384222122							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623023	OC1CNC(=O)c2nn(cc2NC(=O)c2cccc(Cn3nc(OC1)ccc3=O)c2)C1CCOCC1	InChI=1S/C24H26N6O6/c31-18-11-25-24(34)22-19(13-29(28-22)17-6-8-35-9-7-17)26-23(33)16-3-1-2-15(10-16)12-30-21(32)5-4-20(27-30)36-14-18/h1-5,10,13,17-18,31H,6-9,11-12,14H2,(H,25,34)(H,26,33)	KNCBISXOBZEGTD-UHFFFAOYSA-N	318834	US9624246, Compound 11	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318834&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470007	384222123							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623025	Cn1cc2NC(=O)c3cccc(Cn4nc(OCC(O)CNC(=O)c2n1)ccc4=O)c3	InChI=1S/C20H20N6O5/c1-25-10-15-18(24-25)20(30)21-8-14(27)11-31-16-5-6-17(28)26(23-16)9-12-3-2-4-13(7-12)19(29)22-15/h2-7,10,14,27H,8-9,11H2,1H3,(H,21,30)(H,22,29)	FNRWLDQIJWSZPQ-UHFFFAOYSA-N	318835	US10517872, Compound 12::US9624246, Compound 12	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318835&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470009	384222124							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623027	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4ccnc(CNC(=O)c2n1)c4)c3	InChI=1S/C23H19N7O3/c1-29-13-19-21(28-29)23(33)25-11-17-10-15(7-8-24-17)18-5-6-20(31)30(27-18)12-14-3-2-4-16(9-14)22(32)26-19/h2-10,13H,11-12H2,1H3,(H,25,33)(H,26,32)	ZGPAYCQEDZYSFA-UHFFFAOYSA-N	318836	US10517872, Compound 13::US9624246, Compound 13	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318836&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470010	384222125							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623029	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc(CCNC(=O)c2n1)c4)c3	InChI=1S/C25H22N6O3/c1-30-15-21-23(29-30)25(34)26-11-10-16-4-2-6-18(12-16)20-8-9-22(32)31(28-20)14-17-5-3-7-19(13-17)24(33)27-21/h2-9,12-13,15H,10-11,14H2,1H3,(H,26,34)(H,27,33)	ZZPZTQIZEUBASL-UHFFFAOYSA-N	318837	US10517872, Compound 14::US9624246, Compound 14	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318837&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470003	384222126							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
623031	Cc1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc(CCn2n1)c4)c3	InChI=1S/C24H21N5O2/c1-16-12-22-25-24(31)20-7-3-5-18(14-20)15-29-23(30)9-8-21(27-29)19-6-2-4-17(13-19)10-11-28(22)26-16/h2-9,12-14H,10-11,15H2,1H3,(H,25,31)	SANOXDVEBDNEDL-UHFFFAOYSA-N	318838	US10517872, Compound 15::US9624246, Compound 15	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2DF6T92		aid1796601	US9624246	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318838&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			137138406	384222127							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687658	Cn1cc(cn1)-c1cccc(c1)-c1ccc(cn1)-c1cnn(c1)C1CCNCC1	InChI=1S/C23H24N6/c1-28-15-20(13-26-28)17-3-2-4-18(11-17)23-6-5-19(12-25-23)21-14-27-29(16-21)22-7-9-24-10-8-22/h2-6,11-16,22,24H,7-10H2,1H3	GKZVYYXTCYAQFF-UHFFFAOYSA-N	347795	US9790221, Compound 1	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347795&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347786	386049568							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687660	Cn1cc(cn1)-c1cccc(n1)-c1ccc(cn1)-c1cnn(c1)C1CCNCC1	InChI=1S/C22H23N7/c1-28-14-18(13-25-28)20-3-2-4-22(27-20)21-6-5-16(11-24-21)17-12-26-29(15-17)19-7-9-23-10-8-19/h2-6,11-15,19,23H,7-10H2,1H3	RGDBMDNMSAABFJ-UHFFFAOYSA-N	347796	US9790221, Compound 2	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347796&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347782	386049569							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687662	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCN(C2)C(=O)OC(C)(C)C)n1	InChI=1S/C29H36N8O2/c1-29(2,3)39-28(38)37-11-7-8-20(17-37)13-30-27-25(24-15-33-36(5)19-24)16-31-26(34-27)22-10-6-9-21(12-22)23-14-32-35(4)18-23/h6,9-10,12,14-16,18-20H,7-8,11,13,17H2,1-5H3,(H,30,31,34)	BMRQURVCOLLRFY-UHFFFAOYSA-N	347797	US9790221, Compound 3	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347797&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347772	386049570							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687664	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCNC2)n1	InChI=1S/C24H28N8/c1-31-15-20(12-28-31)18-6-3-7-19(9-18)23-27-14-22(21-13-29-32(2)16-21)24(30-23)26-11-17-5-4-8-25-10-17/h3,6-7,9,12-17,25H,4-5,8,10-11H2,1-2H3,(H,26,27,30)	LGIIEKJRZVRBKX-UHFFFAOYSA-N	347798	US9790221, Compound 4	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347798&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347751	386049571							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687666	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCCC(CNC(=O)OC(C)(C)C)C1	InChI=1S/C29H36N8O2/c1-29(2,3)39-28(38)31-13-20-8-7-11-37(17-20)27-25(24-15-33-36(5)19-24)16-30-26(34-27)22-10-6-9-21(12-22)23-14-32-35(4)18-23/h6,9-10,12,14-16,18-20H,7-8,11,13,17H2,1-5H3,(H,31,38)	NJJYQSWBGSKNFI-UHFFFAOYSA-N	347799	US9790221, Compound 5	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347799&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347775	386049572							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687668	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCCC(CN)C1	InChI=1S/C24H28N8/c1-30-15-20(11-27-30)18-6-3-7-19(9-18)23-26-13-22(21-12-28-31(2)16-21)24(29-23)32-8-4-5-17(10-25)14-32/h3,6-7,9,11-13,15-17H,4-5,8,10,14,25H2,1-2H3	DTZYAFMGDRDSEF-UHFFFAOYSA-N	347800	US9790221, Compound 6	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347800&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347864	386049573							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687670	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCNCC2)n1	InChI=1S/C24H28N8/c1-31-15-20(12-28-31)18-4-3-5-19(10-18)23-27-14-22(21-13-29-32(2)16-21)24(30-23)26-11-17-6-8-25-9-7-17/h3-5,10,12-17,25H,6-9,11H2,1-2H3,(H,26,27,30)	AIYIKSZSMWXXLB-UHFFFAOYSA-N	347801	US9790221, Compound 7	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347801&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347739	386049574							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687672	Cn1ccc(n1)-c1cnc(nc1OCC1CCCCO1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N6O2/c1-29-10-9-22(28-29)21-14-25-23(27-24(21)32-16-20-8-3-4-11-31-20)18-7-5-6-17(12-18)19-13-26-30(2)15-19/h5-7,9-10,12-15,20H,3-4,8,11,16H2,1-2H3	SPTUHLMGDHFMEU-UHFFFAOYSA-N	347802	US9790221, Compound 8	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347802&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347789	386049575							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687674	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(OCC2(C)COC2)n1	InChI=1S/C23H24N6O2/c1-23(13-30-14-23)15-31-22-20(19-9-26-29(3)12-19)10-24-21(27-22)17-6-4-5-16(7-17)18-8-25-28(2)11-18/h4-12H,13-15H2,1-3H3	JFRAUNNPKQTZOA-UHFFFAOYSA-N	347803	US9790221, Compound 9	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347803&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347774	386049576							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687676	Cn1ccc(n1)-c1cnc(nc1NCC1CCCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8/c1-31-10-8-22(30-31)21-15-27-23(29-24(21)26-13-17-5-4-9-25-12-17)19-7-3-6-18(11-19)20-14-28-32(2)16-20/h3,6-8,10-11,14-17,25H,4-5,9,12-13H2,1-2H3,(H,26,27,29)	VLQGQOAWWLQXOZ-UHFFFAOYSA-N	347804	US9790221, Compound 10	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347804&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347868	386049577							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687678	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(OCC2COC2)n1	InChI=1S/C22H22N6O2/c1-27-10-18(7-24-27)16-4-3-5-17(6-16)21-23-9-20(19-8-25-28(2)11-19)22(26-21)30-14-15-12-29-13-15/h3-11,15H,12-14H2,1-2H3	YWSVXXZJMDNLAD-UHFFFAOYSA-N	347805	US9790221, Compound 11	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347805&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347796	386049578							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687680	Cn1ccc(n1)-c1cnc(nc1NCC1CCNCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8/c1-31-11-8-22(30-31)21-15-27-23(29-24(21)26-13-17-6-9-25-10-7-17)19-5-3-4-18(12-19)20-14-28-32(2)16-20/h3-5,8,11-12,14-17,25H,6-7,9-10,13H2,1-2H3,(H,26,27,29)	LIIVGXYIFFAVPR-UHFFFAOYSA-N	347806	US9790221, Compound 12	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347806&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347877	386049579							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687682	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCOCC2)n1	InChI=1S/C24H27N7O/c1-30-15-20(12-27-30)18-4-3-5-19(10-18)23-26-14-22(21-13-28-31(2)16-21)24(29-23)25-11-17-6-8-32-9-7-17/h3-5,10,12-17H,6-9,11H2,1-2H3,(H,25,26,29)	JYXZRFURTZGRAR-UHFFFAOYSA-N	347807	US9790221, Compound 13	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347807&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347808	386049580							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687684	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCN(CC2)S(C)(=O)=O)n1	InChI=1S/C24H28N8O2S/c1-30-15-19(12-26-30)17-5-4-6-18(11-17)23-25-14-22(20-13-27-31(2)16-20)24(29-23)28-21-7-9-32(10-8-21)35(3,33)34/h4-6,11-16,21H,7-10H2,1-3H3,(H,25,28,29)	DNVKFXDCKNKODH-UHFFFAOYSA-N	347808	US9790221, Compound 14	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347808&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347733	386049581							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687686	CC(C)Nc1nc(ncc1-c1nnc(C)s1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C20H21N7S/c1-12(2)23-19-17(20-26-25-13(3)28-20)10-21-18(24-19)15-7-5-6-14(8-15)16-9-22-27(4)11-16/h5-12H,1-4H3,(H,21,23,24)	YNEYTVBTSABBLP-UHFFFAOYSA-N	347809	US9790221, Compound 15	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347809&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347765	386049582							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687688	CC(C)Nc1nc(ncc1-c1nnc(s1)C(=O)N1CC[C@@H](O)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O2S/c1-14(2)27-21-19(22-29-30-23(35-22)24(34)32-8-7-18(33)13-32)11-25-20(28-21)16-6-4-5-15(9-16)17-10-26-31(3)12-17/h4-6,9-12,14,18,33H,7-8,13H2,1-3H3,(H,25,27,28)/t18-/m1/s1	IUQPAZJLTWMNOZ-GOSISDBHSA-N	347810	US9790221, Compound 16	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347810&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347759	386049583							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687690	Cc1nnc(s1)-c1cnc(nc1NC1CCCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8S/c1-14-28-29-22(31-14)19-12-24-20(27-21(19)26-18-7-4-8-23-11-18)16-6-3-5-15(9-16)17-10-25-30(2)13-17/h3,5-6,9-10,12-13,18,23H,4,7-8,11H2,1-2H3,(H,24,26,27)	HOBBAZIZPRIAGI-UHFFFAOYSA-N	347811	US9790221, Compound 17	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347811&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347708	386049584							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687692	COC(=O)c1nnc(s1)-c1cnc(nc1NC1CCCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H24N8O2S/c1-31-13-16(10-26-31)14-5-3-6-15(9-14)19-25-12-18(21-29-30-22(34-21)23(32)33-2)20(28-19)27-17-7-4-8-24-11-17/h3,5-6,9-10,12-13,17,24H,4,7-8,11H2,1-2H3,(H,25,27,28)	IWLJECYMUNPASG-UHFFFAOYSA-N	347812	US9790221, Compound 18	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347812&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347875	386049585							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687694	COC(=O)c1nnc(s1)-c1cnc(nc1NCC1CNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H22N8O2S/c1-30-12-16(10-26-30)14-4-3-5-15(6-14)18-25-11-17(19(27-18)24-9-13-7-23-8-13)20-28-29-21(33-20)22(31)32-2/h3-6,10-13,23H,7-9H2,1-2H3,(H,24,25,27)	PYNIUBHGKMKVBV-UHFFFAOYSA-N	347813	US9790221, Compound 19	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347813&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347816	386049586							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687696	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2nnc(s2)C(=O)N2CC[C@@H](O)C2)c(NC2CCCNC2)n1	InChI=1S/C26H29N9O2S/c1-34-14-18(11-29-34)16-4-2-5-17(10-16)22-28-13-21(23(31-22)30-19-6-3-8-27-12-19)24-32-33-25(38-24)26(37)35-9-7-20(36)15-35/h2,4-5,10-11,13-14,19-20,27,36H,3,6-9,12,15H2,1H3,(H,28,30,31)/t19?,20-/m1/s1	IRNDZHQEVMLLSR-GFOWMXPYSA-N	347814	US9790221, Compound 20	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347814&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347848	386049587							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687698	CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)N1CC[C@H](O)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H27N7O2S/c1-15(2)28-22-10-21(17-6-4-5-16(9-17)18-11-27-31(3)13-18)26-12-20(22)23-29-30-24(35-23)25(34)32-8-7-19(33)14-32/h4-6,9-13,15,19,33H,7-8,14H2,1-3H3,(H,26,28)/t19-/m0/s1	HUECEENCGGTSJN-IBGZPJMESA-N	347815	US9790221, Compound 21	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347815&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357734	386049588							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687700	CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)N1CC[C@H](O)C1)-c1cccc(n1)-c1cnn(C)c1	InChI=1S/C24H26N8O2S/c1-14(2)27-20-9-21(19-6-4-5-18(28-19)15-10-26-31(3)12-15)25-11-17(20)22-29-30-23(35-22)24(34)32-8-7-16(33)13-32/h4-6,9-12,14,16,33H,7-8,13H2,1-3H3,(H,25,27)/t16-/m0/s1	QDQQVJAKMJJOCH-INIZCTEOSA-N	347816	US9790221, Compound 22	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347816&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357733	386049589							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687702	Cn1cc(cn1)-c1cccc(c1)-c1cc(c(cn1)-c1cnn(c1)C1CCOCC1)C(F)(F)F	InChI=1S/C24H22F3N5O/c1-31-14-18(11-29-31)16-3-2-4-17(9-16)23-10-22(24(25,26)27)21(13-28-23)19-12-30-32(15-19)20-5-7-33-8-6-20/h2-4,9-15,20H,5-8H2,1H3	KPNWQXHBZBTLOB-UHFFFAOYSA-N	347817	US9790221, Compound 23	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347817&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347799	386049590							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687704	Cc1cc(ncc1-c1cnn(c1)C1CCOCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H25N5O/c1-17-10-24(19-5-3-4-18(11-19)20-12-26-28(2)15-20)25-14-23(17)21-13-27-29(16-21)22-6-8-30-9-7-22/h3-5,10-16,22H,6-9H2,1-2H3	VXXIKSAPZAGIIO-UHFFFAOYSA-N	347818	US9790221, Compound 24	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347818&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347855	386049591							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687706	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC(N)=O)n1	InChI=1S/C20H20N8O/c1-27-11-15(7-24-27)13-4-3-5-14(6-13)19-22-9-17(16-8-25-28(2)12-16)20(26-19)23-10-18(21)29/h3-9,11-12H,10H2,1-2H3,(H2,21,29)(H,22,23,26)	ATWHAPQCQVPOPD-UHFFFAOYSA-N	347819	US9790221, Compound 25	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347819&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347784	386049592							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687708	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC(O)=O)n1	InChI=1S/C20H19N7O2/c1-26-11-15(7-23-26)13-4-3-5-14(6-13)19-21-9-17(16-8-24-27(2)12-16)20(25-19)22-10-18(28)29/h3-9,11-12H,10H2,1-2H3,(H,28,29)(H,21,22,25)	SCMUTEFYRYANBB-UHFFFAOYSA-N	347820	US9790221, Compound 26	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347820&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347840	386049593							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687710	Cn1ccc(n1)-c1cnc(nc1NC1CCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H23N7/c1-28-10-9-20(27-28)19-13-23-21(26-22(19)25-18-7-4-8-18)16-6-3-5-15(11-16)17-12-24-29(2)14-17/h3,5-6,9-14,18H,4,7-8H2,1-2H3,(H,23,25,26)	ZBILCKVCHWNZTR-UHFFFAOYSA-N	347821	US9790221, Compound 27	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347821&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347894	386049594							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687712	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC(CN)(CCl)C2)n1	InChI=1S/C24H27ClN8/c1-32-12-18(9-28-32)16-4-3-5-17(6-16)22-27-11-21(19-10-29-33(2)13-19)23(31-22)30-20-7-24(8-20,14-25)15-26/h3-6,9-13,20H,7-8,14-15,26H2,1-2H3,(H,27,30,31)	GNQMVWAIDZQDNV-UHFFFAOYSA-N	347822	US9790221, Compound 28	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347822&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357735	386049595							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687714	Cn1ccc(n1)-c1cnc(nc1NC1CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C21H21N7/c1-27-9-8-19(26-27)18-12-22-20(25-21(18)24-17-6-7-17)15-5-3-4-14(10-15)16-11-23-28(2)13-16/h3-5,8-13,17H,6-7H2,1-2H3,(H,22,24,25)	DWIDRABUKHLNQA-UHFFFAOYSA-N	347823	US9790221, Compound 29	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347823&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357736	386049596							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687716	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC2)n1	InChI=1S/C21H21N7/c1-27-12-16(9-23-27)14-4-3-5-15(8-14)20-22-11-19(17-10-24-28(2)13-17)21(26-20)25-18-6-7-18/h3-5,8-13,18H,6-7H2,1-2H3,(H,22,25,26)	SDMRQHXJQFKDHV-UHFFFAOYSA-N	347824	US9790221, Compound 30	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347824&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357737	386049597							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687718	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC2)n1	InChI=1S/C22H23N7/c1-28-13-17(10-24-28)15-5-3-6-16(9-15)21-23-12-20(18-11-25-29(2)14-18)22(27-21)26-19-7-4-8-19/h3,5-6,9-14,19H,4,7-8H2,1-2H3,(H,23,26,27)	IQMFQXFGETWXJL-UHFFFAOYSA-N	347825	US9790221, Compound 31	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347825&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357738	386049598							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687720	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCCC2)n1	InChI=1S/C23H25N7/c1-29-14-18(11-25-29)16-6-5-7-17(10-16)22-24-13-21(19-12-26-30(2)15-19)23(28-22)27-20-8-3-4-9-20/h5-7,10-15,20H,3-4,8-9H2,1-2H3,(H,24,27,28)	RGKSTZPSBJCACX-UHFFFAOYSA-N	347826	US9790221, Compound 32	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347826&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357739	386049599							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687722	Cn1ccc(n1)-c1cnc(nc1NC1CCCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H25N7/c1-29-11-10-21(28-29)20-14-24-22(27-23(20)26-19-8-3-4-9-19)17-7-5-6-16(12-17)18-13-25-30(2)15-18/h5-7,10-15,19H,3-4,8-9H2,1-2H3,(H,24,26,27)	CTIXZBFOMFMPGZ-UHFFFAOYSA-N	347827	US9790221, Compound 33	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347827&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357742	386049600							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687724	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN)n1	InChI=1S/C20H22N8/c1-27-12-16(9-24-27)14-4-3-5-15(8-14)19-23-11-18(17-10-25-28(2)13-17)20(26-19)22-7-6-21/h3-5,8-13H,6-7,21H2,1-2H3,(H,22,23,26)	YWNDCIFTYAVTGI-UHFFFAOYSA-N	347828	US9790221, Compound 34	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347828&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357743	386049601							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687726	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCO)n1	InChI=1S/C21H23N7O/c1-27-13-17(10-24-27)15-5-3-6-16(9-15)20-23-12-19(18-11-25-28(2)14-18)21(26-20)22-7-4-8-29/h3,5-6,9-14,29H,4,7-8H2,1-2H3,(H,22,23,26)	UTBPPDSKJWJGTI-UHFFFAOYSA-N	347829	US9790221, Compound 35	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347829&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357740	386049602							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687728	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCOCC2)n1	InChI=1S/C24H28N8O/c1-30-16-20(13-27-30)18-4-3-5-19(12-18)23-26-15-22(21-14-28-31(2)17-21)24(29-23)25-6-7-32-8-10-33-11-9-32/h3-5,12-17H,6-11H2,1-2H3,(H,25,26,29)	FYLOTDUPPSAYRS-UHFFFAOYSA-N	347830	US9790221, Compound 36	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347830&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357741	386049603							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687730	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCc2ccncc2)n1	InChI=1S/C24H22N8/c1-31-15-20(12-28-31)18-4-3-5-19(10-18)23-27-14-22(21-13-29-32(2)16-21)24(30-23)26-11-17-6-8-25-9-7-17/h3-10,12-16H,11H2,1-2H3,(H,26,27,30)	YSCNYLZEOKOABL-UHFFFAOYSA-N	347831	US9790221, Compound 37	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347831&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357745	386049604							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687732	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCOC2=O)n1	InChI=1S/C23H24N8O2/c1-29-14-18(11-26-29)16-4-3-5-17(10-16)21-25-13-20(19-12-27-30(2)15-19)22(28-21)24-6-7-31-8-9-33-23(31)32/h3-5,10-15H,6-9H2,1-2H3,(H,24,25,28)	RINBJISAPYEDAA-UHFFFAOYSA-N	347832	US9790221, Compound 38	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347832&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357746	386049605							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687734	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCCC2=O)n1	InChI=1S/C24H26N8O/c1-30-15-19(12-27-30)17-5-3-6-18(11-17)23-26-14-21(20-13-28-31(2)16-20)24(29-23)25-8-10-32-9-4-7-22(32)33/h3,5-6,11-16H,4,7-10H2,1-2H3,(H,25,26,29)	ABEBCQRHEOBPLP-UHFFFAOYSA-N	347833	US9790221, Compound 39	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347833&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357747	386049606							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687736	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCN2CCCC2=O)n1	InChI=1S/C25H28N8O/c1-31-16-20(13-28-31)18-6-3-7-19(12-18)24-27-15-22(21-14-29-32(2)17-21)25(30-24)26-9-5-11-33-10-4-8-23(33)34/h3,6-7,12-17H,4-5,8-11H2,1-2H3,(H,26,27,30)	LEHSYMBQFQWXNR-UHFFFAOYSA-N	347834	US9790221, Compound 40	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347834&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357748	386049607							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687738	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCOC2)n1	InChI=1S/C22H23N7O/c1-28-12-17(9-24-28)15-4-3-5-16(8-15)21-23-11-20(18-10-25-29(2)13-18)22(27-21)26-19-6-7-30-14-19/h3-5,8-13,19H,6-7,14H2,1-2H3,(H,23,26,27)	WMPBJANDRBQKLJ-UHFFFAOYSA-N	347835	US9790221, Compound 41	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347835&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357749	386049608							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687740	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CC(F)(F)C2)n1	InChI=1S/C23H23F2N7/c1-31-13-18(10-28-31)16-4-3-5-17(6-16)21-27-12-20(19-11-29-32(2)14-19)22(30-21)26-9-15-7-23(24,25)8-15/h3-6,10-15H,7-9H2,1-2H3,(H,26,27,30)	FASAXWZUGXWYCH-UHFFFAOYSA-N	347836	US9790221, Compound 42	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347836&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357744	386049609							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687742	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(C)CCC2)n1	InChI=1S/C24H27N7/c1-24(8-5-9-24)16-26-23-21(20-12-28-31(3)15-20)13-25-22(29-23)18-7-4-6-17(10-18)19-11-27-30(2)14-19/h4,6-7,10-15H,5,8-9,16H2,1-3H3,(H,25,26,29)	JZUXTONNGLAGNS-UHFFFAOYSA-N	347837	US9790221, Compound 43	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347837&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357750	386049610							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687744	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CC[C@H](N)CC2)n1	InChI=1S/C24H28N8/c1-31-14-18(11-27-31)16-4-3-5-17(10-16)23-26-13-22(19-12-28-32(2)15-19)24(30-23)29-21-8-6-20(25)7-9-21/h3-5,10-15,20-21H,6-9,25H2,1-2H3,(H,26,29,30)/t20-,21+	HRKWQXXRXVOSOT-OYRHEFFESA-N	347838	US9790221, Compound 44	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347838&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357752	386049611							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687746	CN(CC1(F)COC1)c1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H24FN7O/c1-29(13-23(24)14-32-15-23)22-20(19-9-27-31(3)12-19)10-25-21(28-22)17-6-4-5-16(7-17)18-8-26-30(2)11-18/h4-12H,13-15H2,1-3H3	CVUYMCPYMRJEPD-UHFFFAOYSA-N	347839	US9790221, Compound 45	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347839&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357751	386049612							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687748	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2C[C@H](O)C2)n1	InChI=1S/C22H23N7O/c1-28-12-16(9-24-28)14-4-3-5-15(6-14)21-23-11-20(17-10-25-29(2)13-17)22(27-21)26-18-7-19(30)8-18/h3-6,9-13,18-19,30H,7-8H2,1-2H3,(H,23,26,27)/t18-,19+	RWRVISCWYIIYAX-KDURUIRLSA-N	347840	US9790221, Compound 46	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347840&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357753	386049613							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687750	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2C[C@H](O)C2)n1	InChI=1S/C22H23N7O/c1-28-12-16(9-24-28)14-4-3-5-15(6-14)21-23-11-20(17-10-25-29(2)13-17)22(27-21)26-18-7-19(30)8-18/h3-6,9-13,18-19,30H,7-8H2,1-2H3,(H,23,26,27)/t18-,19-	RWRVISCWYIIYAX-WGSAOQKQSA-N	347841	US9790221, Compound 47	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347841&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357753	386049614							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687752	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC(F)(F)C2)n1	InChI=1S/C22H21F2N7/c1-30-12-16(9-26-30)14-4-3-5-15(6-14)20-25-11-19(17-10-27-31(2)13-17)21(29-20)28-18-7-22(23,24)8-18/h3-6,9-13,18H,7-8H2,1-2H3,(H,25,28,29)	WUGZCFHBTBZAKK-UHFFFAOYSA-N	347842	US9790221, Compound 48	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347842&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357755	386049615							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687754	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2C[C@H](C2)S(C)(=O)=O)n1	InChI=1S/C23H25N7O2S/c1-29-13-17(10-25-29)15-5-4-6-16(7-15)22-24-12-21(18-11-26-30(2)14-18)23(28-22)27-19-8-20(9-19)33(3,31)32/h4-7,10-14,19-20H,8-9H2,1-3H3,(H,24,27,28)/t19-,20+	ZRJZIWDFCSJDNF-BGYRXZFFSA-N	347843	US9790221, Compound 49	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347843&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357757	386049616							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687756	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC(F)C2)n1	InChI=1S/C22H22FN7/c1-29-12-16(9-25-29)14-4-3-5-15(6-14)21-24-11-20(17-10-26-30(2)13-17)22(28-21)27-19-7-18(23)8-19/h3-6,9-13,18-19H,7-8H2,1-2H3,(H,24,27,28)	LKLKMYFYHDFSLS-UHFFFAOYSA-N	347844	US9790221, Compound 50	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347844&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357758	386049617							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687758	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCN2CCOCC2)n1	InChI=1S/C25H30N8O/c1-31-17-21(14-28-31)19-5-3-6-20(13-19)24-27-16-23(22-15-29-32(2)18-22)25(30-24)26-7-4-8-33-9-11-34-12-10-33/h3,5-6,13-18H,4,7-12H2,1-2H3,(H,26,27,30)	LDKDQUHHADIBMB-UHFFFAOYSA-N	347845	US9790221, Compound 51	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347845&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357756	386049618							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687760	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(O)COC2)n1	InChI=1S/C22H23N7O2/c1-28-10-17(7-25-28)15-4-3-5-16(6-15)20-23-9-19(18-8-26-29(2)11-18)21(27-20)24-12-22(30)13-31-14-22/h3-11,30H,12-14H2,1-2H3,(H,23,24,27)	CJAZGMFJTFNQTF-UHFFFAOYSA-N	347846	US9790221, Compound 52	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347846&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357754	386049619							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687762	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(CO)CCC2)n1	InChI=1S/C24H27N7O/c1-30-13-19(10-27-30)17-5-3-6-18(9-17)22-25-12-21(20-11-28-31(2)14-20)23(29-22)26-15-24(16-32)7-4-8-24/h3,5-6,9-14,32H,4,7-8,15-16H2,1-2H3,(H,25,26,29)	KCKPZBIPGDQIND-UHFFFAOYSA-N	347847	US9790221, Compound 53	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347847&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357759	386049620							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687764	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H](O)CO)n1	InChI=1S/C21H23N7O2/c1-27-11-16(7-24-27)14-4-3-5-15(6-14)20-23-10-19(17-8-25-28(2)12-17)21(26-20)22-9-18(30)13-29/h3-8,10-12,18,29-30H,9,13H2,1-2H3,(H,22,23,26)/t18-/m0/s1	WWNTVVYKRQBYEQ-SFHVURJKSA-N	347848	US9790221, Compound 54	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347848&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357760	386049621							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687766	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCS(=O)(=O)CC2)n1	InChI=1S/C24H28N8O2S/c1-30-16-20(13-27-30)18-4-3-5-19(12-18)23-26-15-22(21-14-28-31(2)17-21)24(29-23)25-6-7-32-8-10-35(33,34)11-9-32/h3-5,12-17H,6-11H2,1-2H3,(H,25,26,29)	AAZZPIVKPGOXMK-UHFFFAOYSA-N	347849	US9790221, Compound 55	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347849&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357761	386049622							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687768	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@@H](O)CO)n1	InChI=1S/C21H23N7O2/c1-27-11-16(7-24-27)14-4-3-5-15(6-14)20-23-10-19(17-8-25-28(2)12-17)21(26-20)22-9-18(30)13-29/h3-8,10-12,18,29-30H,9,13H2,1-2H3,(H,22,23,26)/t18-/m1/s1	WWNTVVYKRQBYEQ-GOSISDBHSA-N	347850	US9790221, Compound 56	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347850&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357763	386049623							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687770	CC(=O)NCCNc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8O/c1-15(31)23-7-8-24-22-20(19-11-27-30(3)14-19)12-25-21(28-22)17-6-4-5-16(9-17)18-10-26-29(2)13-18/h4-6,9-14H,7-8H2,1-3H3,(H,23,31)(H,24,25,28)	JXSBVAFKVRLTBE-UHFFFAOYSA-N	347851	US9790221, Compound 57	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347851&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360885	386049624							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687772	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCNC2=O)n1	InChI=1S/C23H25N9O/c1-30-14-18(11-27-30)16-4-3-5-17(10-16)21-26-13-20(19-12-28-31(2)15-19)22(29-21)24-6-8-32-9-7-25-23(32)33/h3-5,10-15H,6-9H2,1-2H3,(H,25,33)(H,24,26,29)	XIFSQCAJQIQDIP-UHFFFAOYSA-N	347852	US9790221, Compound 58	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347852&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357959	386049625							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687774	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CNCCO2)n1	InChI=1S/C23H26N8O/c1-30-14-18(9-27-30)16-4-3-5-17(8-16)22-26-13-21(19-10-28-31(2)15-19)23(29-22)25-12-20-11-24-6-7-32-20/h3-5,8-10,13-15,20,24H,6-7,11-12H2,1-2H3,(H,25,26,29)	BITLDNRLVOIKSQ-UHFFFAOYSA-N	347853	US9790221, Compound 59	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347853	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347853&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357762	386049626							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687776	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC(=O)NC2)n1	InChI=1S/C23H24N8O/c1-30-13-17(9-26-30)15-4-3-5-16(8-15)22-25-12-20(18-10-27-31(2)14-18)23(29-22)28-19-6-7-21(32)24-11-19/h3-5,8-10,12-14,19H,6-7,11H2,1-2H3,(H,24,32)(H,25,28,29)/t19-/m0/s1	PIJSHCDNEZVWMX-IBGZPJMESA-N	347854	US9790221, Compound 60	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347854	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347854&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357764	386049627							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687778	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@@H]2CCC(=O)N2)n1	InChI=1S/C23H24N8O/c1-30-13-17(9-26-30)15-4-3-5-16(8-15)22-25-12-20(18-10-27-31(2)14-18)23(29-22)24-11-19-6-7-21(32)28-19/h3-5,8-10,12-14,19H,6-7,11H2,1-2H3,(H,28,32)(H,24,25,29)/t19-/m0/s1	UYRUQSJFNMNBEN-IBGZPJMESA-N	347855	US9790221, Compound 61	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347855&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357765	386049628							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687780	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2C[C@H](N)C2)n1	InChI=1S/C22H24N8/c1-29-12-16(9-25-29)14-4-3-5-15(6-14)21-24-11-20(17-10-26-30(2)13-17)22(28-21)27-19-7-18(23)8-19/h3-6,9-13,18-19H,7-8,23H2,1-2H3,(H,24,27,28)/t18-,19+	NRQLGEWVVODBQU-KDURUIRLSA-N	347856	US9790221, Compound 62	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347856	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347856&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357766	386049629							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687782	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2COC2)n1	InChI=1S/C22H23N7O/c1-28-11-18(8-25-28)16-4-3-5-17(6-16)21-24-10-20(19-9-26-29(2)12-19)22(27-21)23-7-15-13-30-14-15/h3-6,8-12,15H,7,13-14H2,1-2H3,(H,23,24,27)	WQIRIBWOZRJVTK-UHFFFAOYSA-N	347857	US9790221, Compound 63	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347857&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357768	386049630							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687784	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CCNC2)n1	InChI=1S/C23H26N8/c1-30-14-19(11-27-30)17-4-3-5-18(8-17)22-26-13-21(20-12-28-31(2)15-20)23(29-22)25-10-16-6-7-24-9-16/h3-5,8,11-16,24H,6-7,9-10H2,1-2H3,(H,25,26,29)/t16-/m0/s1	FBDUIWWBUPBMON-INIZCTEOSA-N	347858	US9790221, Compound 64	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347858&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357767	386049631							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687786	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3(CC(N)C3)C2)n1	InChI=1S/C25H28N8/c1-32-14-18(11-28-32)16-4-3-5-17(6-16)23-27-13-22(19-12-29-33(2)15-19)24(31-23)30-21-9-25(10-21)7-20(26)8-25/h3-6,11-15,20-21H,7-10,26H2,1-2H3,(H,27,30,31)	YRWFHFFBWIAAFJ-UHFFFAOYSA-N	347859	US9790221, Compound 65	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347859&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357769	386049632							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687788	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CC(N)(C2)CC3)n1	InChI=1S/C24H26N8/c1-31-12-18(9-27-31)16-4-3-5-17(8-16)21-26-11-20(19-10-28-32(2)13-19)22(29-21)30-24-7-6-23(25,14-24)15-24/h3-5,8-13H,6-7,14-15,25H2,1-2H3,(H,26,29,30)	URLNTVKUVIIYOT-UHFFFAOYSA-N	347860	US9790221, Compound 66	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347860&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357770	386049633							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687790	Cn1ccc(n1)-c1cnc(nc1NCCCN1CCOC1=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O2/c1-30-10-7-21(29-30)20-15-26-22(18-6-3-5-17(13-18)19-14-27-31(2)16-19)28-23(20)25-8-4-9-32-11-12-34-24(32)33/h3,5-7,10,13-16H,4,8-9,11-12H2,1-2H3,(H,25,26,28)	QROSHQMASSQXLG-UHFFFAOYSA-N	347861	US9790221, Compound 67	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347861&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357771	386049634							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687792	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2ccn(C)n2)c(NCCCO)n1	InChI=1S/C21H23N7O/c1-27-9-7-19(26-27)18-13-23-20(25-21(18)22-8-4-10-29)16-6-3-5-15(11-16)17-12-24-28(2)14-17/h3,5-7,9,11-14,29H,4,8,10H2,1-2H3,(H,22,23,25)	JMXOXQDPNWCGKA-UHFFFAOYSA-N	347862	US9790221, Compound 68	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347862&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357772	386049635							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687794	Cn1ccc(n1)-c1cnc(nc1NCCN1CCOCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O/c1-30-8-6-22(29-30)21-16-26-23(28-24(21)25-7-9-32-10-12-33-13-11-32)19-5-3-4-18(14-19)20-15-27-31(2)17-20/h3-6,8,14-17H,7,9-13H2,1-2H3,(H,25,26,28)	TUZXJOVLOLKUAS-UHFFFAOYSA-N	347863	US9790221, Compound 69	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347863&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357774	386049636							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687796	Cn1ccc(n1)-c1cnc(nc1NCCN1CCCC1=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O/c1-30-11-8-21(29-30)20-15-26-23(28-24(20)25-9-12-32-10-4-7-22(32)33)18-6-3-5-17(13-18)19-14-27-31(2)16-19/h3,5-6,8,11,13-16H,4,7,9-10,12H2,1-2H3,(H,25,26,28)	JOLAPAYECRBRCT-UHFFFAOYSA-N	347864	US9790221, Compound 70	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347864&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357773	386049637							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687798	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2ccn(C)n2)c(NCC2(C)CCC2)n1	InChI=1S/C24H27N7/c1-24(9-5-10-24)16-26-23-20(21-8-11-30(2)29-21)14-25-22(28-23)18-7-4-6-17(12-18)19-13-27-31(3)15-19/h4,6-8,11-15H,5,9-10,16H2,1-3H3,(H,25,26,28)	AVKZTTSFWQRQDU-UHFFFAOYSA-N	347865	US9790221, Compound 71	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347865&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357775	386049638							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687800	Cn1ccc(n1)-c1cnc(nc1NCCCN1CCCC1=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8O/c1-31-13-9-22(30-31)21-16-27-24(19-7-3-6-18(14-19)20-15-28-32(2)17-20)29-25(21)26-10-5-12-33-11-4-8-23(33)34/h3,6-7,9,13-17H,4-5,8,10-12H2,1-2H3,(H,26,27,29)	YCAJIYRUJVHXMF-UHFFFAOYSA-N	347866	US9790221, Compound 72	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347866&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357776	386049639							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687802	CC(=O)NCCNc1nc(ncc1-c1ccn(C)n1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8O/c1-15(31)23-8-9-24-22-19(20-7-10-29(2)28-20)13-25-21(27-22)17-6-4-5-16(11-17)18-12-26-30(3)14-18/h4-7,10-14H,8-9H2,1-3H3,(H,23,31)(H,24,25,27)	JFBRUAXXSYEOLC-UHFFFAOYSA-N	347867	US9790221, Compound 73	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347867&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360796	386049640							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687804	Cn1ccc(n1)-c1cnc(nc1NCC1CCNC(=O)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O/c1-31-9-7-21(30-31)20-14-27-23(29-24(20)26-12-16-6-8-25-22(33)10-16)18-5-3-4-17(11-18)19-13-28-32(2)15-19/h3-5,7,9,11,13-16H,6,8,10,12H2,1-2H3,(H,25,33)(H,26,27,29)	REUJIPZFDHQZPO-UHFFFAOYSA-N	347868	US9790221, Compound 74	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347868&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357777	386049641							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687806	Cn1ccc(n1)-c1cnc(nc1NCCCN1CCOCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H30N8O/c1-31-10-7-23(30-31)22-17-27-24(20-6-3-5-19(15-20)21-16-28-32(2)18-21)29-25(22)26-8-4-9-33-11-13-34-14-12-33/h3,5-7,10,15-18H,4,8-9,11-14H2,1-2H3,(H,26,27,29)	XHQNKLLJDTUUAT-UHFFFAOYSA-N	347869	US9790221, Compound 75	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347869&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357778	386049642							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687808	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCNC(=O)C2)n1	InChI=1S/C24H26N8O/c1-31-14-19(11-28-31)17-4-3-5-18(9-17)23-27-13-21(20-12-29-32(2)15-20)24(30-23)26-10-16-6-7-25-22(33)8-16/h3-5,9,11-16H,6-8,10H2,1-2H3,(H,25,33)(H,26,27,30)	HEHXPMPYWMGQIZ-UHFFFAOYSA-N	347870	US9790221, Compound 76	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347870&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357779	386049643							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687810	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2[C@@H]3CNC[C@H]23)n1	InChI=1S/C24H26N8/c1-31-13-17(7-28-31)15-4-3-5-16(6-15)23-26-11-19(18-8-29-32(2)14-18)24(30-23)27-12-22-20-9-25-10-21(20)22/h3-8,11,13-14,20-22,25H,9-10,12H2,1-2H3,(H,26,27,30)/t20-,21+,22?	BYLPPMPGCUCXGL-CBQGHPETSA-N	347871	US9790221, Compound 77	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347871&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357780	386049644							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687812	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCN2CCOC2=O)n1	InChI=1S/C24H26N8O2/c1-30-15-19(12-27-30)17-5-3-6-18(11-17)22-26-14-21(20-13-28-31(2)16-20)23(29-22)25-7-4-8-32-9-10-34-24(32)33/h3,5-6,11-16H,4,7-10H2,1-2H3,(H,25,26,29)	LRXNHBHLNKIDMX-UHFFFAOYSA-N	347872	US9790221, Compound 78	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347872&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357781	386049645							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687814	Cn1ccc(n1)-c1cnc(nc1N[C@H]1C[C@H](C1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H25N7O2S/c1-29-8-7-21(28-29)20-13-24-22(27-23(20)26-18-10-19(11-18)33(3,31)32)16-6-4-5-15(9-16)17-12-25-30(2)14-17/h4-9,12-14,18-19H,10-11H2,1-3H3,(H,24,26,27)/t18-,19+	BTHHTUIURXXDQK-KDURUIRLSA-N	347873	US9790221, Compound 79	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347873&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357782	386049646							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687816	Cn1ccc(n1)-c1cnc(nc1NC1CC(F)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H22FN7/c1-29-7-6-20(28-29)19-12-24-21(27-22(19)26-18-9-17(23)10-18)15-5-3-4-14(8-15)16-11-25-30(2)13-16/h3-8,11-13,17-18H,9-10H2,1-2H3,(H,24,26,27)	WFBOEOGRFCZVGH-UHFFFAOYSA-N	347874	US9790221, Compound 80	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347874&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357784	386049647							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687818	Cn1ccc(n1)-c1cnc(nc1NCC1CC(F)(F)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H23F2N7/c1-31-7-6-20(30-31)19-13-27-21(29-22(19)26-11-15-9-23(24,25)10-15)17-5-3-4-16(8-17)18-12-28-32(2)14-18/h3-8,12-15H,9-11H2,1-2H3,(H,26,27,29)	MQYHEQOTZHHFLI-UHFFFAOYSA-N	347875	US9790221, Compound 81	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347875&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357783	386049648							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687820	Cn1ccc(n1)-c1cnc(nc1NC1CC(O)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H23N7O/c1-28-7-6-20(27-28)19-12-23-21(26-22(19)25-17-9-18(30)10-17)15-5-3-4-14(8-15)16-11-24-29(2)13-16/h3-8,11-13,17-18,30H,9-10H2,1-2H3,(H,23,25,26)	BFKVITYKFXIVEL-UHFFFAOYSA-N	347876	US9790221, Compound 82	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347876&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357785	386049649							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687822	Cn1ccc(n1)-c1cnc(nc1NC[C@@H](O)CO)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C21H23N7O2/c1-27-7-6-19(26-27)18-11-23-20(25-21(18)22-10-17(30)13-29)15-5-3-4-14(8-15)16-9-24-28(2)12-16/h3-9,11-12,17,29-30H,10,13H2,1-2H3,(H,22,23,25)/t17-/m1/s1	ZXICHULZXNAPKS-QGZVFWFLSA-N	347877	US9790221, Compound 83	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347877&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357786	386049650							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687824	Cn1ccc(n1)-c1cnc(nc1NCCN1CCS(=O)(=O)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O2S/c1-30-8-6-22(29-30)21-16-26-23(19-5-3-4-18(14-19)20-15-27-31(2)17-20)28-24(21)25-7-9-32-10-12-35(33,34)13-11-32/h3-6,8,14-17H,7,9-13H2,1-2H3,(H,25,26,28)	SKBCOTMUGSFDHK-UHFFFAOYSA-N	347878	US9790221, Compound 84	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347878&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357787	386049651							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687826	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC2CCNC2)n1	InChI=1S/C24H28N8/c1-31-15-20(12-28-31)18-4-3-5-19(10-18)23-27-14-22(21-13-29-32(2)16-21)24(30-23)26-9-7-17-6-8-25-11-17/h3-5,10,12-17,25H,6-9,11H2,1-2H3,(H,26,27,30)	QXSGPHDMZQVGLJ-UHFFFAOYSA-N	347879	US9790221, Compound 85	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347879&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357788	386049652							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687828	CN1C(=O)CC[C@]11CC[C@@H](CC1)n1cc(cn1)-c1cnc(nc1NCC1CCNCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C33H41N9O/c1-40-21-26(18-37-40)24-4-3-5-25(16-24)31-36-20-29(32(39-31)35-17-23-9-14-34-15-10-23)27-19-38-42(22-27)28-6-11-33(12-7-28)13-8-30(43)41(33)2/h3-5,16,18-23,28,34H,6-15,17H2,1-2H3,(H,35,36,39)/t28-,33+	GZFJWPAKTFWNOW-HWFQPFARSA-N	347880	US9790221, Compound 86	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347880&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347812	386049653							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687830	CN1C(=O)CC[C@]11CC[C@@H](CC1)n1cc(cn1)-c1cnc(nc1NCC1CCN(C)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C34H43N9O/c1-40-15-10-24(11-16-40)18-35-33-30(21-36-32(39-33)26-6-4-5-25(17-26)27-19-37-41(2)22-27)28-20-38-43(23-28)29-7-12-34(13-8-29)14-9-31(44)42(34)3/h4-6,17,19-24,29H,7-16,18H2,1-3H3,(H,35,36,39)/t29-,34+	FOTBDVFUZHABEA-DEAKIZSRSA-N	347881	US9790221, Compound 87	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347881&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347762	386049654							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687832	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCCN)n1	InChI=1S/C22H26N8/c1-29-14-18(11-26-29)16-6-5-7-17(10-16)21-25-13-20(19-12-27-30(2)15-19)22(28-21)24-9-4-3-8-23/h5-7,10-15H,3-4,8-9,23H2,1-2H3,(H,24,25,28)	CHGPWWZYDWIDOE-UHFFFAOYSA-N	347882	US9790221, Compound 88	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347882&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357789	386049655							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687834	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCN)n1	InChI=1S/C21H24N8/c1-28-13-17(10-25-28)15-5-3-6-16(9-15)20-24-12-19(18-11-26-29(2)14-18)21(27-20)23-8-4-7-22/h3,5-6,9-14H,4,7-8,22H2,1-2H3,(H,23,24,27)	KFFGSVASBDECCS-UHFFFAOYSA-N	347883	US9790221, Compound 89	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347883&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357790	386049656							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687836	Cn1ccc(n1)-c1cnc(nc1NC1CC(F)(F)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H21F2N7/c1-30-7-6-19(29-30)18-12-25-20(28-21(18)27-17-9-22(23,24)10-17)15-5-3-4-14(8-15)16-11-26-31(2)13-16/h3-8,11-13,17H,9-10H2,1-2H3,(H,25,27,28)	AWDSDQZZQPXLTB-UHFFFAOYSA-N	347884	US9790221, Compound 90	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347884&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357791	386049657							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687838	Cn1ccc(n1)-c1cnc(nc1NCCN1CCOC1=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H24N8O2/c1-29-8-6-20(28-29)19-14-25-21(27-22(19)24-7-9-31-10-11-33-23(31)32)17-5-3-4-16(12-17)18-13-26-30(2)15-18/h3-6,8,12-15H,7,9-11H2,1-2H3,(H,24,25,27)	FBIXIIALDQFJIC-UHFFFAOYSA-N	347885	US9790221, Compound 91	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347885&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357792	386049658							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687840	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2(CO)COC2)n1	InChI=1S/C22H23N7O2/c1-28-10-17(7-24-28)15-4-3-5-16(6-15)20-23-9-19(18-8-25-29(2)11-18)21(26-20)27-22(12-30)13-31-14-22/h3-11,30H,12-14H2,1-2H3,(H,23,26,27)	VDJZDCKYHSEFFA-UHFFFAOYSA-N	347886	US9790221, Compound 92	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347886&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357793	386049659							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687842	Cn1ccc(n1)-c1cnc(nc1NC1(CO)COC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H23N7O2/c1-28-7-6-19(27-28)18-10-23-20(25-21(18)26-22(12-30)13-31-14-22)16-5-3-4-15(8-16)17-9-24-29(2)11-17/h3-11,30H,12-14H2,1-2H3,(H,23,25,26)	KCWAZKNCGYPBLB-UHFFFAOYSA-N	347887	US9790221, Compound 93	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347887&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357794	386049660							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687844	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@@H]2O)n1	InChI=1S/C23H25N7O/c1-29-13-17(10-25-29)15-5-3-6-16(9-15)22-24-12-19(18-11-26-30(2)14-18)23(28-22)27-20-7-4-8-21(20)31/h3,5-6,9-14,20-21,31H,4,7-8H2,1-2H3,(H,24,27,28)/t20-,21-/m0/s1	UZXZVYGDNUGMGM-SFTDATJTSA-N	347888	US9790221, Compound 94	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347888&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357795	386049661							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687846	Cn1ccc(n1)-c1cnc(nc1N[C@H]1CCC[C@@H]1O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H25N7O/c1-29-10-9-19(28-29)18-13-24-22(27-23(18)26-20-7-4-8-21(20)31)16-6-3-5-15(11-16)17-12-25-30(2)14-17/h3,5-6,9-14,20-21,31H,4,7-8H2,1-2H3,(H,24,26,27)/t20-,21-/m0/s1	SQDDKYMMDDUSDL-SFTDATJTSA-N	347889	US9790221, Compound 95	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347889&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357802	386049662							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687848	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCO)n1	InChI=1S/C20H21N7O/c1-26-12-16(9-23-26)14-4-3-5-15(8-14)19-22-11-18(17-10-24-27(2)13-17)20(25-19)21-6-7-28/h3-5,8-13,28H,6-7H2,1-2H3,(H,21,22,25)	DGUBRTGREJISCA-UHFFFAOYSA-N	347890	US9790221, Compound 96	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347890&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357796	386049663							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687850	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2ccn(C)n2)c(NCCCCO)n1	InChI=1S/C22H25N7O/c1-28-10-8-20(27-28)19-14-24-21(26-22(19)23-9-3-4-11-30)17-7-5-6-16(12-17)18-13-25-29(2)15-18/h5-8,10,12-15,30H,3-4,9,11H2,1-2H3,(H,23,24,26)	NCYQWMIDVYIEBP-UHFFFAOYSA-N	347891	US9790221, Compound 97	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347891	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347891&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357797	386049664							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687852	Cn1ccc(n1)-c1cnc(nc1NC1CC2(CC(N)C2)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8/c1-32-7-6-22(31-32)21-14-27-23(17-5-3-4-16(8-17)18-13-28-33(2)15-18)30-24(21)29-20-11-25(12-20)9-19(26)10-25/h3-8,13-15,19-20H,9-12,26H2,1-2H3,(H,27,29,30)	JJENVQFBWBTJJM-UHFFFAOYSA-N	347892	US9790221, Compound 98	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347892	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347892&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357799	386049665							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687854	Cn1ccc(n1)-c1cnc(nc1NC1CC(CN)(CCl)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H27ClN8/c1-32-7-6-21(31-32)20-12-27-22(30-23(20)29-19-9-24(10-19,14-25)15-26)17-5-3-4-16(8-17)18-11-28-33(2)13-18/h3-8,11-13,19H,9-10,14-15,26H2,1-2H3,(H,27,29,30)	DVPWGCAKPXSNCJ-UHFFFAOYSA-N	347893	US9790221, Compound 99	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347893	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347893&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357798	386049666							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687856	Cn1ccc(n1)-c1cnc(nc1NCCO)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C20H21N7O/c1-26-8-6-18(25-26)17-12-22-19(24-20(17)21-7-9-28)15-5-3-4-14(10-15)16-11-23-27(2)13-16/h3-6,8,10-13,28H,7,9H2,1-2H3,(H,21,22,24)	PYAJWDOIFFNWNH-UHFFFAOYSA-N	347894	US9790221, Compound 100	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347894&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357800	386049667							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687858	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCCO)n1	InChI=1S/C22H25N7O/c1-28-14-18(11-25-28)16-6-5-7-17(10-16)21-24-13-20(19-12-26-29(2)15-19)22(27-21)23-8-3-4-9-30/h5-7,10-15,30H,3-4,8-9H2,1-2H3,(H,23,24,27)	VIZDMWWTLIKWGI-UHFFFAOYSA-N	347895	US9790221, Compound 101	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347895	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347895&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357801	386049668							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687860	Cn1ccc(n1)-c1cnc(nc1NC1CCC(=O)NC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H24N8O/c1-30-9-8-20(29-30)19-13-25-22(28-23(19)27-18-6-7-21(32)24-12-18)16-5-3-4-15(10-16)17-11-26-31(2)14-17/h3-5,8-11,13-14,18H,6-7,12H2,1-2H3,(H,24,32)(H,25,27,28)	BPDPAYRDHBVEAV-UHFFFAOYSA-N	347896	US9790221, Compound 102	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347896	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347896&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357807	386049669							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687862	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC(=O)NC2)n1	InChI=1S/C23H24N8O/c1-30-13-17(9-26-30)15-4-3-5-16(8-15)22-25-12-20(18-10-27-31(2)14-18)23(29-22)28-19-6-7-21(32)24-11-19/h3-5,8-10,12-14,19H,6-7,11H2,1-2H3,(H,24,32)(H,25,28,29)	PIJSHCDNEZVWMX-UHFFFAOYSA-N	347897	US9790221, Compound 103	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347897&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357803	386049670							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687864	Cn1ccc(n1)-c1cnc(nc1NC[C@H]1CCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8/c1-30-9-7-21(29-30)20-14-26-22(28-23(20)25-12-16-6-8-24-11-16)18-5-3-4-17(10-18)19-13-27-31(2)15-19/h3-5,7,9-10,13-16,24H,6,8,11-12H2,1-2H3,(H,25,26,28)/t16-/m0/s1	BORFUWYMIJRVOF-INIZCTEOSA-N	347898	US9790221, Compound 104	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347898	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347898&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357806	386049671							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687866	CN1CCOC(CNc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)C1	InChI=1S/C24H28N8O/c1-30-7-8-33-21(16-30)12-25-24-22(20-11-28-32(3)15-20)13-26-23(29-24)18-6-4-5-17(9-18)19-10-27-31(2)14-19/h4-6,9-11,13-15,21H,7-8,12,16H2,1-3H3,(H,25,26,29)	OVSBUHZVZDQGES-UHFFFAOYSA-N	347899	US9790221, Compound 105	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347899	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347899&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357805	386049672							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687868	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2nnc(s2)C(=O)N2CC[C@@H](O)C2)c(NCC2CNC2)n1	InChI=1S/C25H27N9O2S/c1-33-13-18(11-29-33)16-3-2-4-17(7-16)21-28-12-20(22(30-21)27-10-15-8-26-9-15)23-31-32-24(37-23)25(36)34-6-5-19(35)14-34/h2-4,7,11-13,15,19,26,35H,5-6,8-10,14H2,1H3,(H,27,28,30)/t19-/m1/s1	VTUODBRBWHKXAG-LJQANCHMSA-N	347900	US9790221, Compound 106	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347900	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347900&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357804	386049673							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687870	Cn1ccc(n1)-c1cnc(nc1N[C@@H]1CC[C@H](N)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8/c1-30-9-8-21(29-30)20-13-25-22(28-23(20)27-19-7-6-18(24)11-19)16-5-3-4-15(10-16)17-12-26-31(2)14-17/h3-5,8-10,12-14,18-19H,6-7,11,24H2,1-2H3,(H,25,27,28)/t18-,19+/m0/s1	RPMCQWGLLTVGAY-RBUKOAKNSA-N	347901	US9790221, Compound 107	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347901	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347901&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357808	386049674							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687872	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CC[C@H](N)C2)n1	InChI=1S/C23H26N8/c1-30-13-17(10-26-30)15-4-3-5-16(8-15)22-25-12-21(18-11-27-31(2)14-18)23(29-22)28-20-7-6-19(24)9-20/h3-5,8,10-14,19-20H,6-7,9,24H2,1-2H3,(H,25,28,29)/t19-,20+/m0/s1	UABWFXULANPTAV-VQTJNVASSA-N	347902	US9790221, Compound 108	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347902	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347902&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357809	386049675							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687874	CC(=O)NCCCNc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8O/c1-16(32)24-8-5-9-25-23-21(20-12-28-31(3)15-20)13-26-22(29-23)18-7-4-6-17(10-18)19-11-27-30(2)14-19/h4,6-7,10-15H,5,8-9H2,1-3H3,(H,24,32)(H,25,26,29)	NBOIOHHVHAPORR-UHFFFAOYSA-N	347903	US9790221, Compound 109	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347903&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357810	386049676							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687876	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCN2CCC(O)CC2)n1	InChI=1S/C25H30N8O/c1-31-16-20(13-28-31)18-4-3-5-19(12-18)24-27-15-23(21-14-29-32(2)17-21)25(30-24)26-8-11-33-9-6-22(34)7-10-33/h3-5,12-17,22,34H,6-11H2,1-2H3,(H,26,27,30)	SVAIUGXLBAPZEZ-UHFFFAOYSA-N	347904	US9790221, Compound 110	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347904&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357811	386049677							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687878	Cn1ccc(n1)-c1cnc(nc1N[C@@H]1CC[C@H](N)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8/c1-31-11-10-22(30-31)21-14-26-23(29-24(21)28-20-8-6-19(25)7-9-20)17-5-3-4-16(12-17)18-13-27-32(2)15-18/h3-5,10-15,19-20H,6-9,25H2,1-2H3,(H,26,28,29)/t19-,20+	SQKCJZMLLYDNDV-BGYRXZFFSA-N	347905	US9790221, Compound 111	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347905&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357812	386049678							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687880	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(O)CCNCC2(C)C)n1	InChI=1S/C26H32N8O/c1-25(2)16-27-9-8-26(25,35)17-29-24-22(21-12-31-34(4)15-21)13-28-23(32-24)19-7-5-6-18(10-19)20-11-30-33(3)14-20/h5-7,10-15,27,35H,8-9,16-17H2,1-4H3,(H,28,29,32)	GZXRQRCTEBICGP-UHFFFAOYSA-N	347906	US9790221, Compound 112	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347906&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357813	386049679							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687882	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CNC[C@H]2O)n1	InChI=1S/C22H24N8O/c1-29-12-16(7-25-29)14-4-3-5-15(6-14)21-24-9-18(17-8-26-30(2)13-17)22(28-21)27-19-10-23-11-20(19)31/h3-9,12-13,19-20,23,31H,10-11H2,1-2H3,(H,24,27,28)/t19-,20-/m1/s1	GDGGJEQTJDVTTG-WOJBJXKFSA-N	347907	US9790221, Compound 113	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347907&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357815	386049680							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687884	Cn1ccc(n1)-c1cnc(nc1NCC1(O)CCNCC1(C)C)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C26H32N8O/c1-25(2)16-27-10-9-26(25,35)17-29-24-21(22-8-11-33(3)32-22)14-28-23(31-24)19-7-5-6-18(12-19)20-13-30-34(4)15-20/h5-8,11-15,27,35H,9-10,16-17H2,1-4H3,(H,28,29,31)	OODSWQOLNQOOEK-UHFFFAOYSA-N	347908	US9790221, Compound 114	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347908&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357814	386049681							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687886	Cn1ccc(n1)-c1cnc(nc1NCC1CNCCO1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8O/c1-30-8-6-21(29-30)20-14-26-22(28-23(20)25-13-19-12-24-7-9-32-19)17-5-3-4-16(10-17)18-11-27-31(2)15-18/h3-6,8,10-11,14-15,19,24H,7,9,12-13H2,1-2H3,(H,25,26,28)	GEFOLSFVVAUQDX-UHFFFAOYSA-N	347909	US9790221, Compound 115	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347909&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357816	386049682							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687888	Cn1ccc(n1)-c1cnc(nc1NC[C@H]1CCNC[C@H]1O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O/c1-31-9-7-21(30-31)20-13-27-23(29-24(20)26-11-18-6-8-25-14-22(18)33)17-5-3-4-16(10-17)19-12-28-32(2)15-19/h3-5,7,9-10,12-13,15,18,22,25,33H,6,8,11,14H2,1-2H3,(H,26,27,29)/t18-,22-/m1/s1	JCJYOVXKIJNIKS-XMSQKQJNSA-N	347910	US9790221, Compound 116	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347910&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357817	386049683							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687890	Cn1ccc(n1)-c1cnc(nc1N[C@H]1CCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8/c1-29-9-7-20(28-29)19-13-24-21(27-22(19)26-18-6-8-23-12-18)16-5-3-4-15(10-16)17-11-25-30(2)14-17/h3-5,7,9-11,13-14,18,23H,6,8,12H2,1-2H3,(H,24,26,27)/t18-/m0/s1	OKKIGWQBZKTXLY-SFHVURJKSA-N	347911	US9790221, Compound 117	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347911&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357818	386049684							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687892	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(OCC2CCCO2)n1	InChI=1S/C23H24N6O2/c1-28-13-18(10-25-28)16-5-3-6-17(9-16)22-24-12-21(19-11-26-29(2)14-19)23(27-22)31-15-20-7-4-8-30-20/h3,5-6,9-14,20H,4,7-8,15H2,1-2H3	NIPIREKHNAUZIB-UHFFFAOYSA-N	347912	US9790221, Compound 118	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347912&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357819	386049685							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687894	Cn1ccc(n1)-c1cnc(nc1NC1CCOC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H23N7O/c1-28-8-6-20(27-28)19-12-23-21(26-22(19)25-18-7-9-30-14-18)16-5-3-4-15(10-16)17-11-24-29(2)13-17/h3-6,8,10-13,18H,7,9,14H2,1-2H3,(H,23,25,26)	MRHACWXWDJTBGE-UHFFFAOYSA-N	347913	US9790221, Compound 119	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347913&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357820	386049686							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687896	Cn1ccc(n1)-c1cnc(nc1NC[C@H](O)CO)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C21H23N7O2/c1-27-7-6-19(26-27)18-11-23-20(25-21(18)22-10-17(30)13-29)15-5-3-4-14(8-15)16-9-24-28(2)12-16/h3-9,11-12,17,29-30H,10,13H2,1-2H3,(H,22,23,25)/t17-/m0/s1	ZXICHULZXNAPKS-KRWDZBQOSA-N	347914	US9790221, Compound 120	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347914&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357821	386049687							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687898	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCNC2)n1	InChI=1S/C22H24N8/c1-29-13-17(9-25-29)15-4-3-5-16(8-15)21-24-12-20(18-10-26-30(2)14-18)22(28-21)27-19-6-7-23-11-19/h3-5,8-10,12-14,19,23H,6-7,11H2,1-2H3,(H,24,27,28)/t19-/m0/s1	CKBWZUMWUOJBRS-IBGZPJMESA-N	347915	US9790221, Compound 121	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347915&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357827	386049688							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687900	Cn1ccc(n1)-c1cnc(nc1NCC1CCCC(O)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H29N7O/c1-31-10-9-23(30-31)22-15-27-24(29-25(22)26-13-17-5-3-8-21(33)11-17)19-7-4-6-18(12-19)20-14-28-32(2)16-20/h4,6-7,9-10,12,14-17,21,33H,3,5,8,11,13H2,1-2H3,(H,26,27,29)	WQCGBCNFUIVHCV-UHFFFAOYSA-N	347916	US9790221, Compound 122	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347916&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357824	386049689							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687902	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCC(O)C2)n1	InChI=1S/C25H29N7O/c1-31-15-20(12-28-31)18-6-4-7-19(10-18)24-27-14-23(21-13-29-32(2)16-21)25(30-24)26-11-17-5-3-8-22(33)9-17/h4,6-7,10,12-17,22,33H,3,5,8-9,11H2,1-2H3,(H,26,27,30)	MKBKKMSPJMRACX-UHFFFAOYSA-N	347917	US9790221, Compound 123	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347917&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357823	386049690							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687904	Cn1ccc(n1)-c1cnc(nc1N[C@@H]1C[C@H](N)C1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8/c1-29-7-6-20(28-29)19-12-24-21(27-22(19)26-18-9-17(23)10-18)15-5-3-4-14(8-15)16-11-25-30(2)13-16/h3-8,11-13,17-18H,9-10,23H2,1-2H3,(H,24,26,27)/t17-,18+	FPPAEZQMHMCZAB-HDICACEKSA-N	347918	US9790221, Compound 124	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347918&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357826	386049691							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687906	Cn1ccc(n1)-c1cnc(nc1NC1CCCCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8/c1-31-11-9-22(30-31)21-15-26-23(29-24(21)28-20-8-3-4-10-25-14-20)18-7-5-6-17(12-18)19-13-27-32(2)16-19/h5-7,9,11-13,15-16,20,25H,3-4,8,10,14H2,1-2H3,(H,26,28,29)	VJORIFWGPCUKQE-UHFFFAOYSA-N	347919	US9790221, Compound 125	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347919&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357825	386049692							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687908	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CCNC[C@H]2O)n1	InChI=1S/C24H28N8O/c1-31-14-19(10-28-31)16-4-3-5-17(8-16)23-27-12-21(20-11-29-32(2)15-20)24(30-23)26-9-18-6-7-25-13-22(18)33/h3-5,8,10-12,14-15,18,22,25,33H,6-7,9,13H2,1-2H3,(H,26,27,30)/t18-,22-/m1/s1	RCWDLUNSANAZGF-XMSQKQJNSA-N	347920	US9790221, Compound 126	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347920	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347920&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357829	386049693							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687910	Cc1nnc(s1)-c1cnc(nc1NCCN1CCS(=O)(=O)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8O2S2/c1-16-28-29-23(34-16)20-14-25-21(18-5-3-4-17(12-18)19-13-26-30(2)15-19)27-22(20)24-6-7-31-8-10-35(32,33)11-9-31/h3-5,12-15H,6-11H2,1-2H3,(H,24,25,27)	QCELRETUHNQFIM-UHFFFAOYSA-N	347921	US9790221, Compound 127	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347921&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357828	386049694							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687912	Cc1nnc(s1)-c1cnc(nc1NC1CCC(N)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8S/c1-14-29-30-23(32-14)20-12-25-21(28-22(20)27-19-8-6-18(24)7-9-19)16-5-3-4-15(10-16)17-11-26-31(2)13-17/h3-5,10-13,18-19H,6-9,24H2,1-2H3,(H,25,27,28)	QGRQFIXWJXBWPI-UHFFFAOYSA-N	347922	US9790221, Compound 128	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347922&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357830	386049695							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687914	Cc1nnc(s1)-c1cnc(nc1N[C@H]1CC[C@H](CC1)NS(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O2S2/c1-15-29-30-24(35-15)21-13-25-22(17-6-4-5-16(11-17)18-12-26-32(2)14-18)28-23(21)27-19-7-9-20(10-8-19)31-36(3,33)34/h4-6,11-14,19-20,31H,7-10H2,1-3H3,(H,25,27,28)/t19-,20+	UTIGOFYWZOYJCR-BGYRXZFFSA-N	347923	US9790221, Compound 129	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347923&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357961	386049696							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687916	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CNC[C@@H](F)C2)n1	InChI=1S/C23H25FN8/c1-31-13-17(8-27-31)15-4-3-5-16(6-15)22-26-12-21(18-9-28-32(2)14-18)23(30-22)29-20-7-19(24)10-25-11-20/h3-6,8-9,12-14,19-20,25H,7,10-11H2,1-2H3,(H,26,29,30)/t19-,20-/m0/s1	FDZPILGOIAJRAI-PMACEKPBSA-N	347924	US9790221, Compound 130	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347924	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347924&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357831	386049697							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687918	Cn1ccc(n1)-c1cnc(nc1N[C@@H]1CCC[C@@H](O)[C@H]1O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H27N7O2/c1-30-10-9-19(29-30)18-13-25-23(28-24(18)27-20-7-4-8-21(32)22(20)33)16-6-3-5-15(11-16)17-12-26-31(2)14-17/h3,5-6,9-14,20-22,32-33H,4,7-8H2,1-2H3,(H,25,27,28)/t20-,21-,22+/m1/s1	VTHZNBKOPFWHOL-VSKRKVRLSA-N	347925	US9790221, Compound 131	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347925&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357832	386049698							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687920	Cn1ccc(n1)-c1cnc(nc1O[C@@H]1CCC[C@@H](N)[C@@H]1O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H27N7O2/c1-30-10-9-20(29-30)18-13-26-23(28-24(18)33-21-8-4-7-19(25)22(21)32)16-6-3-5-15(11-16)17-12-27-31(2)14-17/h3,5-6,9-14,19,21-22,32H,4,7-8,25H2,1-2H3/t19-,21-,22+/m1/s1	TUQMDKJRSRLFMP-FCEUIQTBSA-N	347926	US9790221, Compound 132	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347926&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357833	386049699							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687922	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CCC[C@@H](O)[C@H]2O)n1	InChI=1S/C24H27N7O2/c1-30-13-17(10-26-30)15-5-3-6-16(9-15)23-25-12-19(18-11-27-31(2)14-18)24(29-23)28-20-7-4-8-21(32)22(20)33/h3,5-6,9-14,20-22,32-33H,4,7-8H2,1-2H3,(H,25,28,29)/t20-,21-,22+/m1/s1	UVHWQKYXRJARRI-VSKRKVRLSA-N	347927	US9790221, Compound 133	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347927&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347834	386049700							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687924	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(O[C@@H]2CCC[C@@H](N)[C@@H]2O)n1	InChI=1S/C24H27N7O2/c1-30-13-17(10-27-30)15-5-3-6-16(9-15)23-26-12-19(18-11-28-31(2)14-18)24(29-23)33-21-8-4-7-20(25)22(21)32/h3,5-6,9-14,20-22,32H,4,7-8,25H2,1-2H3/t20-,21-,22+/m1/s1	KVOIBFBXADXYTG-VSKRKVRLSA-N	347928	US9790221, Compound 134	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347928&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347824	386049701							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687926	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC(C)(C)O)n1	InChI=1S/C23H27N7O/c1-23(2,31)8-9-24-22-20(19-12-27-30(4)15-19)13-25-21(28-22)17-7-5-6-16(10-17)18-11-26-29(3)14-18/h5-7,10-15,31H,8-9H2,1-4H3,(H,24,25,28)	AEXMNSSSGGQEQL-UHFFFAOYSA-N	347929	US9790221, Compound 135	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347929&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357836	386049702							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687928	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCC(F)(F)CC2)n1	InChI=1S/C25H27F2N7/c1-33-15-20(12-30-33)18-4-3-5-19(10-18)23-29-14-22(21-13-31-34(2)16-21)24(32-23)28-11-17-6-8-25(26,27)9-7-17/h3-5,10,12-17H,6-9,11H2,1-2H3,(H,28,29,32)	AAVYPFWLIYEXPD-UHFFFAOYSA-N	347930	US9790221, Compound 136	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347930&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357834	386049703							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687930	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCOCC2)n1	InChI=1S/C23H25N7O/c1-29-14-18(11-25-29)16-4-3-5-17(10-16)22-24-13-21(19-12-26-30(2)15-19)23(28-22)27-20-6-8-31-9-7-20/h3-5,10-15,20H,6-9H2,1-2H3,(H,24,27,28)	WXDQRKZVJRQFCU-UHFFFAOYSA-N	347931	US9790221, Compound 137	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347931&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357835	386049704							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687932	Cn1ccc(n1)-c1cnc(nc1NC1CCOCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H25N7O/c1-29-9-6-21(28-29)20-14-24-22(27-23(20)26-19-7-10-31-11-8-19)17-5-3-4-16(12-17)18-13-25-30(2)15-18/h3-6,9,12-15,19H,7-8,10-11H2,1-2H3,(H,24,26,27)	AETWKAOLZXOERG-UHFFFAOYSA-N	347932	US9790221, Compound 138	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347932&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357837	386049705							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687934	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCC(C)(C)O)n1	InChI=1S/C24H29N7O/c1-24(2,32)9-6-10-25-23-21(20-13-28-31(4)16-20)14-26-22(29-23)18-8-5-7-17(11-18)19-12-27-30(3)15-19/h5,7-8,11-16,32H,6,9-10H2,1-4H3,(H,25,26,29)	FYPLNZXUWFDWFV-UHFFFAOYSA-N	347933	US9790221, Compound 139	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347933&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357838	386049706							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687936	Cn1ccc(n1)-c1cnc(nc1NCCCC(C)(C)O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H29N7O/c1-24(2,32)10-6-11-25-23-20(21-9-12-30(3)29-21)15-26-22(28-23)18-8-5-7-17(13-18)19-14-27-31(4)16-19/h5,7-9,12-16,32H,6,10-11H2,1-4H3,(H,25,26,28)	GCYKZGYYQMTSQA-UHFFFAOYSA-N	347934	US9790221, Compound 140	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347934&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357839	386049707							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687938	CN(CC1CC(F)(F)C1)c1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H25F2N7/c1-31(13-16-8-24(25,26)9-16)23-21(20-11-29-33(3)15-20)12-27-22(30-23)18-6-4-5-17(7-18)19-10-28-32(2)14-19/h4-7,10-12,14-16H,8-9,13H2,1-3H3	SYBALGURGFDLRV-UHFFFAOYSA-N	347935	US9790221, Compound 141	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347935&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357840	386049708							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687940	CN(CC1CC(F)(F)C1)c1nc(ncc1-c1ccn(C)n1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H25F2N7/c1-31(14-16-10-24(25,26)11-16)23-20(21-7-8-32(2)30-21)13-27-22(29-23)18-6-4-5-17(9-18)19-12-28-33(3)15-19/h4-9,12-13,15-16H,10-11,14H2,1-3H3	PEZAOZDZXLEDPV-UHFFFAOYSA-N	347936	US9790221, Compound 142	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347936&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357841	386049709							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687942	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](N)CC2)n1	InChI=1S/C24H28N8/c1-31-14-18(11-27-31)16-4-3-5-17(10-16)23-26-13-22(19-12-28-32(2)15-19)24(30-23)29-21-8-6-20(25)7-9-21/h3-5,10-15,20-21H,6-9,25H2,1-2H3,(H,26,29,30)/t20-,21-	HRKWQXXRXVOSOT-MEMLXQNLSA-N	347937	US9790221, Compound 143	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347937&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357752	386049710							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687944	Cn1ccc(n1)-c1cnc(nc1NCC1CCNC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8/c1-30-9-7-21(29-30)20-14-26-22(28-23(20)25-12-16-6-8-24-11-16)18-5-3-4-17(10-18)19-13-27-31(2)15-19/h3-5,7,9-10,13-16,24H,6,8,11-12H2,1-2H3,(H,25,26,28)	BORFUWYMIJRVOF-UHFFFAOYSA-N	347938	US9790221, Compound 144	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347938&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357842	386049711							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687946	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCNC2)n1	InChI=1S/C23H26N8/c1-30-14-19(11-27-30)17-4-3-5-18(8-17)22-26-13-21(20-12-28-31(2)15-20)23(29-22)25-10-16-6-7-24-9-16/h3-5,8,11-16,24H,6-7,9-10H2,1-2H3,(H,25,26,29)	FBDUIWWBUPBMON-UHFFFAOYSA-N	347939	US9790221, Compound 145	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347939&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357843	386049712							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687948	Cc1nnc(s1)-c1cnc(nc1NCCN1CCOCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8OS/c1-16-28-29-23(33-16)20-14-25-21(27-22(20)24-6-7-31-8-10-32-11-9-31)18-5-3-4-17(12-18)19-13-26-30(2)15-19/h3-5,12-15H,6-11H2,1-2H3,(H,24,25,27)	KXICWWUXDNOEEY-UHFFFAOYSA-N	347940	US9790221, Compound 146	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347940&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357844	386049713							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687950	Cn1ccc(n1)-c1cnc(nc1N[C@H]1CC[C@H](O)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H27N7O/c1-30-11-10-22(29-30)21-14-25-23(28-24(21)27-19-6-8-20(32)9-7-19)17-5-3-4-16(12-17)18-13-26-31(2)15-18/h3-5,10-15,19-20,32H,6-9H2,1-2H3,(H,25,27,28)/t19-,20-	MWUAVLGNHYIZIV-MXVIHJGJSA-N	347941	US9790221, Compound 147	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347941&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357845	386049714							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687952	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCNCC1	InChI=1S/C22H24N8/c1-28-14-18(11-25-28)16-4-3-5-17(10-16)21-24-13-20(19-12-26-29(2)15-19)22(27-21)30-8-6-23-7-9-30/h3-5,10-15,23H,6-9H2,1-2H3	BIDVJYQOMBSKMA-UHFFFAOYSA-N	347942	US9790221, Compound 148	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347942&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357846	386049715							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687954	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](O)CC2)n1	InChI=1S/C24H27N7O/c1-30-14-18(11-26-30)16-4-3-5-17(10-16)23-25-13-22(19-12-27-31(2)15-19)24(29-23)28-20-6-8-21(32)9-7-20/h3-5,10-15,20-21,32H,6-9H2,1-2H3,(H,25,28,29)/t20-,21-	ZBHHGSJIUFAWAM-MEMLXQNLSA-N	347943	US9790221, Compound 149	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347943&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357847	386049716							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687956	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC3CNCC23)n1	InChI=1S/C25H28N8/c1-32-14-19(10-28-32)16-4-3-5-17(8-16)24-27-13-22(20-11-29-33(2)15-20)25(31-24)30-23-7-6-18-9-26-12-21(18)23/h3-5,8,10-11,13-15,18,21,23,26H,6-7,9,12H2,1-2H3,(H,27,30,31)	FQVZKJHIGKCQPP-UHFFFAOYSA-N	347944	US9790221, Compound 150	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347944&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357848	386049717							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687958	Cc1nnc(s1)-c1cnc(nc1NC1CCN(CC1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H26N8O2S2/c1-15-28-29-23(34-15)20-13-24-21(17-6-4-5-16(11-17)18-12-25-30(2)14-18)27-22(20)26-19-7-9-31(10-8-19)35(3,32)33/h4-6,11-14,19H,7-10H2,1-3H3,(H,24,26,27)	KAEHEBCSGIXCIU-UHFFFAOYSA-N	347945	US9790221, Compound 151	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347945&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357849	386049718							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687960	Cn1ccc(n1)-c1cnc(nc1NC1C2CCCC1CC(N)C2)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C27H32N8/c1-34-10-9-24(33-34)23-15-29-26(20-8-3-5-17(11-20)21-14-30-35(2)16-21)32-27(23)31-25-18-6-4-7-19(25)13-22(28)12-18/h3,5,8-11,14-16,18-19,22,25H,4,6-7,12-13,28H2,1-2H3,(H,29,31,32)	RMCSHDIFRGAKAH-UHFFFAOYSA-N	347946	US9790221, Compound 152	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347946&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357850	386049719							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687962	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2C3CCCC2CC(N)C3)n1	InChI=1S/C27H32N8/c1-34-15-21(12-30-34)17-5-3-8-20(9-17)26-29-14-24(22-13-31-35(2)16-22)27(33-26)32-25-18-6-4-7-19(25)11-23(28)10-18/h3,5,8-9,12-16,18-19,23,25H,4,6-7,10-11,28H2,1-2H3,(H,29,32,33)	YIIMCDGBBYACGQ-UHFFFAOYSA-N	347947	US9790221, Compound 153	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347947&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357854	386049720							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687964	Cn1ccc(n1)-c1cnc(nc1NC1CCC2CNCC12)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8/c1-32-9-8-23(31-32)21-14-27-24(17-5-3-4-16(10-17)19-12-28-33(2)15-19)30-25(21)29-22-7-6-18-11-26-13-20(18)22/h3-5,8-10,12,14-15,18,20,22,26H,6-7,11,13H2,1-2H3,(H,27,29,30)	SACFRRGQTRJSCT-UHFFFAOYSA-N	347948	US9790221, Compound 154	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347948&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357853	386049721							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687966	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@@H]2CC[C@H](O)CC2)n1	InChI=1S/C25H29N7O/c1-31-15-20(12-28-31)18-4-3-5-19(10-18)24-27-14-23(21-13-29-32(2)16-21)25(30-24)26-11-17-6-8-22(33)9-7-17/h3-5,10,12-17,22,33H,6-9,11H2,1-2H3,(H,26,27,30)/t17-,22+	DFNACNVQYDSBPI-LMTLIKQPSA-N	347949	US9790221, Compound 155	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347949&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357851	386049722							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687968	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CC[C@H](O)CC2)n1	InChI=1S/C25H29N7O/c1-31-15-20(12-28-31)18-4-3-5-19(10-18)24-27-14-23(21-13-29-32(2)16-21)25(30-24)26-11-17-6-8-22(33)9-7-17/h3-5,10,12-17,22,33H,6-9,11H2,1-2H3,(H,26,27,30)/t17-,22-	DFNACNVQYDSBPI-VVOJOOEHSA-N	347950	US9790221, Compound 156	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347950	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347950&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357851	386049723							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687970	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CC2)n1	InChI=1S/C22H23N7/c1-28-13-18(10-25-28)16-4-3-5-17(8-16)21-24-12-20(19-11-26-29(2)14-19)22(27-21)23-9-15-6-7-15/h3-5,8,10-15H,6-7,9H2,1-2H3,(H,23,24,27)	CFMHYGMVNHEOJZ-UHFFFAOYSA-N	347951	US9790221, Compound 157	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347951	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347951&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357855	386049724							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687972	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCN(C2)S(C)(=O)=O)n1	InChI=1S/C24H28N8O2S/c1-30-15-20(11-27-30)18-5-4-6-19(9-18)23-26-13-22(21-12-28-31(2)16-21)24(29-23)25-10-17-7-8-32(14-17)35(3,33)34/h4-6,9,11-13,15-17H,7-8,10,14H2,1-3H3,(H,25,26,29)	ZWKRJPFIGSCCFS-UHFFFAOYSA-N	347952	US9790221, Compound 158	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347952&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357852	386049725							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687974	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2C3CCCC2CC(C3)NS(C)(=O)=O)n1	InChI=1S/C28H34N8O2S/c1-35-16-22(13-30-35)18-6-4-9-21(10-18)27-29-15-25(23-14-31-36(2)17-23)28(33-27)32-26-19-7-5-8-20(26)12-24(11-19)34-39(3,37)38/h4,6,9-10,13-17,19-20,24,26,34H,5,7-8,11-12H2,1-3H3,(H,29,32,33)	KZRLVYDBVTWWBA-UHFFFAOYSA-N	347953	US9790221, Compound 159	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347953&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357964	386049726							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687976	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3(C2)CC(C3)NS(C)(=O)=O)n1	InChI=1S/C26H30N8O2S/c1-33-15-19(12-28-33)17-5-4-6-18(7-17)24-27-14-23(20-13-29-34(2)16-20)25(31-24)30-21-8-26(9-21)10-22(11-26)32-37(3,35)36/h4-7,12-16,21-22,32H,8-11H2,1-3H3,(H,27,30,31)	KYBSKIVJKQTPHU-UHFFFAOYSA-N	347954	US9790221, Compound 160	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347954&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357965	386049727							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687978	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@@H](O)C2)n1	InChI=1S/C24H27N7O/c1-30-14-18(11-26-30)16-5-3-6-17(9-16)23-25-13-22(19-12-27-31(2)15-19)24(29-23)28-20-7-4-8-21(32)10-20/h3,5-6,9,11-15,20-21,32H,4,7-8,10H2,1-2H3,(H,25,28,29)/t20-,21+/m0/s1	MQRCXWAWMNUONA-LEWJYISDSA-N	347955	US9790221, Compound 161	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347955&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357856	386049728							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687980	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@H](O)C2)n1	InChI=1S/C24H27N7O/c1-30-14-18(11-26-30)16-5-3-6-17(9-16)23-25-13-22(19-12-27-31(2)15-19)24(29-23)28-20-7-4-8-21(32)10-20/h3,5-6,9,11-15,20-21,32H,4,7-8,10H2,1-2H3,(H,25,28,29)/t20-,21-/m0/s1	MQRCXWAWMNUONA-SFTDATJTSA-N	347956	US9790221, Compound 162	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347956&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357860	386049729							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687982	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCC2)n1	InChI=1S/C23H25N7/c1-29-14-19(11-26-29)17-7-4-8-18(9-17)22-25-13-21(20-12-27-30(2)15-20)23(28-22)24-10-16-5-3-6-16/h4,7-9,11-16H,3,5-6,10H2,1-2H3,(H,24,25,28)	VYMWIVHKLJFCMV-UHFFFAOYSA-N	347957	US9790221, Compound 163	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347957&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357857	386049730							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687984	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CC[C@@H](O)C2)n1	InChI=1S/C24H27N7O/c1-30-14-19(11-27-30)17-4-3-5-18(9-17)23-26-13-22(20-12-28-31(2)15-20)24(29-23)25-10-16-6-7-21(32)8-16/h3-5,9,11-16,21,32H,6-8,10H2,1-2H3,(H,25,26,29)/t16-,21+/m0/s1	ARZAFZSJLDFLAJ-HRAATJIYSA-N	347958	US9790221, Compound 164	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347958&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357862	386049731							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687986	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CC[C@H](O)C2)n1	InChI=1S/C24H27N7O/c1-30-14-19(11-27-30)17-4-3-5-18(9-17)23-26-13-22(20-12-28-31(2)15-20)24(29-23)25-10-16-6-7-21(32)8-16/h3-5,9,11-16,21,32H,6-8,10H2,1-2H3,(H,25,26,29)/t16-,21-/m0/s1	ARZAFZSJLDFLAJ-KKSFZXQISA-N	347959	US9790221, Compound 165	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347959&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357859	386049732							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687988	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCOC2)n1	InChI=1S/C23H25N7O/c1-29-13-19(10-26-29)17-4-3-5-18(8-17)22-25-12-21(20-11-27-30(2)14-20)23(28-22)24-9-16-6-7-31-15-16/h3-5,8,10-14,16H,6-7,9,15H2,1-2H3,(H,24,25,28)	OLXFEWAMNHOWMU-UHFFFAOYSA-N	347960	US9790221, Compound 166	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347960&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357861	386049733							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687990	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC(O)C2)n1	InChI=1S/C23H25N7O/c1-29-13-17(10-25-29)15-4-3-5-16(8-15)22-24-12-21(18-11-26-30(2)14-18)23(28-22)27-19-6-7-20(31)9-19/h3-5,8,10-14,19-20,31H,6-7,9H2,1-2H3,(H,24,27,28)	PAZMLZLHHPILSR-UHFFFAOYSA-N	347961	US9790221, Compound 167	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347961&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357863	386049734							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687992	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC3CN(CC23)S(C)(=O)=O)n1	InChI=1S/C26H30N8O2S/c1-32-13-20(10-28-32)17-5-4-6-18(9-17)25-27-12-22(21-11-29-33(2)14-21)26(31-25)30-24-8-7-19-15-34(16-23(19)24)37(3,35)36/h4-6,9-14,19,23-24H,7-8,15-16H2,1-3H3,(H,27,30,31)	KWIJLQOBOWRJPV-UHFFFAOYSA-N	347962	US9790221, Compound 168	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347962&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357864	386049735							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687994	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3(C2)CCN(C3)S(C)(=O)=O)n1	InChI=1S/C26H30N8O2S/c1-32-15-20(12-28-32)18-5-4-6-19(9-18)24-27-14-23(21-13-29-33(2)16-21)25(31-24)30-22-10-26(11-22)7-8-34(17-26)37(3,35)36/h4-6,9,12-16,22H,7-8,10-11,17H2,1-3H3,(H,27,30,31)	IPZCKIRKUDTKAH-UHFFFAOYSA-N	347963	US9790221, Compound 169	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347963&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357865	386049736							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687996	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCN(C2)S(C)(=O)=O)n1	InChI=1S/C23H26N8O2S/c1-29-13-18(10-25-29)16-5-4-6-17(9-16)22-24-12-21(19-11-26-30(2)14-19)23(28-22)27-20-7-8-31(15-20)34(3,32)33/h4-6,9-14,20H,7-8,15H2,1-3H3,(H,24,27,28)/t20-/m0/s1	FZDJXVAWYBYVTH-FQEVSTJZSA-N	347964	US9790221, Compound 170	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347964&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357866	386049737							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
687998	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CCN(C2)S(C)(=O)=O)n1	InChI=1S/C23H26N8O2S/c1-29-13-18(10-25-29)16-5-4-6-17(9-16)22-24-12-21(19-11-26-30(2)14-19)23(28-22)27-20-7-8-31(15-20)34(3,32)33/h4-6,9-14,20H,7-8,15H2,1-3H3,(H,24,27,28)/t20-/m1/s1	FZDJXVAWYBYVTH-HXUWFJFHSA-N	347965	US9790221, Compound 171	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347965&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357867	386049738							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688000	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CN(CCO2)S(C)(=O)=O)n1	InChI=1S/C24H28N8O3S/c1-30-14-19(10-27-30)17-5-4-6-18(9-17)23-26-13-22(20-11-28-31(2)15-20)24(29-23)25-12-21-16-32(7-8-35-21)36(3,33)34/h4-6,9-11,13-15,21H,7-8,12,16H2,1-3H3,(H,25,26,29)	QGUWKGBZVOGRGA-UHFFFAOYSA-N	347966	US9790221, Compound 172	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347966&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357868	386049739							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688002	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2[C@@H]3CN(C[C@H]23)S(C)(=O)=O)n1	InChI=1S/C25H28N8O2S/c1-31-12-18(8-28-31)16-5-4-6-17(7-16)24-26-10-20(19-9-29-32(2)13-19)25(30-24)27-11-21-22-14-33(15-23(21)22)36(3,34)35/h4-10,12-13,21-23H,11,14-15H2,1-3H3,(H,26,27,30)/t21?,22-,23+	AQQXBVGVZRVHBA-NOTZXAQLSA-N	347967	US9790221, Compound 173	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347967&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357869	386049740							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688004	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CCN(C2)S(C)(=O)=O)n1	InChI=1S/C24H28N8O2S/c1-30-15-20(11-27-30)18-5-4-6-19(9-18)23-26-13-22(21-12-28-31(2)16-21)24(29-23)25-10-17-7-8-32(14-17)35(3,33)34/h4-6,9,11-13,15-17H,7-8,10,14H2,1-3H3,(H,25,26,29)/t17-/m1/s1	ZWKRJPFIGSCCFS-QGZVFWFLSA-N	347968	US9790221, Compound 174	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347968&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357870	386049741							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688006	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC2CCN(C2)S(C)(=O)=O)n1	InChI=1S/C25H30N8O2S/c1-31-16-21(12-28-31)19-5-4-6-20(11-19)24-27-14-23(22-13-29-32(2)17-22)25(30-24)26-9-7-18-8-10-33(15-18)36(3,34)35/h4-6,11-14,16-18H,7-10,15H2,1-3H3,(H,26,27,30)	ZVVNQPGCNBMROC-UHFFFAOYSA-N	347969	US9790221, Compound 175	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347969&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357873	386049742							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688008	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CC[C@@H](C2)NS(C)(=O)=O)n1	InChI=1S/C24H28N8O2S/c1-31-14-18(11-26-31)16-5-4-6-17(9-16)23-25-13-22(19-12-27-32(2)15-19)24(29-23)28-20-7-8-21(10-20)30-35(3,33)34/h4-6,9,11-15,20-21,30H,7-8,10H2,1-3H3,(H,25,28,29)/t20-,21+/m1/s1	NDEMKIYZHBESJY-RTWAWAEBSA-N	347970	US9790221, Compound 176	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347970&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357871	386049743							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688010	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCCNS(C)(=O)=O)n1	InChI=1S/C23H28N8O2S/c1-30-15-19(12-26-30)17-7-6-8-18(11-17)22-25-14-21(20-13-27-31(2)16-20)23(29-22)24-9-4-5-10-28-34(3,32)33/h6-8,11-16,28H,4-5,9-10H2,1-3H3,(H,24,25,29)	ORTJDUOECINQJS-UHFFFAOYSA-N	347971	US9790221, Compound 177	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347971&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357967	386049744							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688012	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCCCN(C2)S(C)(=O)=O)n1	InChI=1S/C25H30N8O2S/c1-31-15-20(12-27-31)18-7-6-8-19(11-18)24-26-14-23(21-13-28-32(2)16-21)25(30-24)29-22-9-4-5-10-33(17-22)36(3,34)35/h6-8,11-16,22H,4-5,9-10,17H2,1-3H3,(H,26,29,30)	KDEVAODGQITDKB-UHFFFAOYSA-N	347972	US9790221, Compound 178	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347972&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357872	386049745							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688014	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCNS(C)(=O)=O)n1	InChI=1S/C22H26N8O2S/c1-29-14-18(11-25-29)16-6-4-7-17(10-16)21-24-13-20(19-12-26-30(2)15-19)22(28-21)23-8-5-9-27-33(3,31)32/h4,6-7,10-15,27H,5,8-9H2,1-3H3,(H,23,24,28)	CXCVVVVOGXOQOQ-UHFFFAOYSA-N	347973	US9790221, Compound 179	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347973&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357876	386049746							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688016	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC(CO)(CO)C2)n1	InChI=1S/C24H27N7O2/c1-30-12-18(9-26-30)16-4-3-5-17(6-16)22-25-11-21(19-10-27-31(2)13-19)23(29-22)28-20-7-24(8-20,14-32)15-33/h3-6,9-13,20,32-33H,7-8,14-15H2,1-2H3,(H,25,28,29)	TWFRHKNZDSAPOT-UHFFFAOYSA-N	347974	US9790221, Compound 180	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347974&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357874	386049747							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688018	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CC(O)C2)n1	InChI=1S/C23H25N7O/c1-29-13-18(10-26-29)16-4-3-5-17(8-16)22-25-12-21(19-11-27-30(2)14-19)23(28-22)24-9-15-6-20(31)7-15/h3-5,8,10-15,20,31H,6-7,9H2,1-2H3,(H,24,25,28)	DVCQNDLDUIPIPD-UHFFFAOYSA-N	347975	US9790221, Compound 181	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347975&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357875	386049748							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688020	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@@H](CC2)NS(C)(=O)=O)n1	InChI=1S/C25H30N8O2S/c1-32-15-19(12-27-32)17-5-4-6-18(11-17)24-26-14-23(20-13-28-33(2)16-20)25(30-24)29-21-7-9-22(10-8-21)31-36(3,34)35/h4-6,11-16,21-22,31H,7-10H2,1-3H3,(H,26,29,30)/t21-,22-	XSLLIHGJXBVYOG-HZCBDIJESA-N	347976	US9790221, Compound 182	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347976&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357968	386049749							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688022	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2C[C@H](C2)NS(C)(=O)=O)n1	InChI=1S/C23H26N8O2S/c1-30-13-17(10-25-30)15-5-4-6-16(7-15)22-24-12-21(18-11-26-31(2)14-18)23(28-22)27-19-8-20(9-19)29-34(3,32)33/h4-7,10-14,19-20,29H,8-9H2,1-3H3,(H,24,27,28)/t19-,20+	ICKUQFBSRYDPQK-BGYRXZFFSA-N	347977	US9790221, Compound 183	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347977	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347977&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357969	386049750							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688024	Cc1nnc(s1)-c1cnc(nc1NCCNS(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C20H22N8O2S2/c1-13-26-27-20(31-13)17-11-22-18(25-19(17)21-7-8-24-32(3,29)30)15-6-4-5-14(9-15)16-10-23-28(2)12-16/h4-6,9-12,24H,7-8H2,1-3H3,(H,21,22,25)	LVJGYLPHROZBJA-UHFFFAOYSA-N	347978	US9790221, Compound 184	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347978&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357970	386049751							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688026	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](N)C2)n1	InChI=1S/C23H26N8/c1-30-13-17(10-26-30)15-4-3-5-16(8-15)22-25-12-21(18-11-27-31(2)14-18)23(29-22)28-20-7-6-19(24)9-20/h3-5,8,10-14,19-20H,6-7,9,24H2,1-2H3,(H,25,28,29)/t19-,20-/m0/s1	UABWFXULANPTAV-PMACEKPBSA-N	347979	US9790221, Compound 185	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347979&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357878	386049752							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688028	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CCC(N)(CC2)CC3)n1	InChI=1S/C26H30N8/c1-33-16-20(13-29-33)18-4-3-5-19(12-18)23-28-15-22(21-14-30-34(2)17-21)24(31-23)32-26-9-6-25(27,7-10-26)8-11-26/h3-5,12-17H,6-11,27H2,1-2H3,(H,28,31,32)	UVZZNIBRWHBBIY-UHFFFAOYSA-N	347980	US9790221, Compound 186	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347980&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357877	386049753							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688030	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CCC(CC2)(CC3)NS(C)(=O)=O)n1	InChI=1S/C27H32N8O2S/c1-34-17-21(14-29-34)19-5-4-6-20(13-19)24-28-16-23(22-15-30-35(2)18-22)25(31-24)32-26-7-10-27(11-8-26,12-9-26)33-38(3,36)37/h4-6,13-18,33H,7-12H2,1-3H3,(H,28,31,32)	OIVGNVDFQYCJRB-UHFFFAOYSA-N	347981	US9790221, Compound 187	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347981&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357971	386049754							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688032	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC(CN)C2)n1	InChI=1S/C23H26N8/c1-30-13-18(10-26-30)16-4-3-5-17(8-16)22-25-12-21(19-11-27-31(2)14-19)23(29-22)28-20-6-15(7-20)9-24/h3-5,8,10-15,20H,6-7,9,24H2,1-2H3,(H,25,28,29)	WSVHWKHDOXCPHB-UHFFFAOYSA-N	347982	US9790221, Compound 188	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347982	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347982&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347852	386049755							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688034	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3CC2N(C3)S(C)(=O)=O)n1	InChI=1S/C25H28N8O2S/c1-31-14-19(10-27-31)17-5-4-6-18(9-17)24-26-12-21(20-11-28-32(2)15-20)25(30-24)29-22-7-16-8-23(22)33(13-16)36(3,34)35/h4-6,9-12,14-16,22-23H,7-8,13H2,1-3H3,(H,26,29,30)	LRCCRTWLBUDDTG-UHFFFAOYSA-N	347983	US9790221, Compound 189	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347983&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357879	386049756							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688036	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@@H](C2)NS(C)(=O)=O)n1	InChI=1S/C24H28N8O2S/c1-31-14-18(11-26-31)16-5-4-6-17(9-16)23-25-13-22(19-12-27-32(2)15-19)24(29-23)28-20-7-8-21(10-20)30-35(3,33)34/h4-6,9,11-15,20-21,30H,7-8,10H2,1-3H3,(H,25,28,29)/t20-,21-/m0/s1	NDEMKIYZHBESJY-SFTDATJTSA-N	347984	US9790221, Compound 190	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347984&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357881	386049757							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688038	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CC2CNCC2C1	InChI=1S/C24H26N8/c1-30-12-20(9-27-30)16-4-3-5-17(6-16)23-26-11-22(21-10-28-31(2)13-21)24(29-23)32-14-18-7-25-8-19(18)15-32/h3-6,9-13,18-19,25H,7-8,14-15H2,1-2H3	OKSADBZHMRDLQH-UHFFFAOYSA-N	347985	US9790221, Compound 191	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347985&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357880	386049758							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688040	Cc1nnc(s1)-c1cnc(nc1NCC1CN(C1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H24N8O2S2/c1-14-27-28-22(33-14)19-10-24-20(17-6-4-5-16(7-17)18-9-25-29(2)13-18)26-21(19)23-8-15-11-30(12-15)34(3,31)32/h4-7,9-10,13,15H,8,11-12H2,1-3H3,(H,23,24,26)	HSJGUJMLHMBFCN-UHFFFAOYSA-N	347986	US9790221, Compound 192	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347986	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347986&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357882	386049759							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688042	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3CCC2N3)n1	InChI=1S/C24H26N8/c1-31-13-17(10-26-31)15-4-3-5-16(8-15)23-25-12-20(18-11-27-32(2)14-18)24(30-23)29-22-9-19-6-7-21(22)28-19/h3-5,8,10-14,19,21-22,28H,6-7,9H2,1-2H3,(H,25,29,30)	KVYKIXYSWVIKMR-UHFFFAOYSA-N	347987	US9790221, Compound 193	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347987&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357972	386049760							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688044	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC(CN)CC2)n1	InChI=1S/C25H30N8/c1-32-15-20(12-28-32)18-4-3-5-19(10-18)24-27-14-23(21-13-29-33(2)16-21)25(31-24)30-22-8-6-17(11-26)7-9-22/h3-5,10,12-17,22H,6-9,11,26H2,1-2H3,(H,27,30,31)	YNFYDOJJZKWRID-UHFFFAOYSA-N	347988	US9790221, Compound 194	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347988	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347988&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357883	386049761							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688046	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2C[C@H](CNS(C)(=O)=O)C2)n1	InChI=1S/C24H28N8O2S/c1-31-14-19(11-26-31)17-5-4-6-18(9-17)23-25-13-22(20-12-27-32(2)15-20)24(30-23)29-21-7-16(8-21)10-28-35(3,33)34/h4-6,9,11-16,21,28H,7-8,10H2,1-3H3,(H,25,29,30)/t16-,21+	VZTDACMGWBXNRQ-NBEIKUQISA-N	347989	US9790221, Compound 195	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347989&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347790	386049762							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688048	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2C[C@H](CNS(C)(=O)=O)C2)n1	InChI=1S/C24H28N8O2S/c1-31-14-19(11-26-31)17-5-4-6-18(9-17)23-25-13-22(20-12-27-32(2)15-20)24(30-23)29-21-7-16(8-21)10-28-35(3,33)34/h4-6,9,11-16,21,28H,7-8,10H2,1-3H3,(H,25,29,30)/t16-,21-	VZTDACMGWBXNRQ-OQIWPSSASA-N	347990	US9790221, Compound 196	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347990&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347790	386049763							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688050	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2C[C@H](N)C2)n1	InChI=1S/C22H24N8/c1-29-12-16(9-25-29)14-4-3-5-15(6-14)21-24-11-20(17-10-26-30(2)13-17)22(28-21)27-19-7-18(23)8-19/h3-6,9-13,18-19H,7-8,23H2,1-2H3,(H,24,27,28)/t18-,19-	NRQLGEWVVODBQU-WGSAOQKQSA-N	347991	US9790221, Compound 197	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347991&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357766	386049764							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688052	CC(=O)NCC1CCC(CC1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C27H32N8O/c1-18(36)28-12-19-7-9-24(10-8-19)32-27-25(23-14-31-35(3)17-23)15-29-26(33-27)21-6-4-5-20(11-21)22-13-30-34(2)16-22/h4-6,11,13-17,19,24H,7-10,12H2,1-3H3,(H,28,36)(H,29,32,33)	NPWIFLLNABNSHT-UHFFFAOYSA-N	347992	US9790221, Compound 198	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347992&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357884	386049765							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688054	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CC3CCC2N3S(C)(=O)=O)n1	InChI=1S/C25H28N8O2S/c1-31-14-18(11-27-31)16-5-4-6-17(9-16)24-26-13-21(19-12-28-32(2)15-19)25(30-24)29-22-10-20-7-8-23(22)33(20)36(3,34)35/h4-6,9,11-15,20,22-23H,7-8,10H2,1-3H3,(H,26,29,30)	QMQUBLYFSIGGEW-UHFFFAOYSA-N	347993	US9790221, Compound 199	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347993&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357885	386049766							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688056	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCC2N)n1	InChI=1S/C24H28N8/c1-31-14-19(11-28-31)16-5-3-6-17(9-16)23-27-13-21(20-12-29-32(2)15-20)24(30-23)26-10-18-7-4-8-22(18)25/h3,5-6,9,11-15,18,22H,4,7-8,10,25H2,1-2H3,(H,26,27,30)	VVIVYJDDTWZBAC-UHFFFAOYSA-N	347994	US9790221, Compound 200	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347994&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347814	386049767							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688058	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCC(CNS(C)(=O)=O)CC2)n1	InChI=1S/C26H32N8O2S/c1-33-16-21(13-28-33)19-5-4-6-20(11-19)25-27-15-24(22-14-29-34(2)17-22)26(32-25)31-23-9-7-18(8-10-23)12-30-37(3,35)36/h4-6,11,13-18,23,30H,7-10,12H2,1-3H3,(H,27,31,32)	PHTLITQNUCULAW-UHFFFAOYSA-N	347995	US9790221, Compound 201	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347995&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357886	386049768							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688060	CC(=O)N[C@H]1C[C@@H](C1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O/c1-15(33)28-20-8-21(9-20)29-24-22(19-11-27-32(3)14-19)12-25-23(30-24)17-6-4-5-16(7-17)18-10-26-31(2)13-18/h4-7,10-14,20-21H,8-9H2,1-3H3,(H,28,33)(H,25,29,30)/t20-,21-	OEFNVXHEWMKHEF-MEMLXQNLSA-N	347996	US9790221, Compound 202	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347996&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360929	386049769							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688062	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCC2NS(C)(=O)=O)n1	InChI=1S/C25H30N8O2S/c1-32-15-20(12-28-32)17-6-4-7-18(10-17)24-27-14-22(21-13-29-33(2)16-21)25(30-24)26-11-19-8-5-9-23(19)31-36(3,34)35/h4,6-7,10,12-16,19,23,31H,5,8-9,11H2,1-3H3,(H,26,27,30)	GJURUAGJTOURAF-UHFFFAOYSA-N	347997	US9790221, Compound 203	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347997&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357887	386049770							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688066	CC(=O)NC1CCC(CC1)Nc1nc(ncc1-c1nnc(C)s1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8OS/c1-15(34)28-20-7-9-21(10-8-20)29-24-22(25-32-31-16(2)35-25)13-26-23(30-24)18-6-4-5-17(11-18)19-12-27-33(3)14-19/h4-6,11-14,20-21H,7-10H2,1-3H3,(H,28,34)(H,26,29,30)	YCDWHIJZUUZCMW-UHFFFAOYSA-N	347998	US9790221, Compound 205	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347998&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360797	386049771							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688068	CC(=O)N[C@@H]1CCC[C@@H]1CNc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C26H30N8O/c1-17(35)31-24-9-5-8-20(24)11-27-26-23(22-13-30-34(3)16-22)14-28-25(32-26)19-7-4-6-18(10-19)21-12-29-33(2)15-21/h4,6-7,10,12-16,20,24H,5,8-9,11H2,1-3H3,(H,31,35)(H,27,28,32)/t20-,24-/m1/s1	ICZBPTMYVZVEQB-HYBUGGRVSA-N	347999	US9790221, Compound 206	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=347999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=347999&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347826	386049772							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688070	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@H](O)[C@@H]2O)n1	InChI=1S/C24H27N7O2/c1-30-13-17(10-26-30)15-5-3-6-16(9-15)23-25-12-19(18-11-27-31(2)14-18)24(29-23)28-20-7-4-8-21(32)22(20)33/h3,5-6,9-14,20-22,32-33H,4,7-8H2,1-2H3,(H,25,28,29)/t20-,21-,22+/m0/s1	UVHWQKYXRJARRI-FDFHNCONSA-N	348000	US9790221, Compound 208	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348000&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347844	386049773							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688072	Cc1nnc(s1)-c1cnc(nc1NC1CCC(CC1)NS(=O)(=O)C1CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C26H30N8O2S2/c1-16-31-32-26(37-16)23-14-27-24(18-5-3-4-17(12-18)19-13-28-34(2)15-19)30-25(23)29-20-6-8-21(9-7-20)33-38(35,36)22-10-11-22/h3-5,12-15,20-22,33H,6-11H2,1-2H3,(H,27,29,30)	SNXVABRGTXWOBN-UHFFFAOYSA-N	348001	US9790221, Compound 209	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348001&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360860	386049774							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688074	CC(C)Nc1nc(ncc1-c1nnc(s1)C1CCNCC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8S/c1-15(2)28-22-20(24-31-30-23(33-24)16-7-9-25-10-8-16)13-26-21(29-22)18-6-4-5-17(11-18)19-12-27-32(3)14-19/h4-6,11-16,25H,7-10H2,1-3H3,(H,26,28,29)	PSLJDZUBNJDMJP-UHFFFAOYSA-N	348002	US9790221, Compound 210	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348002&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357888	386049775							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688076	CC(=O)NC[C@H]1C[C@H](C1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8O/c1-16(34)26-10-17-7-22(8-17)30-25-23(21-12-29-33(3)15-21)13-27-24(31-25)19-6-4-5-18(9-19)20-11-28-32(2)14-20/h4-6,9,11-15,17,22H,7-8,10H2,1-3H3,(H,26,34)(H,27,30,31)/t17-,22+	ZOPDRRJPLQTJDQ-LMTLIKQPSA-N	348003	US9790221, Compound 211	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348003&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347810	386049776							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688078	CC(=O)NC[C@H]1C[C@@H](C1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8O/c1-16(34)26-10-17-7-22(8-17)30-25-23(21-12-29-33(3)15-21)13-27-24(31-25)19-6-4-5-18(9-19)20-11-28-32(2)14-20/h4-6,9,11-15,17,22H,7-8,10H2,1-3H3,(H,26,34)(H,27,30,31)/t17-,22-	ZOPDRRJPLQTJDQ-VVOJOOEHSA-N	348004	US9790221, Compound 212	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348004&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347810	386049777							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688080	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCS(C)(=O)=O)n1	InChI=1S/C22H25N7O2S/c1-28-14-18(11-25-28)16-6-4-7-17(10-16)21-24-13-20(19-12-26-29(2)15-19)22(27-21)23-8-5-9-32(3,30)31/h4,6-7,10-15H,5,8-9H2,1-3H3,(H,23,24,27)	GRXHYNHDCWOCIT-UHFFFAOYSA-N	348005	US9790221, Compound 213	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348005&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357889	386049778							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688082	Cc1nnc(s1)-c1cnc(nc1NC1CCC(F)(F)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C23H23F2N7S/c1-14-30-31-22(33-14)19-12-26-20(29-21(19)28-18-6-8-23(24,25)9-7-18)16-5-3-4-15(10-16)17-11-27-32(2)13-17/h3-5,10-13,18H,6-9H2,1-2H3,(H,26,28,29)	XWSYCQVZTJNFLP-UHFFFAOYSA-N	348006	US9790221, Compound 214	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348006&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357892	386049779							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688084	Cc1ccc(cn1)-c1cnc(nc1NC1CCN(CC1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C26H29N7O2S/c1-18-7-8-21(14-27-18)24-16-28-25(20-6-4-5-19(13-20)22-15-29-32(2)17-22)31-26(24)30-23-9-11-33(12-10-23)36(3,34)35/h4-8,13-17,23H,9-12H2,1-3H3,(H,28,30,31)	MALVNUQJMAUFPP-UHFFFAOYSA-N	348007	US9790221, Compound 215	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348007&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357890	386049780							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688086	Cc1nnc(s1)-c1cnc(nc1NCC(O)C(F)(F)F)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C20H18F3N7OS/c1-11-28-29-19(32-11)15-8-24-17(27-18(15)25-9-16(31)20(21,22)23)13-5-3-4-12(6-13)14-7-26-30(2)10-14/h3-8,10,16,31H,9H2,1-2H3,(H,24,25,27)	JEZMXSIDNJXCNH-UHFFFAOYSA-N	348008	US9790221, Compound 216	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348008&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357896	386049781							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688088	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCCOC2)n1	InChI=1S/C24H27N7O/c1-30-14-20(11-27-30)18-6-3-7-19(9-18)23-26-13-22(21-12-28-31(2)15-21)24(29-23)25-10-17-5-4-8-32-16-17/h3,6-7,9,11-15,17H,4-5,8,10,16H2,1-2H3,(H,25,26,29)	JUEYPYROHVUFAL-UHFFFAOYSA-N	348009	US9790221, Compound 217	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348009&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357897	386049782							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688090	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(O)C1	InChI=1S/C22H23N7O/c1-27-12-17(9-24-27)15-4-3-5-16(8-15)21-23-11-20(18-10-25-28(2)13-18)22(26-21)29-7-6-19(30)14-29/h3-5,8-13,19,30H,6-7,14H2,1-2H3	APTFQCJBSOWLMK-UHFFFAOYSA-N	348010	US9790221, Compound 218	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348010&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357891	386049783							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688092	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(O)CC1	InChI=1S/C23H25N7O/c1-28-14-18(11-25-28)16-4-3-5-17(10-16)22-24-13-21(19-12-26-29(2)15-19)23(27-22)30-8-6-20(31)7-9-30/h3-5,10-15,20,31H,6-9H2,1-2H3	YWZQSFLJSQHSAX-UHFFFAOYSA-N	348011	US9790221, Compound 219	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348011&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357899	386049784							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688094	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCCC(CO)C1	InChI=1S/C24H27N7O/c1-29-14-20(10-26-29)18-6-3-7-19(9-18)23-25-12-22(21-11-27-30(2)15-21)24(28-23)31-8-4-5-17(13-31)16-32/h3,6-7,9-12,14-15,17,32H,4-5,8,13,16H2,1-2H3	QOSBOEZPLRNXCX-UHFFFAOYSA-N	348012	US9790221, Compound 220	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348012&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357893	386049785							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688096	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CC[C@H](O)CC2)n1	InChI=1S/C24H27N7O/c1-30-14-18(11-26-30)16-4-3-5-17(10-16)23-25-13-22(19-12-27-31(2)15-19)24(29-23)28-20-6-8-21(32)9-7-20/h3-5,10-15,20-21,32H,6-9H2,1-2H3,(H,25,28,29)/t20-,21+	ZBHHGSJIUFAWAM-OYRHEFFESA-N	348013	US9790221, Compound 221	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348013&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357847	386049786							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688098	CN(CCC#N)c1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H22N8/c1-28(9-5-8-23)22-20(19-12-26-30(3)15-19)13-24-21(27-22)17-7-4-6-16(10-17)18-11-25-29(2)14-18/h4,6-7,10-15H,5,9H2,1-3H3	IOAFUECVQSRNGN-UHFFFAOYSA-N	348014	US9790221, Compound 222	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348014&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357894	386049787							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688100	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC(C)(C)C)n1	InChI=1S/C22H25N7/c1-22(2,3)27-21-19(18-11-25-29(5)14-18)12-23-20(26-21)16-8-6-7-15(9-16)17-10-24-28(4)13-17/h6-14H,1-5H3,(H,23,26,27)	ZZVVPSKFZYCFFP-UHFFFAOYSA-N	348015	US9790221, Compound 223	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348015&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357895	386049788							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688102	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@@H]2CCCC[C@H]2O)n1	InChI=1S/C25H29N7O/c1-31-15-20(12-28-31)17-7-5-8-18(10-17)24-27-14-22(21-13-29-32(2)16-21)25(30-24)26-11-19-6-3-4-9-23(19)33/h5,7-8,10,12-16,19,23,33H,3-4,6,9,11H2,1-2H3,(H,26,27,30)/t19-,23+/m0/s1	VISZBUCCUXLPMM-WMZHIEFXSA-N	348016	US9790221, Compound 224	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348016&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357898	386049789							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688104	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC[C@H]2CCCC[C@H]2O)n1	InChI=1S/C25H29N7O/c1-31-15-20(12-28-31)17-7-5-8-18(10-17)24-27-14-22(21-13-29-32(2)16-21)25(30-24)26-11-19-6-3-4-9-23(19)33/h5,7-8,10,12-16,19,23,33H,3-4,6,9,11H2,1-2H3,(H,26,27,30)/t19-,23-/m1/s1	VISZBUCCUXLPMM-AUSIDOKSSA-N	348017	US9790221, Compound 225	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348017&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357905	386049790							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688106	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CC(O)C1	InChI=1S/C21H21N7O/c1-26-10-16(7-23-26)14-4-3-5-15(6-14)20-22-9-19(17-8-24-27(2)11-17)21(25-20)28-12-18(29)13-28/h3-11,18,29H,12-13H2,1-2H3	SNERGDLBGMRKTO-UHFFFAOYSA-N	348018	US9790221, Compound 226	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348018&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357900	386049791							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688108	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC2(O)CCCC2)n1	InChI=1S/C25H29N7O/c1-31-16-20(13-28-31)18-6-5-7-19(12-18)23-27-15-22(21-14-29-32(2)17-21)24(30-23)26-11-10-25(33)8-3-4-9-25/h5-7,12-17,33H,3-4,8-11H2,1-2H3,(H,26,27,30)	GRGILPUCJDNRMP-UHFFFAOYSA-N	348019	US9790221, Compound 227	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348019&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357901	386049792							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688110	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(CCO)C1	InChI=1S/C24H27N7O/c1-29-15-20(11-26-29)18-4-3-5-19(10-18)23-25-13-22(21-12-27-30(2)16-21)24(28-23)31-8-6-17(14-31)7-9-32/h3-5,10-13,15-17,32H,6-9,14H2,1-2H3	JNZQNNYFTQATBT-UHFFFAOYSA-N	348020	US9790221, Compound 228	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348020&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357906	386049793							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688112	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCNCC2F)n1	InChI=1S/C24H27FN8/c1-32-14-19(10-29-32)16-4-3-5-17(8-16)23-28-12-21(20-11-30-33(2)15-20)24(31-23)27-9-18-6-7-26-13-22(18)25/h3-5,8,10-12,14-15,18,22,26H,6-7,9,13H2,1-2H3,(H,27,28,31)	YZLGYMQTFLBEJX-UHFFFAOYSA-N	348021	US9790221, Compound 229	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348021&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357909	386049794							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688114	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC[C@H]1CO	InChI=1S/C23H25N7O/c1-28-13-18(10-25-28)16-5-3-6-17(9-16)22-24-12-21(19-11-26-29(2)14-19)23(27-22)30-8-4-7-20(30)15-31/h3,5-6,9-14,20,31H,4,7-8,15H2,1-2H3/t20-/m0/s1	ZWUJSLCIUAQUIC-FQEVSTJZSA-N	348022	US9790221, Compound 230	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348022	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348022&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357911	386049795							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688116	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(F)CCNCC2)n1	InChI=1S/C24H27FN8/c1-32-14-19(11-29-32)17-4-3-5-18(10-17)22-27-13-21(20-12-30-33(2)15-20)23(31-22)28-16-24(25)6-8-26-9-7-24/h3-5,10-15,26H,6-9,16H2,1-2H3,(H,27,28,31)	UOHHRJSLBVIKCB-UHFFFAOYSA-N	348023	US9790221, Compound 231	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348023	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348023&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357913	386049796							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688118	COC(=O)[C@@H]1CCC[C@@H](C1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C26H29N7O2/c1-32-15-20(12-28-32)17-6-4-7-18(10-17)24-27-14-23(21-13-29-33(2)16-21)25(31-24)30-22-9-5-8-19(11-22)26(34)35-3/h4,6-7,10,12-16,19,22H,5,8-9,11H2,1-3H3,(H,27,30,31)/t19-,22+/m1/s1	CKZHNZHPDCAILF-KNQAVFIVSA-N	348024	US9790221, Compound 232	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348024&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357903	386049797							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688120	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@@H](CC2)N2CCOCC2)n1	InChI=1S/C28H34N8O/c1-34-18-22(15-30-34)20-4-3-5-21(14-20)27-29-17-26(23-16-31-35(2)19-23)28(33-27)32-24-6-8-25(9-7-24)36-10-12-37-13-11-36/h3-5,14-19,24-25H,6-13H2,1-2H3,(H,29,32,33)/t24-,25-	OTOZQHGGWWIOOP-SOAUALDESA-N	348025	US9790221, Compound 233	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348025&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357902	386049798							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688122	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2CCN(CC2F)S(C)(=O)=O)n1	InChI=1S/C25H29FN8O2S/c1-32-14-20(11-29-32)17-5-4-6-18(9-17)24-28-13-22(21-12-30-33(2)15-21)25(31-24)27-10-19-7-8-34(16-23(19)26)37(3,35)36/h4-6,9,11-15,19,23H,7-8,10,16H2,1-3H3,(H,27,28,31)	BLZVQAUSHZYNBO-UHFFFAOYSA-N	348026	US9790221, Compound 234	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348026&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357904	386049799							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688124	CC(=O)N1CCC(CNc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)C(F)C1	InChI=1S/C26H29FN8O/c1-17(36)35-8-7-20(24(27)16-35)10-28-26-23(22-12-31-34(3)15-22)13-29-25(32-26)19-6-4-5-18(9-19)21-11-30-33(2)14-21/h4-6,9,11-15,20,24H,7-8,10,16H2,1-3H3,(H,28,29,32)	POJYIORXZRBPCH-UHFFFAOYSA-N	348027	US9790221, Compound 235	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348027&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357908	386049800							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688126	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(F)CCN(CC2)S(C)(=O)=O)n1	InChI=1S/C25H29FN8O2S/c1-32-15-20(12-29-32)18-5-4-6-19(11-18)23-27-14-22(21-13-30-33(2)16-21)24(31-23)28-17-25(26)7-9-34(10-8-25)37(3,35)36/h4-6,11-16H,7-10,17H2,1-3H3,(H,27,28,31)	ZLXAHZNUDMVSQS-UHFFFAOYSA-N	348028	US9790221, Compound 236	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348028&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357907	386049801							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688128	CC(=O)N1CCC(F)(CNc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)CC1	InChI=1S/C26H29FN8O/c1-18(36)35-9-7-26(27,8-10-35)17-29-25-23(22-13-31-34(3)16-22)14-28-24(32-25)20-6-4-5-19(11-20)21-12-30-33(2)15-21/h4-6,11-16H,7-10,17H2,1-3H3,(H,28,29,32)	QLRRPGMVGUERAZ-UHFFFAOYSA-N	348029	US9790221, Compound 237	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348029&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357910	386049802							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688130	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCCC2O)n1	InChI=1S/C23H25N7O/c1-29-13-17(10-25-29)15-5-3-6-16(9-15)22-24-12-19(18-11-26-30(2)14-18)23(28-22)27-20-7-4-8-21(20)31/h3,5-6,9-14,20-21,31H,4,7-8H2,1-2H3,(H,24,27,28)	UZXZVYGDNUGMGM-UHFFFAOYSA-N	348030	US9790221, Compound 238	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348030&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357912	386049803							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688132	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(N)CC1	InChI=1S/C23H26N8/c1-29-14-18(11-26-29)16-4-3-5-17(10-16)22-25-13-21(19-12-27-30(2)15-19)23(28-22)31-8-6-20(24)7-9-31/h3-5,10-15,20H,6-9,24H2,1-2H3	YLQBHUZSTBTNCJ-UHFFFAOYSA-N	348031	US9790221, Compound 239	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348031&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357915	386049804							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688134	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(O)CCNCC2)n1	InChI=1S/C24H28N8O/c1-31-14-19(11-28-31)17-4-3-5-18(10-17)22-26-13-21(20-12-29-32(2)15-20)23(30-22)27-16-24(33)6-8-25-9-7-24/h3-5,10-15,25,33H,6-9,16H2,1-2H3,(H,26,27,30)	FGOSQWSPUHKOGY-UHFFFAOYSA-N	348032	US9790221, Compound 240	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348032&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357914	386049805							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688136	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CC[C@@H](N)C1	InChI=1S/C22H24N8/c1-28-12-17(9-25-28)15-4-3-5-16(8-15)21-24-11-20(18-10-26-29(2)13-18)22(27-21)30-7-6-19(23)14-30/h3-5,8-13,19H,6-7,14,23H2,1-2H3/t19-/m1/s1	FFIWHOSSFMYQPY-LJQANCHMSA-N	348033	US9790221, Compound 241	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348033&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357916	386049806							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688138	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CC(CN)(C2)C3)n1	InChI=1S/C24H26N8/c1-31-10-18(7-27-31)16-4-3-5-17(6-16)21-26-9-20(19-8-28-32(2)11-19)22(29-21)30-24-12-23(13-24,14-24)15-25/h3-11H,12-15,25H2,1-2H3,(H,26,29,30)	GEEUDQDQXKBOQF-UHFFFAOYSA-N	348034	US9790221, Compound 242	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348034&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357917	386049807							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688140	Cc1nnc(s1)-c1cnc(nc1NC1CCS(=O)(=O)CC1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C22H23N7O2S2/c1-14-27-28-22(32-14)19-12-23-20(26-21(19)25-18-6-8-33(30,31)9-7-18)16-5-3-4-15(10-16)17-11-24-29(2)13-17/h3-5,10-13,18H,6-9H2,1-2H3,(H,23,25,26)	NIBKKECXOUQTSV-UHFFFAOYSA-N	348035	US9790221, Compound 243	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348035&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357918	386049808							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688142	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCCCC2O)n1	InChI=1S/C24H27N7O/c1-30-14-18(11-26-30)16-6-5-7-17(10-16)23-25-13-20(19-12-27-31(2)15-19)24(29-23)28-21-8-3-4-9-22(21)32/h5-7,10-15,21-22,32H,3-4,8-9H2,1-2H3,(H,25,28,29)	LMHWBRUNYNTTJK-UHFFFAOYSA-N	348036	US9790221, Compound 244	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348036&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357919	386049809							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688144	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CC(CNS(C)(=O)=O)(C2)C3)n1	InChI=1S/C25H28N8O2S/c1-32-11-19(8-27-32)17-5-4-6-18(7-17)22-26-10-21(20-9-28-33(2)12-20)23(30-22)31-25-13-24(14-25,15-25)16-29-36(3,34)35/h4-12,29H,13-16H2,1-3H3,(H,26,30,31)	ZGPRKEMWOWGUPV-UHFFFAOYSA-N	348037	US9790221, Compound 245	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348037&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357920	386049810							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688146	CC(=O)N[C@@H]1CCN(C1)c1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H26N8O/c1-16(33)28-21-7-8-32(15-21)24-22(20-11-27-31(3)14-20)12-25-23(29-24)18-6-4-5-17(9-18)19-10-26-30(2)13-19/h4-6,9-14,21H,7-8,15H2,1-3H3,(H,28,33)/t21-/m1/s1	ZGNSMUYWBZRPGX-OAQYLSRUSA-N	348038	US9790221, Compound 246	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348038&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357921	386049811							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688148	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CC[C@H](C1)NS(C)(=O)=O	InChI=1S/C23H26N8O2S/c1-29-13-18(10-25-29)16-5-4-6-17(9-16)22-24-12-21(19-11-26-30(2)14-19)23(27-22)31-8-7-20(15-31)28-34(3,32)33/h4-6,9-14,20,28H,7-8,15H2,1-3H3/t20-/m1/s1	DPQLGRWMRSSMDH-HXUWFJFHSA-N	348039	US9790221, Compound 247	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348039&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357922	386049812							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688150	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCCC[C@H](O)[C@@H]2O)n1	InChI=1S/C25H29N7O2/c1-31-14-18(11-27-31)16-6-5-7-17(10-16)24-26-13-20(19-12-28-32(2)15-19)25(30-24)29-21-8-3-4-9-22(33)23(21)34/h5-7,10-15,21-23,33-34H,3-4,8-9H2,1-2H3,(H,26,29,30)/t21-,22-,23+/m0/s1	JGAOGPNHVTXBLP-RJGXRXQPSA-N	348040	US9790221, Compound 248	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348040&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357923	386049813							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688152	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(O)CCN(CC2)S(C)(=O)=O)n1	InChI=1S/C25H30N8O3S/c1-31-15-20(12-28-31)18-5-4-6-19(11-18)23-26-14-22(21-13-29-32(2)16-21)24(30-23)27-17-25(34)7-9-33(10-8-25)37(3,35)36/h4-6,11-16,34H,7-10,17H2,1-3H3,(H,26,27,30)	XPMUXAWUDPOKIW-UHFFFAOYSA-N	348041	US9790221, Compound 249	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348041&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357924	386049814							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688154	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(CC1)NS(C)(=O)=O	InChI=1S/C24H28N8O2S/c1-30-15-19(12-26-30)17-5-4-6-18(11-17)23-25-14-22(20-13-27-31(2)16-20)24(28-23)32-9-7-21(8-10-32)29-35(3,33)34/h4-6,11-16,21,29H,7-10H2,1-3H3	FASBDCBWCGKVME-UHFFFAOYSA-N	348042	US9790221, Compound 250	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348042&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357928	386049815							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688156	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC2CCCCN2)n1	InChI=1S/C25H30N8/c1-32-16-20(13-29-32)18-6-5-7-19(12-18)24-28-15-23(21-14-30-33(2)17-21)25(31-24)27-11-9-22-8-3-4-10-26-22/h5-7,12-17,22,26H,3-4,8-11H2,1-2H3,(H,27,28,31)	AFHQIYVPFBNONV-UHFFFAOYSA-N	348043	US9790221, Compound 251	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348043&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357925	386049816							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688158	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(N)CCCCC2)n1	InChI=1S/C25H30N8/c1-32-15-20(12-29-32)18-7-6-8-19(11-18)23-27-14-22(21-13-30-33(2)16-21)24(31-23)28-17-25(26)9-4-3-5-10-25/h6-8,11-16H,3-5,9-10,17,26H2,1-2H3,(H,27,28,31)	NCBVSQWLPZNMKD-UHFFFAOYSA-N	348044	US9790221, Compound 252	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348044&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357926	386049817							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688160	Cc1nnc(s1)-c1cnc(nc1NC1CCCN(CC1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O2S2/c1-16-29-30-24(35-16)21-14-25-22(18-7-4-6-17(12-18)19-13-26-31(2)15-19)28-23(21)27-20-8-5-10-32(11-9-20)36(3,33)34/h4,6-7,12-15,20H,5,8-11H2,1-3H3,(H,25,27,28)	VIOGMLCMHMBTBR-UHFFFAOYSA-N	348045	US9790221, Compound 253	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348045&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357927	386049818							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688162	Cc1nnc(s1)-c1cnc(nc1N[C@H]1CC[C@@H](CC1)NS(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C24H28N8O2S2/c1-15-29-30-24(35-15)21-13-25-22(17-6-4-5-16(11-17)18-12-26-32(2)14-18)28-23(21)27-19-7-9-20(10-8-19)31-36(3,33)34/h4-6,11-14,19-20,31H,7-10H2,1-3H3,(H,25,27,28)/t19-,20-	UTIGOFYWZOYJCR-MXVIHJGJSA-N	348046	US9790221, Compound 254	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348046&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357961	386049819							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688164	CC(=O)N1CCC(CC1)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H28N8O/c1-17(34)33-9-7-22(8-10-33)29-25-23(21-13-28-32(3)16-21)14-26-24(30-25)19-6-4-5-18(11-19)20-12-27-31(2)15-20/h4-6,11-16,22H,7-10H2,1-3H3,(H,26,29,30)	HCVYZVCMHVIECU-UHFFFAOYSA-N	348047	US9790221, Compound 255	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348047&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357929	386049820							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688166	CC(=O)NC1(CNc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)CCCCC1	InChI=1S/C27H32N8O/c1-19(36)33-27(10-5-4-6-11-27)18-29-26-24(23-14-31-35(3)17-23)15-28-25(32-26)21-9-7-8-20(12-21)22-13-30-34(2)16-22/h7-9,12-17H,4-6,10-11,18H2,1-3H3,(H,33,36)(H,28,29,32)	ZLPOAOZQVOSPDE-UHFFFAOYSA-N	348048	US9790221, Compound 256	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348048&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357930	386049821							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688168	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC2CCS(=O)(=O)CC2)n1	InChI=1S/C23H25N7O2S/c1-29-14-18(11-25-29)16-4-3-5-17(10-16)22-24-13-21(19-12-26-30(2)15-19)23(28-22)27-20-6-8-33(31,32)9-7-20/h3-5,10-15,20H,6-9H2,1-2H3,(H,24,27,28)	GMIYTDVUKKGWON-UHFFFAOYSA-N	348049	US9790221, Compound 257	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348049&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357931	386049822							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688170	CC(=O)N1CCCCC1CCNc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C27H32N8O/c1-19(36)35-12-5-4-9-24(35)10-11-28-27-25(23-15-31-34(3)18-23)16-29-26(32-27)21-8-6-7-20(13-21)22-14-30-33(2)17-22/h6-8,13-18,24H,4-5,9-12H2,1-3H3,(H,28,29,32)	MPOBKMHNZGARAK-UHFFFAOYSA-N	348050	US9790221, Compound 258	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348050&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357937	386049823							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688172	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCC2CCCCN2S(C)(=O)=O)n1	InChI=1S/C26H32N8O2S/c1-32-17-21(14-29-32)19-7-6-8-20(13-19)25-28-16-24(22-15-30-33(2)18-22)26(31-25)27-11-10-23-9-4-5-12-34(23)37(3,35)36/h6-8,13-18,23H,4-5,9-12H2,1-3H3,(H,27,28,31)	CPJKJLHVCDICJZ-UHFFFAOYSA-N	348051	US9790221, Compound 259	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348051&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357933	386049824							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688174	CC(C)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C21H23N7/c1-14(2)25-21-19(18-10-24-28(4)13-18)11-22-20(26-21)16-7-5-6-15(8-16)17-9-23-27(3)12-17/h5-14H,1-4H3,(H,22,25,26)	KJGJMKXKURZKFH-UHFFFAOYSA-N	348052	US9790221, Compound 260	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348052&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357934	386049825							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688176	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(CO)C1	InChI=1S/C23H25N7O/c1-28-13-19(9-25-28)17-4-3-5-18(8-17)22-24-11-21(20-10-26-29(2)14-20)23(27-22)30-7-6-16(12-30)15-31/h3-5,8-11,13-14,16,31H,6-7,12,15H2,1-2H3	GXZYPGJNTBKYLL-UHFFFAOYSA-N	348053	US9790221, Compound 261	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348053&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357932	386049826							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688178	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC2(CCCCC2)NS(C)(=O)=O)n1	InChI=1S/C26H32N8O2S/c1-33-16-21(13-29-33)19-8-7-9-20(12-19)24-27-15-23(22-14-30-34(2)17-22)25(31-24)28-18-26(32-37(3,35)36)10-5-4-6-11-26/h7-9,12-17,32H,4-6,10-11,18H2,1-3H3,(H,27,28,31)	LURSNEIGKLMDIQ-UHFFFAOYSA-N	348054	US9790221, Compound 262	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348054&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357938	386049827							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688180	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](CC2)N2CCOCC2)n1	InChI=1S/C28H34N8O/c1-34-18-22(15-30-34)20-4-3-5-21(14-20)27-29-17-26(23-16-31-35(2)19-23)28(33-27)32-24-6-8-25(9-7-24)36-10-12-37-13-11-36/h3-5,14-19,24-25H,6-13H2,1-2H3,(H,29,32,33)/t24-,25+	OTOZQHGGWWIOOP-PLQXJYEYSA-N	348055	US9790221, Compound 263	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348055&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357902	386049828							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688182	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(CN)C1	InChI=1S/C23H26N8/c1-29-14-19(10-26-29)17-4-3-5-18(8-17)22-25-12-21(20-11-27-30(2)15-20)23(28-22)31-7-6-16(9-24)13-31/h3-5,8,10-12,14-16H,6-7,9,13,24H2,1-2H3	MOFQFJLPAFFADX-UHFFFAOYSA-N	348056	US9790221, Compound 264	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348056&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357935	386049829							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688184	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CCC(CNS(C)(=O)=O)C1	InChI=1S/C24H28N8O2S/c1-30-15-20(11-26-30)18-5-4-6-19(9-18)23-25-13-22(21-12-27-31(2)16-21)24(29-23)32-8-7-17(14-32)10-28-35(3,33)34/h4-6,9,11-13,15-17,28H,7-8,10,14H2,1-3H3	AWFRNUOSRQGDHJ-UHFFFAOYSA-N	348057	US9790221, Compound 265	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348057&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357936	386049830							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688186	CC(=O)NC12CC(C1)(C2)Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1	InChI=1S/C25H26N8O/c1-16(34)30-24-13-25(14-24,15-24)31-23-21(20-9-28-33(3)12-20)10-26-22(29-23)18-6-4-5-17(7-18)19-8-27-32(2)11-19/h4-12H,13-15H2,1-3H3,(H,30,34)(H,26,29,31)	NBADYOMKUPUIOZ-UHFFFAOYSA-N	348058	US9790221, Compound 266	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348058&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360835	386049831							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688188	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCNS(C)(=O)=O)n1	InChI=1S/C21H24N8O2S/c1-28-13-17(10-24-28)15-5-4-6-16(9-15)20-23-12-19(18-11-25-29(2)14-18)21(27-20)22-7-8-26-32(3,30)31/h4-6,9-14,26H,7-8H2,1-3H3,(H,22,23,27)	CKWSTCUNVXJRFQ-UHFFFAOYSA-N	348059	US9790221, Compound 267	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348059&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360884	386049832							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688190	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@@H](O)[C@H]2O)n1	InChI=1S/C24H27N7O2/c1-30-13-17(10-26-30)15-5-3-6-16(9-15)23-25-12-19(18-11-27-31(2)14-18)24(29-23)28-20-7-4-8-21(32)22(20)33/h3,5-6,9-14,20-22,32-33H,4,7-8H2,1-2H3,(H,25,28,29)/t20-,21+,22-/m0/s1	UVHWQKYXRJARRI-BDTNDASRSA-N	348060	US9790221, Compound 268	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348060&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357940	386049833							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688192	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CC(N)(C2)C3)n1	InChI=1S/C23H24N8/c1-30-10-17(7-26-30)15-4-3-5-16(6-15)20-25-9-19(18-8-27-31(2)11-18)21(28-20)29-23-12-22(24,13-23)14-23/h3-11H,12-14,24H2,1-2H3,(H,25,28,29)	SRYKBJDUNDIEDT-UHFFFAOYSA-N	348061	US9790221, Compound 269	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348061&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357939	386049834							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688194	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NC23CC(C2)(C3)NS(C)(=O)=O)n1	InChI=1S/C24H26N8O2S/c1-31-11-18(8-26-31)16-5-4-6-17(7-16)21-25-10-20(19-9-27-32(2)12-19)22(28-21)29-23-13-24(14-23,15-23)30-35(3,33)34/h4-12,30H,13-15H2,1-3H3,(H,25,28,29)	FODHFBZBRDGSRC-UHFFFAOYSA-N	348062	US9790221, Compound 270	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348062&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360800	386049835							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688196	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC(F)(F)F)n1	InChI=1S/C20H18F3N7/c1-29-10-15(7-26-29)13-4-3-5-14(6-13)18-24-9-17(16-8-27-30(2)11-16)19(28-18)25-12-20(21,22)23/h3-11H,12H2,1-2H3,(H,24,25,28)	NOWCMVVSLQGVBT-UHFFFAOYSA-N	348063	US9790221, Compound 271	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348063	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348063&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357944	386049836							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688198	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC(F)(F)C(F)(F)C(F)(F)F)n1	InChI=1S/C22H18F7N7/c1-35-10-15(7-32-35)13-4-3-5-14(6-13)18-30-9-17(16-8-33-36(2)11-16)19(34-18)31-12-20(23,24)21(25,26)22(27,28)29/h3-11H,12H2,1-2H3,(H,30,31,34)	AFDWVDIRGUOXSE-UHFFFAOYSA-N	348064	US9790221, Compound 272	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348064	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348064&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357941	386049837							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688200	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](O)[C@@H]2O)n1	InChI=1S/C23H25N7O2/c1-29-12-16(9-25-29)14-4-3-5-15(8-14)22-24-11-18(17-10-26-30(2)13-17)23(28-22)27-19-6-7-20(31)21(19)32/h3-5,8-13,19-21,31-32H,6-7H2,1-2H3,(H,24,27,28)/t19-,20-,21+/m0/s1	SHIDRWICLBUMFI-PCCBWWKXSA-N	348065	US9790221, Compound 273	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348065	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348065&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357942	386049838							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688202	CC(Nc1nc(ncc1-c1cnn(C)c1)-c1cccc(c1)-c1cnn(C)c1)C1CCN(CC1)S(C)(=O)=O	InChI=1S/C26H32N8O2S/c1-18(19-8-10-34(11-9-19)37(4,35)36)30-26-24(23-14-29-33(3)17-23)15-27-25(31-26)21-7-5-6-20(12-21)22-13-28-32(2)16-22/h5-7,12-19H,8-11H2,1-4H3,(H,27,30,31)	TWGHPYFCGHSXBZ-UHFFFAOYSA-N	348066	US9790221, Compound 274	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348066&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357945	386049839							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688204	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCC(O)C(F)(F)F)n1	InChI=1S/C21H20F3N7O/c1-30-11-15(7-27-30)13-4-3-5-14(6-13)19-25-9-17(16-8-28-31(2)12-16)20(29-19)26-10-18(32)21(22,23)24/h3-9,11-12,18,32H,10H2,1-2H3,(H,25,26,29)	ACAPLENTFKTEMU-UHFFFAOYSA-N	348067	US9790221, Compound 275	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348067	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348067&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357943	386049840							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688206	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@@H](CC2)NS(=O)(=O)C2CC2)n1	InChI=1S/C27H32N8O2S/c1-34-16-20(13-29-34)18-4-3-5-19(12-18)26-28-15-25(21-14-30-35(2)17-21)27(32-26)31-22-6-8-23(9-7-22)33-38(36,37)24-10-11-24/h3-5,12-17,22-24,33H,6-11H2,1-2H3,(H,28,31,32)/t22-,23-	RTJFCHPKSSMXRR-YHBQERECSA-N	348068	US9790221, Compound 276	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348068	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348068&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121360912	386049841							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688208	CC(=O)N1CCC(O)(CNc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)CC1	InChI=1S/C26H30N8O2/c1-18(35)34-9-7-26(36,8-10-34)17-28-25-23(22-13-30-33(3)16-22)14-27-24(31-25)20-6-4-5-19(11-20)21-12-29-32(2)15-21/h4-6,11-16,36H,7-10,17H2,1-3H3,(H,27,28,31)	LHUBYRTWKIWVMJ-UHFFFAOYSA-N	348069	US9790221, Compound 277	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348069&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357947	386049842							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688210	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCS(N)(=O)=O)n1	InChI=1S/C20H22N8O2S/c1-27-12-16(9-24-27)14-4-3-5-15(8-14)19-23-11-18(17-10-25-28(2)13-17)20(26-19)22-6-7-31(21,29)30/h3-5,8-13H,6-7H2,1-2H3,(H2,21,29,30)(H,22,23,26)	JJZLPUGFTQKJLL-UHFFFAOYSA-N	348070	US9790221, Compound 278	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348070	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348070&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357946	386049843							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688212	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CC[C@H](CC2)C(O)=O)n1	InChI=1S/C25H27N7O2/c1-31-14-19(11-27-31)17-4-3-5-18(10-17)23-26-13-22(20-12-28-32(2)15-20)24(30-23)29-21-8-6-16(7-9-21)25(33)34/h3-5,10-16,21H,6-9H2,1-2H3,(H,33,34)(H,26,29,30)/t16-,21+	WOOXQOVNYHOKDD-NBEIKUQISA-N	348071	US9790221, Compound 279	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348071&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357948	386049844							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688214	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1CC[C@H](F)[C@@H](O)C1	InChI=1S/C23H24FN7O/c1-29-12-17(9-26-29)15-4-3-5-16(8-15)22-25-11-19(18-10-27-30(2)13-18)23(28-22)31-7-6-20(24)21(32)14-31/h3-5,8-13,20-21,32H,6-7,14H2,1-2H3/t20-,21-/m0/s1	PIWMQOZJLWYWSF-SFTDATJTSA-N	348072	US9790221, Compound 280	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348072	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348072&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357949	386049845							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688216	CN[C@H]1CCC[C@H](Nc2nc(ncc2-c2cnn(C)c2)-c2cccc(c2)-c2cnn(C)c2)[C@@H]1O	InChI=1S/C25H30N8O/c1-26-21-8-5-9-22(23(21)34)30-25-20(19-12-29-33(3)15-19)13-27-24(31-25)17-7-4-6-16(10-17)18-11-28-32(2)14-18/h4,6-7,10-15,21-23,26,34H,5,8-9H2,1-3H3,(H,27,30,31)/t21-,22-,23+/m0/s1	VVRUBFLZWRBKTA-RJGXRXQPSA-N	348073	US9790221, Compound 281	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348073&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347706	386049846							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688218	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(NCCCS(C)(=N)=O)n1	InChI=1S/C22H26N8OS/c1-29-14-18(11-26-29)16-6-4-7-17(10-16)21-25-13-20(19-12-27-30(2)15-19)22(28-21)24-8-5-9-32(3,23)31/h4,6-7,10-15,23H,5,8-9H2,1-3H3,(H,24,25,28)	PYNDPNVZINVDQN-UHFFFAOYSA-N	348074	US9790221, Compound 282	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348074&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121357950	386049847							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688220	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1C[C@H](N)CC(F)(F)C1	InChI=1S/C23H24F2N8/c1-31-11-17(8-28-31)15-4-3-5-16(6-15)21-27-10-20(18-9-29-32(2)12-18)22(30-21)33-13-19(26)7-23(24,25)14-33/h3-6,8-12,19H,7,13-14,26H2,1-2H3/t19-/m1/s1	MHPRLQWISRJHDD-LJQANCHMSA-N	348075	US9790221, Compound 283	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348075&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347734	386049848							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688222	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(n1)N1C[C@@H](N)CC(F)(F)C1	InChI=1S/C23H24F2N8/c1-31-11-17(8-28-31)15-4-3-5-16(6-15)21-27-10-20(18-9-29-32(2)12-18)22(30-21)33-13-19(26)7-23(24,25)14-33/h3-6,8-12,19H,7,13-14,26H2,1-2H3/t19-/m0/s1	MHPRLQWISRJHDD-IBGZPJMESA-N	348076	US9790221, Compound 284	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348076&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347753	386049849							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688224	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCC[C@H](F)[C@H]2O)n1	InChI=1S/C24H26FN7O/c1-31-13-17(10-27-31)15-5-3-6-16(9-15)23-26-12-19(18-11-28-32(2)14-18)24(30-23)29-21-8-4-7-20(25)22(21)33/h3,5-6,9-14,20-22,33H,4,7-8H2,1-2H3,(H,26,29,30)/t20-,21-,22+/m0/s1	ODTWEGAIGUDNQN-FDFHNCONSA-N	348077	US9790221, Compound 285	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348077&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347757	386049850							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688226	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CCC[C@@H](F)[C@@H]2O)n1	InChI=1S/C24H26FN7O/c1-31-13-17(10-27-31)15-5-3-6-16(9-15)23-26-12-19(18-11-28-32(2)14-18)24(30-23)29-21-8-4-7-20(25)22(21)33/h3,5-6,9-14,20-22,33H,4,7-8H2,1-2H3,(H,26,29,30)/t20-,21-,22+/m1/s1	ODTWEGAIGUDNQN-VSKRKVRLSA-N	348078	US9790221, Compound 286	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348078&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347805	386049851							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688228	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CCCC(F)(F)[C@H]2O)n1	InChI=1S/C24H25F2N7O/c1-32-13-17(10-28-32)15-5-3-6-16(9-15)22-27-12-19(18-11-29-33(2)14-18)23(31-22)30-20-7-4-8-24(25,26)21(20)34/h3,5-6,9-14,20-21,34H,4,7-8H2,1-2H3,(H,27,30,31)/t20-,21+/m1/s1	YQVAXHSIHKEXIY-RTWAWAEBSA-N	348079	US9790221, Compound 287	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348079&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347882	386049852							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688230	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@H]2CCCC[C@@H](O)[C@H]2O)n1	InChI=1S/C25H29N7O2/c1-31-14-18(11-27-31)16-6-5-7-17(10-16)24-26-13-20(19-12-28-32(2)15-19)25(30-24)29-21-8-3-4-9-22(33)23(21)34/h5-7,10-15,21-23,33-34H,3-4,8-9H2,1-2H3,(H,26,29,30)/t21-,22+,23-/m0/s1	JGAOGPNHVTXBLP-ZRBLBEILSA-N	348080	US9790221, Compound 288	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348080	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348080&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347794	386049853							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
688232	Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2cnn(C)c2)c(N[C@@H]2CCCC[C@H](O)[C@@H]2O)n1	InChI=1S/C25H29N7O2/c1-31-14-18(11-27-31)16-6-5-7-17(10-16)24-26-13-20(19-12-28-32(2)15-19)25(30-24)29-21-8-3-4-9-22(33)23(21)34/h5-7,10-15,21-23,33-34H,3-4,8-9H2,1-2H3,(H,26,29,30)/t21-,22+,23-/m1/s1	JGAOGPNHVTXBLP-XPWALMASSA-N	348081	US9790221, Compound 289	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q29S1T4F		aid1797398	US9790221	Jorand-Lebrun, C; Jones, R; Won, AC; Nguyen, N; Johnson, TL; Deselm, LC; Panda, K	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348081	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348081&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			121347881	386049854							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703725	Cn1cc2NC(=O)c3cccc(c3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C21H24N6O2/c1-26-14-18-19(25-26)21(29)22-9-4-2-3-5-10-27-13-17(12-23-27)15-7-6-8-16(11-15)20(28)24-18/h6-8,11-14H,2-5,9-10H2,1H3,(H,22,29)(H,24,28)	WYLVPVUYCUHITQ-UHFFFAOYSA-N	355816	US9815836, Compound 1	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355816&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472072	386395420							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703727	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCNC(=O)c2n1)c3	InChI=1S/C18H19N7O2/c1-24-11-15-16(23-24)18(27)19-7-2-3-8-25-10-12(9-20-25)13-5-4-6-14(21-13)17(26)22-15/h4-6,9-11H,2-3,7-8H2,1H3,(H,19,27)(H,22,26)	WHFKPHNLHTXXRK-UHFFFAOYSA-N	355817	US9815836, Compound 2::US9815836, Compound 4	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355817&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472074	386395421							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703729	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C20H23N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h6-8,11-13H,2-5,9-10H2,1H3,(H,21,29)(H,24,28)	DEQPRWCETBREMX-UHFFFAOYSA-N	355818	US9815836, Compound 3::US9815836, Compound 35	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355818&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472075	386395422							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703731	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCNC(=O)c2n1)c3	InChI=1S/C18H19N7O2/c1-24-11-15-16(23-24)18(27)19-7-2-3-8-25-10-12(9-20-25)13-5-4-6-14(21-13)17(26)22-15/h4-6,9-11H,2-3,7-8H2,1H3,(H,19,27)(H,22,26)	WHFKPHNLHTXXRK-UHFFFAOYSA-N	355817	US9815836, Compound 2::US9815836, Compound 4	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355817&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472074	386395421							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703733	CN1CCNC(=O)c2nn(C)cc2NC(=O)c2cccc(n2)-c2cnn(CCOC1=O)c2	InChI=1S/C20H22N8O4/c1-26-7-6-21-19(30)17-16(12-27(2)25-17)24-18(29)15-5-3-4-14(23-15)13-10-22-28(11-13)8-9-32-20(26)31/h3-5,10-12H,6-9H2,1-2H3,(H,21,30)(H,24,29)	IOGAJFHQVURNGY-UHFFFAOYSA-N	355820	US9815836, Compound 5	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355820&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472076	386395423							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703735	O=C1NCCCCCn2cc(cn2)-c2cccc(c2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C24H28N6O3/c31-23-18-6-4-5-17(13-18)19-14-26-29(15-19)10-3-1-2-9-25-24(32)22-21(27-23)16-30(28-22)20-7-11-33-12-8-20/h4-6,13-16,20H,1-3,7-12H2,(H,25,32)(H,27,31)	SYFRXWMCBTWRPE-UHFFFAOYSA-N	355821	US9815836, Compound 6	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355821&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472077	386395424							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703737	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCN4CCOC(C4)CNC(=O)c2n1)c3	InChI=1S/C21H24N8O3/c1-27-13-18-19(26-27)21(31)22-10-15-12-28(7-8-32-15)5-6-29-11-14(9-23-29)16-3-2-4-17(24-16)20(30)25-18/h2-4,9,11,13,15H,5-8,10,12H2,1H3,(H,22,31)(H,25,30)	SYYKHBVMTZVZNX-UHFFFAOYSA-N	355822	US9815836, Compound 7	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355822&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472080	386395425							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703739	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCOC(=O)N4CCOC(C4)CNC(=O)c2n1)c3	InChI=1S/C22H24N8O5/c1-28-13-18-19(27-28)21(32)23-10-15-12-29(5-7-34-15)22(33)35-8-6-30-11-14(9-24-30)16-3-2-4-17(25-16)20(31)26-18/h2-4,9,11,13,15H,5-8,10,12H2,1H3,(H,23,32)(H,26,31)	QJYCHNPBBAGVAL-UHFFFAOYSA-N	355823	US9815836, Compound 8	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355823&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472079	386395426							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703741	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCN4CCC(C4)CNC(=O)c2n1)c3	InChI=1S/C21H24N8O2/c1-27-13-18-19(26-27)21(31)22-9-14-5-6-28(11-14)7-8-29-12-15(10-23-29)16-3-2-4-17(24-16)20(30)25-18/h2-4,10,12-14H,5-9,11H2,1H3,(H,22,31)(H,25,30)	RDOTWECHZPUBFT-UHFFFAOYSA-N	355824	US9815836, Compound 9	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355824&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472082	386395427							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703743	CN1CCNC(=O)c2nn(C)cc2NC(=O)c2cccc(n2)-c2cnn(CC1)c2	InChI=1S/C19H22N8O2/c1-25-7-6-20-19(29)17-16(12-26(2)24-17)23-18(28)15-5-3-4-14(22-15)13-10-21-27(11-13)9-8-25/h3-5,10-12H,6-9H2,1-2H3,(H,20,29)(H,23,28)	SRPZQITYKMNCOH-UHFFFAOYSA-N	355825	US9815836, Compound 10	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355825&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472086	386395428							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703745	CN1CCCNC(=O)c2nn(C)cc2NC(=O)c2cccc(n2)-c2cnn(CC1)c2	InChI=1S/C20H24N8O2/c1-26-8-4-7-21-20(30)18-17(13-27(2)25-18)24-19(29)16-6-3-5-15(23-16)14-11-22-28(12-14)10-9-26/h3,5-6,11-13H,4,7-10H2,1-2H3,(H,21,30)(H,24,29)	REOARNJFSZRZAR-UHFFFAOYSA-N	355826	US9815836, Compound 11	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355826&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472081	386395429							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703747	O=C1NCCCCCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C24H29N7O3/c32-23-20-7-5-6-19(27-20)17-14-26-30(15-17)11-4-2-1-3-10-25-24(33)22-21(28-23)16-31(29-22)18-8-12-34-13-9-18/h5-7,14-16,18H,1-4,8-13H2,(H,25,33)(H,28,32)	KMRXRCNVWHQNQQ-UHFFFAOYSA-N	355827	US9815836, Compound 12	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355827&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472083	386395430							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703749	O=C1NCCSCCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C23H27N7O3S/c31-22-19-4-1-3-18(26-19)16-13-25-29(14-16)8-2-11-34-12-7-24-23(32)21-20(27-22)15-30(28-21)17-5-9-33-10-6-17/h1,3-4,13-15,17H,2,5-12H2,(H,24,32)(H,27,31)	WMIWTQABSHYHQO-UHFFFAOYSA-N	355828	US9815836, Compound 13	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355828&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472088	386395431							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703751	O=C1NCCS(=O)CCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C23H27N7O4S/c31-22-19-4-1-3-18(26-19)16-13-25-29(14-16)8-2-11-35(33)12-7-24-23(32)21-20(27-22)15-30(28-21)17-5-9-34-10-6-17/h1,3-4,13-15,17H,2,5-12H2,(H,24,32)(H,27,31)	XPYFVPXWJJIFIJ-UHFFFAOYSA-N	355829	US9815836, Compound 14	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355829&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472090	386395432							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703753	O=C1NCCS(=O)(=O)CCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C23H27N7O5S/c31-22-19-4-1-3-18(26-19)16-13-25-29(14-16)8-2-11-36(33,34)12-7-24-23(32)21-20(27-22)15-30(28-21)17-5-9-35-10-6-17/h1,3-4,13-15,17H,2,5-12H2,(H,24,32)(H,27,31)	WNIHRLHFZDFIJN-UHFFFAOYSA-N	355830	US9815836, Compound 15	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355830&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472087	386395433							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703755	O=C1NCCCCCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCNCC1	InChI=1S/C24H30N8O2/c33-23-20-7-5-6-19(28-20)17-14-27-31(15-17)13-4-2-1-3-10-26-24(34)22-21(29-23)16-32(30-22)18-8-11-25-12-9-18/h5-7,14-16,18,25H,1-4,8-13H2,(H,26,34)(H,29,33)	QSIQLKCEMDYCNP-UHFFFAOYSA-N	355831	US9815836, Compound 16	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355831&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472085	386395434							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703757	CS(=O)(=O)N1CCC(CC1)n1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C25H32N8O4S/c1-38(36,37)32-13-9-19(10-14-32)33-17-22-23(30-33)25(35)26-11-4-2-3-5-12-31-16-18(15-27-31)20-7-6-8-21(28-20)24(34)29-22/h6-8,15-17,19H,2-5,9-14H2,1H3,(H,26,35)(H,29,34)	DNKPCIXTLNUSBO-UHFFFAOYSA-N	355832	US9815836, Compound 17	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355832&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472091	386395435							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703759	FC1(F)CC1C(=O)N1CCC(CC1)n1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C28H32F2N8O3/c29-28(30)14-20(28)27(41)36-12-8-19(9-13-36)38-17-23-24(35-38)26(40)31-10-3-1-2-4-11-37-16-18(15-32-37)21-6-5-7-22(33-21)25(39)34-23/h5-7,15-17,19-20H,1-4,8-14H2,(H,31,40)(H,34,39)	AQLDNCJHOCPKMU-UHFFFAOYSA-N	355833	US9815836, Compound 18	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355833&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472089	386395436							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703761	O=C(NC1CC1)N1CCC(CC1)n1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C28H35N9O3/c38-26-23-7-5-6-22(32-23)19-16-30-36(17-19)13-4-2-1-3-12-29-27(39)25-24(33-26)18-37(34-25)21-10-14-35(15-11-21)28(40)31-20-8-9-20/h5-7,16-18,20-21H,1-4,8-15H2,(H,29,39)(H,31,40)(H,33,38)	CAAGOYXFXWKIHV-UHFFFAOYSA-N	355834	US9815836, Compound 19	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355834&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472095	386395437							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703763	O=C1NCCOCCn2cc(cn2)-c2cccc(c2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C23H26N6O4/c30-22-17-3-1-2-16(12-17)18-13-25-28(14-18)7-11-33-10-6-24-23(31)21-20(26-22)15-29(27-21)19-4-8-32-9-5-19/h1-3,12-15,19H,4-11H2,(H,24,31)(H,26,30)	CROQRZWPOTWTIY-UHFFFAOYSA-N	355835	US9815836, Compound 20	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355835&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472094	386395438							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703765	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCOC(=O)N4CCC(NC(=O)c2n1)C(O)C4)c3	InChI=1S/C22H24N8O5/c1-28-11-17-19(27-28)21(33)25-15-5-6-29(12-18(15)31)22(34)35-8-7-30-10-13(9-23-30)14-3-2-4-16(24-14)20(32)26-17/h2-4,9-11,15,18,31H,5-8,12H2,1H3,(H,25,33)(H,26,32)	WRTZYBOVKITHIR-UHFFFAOYSA-N	355836	US9815836, Compound 21	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355836&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472093	386395439							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703767	OCCN1CCC(CC1)n1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C26H34N8O3/c35-15-14-32-12-8-20(9-13-32)34-18-23-24(31-34)26(37)27-10-3-1-2-4-11-33-17-19(16-28-33)21-6-5-7-22(29-21)25(36)30-23/h5-7,16-18,20,35H,1-4,8-15H2,(H,27,37)(H,30,36)	GETIDMCBQRRWBD-UHFFFAOYSA-N	355837	US9815836, Compound 22	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355837&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472096	386395440							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703769	CN(C)CCN1CCC(CC1)n1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C28H39N9O2/c1-34(2)16-17-35-14-10-22(11-15-35)37-20-25-26(33-37)28(39)29-12-5-3-4-6-13-36-19-21(18-30-36)23-8-7-9-24(31-23)27(38)32-25/h7-9,18-20,22H,3-6,10-17H2,1-2H3,(H,29,39)(H,32,38)	KEOYWHZJNCXELX-UHFFFAOYSA-N	355838	US9815836, Compound 23	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355838&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472098	386395441							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703771	O=C1NCCCCCCn2cc(cn2)-c2cccc(c2)C(=O)Nc2cn(nc12)C1CCOCC1	InChI=1S/C25H30N6O3/c32-24-19-7-5-6-18(14-19)20-15-27-30(16-20)11-4-2-1-3-10-26-25(33)23-22(28-24)17-31(29-23)21-8-12-34-13-9-21/h5-7,14-17,21H,1-4,8-13H2,(H,26,33)(H,28,32)	MLZSRIZQAVOSJV-UHFFFAOYSA-N	355839	US9815836, Compound 24	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355839&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472097	386395442							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703773	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(C\C=C\CCCNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h3,5-8,11-13H,2,4,9-10H2,1H3,(H,21,29)(H,24,28)/b5-3+	LUZCLIOCMADQAB-HWKANZROSA-N	355840	US9815836, Compound 25	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355840&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472101	386395443							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703775	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CC\C=C/CCNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h2-3,6-8,11-13H,4-5,9-10H2,1H3,(H,21,29)(H,24,28)/b3-2-	SNFNJAIZBNSLET-IHWYPQMZSA-N	355841	US9815836, Compound 27	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355841&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472102	386395444							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703777	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CC\C=C\CCNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h2-3,6-8,11-13H,4-5,9-10H2,1H3,(H,21,29)(H,24,28)/b3-2+	SNFNJAIZBNSLET-NSCUHMNNSA-N	355842	US9815836, Compound 28	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355842&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472100	386395445							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703779	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCC\C=C\CNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h2,4,6-8,11-13H,3,5,9-10H2,1H3,(H,21,29)(H,24,28)/b4-2+	VFKSBPDPFVEQDD-DUXPYHPUSA-N	355843	US9815836, Compound 29::US9815836, Compound 34	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355843&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472104	386395446							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703781	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCC\C=C/CNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h2,4,6-8,11-13H,3,5,9-10H2,1H3,(H,21,29)(H,24,28)/b4-2-	VFKSBPDPFVEQDD-RQOWECAXSA-N	355844	US9815836, Compound 30	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355844&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472103	386395447							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703783	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCC(O)C(O)CNC(=O)c2n1)c3	InChI=1S/C20H23N7O4/c1-26-11-15-18(25-26)20(31)21-9-17(29)16(28)6-3-7-27-10-12(8-22-27)13-4-2-5-14(23-13)19(30)24-15/h2,4-5,8,10-11,16-17,28-29H,3,6-7,9H2,1H3,(H,21,31)(H,24,30)	FVYUSYCCSKFISZ-UHFFFAOYSA-N	355845	US9815836, Compound 31::US9815836, Compound 36	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355845&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472106	386395448							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703785	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CC(O)C(O)CCCNC(=O)c2n1)c3	InChI=1S/C20H23N7O4/c1-26-10-15-18(25-26)20(31)21-7-3-6-16(28)17(29)11-27-9-12(8-22-27)13-4-2-5-14(23-13)19(30)24-15/h2,4-5,8-10,16-17,28-29H,3,6-7,11H2,1H3,(H,21,31)(H,24,30)	AOMLTNPOZVEKEN-UHFFFAOYSA-N	355846	US9815836, Compound 32	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355846&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472105	386395449							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703787	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCC(O)C(O)CCNC(=O)c2n1)c3	InChI=1S/C20H23N7O4/c1-26-11-15-18(25-26)20(31)21-7-5-16(28)17(29)6-8-27-10-12(9-22-27)13-3-2-4-14(23-13)19(30)24-15/h2-4,9-11,16-17,28-29H,5-8H2,1H3,(H,21,31)(H,24,30)	QPEFRSUIXIWDNX-UHFFFAOYSA-N	355847	US9815836, Compound 33	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355847&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472107	386395450							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703789	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCC\C=C\CNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h2,4,6-8,11-13H,3,5,9-10H2,1H3,(H,21,29)(H,24,28)/b4-2+	VFKSBPDPFVEQDD-DUXPYHPUSA-N	355843	US9815836, Compound 29::US9815836, Compound 34	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355843&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472104	386395446							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703791	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3	InChI=1S/C20H23N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h6-8,11-13H,2-5,9-10H2,1H3,(H,21,29)(H,24,28)	DEQPRWCETBREMX-UHFFFAOYSA-N	355818	US9815836, Compound 3::US9815836, Compound 35	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355818&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472075	386395422							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703793	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCC(O)C(O)CNC(=O)c2n1)c3	InChI=1S/C20H23N7O4/c1-26-11-15-18(25-26)20(31)21-9-17(29)16(28)6-3-7-27-10-12(8-22-27)13-4-2-5-14(23-13)19(30)24-15/h2,4-5,8,10-11,16-17,28-29H,3,6-7,9H2,1H3,(H,21,31)(H,24,30)	FVYUSYCCSKFISZ-UHFFFAOYSA-N	355845	US9815836, Compound 31::US9815836, Compound 36	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355845&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472106	386395448							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703795	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(C\C=C/CCCNC(=O)c2n1)c3	InChI=1S/C20H21N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h3,5-8,11-13H,2,4,9-10H2,1H3,(H,21,29)(H,24,28)/b5-3-	LUZCLIOCMADQAB-HYXAFXHYSA-N	355851	US9815836, Compound 37	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355851&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472111	386395451							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
703797	Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CC#CCCCNC(=O)c2n1)c3	InChI=1S/C20H19N7O2/c1-26-13-17-18(25-26)20(29)21-9-4-2-3-5-10-27-12-14(11-22-27)15-7-6-8-16(23-15)19(28)24-17/h6-8,11-13H,2,4,9-10H2,1H3,(H,21,29)(H,24,28)	BNBWQHVAKHOGPJ-UHFFFAOYSA-N	355852	US9815836, Compound 38	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2CZ39FC		aid1797616	US9815836	Chen, X; Yu, H; Lan, R; Jorand-Lebrun, C; Johnson, TL; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=355852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=355852&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122472112	386395452							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856926	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C20H20N6O4/c1-25-12-15-18(24-25)20(29)21-8-3-9-30-16-6-7-17(27)26(23-16)11-13-4-2-5-14(10-13)19(28)22-15/h2,4-7,10,12H,3,8-9,11H2,1H3,(H,21,29)(H,22,28)	GKSLYGBWVIREPH-UHFFFAOYSA-N	318823	US10517872, Compound 1::US9624246, Compound 1	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318823&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447249	384222112							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856928	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cnn(CCNC(=O)c2n1)c4)c3	InChI=1S/C22H20N8O3/c1-28-13-18-20(27-28)22(33)23-7-8-29-12-16(10-24-29)17-5-6-19(31)30(26-17)11-14-3-2-4-15(9-14)21(32)25-18/h2-6,9-10,12-13H,7-8,11H2,1H3,(H,23,33)(H,25,32)	WGAIHKWWBXYAKM-UHFFFAOYSA-N	318825	US10517872, Compound 2::US9624246, Compound 2	Interleukin-1 receptor-associated kinase 1 [194-712]			<100							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318825&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470005	384222114							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856930	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cncc(CNC(=O)c2n1)c4)c3	InChI=1S/C23H19N7O3/c1-29-13-19-21(28-29)23(33)25-10-15-8-17(11-24-9-15)18-5-6-20(31)30(27-18)12-14-3-2-4-16(7-14)22(32)26-19/h2-9,11,13H,10,12H2,1H3,(H,25,33)(H,26,32)	OWGPCYDHMUISML-UHFFFAOYSA-N	318826	US10517872, Compound 3::US9624246, Compound 3	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318826&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470030	384222115							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856932	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C19H18N6O4/c1-24-11-14-17(23-24)19(28)20-7-8-29-15-5-6-16(26)25(22-15)10-12-3-2-4-13(9-12)18(27)21-14/h2-6,9,11H,7-8,10H2,1H3,(H,20,28)(H,21,27)	ATLIZTAFGKXPLE-UHFFFAOYSA-N	318827	US10517872, Compound 4::US9624246, Compound 4	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318827&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470006	384222116							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856934	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C21H22N6O4/c1-26-13-16-19(25-26)21(30)22-9-2-3-10-31-17-7-8-18(28)27(24-17)12-14-5-4-6-15(11-14)20(29)23-16/h4-8,11,13H,2-3,9-10,12H2,1H3,(H,22,30)(H,23,29)	XHWNTEWYWFMZBL-UHFFFAOYSA-N	318828	US10517872, Compound 5::US9624246, Compound 5	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318828&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447240	384222117							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856936	O=C1NCCCOc2ccc(=O)n(Cc3cccc(c3)C(=O)Nc3cn(nc13)C1CCOCC1)n2	InChI=1S/C24H26N6O5/c31-21-6-5-20-27-30(21)14-16-3-1-4-17(13-16)23(32)26-19-15-29(18-7-11-34-12-8-18)28-22(19)24(33)25-9-2-10-35-20/h1,3-6,13,15,18H,2,7-12,14H2,(H,25,33)(H,26,32)	WJPDPEBXKRAWLO-UHFFFAOYSA-N	318829	US10517872, Compound 6::US9624246, Compound 6	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318829&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470008	384222118							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856938	CC(C)(C)n1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)c3	InChI=1S/C23H26N6O4/c1-23(2,3)29-14-17-20(27-29)22(32)24-10-5-11-33-18-8-9-19(30)28(26-18)13-15-6-4-7-16(12-15)21(31)25-17/h4,6-9,12,14H,5,10-11,13H2,1-3H3,(H,24,32)(H,25,31)	XMDZLJRPNPTNNM-UHFFFAOYSA-N	318830	US10517872, Compound 7::US9624246, Compound 7	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318830&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470039	384222119							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856940	Cn1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)n3	InChI=1S/C19H19N7O4/c1-25-11-14-17(24-25)19(29)20-8-3-9-30-15-6-7-16(27)26(23-15)10-12-4-2-5-13(21-12)18(28)22-14/h2,4-7,11H,3,8-10H2,1H3,(H,20,29)(H,22,28)	JTDOHCWXAJEHMM-UHFFFAOYSA-N	318831	US10517872, Compound 8::US9624246, Compound 8	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318831&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122447275	384222120							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856942	O=C1NCCCOc2ccc(=O)n(Cc3cccc(n3)C(=O)Nc3cn(nc13)C1CCOCC1)n2	InChI=1S/C23H25N7O5/c31-20-6-5-19-27-30(20)13-15-3-1-4-17(25-15)22(32)26-18-14-29(16-7-11-34-12-8-16)28-21(18)23(33)24-9-2-10-35-19/h1,3-6,14,16H,2,7-13H2,(H,24,33)(H,26,32)	VWMDHJMEUZNQNF-UHFFFAOYSA-N	318832	US10517872, Compound 9::US9624246, Compound 9	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318832&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122471471	384222121							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856944	CC(C)(C)n1cc2NC(=O)c3cccc(Cn4nc(OCCCNC(=O)c2n1)ccc4=O)n3	InChI=1S/C22H25N7O4/c1-22(2,3)29-13-16-19(27-29)21(32)23-10-5-11-33-17-8-9-18(30)28(26-17)12-14-6-4-7-15(24-14)20(31)25-16/h4,6-9,13H,5,10-12H2,1-3H3,(H,23,32)(H,25,31)	AHFFIIHDSQMDME-UHFFFAOYSA-N	318833	US10517872, Compound 10::US9624246, Compound 10	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318833&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470054	384222122							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856946	OC1CNC(=O)c2nn(cc2NC(=O)c2cccc(Cn3nc(OC1)ccc3=O)n2)C1CCOCC1	InChI=1S/C23H25N7O6/c31-16-10-24-23(34)21-18(12-29(28-21)15-6-8-35-9-7-15)26-22(33)17-3-1-2-14(25-17)11-30-20(32)5-4-19(27-30)36-13-16/h1-5,12,15-16,31H,6-11,13H2,(H,24,34)(H,26,33)	KMOSRUDBPHUJJQ-UHFFFAOYSA-N	424931	US10517872, Compound 11	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=424931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=424931&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			129265101	434319324							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856948	Cn1cc2NC(=O)c3cccc(Cn4nc(OCC(O)CNC(=O)c2n1)ccc4=O)c3	InChI=1S/C20H20N6O5/c1-25-10-15-18(24-25)20(30)21-8-14(27)11-31-16-5-6-17(28)26(23-16)9-12-3-2-4-13(7-12)19(29)22-15/h2-7,10,14,27H,8-9,11H2,1H3,(H,21,30)(H,22,29)	FNRWLDQIJWSZPQ-UHFFFAOYSA-N	318835	US10517872, Compound 12::US9624246, Compound 12	Interleukin-1 receptor-associated kinase 1 [194-712]			 3000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318835&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470009	384222124							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856950	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4ccnc(CNC(=O)c2n1)c4)c3	InChI=1S/C23H19N7O3/c1-29-13-19-21(28-29)23(33)25-11-17-10-15(7-8-24-17)18-5-6-20(31)30(27-18)12-14-3-2-4-16(9-14)22(32)26-19/h2-10,13H,11-12H2,1H3,(H,25,33)(H,26,32)	ZGPAYCQEDZYSFA-UHFFFAOYSA-N	318836	US10517872, Compound 13::US9624246, Compound 13	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318836&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470010	384222125							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856952	Cn1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc(CCNC(=O)c2n1)c4)c3	InChI=1S/C25H22N6O3/c1-30-15-21-23(29-30)25(34)26-11-10-16-4-2-6-18(12-16)20-8-9-22(32)31(28-20)14-17-5-3-7-19(13-17)24(33)27-21/h2-9,12-13,15H,10-11,14H2,1H3,(H,26,34)(H,27,33)	ZZPZTQIZEUBASL-UHFFFAOYSA-N	318837	US10517872, Compound 14::US9624246, Compound 14	Interleukin-1 receptor-associated kinase 1 [194-712]			 550							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318837&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			122470003	384222126							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2						
856954	Cc1cc2NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc(CCn2n1)c4)c3	InChI=1S/C24H21N5O2/c1-16-12-22-25-24(31)20-7-3-5-18(14-20)15-29-23(30)9-8-21(27-29)19-6-2-4-17(13-19)10-11-28(22)26-16/h2-9,12-14H,10-11,15H2,1H3,(H,25,31)	SANOXDVEBDNEDL-UHFFFAOYSA-N	318838	US10517872, Compound 15::US9624246, Compound 15	Interleukin-1 receptor-associated kinase 1 [194-712]			>5000							US Patent		10.7270/Q2SN0CCS		aid1804063	US10517872	Chen, X; Lan, R; Jorand-Lebrun, C; Yu, H; Goutopoulos, A	Merck Patent GmbH	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=318838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=541&target=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=318838&enzyme=Interleukin-1+receptor-associated+kinase+1+%5B194-712%5D&column=ki&startPg=0&Increment=50&submit=Search			137138406	384222127							1	RPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS	6BFN	Interleukin-1 receptor-associated kinase 1	IRAK1_HUMAN	P51617	D3DWW3 D3DWW4 Q7Z5V4 Q96C06 Q96RL2