BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 8100 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(N)=O)c1nc(Cc2ccccc2)no1 InChI=1S/C24H28N5O8P/c1-15(30)26-20(13-17-7-9-18(10-8-17)37-38(33,34)35)23(32)27-19(11-12-21(25)31)24-28-22(29-36-24)14-16-5-3-2-4-6-16/h2-10,19-20H,11-14H2,1H3,(H2,25,31)(H,26,30)(H,27,32)(H2,33,34,35)/t19-,20-/m0/s1 QORDHESRPJEYMQ-PMACEKPBSA-N 5092 1,2,4-Oxadiazole Analogue 4a::4-[(2S)-2-{[(1S)-1-(3-benzyl-1,2,4-oxadiazol-5-yl)-3-carbamoylpropyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid::CHEMBL77067 Growth factor receptor-bound protein 2 Homo sapiens 456000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5092&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329214 8034731 CHEMBL77067 C01167 ZINC14944824 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8101 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(N)=O)c1nc(Cc2ccc(Cl)c(Cl)c2)no1 InChI=1S/C24H26Cl2N5O8P/c1-13(32)28-20(11-14-2-5-16(6-3-14)39-40(35,36)37)23(34)29-19(8-9-21(27)33)24-30-22(31-38-24)12-15-4-7-17(25)18(26)10-15/h2-7,10,19-20H,8-9,11-12H2,1H3,(H2,27,33)(H,28,32)(H,29,34)(H2,35,36,37)/t19-,20-/m0/s1 HKOHWDTYCZDWEW-PMACEKPBSA-N 5093 1,2,4-Oxadiazole Analogue 4f::4-[(2S)-2-{[(1S)-3-carbamoyl-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 441000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5093&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329215 8034732 C01167 ZINC14944826 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8102 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(N)=O)c1nc(Cc2ccc3ccccc3c2)no1 InChI=1S/C28H30N5O8P/c1-17(34)30-24(15-18-7-10-22(11-8-18)41-42(37,38)39)27(36)31-23(12-13-25(29)35)28-32-26(33-40-28)16-19-6-9-20-4-2-3-5-21(20)14-19/h2-11,14,23-24H,12-13,15-16H2,1H3,(H2,29,35)(H,30,34)(H,31,36)(H2,37,38,39)/t23-,24-/m0/s1 SORYSZMOIUVUTP-ZEQRLZLVSA-N 5094 1,2,4-Oxadiazole Analogue 4j::4-[(2S)-2-{[(1S)-3-carbamoyl-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]propyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 327000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5094&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329216 8034733 C01167 ZINC14944828 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8103 C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc(Cl)c(Cl)c2)no1 InChI=1S/C22H23Cl2N4O7P/c1-12(22-27-20(28-34-22)11-15-5-8-17(23)18(24)9-15)25-21(30)19(26-13(2)29)10-14-3-6-16(7-4-14)35-36(31,32)33/h3-9,12,19H,10-11H2,1-2H3,(H,25,30)(H,26,29)(H2,31,32,33)/t12-,19-/m0/s1 CBNCEXIXRUFMGU-BUXKBTBVSA-N 5095 1,2,4-Oxadiazole Analogue 5d::4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid::CHEMBL318300 Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5095&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329217 8034734 CHEMBL318300 C01167 ZINC14944830 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8104 C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc3ccccc3c2)no1 InChI=1S/C26H27N4O7P/c1-16(26-29-24(30-36-26)15-19-7-10-20-5-3-4-6-21(20)13-19)27-25(32)23(28-17(2)31)14-18-8-11-22(12-9-18)37-38(33,34)35/h3-13,16,23H,14-15H2,1-2H3,(H,27,32)(H,28,31)(H2,33,34,35)/t16-,23-/m0/s1 BOPDYYROOJKDMG-HJPURHCSSA-N 5096 1,2,4-Oxadiazole Analogue 5e::4-[(2S)-2-acetamido-2-{[(1S)-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl}ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5096&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329218 8034735 C01167 ZINC14944832 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8105 C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 InChI=1S/C23H24F3N4O7P/c1-13(22-29-20(30-36-22)12-16-3-7-17(8-4-16)23(24,25)26)27-21(32)19(28-14(2)31)11-15-5-9-18(10-6-15)37-38(33,34)35/h3-10,13,19H,11-12H2,1-2H3,(H,27,32)(H,28,31)(H2,33,34,35)/t13-,19-/m0/s1 KVCLASFFEYSLKL-DJJJIMSYSA-N 5097 1,2,4-Oxadiazole Analogue 5f::4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid::CHEMBL103838 Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5097&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 6326464 8034736 CHEMBL103838 C01167 ZINC03981533 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8106 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CO)c1nc(Cc2ccc(Cl)c(Cl)c2)no1 InChI=1S/C22H23Cl2N4O8P/c1-12(30)25-18(9-13-2-5-15(6-3-13)36-37(32,33)34)21(31)26-19(11-29)22-27-20(28-35-22)10-14-4-7-16(23)17(24)8-14/h2-8,18-19,29H,9-11H2,1H3,(H,25,30)(H,26,31)(H2,32,33,34)/t18-,19-/m0/s1 BVFIVGIHHLRXBD-OALUTQOASA-N 5098 1,2,4-Oxadiazole Analogue 12b::4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid::CHEMBL316967 Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5098&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329220 8034737 CHEMBL316967 C01167 ZINC14944834 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8107 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CO)c1nc(Cc2ccc3ccccc3c2)no1 InChI=1S/C26H27N4O8P/c1-16(32)27-22(13-17-7-10-21(11-8-17)38-39(34,35)36)25(33)28-23(15-31)26-29-24(30-37-26)14-18-6-9-19-4-2-3-5-20(19)12-18/h2-12,22-23,31H,13-15H2,1H3,(H,27,32)(H,28,33)(H2,34,35,36)/t22-,23-/m0/s1 UFTIYCGIXVQLSR-GOTSBHOMSA-N 5099 1,2,4-Oxadiazole Analogue 12c::4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl}ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 479000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5099&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329221 8034738 C01167 ZINC14944836 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8108 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CO)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 InChI=1S/C23H24F3N4O8P/c1-13(32)27-18(10-14-4-8-17(9-5-14)38-39(34,35)36)21(33)28-19(12-31)22-29-20(30-37-22)11-15-2-6-16(7-3-15)23(24,25)26/h2-9,18-19,31H,10-12H2,1H3,(H,27,32)(H,28,33)(H2,34,35,36)/t18-,19-/m0/s1 YAHVNVAURPCRLK-OALUTQOASA-N 5100 1,2,4-Oxadiazole Analogue 12d::4-[(2S)-2-acetamido-2-{[(1S)-2-hydroxy-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5100&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329222 8034739 C01167 ZINC14944838 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8109 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCc1ccccc1)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 InChI=1S/C30H30F3N4O7P/c1-19(38)34-26(17-21-9-14-24(15-10-21)44-45(40,41)42)28(39)35-25(16-11-20-5-3-2-4-6-20)29-36-27(37-43-29)18-22-7-12-23(13-8-22)30(31,32)33/h2-10,12-15,25-26H,11,16-18H2,1H3,(H,34,38)(H,35,39)(H2,40,41,42)/t25-,26-/m0/s1 QMRZIGJBOKWGSJ-UIOOFZCWSA-N 5101 1,2,4-Oxadiazole Analogue 13a::4-[(2S)-2-acetamido-2-{[(1S)-3-phenyl-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)propyl]carbamoyl}ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5101&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329223 8034740 C01167 ZINC27330296 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8110 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCc1ccccc1)c1nc(Cc2ccc3ccccc3c2)no1 InChI=1S/C33H33N4O7P/c1-22(38)34-30(20-24-12-16-28(17-13-24)44-45(40,41)42)32(39)35-29(18-14-23-7-3-2-4-8-23)33-36-31(37-43-33)21-25-11-15-26-9-5-6-10-27(26)19-25/h2-13,15-17,19,29-30H,14,18,20-21H2,1H3,(H,34,38)(H,35,39)(H2,40,41,42)/t29-,30-/m0/s1 QTYKSUZAVYPFNL-KYJUHHDHSA-N 5102 1,2,4-Oxadiazole Analogue 13b::4-[(2S)-2-acetamido-2-{[(1S)-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]-3-phenylpropyl]carbamoyl}ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5102&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329224 8034741 C01167 ZINC14944841 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8111 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCc1ccccc1)c1nc(Cc2ccc(Cl)c(Cl)c2)no1 InChI=1S/C29H29Cl2N4O7P/c1-18(36)32-26(16-20-7-11-22(12-8-20)42-43(38,39)40)28(37)33-25(14-10-19-5-3-2-4-6-19)29-34-27(35-41-29)17-21-9-13-23(30)24(31)15-21/h2-9,11-13,15,25-26H,10,14,16-17H2,1H3,(H,32,36)(H,33,37)(H2,38,39,40)/t25-,26-/m0/s1 KFDCVBWXWCZIOI-UIOOFZCWSA-N 5103 1,2,4-Oxadiazole Analogue 13c::4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-3-phenylpropyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 340000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5103&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329225 8034742 C01167 ZINC27330577 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8112 OC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)c1nc(Cc2ccc(cc2)C(F)(F)F)no1 InChI=1S/C29H28F3N4O8P/c30-29(31,32)21-10-6-20(7-11-21)15-25-35-28(43-36-25)24(17-37)34-27(39)23(33-26(38)16-18-4-2-1-3-5-18)14-19-8-12-22(13-9-19)44-45(40,41)42/h1-13,23-24,37H,14-17H2,(H,33,38)(H,34,39)(H2,40,41,42)/t23-,24-/m0/s1 ZZBVBSSABXAMFR-ZEQRLZLVSA-N 5104 1,2,4-Oxadiazole Analogue 15a::4-[(2S)-2-{[(1S)-2-hydroxy-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}-2-(1-phenylacetamido)ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >500000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5104&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329226 8034743 C01167 ZINC27408391 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8113 OC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)c1nc(Cc2ccc(Cl)c(Cl)c2)no1 InChI=1S/C28H27Cl2N4O8P/c29-21-11-8-19(12-22(21)30)14-25-33-28(41-34-25)24(16-35)32-27(37)23(31-26(36)15-17-4-2-1-3-5-17)13-18-6-9-20(10-7-18)42-43(38,39)40/h1-12,23-24,35H,13-16H2,(H,31,36)(H,32,37)(H2,38,39,40)/t23-,24-/m0/s1 OBKJDPLCBADFLQ-ZEQRLZLVSA-N 5105 1,2,4-Oxadiazole Analogue 15b::4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}-2-(1-phenylacetamido)ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 263000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5105&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329227 8034744 C01167 ZINC27416998 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 8114 OC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)c1nc(Cc2ccc3ccccc3c2)no1 InChI=1S/C32H31N4O8P/c37-20-28(32-35-29(36-43-32)18-23-10-13-24-8-4-5-9-25(24)16-23)34-31(39)27(33-30(38)19-21-6-2-1-3-7-21)17-22-11-14-26(15-12-22)44-45(40,41)42/h1-16,27-28,37H,17-20H2,(H,33,38)(H,34,39)(H2,40,41,42)/t27-,28-/m0/s1 RRNYTUGEKKWGTI-NSOVKSMOSA-N 5106 1,2,4-Oxadiazole Analogue 15c::4-[(2S)-2-{[(1S)-2-hydroxy-1-[3-(naphthalen-2-ylmethyl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl}-2-(1-phenylacetamido)ethyl]phenoxyphosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 368000 Curated from the literature by BindingDB 10.1021/jm990229t 10.7270/Q27D2SBP 10514279 aid1795733 Vu, CB; Corpuz, EG; Merry, TJ; Pradeepan, SG; Bartlett, C; Bohacek, RS; Botfield, MC; Eyermann, CJ; Lynch, BA; MacNeil, IA; Ram, MK; van Schravendijk, MR; Violette, S; Sawyer, TK ARIAD Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5106&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5329228 8034745 C01167 ZINC27408697 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50017358 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)N=[N+]=[N-])C(=O)NCCCc1cccc2ccccc12 InChI=1S/C34H42N7O7P/c35-30(42)21-28(31(43)37-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)38-33(45)34(17-4-1-5-18-34)39-32(44)29(40-41-36)20-23-13-15-24(16-14-23)22-49(46,47)48/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,35,42)(H,37,43)(H,38,45)(H,39,44)(H2,46,47,48)/t28-,29-/m0/s1 OMNUIMNPAZIAAP-VMPREFPWSA-N 50118686 CHEMBL323505::[(S)-3-(2-Azido-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >30000 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118686&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44326935 104011950 CHEMBL323505 ZINC36761376 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50017359 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H45N4O9P/c37-31(41)22-30(34(45)38-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27)39-35(46)36(17-4-1-5-18-36)40-33(44)28(21-32(42)43)20-24-13-15-25(16-14-24)23-50(47,48)49/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1 AYRBFDFQLSQIBI-DGPALRBDSA-N 50118687 (R)-N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-(4-phosphonomethyl-benzyl)-succinamic acid::CHEMBL93367::N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-((R)-3-phosphonomethyl-benzyl)-succinamic acid Growth factor receptor-bound protein 2 Homo sapiens 10000 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118687&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987336 104011951 CHEMBL93367 ZINC26663353 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50017360 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 9 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50020397 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 BZLRZJFFHMIABH-AGEHIQCHSA-N 50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide Growth factor receptor-bound protein 2 Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124303&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383302 104016640 CHEMBL444114 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50020398 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)(C)C)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C60H86N12O19S/c1-30(2)21-37-49(79)68-39(23-33-13-17-35(74)18-14-33)54(84)72-60(19-9-8-10-20-60)58(90)70-41(25-44(61)75)52(82)71-47(31(3)4)55(85)63-27-45(76)65-42(26-59(5,6)7)53(83)67-38(22-32-11-15-34(73)16-12-32)50(80)69-43(48(62)78)28-92(91)29-46(77)64-40(51(81)66-37)24-36(56(86)87)57(88)89/h11-18,30-31,36-43,47,73-74H,8-10,19-29H2,1-7H3,(H2,61,75)(H2,62,78)(H,63,85)(H,64,77)(H,65,76)(H,66,81)(H,67,83)(H,68,79)(H,69,80)(H,70,90)(H,71,82)(H,72,84)(H,86,87)(H,88,89)/t37-,38+,39+,40+,41+,42-,43+,47-,92?/m1/s1 FATUOQLOUJCJQH-CBHDNGEDSA-N 50129417 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys(O) NH2)::CHEMBL437456 Growth factor receptor-bound protein 2 Homo sapiens 74.6 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129417&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309241 104021000 CHEMBL437456 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50020399 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C66H84N12O19S/c1-34(2)24-44-56(85)74-47(27-37-15-20-42(80)21-16-37)61(90)78-66(22-8-5-9-23-66)65(96)76-49(30-51(67)81)60(89)77-54(35(3)4)62(91)69-31-52(82)70-45(28-38-12-17-39-10-6-7-11-40(39)25-38)57(86)73-46(26-36-13-18-41(79)19-14-36)58(87)75-50(55(68)84)32-98(97)33-53(83)71-48(59(88)72-44)29-43(63(92)93)64(94)95/h6-7,10-21,25,34-35,43-50,54,79-80H,5,8-9,22-24,26-33H2,1-4H3,(H2,67,81)(H2,68,84)(H,69,91)(H,70,82)(H,71,83)(H,72,88)(H,73,86)(H,74,85)(H,75,87)(H,76,96)(H,77,89)(H,78,90)(H,92,93)(H,94,95)/t44-,45-,46+,47+,48+,49+,50+,54-,98?/m1/s1 SOAXVHRFUPUPAJ-OGJGZJPRSA-N 50129418 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Nal Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Nal Tyr Cys(O) NH2)::CHEMBL411790 Growth factor receptor-bound protein 2 Homo sapiens 4860 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129418&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309121 104021001 CHEMBL411790 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50043792 CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC(=O)[C@H](CC(N)=O)NC(C)=O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(N)=O InChI=1S/C38H55N9O16/c1-6-17(4)29(36(58)43-21(31(41)53)11-12-27(51)52)47-34(56)24(15-26(40)50)45-35(57)28(16(2)3)46-33(55)22(44-32(54)23(14-25(39)49)42-18(5)48)13-19-7-9-20(10-8-19)63-30(37(59)60)38(61)62/h7-10,16-17,21-24,28-30H,6,11-15H2,1-5H3,(H2,39,49)(H2,40,50)(H2,41,53)(H,42,48)(H,43,58)(H,44,54)(H,45,57)(H,46,55)(H,47,56)(H,51,52)(H,59,60)(H,61,62)/t17-,21-,22-,23-,24-,28-,29-/m0/s1 COCBNXYELMVAPZ-STPLCBLJSA-N 50029328 2-{4-[(S)-2-((S)-2-Acetylamino-3-carbamoyl-propionylamino)-2-((S)-1-{(S)-2-carbamoyl-1-[(1S,2S)-1-((S)-1-carbamoyl-3-carboxy-propylcarbamoyl)-2-methyl-butylcarbamoyl]-ethylcarbamoyl}-2-methyl-propylcarbamoyl)-ethyl]-phenoxy}-malonic acid::CHEMBL135252 Growth factor receptor-bound protein 2 Homo sapiens 120000 ChEMBL 10.1021/jm00021a016 10.7270/Q2HX1BP2 7473554 Ye, B; Akamatsu, M; Shoelson, SE; Wolf, G; Giorgetti-Peraldi, S; Yan, X; Roller, PP; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029328&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10772023 103938399 CHEMBL135252 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50043799 CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CC(N)=O)NC(C)=O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(N)=O InChI=1S/C35H54N9O15P/c1-6-17(4)29(35(55)40-21(30(38)50)11-12-27(48)49)44-33(53)24(15-26(37)47)42-34(54)28(16(2)3)43-32(52)22(41-31(51)23(14-25(36)46)39-18(5)45)13-19-7-9-20(10-8-19)59-60(56,57)58/h7-10,16-17,21-24,28-29H,6,11-15H2,1-5H3,(H2,36,46)(H2,37,47)(H2,38,50)(H,39,45)(H,40,55)(H,41,51)(H,42,54)(H,43,52)(H,44,53)(H,48,49)(H2,56,57,58)/t17-,21-,22-,23-,24-,28-,29-/m0/s1 XFENFMVKZHIRIB-STPLCBLJSA-N 50029335 (S)-4-[(2S,3S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carbamoyl-propionylamino)-3-(4-phosphonooxy-phenyl)-propionylamino]-3-methyl-butyrylamino}-3-carbamoyl-propionylamino)-3-methyl-pentanoylamino]-4-carbamoyl-butyric acid::CHEMBL133230 Growth factor receptor-bound protein 2 Homo sapiens 900 ChEMBL 10.1021/jm00021a016 10.7270/Q2HX1BP2 7473554 Ye, B; Akamatsu, M; Shoelson, SE; Wolf, G; Giorgetti-Peraldi, S; Yan, X; Roller, PP; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029335&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44356493 103938406 CHEMBL133230 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50052198 NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C20H31N6O8P/c21-12-8-11(4-5-15(12)34-35(31,32)33)9-13(22)18(29)26-20(6-2-1-3-7-20)19(30)25-14(17(24)28)10-16(23)27/h4-5,8,13-14H,1-3,6-7,9-10,21-22H2,(H2,23,27)(H2,24,28)(H,25,30)(H,26,29)(H2,31,32,33) YJYFCZXVXPEVDA-UHFFFAOYSA-N 50064333 CHEMBL49860::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 1 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064333&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44293722 103959385 CHEMBL49860 ZINC29462766 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50056545 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)c(c1)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O12/c39-30(44)20-28(32(47)40-17-7-11-24-10-6-9-23-8-2-3-12-25(23)24)42-37(54)38(15-4-1-5-16-38)43-33(48)27(41-34(49)36(52)53)19-22-13-14-29(55-21-31(45)46)26(18-22)35(50)51/h2-3,6,8-10,12-14,18,27-28H,1,4-5,7,11,15-17,19-21H2,(H2,39,44)(H,40,47)(H,41,49)(H,42,54)(H,43,48)(H,45,46)(H,50,51)(H,52,53)/t27-,28-/m0/s1 KXQNRHHJZUCNQZ-NSOVKSMOSA-N 50072868 5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-2-carboxymethoxy-benzoic acid::CHEMBL332671 Growth factor receptor-bound protein 2 Homo sapiens 1300 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072868&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10417671 103966459 CHEMBL332671 ZINC95611184 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50056546 CC(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44F2N5O8P/c1-23(44)41-29(21-24-14-16-27(17-15-24)36(37,38)52(49,50)51)33(47)43-35(18-5-2-6-19-35)34(48)42-30(22-31(39)45)32(46)40-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,48)(H,43,47)(H2,49,50,51)/t29-,30-/m0/s1 MIWDBKYDYWIMMF-KYJUHHDHSA-N 50072864 CHEMBL115699::{[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-difluoro-methyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 500 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072864&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10795115 103966455 CHEMBL115699 ZINC95546520 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50056547 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H46N5O8P/c1-24(42)39-30(21-25-14-16-26(17-15-25)23-50(47,48)49)34(45)41-36(18-5-2-6-19-36)35(46)40-31(22-32(37)43)33(44)38-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,37,43)(H,38,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t30-,31-/m0/s1 MNFGRMAJNGDXMU-CONSDPRKSA-N 50072861 CHEMBL19417::[(S)-4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 80 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072861&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10699955 103966452 CHEMBL19417 ZINC28225403 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50053892 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCCCc1cccc2ccccc12)C(O)=O InChI=1S/C36H45N4O11P/c1-4-5-15-31(39-34(44)30(37)21-25-16-18-28(19-17-25)51-52(48,49-23(2)41)50-24(3)42)35(45)40-32(36(46)47)22-33(43)38-20-9-13-27-12-8-11-26-10-6-7-14-29(26)27/h6-8,10-12,14,16-19,30-32H,4-5,9,13,15,20-22,37H2,1-3H3,(H,38,43)(H,39,44)(H,40,45)(H,46,47) QXNYFHSLIJYAAE-UHFFFAOYSA-N 50066509 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-(3-naphthalen-1-yl-propyl)-succinamic acid::CHEMBL430699 Growth factor receptor-bound protein 2 Homo sapiens 580 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066509&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343322 103961135 CHEMBL430699 C00316 ZINC37099213 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50053893 CC(=O)OP(=O)(OC(C)=O)Oc1ccc(CC(N)C(=O)CC(=O)CCCCCCNC(CC(=O)NCCCc2cccc3ccccc23)C(O)=O)cc1 InChI=1S/C38H48N3O11P/c1-26(42)50-53(49,51-27(2)43)52-32-19-17-28(18-20-32)23-34(39)36(45)24-31(44)15-5-3-4-8-21-40-35(38(47)48)25-37(46)41-22-10-14-30-13-9-12-29-11-6-7-16-33(29)30/h6-7,9,11-13,16-20,34-35,40H,3-5,8,10,14-15,21-25,39H2,1-2H3,(H,41,46)(H,47,48) WHNDKGHJSGTRIX-UHFFFAOYSA-N 50066510 2-{10-Amino-11-[4-(diacetoxy-phosphoryloxy)-phenyl]-7,9-dioxo-undecylamino}-N-(3-naphthalen-1-yl-propyl)-succinamic acid::CHEMBL325621 Growth factor receptor-bound protein 2 Homo sapiens 47 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066510&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343296 103961136 CHEMBL325621 ZINC95542293 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50065997 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O9/c38-30(43)22-29(32(46)39-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-24(16-14-23)21-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 XYXSUXVWOJXCIE-VMPREFPWSA-N 50085877 CHEMBL355066::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 600 ChEMBL 10.1021/jm050154v 10.7270/Q2513XRP 16078854 Kang, SU; Worthy, KM; Bindu, LK; Zhang, M; Yang, D; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085877&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10032662 103985287 CHEMBL355066 C03768 ZINC27992388 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102175 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C24H37N6O11P/c1-3-12(2)20(24(37)28-16(21(27)34)11-18(26)31)30-23(36)17(29-22(35)15(25)8-9-19(32)33)10-13-4-6-14(7-5-13)41-42(38,39)40/h4-7,12,15-17,20H,3,8-11,25H2,1-2H3,(H2,26,31)(H2,27,34)(H,28,37)(H,29,35)(H,30,36)(H,32,33)(H2,38,39,40)/t12-,15-,16-,17-,20-/m0/s1 QRMJQIXNAMWZGT-DTDKCHBMSA-N 50060520 (S)-4-Amino-4-[(S)-1-[(1S,2S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-butyric acid::CHEMBL332374 Growth factor receptor-bound protein 2 Homo sapiens 7900 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060520&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10508058 103956266 CHEMBL332374 C01167 ZINC27104871 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102176 CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C19H30N5O8P/c1-3-10(2)16(19(28)23-14(17(22)26)9-15(21)25)24-18(27)13(20)8-11-4-6-12(7-5-11)32-33(29,30)31/h4-7,10,13-14,16H,3,8-9,20H2,1-2H3,(H2,21,25)(H2,22,26)(H,23,28)(H,24,27)(H2,29,30,31)/t10-,13-,14-,16-/m0/s1 YKDWUTQPXKYIRW-CFMVVWHZSA-N 50060521 CHEMBL118200::Phosphoric acid mono-(4-{(S)-2-amino-2-[(1S,2S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 56900.0 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060521&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10601009 103956267 CHEMBL118200 ZINC13606447 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102177 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C27H37N6O10P/c1-3-15(2)23(26(37)31-20(24(30)35)13-22(29)34)33-25(36)21(12-16-7-9-19(10-8-16)43-44(39,40)41)32-27(38)42-14-17-5-4-6-18(28)11-17/h4-11,15,20-21,23H,3,12-14,28H2,1-2H3,(H2,29,34)(H2,30,35)(H,31,37)(H,32,38)(H,33,36)(H2,39,40,41)/t15-,20-,21-,23-/m0/s1 NIOCFHRLKNWSBD-RJCMWMPSSA-N 50060522 CHEMBL327037::[(S)-1-[(1S,2S)-1-((S)-1,2-Dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 65 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060522&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10579932 103956268 CHEMBL327037 C01167 ZINC27108139 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102178 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C21H32N5O9P/c1-4-11(2)18(21(31)25-15(19(23)29)10-17(22)28)26-20(30)16(24-12(3)27)9-13-5-7-14(8-6-13)35-36(32,33)34/h5-8,11,15-16,18H,4,9-10H2,1-3H3,(H2,22,28)(H2,23,29)(H,24,27)(H,25,31)(H,26,30)(H2,32,33,34)/t11-,15-,16-,18-/m0/s1 OWGDZTBZWQPSHR-SLBDDTMCSA-N 50060523 CHEMBL118574::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(1S,2S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 8640.0 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060523&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10816029 103956269 CHEMBL118574 C01167 ZINC27108130 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102179 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C27H36N5O10P/c1-3-16(2)23(26(36)30-20(24(29)34)14-22(28)33)32-25(35)21(31-27(37)41-15-18-7-5-4-6-8-18)13-17-9-11-19(12-10-17)42-43(38,39)40/h4-12,16,20-21,23H,3,13-15H2,1-2H3,(H2,28,33)(H2,29,34)(H,30,36)(H,31,37)(H,32,35)(H2,38,39,40)/t16-,20-,21-,23-/m0/s1 PHUSUERYUUQVRN-IWZNJAMVSA-N 50060524 CHEMBL420319::[(S)-1-[(1S,2S)-1-((S)-1,2-Dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 6350 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060524&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10603930 103956270 CHEMBL420319 C01167 ZINC27106909 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50102180 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)c1ccccc1N)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C31H42N7O12P/c1-3-16(2)26(31(46)36-22(27(34)42)15-24(33)39)38-30(45)23(14-17-8-10-18(11-9-17)50-51(47,48)49)37-29(44)21(12-13-25(40)41)35-28(43)19-6-4-5-7-20(19)32/h4-11,16,21-23,26H,3,12-15,32H2,1-2H3,(H2,33,39)(H2,34,42)(H,35,43)(H,36,46)(H,37,44)(H,38,45)(H,40,41)(H2,47,48,49)/t16-,21-,22-,23-,26-/m0/s1 XMPAXFKPWIBALJ-JAEJYZBISA-N 50060525 (S)-4-(2-Amino-benzoylamino)-4-[(S)-1-[(1S,2S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-butyric acid::CHEMBL331438 Growth factor receptor-bound protein 2 Homo sapiens 22 ChEMBL 10.1021/jm9702185 10.7270/Q2X06650 9357522 Furet, P; Gay, B; Garcia-Echeverria, C; Rahuel, J; Fretz, H; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060525&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10556926 103956271 CHEMBL331438 C01167 ZINC27102711 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110086 NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C20H31N6O8P/c21-12-8-11(4-5-15(12)34-35(31,32)33)9-13(22)18(29)26-20(6-2-1-3-7-20)19(30)25-14(17(24)28)10-16(23)27/h4-5,8,13-14H,1-3,6-7,9-10,21-22H2,(H2,23,27)(H2,24,28)(H,25,30)(H,26,29)(H2,31,32,33) YJYFCZXVXPEVDA-UHFFFAOYSA-N 50064333 CHEMBL49860::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 0.004 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064333&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44293722 103959385 CHEMBL49860 ZINC29462766 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110087 CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C19H31N6O8P/c1-3-9(2)16(19(29)24-13(17(23)27)8-15(22)26)25-18(28)12(21)7-10-4-5-14(11(20)6-10)33-34(30,31)32/h4-6,9,12-13,16H,3,7-8,20-21H2,1-2H3,(H2,22,26)(H2,23,27)(H,24,29)(H,25,28)(H2,30,31,32)/t9-,12-,13-,16-/m0/s1 NJEVXGGPQNULLV-BOKHUEBRSA-N 50064334 CHEMBL2372812::Phosphoric acid mono-(2-amino-4-{2-amino-2-[(1S,2R)-1-(1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 65 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064334&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73350305 103959386 CHEMBL2372812 ZINC29462108 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110091 NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(Cc2ccccc2C1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C23H29N6O8P/c24-15-7-12(5-6-18(15)37-38(34,35)36)8-16(25)21(32)29-23(10-13-3-1-2-4-14(13)11-23)22(33)28-17(20(27)31)9-19(26)30/h1-7,16-17H,8-11,24-25H2,(H2,26,30)(H2,27,31)(H,28,33)(H,29,32)(H2,34,35,36) NMBMLNUOAJRNQE-UHFFFAOYSA-N 50064335 CHEMBL49752::Phosphoric acid mono-(2-amino-4-{2-amino-2-[2-(1,2-dicarbamoyl-ethylcarbamoyl)-indan-2-ylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 140 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064335&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44293701 103959387 CHEMBL49752 ZINC29462837 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110092 N[C@@H](Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C19H29N6O8P/c20-11-7-10(3-4-14(11)33-34(30,31)32)8-12(21)17(28)25-19(5-1-2-6-19)18(29)24-13(16(23)27)9-15(22)26/h3-4,7,12-13H,1-2,5-6,8-9,20-21H2,(H2,22,26)(H2,23,27)(H,24,29)(H,25,28)(H2,30,31,32)/t12-,13-/m0/s1 JSBGEXFUYQLMBR-STQMWFEESA-N 50064336 CHEMBL2372811::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclopentylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 23 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064336&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73345722 103959388 CHEMBL2372811 ZINC29467725 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110093 N[C@@H](Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C17H25N6O8P/c18-9-5-8(1-2-12(9)31-32(28,29)30)6-10(19)15(26)23-17(3-4-17)16(27)22-11(14(21)25)7-13(20)24/h1-2,5,10-11H,3-4,6-7,18-19H2,(H2,20,24)(H2,21,25)(H,22,27)(H,23,26)(H2,28,29,30)/t10-,11-/m0/s1 QXVADDZFHSYLJE-QWRGUYRKSA-N 50064337 CHEMBL2372814::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclopropylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 124 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064337&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73350307 103959389 CHEMBL2372814 ZINC29466216 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50110096 CC(C)(NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C17H27N6O8P/c1-17(2,16(27)22-11(14(21)25)7-13(20)24)23-15(26)10(19)6-8-3-4-12(9(18)5-8)31-32(28,29)30/h3-5,10-11H,6-7,18-19H2,1-2H3,(H2,20,24)(H2,21,25)(H,22,27)(H,23,26)(H2,28,29,30)/t10-,11-/m0/s1 DXOHGMAWXWDFST-QWRGUYRKSA-N 50064338 CHEMBL2372813::Phosphoric acid mono-(2-amino-4-{2-amino-2-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-1-methyl-ethylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 206 ChEMBL 10.1021/jm970856n 10.7270/Q2M32TWK 9599224 Garcia-Echeverria, C; Furet, P; Gay, B; Fretz, H; Rahuel, J; Schoepfer, J; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064338&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73350306 103959390 CHEMBL2372813 ZINC29462118 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114518 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(N)=O)C(O)=O InChI=1S/C23H33N4O11P/c1-4-5-6-18(22(32)27-19(23(33)34)12-20(25)30)26-21(31)17(24)11-15-7-9-16(10-8-15)38-39(35,36-13(2)28)37-14(3)29/h7-10,17-19H,4-6,11-12,24H2,1-3H3,(H2,25,30)(H,26,31)(H,27,32)(H,33,34) ZGEDFCPSZQNBDC-UHFFFAOYSA-N 50066508 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-succinamic acid::CHEMBL116726 Growth factor receptor-bound protein 2 Homo sapiens 8900 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066508&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343379 103961134 CHEMBL116726 C00316 ZINC36352041 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114521 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCCCc1cccc2ccccc12)C(O)=O InChI=1S/C36H45N4O11P/c1-4-5-15-31(39-34(44)30(37)21-25-16-18-28(19-17-25)51-52(48,49-23(2)41)50-24(3)42)35(45)40-32(36(46)47)22-33(43)38-20-9-13-27-12-8-11-26-10-6-7-14-29(26)27/h6-8,10-12,14,16-19,30-32H,4-5,9,13,15,20-22,37H2,1-3H3,(H,38,43)(H,39,44)(H,40,45)(H,46,47) QXNYFHSLIJYAAE-UHFFFAOYSA-N 50066509 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-(3-naphthalen-1-yl-propyl)-succinamic acid::CHEMBL430699 Growth factor receptor-bound protein 2 Homo sapiens 330 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066509&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343322 103961135 CHEMBL430699 C00316 ZINC37099213 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114523 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCC(C)C)C(O)=O InChI=1S/C27H41N4O11P/c1-6-7-8-22(26(36)31-23(27(37)38)14-24(34)29-15-16(2)3)30-25(35)21(28)13-19-9-11-20(12-10-19)42-43(39,40-17(4)32)41-18(5)33/h9-12,16,21-23H,6-8,13-15,28H2,1-5H3,(H,29,34)(H,30,35)(H,31,36)(H,37,38) DXRUVHDCEDGTEZ-UHFFFAOYSA-N 50066511 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-isobutyl-succinamic acid::CHEMBL116495 Growth factor receptor-bound protein 2 Homo sapiens 3200 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066511&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343347 103961137 CHEMBL116495 C00316 ZINC36352037 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114524 CCCCC(CC)CNC(=O)CC(NC(=O)C(CCCC)NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(O)=O InChI=1S/C31H49N4O11P/c1-6-9-11-22(8-3)19-33-28(38)18-27(31(41)42)35-30(40)26(12-10-7-2)34-29(39)25(32)17-23-13-15-24(16-14-23)46-47(43,44-20(4)36)45-21(5)37/h13-16,22,25-27H,6-12,17-19,32H2,1-5H3,(H,33,38)(H,34,39)(H,35,40)(H,41,42) VLPCGCZDGREOFJ-UHFFFAOYSA-N 50066512 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-(2-ethyl-hexyl)-succinamic acid::CHEMBL113789 Growth factor receptor-bound protein 2 Homo sapiens 1600 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066512&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343380 103961138 CHEMBL113789 C00316 ZINC37099209 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114525 CC(=O)OP(=O)(OC(C)=O)Oc1ccc(CC(N)C(=O)CC(=O)CCCCCCNC(CC(=O)NCCCc2cccc3ccccc23)C(O)=O)cc1 InChI=1S/C38H48N3O11P/c1-26(42)50-53(49,51-27(2)43)52-32-19-17-28(18-20-32)23-34(39)36(45)24-31(44)15-5-3-4-8-21-40-35(38(47)48)25-37(46)41-22-10-14-30-13-9-12-29-11-6-7-16-33(29)30/h6-7,9,11-13,16-20,34-35,40H,3-5,8,10,14-15,21-25,39H2,1-2H3,(H,41,46)(H,47,48) WHNDKGHJSGTRIX-UHFFFAOYSA-N 50066510 2-{10-Amino-11-[4-(diacetoxy-phosphoryloxy)-phenyl]-7,9-dioxo-undecylamino}-N-(3-naphthalen-1-yl-propyl)-succinamic acid::CHEMBL325621 Growth factor receptor-bound protein 2 Homo sapiens 64 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066510&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343296 103961136 CHEMBL325621 ZINC95542293 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114527 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCCCc1ccc(Cl)cc1Cl)C(O)=O InChI=1S/C32H41Cl2N4O11P/c1-4-5-8-27(31(43)38-28(32(44)45)18-29(41)36-15-6-7-22-11-12-23(33)17-25(22)34)37-30(42)26(35)16-21-9-13-24(14-10-21)49-50(46,47-19(2)39)48-20(3)40/h9-14,17,26-28H,4-8,15-16,18,35H2,1-3H3,(H,36,41)(H,37,42)(H,38,43)(H,44,45) AJNNCSNHKWAFNJ-UHFFFAOYSA-N 50066513 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-[3-(2,4-dichloro-phenyl)-propyl]-succinamic acid::CHEMBL326112 Growth factor receptor-bound protein 2 Homo sapiens 1500 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066513&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343295 103961139 CHEMBL326112 C00316 ZINC95610814 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114528 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCCC(C)C)C(O)=O InChI=1S/C28H43N4O11P/c1-6-7-8-23(27(37)32-24(28(38)39)16-25(35)30-14-13-17(2)3)31-26(36)22(29)15-20-9-11-21(12-10-20)43-44(40,41-18(4)33)42-19(5)34/h9-12,17,22-24H,6-8,13-16,29H2,1-5H3,(H,30,35)(H,31,36)(H,32,37)(H,38,39) HVFJPYOLLFQOSC-UHFFFAOYSA-N 50066514 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-(3-methyl-butyl)-succinamic acid::CHEMBL117139 Growth factor receptor-bound protein 2 Homo sapiens 3100 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066514&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343368 103961140 CHEMBL117139 C00316 ZINC36352039 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50114529 CCCCC(NC(=O)C(N)Cc1ccc(OP(=O)(OC(C)=O)OC(C)=O)cc1)C(=O)NC(CC(=O)NCCCc1ccccc1)C(O)=O InChI=1S/C32H43N4O11P/c1-4-5-13-27(31(41)36-28(32(42)43)20-29(39)34-18-9-12-23-10-7-6-8-11-23)35-30(40)26(33)19-24-14-16-25(17-15-24)47-48(44,45-21(2)37)46-22(3)38/h6-8,10-11,14-17,26-28H,4-5,9,12-13,18-20,33H2,1-3H3,(H,34,39)(H,35,40)(H,36,41)(H,42,43) HLUBEYLDWMSKMS-UHFFFAOYSA-N 50066515 2-(2-{2-Amino-3-[4-(diacetoxy-phosphoryloxy)-phenyl]-propionylamino}-hexanoylamino)-N-(3-phenyl-propyl)-succinamic acid::CHEMBL324094 Growth factor receptor-bound protein 2 Homo sapiens 2300 ChEMBL 10.1021/jm980159a 10.7270/Q23R0S0N 9719597 Furet, P; Gay, B; Caravatti, G; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J; Fretz, H Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066515&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44343346 103961141 CHEMBL324094 C00316 ZINC37099211 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126156 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H46N5O8P/c1-24(42)39-30(21-25-14-16-26(17-15-25)23-50(47,48)49)34(45)41-36(18-5-2-6-19-36)35(46)40-31(22-32(37)43)33(44)38-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,37,43)(H,38,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t30-,31-/m0/s1 MNFGRMAJNGDXMU-CONSDPRKSA-N 50072861 CHEMBL19417::[(S)-4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 80 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072861&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10699955 103966452 CHEMBL19417 ZINC28225403 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126157 CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H43N5O6/c1-23(41)38-29(21-24-14-16-27(42)17-15-24)33(45)40-35(18-5-2-6-19-35)34(46)39-30(22-31(36)43)32(44)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30,42H,2,5-6,8,12,18-22H2,1H3,(H2,36,43)(H,37,44)(H,38,41)(H,39,46)(H,40,45)/t29-,30-/m0/s1 WOSWFZJSUXFRDV-KYJUHHDHSA-N 50072863 (S)-2-({1-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-cyclohexanecarbonyl}-amino)-N*1*-(3-naphthalen-1-yl-propyl)-succinamide::CHEMBL119360 Growth factor receptor-bound protein 2 Homo sapiens >50000 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072863&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10627780 103966454 CHEMBL119360 ZINC27106177 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126158 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30-/m0/s1 ATTZUIWVKJIUFV-KYJUHHDHSA-N 50072862 CHEMBL117807::Phosphoric acid mono-[4-((S)-2-acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester::Phosphoric acid mono-[4-(2-acetylamino-2-{(S)-1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 70.0 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072862&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987342 103966453 CHEMBL117807 C01167 ZINC27102270 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126160 CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(N)=O)NC(C)=O InChI=1S/C27H40N7O11PS2/c1-4-13(2)22-27(41)32-18(10-21(28)36)24(38)33-19(23(29)37)11-47-48-12-20(30-14(3)35)26(40)31-17(25(39)34-22)9-15-5-7-16(8-6-15)45-46(42,43)44/h5-8,13,17-20,22H,4,9-12H2,1-3H3,(H2,28,36)(H2,29,37)(H,30,35)(H,31,40)(H,32,41)(H,33,38)(H,34,39)(H2,42,43,44)/t13-,17-,18-,19-,20-,22-/m0/s1 KGFRJOXTDUHEFL-SDFAOIKNSA-N 50072866 CHEMBL2370501::Phosphoric acid mono-[4-((4R,7S,10S,13S,16R)-16-acetylamino-10-sec-butyl-4-carbamoyl-7-carbamoylmethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-13-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 370 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072866&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73348501 103966457 CHEMBL2370501 ZINC27100561 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126161 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 500 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126162 CC(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44F2N5O8P/c1-23(44)41-29(21-24-14-16-27(17-15-24)36(37,38)52(49,50)51)33(47)43-35(18-5-2-6-19-35)34(48)42-30(22-31(39)45)32(46)40-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,48)(H,43,47)(H2,49,50,51)/t29-,30-/m0/s1 MIWDBKYDYWIMMF-KYJUHHDHSA-N 50072864 CHEMBL115699::{[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-difluoro-methyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 80 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072864&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10795115 103966455 CHEMBL115699 ZINC95546520 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126163 CC(=O)N[C@@H](Cc1ccc(OCC(O)=O)c(c1)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H45N5O10/c1-23(44)41-29(20-24-14-15-31(53-22-33(46)47)28(19-24)36(50)51)35(49)43-38(16-5-2-6-17-38)37(52)42-30(21-32(39)45)34(48)40-18-8-12-26-11-7-10-25-9-3-4-13-27(25)26/h3-4,7,9-11,13-15,19,29-30H,2,5-6,8,12,16-18,20-22H2,1H3,(H2,39,45)(H,40,48)(H,41,44)(H,42,52)(H,43,49)(H,46,47)(H,50,51)/t29-,30-/m0/s1 VWXWFRWMYFXHQA-KYJUHHDHSA-N 50072867 5-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-2-carboxymethoxy-benzoic acid::CHEMBL324310 Growth factor receptor-bound protein 2 Homo sapiens 6700 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10771240 103966458 CHEMBL324310 ZINC27101185 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126166 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)c(c1)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O12/c39-30(44)20-28(32(47)40-17-7-11-24-10-6-9-23-8-2-3-12-25(23)24)42-37(54)38(15-4-1-5-16-38)43-33(48)27(41-34(49)36(52)53)19-22-13-14-29(55-21-31(45)46)26(18-22)35(50)51/h2-3,6,8-10,12-14,18,27-28H,1,4-5,7,11,15-17,19-21H2,(H2,39,44)(H,40,47)(H,41,49)(H,42,54)(H,43,48)(H,45,46)(H,50,51)(H,52,53)/t27-,28-/m0/s1 KXQNRHHJZUCNQZ-NSOVKSMOSA-N 50072868 5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-2-carboxymethoxy-benzoic acid::CHEMBL332671 Growth factor receptor-bound protein 2 Homo sapiens 500 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072868&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10417671 103966459 CHEMBL332671 ZINC95611184 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126167 CC(=O)N[C@@H](Cc1ccc(OCC(O)=O)c(OCC(O)=O)c1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C39H47N5O11/c1-24(45)42-29(19-25-14-15-31(54-22-34(47)48)32(20-25)55-23-35(49)50)37(52)44-39(16-5-2-6-17-39)38(53)43-30(21-33(40)46)36(51)41-18-8-12-27-11-7-10-26-9-3-4-13-28(26)27/h3-4,7,9-11,13-15,20,29-30H,2,5-6,8,12,16-19,21-23H2,1H3,(H2,40,46)(H,41,51)(H,42,45)(H,43,53)(H,44,52)(H,47,48)(H,49,50)/t29-,30-/m0/s1 HVGSJASWJDDARC-KYJUHHDHSA-N 50072870 CHEMBL332124::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-2-carboxymethoxy-phenoxy]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens >100000 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072870&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10818927 103966461 CHEMBL332124 ZINC95611070 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126168 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1c(O)ccc2ccccc12 InChI=1S/C35H44N5O10P/c1-22(41)38-28(20-23-11-14-25(15-12-23)50-51(47,48)49)33(45)40-35(17-5-2-6-18-35)34(46)39-29(21-31(36)43)32(44)37-19-7-10-27-26-9-4-3-8-24(26)13-16-30(27)42/h3-4,8-9,11-16,28-29,42H,2,5-7,10,17-21H2,1H3,(H2,36,43)(H,37,44)(H,38,41)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 CXODOSYKGYEMEC-VMPREFPWSA-N 50072869 CHEMBL331463::Phosphoric acid mono-{4-[(S)-2-acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(2-hydroxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-phenyl} ester Growth factor receptor-bound protein 2 Homo sapiens 11 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072869&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344470 103966460 CHEMBL331463 C01167 ZINC27105548 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124711 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(N)=O)c1cccc(NC(N)=O)c1 InChI=1S/C22H28N5O8P/c1-13(28)25-19(11-14-5-7-17(8-6-14)35-36(32,33)34)21(30)27-18(9-10-20(23)29)15-3-2-4-16(12-15)26-22(24)31/h2-8,12,18-19H,9-11H2,1H3,(H2,23,29)(H,25,28)(H,27,30)(H3,24,26,31)(H2,32,33,34)/t18-,19-/m0/s1 QDOUVRAKYRKUNX-OALUTQOASA-N 50072183 CHEMBL319289::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-3-carbamoyl-1-(3-ureido-phenyl)-propylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 6500 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072183&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10075384 103965835 CHEMBL319289 C01167 ZINC26719140 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124712 CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C20H30N5O9P/c1-10(2)17(20(30)24-14(18(22)28)9-16(21)27)25-19(29)15(23-11(3)26)8-12-4-6-13(7-5-12)34-35(31,32)33/h4-7,10,14-15,17H,8-9H2,1-3H3,(H2,21,27)(H2,22,28)(H,23,26)(H,24,30)(H,25,29)(H2,31,32,33)/t14-,15-,17-/m0/s1 GSJUDVVVSUJCMF-ZOBUZTSGSA-N 50072184 CHEMBL292567::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-propylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 4320.0 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072184&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44302277 103965836 CHEMBL292567 C01167 ZINC26156308 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124713 CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1cccc(NC(N)=O)c1 InChI=1S/C22H29N4O7P/c1-13(2)20(16-5-4-6-17(12-16)25-22(23)29)26-21(28)19(24-14(3)27)11-15-7-9-18(10-8-15)33-34(30,31)32/h4-10,12-13,19-20H,11H2,1-3H3,(H,24,27)(H,26,28)(H3,23,25,29)(H2,30,31,32)/t19-,20-/m0/s1 RAVAJHOVWMQVFP-PMACEKPBSA-N 50072185 CHEMBL95550::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-2-methyl-1-(3-ureido-phenyl)-propylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 6190 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072185&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10435751 103965837 CHEMBL95550 C01167 ZINC26725526 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124714 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C17H24N5O9P/c1-9(23)21-13(6-10-2-4-11(5-3-10)31-32(28,29)30)17(27)20-8-15(25)22-12(16(19)26)7-14(18)24/h2-5,12-13H,6-8H2,1H3,(H2,18,24)(H2,19,26)(H,20,27)(H,21,23)(H,22,25)(H2,28,29,30)/t12-,13-/m0/s1 VEXZKKOEFKAIQW-STQMWFEESA-N 50072186 CHEMBL61047::Phosphoric acid mono-[4-((S)-2-acetylamino-2-{[((S)-1,2-dicarbamoyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 67000 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072186&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44302560 103965838 CHEMBL61047 C01167 ZINC26158594 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124715 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C20H29N6O10P/c1-10(27)24-15(8-11-2-4-12(5-3-11)36-37(33,34)35)20(32)25-13(6-7-16(21)28)19(31)26-14(18(23)30)9-17(22)29/h2-5,13-15H,6-9H2,1H3,(H2,21,28)(H2,22,29)(H2,23,30)(H,24,27)(H,25,32)(H,26,31)(H2,33,34,35)/t13-,14-,15-/m0/s1 JFCWFJBJUSKYOC-KKUMJFAQSA-N 50072187 CHEMBL98515::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-3-carbamoyl-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-propylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 5440 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072187&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44329161 103965839 CHEMBL98515 C01167 ZINC26721483 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50124716 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCc1cccc(NC(N)=O)c1 InChI=1S/C19H23N4O7P/c1-12(24)22-17(10-13-5-7-16(8-6-13)30-31(27,28)29)18(25)21-11-14-3-2-4-15(9-14)23-19(20)26/h2-9,17H,10-11H2,1H3,(H,21,25)(H,22,24)(H3,20,23,26)(H2,27,28,29)/t17-/m0/s1 VJCSXAUENNDTNJ-KRWDZBQOSA-N 50072188 CHEMBL316834::Phosphoric acid mono-{4-[(S)-2-acetylamino-2-(3-ureido-benzylcarbamoyl)-ethyl]-phenyl} ester Growth factor receptor-bound protein 2 Homo sapiens 48660 ChEMBL 10.1016/s0960-894x(98)00513-7 10.7270/Q2T72GKN 9873638 Schoepfer, J; Gay, B; Caravatti, G; Garcia-Echeverria, C; Fretz, H; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072188&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44329275 103965840 CHEMBL316834 C01167 ZINC26717391 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50126155 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C44H66N11O21P/c1-19(2)34(41(68)48-24(44(71)72)11-12-30(46)57)54-38(65)26(16-31(47)58)50-42(69)35(20(3)4)53-37(64)25(14-21-7-9-22(10-8-21)76-77(73,74)75)49-39(66)28(18-56)52-40(67)29-6-5-13-55(29)43(70)27(17-33(61)62)51-36(63)23(45)15-32(59)60/h7-10,19-20,23-29,34-35,56H,5-6,11-18,45H2,1-4H3,(H2,46,57)(H2,47,58)(H,48,68)(H,49,66)(H,50,69)(H,51,63)(H,52,67)(H,53,64)(H,54,65)(H,59,60)(H,61,62)(H,71,72)(H2,73,74,75)/t23-,24-,25-,26-,27-,28-,29-,34-,35-/m0/s1 VXWBXLGFPCBMJZ-KUMVYFBMSA-N 50072860 Asp-Asp-Pro-Ser-pTyr-Val-Asn-Val-Gln::CHEMBL412230 Growth factor receptor-bound protein 2 Homo sapiens 1300 ChEMBL 10.1021/jm980388x 10.7270/Q2FT8K6P 9888830 Yao, ZJ; King, CR; Cao, T; Kelley, J; Milne, GW; Voigt, JH; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072860&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344471 103966451 CHEMBL412230 C02716 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129583 CC(C)[C@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(C)C InChI=1S/C30H44N7O11P/c1-15(2)24-29(43)34-20(13-22(31)38)27(41)36-25(16(3)4)30(44)37-11-5-6-21(37)28(42)32-14-23(39)33-19(26(40)35-24)12-17-7-9-18(10-8-17)48-49(45,46)47/h7-10,15-16,19-21,24-25H,5-6,11-14H2,1-4H3,(H2,31,38)(H,32,42)(H,33,39)(H,34,43)(H,35,40)(H,36,41)(H2,45,46,47)/t19-,20-,21-,24+,25+/m0/s1 LEIBQLDKRFRHEP-PMDWNULLSA-N 50074703 CHEMBL172299::Phosphoric acid mono-[4-((5R,8S,11R,14S,19aS)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,19-hexaoxo-octadecahydro-3a,6,9,12,15,18-hexaaza-cyclopentacyclooctadecen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 520 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074703&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44385824 103967895 CHEMBL172299 ZINC28015835 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129585 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)NC(C)=S InChI=1S/C36H55N8O11PS/c1-19(2)29-35(50)41-26(18-28(37)45)33(48)43-30(20(3)4)36(51)44-16-8-10-27(44)34(49)38-15-7-6-9-24(39-21(5)57)31(46)40-25(32(47)42-29)17-22-11-13-23(14-12-22)55-56(52,53)54/h11-14,19-20,24-27,29-30H,6-10,15-18H2,1-5H3,(H2,37,45)(H,38,49)(H,39,57)(H,40,46)(H,41,50)(H,42,47)(H,43,48)(H2,52,53,54)/t24-,25-,26-,27-,29+,30+/m1/s1 HWIHFQSDJBSOLW-WOMNCXHOSA-N 50074706 CHEMBL366543::Phosphoric acid mono-[4-((5S,8R,11S,14R,17R,23aR)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,23-hexaoxo-17-thioacetylamino-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 110 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074706&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44385823 103967898 CHEMBL366543 ZINC95612487 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129586 CC(C)C[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)NC(C)=O InChI=1S/C37H57N8O12P/c1-20(2)17-26-33(49)43-28(19-30(38)47)35(51)44-31(21(3)4)37(53)45-16-8-10-29(45)36(52)39-15-7-6-9-25(40-22(5)46)32(48)42-27(34(50)41-26)18-23-11-13-24(14-12-23)57-58(54,55)56/h11-14,20-21,25-29,31H,6-10,15-19H2,1-5H3,(H2,38,47)(H,39,52)(H,40,46)(H,41,50)(H,42,48)(H,43,49)(H,44,51)(H2,54,55,56)/t25-,26-,27+,28+,29+,31-/m0/s1 KCSWZWCIACSYPO-BXURBOKHSA-N 50074708 CHEMBL177616::Phosphoric acid mono-[4-((5S,8R,11S,14R,17S,23aR)-17-acetylamino-8-carbamoylmethyl-11-isobutyl-5-isopropyl-4,7,10,13,16,23-hexaoxo-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 1340 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074708&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386411 103967900 CHEMBL177616 ZINC95606461 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129588 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)C(O)=O)NC(C)=O InChI=1S/C36H53N8O14PS2/c1-17(2)28-34(51)40-23(14-27(37)46)31(48)43-29(18(3)4)35(52)44-12-6-7-26(44)33(50)41-25(36(53)54)16-61-60-15-24(38-19(5)45)32(49)39-22(30(47)42-28)13-20-8-10-21(11-9-20)58-59(55,56)57/h8-11,17-18,22-26,28-29H,6-7,12-16H2,1-5H3,(H2,37,46)(H,38,45)(H,39,49)(H,40,51)(H,41,50)(H,42,47)(H,43,48)(H,53,54)(H2,55,56,57)/t22-,23-,24+,25+,26-,28+,29+/m1/s1 CTJKPNJIZJWNRA-YBYLUTCOSA-N 50074709 (5S,8R,11S,14R,17R,22R,24aR)-17-Acetylamino-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,24-hexaoxo-14-(4-phosphonooxy-benzyl)-docosahydro-19,20-dithia-3a,6,9,12,15,23-hexaaza-cyclopentacyclotricosene-22-carboxylic acid::CHEMBL367440 Growth factor receptor-bound protein 2 Homo sapiens 630 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074709&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387059 103967901 CHEMBL367440 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129590 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H](CC(N)=O)NC1=O)NC(C)=O InChI=1S/C40H61N8O12P/c1-23(2)34-39(55)45-30(22-33(41)50)36(52)46-31(21-25-10-5-4-6-11-25)40(56)48-19-9-13-32(48)38(54)42-18-8-7-12-28(43-24(3)49)35(51)44-29(37(53)47-34)20-26-14-16-27(17-15-26)60-61(57,58)59/h14-17,23,25,28-32,34H,4-13,18-22H2,1-3H3,(H2,41,50)(H,42,54)(H,43,49)(H,44,51)(H,45,55)(H,46,52)(H,47,53)(H2,57,58,59)/t28-,29+,30+,31-,32+,34-/m0/s1 WMTSEKHBXFDPLG-KJVBWLMSSA-N 50074711 CHEMBL355759::Phosphoric acid mono-[4-((5S,8R,11S,14R,17S,23aR)-17-acetylamino-8-carbamoylmethyl-5-cyclohexylmethyl-11-isopropyl-4,7,10,13,16,23-hexaoxo-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 110 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074711&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44385517 103967903 CHEMBL355759 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129592 CC(C)[C@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CCCCCCNC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(C)C InChI=1S/C35H54N7O11P/c1-20(2)29-34(48)39-25(19-27(36)43)32(46)41-30(21(3)4)35(49)42-17-9-10-26(42)33(47)37-16-8-6-5-7-11-28(44)38-24(31(45)40-29)18-22-12-14-23(15-13-22)53-54(50,51)52/h12-15,20-21,24-26,29-30H,5-11,16-19H2,1-4H3,(H2,36,43)(H,37,47)(H,38,44)(H,39,48)(H,40,45)(H,41,46)(H2,50,51,52)/t24-,25-,26-,29+,30+/m0/s1 HWLWTXLSPMBBBR-SBROXDMYSA-N 50074712 CHEMBL177372::Phosphoric acid mono-[4-((5R,8S,11R,14S,24aS)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,24-hexaoxo-tetracosahydro-3a,6,9,12,15,23-hexaaza-cyclopentacyclotricosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 600 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074712&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386888 103967904 CHEMBL177372 ZINC95606459 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129593 CCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)CC)C(C)C)C(C)C InChI=1S/C35H56N7O11P/c1-7-9-16-37-33(47)26-11-10-17-42(26)35(49)30(21(5)6)41-32(46)25(19-27(36)43)39-34(48)29(20(3)4)40-31(45)24(38-28(44)8-2)18-22-12-14-23(15-13-22)53-54(50,51)52/h12-15,20-21,24-26,29-30H,7-11,16-19H2,1-6H3,(H2,36,43)(H,37,47)(H,38,44)(H,39,48)(H,40,45)(H,41,46)(H2,50,51,52)/t24-,25-,26-,29-,30-/m0/s1 URJZOVGTFURSPL-IJUWOWPVSA-N 50074713 CHEMBL367276::Phosphoric acid mono-{4-[(S)-2-((S)-1-{(S)-1-[(S)-1-((S)-2-butylcarbamoyl-pyrrolidine-1-carbonyl)-2-methyl-propylcarbamoyl]-2-carbamoyl-ethylcarbamoyl}-2-methyl-propylcarbamoyl)-2-propionylamino-ethyl]-phenyl} ester Growth factor receptor-bound protein 2 Homo sapiens 1630 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074713&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10629055 103967905 CHEMBL367276 C01167 ZINC95612649 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129594 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)NC(C)=O InChI=1S/C36H55N8O12P/c1-19(2)29-35(51)41-26(18-28(37)46)33(49)43-30(20(3)4)36(52)44-16-8-10-27(44)34(50)38-15-7-6-9-24(39-21(5)45)31(47)40-25(32(48)42-29)17-22-11-13-23(14-12-22)56-57(53,54)55/h11-14,19-20,24-27,29-30H,6-10,15-18H2,1-5H3,(H2,37,46)(H,38,50)(H,39,45)(H,40,47)(H,41,51)(H,42,48)(H,43,49)(H2,53,54,55)/t24-,25+,26+,27+,29-,30-/m0/s1 ZFXYMDBTOLQWLR-BMBVYFOJSA-N 50074710 CHEMBL435910::Phosphoric acid mono-[4-((5S,8R,11S,14R,17S,23aR)-17-acetylamino-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,23-hexaoxo-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 70.0 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074710&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386472 103967902 CHEMBL435910 ZINC95614534 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129595 CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCC(O)=O)[C@@H](C)CC)C(O)=O InChI=1S/C51H77N10O21P/c1-5-26(3)41(50(76)61-24-8-10-36(61)48(74)59-42(51(77)78)27(4)6-2)58-45(71)33(18-22-40(67)68)54-43(69)32(17-21-39(65)66)55-46(72)34(25-28-11-13-29(14-12-28)82-83(79,80)81)57-44(70)31(16-19-37(53)62)56-47(73)35-9-7-23-60(35)49(75)30(52)15-20-38(63)64/h11-14,26-27,30-36,41-42H,5-10,15-25,52H2,1-4H3,(H2,53,62)(H,54,69)(H,55,72)(H,56,73)(H,57,70)(H,58,71)(H,59,74)(H,63,64)(H,65,66)(H,67,68)(H,77,78)(H2,79,80,81)/t26-,27-,30-,31-,32-,33-,34-,35-,36-,41-,42-/m0/s1 NMPJRPMYJUNRJO-UUBMMGQGSA-N 50074714 CHEMBL263347::Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile Growth factor receptor-bound protein 2 Homo sapiens 6300 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074714&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387060 103967906 CHEMBL263347 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129596 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)NC(C)=O InChI=1S/C36H55N8O12P/c1-19(2)29-35(51)41-26(18-28(37)46)33(49)43-30(20(3)4)36(52)44-16-8-10-27(44)34(50)38-15-7-6-9-24(39-21(5)45)31(47)40-25(32(48)42-29)17-22-11-13-23(14-12-22)56-57(53,54)55/h11-14,19-20,24-27,29-30H,6-10,15-18H2,1-5H3,(H2,37,46)(H,38,50)(H,39,45)(H,40,47)(H,41,51)(H,42,48)(H,43,49)(H2,53,54,55)/t24-,25-,26-,27-,29+,30+/m1/s1 ZFXYMDBTOLQWLR-WOMNCXHOSA-N 50074705 CHEMBL359934::Phosphoric acid mono-[4-((5S,8R,11S,14R,17R,23aR)-17-acetylamino-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,23-hexaoxo-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 180 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074705&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386635 103967897 CHEMBL359934 ZINC95612356 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129597 CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(C)C)NC(C)=S InChI=1S/C36H55N8O11PS/c1-19(2)29-35(50)41-26(18-28(37)45)33(48)43-30(20(3)4)36(51)44-16-8-10-27(44)34(49)38-15-7-6-9-24(39-21(5)57)31(46)40-25(32(47)42-29)17-22-11-13-23(14-12-22)55-56(52,53)54/h11-14,19-20,24-27,29-30H,6-10,15-18H2,1-5H3,(H2,37,45)(H,38,49)(H,39,57)(H,40,46)(H,41,50)(H,42,47)(H,43,48)(H2,52,53,54)/t24-,25+,26+,27+,29-,30-/m0/s1 HWIHFQSDJBSOLW-BMBVYFOJSA-N 50074715 CHEMBL433805::Phosphoric acid mono-[4-((5S,8R,11S,14R,17S,23aR)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,23-hexaoxo-17-thioacetylamino-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 60 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074715&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44385763 103967907 CHEMBL433805 ZINC95614708 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129598 CC(C)[C@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(C)C InChI=1S/C30H44N7O11P/c1-15(2)24-29(43)34-20(13-22(31)38)27(41)36-25(16(3)4)30(44)37-11-5-6-21(37)28(42)32-14-23(39)33-19(26(40)35-24)12-17-7-9-18(10-8-17)48-49(45,46)47/h7-10,15-16,19-21,24-25H,5-6,11-14H2,1-4H3,(H2,31,38)(H,32,42)(H,33,39)(H,34,43)(H,35,40)(H,36,41)(H2,45,46,47)/t19-,20-,21+,24+,25+/m0/s1 LEIBQLDKRFRHEP-IRZMIGAXSA-N 50074707 CHEMBL174819::Phosphoric acid mono-[4-((5R,8S,11R,14S,19aR)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,19-hexaoxo-octadecahydro-3a,6,9,12,15,18-hexaaza-cyclopentacyclooctadecen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 10830 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074707&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386412 103967899 CHEMBL174819 ZINC28099452 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129601 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C57H80N11O17P/c1-32(2)47(54(77)61-39(24-25-46(70)71)49(72)65-43(57(80)81)30-35-16-9-6-10-17-35)67-52(75)42(31-45(60)69)64-55(78)48(33(3)4)66-51(74)41(29-36-20-22-37(23-21-36)85-86(82,83)84)62-50(73)40(28-34-14-7-5-8-15-34)63-53(76)44-19-13-27-68(44)56(79)38(59)18-11-12-26-58/h5-10,14-17,20-23,32-33,38-44,47-48H,11-13,18-19,24-31,58-59H2,1-4H3,(H2,60,69)(H,61,77)(H,62,73)(H,63,76)(H,64,78)(H,65,72)(H,66,74)(H,67,75)(H,70,71)(H,80,81)(H2,82,83,84)/t38-,39-,40-,41-,42-,43-,44-,47-,48-/m0/s1 NQEUDXBNCYJDFJ-CKNONNRWSA-N 50074716 CHEMBL438943::Lys-Pro-Phe-pTyr-Val-Asn-Val-Glu-Phe Growth factor receptor-bound protein 2 Homo sapiens 140 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074716&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 444601 103967908 CHEMBL438943 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129604 CC(C)[C@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)OCCCCCNC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(C)C InChI=1S/C34H52N7O12P/c1-19(2)27-32(46)37-24(18-26(35)42)30(44)40-28(20(3)4)33(47)41-15-8-9-25(41)31(45)36-14-6-5-7-16-52-34(48)38-23(29(43)39-27)17-21-10-12-22(13-11-21)53-54(49,50)51/h10-13,19-20,23-25,27-28H,5-9,14-18H2,1-4H3,(H2,35,42)(H,36,45)(H,37,46)(H,38,48)(H,39,43)(H,40,44)(H2,49,50,51)/t23-,24-,25-,27+,28+/m0/s1 IFOJZLPAQJIDJH-BJPVBTOCSA-N 50074704 CHEMBL435738::Phosphoric acid mono-[4-((5R,8S,11R,14S,24aS)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,24-hexaoxo-docosahydro-17-oxa-3a,6,9,12,15,23-hexaaza-cyclopentacyclotricosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 710 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074704&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386471 103967896 CHEMBL435738 ZINC95614694 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50129607 CC(C)[C@@H]1NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C1=O)NC(C)=O InChI=1S/C40H61N8O12P/c1-23(2)34-40(56)48-19-9-13-32(48)39(55)42-18-8-7-12-28(43-24(3)49)35(51)44-30(21-26-14-16-27(17-15-26)60-61(57,58)59)36(52)45-29(20-25-10-5-4-6-11-25)37(53)46-31(22-33(41)50)38(54)47-34/h14-17,23,25,28-32,34H,4-13,18-22H2,1-3H3,(H2,41,50)(H,42,55)(H,43,49)(H,44,51)(H,45,52)(H,46,53)(H,47,54)(H2,57,58,59)/t28-,29-,30+,31+,32+,34-/m0/s1 HKEVLHGHDIEVSN-ZCQNOMNMSA-N 50074717 CHEMBL451250::Phosphoric acid mono-[4-((5S,8R,11S,14R,17S,23aR)-17-acetylamino-8-carbamoylmethyl-11-cyclohexylmethyl-5-isopropyl-4,7,10,13,16,23-hexaoxo-docosahydro-3a,6,9,12,15,22-hexaaza-cyclopentacyclodocosen-14-ylmethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 1610 ChEMBL 10.1021/jm9811007 10.7270/Q28S4P35 10090780 Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Novartis Forschungsinstitut http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074717&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44386410 103967909 CHEMBL451250 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128136 COc1ccc2c(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)c[nH]c2c1 InChI=1S/C35H47N6O9P/c1-22(42)39-29(17-23-8-10-24(11-9-23)21-51(47,48)49)33(45)41-35(14-4-3-5-15-35)34(46)40-30(19-31(36)43)32(44)37-16-6-7-25-20-38-28-18-26(50-2)12-13-27(25)28/h8-13,18,20,29-30,38H,3-7,14-17,19,21H2,1-2H3,(H2,36,43)(H,37,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t29-,30-/m0/s1 NCIUVOQQMYXQDZ-KYJUHHDHSA-N 50073908 CHEMBL70852::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(6-methoxy-1H-indol-3-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 14 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073908&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312278 103967192 CHEMBL70852 ZINC26295927 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128137 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 InChI=1S/C35H47N6O8P/c1-23-7-12-30-27(19-23)13-18-41(30)17-6-16-37-32(44)29(21-31(36)43)39-34(46)35(14-4-3-5-15-35)40-33(45)28(38-24(2)42)20-25-8-10-26(11-9-25)22-50(47,48)49/h7-13,18-19,28-29H,3-6,14-17,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 DLQYBJRFYUMKRJ-VMPREFPWSA-N 50073909 CHEMBL72036::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid::{4-[2-Acetylamino-2-(1-{2-carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 0.400000 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073909&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10417376 103967193 CHEMBL72036 ZINC26376167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128138 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(Cl)ccc12 InChI=1S/C34H44ClN6O8P/c1-22(42)38-27(18-23-6-8-24(9-7-23)21-50(47,48)49)32(45)40-34(13-3-2-4-14-34)33(46)39-28(20-30(36)43)31(44)37-15-5-16-41-17-12-25-19-26(35)10-11-29(25)41/h6-12,17,19,27-28H,2-5,13-16,18,20-21H2,1H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t27-,28-/m0/s1 IHAHKOBLYCNBRD-NSOVKSMOSA-N 50073910 CHEMBL431381::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-chloro-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 59 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073910&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312280 103967194 CHEMBL431381 ZINC26376169 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128139 CN(C)c1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)ccc2c1 InChI=1S/C36H50N7O8P/c1-24(44)39-29(20-25-8-10-26(11-9-25)23-52(49,50)51)34(47)41-36(15-5-4-6-16-36)35(48)40-30(22-32(37)45)33(46)38-17-7-18-43-19-14-27-21-28(42(2)3)12-13-31(27)43/h8-14,19,21,29-30H,4-7,15-18,20,22-23H2,1-3H3,(H2,37,45)(H,38,46)(H,39,44)(H,40,48)(H,41,47)(H2,49,50,51)/t29-,30-/m0/s1 LOXFCSUCNZKZGQ-KYJUHHDHSA-N 50073911 CHEMBL72525::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-dimethylamino-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 3.4 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073911&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44311997 103967195 CHEMBL72525 ZINC26376579 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128140 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(O)ccc12 InChI=1S/C34H45N6O9P/c1-22(41)37-27(18-23-6-8-24(9-7-23)21-50(47,48)49)32(45)39-34(13-3-2-4-14-34)33(46)38-28(20-30(35)43)31(44)36-15-5-16-40-17-12-25-19-26(42)10-11-29(25)40/h6-12,17,19,27-28,42H,2-5,13-16,18,20-21H2,1H3,(H2,35,43)(H,36,44)(H,37,41)(H,38,46)(H,39,45)(H2,47,48,49)/t27-,28-/m0/s1 KTEIKJDTMFXKOP-NSOVKSMOSA-N 50073913 CHEMBL73003::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-hydroxy-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 0.300000 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073913&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10327480 103967197 CHEMBL73003 ZINC26379218 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128141 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cn(C)c2ccccc12 InChI=1S/C35H47N6O8P/c1-23(42)38-28(19-24-12-14-25(15-13-24)22-50(47,48)49)33(45)40-35(16-6-3-7-17-35)34(46)39-29(20-31(36)43)32(44)37-18-8-9-26-21-41(2)30-11-5-4-10-27(26)30/h4-5,10-15,21,28-29H,3,6-9,16-20,22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 QSIYXZBMPMBUJQ-VMPREFPWSA-N 50073912 CHEMBL72996::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(1-methyl-1H-indol-3-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 9.2 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073912&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312305 103967196 CHEMBL72996 ZINC26378901 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128142 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1c(C)cc2ccccc12 InChI=1S/C35H47N6O8P/c1-23-19-27-9-4-5-10-30(27)41(23)18-8-17-37-32(44)29(21-31(36)43)39-34(46)35(15-6-3-7-16-35)40-33(45)28(38-24(2)42)20-25-11-13-26(14-12-25)22-50(47,48)49/h4-5,9-14,19,28-29H,3,6-8,15-18,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 VCDSLHCXSZNLDF-VMPREFPWSA-N 50073916 CHEMBL72437::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(2-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 15 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073916&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44311847 103967200 CHEMBL72437 ZINC26378705 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128143 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1cc(C)c2ccccc12 InChI=1S/C35H47N6O8P/c1-23-21-41(30-10-5-4-9-27(23)30)18-8-17-37-32(44)29(20-31(36)43)39-34(46)35(15-6-3-7-16-35)40-33(45)28(38-24(2)42)19-25-11-13-26(14-12-25)22-50(47,48)49/h4-5,9-14,21,28-29H,3,6-8,15-20,22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 KELHZTVETRVDHZ-VMPREFPWSA-N 50073915 CHEMBL72114::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(3-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 81 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073915&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44311999 103967199 CHEMBL72114 ZINC26376584 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128144 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1c[nH]c2ccccc12 InChI=1S/C34H45N6O8P/c1-22(41)38-28(18-23-11-13-24(14-12-23)21-49(46,47)48)32(44)40-34(15-5-2-6-16-34)33(45)39-29(19-30(35)42)31(43)36-17-7-8-25-20-37-27-10-4-3-9-26(25)27/h3-4,9-14,20,28-29,37H,2,5-8,15-19,21H2,1H3,(H2,35,42)(H,36,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t28-,29-/m0/s1 IVCRWGVZPCJVLK-VMPREFPWSA-N 50073914 CHEMBL71034::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(1H-indol-3-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 155 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073914&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312279 103967198 CHEMBL71034 ZINC26293508 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128145 COc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)ccc2c1 InChI=1S/C35H47N6O9P/c1-23(42)38-28(19-24-7-9-25(10-8-24)22-51(47,48)49)33(45)40-35(14-4-3-5-15-35)34(46)39-29(21-31(36)43)32(44)37-16-6-17-41-18-13-26-20-27(50-2)11-12-30(26)41/h7-13,18,20,28-29H,3-6,14-17,19,21-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 KXTNXHLYXOXMOA-VMPREFPWSA-N 50073917 CHEMBL72694::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-methoxy-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 0.900000 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073917&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44311998 103967201 CHEMBL72694 ZINC26376581 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50128146 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2ccccc12 InChI=1S/C34H45N6O8P/c1-23(41)37-27(20-24-10-12-25(13-11-24)22-49(46,47)48)32(44)39-34(15-5-2-6-16-34)33(45)38-28(21-30(35)42)31(43)36-17-7-18-40-19-14-26-8-3-4-9-29(26)40/h3-4,8-14,19,27-28H,2,5-7,15-18,20-22H2,1H3,(H2,35,42)(H,36,43)(H,37,41)(H,38,45)(H,39,44)(H2,46,47,48)/t27-,28-/m0/s1 UWZBIKDYMUJFTN-NSOVKSMOSA-N 50073918 CHEMBL431982::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-indol-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 1.2 ChEMBL 10.1016/s0960-894x(98)00701-x 10.7270/Q2N58KJG 10021933 Schoepfer, J; Fretz, H; Gay, B; Furet, P; Garcia-Echeverria, C; End, N; Caravatti, G Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073918&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312233 103967202 CHEMBL431982 ZINC26377455 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130318 CC(=O)N[C@H](Cc1ccc(cc1)C(F)(F)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43F2N5O7/c1-23(45)42-29(21-24-14-16-27(17-15-24)37(38,39)35(50)51)33(48)44-36(18-5-2-6-19-36)34(49)43-30(22-31(40)46)32(47)41-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,40,46)(H,41,47)(H,42,45)(H,43,49)(H,44,48)(H,50,51)/t29-,30+/m1/s1 ZQCBHKMISVQNEE-IHLOFXLRSA-N 50075010 CHEMBL332992::[4-((R)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-difluoro-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 28000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075010&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344729 103968202 CHEMBL332992 ZINC27105162 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130319 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](Cc1ccc(CC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O9/c38-30(43)22-29(32(46)39-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-24(16-14-23)21-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29+/m1/s1 XYXSUXVWOJXCIE-WDYNHAJCSA-N 50075011 CHEMBL331638::N-[(R)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 600 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075011&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344501 103968203 CHEMBL331638 C03768 ZINC27105625 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130320 CC(=O)N[C@H](Cc1ccc(CC(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H45N5O7/c1-24(43)40-30(21-25-14-16-26(17-15-25)22-33(45)46)35(48)42-37(18-5-2-6-19-37)36(49)41-31(23-32(38)44)34(47)39-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,38,44)(H,39,47)(H,40,43)(H,41,49)(H,42,48)(H,45,46)/t30-,31+/m1/s1 MNNBOBOXKZOXSF-JSOSNVBQSA-N 50075012 CHEMBL432984::[4-((R)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2500 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075012&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344477 103968204 CHEMBL432984 C03768 ZINC27094627 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130321 NC(Cc1ccc(cc1)C(F)(F)C(O)=O)C(O)=O InChI=1S/C11H11F2NO4/c12-11(13,10(17)18)7-3-1-6(2-4-7)5-8(14)9(15)16/h1-4,8H,5,14H2,(H,15,16)(H,17,18) NBXNKWBCCAIMRX-UHFFFAOYSA-N 50075013 2-Amino-3-[4-(carboxy-difluoro-methyl)-phenyl]-propionic acid::CHEMBL119885 Growth factor receptor-bound protein 2 Homo sapiens 28000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075013&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344773 103968205 CHEMBL119885 ZINC27104164 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130322 NC(Cc1ccc(OCC(O)=O)cc1)C(O)=O InChI=1S/C11H13NO5/c12-9(11(15)16)5-7-1-3-8(4-2-7)17-6-10(13)14/h1-4,9H,5-6,12H2,(H,13,14)(H,15,16) ARXFMTURSPNMGH-UHFFFAOYSA-N 50075014 2-Amino-3-(4-carboxymethoxy-phenyl)-propionic acid::CHEMBL117514 Growth factor receptor-bound protein 2 Homo sapiens 2500 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075014&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344577 103968206 CHEMBL117514 ZINC27100575 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130323 CC(=O)N[C@H](Cc1ccc(OCC(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H45N5O8/c1-24(43)40-30(21-25-14-16-28(17-15-25)50-23-33(45)46)35(48)42-37(18-5-2-6-19-37)36(49)41-31(22-32(38)44)34(47)39-20-8-12-27-11-7-10-26-9-3-4-13-29(26)27/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,38,44)(H,39,47)(H,40,43)(H,41,49)(H,42,48)(H,45,46)/t30-,31+/m1/s1 JDPYMLPVGSMNKO-JSOSNVBQSA-N 50075015 CHEMBL333421::[4-((R)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 65000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075015&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344500 103968207 CHEMBL333421 ZINC27105622 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130324 NC(Cc1ccc(CC(O)=O)cc1)C(O)=O InChI=1S/C11H13NO4/c12-9(11(15)16)5-7-1-3-8(4-2-7)6-10(13)14/h1-4,9H,5-6,12H2,(H,13,14)(H,15,16) LJHYWUVYIKCPGU-UHFFFAOYSA-N 50075016 2-Amino-3-(4-carboxymethyl-phenyl)-propionic acid::CHEMBL119492 Growth factor receptor-bound protein 2 Homo sapiens 65000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075016&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 1PA 4X6S,5U06,1BHF,2N3Y 4469363 103968208 CHEMBL119492 C03768 ZINC06506146 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130325 CC(=O)N[C@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30+/m1/s1 ATTZUIWVKJIUFV-IHLOFXLRSA-N 50075017 CHEMBL332862::Phosphoric acid mono-[4-((R)-2-acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 7.0 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075017&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344728 103968209 CHEMBL332862 ZINC27105159 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130326 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](Cc1ccc(cc1)C(F)(F)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H41F2N5O9/c38-37(39,35(52)53)25-15-13-22(14-16-25)20-27(42-32(48)33(49)50)31(47)44-36(17-4-1-5-18-36)34(51)43-28(21-29(40)45)30(46)41-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24/h2-3,6,8-10,12-16,27-28H,1,4-5,7,11,17-21H2,(H2,40,45)(H,41,46)(H,42,48)(H,43,51)(H,44,47)(H,49,50)(H,52,53)/t27-,28+/m1/s1 NLLHKIHZRXWCPN-IZLXSDGUSA-N 50075018 CHEMBL327030::{4-[(R)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-difluoro-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075018&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344748 103968210 CHEMBL327030 ZINC27109229 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50130327 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](Cc1ccc(OCC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O10/c38-30(43)21-29(32(46)39-19-7-11-25-10-6-9-24-8-2-3-12-27(24)25)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-26(16-14-23)52-22-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29+/m1/s1 OZMYXAMTIOVAPK-WDYNHAJCSA-N 50075019 CHEMBL430710::N-[(R)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethoxy-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 15000 ChEMBL 10.1016/s0960-894x(98)00740-9 10.7270/Q2VM4BF2 10091682 Burke, TR; Luo, J; Yao, ZJ; Gao, Y; Zhao, H; Milne, GW; Guo, R; Voigt, JH; King, CR; Yang, D National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075019&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44344738 103968211 CHEMBL430710 ZINC27100027 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50136879 NC(=O)[C@@H]1CCC=C[C@@H]1NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1 InChI=1S/C31H40N5O9P/c32-22-8-6-7-21(17-22)19-44-30(40)35-26(18-20-11-13-23(14-12-20)45-46(41,42)43)28(38)36-31(15-4-1-5-16-31)29(39)34-25-10-3-2-9-24(25)27(33)37/h3,6-8,10-14,17,24-26H,1-2,4-5,9,15-16,18-19,32H2,(H2,33,37)(H,34,39)(H,35,40)(H,36,38)(H2,41,42,43)/t24-,25+,26+/m1/s1 YENDXPUMHXTISG-ZNZIZOMTSA-N 50078346 CHEMBL310056::[(S)-1-[1-((1S,6R)-6-Carbamoyl-cyclohex-2-enylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens >5000 ChEMBL 10.1021/jm991013u 10.7270/Q2S181PH 10395476 Furet, P; Garcia-Echeverria, C; Gay, B; Schoepfer, J; Zeller, M; Rahuel, J Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078346&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44315649 103970938 CHEMBL310056 C01167 ZINC26470553 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50136880 NC(=O)[C@H]1CCC=C[C@H]1NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1 InChI=1S/C31H40N5O9P/c32-22-8-6-7-21(17-22)19-44-30(40)35-26(18-20-11-13-23(14-12-20)45-46(41,42)43)28(38)36-31(15-4-1-5-16-31)29(39)34-25-10-3-2-9-24(25)27(33)37/h3,6-8,10-14,17,24-26H,1-2,4-5,9,15-16,18-19,32H2,(H2,33,37)(H,34,39)(H,35,40)(H,36,38)(H2,41,42,43)/t24-,25+,26-/m0/s1 YENDXPUMHXTISG-NXCFDTQHSA-N 50078347 CHEMBL307890::[(S)-1-[1-((1R,6S)-6-Carbamoyl-cyclohex-2-enylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 1.6 ChEMBL 10.1021/jm991013u 10.7270/Q2S181PH 10395476 Furet, P; Garcia-Echeverria, C; Gay, B; Schoepfer, J; Zeller, M; Rahuel, J Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078347&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 444832 103970939 CHEMBL307890 C01167 ZINC26403548 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50136881 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42)/t21-,22-/m0/s1 XWNQRYAPQUFUMS-VXKWHMMOSA-N 50078348 CHEMBL77689::[(S)-1-[1-((S)-1,2-Dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 1 ChEMBL 10.1021/jm991013u 10.7270/Q2S181PH 10395476 Furet, P; Garcia-Echeverria, C; Gay, B; Schoepfer, J; Zeller, M; Rahuel, J Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078348&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10349262 103970940 CHEMBL77689 C01167 ZINC26394430 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140282 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc2ccc(OC(C(O)=O)C(O)=O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C62H82N12O21S2/c1-30(2)22-40-55(85)71-42(24-32-6-12-35(75)13-7-32)57(87)68-38(18-19-49(80)81)53(83)72-44(26-46(63)77)59(89)74-50(31(3)4)60(90)65-27-47(78)66-39(20-21-96-5)54(84)70-43(25-33-8-14-36(76)15-9-33)58(88)73-45(52(64)82)28-97-29-48(79)67-41(56(86)69-40)23-34-10-16-37(17-11-34)95-51(61(91)92)62(93)94/h6-17,30-31,38-45,50-51,75-76H,18-29H2,1-5H3,(H2,63,77)(H2,64,82)(H,65,90)(H,66,78)(H,67,79)(H,68,87)(H,69,86)(H,70,84)(H,71,85)(H,72,83)(H,73,88)(H,74,89)(H,80,81)(H,91,92)(H,93,94)/t38-,39-,40-,41-,42-,43-,44-,45-,50-/m1/s1 SJWIXULSXVRBJX-IGDSTCQPSA-N 50080118 CHEMBL441328::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 64500 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080118&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312720 103980298 CHEMBL441328 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140283 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCCC(O)=O)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C56H80N12O18S2/c1-28(2)21-37-52(82)65-38(22-30-9-13-32(69)14-10-30)53(83)62-35(17-18-46(76)77)50(80)66-40(24-42(57)71)55(85)68-47(29(3)4)56(86)59-25-43(72)60-36(19-20-87-5)51(81)64-39(23-31-11-15-33(70)16-12-31)54(84)67-41(48(58)78)26-88-27-44(73)61-34(49(79)63-37)7-6-8-45(74)75/h9-16,28-29,34-41,47,69-70H,6-8,17-27H2,1-5H3,(H2,57,71)(H2,58,78)(H,59,86)(H,60,72)(H,61,73)(H,62,83)(H,63,79)(H,64,81)(H,65,82)(H,66,80)(H,67,84)(H,68,85)(H,74,75)(H,76,77)/t34-,35-,36-,37-,38-,39-,40-,41-,47-/m1/s1 KVUJLUPYNZQNSN-YNLZADKXSA-N 50080119 CHEMBL412817::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 3450 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080119&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312499 103980299 CHEMBL412817 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140284 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCC(O)=O)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H79N12O21PS2/c1-27(2)20-36-51(80)64-37(21-29-6-10-31(68)11-7-29)52(81)61-34(15-17-45(74)75)49(78)65-39(23-41(56)69)54(83)67-46(28(3)4)55(84)58-24-42(70)59-35(18-19-90-5)50(79)63-38(22-30-8-12-32(13-9-30)88-89(85,86)87)53(82)66-40(47(57)76)25-91-26-43(71)60-33(48(77)62-36)14-16-44(72)73/h6-13,27-28,33-40,46,68H,14-26H2,1-5H3,(H2,56,69)(H2,57,76)(H,58,84)(H,59,70)(H,60,71)(H,61,81)(H,62,77)(H,63,79)(H,64,80)(H,65,78)(H,66,82)(H,67,83)(H,72,73)(H,74,75)(H2,85,86,87)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m1/s1 KKZVESHDBCGZRG-GLSZOLDUSA-N 50080120 CHEMBL409686::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 130 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080120&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312400 103980300 CHEMBL409686 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140285 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C56H78N12O20S2/c1-26(2)18-35-49(79)65-36(19-28-6-10-30(69)11-7-28)50(80)62-33(14-15-44(74)75)47(77)66-39(22-41(57)71)53(83)68-45(27(3)4)54(84)59-23-42(72)60-34(16-17-89-5)48(78)64-37(20-29-8-12-31(70)13-9-29)51(81)67-40(46(58)76)24-90-25-43(73)61-38(52(82)63-35)21-32(55(85)86)56(87)88/h6-13,26-27,32-40,45,69-70H,14-25H2,1-5H3,(H2,57,71)(H2,58,76)(H,59,84)(H,60,72)(H,61,73)(H,62,80)(H,63,82)(H,64,78)(H,65,79)(H,66,77)(H,67,81)(H,68,83)(H,74,75)(H,85,86)(H,87,88)/t33-,34-,35-,36-,37-,38-,39-,40-,45-/m1/s1 WUIYUDVETVSNJA-UJEZNLSCSA-N 50080121 CHEMBL411591::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 640 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080121&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312498 103980301 CHEMBL411591 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140286 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C53H77N12O19PS2/c1-26(2)19-35-49(76)62-36(20-29-7-11-31(66)12-8-29)50(77)59-33(15-16-43(70)71)47(74)63-38(22-40(54)67)52(79)65-44(27(3)4)53(80)56-23-41(68)58-34(17-18-86-6)48(75)61-37(21-30-9-13-32(14-10-30)84-85(81,82)83)51(78)64-39(45(55)72)24-87-25-42(69)57-28(5)46(73)60-35/h7-14,26-28,33-39,44,66H,15-25H2,1-6H3,(H2,54,67)(H2,55,72)(H,56,80)(H,57,69)(H,58,68)(H,59,77)(H,60,73)(H,61,75)(H,62,76)(H,63,74)(H,64,78)(H,65,79)(H,70,71)(H2,81,82,83)/t28-,33-,34-,35-,36-,37-,38-,39-,44-/m1/s1 IBBAKMGKCRCQFI-RCOQGGFDSA-N 50080122 CHEMBL407859::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 23 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080122&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312719 103980302 CHEMBL407859 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140287 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CCC(O)=O)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m1/s1 BZLRZJFFHMIABH-GLSZOLDUSA-N 50080123 CHEMBL405106::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 20000 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080123&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312398 103980303 CHEMBL405106 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140288 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C53H76N12O16S2/c1-26(2)19-35-49(77)62-36(20-29-7-11-31(66)12-8-29)50(78)59-33(15-16-43(71)72)47(75)63-38(22-40(54)68)52(80)65-44(27(3)4)53(81)56-23-41(69)58-34(17-18-82-6)48(76)61-37(21-30-9-13-32(67)14-10-30)51(79)64-39(45(55)73)24-83-25-42(70)57-28(5)46(74)60-35/h7-14,26-28,33-39,44,66-67H,15-25H2,1-6H3,(H2,54,68)(H2,55,73)(H,56,81)(H,57,70)(H,58,69)(H,59,78)(H,60,74)(H,61,76)(H,62,77)(H,63,75)(H,64,79)(H,65,80)(H,71,72)/t28-,33-,34-,35-,36-,37-,38-,39-,44-/m1/s1 BSBGHKQDUYBGIR-RCOQGGFDSA-N 50080124 CHEMBL407228::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 100000 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080124&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312399 103980304 CHEMBL407228 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50140289 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C59H81N12O20PS2/c1-30(2)22-40-54(82)68-42(24-32-6-12-35(72)13-7-32)56(84)65-38(18-19-49(77)78)52(80)69-44(26-46(60)74)58(86)71-50(31(3)4)59(87)62-27-47(75)63-39(20-21-93-5)53(81)67-43(25-33-8-14-36(73)15-9-33)57(85)70-45(51(61)79)28-94-29-48(76)64-41(55(83)66-40)23-34-10-16-37(17-11-34)91-92(88,89)90/h6-17,30-31,38-45,50,72-73H,18-29H2,1-5H3,(H2,60,74)(H2,61,79)(H,62,87)(H,63,75)(H,64,76)(H,65,84)(H,66,83)(H,67,81)(H,68,82)(H,69,80)(H,70,85)(H,71,86)(H,77,78)(H2,88,89,90)/t38-,39-,40-,41-,42-,43-,44-,45-,50-/m1/s1 VDYKUNBFSFRIKU-IGDSTCQPSA-N 50080125 CHEMBL414817::Cyclo peptide analogue Growth factor receptor-bound protein 2 Homo sapiens 27500 ChEMBL 10.1016/s0960-894x(99)00379-0 10.7270/Q2VH5N1R 10465559 Long, YQ; Voigt, JH; Lung, FD; King, CR; Roller, PP National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080125&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44312721 103980305 CHEMBL414817 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50139393 Nc1ccnc(NCCc2ccc(OP(O)(O)=O)cc2)n1 InChI=1S/C12H15N4O4P/c13-11-6-8-15-12(16-11)14-7-5-9-1-3-10(4-2-9)20-21(17,18)19/h1-4,6,8H,5,7H2,(H2,17,18,19)(H3,13,14,15,16) JTAYIVWOJFEPLW-UHFFFAOYSA-N 50079647 CHEMBL291304::Phosphoric acid mono-{4-[2-(4-amino-pyrimidin-2-ylamino)-ethyl]-phenyl} ester Growth factor receptor-bound protein 2 Homo sapiens >200000 ChEMBL 10.1016/s0960-894x(99)00299-1 10.7270/Q26W9985 10450965 Caravatti, G; Rahuel, J; Gay, B; Furet, P Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079647&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 15546819 103971789 CHEMBL291304 ZINC29567130 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50139394 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C17H24N5O9P/c1-9(23)21-13(6-10-2-4-11(5-3-10)31-32(28,29)30)17(27)20-8-15(25)22-12(16(19)26)7-14(18)24/h2-5,12-13H,6-8H2,1H3,(H2,18,24)(H2,19,26)(H,20,27)(H,21,23)(H,22,25)(H2,28,29,30)/t12-,13-/m0/s1 VEXZKKOEFKAIQW-STQMWFEESA-N 50072186 CHEMBL61047::Phosphoric acid mono-[4-((S)-2-acetylamino-2-{[((S)-1,2-dicarbamoyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 67000 ChEMBL 10.1016/s0960-894x(99)00299-1 10.7270/Q26W9985 10450965 Caravatti, G; Rahuel, J; Gay, B; Furet, P Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072186&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44302560 103965838 CHEMBL61047 C01167 ZINC26158594 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50139395 Cc1sc(nc1-c1ccc(OP(O)(O)=O)cc1)-c1nccc(N)n1 InChI=1S/C14H13N4O4PS/c1-8-12(9-2-4-10(5-3-9)22-23(19,20)21)18-14(24-8)13-16-7-6-11(15)17-13/h2-7H,1H3,(H2,15,16,17)(H2,19,20,21) JVVRWWWRERDYBF-UHFFFAOYSA-N 50079648 CHEMBL61048::Phosphoric acid mono-{4-[2-(4-amino-pyrimidin-2-yl)-5-methyl-thiazol-4-yl]-phenyl} ester Growth factor receptor-bound protein 2 Homo sapiens 25900 ChEMBL 10.1016/s0960-894x(99)00299-1 10.7270/Q26W9985 10450965 Caravatti, G; Rahuel, J; Gay, B; Furet, P Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079648&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10384143 103971790 CHEMBL61048 ZINC26158602 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50139396 CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C20H30N5O9P/c1-10(2)17(20(30)24-14(18(22)28)9-16(21)27)25-19(29)15(23-11(3)26)8-12-4-6-13(7-5-12)34-35(31,32)33/h4-7,10,14-15,17H,8-9H2,1-3H3,(H2,21,27)(H2,22,28)(H,23,26)(H,24,30)(H,25,29)(H2,31,32,33)/t14-,15-,17-/m0/s1 GSJUDVVVSUJCMF-ZOBUZTSGSA-N 50072184 CHEMBL292567::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-propylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 4320.0 ChEMBL 10.1016/s0960-894x(99)00299-1 10.7270/Q26W9985 10450965 Caravatti, G; Rahuel, J; Gay, B; Furet, P Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072184&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44302277 103965836 CHEMBL292567 C01167 ZINC26156308 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141747 NC(=O)CC(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C30H36N6O14P2/c31-20-3-1-2-19(12-20)16-48-30(41)36-25(14-18-6-10-22(11-7-18)50-52(45,46)47)29(40)35-24(28(39)34-23(27(33)38)15-26(32)37)13-17-4-8-21(9-5-17)49-51(42,43)44/h1-12,23-25H,13-16,31H2,(H2,32,37)(H2,33,38)(H,34,39)(H,35,40)(H,36,41)(H2,42,43,44)(H2,45,46,47) VFFIMVRXRYNDCN-UHFFFAOYSA-N 50080830 CHEMBL333070::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 235 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080830&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348525 103980954 CHEMBL333070 ZINC95611131 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141748 NC(=O)CC(NC(=O)C1(CCCCC1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42) XWNQRYAPQUFUMS-UHFFFAOYSA-N 50080831 CHEMBL434413::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 30 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080831&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348294 103980955 CHEMBL434413 ZINC27202638 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141749 CC(Cc1ccc(OP(O)(O)=O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C31H38N6O14P2/c1-31(29(41)35-24(27(34)39)15-26(33)38,16-19-7-11-23(12-8-19)51-53(46,47)48)37-28(40)25(14-18-5-9-22(10-6-18)50-52(43,44)45)36-30(42)49-17-20-3-2-4-21(32)13-20/h2-13,24-25H,14-17,32H2,1H3,(H2,33,38)(H2,34,39)(H,35,41)(H,36,42)(H,37,40)(H2,43,44,45)(H2,46,47,48) CKYOLFFASNEHIT-UHFFFAOYSA-N 50080832 CHEMBL334099::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-1-methyl-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 11 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080832&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348403 103980956 CHEMBL334099 ZINC95611225 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141750 NC(=O)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C30H35N6O11P/c31-20-3-1-2-19(12-20)16-46-30(42)36-25(14-18-6-10-22(11-7-18)47-48(43,44)45)29(41)35-24(13-17-4-8-21(37)9-5-17)28(40)34-23(27(33)39)15-26(32)38/h1-12,23-25,37H,13-16,31H2,(H2,32,38)(H2,33,39)(H,34,40)(H,35,41)(H,36,42)(H2,43,44,45) XFCUYYUFEKZYMF-UHFFFAOYSA-N 50080833 CHEMBL264635::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 497 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080833&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348295 103980957 CHEMBL264635 ZINC37099215 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141751 CC(Cc1ccc(CC(O)=O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C33H39N6O12P/c1-33(31(45)37-25(29(36)43)16-27(35)40,17-21-7-5-20(6-8-21)15-28(41)42)39-30(44)26(14-19-9-11-24(12-10-19)51-52(47,48)49)38-32(46)50-18-22-3-2-4-23(34)13-22/h2-13,25-26H,14-18,34H2,1H3,(H2,35,40)(H2,36,43)(H,37,45)(H,38,46)(H,39,44)(H,41,42)(H2,47,48,49) RYYRPAZGAHMZGP-UHFFFAOYSA-N 50080834 CHEMBL409455::{4-[2-[2-(3-Amino-benzyloxycarbonylamino)-3-(4-phosphonooxy-phenyl)-propionylamino]-2-(1,2-dicarbamoyl-ethylcarbamoyl)-propyl]-phenyl}-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 60 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080834&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348451 103980958 CHEMBL409455 C03768 ZINC95613579 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141752 NC(=O)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C30H35N6O11P/c31-20-3-1-2-19(12-20)16-46-30(42)36-25(14-18-6-10-22(11-7-18)47-48(43,44)45)29(41)35-24(13-17-4-8-21(37)9-5-17)28(40)34-23(27(33)39)15-26(32)38/h1-12,23-25,37H,13-16,31H2,(H2,32,38)(H2,33,39)(H,34,40)(H,35,41)(H,36,42)(H2,43,44,45) XFCUYYUFEKZYMF-UHFFFAOYSA-N 50080833 CHEMBL264635::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 155 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080833&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348295 103980957 CHEMBL264635 ZINC37099215 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141753 NC(=O)CC(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C30H36N6O14P2/c31-20-3-1-2-19(12-20)16-48-30(41)36-25(14-18-6-10-22(11-7-18)50-52(45,46)47)29(40)35-24(28(39)34-23(27(33)38)15-26(32)37)13-17-4-8-21(9-5-17)49-51(42,43)44/h1-12,23-25H,13-16,31H2,(H2,32,37)(H2,33,38)(H,34,39)(H,35,40)(H,36,41)(H2,42,43,44)(H2,45,46,47) VFFIMVRXRYNDCN-UHFFFAOYSA-N 50080830 CHEMBL333070::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 60 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080830&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348525 103980954 CHEMBL333070 ZINC95611131 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141754 CC(Cc1ccc(OP(O)(O)=O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C31H38N6O14P2/c1-31(29(41)35-24(27(34)39)15-26(33)38,16-19-7-11-23(12-8-19)51-53(46,47)48)37-28(40)25(14-18-5-9-22(10-6-18)50-52(43,44)45)36-30(42)49-17-20-3-2-4-21(32)13-20/h2-13,24-25H,14-17,32H2,1H3,(H2,33,38)(H2,34,39)(H,35,41)(H,36,42)(H,37,40)(H2,43,44,45)(H2,46,47,48) CKYOLFFASNEHIT-UHFFFAOYSA-N 50080832 CHEMBL334099::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-1-methyl-2-(4-phosphonooxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 3 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080832&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348403 103980956 CHEMBL334099 ZINC95611225 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141755 CC(Cc1ccc(CC(O)=O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C33H39N6O12P/c1-33(31(45)37-25(29(36)43)16-27(35)40,17-21-7-5-20(6-8-21)15-28(41)42)39-30(44)26(14-19-9-11-24(12-10-19)51-52(47,48)49)38-32(46)50-18-22-3-2-4-23(34)13-22/h2-13,25-26H,14-18,34H2,1H3,(H2,35,40)(H2,36,43)(H,37,45)(H,38,46)(H,39,44)(H,41,42)(H2,47,48,49) RYYRPAZGAHMZGP-UHFFFAOYSA-N 50080834 CHEMBL409455::{4-[2-[2-(3-Amino-benzyloxycarbonylamino)-3-(4-phosphonooxy-phenyl)-propionylamino]-2-(1,2-dicarbamoyl-ethylcarbamoyl)-propyl]-phenyl}-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 198 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080834&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348451 103980958 CHEMBL409455 C03768 ZINC95613579 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141756 CC(Cc1ccc(O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C31H37N6O11P/c1-31(16-19-5-9-22(38)10-6-19,29(42)35-24(27(34)40)15-26(33)39)37-28(41)25(14-18-7-11-23(12-8-18)48-49(44,45)46)36-30(43)47-17-20-3-2-4-21(32)13-20/h2-13,24-25,38H,14-17,32H2,1H3,(H2,33,39)(H2,34,40)(H,35,42)(H,36,43)(H,37,41)(H2,44,45,46) HDNBNIBFHHHJHI-UHFFFAOYSA-N 50080835 CHEMBL333527::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-1-methyl-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 1098 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080835&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348452 103980959 CHEMBL333527 ZINC37099217 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141757 CC(Cc1ccc(O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C31H37N6O11P/c1-31(16-19-5-9-22(38)10-6-19,29(42)35-24(27(34)40)15-26(33)39)37-28(41)25(14-18-7-11-23(12-8-18)48-49(44,45)46)36-30(43)47-17-20-3-2-4-21(32)13-20/h2-13,24-25,38H,14-17,32H2,1H3,(H2,33,39)(H2,34,40)(H,35,42)(H,36,43)(H,37,41)(H2,44,45,46) HDNBNIBFHHHJHI-UHFFFAOYSA-N 50080835 CHEMBL333527::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-1-methyl-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 250 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080835&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348452 103980959 CHEMBL333527 ZINC37099217 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141758 CC(Cc1ccc(cc1)C(O)=O)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C32H37N6O12P/c1-32(16-19-5-9-21(10-6-19)29(42)43,30(44)36-24(27(35)40)15-26(34)39)38-28(41)25(14-18-7-11-23(12-8-18)50-51(46,47)48)37-31(45)49-17-20-3-2-4-22(33)13-20/h2-13,24-25H,14-17,33H2,1H3,(H2,34,39)(H2,35,40)(H,36,44)(H,37,45)(H,38,41)(H,42,43)(H2,46,47,48) ZSFMNJDMACNKQW-UHFFFAOYSA-N 50080836 4-[2-[2-(3-Amino-benzyloxycarbonylamino)-3-(4-phosphonooxy-phenyl)-propionylamino]-2-(1,2-dicarbamoyl-ethylcarbamoyl)-propyl]-benzoic acid::CHEMBL409262 Growth factor receptor-bound protein 2 Homo sapiens 153 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080836&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348450 103980960 CHEMBL409262 ZINC37099219 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141759 CC(Cc1ccc(cc1)C(O)=O)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O InChI=1S/C32H37N6O12P/c1-32(16-19-5-9-21(10-6-19)29(42)43,30(44)36-24(27(35)40)15-26(34)39)38-28(41)25(14-18-7-11-23(12-8-18)50-51(46,47)48)37-31(45)49-17-20-3-2-4-22(33)13-20/h2-13,24-25H,14-17,33H2,1H3,(H2,34,39)(H2,35,40)(H,36,44)(H,37,45)(H,38,41)(H,42,43)(H2,46,47,48) ZSFMNJDMACNKQW-UHFFFAOYSA-N 50080836 4-[2-[2-(3-Amino-benzyloxycarbonylamino)-3-(4-phosphonooxy-phenyl)-propionylamino]-2-(1,2-dicarbamoyl-ethylcarbamoyl)-propyl]-benzoic acid::CHEMBL409262 Growth factor receptor-bound protein 2 Homo sapiens 45 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080836&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348450 103980960 CHEMBL409262 ZINC37099219 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50141760 NC(=O)CC(NC(=O)C1(CCCCC1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42) XWNQRYAPQUFUMS-UHFFFAOYSA-N 50080831 CHEMBL434413::[1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 120 ChEMBL 10.1021/jm9911074 10.7270/Q2MW2GB6 10479306 Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080831&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44348294 103980955 CHEMBL434413 ZINC27202638 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144306 CC(=O)N[C@H](C(=O)NC1(CC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C18H24N5O9P/c1-9(24)21-14(10-2-4-11(5-3-10)32-33(29,30)31)16(27)23-18(6-7-18)17(28)22-12(15(20)26)8-13(19)25/h2-5,12,14H,6-8H2,1H3,(H2,19,25)(H2,20,26)(H,21,24)(H,22,28)(H,23,27)(H2,29,30,31)/t12-,14-/m0/s1 RXVBHAIEQMFQFF-JSGCOSHPSA-N 50082254 CHEMBL2370321::Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclopropylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 72500 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082254&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73354553 103982085 CHEMBL2370321 ZINC26735070 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144307 CC(=O)N[C@H](C(=O)NC1(CCCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C22H32N5O9P/c1-13(28)25-18(14-6-8-15(9-7-14)36-37(33,34)35)20(31)27-22(10-4-2-3-5-11-22)21(32)26-16(19(24)30)12-17(23)29/h6-9,16,18H,2-5,10-12H2,1H3,(H2,23,29)(H2,24,30)(H,25,28)(H,26,32)(H,27,31)(H2,33,34,35) APNLJGQOABCEJE-UHFFFAOYSA-N 50082255 CHEMBL3142743::Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cycloheptylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 1110 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082255&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 90663130 103982086 CHEMBL3142743CHEMBL98375 ZINC26739406 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144308 CC(=O)N[C@H](C(=O)NC1(CCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C20H28N5O9P/c1-11(26)23-16(12-4-6-13(7-5-12)34-35(31,32)33)18(29)25-20(8-2-3-9-20)19(30)24-14(17(22)28)10-15(21)27/h4-7,14,16H,2-3,8-10H2,1H3,(H2,21,27)(H2,22,28)(H,23,26)(H,24,30)(H,25,29)(H2,31,32,33) LQTBFYRJYPVRAW-UHFFFAOYSA-N 50082256 CHEMBL3142742::Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclopentylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 7900 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082256&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 90663129 103982087 CHEMBL3142742CHEMBL98768 ZINC26732144 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144309 CC(=O)N[C@H](C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C21H30N5O9P/c1-12(27)24-17(13-5-7-14(8-6-13)35-36(32,33)34)19(30)26-21(9-3-2-4-10-21)20(31)25-15(18(23)29)11-16(22)28/h5-8,15,17H,2-4,9-11H2,1H3,(H2,22,28)(H2,23,29)(H,24,27)(H,25,31)(H,26,30)(H2,32,33,34) RCDCXHOAJXNOGI-UHFFFAOYSA-N 50082257 CHEMBL3142740::Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 210 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082257&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 90663127 103982088 CHEMBL3142740CHEMBL99327 ZINC26741898 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144310 CC(=O)N[C@H](C(=O)NC1(CCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C19H26N5O9P/c1-10(25)22-15(11-3-5-12(6-4-11)33-34(30,31)32)17(28)24-19(7-2-8-19)18(29)23-13(16(21)27)9-14(20)26/h3-6,13,15H,2,7-9H2,1H3,(H2,20,26)(H2,21,27)(H,22,25)(H,23,29)(H,24,28)(H2,30,31,32)/t13-,15-/m0/s1 ODUSXUGDCFGWDV-ZFWWWQNUSA-N 50082258 CHEMBL2370326::Phosphoric acid mono-(4-{acetylamino-[1-(1,2-dicarbamoyl-ethylcarbamoyl)-cyclobutylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 18200 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082258&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73346986 103982089 CHEMBL2370326 ZINC26737183 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144311 CC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C16H22N5O9P/c1-8(22)20-14(9-2-4-10(5-3-9)30-31(27,28)29)16(26)19-7-13(24)21-11(15(18)25)6-12(17)23/h2-5,11,14H,6-7H2,1H3,(H2,17,23)(H2,18,25)(H,19,26)(H,20,22)(H,21,24)(H2,27,28,29)/t11-,14-/m0/s1 PMLNEEMPZWPWNJ-FZMZJTMJSA-N 50082259 CHEMBL2370323::Phosphoric acid mono-[4-(acetylamino-{[(1,2-dicarbamoyl-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 67000 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082259&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73350079 103982090 CHEMBL2370323 ZINC26734798 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50144312 CC(C)[C@H](NC(=O)[C@@H](NC(C)=O)c1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C19H28N5O9P/c1-9(2)15(18(28)23-13(17(21)27)8-14(20)26)24-19(29)16(22-10(3)25)11-4-6-12(7-5-11)33-34(30,31)32/h4-7,9,13,15-16H,8H2,1-3H3,(H2,20,26)(H2,21,27)(H,22,25)(H,23,28)(H,24,29)(H2,30,31,32)/t13-,15-,16-/m0/s1 DPSRVEKKGPROPW-BPUTZDHNSA-N 50082260 CHEMBL2370322::Phosphoric acid mono-(4-{acetylamino-[(S)-1-(1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-propylcarbamoyl]-methyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 4300 ChEMBL 10.1016/s0960-894x(99)00501-6 10.7270/Q2C24VN3 10571147 Garcia-Echeverria, C; Gay, B; Rahuel, J; Furet, P Novartis Pharma Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082260&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73346985 103982091 CHEMBL2370322 ZINC26742232 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152725 CC(=O)N[C@@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H45N5O9/c1-23(44)41-29(21-24-14-16-27(17-15-24)32(35(48)49)36(50)51)34(47)43-38(18-5-2-6-19-38)37(52)42-30(22-31(39)45)33(46)40-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30,32H,2,5-6,8,12,18-22H2,1H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,52)(H,43,47)(H,48,49)(H,50,51)/t29-,30-/m0/s1 ZNHFIPFVJSDHFT-KYJUHHDHSA-N 50085865 2-[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-malonic acid::CHEMBL355776 Growth factor receptor-bound protein 2 Homo sapiens 160 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9810437 103985275 CHEMBL355776 ZINC28000772 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152726 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O12/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)55-30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 DIULGUYADJZGME-NSOVKSMOSA-N 50085866 2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenoxy}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenoxy}-malonic acid::CHEMBL171244 Growth factor receptor-bound protein 2 Homo sapiens 1100 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085866&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11803277 103985276 CHEMBL171244 ZINC95606318 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152727 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 ZOJQPGFTWKKVQO-NSOVKSMOSA-N 50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150 Growth factor receptor-bound protein 2 Homo sapiens 70.0 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9896853 103985277 CHEMBL303150 ZINC95610086 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152728 CC(=O)N[C@@H](Cc1ccc(cc1)C(F)(C(O)=O)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H44FN5O9/c1-23(45)42-29(21-24-14-16-27(17-15-24)38(39,35(50)51)36(52)53)33(48)44-37(18-5-2-6-19-37)34(49)43-30(22-31(40)46)32(47)41-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,40,46)(H,41,47)(H,42,45)(H,43,49)(H,44,48)(H,50,51)(H,52,53)/t29-,30-/m0/s1 PBPYZTGBOYPNII-KYJUHHDHSA-N 50085868 2-[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-2-fluoro-malonic acid::CHEMBL443564 Growth factor receptor-bound protein 2 Homo sapiens 680.0 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085868&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11803070 103985278 CHEMBL443564 ZINC28012183 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152729 Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(=O)C(O)=O)ccc2c1 InChI=1S/C35H45N6O10P/c1-22-6-11-28-25(18-22)12-17-41(28)16-5-15-37-30(43)27(20-29(36)42)39-34(48)35(13-3-2-4-14-35)40-31(44)26(38-32(45)33(46)47)19-23-7-9-24(10-8-23)21-52(49,50)51/h6-12,17-18,26-27H,2-5,13-16,19-21H2,1H3,(H2,36,42)(H,37,43)(H,38,45)(H,39,48)(H,40,44)(H,46,47)(H2,49,50,51)/t26-,27-/m0/s1 FBOQMARWAPUCET-SVBPBHIXSA-N 50085869 CHEMBL367037::N-[1-(1-{2-Carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 2 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085869&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9853454 103985279 CHEMBL367037 ZINC28010547 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152730 CC(=O)N[C@@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H45N5O10/c1-23(44)41-29(21-24-14-16-27(17-15-24)53-32(35(48)49)36(50)51)34(47)43-38(18-5-2-6-19-38)37(52)42-30(22-31(39)45)33(46)40-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30,32H,2,5-6,8,12,18-22H2,1H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,52)(H,43,47)(H,48,49)(H,50,51)/t29-,30-/m0/s1 RPVSORRCJQCJIE-KYJUHHDHSA-N 50085870 2-[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-malonic acid::CHEMBL355701 Growth factor receptor-bound protein 2 Homo sapiens 2750 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085870&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10842644 103985280 CHEMBL355701 ZINC28003753 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152731 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O10/c38-30(43)21-29(32(46)39-19-7-11-25-10-6-9-24-8-2-3-12-27(24)25)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-26(16-14-23)52-22-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 OZMYXAMTIOVAPK-VMPREFPWSA-N 50085871 CHEMBL174418::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethoxy-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethoxy-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 19000 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085871&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383826 103985281 CHEMBL174418 ZINC28009363 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152732 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(F)(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H42FN5O11/c39-38(35(52)53,36(54)55)25-15-13-22(14-16-25)20-27(42-32(48)33(49)50)31(47)44-37(17-4-1-5-18-37)34(51)43-28(21-29(40)45)30(46)41-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24/h2-3,6,8-10,12-16,27-28H,1,4-5,7,11,17-21H2,(H2,40,45)(H,41,46)(H,42,48)(H,43,51)(H,44,47)(H,49,50)(H,52,53)(H,54,55)/t27-,28-/m0/s1 PQYZQUWBIUZVFZ-NSOVKSMOSA-N 50085872 2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-2-fluoro-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-2-fluoro-malonic acid::CHEMBL353708 Growth factor receptor-bound protein 2 Homo sapiens 170 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085872&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10652731 103985282 CHEMBL353708 ZINC95542408 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152733 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 50 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152734 CC(=O)N[C@@H](Cc1ccc(CC(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H45N5O7/c1-24(43)40-30(21-25-14-16-26(17-15-25)22-33(45)46)35(48)42-37(18-5-2-6-19-37)36(49)41-31(23-32(38)44)34(47)39-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,38,44)(H,39,47)(H,40,43)(H,41,49)(H,42,48)(H,45,46)/t30-,31-/m0/s1 MNNBOBOXKZOXSF-CONSDPRKSA-N 50085873 CHEMBL355777::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 6400 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085873&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383457 103985283 CHEMBL355777 C03768 ZINC28000778 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152735 CC(=O)N[C@@H](Cc1ccc(OCC(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H45N5O8/c1-24(43)40-30(21-25-14-16-28(17-15-25)50-23-33(45)46)35(48)42-37(18-5-2-6-19-37)36(49)41-31(22-32(38)44)34(47)39-20-8-12-27-11-7-10-26-9-3-4-13-29(26)27/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,38,44)(H,39,47)(H,40,43)(H,41,49)(H,42,48)(H,45,46)/t30-,31-/m0/s1 JDPYMLPVGSMNKO-CONSDPRKSA-N 50085875 CHEMBL172088::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenoxy]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 68000 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085875&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44384378 103985285 CHEMBL172088 ZINC28016752 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152736 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 InChI=1S/C35H47N6O8P/c1-23-7-12-30-27(19-23)13-18-41(30)17-6-16-37-32(44)29(21-31(36)43)39-34(46)35(14-4-3-5-15-35)40-33(45)28(38-24(2)42)20-25-8-10-26(11-9-25)22-50(47,48)49/h7-13,18-19,28-29H,3-6,14-17,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1 DLQYBJRFYUMKRJ-VMPREFPWSA-N 50073909 CHEMBL72036::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid::{4-[2-Acetylamino-2-(1-{2-carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 4 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073909&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10417376 103967193 CHEMBL72036 ZINC26376167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152737 CC(=O)N[C@@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 InChI=1S/C37H46N6O9/c1-22-7-12-29-26(19-22)13-18-43(29)17-6-16-39-32(46)28(21-30(38)45)41-36(52)37(14-4-3-5-15-37)42-33(47)27(40-23(2)44)20-24-8-10-25(11-9-24)31(34(48)49)35(50)51/h7-13,18-19,27-28,31H,3-6,14-17,20-21H2,1-2H3,(H2,38,45)(H,39,46)(H,40,44)(H,41,52)(H,42,47)(H,48,49)(H,50,51)/t27-,28-/m0/s1 JJOFUDMITTWTMS-NSOVKSMOSA-N 50085876 2-{4-[2-Acetylamino-2-(1-{2-carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-phenyl}-malonic acid::CHEMBL368263 Growth factor receptor-bound protein 2 Homo sapiens 12 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085876&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9961873 103985286 CHEMBL368263 ZINC28010541 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152738 Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(cc3)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)ccc2c1 InChI=1S/C37H44N6O11/c1-21-6-11-27-24(18-21)12-17-43(27)16-5-15-39-30(45)26(20-28(38)44)41-36(54)37(13-3-2-4-14-37)42-31(46)25(40-32(47)35(52)53)19-22-7-9-23(10-8-22)29(33(48)49)34(50)51/h6-12,17-18,25-26,29H,2-5,13-16,19-20H2,1H3,(H2,38,44)(H,39,45)(H,40,47)(H,41,54)(H,42,46)(H,48,49)(H,50,51)(H,52,53)/t25-,26-/m0/s1 BWMUTXRIOZYZEZ-UIOOFZCWSA-N 50085874 2-{4-[(S)-2-(1-{(S)-2-Carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-(1-{2-Carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL279961 Growth factor receptor-bound protein 2 Homo sapiens 8 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085874&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9810695 103985284 CHEMBL279961 ZINC95608452 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152739 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O9/c38-30(43)22-29(32(46)39-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-24(16-14-23)21-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 XYXSUXVWOJXCIE-VMPREFPWSA-N 50085877 CHEMBL355066::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 1000 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085877&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10032662 103985287 CHEMBL355066 C03768 ZINC27992388 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50152740 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H46N5O8P/c1-24(42)39-30(21-25-14-16-26(17-15-25)23-50(47,48)49)34(45)41-36(18-5-2-6-19-36)35(46)40-31(22-32(37)43)33(44)38-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,37,43)(H,38,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t30-,31-/m0/s1 MNFGRMAJNGDXMU-CONSDPRKSA-N 50072861 CHEMBL19417::[(S)-4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1021/jm9904248 10.7270/Q2WD3ZRD 10715157 Gao, Y; Luo, J; Yao, ZJ; Guo, R; Zou, H; Kelley, J; Voigt, JH; Yang, D; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072861&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10699955 103966452 CHEMBL19417 ZINC28225403 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50155196 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C40H62N11O17P/c1-18(2)31(38(61)45-23(11-12-28(41)53)34(57)48-26(40(63)64)16-30(43)55)51-36(59)25(15-29(42)54)47-39(62)32(19(3)4)50-35(58)24(14-20-7-9-21(10-8-20)68-69(65,66)67)46-37(60)27(17-52)49-33(56)22-6-5-13-44-22/h7-10,18-19,22-27,31-32,44,52H,5-6,11-17H2,1-4H3,(H2,41,53)(H2,42,54)(H2,43,55)(H,45,61)(H,46,60)(H,47,62)(H,48,57)(H,49,56)(H,50,58)(H,51,59)(H,63,64)(H2,65,66,67)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1 OWOWCUYLFWUPFH-FIOLWHMYSA-N 50087242 CHEMBL422705::Pro-Ser-pTyr-Val-Asn-Val-Gln-Asn Growth factor receptor-bound protein 2 Homo sapiens 18 ChEMBL 10.1016/s0960-894x(00)00077-9 10.7270/Q2B857BR 10762050 Liu, WQ; Vidal, M; Mathe, C; Perigaud, C; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087242&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44373900 103986314 CHEMBL422705 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50155197 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C41H62F2N11O16P/c1-18(2)31(38(64)48-23(11-12-28(44)56)34(60)51-26(40(66)67)16-30(46)58)54-36(62)25(15-29(45)57)50-39(65)32(19(3)4)53-35(61)24(14-20-7-9-21(10-8-20)41(42,43)71(68,69)70)49-37(63)27(17-55)52-33(59)22-6-5-13-47-22/h7-10,18-19,22-27,31-32,47,55H,5-6,11-17H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,48,64)(H,49,63)(H,50,65)(H,51,60)(H,52,59)(H,53,61)(H,54,62)(H,66,67)(H2,68,69,70)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1 LZDYQRUJXLVBFM-FIOLWHMYSA-N 50087243 CHEMBL436789::Pro-Ser-F2Pmp-Val-Asn-Val-Gln-Asn Growth factor receptor-bound protein 2 Homo sapiens 200 ChEMBL 10.1016/s0960-894x(00)00077-9 10.7270/Q2B857BR 10762050 Liu, WQ; Vidal, M; Mathe, C; Perigaud, C; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087243&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44373869 103986315 CHEMBL436789 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50155198 CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C44H62N9O13P/c1-24(2)36(43(61)49-32(23-35(45)55)41(59)51-37(25(3)4)44(62)53-20-9-13-33(53)38(46)56)50-40(58)31(22-28-15-17-29(18-16-28)66-67(63,64)65)47-39(57)30(21-27-11-7-6-8-12-27)48-42(60)34-14-10-19-52(34)26(5)54/h6-8,11-12,15-18,24-25,30-34,36-37H,9-10,13-14,19-23H2,1-5H3,(H2,45,55)(H2,46,56)(H,47,57)(H,48,60)(H,49,61)(H,50,58)(H,51,59)(H2,63,64,65)/t30-,31-,32-,33-,34-,36-,37-/m0/s1 FHTZBFQXLLXMBY-PLMFXFJRSA-N 50087244 Ac-Pro-Phe-pTyr-Val-Asn-Val-Pro-NH2::CHEMBL2371245 Growth factor receptor-bound protein 2 Homo sapiens 30 ChEMBL 10.1016/s0960-894x(00)00077-9 10.7270/Q2B857BR 10762050 Liu, WQ; Vidal, M; Mathe, C; Perigaud, C; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087244&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73347064 103986316 CHEMBL2371245 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50155199 CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C41H64N11O16P/c1-19(2)32(39(62)46-24(11-12-29(42)54)35(58)49-27(41(64)65)16-31(44)56)52-37(60)26(15-30(43)55)48-40(63)33(20(3)4)51-36(59)25(14-21-7-9-22(10-8-21)18-69(66,67)68)47-38(61)28(17-53)50-34(57)23-6-5-13-45-23/h7-10,19-20,23-28,32-33,45,53H,5-6,11-18H2,1-4H3,(H2,42,54)(H2,43,55)(H2,44,56)(H,46,62)(H,47,61)(H,48,63)(H,49,58)(H,50,57)(H,51,59)(H,52,60)(H,64,65)(H2,66,67,68)/t23-,24-,25-,26-,27-,28-,32-,33-/m0/s1 RSDGCDVVAVQOPH-TUQKNVKFSA-N 50087245 CHEMBL345170::Pro-Ser-Pmp-Val-Asn-Val-Gln-Asn Growth factor receptor-bound protein 2 Homo sapiens 260 ChEMBL 10.1016/s0960-894x(00)00077-9 10.7270/Q2B857BR 10762050 Liu, WQ; Vidal, M; Mathe, C; Perigaud, C; Garbay, C University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087245&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44373901 103986317 CHEMBL345170 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166754 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C26H39N4O7P/c1-17(31)28-22(15-18-9-11-19(12-10-18)16-38(35,36)37)24(33)30-26(13-5-2-6-14-26)25(34)29-21-8-4-3-7-20(21)23(27)32/h9-12,20-22H,2-8,13-16H2,1H3,(H2,27,32)(H,28,31)(H,29,34)(H,30,33)(H2,35,36,37)/t20-,21+,22-/m0/s1 HXDHXQMPLHBMEK-BDTNDASRSA-N 50093125 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-phosphonic acid::CHEMBL78242 Growth factor receptor-bound protein 2 Homo sapiens 700 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093125&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44315106 103991125 CHEMBL78242 ZINC26396323 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166755 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)C=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C27H41N4O7P/c1-18(33)29-23(15-19-9-11-20(12-10-19)16-39(37,38)17-32)25(35)31-27(13-5-2-6-14-27)26(36)30-22-8-4-3-7-21(22)24(28)34/h9-12,17,21-23,37-39H,2-8,13-16H2,1H3,(H2,28,34)(H,29,33)(H,30,36)(H,31,35)/t21-,22+,23-/m0/s1 UCEPIIWVYMBPRT-ZRBLBEILSA-N 50093128 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-hydroxymethyl-phosphinic acid::CHEMBL77253 Growth factor receptor-bound protein 2 Homo sapiens 7600 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093128&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 91931452 103991128 CHEMBL77253 ZINC26401628 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166756 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)C(=O)c2ccccc2)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C33H45N4O7P/c1-22(38)35-28(20-23-14-16-24(17-15-23)21-45(43,44)31(41)25-10-4-2-5-11-25)30(40)37-33(18-8-3-9-19-33)32(42)36-27-13-7-6-12-26(27)29(34)39/h2,4-5,10-11,14-17,26-28,43-45H,3,6-9,12-13,18-21H2,1H3,(H2,34,39)(H,35,38)(H,36,42)(H,37,40)/t26-,27+,28-/m0/s1 HDCIIGUMOFFPOY-IARZGTGTSA-N 50093126 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-(hydroxy-phenyl-methyl)-phosphinic acid::CHEMBL308867 Growth factor receptor-bound protein 2 Homo sapiens 530 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093126&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53870977 103991126 CHEMBL308867 ZINC26387227 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166757 CC(=O)N[C@@H](Cc1ccc(CP(O)(=O)Cc2ccccc2)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C33H45N4O6P/c1-23(38)35-29(20-24-14-16-26(17-15-24)22-44(42,43)21-25-10-4-2-5-11-25)31(40)37-33(18-8-3-9-19-33)32(41)36-28-13-7-6-12-27(28)30(34)39/h2,4-5,10-11,14-17,27-29H,3,6-9,12-13,18-22H2,1H3,(H2,34,39)(H,35,38)(H,36,41)(H,37,40)(H,42,43)/t27-,28+,29-/m0/s1 YHBRYVQHXNPTRB-NHKHRBQYSA-N 50093127 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-benzyl-phosphinic acid::CHEMBL78061 Growth factor receptor-bound protein 2 Homo sapiens 1200 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093127&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 12051496 103991127 CHEMBL78061 ZINC26396339 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166758 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)CC=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C28H43N4O7P/c1-19(34)30-24(17-20-9-11-21(12-10-20)18-40(38,39)16-15-33)26(36)32-28(13-5-2-6-14-28)27(37)31-23-8-4-3-7-22(23)25(29)35/h9-12,15,22-24,38-40H,2-8,13-14,16-18H2,1H3,(H2,29,35)(H,30,34)(H,31,37)(H,32,36)/t22-,23+,24-/m0/s1 JWYLYTODEVGDFL-VXNXHJTFSA-N 50093129 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-(2-hydroxy-ethyl)-phosphinic acid::CHEMBL429190 Growth factor receptor-bound protein 2 Homo sapiens 1600 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093129&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53979014 103991129 CHEMBL429190 ZINC26401636 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50166759 CC(=O)N[C@@H](Cc1ccc(CP(C)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H]1CCCC[C@@H]1C(N)=O InChI=1S/C27H41N4O6P/c1-18(32)29-23(16-19-10-12-20(13-11-19)17-38(2,36)37)25(34)31-27(14-6-3-7-15-27)26(35)30-22-9-5-4-8-21(22)24(28)33/h10-13,21-23H,3-9,14-17H2,1-2H3,(H2,28,33)(H,29,32)(H,30,35)(H,31,34)(H,36,37)/t21-,22+,23-/m0/s1 HQTDYCVNQZFEOV-ZRBLBEILSA-N 50093130 (4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cyclohexylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-methyl-phosphinic acid::CHEMBL419269 Growth factor receptor-bound protein 2 Homo sapiens 25500 ChEMBL 10.1016/s0960-894x(00)00475-3 10.7270/Q2SF2VDQ 11055351 Furet, P; Caravatti, G; Denholm, AA; Faessler, A; Fretz, H; Garcia-Echeverria, C; Gay, B; Irving, E; Press, NJ; Rahuel, J; Schoepfer, J; Walker, CV Novartis Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50093130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50093130&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44314998 103991130 CHEMBL419269 ZINC26403326 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50164888 CCC(C)\C=C(/C)\C=C\c1cc2=C(Cl)C(=O)[C@](C)(OC(C)=O)C(OC)=c2cn1 InChI=1S/C22H26ClNO4/c1-7-13(2)10-14(3)8-9-16-11-17-18(12-24-16)21(27-6)22(5,28-15(4)25)20(26)19(17)23/h8-13H,7H2,1-6H3/b9-8+,14-10+/t13?,22-/m0/s1 XEYGOCHZSYIFRN-BEFCGSBYSA-N 50241558 8-O-methylsclerotiorinamine::CHEMBL487793 Growth factor receptor-bound protein 2 Homo sapiens 5300 ChEMBL 10.1021/np0001169 10.7270/Q21R6Q7M 11000046 Nam, JY; Kim, HK; Kwon, JY; Han, MY; Son, KH; Lee, UC; Choi, JD; Kwon, BM Korea Research Institute of Bioscience & Biotechnology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241558&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9822467 104098809 CHEMBL487793 ZINC14693157 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158636 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H41F2N5O9/c38-37(39,35(52)53)25-15-13-22(14-16-25)20-27(42-32(48)33(49)50)31(47)44-36(17-4-1-5-18-36)34(51)43-28(21-29(40)45)30(46)41-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24/h2-3,6,8-10,12-16,27-28H,1,4-5,7,11,17-21H2,(H2,40,45)(H,41,46)(H,42,48)(H,43,51)(H,44,47)(H,49,50)(H,52,53)/t27-,28-/m0/s1 NLLHKIHZRXWCPN-NSOVKSMOSA-N 50088879 CHEMBL168417::{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-difluoro-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2000 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088879&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44382962 103987744 CHEMBL168417 ZINC27994105 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158637 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 ZOJQPGFTWKKVQO-NSOVKSMOSA-N 50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150 Growth factor receptor-bound protein 2 Homo sapiens 70.0 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9896853 103985277 CHEMBL303150 ZINC95610086 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158639 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(F)(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H42FN5O11/c39-38(35(52)53,36(54)55)25-15-13-22(14-16-25)20-27(42-32(48)33(49)50)31(47)44-37(17-4-1-5-18-37)34(51)43-28(21-29(40)45)30(46)41-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24/h2-3,6,8-10,12-16,27-28H,1,4-5,7,11,17-21H2,(H2,40,45)(H,41,46)(H,42,48)(H,43,51)(H,44,47)(H,49,50)(H,52,53)(H,54,55)/t27-,28-/m0/s1 PQYZQUWBIUZVFZ-NSOVKSMOSA-N 50085872 2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-2-fluoro-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-2-fluoro-malonic acid::CHEMBL353708 Growth factor receptor-bound protein 2 Homo sapiens 170 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085872&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10652731 103985282 CHEMBL353708 ZINC95542408 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158642 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O12/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)55-30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 DIULGUYADJZGME-NSOVKSMOSA-N 50085866 2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenoxy}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenoxy}-malonic acid::CHEMBL171244 Growth factor receptor-bound protein 2 Homo sapiens 1100 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085866&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11803277 103985276 CHEMBL171244 ZINC95606318 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158643 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O9/c38-30(43)22-29(32(46)39-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-24(16-14-23)21-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 XYXSUXVWOJXCIE-VMPREFPWSA-N 50085877 CHEMBL355066::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 600 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085877&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10032662 103985287 CHEMBL355066 C03768 ZINC27992388 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158646 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(C(O)=O)c(O)c1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H41N5O10/c37-29(43)20-27(30(44)38-17-7-11-23-10-6-9-22-8-2-3-12-24(22)23)40-35(51)36(15-4-1-5-16-36)41-31(45)26(39-32(46)34(49)50)18-21-13-14-25(33(47)48)28(42)19-21/h2-3,6,8-10,12-14,19,26-27,42H,1,4-5,7,11,15-18,20H2,(H2,37,43)(H,38,44)(H,39,46)(H,40,51)(H,41,45)(H,47,48)(H,49,50)/t26-,27-/m0/s1 WIQZIYIKHUYFHG-SVBPBHIXSA-N 50088883 4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-2-hydroxy-benzoic acid::CHEMBL433919 Growth factor receptor-bound protein 2 Homo sapiens 50000 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088883&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44382961 103987748 CHEMBL433919 ZINC27993478 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158649 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)c(c1)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O12/c39-30(44)20-28(32(47)40-17-7-11-24-10-6-9-23-8-2-3-12-25(23)24)42-37(54)38(15-4-1-5-16-38)43-33(48)27(41-34(49)36(52)53)19-22-13-14-29(55-21-31(45)46)26(18-22)35(50)51/h2-3,6,8-10,12-14,18,27-28H,1,4-5,7,11,15-17,19-21H2,(H2,39,44)(H,40,47)(H,41,49)(H,42,54)(H,43,48)(H,45,46)(H,50,51)(H,52,53)/t27-,28-/m0/s1 KXQNRHHJZUCNQZ-NSOVKSMOSA-N 50072868 5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-2-carboxymethoxy-benzoic acid::CHEMBL332671 Growth factor receptor-bound protein 2 Homo sapiens 1300 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072868&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10417671 103966459 CHEMBL332671 ZINC95611184 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158653 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O10/c38-30(43)21-29(32(46)39-19-7-11-25-10-6-9-24-8-2-3-12-27(24)25)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-26(16-14-23)52-22-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 OZMYXAMTIOVAPK-VMPREFPWSA-N 50085871 CHEMBL174418::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethoxy-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethoxy-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 15000 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085871&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383826 103985281 CHEMBL174418 ZINC28009363 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158654 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OCC(O)=O)c(OCC(O)=O)c1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C39H45N5O13/c40-31(45)20-28(34(50)41-17-7-11-25-10-6-9-24-8-2-3-12-26(24)25)43-38(55)39(15-4-1-5-16-39)44-35(51)27(42-36(52)37(53)54)18-23-13-14-29(56-21-32(46)47)30(19-23)57-22-33(48)49/h2-3,6,8-10,12-14,19,27-28H,1,4-5,7,11,15-18,20-22H2,(H2,40,45)(H,41,50)(H,42,52)(H,43,55)(H,44,51)(H,46,47)(H,48,49)(H,53,54)/t27-,28-/m0/s1 OKDSFGUXQASCLK-NSOVKSMOSA-N 50088889 CHEMBL355764::N-((S)-2-(3,4-Bis-carboxymethoxy-phenyl)-1-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088889&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383454 103987754 CHEMBL355764 ZINC95612338 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50158655 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(O)c(c1)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H41N5O10/c37-29(43)20-27(30(44)38-17-7-11-23-10-6-9-22-8-2-3-12-24(22)23)40-35(51)36(15-4-1-5-16-36)41-31(45)26(39-32(46)34(49)50)19-21-13-14-28(42)25(18-21)33(47)48/h2-3,6,8-10,12-14,18,26-27,42H,1,4-5,7,11,15-17,19-20H2,(H2,37,43)(H,38,44)(H,39,46)(H,40,51)(H,41,45)(H,47,48)(H,49,50)/t26-,27-/m0/s1 FRQDXWPIDLBMJU-SVBPBHIXSA-N 50088887 5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-2-hydroxy-benzoic acid::CHEMBL366735 Growth factor receptor-bound protein 2 Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(00)00124-4 10.7270/Q2W0956V 10853661 Gao, Y; Wu, L; Luo, JH; Guo, R; Yang, D; Zhang, ZY; Burke, TR National Cancer Institute-Bethesda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088887&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44384505 103987752 CHEMBL366735 ZINC28019910 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50184854 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(01)00316-x 10.7270/Q2BV7FW1 11459654 Gao, Y; Voigt, J; Wu, JX; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50184855 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)CCc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C34H43N4O7P/c35-30(39)22-29(32(41)36-21-7-11-27-10-6-9-26-8-2-3-12-28(26)27)37-33(42)34(19-4-1-5-20-34)38-31(40)18-17-24-13-15-25(16-14-24)23-46(43,44)45/h2-3,6,8-10,12-16,29H,1,4-5,7,11,17-23H2,(H2,35,39)(H,36,41)(H,37,42)(H,38,40)(H2,43,44,45)/t29-/m0/s1 RSAQUCMMMUZTEG-LJAQVGFWSA-N 50102026 CHEMBL292883::[4-(2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 2000 ChEMBL 10.1016/s0960-894x(01)00316-x 10.7270/Q2BV7FW1 11459654 Gao, Y; Voigt, J; Wu, JX; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102026&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 12149268 103998587 CHEMBL292883 ZINC29552798 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50184856 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1016/s0960-894x(01)00316-x 10.7270/Q2BV7FW1 11459654 Gao, Y; Voigt, J; Wu, JX; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50184857 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H46N5O8P/c1-24(42)39-30(21-25-14-16-26(17-15-25)23-50(47,48)49)34(45)41-36(18-5-2-6-19-36)35(46)40-31(22-32(37)43)33(44)38-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,37,43)(H,38,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t30-,31-/m0/s1 MNFGRMAJNGDXMU-CONSDPRKSA-N 50072861 CHEMBL19417::[(S)-4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 55.0 ChEMBL 10.1016/s0960-894x(01)00316-x 10.7270/Q2BV7FW1 11459654 Gao, Y; Voigt, J; Wu, JX; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072861&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10699955 103966452 CHEMBL19417 ZINC28225403 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179123 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccc(O)cc12 InChI=1S/C36H46N5O9P/c1-23(42)39-30(19-24-10-12-25(13-11-24)22-51(48,49)50)34(46)41-36(16-3-2-4-17-36)35(47)40-31(21-32(37)44)33(45)38-18-6-9-26-7-5-8-27-14-15-28(43)20-29(26)27/h5,7-8,10-15,20,30-31,43H,2-4,6,9,16-19,21-22H2,1H3,(H2,37,44)(H,38,45)(H,39,42)(H,40,47)(H,41,46)(H2,48,49,50)/t30-,31-/m0/s1 RDKFVKFIXDCKSO-CONSDPRKSA-N 50099448 CHEMBL276300::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(7-hydroxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 25 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099448&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44272867 103996321 CHEMBL276300 ZINC28225339 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179124 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2cc(O)ccc12 InChI=1S/C36H46N5O9P/c1-23(42)39-30(19-24-10-12-25(13-11-24)22-51(48,49)50)34(46)41-36(16-3-2-4-17-36)35(47)40-31(21-32(37)44)33(45)38-18-6-9-26-7-5-8-27-20-28(43)14-15-29(26)27/h5,7-8,10-15,20,30-31,43H,2-4,6,9,16-19,21-22H2,1H3,(H2,37,44)(H,38,45)(H,39,42)(H,40,47)(H,41,46)(H2,48,49,50)/t30-,31-/m0/s1 PFCILBBKLLZRAF-CONSDPRKSA-N 50099447 CHEMBL278567::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(6-hydroxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 43 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099447&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44272866 103996320 CHEMBL278567 ZINC28227136 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179125 COc1ccc2c(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)cccc2c1 InChI=1S/C37H48N5O9P/c1-24(43)40-31(20-25-11-13-26(14-12-25)23-52(48,49)50)35(46)42-37(17-4-3-5-18-37)36(47)41-32(22-33(38)44)34(45)39-19-7-10-27-8-6-9-28-21-29(51-2)15-16-30(27)28/h6,8-9,11-16,21,31-32H,3-5,7,10,17-20,22-23H2,1-2H3,(H2,38,44)(H,39,45)(H,40,43)(H,41,47)(H,42,46)(H2,48,49,50)/t31-,32-/m0/s1 KROYSCLPCFKFPY-ACHIHNKUSA-N 50099449 CHEMBL281577::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(6-methoxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 130 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099449&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44272746 103996322 CHEMBL281577 ZINC28224533 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179126 Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(cc3)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)ccc2c1 InChI=1S/C37H44N6O11/c1-21-6-11-27-24(18-21)12-17-43(27)16-5-15-39-30(45)26(20-28(38)44)41-36(54)37(13-3-2-4-14-37)42-31(46)25(40-32(47)35(52)53)19-22-7-9-23(10-8-22)29(33(48)49)34(50)51/h6-12,17-18,25-26,29H,2-5,13-16,19-20H2,1H3,(H2,38,44)(H,39,45)(H,40,47)(H,41,54)(H,42,46)(H,48,49)(H,50,51)(H,52,53)/t25-,26-/m0/s1 BWMUTXRIOZYZEZ-UIOOFZCWSA-N 50085874 2-{4-[(S)-2-(1-{(S)-2-Carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-(1-{2-Carbamoyl-1-[3-(5-methyl-indol-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL279961 Growth factor receptor-bound protein 2 Homo sapiens 8 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085874&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9810695 103985284 CHEMBL279961 ZINC95608452 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179127 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H46N5O8P/c1-24(42)39-30(21-25-14-16-26(17-15-25)23-50(47,48)49)34(45)41-36(18-5-2-6-19-36)35(46)40-31(22-32(37)43)33(44)38-20-8-12-28-11-7-10-27-9-3-4-13-29(27)28/h3-4,7,9-11,13-17,30-31H,2,5-6,8,12,18-23H2,1H3,(H2,37,43)(H,38,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t30-,31-/m0/s1 MNFGRMAJNGDXMU-CONSDPRKSA-N 50072861 CHEMBL19417::[(S)-4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-((S)-2-Acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid::[4-(2-Acetylamino-2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 43 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072861&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10699955 103966452 CHEMBL19417 ZINC28225403 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179128 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1ccc2cccc(O)c2c1 InChI=1S/C36H46N5O9P/c1-23(42)39-29(20-25-10-12-26(13-11-25)22-51(48,49)50)34(46)41-36(16-3-2-4-17-36)35(47)40-30(21-32(37)44)33(45)38-18-6-7-24-14-15-27-8-5-9-31(43)28(27)19-24/h5,8-15,19,29-30,43H,2-4,6-7,16-18,20-22H2,1H3,(H2,37,44)(H,38,45)(H,39,42)(H,40,47)(H,41,46)(H2,48,49,50)/t29-,30-/m0/s1 MMVMGVXKNYWPLG-KYJUHHDHSA-N 50099450 CHEMBL19378::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(8-hydroxy-naphthalen-2-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 11 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099450&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10259330 103996323 CHEMBL19378 ZINC28224238 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179129 CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1c(O)ccc2ccccc12 InChI=1S/C36H46N5O9P/c1-23(42)39-29(20-24-11-13-25(14-12-24)22-51(48,49)50)34(46)41-36(17-5-2-6-18-36)35(47)40-30(21-32(37)44)33(45)38-19-7-10-28-27-9-4-3-8-26(27)15-16-31(28)43/h3-4,8-9,11-16,29-30,43H,2,5-7,10,17-22H2,1H3,(H2,37,44)(H,38,45)(H,39,42)(H,40,47)(H,41,46)(H2,48,49,50)/t29-,30-/m0/s1 DXUDLEHAROCUHM-KYJUHHDHSA-N 50099452 CGP-78850::CHEMBL276046::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(2-hydroxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 43 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099452&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9940118 103996325 CHEMBL276046 ZINC28225027 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50179130 COc1cc2cccc(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)c2cc1OC InChI=1S/C38H50N5O10P/c1-24(44)41-30(19-25-12-14-26(15-13-25)23-54(49,50)51)36(47)43-38(16-5-4-6-17-38)37(48)42-31(22-34(39)45)35(46)40-18-8-11-27-9-7-10-28-20-32(52-2)33(53-3)21-29(27)28/h7,9-10,12-15,20-21,30-31H,4-6,8,11,16-19,22-23H2,1-3H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,48)(H,43,47)(H2,49,50,51)/t30-,31-/m0/s1 SLXHIXKJEPUSKD-CONSDPRKSA-N 50099451 CHEMBL19214::{4-[(S)-2-Acetylamino-2-(1-{(S)-2-carbamoyl-1-[3-(6,7-dimethoxy-naphthalen-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-ethyl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 84 ChEMBL 10.1016/s0960-894x(01)00173-1 10.7270/Q2G1603X 11354377 Schoepfer, J; Gay, B; End, N; Muller, E; Scheffel, G; Caravatti, G; Furet, P Novartis Pharma AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099451&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44272745 103996324 CHEMBL19214 ZINC95606305 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50214402 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)N=[N+]=[N-])C(=O)NCCCc1cccc2ccccc12 InChI=1S/C34H42N7O7P/c35-30(42)21-28(31(43)37-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)38-33(45)34(17-4-1-5-18-34)39-32(44)29(40-41-36)20-23-13-15-24(16-14-23)22-49(46,47)48/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,35,42)(H,37,43)(H,38,45)(H,39,44)(H2,46,47,48)/t28-,29-/m0/s1 OMNUIMNPAZIAAP-VMPREFPWSA-N 50118686 CHEMBL323505::[(S)-3-(2-Azido-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 5000 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118686&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44326935 104011950 CHEMBL323505 ZINC36761376 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50214403 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H45N4O9P/c37-31(41)22-30(34(45)38-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27)39-35(46)36(17-4-1-5-18-36)40-33(44)28(21-32(42)43)20-24-13-15-25(16-14-24)23-50(47,48)49/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1 AYRBFDFQLSQIBI-DGPALRBDSA-N 50118687 (R)-N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-(4-phosphonomethyl-benzyl)-succinamic acid::CHEMBL93367::N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-((R)-3-phosphonomethyl-benzyl)-succinamic acid Growth factor receptor-bound protein 2 Homo sapiens 8 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118687&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987336 104011951 CHEMBL93367 ZINC26663353 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50214404 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 3000 ChEMBL 10.1016/s0960-894x(02)00527-9 10.7270/Q23R0S6B 12217375 Wei, CQ; Li, B; Guo, R; Yang, D; Burke, TR National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50221216 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 0.075 ChEMBL 10.1021/jm1012374 10.7270/Q28C9XDV 21381769 Marsault, E; Peterson, ML Universite£ de Sherbrooke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50221266 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens >10000 ChEMBL 10.1021/jm1012374 10.7270/Q28C9XDV 21381769 Marsault, E; Peterson, ML Universite£ de Sherbrooke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50222462 CC1(C)NC(=O)C[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C34H43N4O7P/c1-34(2)33(42)37-29(19-30(35)39)32(41)36-20-23(17-27-11-6-9-25-8-3-4-12-28(25)27)7-5-10-26(18-31(40)38-34)24-15-13-22(14-16-24)21-46(43,44)45/h3-5,8-10,12-16,23,26,29H,6-7,11,17-21H2,1-2H3,(H2,35,39)(H,36,41)(H,37,42)(H,38,40)(H2,43,44,45)/b10-5+/t23-,26-,29-/m0/s1 FKJYTGUFQKOJNO-CLPFAVJESA-N 50122793 CHEMBL313407::{4-[3-Carbamoylmethyl-14-(2,3-dihydro-naphthalen-1-ylmethyl)-6,6-dimethyl-2,5,8-trioxo-1,4,7triaza-cyclopentadec-11-en-10-yl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 700 ChEMBL 10.1021/jm0203635 10.7270/Q2RR1XMN 12519063 Wei, CQ; Gao, Y; Lee, K; Guo, R; Li, B; Zhang, M; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122793&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44319042 104015413 CHEMBL313407 ZINC26568123 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50222463 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](C\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C38H47N4O7P/c39-34(43)23-33-36(45)40-24-27(21-31-13-8-12-29-10-4-5-14-32(29)31)9-2-3-11-30(28-17-15-26(16-18-28)25-50(47,48)49)22-35(44)42-38(37(46)41-33)19-6-1-7-20-38/h2-5,8,10,12-18,27,30,33H,1,6-7,9,11,19-25H2,(H2,39,43)(H,40,45)(H,41,46)(H,42,44)(H2,47,48,49)/b3-2+/t27-,30-,33-/m0/s1 DUQLHBZZOWMHBA-BINFHYMYSA-N 50122795 CHEMBL315337::[4-(19-Carbamoylmethyl-15-naphthalen-1-ylmethyl-8,18,21-trioxo-7,17,20-triaza-spiro[5.15]henicos-12-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >10000 ChEMBL 10.1021/jm0203635 10.7270/Q2RR1XMN 12519063 Wei, CQ; Gao, Y; Lee, K; Guo, R; Li, B; Zhang, M; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122795&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10974527 104015414 CHEMBL315337 ZINC26568888 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50222464 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C39H49N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6,9-10,12-17,26,31-33H,1,4-5,7-8,11,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1 SZBXCUMMOMSDKH-FETINEJHSA-N 50122796 CHEMBL84798::[18-Carbamoylmethyl-14-(2,3-dihydro-naphthalen-1-ylmethyl)-8,17,20-trioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2 ChEMBL 10.1021/jm0203635 10.7270/Q2RR1XMN 12519063 Wei, CQ; Gao, Y; Lee, K; Guo, R; Li, B; Zhang, M; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122796&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44319025 104015415 CHEMBL84798 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50222465 CC1(C)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C36H45N4O9P/c1-36(2)35(46)39-30(19-31(37)41)34(45)38-20-23(17-26-10-6-9-24-8-3-4-11-27(24)26)7-5-12-28(29(18-32(42)43)33(44)40-36)25-15-13-22(14-16-25)21-50(47,48)49/h3-5,8-9,11-16,23,28-30H,6-7,10,17-21H2,1-2H3,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/b12-5+/t23-,28+,29-,30-/m0/s1 ZAVMSMAYSMBPEE-OYFLRRISSA-N 50122792 CHEMBL312875::[3-Carbamoylmethyl-14-(2,3-dihydro-naphthalen-1-ylmethyl)-6,6-dimethyl-2,5,8-trioxo-10-(4-phosphonomethyl-phenyl)-1,4,7triaza-cyclopentadec-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 8 ChEMBL 10.1021/jm0203635 10.7270/Q2RR1XMN 12519063 Wei, CQ; Gao, Y; Lee, K; Guo, R; Li, B; Zhang, M; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122792&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44319337 104015412 CHEMBL312875 ZINC26508770 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50222466 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H47N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6,9-11,13-17,26,29,32H,1,4-5,7-8,12,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 BTUVYXNBILEQJL-GZNVFMSSSA-N 50122797 CHEMBL406148::i{4-[18-Carbamoylmethyl-14-(2,3-dihydro-naphthalen-1-ylmethyl)-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl]-benzyl}-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1021/jm0203635 10.7270/Q2RR1XMN 12519063 Wei, CQ; Gao, Y; Lee, K; Guo, R; Li, B; Zhang, M; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122797&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44319336 104015416 CHEMBL406148 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225232 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)CCNC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C53H77N12O19PS2/c1-27(2)20-35-49(76)62-36(22-30-8-12-32(13-9-30)84-85(81,82)83)50(77)60-33(14-15-44(71)72)47(74)63-38(23-40(54)67)52(79)65-45(28(3)4)53(80)57-24-42(69)58-34(17-19-86-5)48(75)61-37(21-29-6-10-31(66)11-7-29)51(78)64-39(46(55)73)25-87-26-43(70)56-18-16-41(68)59-35/h6-13,27-28,33-39,45,66H,14-26H2,1-5H3,(H2,54,67)(H2,55,73)(H,56,70)(H,57,80)(H,58,69)(H,59,68)(H,60,77)(H,61,75)(H,62,76)(H,63,74)(H,64,78)(H,65,79)(H,71,72)(H2,81,82,83)/t33-,34-,35-,36-,37-,38-,39-,45-/m0/s1 OTBBFDYLSIHCEP-KZLGSIOZSA-N 50124291 3-[17-carbamoyl-32-carbamoylmethyl-20-(4-hydroxybenzyl)-7-isobutyl-29-isopropyl-4-(4-phosphonooxybenzyl)-23-(2-methylsulfanylethyl)-3,6,9,13,19,22,25,28,31,34-decaoxo-15-thia-2,5,8,12,18,21,24,27,30,33-decaazacyclotetratriacontanyl]propanoic acid::CHEMBL216415 Growth factor receptor-bound protein 2 Homo sapiens 8.3 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124291&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44382782 104016628 CHEMBL216415 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225233 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H79N12O21PS2/c1-27(2)20-36-51(80)64-37(22-30-8-12-32(13-9-30)88-89(85,86)87)52(81)61-34(15-17-45(74)75)49(78)65-39(23-41(56)69)54(83)67-46(28(3)4)55(84)58-24-42(70)59-35(18-19-90-5)50(79)63-38(21-29-6-10-31(68)11-7-29)53(82)66-40(47(57)76)25-91-26-43(71)60-33(48(77)62-36)14-16-44(72)73/h6-13,27-28,33-40,46,68H,14-26H2,1-5H3,(H2,56,69)(H2,57,76)(H,58,84)(H,59,70)(H,60,71)(H,61,81)(H,62,77)(H,63,79)(H,64,80)(H,65,78)(H,66,82)(H,67,83)(H,72,73)(H,74,75)(H2,85,86,87)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 LQKBCUCHZJQOJO-AGEHIQCHSA-N 50124292 3-[28-(4-phosphonooxy-benzyl)-7-carbamoyl-22-carbamoylmethyl-25-(2-carboxyethyl)-10-(4-hydroxybenzyl)-31-isobutyl-19-isopropyl-13-(2-methylsulfanylethyl)-3,9,12,15,18,21,24,27,30,33-decaoxo-5-thia-2,8,11,14,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL264809 Growth factor receptor-bound protein 2 Homo sapiens 137 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124292&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44382123 104016629 CHEMBL264809 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225234 CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C55H81N12O19PS/c1-27(2)19-35-49(77)63-36(21-31-11-15-33(16-12-31)86-87(83,84)85)50(78)61-34(17-18-44(72)73)48(76)65-38(22-41(56)69)52(80)67-45(28(3)4)54(82)58-24-42(70)60-39(23-55(6,7)8)53(81)64-37(20-30-9-13-32(68)14-10-30)51(79)66-40(46(57)74)25-88-26-43(71)59-29(5)47(75)62-35/h9-16,27-29,34-40,45,68H,17-26H2,1-8H3,(H2,56,69)(H2,57,74)(H,58,82)(H,59,71)(H,60,70)(H,61,78)(H,62,75)(H,63,77)(H,64,81)(H,65,76)(H,66,79)(H,67,80)(H,72,73)(H2,83,84,85)/t29-,34-,35-,36-,37-,38-,39-,40-,45-/m0/s1 IQGILYWVYZYTCX-OVKCSXIMSA-N 50124294 3-[4-(4-phosphonooxybenzyl)-16-carbamoyl-31-carbamoylmethyl-19-(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-10-methyl-22-neopentyl-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL407099 Growth factor receptor-bound protein 2 Homo sapiens 15 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124294&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383414 104016631 CHEMBL407099 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225235 CC(C)C[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C59H87N12O17PS/c1-32(2)24-38-50(77)65-40(26-35-15-19-37(20-16-35)88-89(85,86)87)54(81)70-59(21-9-8-10-22-59)57(84)68-41(27-45(60)73)52(79)69-48(33(3)4)56(83)62-29-46(74)63-42(28-58(5,6)7)53(80)64-39(25-34-13-17-36(72)18-14-34)51(78)67-43(49(61)76)30-90-31-47(75)71-23-11-12-44(71)55(82)66-38/h13-20,32-33,38-44,48,72H,8-12,21-31H2,1-7H3,(H2,60,73)(H2,61,76)(H,62,83)(H,63,74)(H,64,80)(H,65,77)(H,66,82)(H,67,78)(H,68,84)(H,69,79)(H,70,81)(H2,85,86,87)/t38-,39-,40-,41-,42-,43-,44-,48-/m0/s1 OWBXQNJYCXJMTB-WETWEQLNSA-N 50124293 2-[6'-(4-phosphonooxybenzyl)-27'-carbamoyl-24'-(4-hydroxybenzyl)-3'-isobutyl-21'-neopentyl-15'-isopropyl-1',4',7',10',13',16',19',22',25',31'-decaoxospiro[cyclohexane-1,9'-perhydropyrrolo[1,2-d][1,4,7,10,13,16,19,22,25,28,31]thiadecaazacyclotritriacontine]-12-yl]acetamide::CHEMBL2371617 Growth factor receptor-bound protein 2 Homo sapiens 7.7 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124293&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73347102 104016630 CHEMBL2371617 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225236 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)CCNC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H81N12O17PS2/c1-30(2)23-37-49(75)63-39(25-33-11-15-35(16-12-33)84-85(81,82)83)52(78)67-55(19-7-6-8-20-55)54(80)65-40(26-42(56)69)51(77)66-46(31(3)4)53(79)59-27-44(71)60-36(18-22-86-5)48(74)62-38(24-32-9-13-34(68)14-10-32)50(76)64-41(47(57)73)28-87-29-45(72)58-21-17-43(70)61-37/h9-16,30-31,36-41,46,68H,6-8,17-29H2,1-5H3,(H2,56,69)(H2,57,73)(H,58,72)(H,59,79)(H,60,71)(H,61,70)(H,62,74)(H,63,75)(H,64,76)(H,65,80)(H,66,77)(H,67,78)(H2,81,82,83)/t36-,37-,38-,39-,40-,41-,46-/m0/s1 IIJUTELNUBJEAD-VPEJRRDMSA-N 50124295 2-[9-(4-phosphonooxybenzyl)-22-carbamoyl-25-(4-hydroxybenzyl)-12-isobutyl-34-isopropyl-28-(2-methylsulfanylethyl)-8,11,14,18,24,27,30,33,36,39-decaoxo-20-thia-7,10,13,17,23,26,29,32,35,38-decaazaspiro[5.33]nonatriacont-37-yl]acetamide::CHEMBL406825 Growth factor receptor-bound protein 2 Homo sapiens 21 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124295&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383634 104016632 CHEMBL406825 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225237 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CSCC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C54H79N12O19PS2/c1-27(2)21-37-50(77)64-39(23-31-9-13-33(14-10-31)85-86(82,83)84)52(79)61-35(15-16-44(71)72)48(75)65-40(24-41(55)68)53(80)66-45(28(3)4)54(81)57-25-42(69)59-36(17-19-87-6)49(76)63-38(22-30-7-11-32(67)12-8-30)51(78)60-34(46(56)73)18-20-88-26-43(70)58-29(5)47(74)62-37/h7-14,27-29,34-40,45,67H,15-26H2,1-6H3,(H2,55,68)(H2,56,73)(H,57,81)(H,58,70)(H,59,69)(H,60,78)(H,61,79)(H,62,74)(H,63,76)(H,64,77)(H,65,75)(H,66,80)(H,71,72)(H2,82,83,84)/t29-,34-,35-,36-,37-,38-,39-,40-,45-/m0/s1 KFDLTASOKXPTHK-OVKCSXIMSA-N 50124297 3-[4-(4-phosphonooxybenzyl)-17-carbamoyl-32-carbamoylmethyl-20-(4-hydroxybenzyl)-7-isobutyl-29-isopropyl-10-methyl-23-(2-methylsulfanylethyl)-3,6,9,12,19,22,25,28,31,34-decaoxo-14-thia-2,5,8,11,18,21,24,27,30,33-decaazacyclotetratriacontanyl]propanoic acid::CHEMBL2371606 Growth factor receptor-bound protein 2 Homo sapiens 55 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124297&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73347100 104016634 CHEMBL2371606 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225238 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC1=O)C(N)=O InChI=1S/C60H83N12O17PS/c1-33(2)49-57(84)63-30-47(75)65-44(29-59(4,5)6)55(82)67-41(26-36-15-19-38(73)20-16-36)53(80)69-45(50(62)77)31-91-32-48(76)64-34(3)51(78)66-40(25-35-13-9-7-10-14-35)52(79)68-42(27-37-17-21-39(22-18-37)89-90(86,87)88)56(83)72-60(23-11-8-12-24-60)58(85)70-43(28-46(61)74)54(81)71-49/h7,9-10,13-22,33-34,40-45,49,73H,8,11-12,23-32H2,1-6H3,(H2,61,74)(H2,62,77)(H,63,84)(H,64,76)(H,65,75)(H,66,78)(H,67,82)(H,68,79)(H,69,80)(H,70,85)(H,71,81)(H,72,83)(H2,86,87,88)/t34-,40-,41-,42-,43-,44-,45-,49-/m0/s1 DFJBSYSXSLQESE-YECLUHMASA-N 50124296 12-benzyl-36-carbamoylmethyl-9-(4-phosphonooxybenzyl)-24-(4-hydroxybenzyl)-33-isopropyl-15-methyl-27-neopentyl-8,11,14,17,23,26,29,32,35,38-decaoxo-19-thia-7,10,13,16,22,25,28,31,34,37-decaazaspiro[5.32]octatriacontane-21-carboxamide::CHEMBL439878 Growth factor receptor-bound protein 2 Homo sapiens 1.7 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124296&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383412 104016633 CHEMBL439878 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225239 CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C53H77N12O17PS/c1-27(2)20-35-47(73)61-37(22-32-12-16-34(17-13-32)82-83(79,80)81)50(76)65-53(18-8-7-9-19-53)52(78)63-38(23-40(54)67)49(75)64-43(28(3)4)51(77)56-24-41(68)57-29(5)45(71)60-36(21-31-10-14-33(66)15-11-31)48(74)62-39(44(55)70)25-84-26-42(69)58-30(6)46(72)59-35/h10-17,27-30,35-39,43,66H,7-9,18-26H2,1-6H3,(H2,54,67)(H2,55,70)(H,56,77)(H,57,68)(H,58,69)(H,59,72)(H,60,71)(H,61,73)(H,62,74)(H,63,78)(H,64,75)(H,65,76)(H2,79,80,81)/t29-,30-,35-,36-,37-,38-,39-,43-/m0/s1 PSBVNCFXVBAVPK-LGJWLMJRSA-N 50124298 2-[9-(4-phosphonooxybenzyl)-21-carbamoyl-24-(4-hydroxybenzyl)-12-isobutyl-33-isopropyl-15,27-dimethyl-8,11,14,17,23,26,29,32,35,38-decaoxo-19-thia-7,10,13,16,22,25,28,31,34,37-decaazaspiro[5.32]octatriacont-36-yl]acetamide::CHEMBL2371623 Growth factor receptor-bound protein 2 Homo sapiens 13 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124298&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73356230 104016635 CHEMBL2371623 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225240 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C53H77N12O19PS2/c1-26(2)19-35-49(76)62-36(21-30-9-13-32(14-10-30)84-85(81,82)83)50(77)59-33(15-16-43(70)71)47(74)63-38(22-40(54)67)52(79)65-44(27(3)4)53(80)56-23-41(68)58-34(17-18-86-6)48(75)61-37(20-29-7-11-31(66)12-8-29)51(78)64-39(45(55)72)24-87-25-42(69)57-28(5)46(73)60-35/h7-14,26-28,33-39,44,66H,15-25H2,1-6H3,(H2,54,67)(H2,55,72)(H,56,80)(H,57,69)(H,58,68)(H,59,77)(H,60,73)(H,61,75)(H,62,76)(H,63,74)(H,64,78)(H,65,79)(H,70,71)(H2,81,82,83)/t28-,33-,34-,35-,36-,37-,38-,39-,44-/m0/s1 DPHPUTJXYPTOLJ-TWDLZMNVSA-N 50124299 3-[4-(4-phosphonooxybenzyl)-16-carbamoyl-31-carbamoylmethyl-19-(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-10-methyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL2371601 Growth factor receptor-bound protein 2 Homo sapiens 25 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124299&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73356227 104016636 CHEMBL2371601 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225241 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C52H75N12O19PS2/c1-26(2)18-34-48(75)61-35(20-29-8-12-31(13-9-29)83-84(80,81)82)49(76)59-32(14-15-43(70)71)46(73)62-37(21-39(53)66)51(78)64-44(27(3)4)52(79)56-23-41(68)57-33(16-17-85-5)47(74)60-36(19-28-6-10-30(65)11-7-28)50(77)63-38(45(54)72)24-86-25-42(69)55-22-40(67)58-34/h6-13,26-27,32-38,44,65H,14-25H2,1-5H3,(H2,53,66)(H2,54,72)(H,55,69)(H,56,79)(H,57,68)(H,58,67)(H,59,76)(H,60,74)(H,61,75)(H,62,73)(H,63,77)(H,64,78)(H,70,71)(H2,80,81,82)/t32-,33-,34-,35-,36-,37-,38-,44-/m0/s1 OBFREQQTUAVYFD-KKMVKRJBSA-N 50124300 3-[4-(4-phosphonooxybenzyl)-16-carbamoyl-31-carbamoylmethyl-19-(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL408163 Growth factor receptor-bound protein 2 Homo sapiens 32 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124300&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44382291 104016637 CHEMBL408163 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225242 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H81N12O17PS2/c1-29(2)22-37-49(75)63-39(24-33-12-16-35(17-13-33)84-85(81,82)83)52(78)67-55(19-8-7-9-20-55)54(80)65-40(25-42(56)69)51(77)66-45(30(3)4)53(79)58-26-43(70)60-36(18-21-86-6)48(74)62-38(23-32-10-14-34(68)15-11-32)50(76)64-41(46(57)72)27-87-28-44(71)59-31(5)47(73)61-37/h10-17,29-31,36-41,45,68H,7-9,18-28H2,1-6H3,(H2,56,69)(H2,57,72)(H,58,79)(H,59,71)(H,60,70)(H,61,73)(H,62,74)(H,63,75)(H,64,76)(H,65,80)(H,66,77)(H,67,78)(H2,81,82,83)/t31-,36-,37-,38-,39-,40-,41-,45-/m0/s1 XZUQZUIOFJUTIH-LRGYJGTCSA-N 50124301 2-[9-(4-phosphonooxybenzyl)-21-carbamoyl-24-(4-hydroxybenzyl)-12-isobutyl-33-isopropyl-15-methyl-27-(2-methylsulfanylethyl)-8,11,14,17,23,26,29,32,35,38-decaoxo-19-thia-7,10,13,16,22,25,28,31,34,37-decaazaspiro[5.32]octatriacont-36-yl]acetamide::CHEMBL2371612 Growth factor receptor-bound protein 2 Homo sapiens 3.8 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124301&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73354680 104016638 CHEMBL2371612 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225243 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CCCN2C(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H79N12O19PS2/c1-28(2)21-36-50(77)62-37(23-31-10-14-33(15-11-31)86-87(83,84)85)51(78)60-34(16-17-45(72)73)48(75)63-39(24-42(56)69)53(80)66-46(29(3)4)55(82)58-25-43(70)59-35(18-20-88-5)49(76)61-38(22-30-8-12-32(68)13-9-30)52(79)65-40(47(57)74)26-89-27-44(71)67-19-6-7-41(67)54(81)64-36/h8-15,28-29,34-41,46,68H,6-7,16-27H2,1-5H3,(H2,56,69)(H2,57,74)(H,58,82)(H,59,70)(H,60,78)(H,61,76)(H,62,77)(H,63,75)(H,64,81)(H,65,79)(H,66,80)(H,72,73)(H2,83,84,85)/t34-,35-,36-,37-,38-,39-,40-,41-,46-/m0/s1 NOPVFRFKBOKXBY-JBSLTYAWSA-N 50124302 3-[6-(4-phosphonooxybenzyl)-27-carbamoyl-12-carbamoylmethyl-24-(4-hydroxybenzyl)-3-isobutyl-15-isopropyl-21-(2-methylsulfanylethyl)-1,4,7,10,13,16,19,22,25,31-decaoxoperhydropyrrolo[1,2-d][1,4,7,10,13,16,19,22,25,28,31]thiadecaazacyclotritriacontin-9-yl]propanoic acid::CHEMBL2371611 Growth factor receptor-bound protein 2 Homo sapiens 76 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124302&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73348605 104016639 CHEMBL2371611 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50225244 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 BZLRZJFFHMIABH-AGEHIQCHSA-N 50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide Growth factor receptor-bound protein 2 Homo sapiens >100000000 ChEMBL 10.1016/s0960-894x(03)00015-5 10.7270/Q2SF2VH2 12617916 Li, P; Peach, ML; Zhang, M; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124303&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383302 104016640 CHEMBL444114 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235926 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](NC(=O)CCCNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C25H36N5O8P/c26-20(31)13-19-23(34)27-12-4-5-21(32)28-18(17-8-6-16(7-9-17)15-39(36,37)38)14-22(33)30-25(24(35)29-19)10-2-1-3-11-25/h6-9,18-19H,1-5,10-15H2,(H2,26,31)(H,27,34)(H,28,32)(H,29,35)(H,30,33)(H2,36,37,38)/t18-,19-/m0/s1 WEJLCKWUWDORQV-OALUTQOASA-N 50129630 CHEMBL422957::[4-(18-Carbamoylmethyl-8,12,17,20-tetraoxo-7,11,16,19-tetraaza-spiro[5.14]icos-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 47900 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129630&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44322503 104021206 CHEMBL422957 ZINC26641338 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235927 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)CCc1ccc(CP(O)(O)=O)cc1)C(N)=O InChI=1S/C21H31N4O7P/c22-17(26)12-16(19(23)28)24-20(29)21(10-2-1-3-11-21)25-18(27)9-8-14-4-6-15(7-5-14)13-33(30,31)32/h4-7,16H,1-3,8-13H2,(H2,22,26)(H2,23,28)(H,24,29)(H,25,27)(H2,30,31,32)/t16-/m0/s1 FXKHQBNGLUTFLT-INIZCTEOSA-N 50129631 (4-{2-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-ethyl}-benzyl)-phosphonic acid::CHEMBL88739 Growth factor receptor-bound protein 2 Homo sapiens 52500 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129631&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10972892 104021207 CHEMBL88739 ZINC13521822 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235928 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](NC(=O)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C23H32N5O8P/c24-18(29)10-17-21(32)25-12-20(31)26-16(15-6-4-14(5-7-15)13-37(34,35)36)11-19(30)28-23(22(33)27-17)8-2-1-3-9-23/h4-7,16-17H,1-3,8-13H2,(H2,24,29)(H,25,32)(H,26,31)(H,27,33)(H,28,30)(H2,34,35,36)/t16-,17-/m0/s1 DRUJNXGREHWPNJ-IRXDYDNUSA-N 50129632 CHEMBL91584::[4-(16-Carbamoylmethyl-8,12,15,18-tetraoxo-7,11,14,17-tetraaza-spiro[5.12]octadec-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >600000 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129632&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44322505 104021208 CHEMBL91584 ZINC26639522 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235929 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 26 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235930 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](NC(=O)CCNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C24H34N5O8P/c25-19(30)12-18-22(33)26-11-8-20(31)27-17(16-6-4-15(5-7-16)14-38(35,36)37)13-21(32)29-24(23(34)28-18)9-2-1-3-10-24/h4-7,17-18H,1-3,8-14H2,(H2,25,30)(H,26,33)(H,27,31)(H,28,34)(H,29,32)(H2,35,36,37)/t17-,18-/m0/s1 BEFXVSBZHPQWES-ROUUACIJSA-N 50129633 CHEMBL91880::[4-(17-Carbamoylmethyl-8,12,16,19-tetraoxo-7,11,15,18-tetraaza-spiro[5.13]nonadec-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens >600000 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129633&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44322504 104021209 CHEMBL91880 ZINC26641344 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235931 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](NC(=O)C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C36H44N5O8P/c37-31(42)19-30-34(45)38-21-24(17-27-9-6-8-25-7-2-3-10-28(25)27)18-32(43)39-29(26-13-11-23(12-14-26)22-50(47,48)49)20-33(44)41-36(35(46)40-30)15-4-1-5-16-36/h2-3,6-14,24,29-30H,1,4-5,15-22H2,(H2,37,42)(H,38,45)(H,39,43)(H,40,46)(H,41,44)(H2,47,48,49)/t24-,29+,30+/m1/s1 VVFFVOVDUTZPET-FRDKBHKLSA-N 50129634 CHEMBL90990::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,12,17,20-tetraoxo-7,11,16,19-tetraaza-spiro[5.14]icos-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 7900 ChEMBL 10.1021/jm030049q 10.7270/Q2C828PT 12801226 Lee, K; Zhang, M; Liu, H; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129634&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10462458 104021210 CHEMBL90990 ZINC26638459 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235424 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C68H86N12O18S/c1-36(2)27-46-58(87)76-49(30-40-17-23-44(82)24-18-40)63(92)80-68(25-9-6-10-26-68)67(98)78-51(32-53(69)83)62(91)79-56(37(3)4)64(93)71-33-54(84)72-47(28-38-13-19-42(20-14-38)41-11-7-5-8-12-41)59(88)75-48(29-39-15-21-43(81)22-16-39)60(89)77-52(57(70)86)34-99-35-55(85)73-50(61(90)74-46)31-45(65(94)95)66(96)97/h5,7-8,11-24,36-37,45-52,56,81-82H,6,9-10,25-35H2,1-4H3,(H2,69,83)(H2,70,86)(H,71,93)(H,72,84)(H,73,85)(H,74,90)(H,75,88)(H,76,87)(H,77,89)(H,78,98)(H,79,91)(H,80,92)(H,94,95)(H,96,97)/t46-,47-,48+,49+,50+,51+,52+,56-/m1/s1 RUPJWLFUBKJCOW-YIVXIEOVSA-N 50129411 CHEMBL266273::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Bip Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 502 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129411&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309173 104020994 CHEMBL266273 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235425 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2c(F)c(F)c(F)c(F)c2F)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C62H77F5N12O18S/c1-27(2)18-35-52(86)75-37(20-30-10-14-32(81)15-11-30)57(91)79-62(16-6-5-7-17-62)61(97)77-40(23-42(68)82)56(90)78-50(28(3)4)58(92)70-24-43(83)71-38(21-33-45(63)47(65)49(67)48(66)46(33)64)54(88)74-36(19-29-8-12-31(80)13-9-29)53(87)76-41(51(69)85)25-98-26-44(84)72-39(55(89)73-35)22-34(59(93)94)60(95)96/h8-15,27-28,34-41,50,80-81H,5-7,16-26H2,1-4H3,(H2,68,82)(H2,69,85)(H,70,92)(H,71,83)(H,72,84)(H,73,89)(H,74,88)(H,75,86)(H,76,87)(H,77,97)(H,78,90)(H,79,91)(H,93,94)(H,95,96)/t35-,36+,37+,38-,39+,40+,41+,50-/m1/s1 BJMLMENHANPHLN-CIRFFWHWSA-N 50129412 CHEMBL413683::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly F5Phe Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 238 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129412&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309172 104020995 CHEMBL413683 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235426 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C57H80N12O20S2/c1-27(2)19-36-50(80)66-37(20-29-9-13-31(70)14-10-29)51(81)63-34(7-6-8-45(75)76)48(78)67-40(23-42(58)72)54(84)69-46(28(3)4)55(85)60-24-43(73)61-35(17-18-90-5)49(79)65-38(21-30-11-15-32(71)16-12-30)52(82)68-41(47(59)77)25-91-26-44(74)62-39(53(83)64-36)22-33(56(86)87)57(88)89/h9-16,27-28,33-41,46,70-71H,6-8,17-26H2,1-5H3,(H2,58,72)(H2,59,77)(H,60,85)(H,61,73)(H,62,74)(H,63,81)(H,64,83)(H,65,79)(H,66,80)(H,67,78)(H,68,82)(H,69,84)(H,75,76)(H,86,87)(H,88,89)/t34-,35-,36-,37+,38+,39+,40+,41+,46-/m1/s1 WZPWAUWMIGGVKG-HXXNBMRUSA-N 50129413 CHEMBL405191::cyclic ((N-AC)Gla Leu Tyr Adi Asn Val Gly Met Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 1510 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129413&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309024 104020996 CHEMBL405191 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235427 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)(C)C)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C60H86N12O18S/c1-30(2)21-37-49(79)68-39(23-33-13-17-35(74)18-14-33)54(84)72-60(19-9-8-10-20-60)58(90)70-41(25-44(61)75)52(82)71-47(31(3)4)55(85)63-27-45(76)65-42(26-59(5,6)7)53(83)67-38(22-32-11-15-34(73)16-12-32)50(80)69-43(48(62)78)28-91-29-46(77)64-40(51(81)66-37)24-36(56(86)87)57(88)89/h11-18,30-31,36-43,47,73-74H,8-10,19-29H2,1-7H3,(H2,61,75)(H2,62,78)(H,63,85)(H,64,77)(H,65,76)(H,66,81)(H,67,83)(H,68,79)(H,69,80)(H,70,90)(H,71,82)(H,72,84)(H,86,87)(H,88,89)/t37-,38+,39+,40+,41+,42-,43+,47-/m1/s1 CUVFTTYTYVIUBF-XEUJSLSQSA-N 50129415 CHEMBL437329::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 244 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129415&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309164 104020998 CHEMBL437329 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235429 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C66H84N12O18S/c1-34(2)24-44-56(85)74-47(27-37-15-20-42(80)21-16-37)61(90)78-66(22-8-5-9-23-66)65(96)76-49(30-51(67)81)60(89)77-54(35(3)4)62(91)69-31-52(82)70-45(28-38-12-17-39-10-6-7-11-40(39)25-38)57(86)73-46(26-36-13-18-41(79)19-14-36)58(87)75-50(55(68)84)32-97-33-53(83)71-48(59(88)72-44)29-43(63(92)93)64(94)95/h6-7,10-21,25,34-35,43-50,54,79-80H,5,8-9,22-24,26-33H2,1-4H3,(H2,67,81)(H2,68,84)(H,69,91)(H,70,82)(H,71,83)(H,72,88)(H,73,86)(H,74,85)(H,75,87)(H,76,96)(H,77,89)(H,78,90)(H,92,93)(H,94,95)/t44-,45-,46+,47+,48+,49+,50+,54-/m1/s1 MZDWUEHZUCAGKK-BCARVFFCSA-N 50129416 CHEMBL411181::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly 2-Nal Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 271 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129416&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309257 104020999 CHEMBL411181 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235433 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@]2(CC3CCC2C3)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C59H82N12O18S2/c1-28(2)18-38-50(79)67-40(21-31-9-14-35(73)15-10-31)54(83)71-59(24-32-6-11-33(59)19-32)58(89)69-42(23-44(60)74)53(82)70-47(29(3)4)55(84)62-25-45(75)63-37(16-17-90-5)49(78)66-39(20-30-7-12-34(72)13-8-30)51(80)68-43(48(61)77)26-91-27-46(76)64-41(52(81)65-38)22-36(56(85)86)57(87)88/h7-10,12-15,28-29,32-33,36-43,47,72-73H,6,11,16-27H2,1-5H3,(H2,60,74)(H2,61,77)(H,62,84)(H,63,75)(H,64,76)(H,65,81)(H,66,78)(H,67,79)(H,68,80)(H,69,89)(H,70,82)(H,71,83)(H,85,86)(H,87,88)/t32?,33?,37-,38-,39-,40-,41-,42-,43-,47-,59-/m0/s1 OYOFJTPMGAGDHV-XRAFEHCDSA-N 50129419 CHEMBL2369467::cyclic ((N-AC)Gla Leu Tyr BCH Asn Val Gly Met Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 730 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129419&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73351481 104021002 CHEMBL2369467 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235436 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C56H78N12O20S2/c1-26(2)18-35-49(79)65-36(19-28-6-10-30(69)11-7-28)50(80)62-33(14-15-44(74)75)47(77)66-39(22-41(57)71)53(83)68-45(27(3)4)54(84)59-23-42(72)60-34(16-17-89-5)48(78)64-37(20-29-8-12-31(70)13-9-29)51(81)67-40(46(58)76)24-90-25-43(73)61-38(52(82)63-35)21-32(55(85)86)56(87)88/h6-13,26-27,32-40,45,69-70H,14-25H2,1-5H3,(H2,57,71)(H2,58,76)(H,59,84)(H,60,72)(H,61,73)(H,62,80)(H,63,82)(H,64,78)(H,65,79)(H,66,77)(H,67,81)(H,68,83)(H,74,75)(H,85,86)(H,87,88)/t33-,34-,35-,36+,37+,38+,39+,40+,45-/m1/s1 WUIYUDVETVSNJA-DXLQUIRLSA-N 50129421 CHEMBL217433::cyclic ((N-AC)Gla Leu Tyr Pro Asn Val Gly Met Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 991 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129421&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309150 104021004 CHEMBL217433 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235437 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C1CCCCC1)C(N)=O InChI=1S/C61H86N12O18S/c1-31(2)23-39-51(80)67-41(25-34-15-19-37(75)20-16-34)55(84)73-61(21-9-6-10-22-61)60(91)70-43(27-45(62)76)54(83)72-48(32(3)4)56(85)64-28-46(77)71-49(35-11-7-5-8-12-35)57(86)68-40(24-33-13-17-36(74)18-14-33)52(81)69-44(50(63)79)29-92-30-47(78)65-42(53(82)66-39)26-38(58(87)88)59(89)90/h13-20,31-32,35,38-44,48-49,74-75H,5-12,21-30H2,1-4H3,(H2,62,76)(H2,63,79)(H,64,85)(H,65,78)(H,66,82)(H,67,80)(H,68,86)(H,69,81)(H,70,91)(H,71,77)(H,72,83)(H,73,84)(H,87,88)(H,89,90)/t39-,40+,41+,42+,43+,44+,48-,49-/m1/s1 XQCDENWBAQOTEF-YLFBIEGKSA-N 50129424 CHEMBL410772::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 815.0 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129424&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309174 104021007 CHEMBL410772 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235439 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O16S2/c1-28(2)21-36-50(78)64-39(23-31-10-14-33(69)15-11-31)55(83)67-19-6-7-41(67)53(81)63-38(24-42(56)70)52(80)66-46(29(3)4)54(82)58-25-43(71)59-35(18-20-84-5)49(77)62-37(22-30-8-12-32(68)13-9-30)51(79)65-40(47(57)75)26-85-27-44(72)60-34(48(76)61-36)16-17-45(73)74/h8-15,28-29,34-41,46,68-69H,6-7,16-27H2,1-5H3,(H2,56,70)(H2,57,75)(H,58,82)(H,59,71)(H,60,72)(H,61,76)(H,62,77)(H,63,81)(H,64,78)(H,65,79)(H,66,80)(H,73,74)/t34-,35-,36-,37-,38-,39-,40-,41-,46-/m0/s1 DAXMLPHUFZLWND-JBSLTYAWSA-N 50129422 CHEMBL2369460::cyclic ((N-AC)Glu Leu Tyr Glu Asn Val Gly Met Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 7830 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129422&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73356027 104021005 CHEMBL2369460 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235440 CSCC[C@H]1NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C58H82N12O18S2/c1-29(2)21-37-49(78)66-39(23-32-11-15-34(72)16-12-32)53(82)70-58(18-7-6-8-19-58)57(88)68-41(25-43(59)73)52(81)69-46(30(3)4)54(83)61-26-44(74)62-36(17-20-89-5)48(77)65-38(22-31-9-13-33(71)14-10-31)50(79)67-42(47(60)76)27-90-28-45(75)63-40(51(80)64-37)24-35(55(84)85)56(86)87/h9-16,29-30,35-42,46,71-72H,6-8,17-28H2,1-5H3,(H2,59,73)(H2,60,76)(H,61,83)(H,62,74)(H,63,75)(H,64,80)(H,65,77)(H,66,78)(H,67,79)(H,68,88)(H,69,81)(H,70,82)(H,84,85)(H,86,87)/t36-,37-,38+,39+,40+,41+,42+,46-/m1/s1 CZTLVHIHJOQOPI-HCDABZKUSA-N 50129423 CHEMBL407241::cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Met Tyr Cys NH2) Growth factor receptor-bound protein 2 Homo sapiens 525 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129423&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309256 104021006 CHEMBL407241 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235441 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C1CCCCC1)C(N)=O InChI=1S/C61H86N12O19S/c1-31(2)23-39-51(80)67-41(25-34-15-19-37(75)20-16-34)55(84)73-61(21-9-6-10-22-61)60(91)70-43(27-45(62)76)54(83)72-48(32(3)4)56(85)64-28-46(77)71-49(35-11-7-5-8-12-35)57(86)68-40(24-33-13-17-36(74)18-14-33)52(81)69-44(50(63)79)29-93(92)30-47(78)65-42(53(82)66-39)26-38(58(87)88)59(89)90/h13-20,31-32,35,38-44,48-49,74-75H,5-12,21-30H2,1-4H3,(H2,62,76)(H2,63,79)(H,64,85)(H,65,78)(H,66,82)(H,67,80)(H,68,86)(H,69,81)(H,70,91)(H,71,77)(H,72,83)(H,73,84)(H,87,88)(H,89,90)/t39-,40+,41+,42+,43+,44+,48-,49-,93?/m1/s1 PQOPKORIBIGSBW-QVNPOUQNSA-N 50129420 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys(O) NH2)::CHEMBL406289 Growth factor receptor-bound protein 2 Homo sapiens 149 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129420&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309042 104021003 CHEMBL406289 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50256706 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 0.093 ChEMBL 10.1021/jm030440b 10.7270/Q2XD114Q 14761181 Shi, ZD; Lee, K; Wei, CQ; Roberts, LR; Worthy, KM; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50256707 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1021/jm030440b 10.7270/Q2XD114Q 14761181 Shi, ZD; Lee, K; Wei, CQ; Roberts, LR; Worthy, KM; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50256708 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1 YWOITRAWXNSFNB-FETINEJHSA-N 50139763 CHEMBL306657::[(E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2 ChEMBL 10.1021/jm030440b 10.7270/Q2XD114Q 14761181 Shi, ZD; Lee, K; Wei, CQ; Roberts, LR; Worthy, KM; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139763&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10259481 104029592 CHEMBL306657 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50256709 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC([O-])=O)[C@H](\C=C\C3)c3ccc(CP([O-])([O-])=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/p-3/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-K 50139764 5-Methylindolyl derivative::CHEMBL423988 Growth factor receptor-bound protein 2 Homo sapiens 0.075 ChEMBL 10.1021/jm030440b 10.7270/Q2XD114Q 14761181 Shi, ZD; Lee, K; Wei, CQ; Roberts, LR; Worthy, KM; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139764&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 91932751 104029593 CHEMBL423988 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270694 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H72N10O14S/c1-26(2)21-31-42(66)54-32(22-28-14-16-29(58)17-15-28)44(68)57-47(18-7-5-8-19-47)46(70)55-33(23-35(48)59)43(67)56-39(27(3)4)45(69)50-20-9-6-12-36(60)52-34(40(49)64)24-72(71)25-37(61)51-30(41(65)53-31)11-10-13-38(62)63/h14-17,26-27,30-34,39,58H,5-13,18-25H2,1-4H3,(H2,48,59)(H2,49,64)(H,50,69)(H,51,61)(H,52,60)(H,53,65)(H,54,66)(H,55,70)(H,56,67)(H,57,68)(H,62,63)/t30-,31-,32-,33-,34-,39-,72?/m0/s1 XRLGKMHNCUYAQL-FOMUXWDSSA-N 50147392 (R)-21-Carbamoyl-33-carbamoylmethyl-15-((S)-3-carboxy-propyl)-9-((S)-4-hydroxy-benzyl)-12-((S)-isobutyl)-30-((S)-isopropyl)-8,11,14,17,23,29,32-heptaoxo-35-(S)-oxo-19lambda*4*-thia-7,10,13,16,22,28,31,34-octaaza-spiro[5.29]pentatriacontan-19-ol anion::CHEMBL408922 Growth factor receptor-bound protein 2 Homo sapiens 9800.0 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147392&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338553 104035884 CHEMBL408922 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270695 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H71N11O16S/c1-23(2)16-28-39(64)55-29(18-25-11-12-33(59)27(48)17-25)42(67)58-47(13-7-5-8-14-47)46(73)56-31(20-34(49)60)41(66)57-37(24(3)4)43(68)51-15-9-6-10-35(61)53-32(38(50)63)21-75(74)22-36(62)52-30(40(65)54-28)19-26(44(69)70)45(71)72/h11-12,17,23-24,26,28-32,37,59H,5-10,13-16,18-22,48H2,1-4H3,(H2,49,60)(H2,50,63)(H,51,68)(H,52,62)(H,53,61)(H,54,65)(H,55,64)(H,56,73)(H,57,66)(H,58,67)(H,69,70)(H,71,72)/t28-,29-,30-,31-,32+,37-,75?/m0/s1 OVBRGKZTKQSNRM-JTRKXDDTSA-N 50147391 CHEMBL266791::Hexapeptide derivative Growth factor receptor-bound protein 2 Homo sapiens 1080 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147391&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338806 104035883 CHEMBL266791 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270696 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H71N11O15S/c1-23(2)16-28-39(64)55-29(18-25-11-12-33(59)27(48)17-25)42(67)58-47(13-7-5-8-14-47)46(73)56-31(20-34(49)60)41(66)57-37(24(3)4)43(68)51-15-9-6-10-35(61)53-32(38(50)63)21-74-22-36(62)52-30(40(65)54-28)19-26(44(69)70)45(71)72/h11-12,17,23-24,26,28-32,37,59H,5-10,13-16,18-22,48H2,1-4H3,(H2,49,60)(H2,50,63)(H,51,68)(H,52,62)(H,53,61)(H,54,65)(H,55,64)(H,56,73)(H,57,66)(H,58,67)(H,69,70)(H,71,72)/t28-,29-,30-,31-,32-,37-/m0/s1 MVONVWIWPFDXKI-XJJOYFJPSA-N 50147393 2-[(R)-9-((S)-3-Amino-4-hydroxy-benzyl)-21-carbamoyl-33-carbamoylmethyl-12-((S)-isobutyl)-30-((S)-isopropyl)-8,11,14,17,23,29,32-heptaoxo-35-(S)-oxo-19-thia-7,10,13,16,22,28,31,34-octaaza-spiro[5.29]pentatriacont-15-ylmethyl]-malonic acid::CHEMBL265254 Growth factor receptor-bound protein 2 Homo sapiens 160 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147393&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338797 104035885 CHEMBL265254 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270697 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H72N10O13S/c1-26(2)21-31-42(66)54-32(22-28-14-16-29(58)17-15-28)44(68)57-47(18-7-5-8-19-47)46(70)55-33(23-35(48)59)43(67)56-39(27(3)4)45(69)50-20-9-6-12-36(60)52-34(40(49)64)24-71-25-37(61)51-30(41(65)53-31)11-10-13-38(62)63/h14-17,26-27,30-34,39,58H,5-13,18-25H2,1-4H3,(H2,48,59)(H2,49,64)(H,50,69)(H,51,61)(H,52,60)(H,53,65)(H,54,66)(H,55,70)(H,56,67)(H,57,68)(H,62,63)/t30-,31-,32-,33-,34-,39-/m0/s1 KHIXYXLODHULIH-LKOQSZQXSA-N 50147394 4-[(R)-21-Carbamoyl-33-carbamoylmethyl-9-((S)-4-hydroxy-benzyl)-12-((S)-isobutyl)-30-((S)-isopropyl)-8,11,14,17,23,29,32-heptaoxo-35-(S)-oxo-19-thia-7,10,13,16,22,28,31,34-octaaza-spiro[5.29]pentatriacont-15-yl]-butyric acid::CHEMBL266080 Growth factor receptor-bound protein 2 Homo sapiens 11400 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147394&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338552 104035886 CHEMBL266080 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270698 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C46H68N10O17S/c1-22(2)16-28-40(65)54-29(17-24-11-13-25(57)14-12-24)41(66)52-27(8-7-10-36(61)62)39(64)55-31(19-33(47)58)43(68)56-37(23(3)4)44(69)49-15-6-5-9-34(59)51-32(38(48)63)20-74-21-35(60)50-30(42(67)53-28)18-26(45(70)71)46(72)73/h11-14,22-23,26-32,37,57H,5-10,15-21H2,1-4H3,(H2,47,58)(H2,48,63)(H,49,69)(H,50,60)(H,51,59)(H,52,66)(H,53,67)(H,54,65)(H,55,64)(H,56,68)(H,61,62)(H,70,71)(H,72,73)/t27-,28-,29-,30-,31-,32-,37-/m0/s1 PXAHNSFMMQPHRE-KXEZSSGCSA-N 50147396 2-[(R)-29-Carbamoyl-17-carbamoylmethyl-14-((S)-3-carboxy-propyl)-11-((S)-4-hydroxy-benzyl)-8-((S)-isobutyl)-20-((S)-isopropyl)-3,15-di(S)-oxo-6,9,12,18,21,27-hexaoxo-1-thia-4,7,10,13,16,19,22,28-octaaza-cyclotriacont-5-ylmethyl]-malonic acid::CHEMBL427607 Growth factor receptor-bound protein 2 Homo sapiens 23300 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147396&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338463 104035888 CHEMBL427607 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270699 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H72N10O14S/c1-26(2)21-31-42(66)54-32(22-28-14-16-29(58)17-15-28)44(68)57-47(18-7-5-8-19-47)46(70)55-33(23-35(48)59)43(67)56-39(27(3)4)45(69)50-20-9-6-12-36(60)52-34(40(49)64)24-72(71)25-37(61)51-30(41(65)53-31)11-10-13-38(62)63/h14-17,26-27,30-34,39,58H,5-13,18-25H2,1-4H3,(H2,48,59)(H2,49,64)(H,50,69)(H,51,61)(H,52,60)(H,53,65)(H,54,66)(H,55,70)(H,56,67)(H,57,68)(H,62,63)/t30-,31-,32-,33-,34+,39-,72?/m0/s1 XRLGKMHNCUYAQL-ZASFAMSOSA-N 50147395 (S)-21-Carbamoyl-33-carbamoylmethyl-15-((S)-3-carboxy-propyl)-9-((S)-4-hydroxy-benzyl)-12-((S)-isobutyl)-30-((S)-isopropyl)-8,11,14,17,23,29,32-heptaoxo-35-(S)-oxo-19lambda*4*-thia-7,10,13,16,22,28,31,34-octaaza-spiro[5.29]pentatriacontan-19-ol anion::CHEMBL414039 Growth factor receptor-bound protein 2 Homo sapiens 84500.0 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147395&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338554 104035887 CHEMBL414039 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50270700 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(C)C)C(N)=O InChI=1S/C47H71N11O16S/c1-23(2)16-28-39(64)55-29(18-25-11-12-33(59)27(48)17-25)42(67)58-47(13-7-5-8-14-47)46(73)56-31(20-34(49)60)41(66)57-37(24(3)4)43(68)51-15-9-6-10-35(61)53-32(38(50)63)21-75(74)22-36(62)52-30(40(65)54-28)19-26(44(69)70)45(71)72/h11-12,17,23-24,26,28-32,37,59H,5-10,13-16,18-22,48H2,1-4H3,(H2,49,60)(H2,50,63)(H,51,68)(H,52,62)(H,53,61)(H,54,65)(H,55,64)(H,56,73)(H,57,66)(H,58,67)(H,69,70)(H,71,72)/t28-,29-,30-,31-,32-,37-,75?/m0/s1 OVBRGKZTKQSNRM-SRKGPBQKSA-N 50147397 CHEMBL444897::Hexapeptide derivative Growth factor receptor-bound protein 2 Homo sapiens 50 ChEMBL 10.1016/j.bmcl.2004.03.103 10.7270/Q28K78J3 15149676 Song, YL; Roller, PP; Long, YQ Institute of Materia Medica http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147397&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44338798 104035889 CHEMBL444897 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264693 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 ZOJQPGFTWKKVQO-NSOVKSMOSA-N 50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150 Growth factor receptor-bound protein 2 Homo sapiens 22.1 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9896853 103985277 CHEMBL303150 ZINC95610086 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264694 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1 YWOITRAWXNSFNB-FETINEJHSA-N 50139763 CHEMBL306657::[(E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 1.4 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139763&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10259481 104029592 CHEMBL306657 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264695 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C([O-])=O)C([O-])=O InChI=1S/C41H46N4O10/c42-33(46)22-32-37(50)43-23-24(20-28-11-7-10-25-9-2-3-12-29(25)28)8-6-13-30(26-14-16-27(17-15-26)35(38(51)52)39(53)54)31(21-34(47)48)36(49)45-41(40(55)44-32)18-4-1-5-19-41/h2-3,6-7,9-17,24,30-32,35H,1,4-5,8,18-23H2,(H2,42,46)(H,43,50)(H,44,55)(H,45,49)(H,47,48)(H,51,52)(H,53,54)/p-2/b13-6+/t24-,30+,31-,32-/m0/s1 FYIJOFSDJMOTGX-SPRVXXEPSA-L 50143944 2-[4-((E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-9-carboxymethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-phenyl]-malonate;disodium::CHEMBL70024 Growth factor receptor-bound protein 2 Homo sapiens 4.3 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143944&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 91932894 104033079 CHEMBL70024 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264696 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C([O-])=O)C([O-])=O InChI=1S/C41H46N4O10/c42-33(46)22-32-37(50)43-23-24(20-28-11-7-10-25-9-2-3-12-29(25)28)8-6-13-30(26-14-16-27(17-15-26)35(38(51)52)39(53)54)31(21-34(47)48)36(49)45-41(40(55)44-32)18-4-1-5-19-41/h2-3,6-7,9-17,24,30-32,35H,1,4-5,8,18-23H2,(H2,42,46)(H,43,50)(H,44,55)(H,45,49)(H,47,48)(H,51,52)(H,53,54)/p-2/b13-6+/t24-,30+,31-,32-/m0/s1 FYIJOFSDJMOTGX-SPRVXXEPSA-L 50143944 2-[4-((E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-9-carboxymethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-phenyl]-malonate;disodium::CHEMBL70024 Growth factor receptor-bound protein 2 Homo sapiens 12.1 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143944&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 91932894 104033079 CHEMBL70024 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264697 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1 LBUZYNYSEBMSDQ-VMPREFPWSA-N 50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 10 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072865&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 398462 103966456 CHEMBL55627 ZINC29552457 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50264698 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1 YWOITRAWXNSFNB-FETINEJHSA-N 50139763 CHEMBL306657::[(E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 1.40 ChEMBL 10.1021/jm030510e 10.7270/Q2668CNN 15056012 Shi, ZD; Wei, CQ; Lee, K; Liu, H; Zhang, M; Araki, T; Roberts, LR; Worthy, KM; Fisher, RJ; Neel, BG; Kelley, JA; Yang, D; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139763&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10259481 104029592 CHEMBL306657 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50297240 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H45N4O9P/c37-31(41)22-30(34(45)38-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27)39-35(46)36(17-4-1-5-18-36)40-33(44)28(21-32(42)43)20-24-13-15-25(16-14-24)23-50(47,48)49/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1 AYRBFDFQLSQIBI-DGPALRBDSA-N 50118687 (R)-N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-(4-phosphonomethyl-benzyl)-succinamic acid::CHEMBL93367::N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-3-((R)-3-phosphonomethyl-benzyl)-succinamic acid Growth factor receptor-bound protein 2 Homo sapiens 23.8 4180000 0.0991 ChEMBL 10.1016/j.bmcl.2005.01.017 10.7270/Q22R3R59 15713392 Shi, ZD; Karki, RG; Oishi, S; Worthy, KM; Bindu, LK; Dharmawardana, PG; Nicklaus, MC; Bottaro, DP; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118687&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987336 104011951 CHEMBL93367 ZINC26663353 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50297241 NC(=O)CC(NC(=O)C1(CCCCC1)NC(=O)C(CC(O)=O)Cc1ccc(C[P+](O)(O)[O-])cc1)C(=O)NCCNc1ccc([N+]([O-])=O)c2n[o+][n-]c12 InChI=1S/C31H39N8O12P/c32-24(40)16-22(29(44)34-13-12-33-21-8-9-23(39(46)47)27-26(21)37-51-38-27)35-30(45)31(10-2-1-3-11-31)36-28(43)20(15-25(41)42)14-18-4-6-19(7-5-18)17-52(48,49)50/h4-9,20,22,33H,1-3,10-17H2,(H2,32,40)(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H2,48,49,50) LKYLLHOSMFJONU-UHFFFAOYSA-N 50161466 (R)-N-(1-{(S)-2-Carbamoyl-1-[2-(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino)-ethylcarbamoyl]-ethylcarbamoyl}-cyclohexyl)-3-(4-phosphonomethyl-benzyl)-succinamic acid::CHEMBL362853 Growth factor receptor-bound protein 2 Homo sapiens 167 ChEMBL 10.1016/j.bmcl.2005.01.017 10.7270/Q22R3R59 15713392 Shi, ZD; Karki, RG; Oishi, S; Worthy, KM; Bindu, LK; Dharmawardana, PG; Nicklaus, MC; Bottaro, DP; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161466&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 85423253 104047772 CHEMBL362853 ZINC95612455 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50297242 NC(=O)CC(NC(=O)C1(CCCCC1)NC(=O)C(CC(O)=O)Cc1ccc(C[P+](O)(O)[O-])cc1)C(=O)NCCNc1ccc([N+]([O-])=O)c2n[o+][n-]c12 InChI=1S/C31H39N8O12P/c32-24(40)16-22(29(44)34-13-12-33-21-8-9-23(39(46)47)27-26(21)37-51-38-27)35-30(45)31(10-2-1-3-11-31)36-28(43)20(15-25(41)42)14-18-4-6-19(7-5-18)17-52(48,49)50/h4-9,20,22,33H,1-3,10-17H2,(H2,32,40)(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H2,48,49,50) LKYLLHOSMFJONU-UHFFFAOYSA-N 50161466 (R)-N-(1-{(S)-2-Carbamoyl-1-[2-(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino)-ethylcarbamoyl]-ethylcarbamoyl}-cyclohexyl)-3-(4-phosphonomethyl-benzyl)-succinamic acid::CHEMBL362853 Growth factor receptor-bound protein 2 Homo sapiens 119 1180000 0.14 ChEMBL 10.1016/j.bmcl.2005.01.017 10.7270/Q22R3R59 15713392 Shi, ZD; Karki, RG; Oishi, S; Worthy, KM; Bindu, LK; Dharmawardana, PG; Nicklaus, MC; Bottaro, DP; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161466&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 85423253 104047772 CHEMBL362853 ZINC95612455 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296208 NC(=O)C[C@H](NC(=O)CCCCCNC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H45N4O9P/c36-31(40)22-30(35(45)38-19-7-11-27-10-6-9-26-8-3-4-12-29(26)27)39-32(41)13-2-1-5-18-37-34(44)28(21-33(42)43)20-24-14-16-25(17-15-24)23-49(46,47)48/h3-4,6,8-10,12,14-17,28,30H,1-2,5,7,11,13,18-23H2,(H2,36,40)(H,37,44)(H,38,45)(H,39,41)(H,42,43)(H2,46,47,48)/t28-,30+/m1/s1 RHENIHXWHJZKOZ-DGPALRBDSA-N 50161188 (S)-4-{4-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-butylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL175689 Growth factor receptor-bound protein 2 Homo sapiens 97.8 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161188&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44388011 104047566 CHEMBL175689 ZINC28113854 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296209 C[C@@]1(Cc2ccc(cc2)P(O)(O)=O)NC(=O)CC(\C=C\C[C@@H](Cc2cccc3ccccc23)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C40H46N4O10P2/c1-40(23-26-14-18-33(19-15-26)56(52,53)54)39(48)43-35(22-36(41)45)38(47)42-24-28(20-32-10-5-8-30-7-2-3-11-34(30)32)6-4-9-31(21-37(46)44-40)29-16-12-27(13-17-29)25-55(49,50)51/h2-5,7-19,28,31,35H,6,20-25H2,1H3,(H2,41,45)(H,42,47)(H,43,48)(H,44,46)(H2,49,50,51)(H2,52,53,54)/b9-4+/t28-,31?,35-,40-/m0/s1 GPPWBJRNTGJGNA-XGIJUFSJSA-N 50161189 (S)-4-{5-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL175456 Growth factor receptor-bound protein 2 Homo sapiens 2.28 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161189&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387910 104047567 CHEMBL175456 ZINC95606393 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296210 NC(=O)C[C@H](NC(=O)CCNC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C32H39N4O9P/c33-28(37)19-27(32(42)34-15-4-8-24-7-3-6-23-5-1-2-9-26(23)24)36-29(38)14-16-35-31(41)25(18-30(39)40)17-21-10-12-22(13-11-21)20-46(43,44)45/h1-3,5-7,9-13,25,27H,4,8,14-20H2,(H2,33,37)(H,34,42)(H,35,41)(H,36,38)(H,39,40)(H2,43,44,45)/t25-,27+/m1/s1 QWSFJNCENPNFHZ-VPUSJEBWSA-N 50161190 CHEMBL424969::Phosphoric acid mono-[(S)-4-(2-acetylamino-2-{2-[(S)-2aarbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl -ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 23.8 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161190&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387971 104047568 CHEMBL424969 ZINC28116679 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296211 C[C@@]1(Cc2ccc(cc2)P(O)(O)=O)NC(=O)CC(\C=C\C[C@@H](Cc2cccc3ccccc23)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C40H46N4O10P2/c1-40(23-26-14-18-33(19-15-26)56(52,53)54)39(48)43-35(22-36(41)45)38(47)42-24-28(20-32-10-5-8-30-7-2-3-11-34(30)32)6-4-9-31(21-37(46)44-40)29-16-12-27(13-17-29)25-55(49,50)51/h2-5,7-19,28,31,35H,6,20-25H2,1H3,(H2,41,45)(H,42,47)(H,43,48)(H,44,46)(H2,49,50,51)(H2,52,53,54)/b9-4+/t28-,31?,35-,40-/m0/s1 GPPWBJRNTGJGNA-XGIJUFSJSA-N 50161189 (S)-4-{5-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL175456 Growth factor receptor-bound protein 2 Homo sapiens 0.097 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161189&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387910 104047567 CHEMBL175456 ZINC95606393 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296212 NC(=O)C[C@H](NC(=O)CCCCNC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C34H43N4O9P/c35-30(39)21-29(34(44)37-18-6-10-26-9-5-8-25-7-1-2-11-28(25)26)38-31(40)12-3-4-17-36-33(43)27(20-32(41)42)19-23-13-15-24(16-14-23)22-48(45,46)47/h1-2,5,7-9,11,13-16,27,29H,3-4,6,10,12,17-22H2,(H2,35,39)(H,36,43)(H,37,44)(H,38,40)(H,41,42)(H2,45,46,47)/t27-,29+/m1/s1 QXDGPUCXBSZFOR-PXJZQJOASA-N 50161191 (S)-4-{2-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL414820 Growth factor receptor-bound protein 2 Homo sapiens 14.8 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161191&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44388010 104047569 CHEMBL414820 ZINC28115719 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296213 C[C@@]1(Cc2ccc(cc2)P(O)(O)=O)NC(=O)CC(\C=C\C[C@@H](Cc2cccc3ccccc23)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C40H46N4O10P2/c1-40(23-26-14-18-33(19-15-26)56(52,53)54)39(48)43-35(22-36(41)45)38(47)42-24-28(20-32-10-5-8-30-7-2-3-11-34(30)32)6-4-9-31(21-37(46)44-40)29-16-12-27(13-17-29)25-55(49,50)51/h2-5,7-19,28,31,35H,6,20-25H2,1H3,(H2,41,45)(H,42,47)(H,43,48)(H,44,46)(H2,49,50,51)(H2,52,53,54)/b9-4+/t28-,31?,35-,40-/m0/s1 GPPWBJRNTGJGNA-XGIJUFSJSA-N 50161189 (S)-4-{5-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL175456 Growth factor receptor-bound protein 2 Homo sapiens 2.28 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161189&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387910 104047567 CHEMBL175456 ZINC95606393 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50296214 C[C@@]1(Cc2ccc(cc2)P(O)(O)=O)NC(=O)CC(\C=C\C[C@@H](Cc2cccc3ccccc23)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C40H46N4O10P2/c1-40(23-26-14-18-33(19-15-26)56(52,53)54)39(48)43-35(22-36(41)45)38(47)42-24-28(20-32-10-5-8-30-7-2-3-11-34(30)32)6-4-9-31(21-37(46)44-40)29-16-12-27(13-17-29)25-55(49,50)51/h2-5,7-19,28,31,35H,6,20-25H2,1H3,(H2,41,45)(H,42,47)(H,43,48)(H,44,46)(H2,49,50,51)(H2,52,53,54)/b9-4+/t28-,31?,35-,40-/m0/s1 GPPWBJRNTGJGNA-XGIJUFSJSA-N 50161189 (S)-4-{5-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-5-[4-(1-phosphono-ethyl)-phenyl]-pentanoic acid::CHEMBL175456 Growth factor receptor-bound protein 2 Homo sapiens 4.30 ChEMBL 10.1021/jm0492709 10.7270/Q2C828TM 15689160 Oishi, S; Karki, RG; Kang, SU; Wang, X; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161189&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44387910 104047567 CHEMBL175456 ZINC95606393 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310333 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(cc3)C(C(O)=O)C(O)=O)ccc2c1 InChI=1S/C40H47N5O10/c1-23-8-13-31-27(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-26(12-10-25)34(37(51)52)38(53)54)29(19-33(47)48)35(49)44-40(15-3-2-4-16-40)39(55)43-30(20-32(41)46)36(50)42-21-24/h5,7-14,17-18,24,28-30,34H,2-4,6,15-16,19-22H2,1H3,(H2,41,46)(H,42,50)(H,43,55)(H,44,49)(H,47,48)(H,51,52)(H,53,54)/b7-5+/t24-,28-,29+,30+/m1/s1 ZUXPTLXJHBSAQT-YUAXJFSXSA-N 50168312 2-{4-[(16R,20S)-18-((S)-Carbamoylmethyl)-9-carboxymethyl-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl]-phenyl}-malonic acid::CHEMBL191728 Growth factor receptor-bound protein 2 Homo sapiens 3.62 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168312&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11377706 104053291 CHEMBL191728 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310334 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(O)cc3)ccc2c1 InChI=1S/C37H45N5O7/c1-23-8-13-31-26(18-23)14-17-42(31)22-24-6-5-7-28(25-9-11-27(43)12-10-25)29(19-33(45)46)34(47)41-37(15-3-2-4-16-37)36(49)40-30(20-32(38)44)35(48)39-21-24/h5,7-14,17-18,24,28-30,43H,2-4,6,15-16,19-22H2,1H3,(H2,38,44)(H,39,48)(H,40,49)(H,41,47)(H,45,46)/b7-5+/t24-,28-,29+,30+/m1/s1 KDEFIBQAYWZDCJ-YUAXJFSXSA-N 50168313 CHEMBL191718::[(7S,14R,18S)-18-Carbamoylmethyl-10-(4-hydroxy-phenyl)-14-(5-methyl-indol-1-ylmethyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens >1000 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168313&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11456613 104053292 CHEMBL191718 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310335 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CC(O)=O)cc3)ccc2c1 InChI=1S/C39H47N5O8/c1-24-8-13-32-28(18-24)14-17-44(32)23-26-6-5-7-29(27-11-9-25(10-12-27)19-34(46)47)30(20-35(48)49)36(50)43-39(15-3-2-4-16-39)38(52)42-31(21-33(40)45)37(51)41-22-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,40,45)(H,41,51)(H,42,52)(H,43,50)(H,46,47)(H,48,49)/b7-5+/t26-,29-,30+,31+/m1/s1 WDSHANHIKDRCCI-AZSCFGFUSA-N 50168314 CHEMBL193015::[(7S,14R,18S)-18-Carbamoylmethyl-10-(4-carboxymethyl-phenyl)-14-(5-methyl-indol-1-ylmethyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 22.5 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168314&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11434036 104053293 CHEMBL193015 C03768 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310336 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 15 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310337 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 1.47 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310338 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(NC(=O)C(O)=O)cc3)ccc2c1 InChI=1S/C39H46N6O9/c1-23-8-13-31-26(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-27(12-10-25)42-36(51)37(52)53)29(19-33(47)48)34(49)44-39(15-3-2-4-16-39)38(54)43-30(20-32(40)46)35(50)41-21-24/h5,7-14,17-18,24,28-30H,2-4,6,15-16,19-22H2,1H3,(H2,40,46)(H,41,50)(H,42,51)(H,43,54)(H,44,49)(H,47,48)(H,52,53)/b7-5+/t24-,28-,29+,30+/m1/s1 DGKDBAFVRWNOPJ-YUAXJFSXSA-N 50168316 CHEMBL263328::N-{4-[(7S,14R,18S)-18-Carbamoylmethyl-9-carboxymethyl-14-(5-methyl-indol-1-ylmethyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl]-phenyl}-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 8.8 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168316&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11251209 104053295 CHEMBL263328 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310339 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(cc3)[N+]([O-])=O)ccc2c1 InChI=1S/C37H44N6O8/c1-23-8-13-31-26(18-23)14-17-42(31)22-24-6-5-7-28(25-9-11-27(12-10-25)43(50)51)29(19-33(45)46)34(47)41-37(15-3-2-4-16-37)36(49)40-30(20-32(38)44)35(48)39-21-24/h5,7-14,17-18,24,28-30H,2-4,6,15-16,19-22H2,1H3,(H2,38,44)(H,39,48)(H,40,49)(H,41,47)(H,45,46)/b7-5+/t24-,28-,29+,30+/m1/s1 FWCDFTKTRAVEGX-YUAXJFSXSA-N 50168315 CHEMBL363597::[(7S,14R,18S)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-10-(4-nitro-phenyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens >1000 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168315&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11193334 104053294 CHEMBL363597 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310340 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(=O)Cc4ccccc4)cc3)ccc2c1 InChI=1S/C45H54N5O8P/c1-30-13-18-39-35(23-30)19-22-50(39)27-33-11-8-12-36(34-16-14-32(15-17-34)29-59(57,58)28-31-9-4-2-5-10-31)37(24-41(52)53)42(54)49-45(20-6-3-7-21-45)44(56)48-38(25-40(46)51)43(55)47-26-33/h2,4-5,8-10,12-19,22-23,33,36-38H,3,6-7,11,20-21,24-29H2,1H3,(H2,46,51)(H,47,55)(H,48,56)(H,49,54)(H,52,53)(H,57,58)/b12-8+/t33-,36-,37+,38+/m1/s1 WWHGZGAMKKXJAA-SSXRZIRRSA-N 50168317 CHEMBL193281::[(15R,20S)-10-[4-(Benzyl-hydroxy-phosphinoylmethyl)-phenyl]-18-carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-20-oxo-8,17-di(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 35.3 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168317&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11422983 104053296 CHEMBL193281 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310341 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(NC(=O)C(O)=O)cc3)ccc2c1 InChI=1S/C39H46N6O9/c1-23-8-13-31-26(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-27(12-10-25)42-36(51)37(52)53)29(19-33(47)48)34(49)44-39(15-3-2-4-16-39)38(54)43-30(20-32(40)46)35(50)41-21-24/h5,7-14,17-18,24,28-30H,2-4,6,15-16,19-22H2,1H3,(H2,40,46)(H,41,50)(H,42,51)(H,43,54)(H,44,49)(H,47,48)(H,52,53)/b7-5+/t24-,28-,29+,30+/m1/s1 DGKDBAFVRWNOPJ-YUAXJFSXSA-N 50168316 CHEMBL263328::N-{4-[(7S,14R,18S)-18-Carbamoylmethyl-9-carboxymethyl-14-(5-methyl-indol-1-ylmethyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl]-phenyl}-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 67 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168316&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11251209 104053295 CHEMBL263328 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310342 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(C)(O)=O)cc3)ccc2c1 InChI=1S/C39H50N5O8P/c1-25-9-14-33-29(19-25)15-18-44(33)23-27-7-6-8-30(28-12-10-26(11-13-28)24-53(2,51)52)31(20-35(46)47)36(48)43-39(16-4-3-5-17-39)38(50)42-32(21-34(40)45)37(49)41-22-27/h6,8-15,18-19,27,30-32H,3-5,7,16-17,20-24H2,1-2H3,(H2,40,45)(H,41,49)(H,42,50)(H,43,48)(H,46,47)(H,51,52)/b8-6+/t27-,30-,31+,32+/m1/s1 ZWNYXQUNZTULFN-BIZYRGMISA-N 50168318 CHEMBL424823::[(15R,20S)-18-Carbamoylmethyl-10-[4-(hydroxy-methyl-phosphinoylmethyl)-phenyl]-14-(5-methyl-indol-1-ylmethyl)-20-oxo-8,17-di(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 16.2 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168318&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11181783 104053297 CHEMBL424823 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310343 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CC(O)=O)cc3)ccc2c1 InChI=1S/C39H47N5O8/c1-24-8-13-32-28(18-24)14-17-44(32)23-26-6-5-7-29(27-11-9-25(10-12-27)19-34(46)47)30(20-35(48)49)36(50)43-39(15-3-2-4-16-39)38(52)42-31(21-33(40)45)37(51)41-22-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,40,45)(H,41,51)(H,42,52)(H,43,50)(H,46,47)(H,48,49)/b7-5+/t26-,29-,30+,31+/m1/s1 WDSHANHIKDRCCI-AZSCFGFUSA-N 50168314 CHEMBL193015::[(7S,14R,18S)-18-Carbamoylmethyl-10-(4-carboxymethyl-phenyl)-14-(5-methyl-indol-1-ylmethyl)-17,20-dioxo-8-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 33 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168314&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11434036 104053293 CHEMBL193015 C03768 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310344 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(C)(O)=O)cc3)ccc2c1 InChI=1S/C39H50N5O8P/c1-25-9-14-33-29(19-25)15-18-44(33)23-27-7-6-8-30(28-12-10-26(11-13-28)24-53(2,51)52)31(20-35(46)47)36(48)43-39(16-4-3-5-17-39)38(50)42-32(21-34(40)45)37(49)41-22-27/h6,8-15,18-19,27,30-32H,3-5,7,16-17,20-24H2,1-2H3,(H2,40,45)(H,41,49)(H,42,50)(H,43,48)(H,46,47)(H,51,52)/b8-6+/t27-,30-,31+,32+/m1/s1 ZWNYXQUNZTULFN-BIZYRGMISA-N 50168318 CHEMBL424823::[(15R,20S)-18-Carbamoylmethyl-10-[4-(hydroxy-methyl-phosphinoylmethyl)-phenyl]-14-(5-methyl-indol-1-ylmethyl)-20-oxo-8,17-di(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 6.3 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168318&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11181783 104053297 CHEMBL424823 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310345 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(=O)Cc4ccccc4)cc3)ccc2c1 InChI=1S/C45H54N5O8P/c1-30-13-18-39-35(23-30)19-22-50(39)27-33-11-8-12-36(34-16-14-32(15-17-34)29-59(57,58)28-31-9-4-2-5-10-31)37(24-41(52)53)42(54)49-45(20-6-3-7-21-45)44(56)48-38(25-40(46)51)43(55)47-26-33/h2,4-5,8-10,12-19,22-23,33,36-38H,3,6-7,11,20-21,24-29H2,1H3,(H2,46,51)(H,47,55)(H,48,56)(H,49,54)(H,52,53)(H,57,58)/b12-8+/t33-,36-,37+,38+/m1/s1 WWHGZGAMKKXJAA-SSXRZIRRSA-N 50168317 CHEMBL193281::[(15R,20S)-10-[4-(Benzyl-hydroxy-phosphinoylmethyl)-phenyl]-18-carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-20-oxo-8,17-di(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 8.4 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168317&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11422983 104053296 CHEMBL193281 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50310346 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(cc3)C(C(O)=O)C(O)=O)ccc2c1 InChI=1S/C40H47N5O10/c1-23-8-13-31-27(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-26(12-10-25)34(37(51)52)38(53)54)29(19-33(47)48)35(49)44-40(15-3-2-4-16-40)39(55)43-30(20-32(41)46)36(50)42-21-24/h5,7-14,17-18,24,28-30,34H,2-4,6,15-16,19-22H2,1H3,(H2,41,46)(H,42,50)(H,43,55)(H,44,49)(H,47,48)(H,51,52)(H,53,54)/b7-5+/t24-,28-,29+,30+/m1/s1 ZUXPTLXJHBSAQT-YUAXJFSXSA-N 50168312 2-{4-[(16R,20S)-18-((S)-Carbamoylmethyl)-9-carboxymethyl-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl]-phenyl}-malonic acid::CHEMBL191728 Growth factor receptor-bound protein 2 Homo sapiens 3.3 ChEMBL 10.1021/jm050059m 10.7270/Q2V69J48 15943469 Kang, SU; Shi, ZD; Worthy, KM; Bindu, LK; Dharmawardana, PG; Choyke, SJ; Bottaro, DP; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168312&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11377706 104053291 CHEMBL191728 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50316364 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30-/m0/s1 ATTZUIWVKJIUFV-KYJUHHDHSA-N 50072862 CHEMBL117807::Phosphoric acid mono-[4-((S)-2-acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester::Phosphoric acid mono-[4-(2-acetylamino-2-{(S)-1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 47 ChEMBL 10.1021/jm050154v 10.7270/Q2513XRP 16078854 Kang, SU; Worthy, KM; Bindu, LK; Zhang, M; Yang, D; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072862&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987342 103966453 CHEMBL117807 C01167 ZINC27102270 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50316365 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CC(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C37H43N5O9/c38-30(43)22-29(32(46)39-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)41-36(51)37(17-4-1-5-18-37)42-33(47)28(40-34(48)35(49)50)20-23-13-15-24(16-14-23)21-31(44)45/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,38,43)(H,39,46)(H,40,48)(H,41,51)(H,42,47)(H,44,45)(H,49,50)/t28-,29-/m0/s1 XYXSUXVWOJXCIE-VMPREFPWSA-N 50085877 CHEMBL355066::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-carboxymethyl-phenyl)-ethyl]-oxalamic acid Growth factor receptor-bound protein 2 Homo sapiens 1000 ChEMBL 10.1021/jm050154v 10.7270/Q2513XRP 16078854 Kang, SU; Worthy, KM; Bindu, LK; Zhang, M; Yang, D; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085877&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10032662 103985287 CHEMBL355066 C03768 ZINC27992388 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50316366 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 ZOJQPGFTWKKVQO-NSOVKSMOSA-N 50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150 Growth factor receptor-bound protein 2 Homo sapiens 70.0 ChEMBL 10.1021/jm050154v 10.7270/Q2513XRP 16078854 Kang, SU; Worthy, KM; Bindu, LK; Zhang, M; Yang, D; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9896853 103985277 CHEMBL303150 ZINC95610086 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339374 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)C(O)=O)NC1=O)C(N)=O InChI=1S/C43H63N9O15S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(18-24)41(64)65)40(63)52-43(14-5-3-6-15-43)42(66)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-68(67)22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,66)(H,52,63)(H,57,58)(H,64,65)/t26-,27-,28-,29-,30-,68?/m0/s1 ZBNAOOPKCVUAHO-UHVQNBIWSA-N 50183413 CHEMBL382348::cyclo-(CH2-CO-Adi-Leu-(3'-CO2H-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 16000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183413&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408591 104067901 CHEMBL382348 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339375 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H64N10O13S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(43)18-24)40(63)52-42(14-5-3-6-15-42)41(64)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-66(65)22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22,43H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30-,66?/m0/s1 SXDWVMDSKSVHQA-WKBIZPDKSA-N 50183414 CHEMBL425761::cyclo-(CH2-CO-Adi-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 3900 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183414&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408540 104067902 CHEMBL425761 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339376 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(O)c2)NC1=O)C(N)=O InChI=1S/C42H63N9O14S/c1-23(2)17-26-39(62)49-27(18-24-12-13-30(52)31(53)19-24)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-66(65)22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,52-53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29+,66?/m0/s1 PASUFBYNMGEBTF-IDFZTNERSA-N 50183415 CHEMBL409145::cyclo-(CH2-CO-Adi-Leu-(3'-OH-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 550000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183415&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408125 104067903 CHEMBL409145 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339377 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C37H53N9O13S/c1-17(2)10-21-30(51)43-22(12-18-6-7-26(47)20(38)11-18)33(54)46-37(8-4-3-5-9-37)36(59)45-24(14-27(39)48)32(53)44-25(29(40)50)15-60-16-28(49)41-23(31(52)42-21)13-19(34(55)56)35(57)58/h6-7,11,17,19,21-25,47H,3-5,8-10,12-16,38H2,1-2H3,(H2,39,48)(H2,40,50)(H,41,49)(H,42,52)(H,43,51)(H,44,53)(H,45,59)(H,46,54)(H,55,56)(H,57,58)/t21-,22-,23-,24-,25-/m0/s1 IOFQQTJQYQEUFO-KEOOTSPTSA-N 50183416 CHEMBL202731::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 22500 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183416&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408456 104067904 CHEMBL202731 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339378 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)C(O)=O)NC1=O)C(N)=O InChI=1S/C43H63N9O14S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(18-24)41(64)65)40(63)52-43(14-5-3-6-15-43)42(66)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-67-22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,66)(H,52,63)(H,57,58)(H,64,65)/t26-,27-,28-,29-,30-/m0/s1 CYNBQCRABFNGLD-IIZANFQQSA-N 50183419 CHEMBL263566::cyclo-(CH2-CO-Adi-Leu-(3'-CO2H-Tyr)-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 88000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183419&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408439 104067907 CHEMBL263566 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339379 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(O)c2)NC1=O)C(N)=O InChI=1S/C42H63N9O14S/c1-23(2)17-26-39(62)49-27(18-24-12-13-30(52)31(53)19-24)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-66(65)22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,52-53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29-,66?/m0/s1 PASUFBYNMGEBTF-JNNTYAIASA-N 50183418 CHEMBL410470::cyclo-(CH2-CO-Adi-Leu-(3'-OH-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 87000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183418&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408543 104067906 CHEMBL410470 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339380 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C40H58N10O15S/c1-19(2)12-23-34(57)48-24(14-20-6-7-28(51)22(41)13-20)36(59)50-40(9-4-3-5-10-40)39(64)49-26(16-29(42)52)33(56)44-11-8-30(53)46-27(32(43)55)17-66(65)18-31(54)45-25(35(58)47-23)15-21(37(60)61)38(62)63/h6-7,13,19,21,23-27,51H,3-5,8-12,14-18,41H2,1-2H3,(H2,42,52)(H2,43,55)(H,44,56)(H,45,54)(H,46,53)(H,47,58)(H,48,57)(H,49,64)(H,50,59)(H,60,61)(H,62,63)/t23-,24-,25-,26-,27-,66?/m0/s1 JQFZLKBNGBDGFU-VHSVPJKWSA-N 50183417 CHEMBL383709::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-beta-Ala-Cys-(O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 360 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183417&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408552 104067905 CHEMBL383709 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339381 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)[N+]([O-])=O)NC1=O)C(N)=O InChI=1S/C42H62N10O15S/c1-23(2)17-26-39(62)49-27(18-24-12-13-31(53)30(19-24)52(65)66)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-68(67)22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29+,68?/m0/s1 BADSZEZHLCLEBB-JVLILADNSA-N 50183420 CHEMBL437126::cyclo-(CH2-CO-Adi-Leu-(3'-NO2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 265000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183420&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408574 104067908 CHEMBL437126 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339382 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)[N+]([O-])=O)NC1=O)C(N)=O InChI=1S/C42H62N10O14S/c1-23(2)17-26-39(62)49-27(18-24-12-13-31(53)30(19-24)52(65)66)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-67-22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29-/m0/s1 WUNPVRRZPDCVMX-ZIUUJSQJSA-N 50183422 CHEMBL381812::cyclo-(CH2-CO-Adi-Leu-(3'-NO2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide Growth factor receptor-bound protein 2 Homo sapiens 182000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183422&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408371 104067910 CHEMBL381812 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339383 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C37H53N9O14S/c1-17(2)10-21-30(51)43-22(12-18-6-7-26(47)20(38)11-18)33(54)46-37(8-4-3-5-9-37)36(59)45-24(14-27(39)48)32(53)44-25(29(40)50)15-61(60)16-28(49)41-23(31(52)42-21)13-19(34(55)56)35(57)58/h6-7,11,17,19,21-25,47H,3-5,8-10,12-16,38H2,1-2H3,(H2,39,48)(H2,40,50)(H,41,49)(H,42,52)(H,43,51)(H,44,53)(H,45,59)(H,46,54)(H,55,56)(H,57,58)/t21-,22-,23-,24-,25+,61?/m0/s1 VLWDBHGGUNWPLN-SELXPFGTSA-N 50183421 CHEMBL204668::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 200000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183421&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408645 104067909 CHEMBL204668 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339384 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)CCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C40H58N10O14S/c1-19(2)12-23-34(57)48-24(14-20-6-7-28(51)22(41)13-20)36(59)50-40(9-4-3-5-10-40)39(64)49-26(16-29(42)52)33(56)44-11-8-30(53)46-27(32(43)55)17-65-18-31(54)45-25(35(58)47-23)15-21(37(60)61)38(62)63/h6-7,13,19,21,23-27,51H,3-5,8-12,14-18,41H2,1-2H3,(H2,42,52)(H2,43,55)(H,44,56)(H,45,54)(H,46,53)(H,47,58)(H,48,57)(H,49,64)(H,50,59)(H,60,61)(H,62,63)/t23-,24-,25-,26-,27-/m0/s1 HTUOZMPJQLQORT-IRGGMKSGSA-N 50183423 CHEMBL204237::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-beta-Ala-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 1020 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183423&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408499 104067911 CHEMBL204237 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339385 COc1cc(C[C@@H]2NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC2=O)C(N)=O)ccc1O InChI=1S/C43H65N9O14S/c1-24(2)18-27-40(62)50-28(19-25-13-14-31(53)32(20-25)66-3)41(63)52-43(15-6-4-7-16-43)42(64)51-29(21-33(44)54)38(60)46-17-8-5-11-34(55)48-30(37(45)59)22-67(65)23-35(56)47-26(39(61)49-27)10-9-12-36(57)58/h13-14,20,24,26-30,53H,4-12,15-19,21-23H2,1-3H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30-,67?/m0/s1 KHKKTONKFOYPAS-SLQVUNOOSA-N 50183424 CHEMBL381813::cyclo-(CH2-CO-Adi-Leu-(3'-OMe-Tyr)-Ac6c-Asn-Ava-Cys(O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 97000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183424&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408514 104067912 CHEMBL381813 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339386 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O13S/c1-24(2)19-28-39(61)49-29(20-25-12-14-26(52)15-13-25)40(62)51-42(16-5-3-6-17-42)41(63)50-30(21-32(43)53)37(59)45-18-7-4-10-33(54)47-31(36(44)58)22-65(64)23-34(55)46-27(38(60)48-28)9-8-11-35(56)57/h12-15,24,27-31,52H,3-11,16-23H2,1-2H3,(H2,43,53)(H2,44,58)(H,45,59)(H,46,55)(H,47,54)(H,48,60)(H,49,61)(H,50,63)(H,51,62)(H,56,57)/t27-,28-,29-,30-,31+,65?/m0/s1 YNWUNFGKJHUKJS-BCSOHXHFSA-N 50183427 CHEMBL264656::cyclo-(CH2-CO-Adi-Leu-Tyr-Ac6c-Asn-Ava-Cys (O))-amide(S) Growth factor receptor-bound protein 2 Homo sapiens 1000000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183427&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408428 104067915 CHEMBL264656 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339387 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)[N+]([O-])=O)NC1=O)C(N)=O InChI=1S/C42H62N10O15S/c1-23(2)17-26-39(62)49-27(18-24-12-13-31(53)30(19-24)52(65)66)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-68(67)22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29-,68?/m0/s1 BADSZEZHLCLEBB-ZUIKHJCVSA-N 50183428 CHEMBL424855::cyclo-(CH2-CO-Adi-Leu-(3'-NO2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 25000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183428&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408585 104067916 CHEMBL424855 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339388 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H62N10O14S/c1-21(2)14-25-36(59)50-26(16-22-9-10-30(53)24(43)15-22)38(61)52-42(11-5-3-6-12-42)41(66)51-28(18-31(44)54)35(58)46-13-7-4-8-32(55)48-29(34(45)57)19-67-20-33(56)47-27(37(60)49-25)17-23(39(62)63)40(64)65/h9-10,15,21,23,25-29,53H,3-8,11-14,16-20,43H2,1-2H3,(H2,44,54)(H2,45,57)(H,46,58)(H,47,56)(H,48,55)(H,49,60)(H,50,59)(H,51,66)(H,52,61)(H,62,63)(H,64,65)/t25-,26-,27-,28-,29-/m0/s1 ORSHMSRLUFJYGO-ZIUUJSQJSA-N 50183426 CHEMBL262988::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 190 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183426&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408495 104067914 CHEMBL262988 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339389 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H62N10O15S/c1-21(2)14-25-36(59)50-26(16-22-9-10-30(53)24(43)15-22)38(61)52-42(11-5-3-6-12-42)41(66)51-28(18-31(44)54)35(58)46-13-7-4-8-32(55)48-29(34(45)57)19-68(67)20-33(56)47-27(37(60)49-25)17-23(39(62)63)40(64)65/h9-10,15,21,23,25-29,53H,3-8,11-14,16-20,43H2,1-2H3,(H2,44,54)(H2,45,57)(H,46,58)(H,47,56)(H,48,55)(H,49,60)(H,50,59)(H,51,66)(H,52,61)(H,62,63)(H,64,65)/t25-,26-,27-,28-,29+,68?/m0/s1 BKDUJUHYNZMWOZ-JVLILADNSA-N 50183430 CHEMBL205022::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 1550 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183430&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408601 104067918 CHEMBL205022 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339390 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C37H53N9O14S/c1-17(2)10-21-30(51)43-22(12-18-6-7-26(47)20(38)11-18)33(54)46-37(8-4-3-5-9-37)36(59)45-24(14-27(39)48)32(53)44-25(29(40)50)15-61(60)16-28(49)41-23(31(52)42-21)13-19(34(55)56)35(57)58/h6-7,11,17,19,21-25,47H,3-5,8-10,12-16,38H2,1-2H3,(H2,39,48)(H2,40,50)(H,41,49)(H,42,52)(H,43,51)(H,44,53)(H,45,59)(H,46,54)(H,55,56)(H,57,58)/t21-,22-,23-,24-,25-,61?/m0/s1 VLWDBHGGUNWPLN-XTRHMRTJSA-N 50183431 CHEMBL381980::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 9700 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183431&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408553 104067919 CHEMBL381980 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339391 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H64N10O13S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(43)18-24)40(63)52-42(14-5-3-6-15-42)41(64)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-66(65)22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22,43H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30+,66?/m0/s1 SXDWVMDSKSVHQA-VHIKPJTDSA-N 50183432 CHEMBL203840::cyclo-(CH2-CO-Adi-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 14000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183432&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408586 104067920 CHEMBL203840 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339392 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C40H58N10O15S/c1-19(2)12-23-34(57)48-24(14-20-6-7-28(51)22(41)13-20)36(59)50-40(9-4-3-5-10-40)39(64)49-26(16-29(42)52)33(56)44-11-8-30(53)46-27(32(43)55)17-66(65)18-31(54)45-25(35(58)47-23)15-21(37(60)61)38(62)63/h6-7,13,19,21,23-27,51H,3-5,8-12,14-18,41H2,1-2H3,(H2,42,52)(H2,43,55)(H,44,56)(H,45,54)(H,46,53)(H,47,58)(H,48,57)(H,49,64)(H,50,59)(H,60,61)(H,62,63)/t23-,24-,25-,26-,27+,66?/m0/s1 JQFZLKBNGBDGFU-ADYJZEDGSA-N 50183429 CHEMBL203512::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-beta-Ala-Cys (O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 11200 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183429&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408627 104067917 CHEMBL203512 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339393 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O12S/c1-24(2)19-28-39(61)49-29(20-25-12-14-26(52)15-13-25)40(62)51-42(16-5-3-6-17-42)41(63)50-30(21-32(43)53)37(59)45-18-7-4-10-33(54)47-31(36(44)58)22-64-23-34(55)46-27(38(60)48-28)9-8-11-35(56)57/h12-15,24,27-31,52H,3-11,16-23H2,1-2H3,(H2,43,53)(H2,44,58)(H,45,59)(H,46,55)(H,47,54)(H,48,60)(H,49,61)(H,50,63)(H,51,62)(H,56,57)/t27-,28-,29-,30-,31-/m0/s1 JGAIIUUEMGZEMM-QKUYTOGTSA-N 50183433 CHEMBL203579::cyclo-(CH2-CO-Adi-Leu-Tyr-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 93000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183433&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408550 104067921 CHEMBL203579 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339394 COc1cc(C[C@@H]2NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC2=O)C(N)=O)ccc1O InChI=1S/C43H65N9O14S/c1-24(2)18-27-40(62)50-28(19-25-13-14-31(53)32(20-25)66-3)41(63)52-43(15-6-4-7-16-43)42(64)51-29(21-33(44)54)38(60)46-17-8-5-11-34(55)48-30(37(45)59)22-67(65)23-35(56)47-26(39(61)49-27)10-9-12-36(57)58/h13-14,20,24,26-30,53H,4-12,15-19,21-23H2,1-3H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30+,67?/m0/s1 KHKKTONKFOYPAS-UOFHPKLCSA-N 50183435 CHEMBL438786::cyclo-(CH2-CO-Adi-Leu-(3'-OMe-Tyr)-Ac6c-Asn-Ava-Cys(O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens >1000000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183435&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408490 104067923 CHEMBL438786 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339395 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H64N10O12S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(43)18-24)40(63)52-42(14-5-3-6-15-42)41(64)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-65-22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22,43H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30-/m0/s1 ISKXEJSPGXQTHK-IIZANFQQSA-N 50183436 CHEMBL380964::cyclo-(CH2-CO-Adi-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 8900 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183436&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408636 104067924 CHEMBL380964 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339396 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O13S/c1-24(2)19-28-39(61)49-29(20-25-12-14-26(52)15-13-25)40(62)51-42(16-5-3-6-17-42)41(63)50-30(21-32(43)53)37(59)45-18-7-4-10-33(54)47-31(36(44)58)22-65(64)23-34(55)46-27(38(60)48-28)9-8-11-35(56)57/h12-15,24,27-31,52H,3-11,16-23H2,1-2H3,(H2,43,53)(H2,44,58)(H,45,59)(H,46,55)(H,47,54)(H,48,60)(H,49,61)(H,50,63)(H,51,62)(H,56,57)/t27-,28-,29-,30-,31-,65?/m0/s1 YNWUNFGKJHUKJS-RLESCGPSSA-N 50183434 CHEMBL379915::cyclo-(CH2-CO-Adi-Leu-Tyr-Ac6c-Asn-Ava-Cys (O))-amide(R) Growth factor receptor-bound protein 2 Homo sapiens 77000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183434&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408551 104067922 CHEMBL379915 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339397 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CS(=O)C[C@@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(c2)C(O)=O)NC1=O)C(N)=O InChI=1S/C43H63N9O15S/c1-23(2)17-27-39(62)50-28(19-24-12-13-31(53)25(18-24)41(64)65)40(63)52-43(14-5-3-6-15-43)42(66)51-29(20-32(44)54)37(60)46-16-7-4-10-33(55)48-30(36(45)59)21-68(67)22-34(56)47-26(38(61)49-27)9-8-11-35(57)58/h12-13,18,23,26-30,53H,3-11,14-17,19-22H2,1-2H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,66)(H,52,63)(H,57,58)(H,64,65)/t26-,27-,28-,29-,30+,68?/m0/s1 ZBNAOOPKCVUAHO-FMGSIJIOSA-N 50183438 CHEMBL381546::cyclo-(CH2-CO-Adi-Leu-(3'-CO2H-Tyr)-Ac6c-Asn-Ava-Cys(O))-amide (S) Growth factor receptor-bound protein 2 Homo sapiens 212000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183438&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408565 104067926 CHEMBL381546 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339398 COc1cc(C[C@@H]2NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC2=O)C(N)=O)ccc1O InChI=1S/C43H65N9O13S/c1-24(2)18-27-40(62)50-28(19-25-13-14-31(53)32(20-25)65-3)41(63)52-43(15-6-4-7-16-43)42(64)51-29(21-33(44)54)38(60)46-17-8-5-11-34(55)48-30(37(45)59)22-66-23-35(56)47-26(39(61)49-27)10-9-12-36(57)58/h13-14,20,24,26-30,53H,4-12,15-19,21-23H2,1-3H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,61)(H,50,62)(H,51,64)(H,52,63)(H,57,58)/t26-,27-,28-,29-,30-/m0/s1 UIISKLQGIQZAHU-IIZANFQQSA-N 50183437 CHEMBL438199::cyclo-(CH2-CO-Adi-Leu-(3'-OMe-Tyr)-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 245000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183437&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408513 104067925 CHEMBL438199 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339399 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(O)c2)NC1=O)C(N)=O InChI=1S/C42H63N9O13S/c1-23(2)17-26-39(62)49-27(18-24-12-13-30(52)31(53)19-24)40(63)51-42(14-5-3-6-15-42)41(64)50-28(20-32(43)54)37(60)45-16-7-4-10-33(55)47-29(36(44)59)21-65-22-34(56)46-25(38(61)48-26)9-8-11-35(57)58/h12-13,19,23,25-29,52-53H,3-11,14-18,20-22H2,1-2H3,(H2,43,54)(H2,44,59)(H,45,60)(H,46,56)(H,47,55)(H,48,61)(H,49,62)(H,50,64)(H,51,63)(H,57,58)/t25-,26-,27-,28-,29-/m0/s1 LVKKUFDTVPBMFD-ZIUUJSQJSA-N 50183439 CHEMBL381327::cyclo-(CH2-CO-Adi-Leu-(3'-OH-Tyr)-Ac6c-Asn-Ava-Cys)-amide Growth factor receptor-bound protein 2 Homo sapiens 135000 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183439&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44408542 104067927 CHEMBL381327 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50339400 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H62N10O15S/c1-21(2)14-25-36(59)50-26(16-22-9-10-30(53)24(43)15-22)38(61)52-42(11-5-3-6-12-42)41(66)51-28(18-31(44)54)35(58)46-13-7-4-8-32(55)48-29(34(45)57)19-68(67)20-33(56)47-27(37(60)49-25)17-23(39(62)63)40(64)65/h9-10,15,21,23,25-29,53H,3-8,11-14,16-20,43H2,1-2H3,(H2,44,54)(H2,45,57)(H,46,58)(H,47,56)(H,48,55)(H,49,60)(H,50,59)(H,51,66)(H,52,61)(H,62,63)(H,64,65)/t25-,26-,27-,28-,29-,68?/m0/s1 BKDUJUHYNZMWOZ-ZUIKHJCVSA-N 50183425 CHEMBL203761::cyclo-(CH2-CO-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Asn-Ava-Cys (O))-amide (R) Growth factor receptor-bound protein 2 Homo sapiens 58 ChEMBL 10.1021/jm050910x 10.7270/Q23R0SGX 16509576 Song, YL; Peach, ML; Roller, PP; Qiu, S; Wang, S; Long, YQ Graduate School of the Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183425&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11622149 104067913 CHEMBL203761 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356624 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](Cc2ccc(CP(O)(O)=O)cc2)NC(=O)Cn2cc(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@@H](Cc3ccc(CP(O)(O)=O)cc3)NC(=O)Cn3cc(CCCNC1=O)nn3)nn2 InChI=1S/C56H78N16O16P2/c57-45(73)27-43-49(77)59-23-7-9-39-30-72(70-68-39)32-48(76)62-42(26-36-13-17-38(18-14-36)34-90(86,87)88)52(80)66-56(21-5-2-6-22-56)54(82)64-44(28-46(58)74)50(78)60-24-8-10-40-29-71(69-67-40)31-47(75)61-41(25-35-11-15-37(16-12-35)33-89(83,84)85)51(79)65-55(53(81)63-43)19-3-1-4-20-55/h11-18,29-30,41-44H,1-10,19-28,31-34H2,(H2,57,73)(H2,58,74)(H,59,77)(H,60,78)(H,61,75)(H,62,76)(H,63,81)(H,64,82)(H,65,79)(H,66,80)(H2,83,84,85)(H2,86,87,88)/t41-,42-,43+,44+/m1/s1 FGRLLBKQHNTRTQ-QHQGJXSCSA-N 50193149 ({4-[(5'R,11'S,24'R,30'S)-11',30'-bis(carbamoylmethyl)-3',6',9',12',22',25',28',31'-octaoxo-24'-{[4-(phosphonomethyl)phenyl]methyl}dispiro[cyclohexane-1,8'-[1,4,7,10,13,18,19,20,23,26,29,32,37,38]tetradecaazatricyclo[34.2.1.1^{17,20}]tetracontane-27',1''-cyclohexane]-17'(40'),18',36'(39'),37'-tetraen-5'-ylmethyl]phenyl}methyl)phosphonic acid::CHEMBL385364 Growth factor receptor-bound protein 2 Homo sapiens >1000 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193149&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418278 104075715 CHEMBL385364 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356625 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(CP(O)(O)=O)cc2)NC(=O)Cn2cc(CCCNC1=O)nn2 InChI=1S/C28H39N8O8P/c29-23(37)14-22-25(39)30-12-4-5-20-15-36(35-34-20)16-24(38)31-21(13-18-6-8-19(9-7-18)17-45(42,43)44)26(40)33-28(27(41)32-22)10-2-1-3-11-28/h6-9,15,21-22H,1-5,10-14,16-17H2,(H2,29,37)(H,30,39)(H,31,38)(H,32,41)(H,33,40)(H2,42,43,44)/t21-,22-/m0/s1 JEJIUKMBFQBJQM-VXKWHMMOSA-N 50193150 ({4-[(5S,11S)-11-(carbamoylmethyl)-3,6,9,12-tetraoxo-1,4,7,10,13,18,19-heptaazaspiro[bicyclo[15.2.1]icosane-8,1'-cyclohexane]-17(20),18-dien-5-ylmethyl]phenyl}methyl)phosphonic acid::CHEMBL385458 Growth factor receptor-bound protein 2 Homo sapiens 230 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193150&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418275 104075716 CHEMBL385458 ZINC36761377 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356626 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(CP(O)(O)=O)cc2)NC(=O)Cn2cc(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(=O)Cn3cc(CCCNC1=O)nn3)nn2 InChI=1S/C56H78N16O16P2/c57-45(73)27-43-49(77)59-23-7-9-39-30-72(70-68-39)32-48(76)62-42(26-36-13-17-38(18-14-36)34-90(86,87)88)52(80)66-56(21-5-2-6-22-56)54(82)64-44(28-46(58)74)50(78)60-24-8-10-40-29-71(69-67-40)31-47(75)61-41(25-35-11-15-37(16-12-35)33-89(83,84)85)51(79)65-55(53(81)63-43)19-3-1-4-20-55/h11-18,29-30,41-44H,1-10,19-28,31-34H2,(H2,57,73)(H2,58,74)(H,59,77)(H,60,78)(H,61,75)(H,62,76)(H,63,81)(H,64,82)(H,65,79)(H,66,80)(H2,83,84,85)(H2,86,87,88)/t41-,42-,43-,44-/m0/s1 FGRLLBKQHNTRTQ-ITMZJIMRSA-N 50193151 ({4-[(5'S,11'S,24'S,30'S)-11',30'-bis(carbamoylmethyl)-3',6',9',12',22',25',28',31'-octaoxo-24'-{[4-(phosphonomethyl)phenyl]methyl}dispiro[cyclohexane-1,8'-[1,4,7,10,13,18,19,20,23,26,29,32,37,38]tetradecaazatricyclo[34.2.1.1^{17,20}]tetracontane-27',1''-cyclohexane]-17'(40'),18',36'(39'),37'-tetraen-5'-ylmethyl]phenyl}methyl)phosphonic acid::CHEMBL437910 Growth factor receptor-bound protein 2 Homo sapiens 1.8 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193151&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418277 104075717 CHEMBL437910 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356627 CCCCCNC(=O)[C@H](CC(N)=O)NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)Cn1cc(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(CP(O)(O)=O)cc2)NC(C)=O)nn1 InChI=1S/C56H83N13O16P2/c1-3-4-11-26-59-49(74)44(30-46(57)71)63-54(79)56(24-9-6-10-25-56)66-52(77)43(29-38-16-20-40(21-17-38)35-87(83,84)85)62-48(73)33-69-32-41(67-68-69)13-12-27-60-50(75)45(31-47(58)72)64-53(78)55(22-7-5-8-23-55)65-51(76)42(61-36(2)70)28-37-14-18-39(19-15-37)34-86(80,81)82/h14-21,32,42-45H,3-13,22-31,33-35H2,1-2H3,(H2,57,71)(H2,58,72)(H,59,74)(H,60,75)(H,61,70)(H,62,73)(H,63,79)(H,64,78)(H,65,76)(H,66,77)(H2,80,81,82)(H2,83,84,85)/t42-,43-,44-,45-/m0/s1 OBIHYPWJWZYHKY-HRBFTXTFSA-N 50193153 ({4-[(2S)-2-[(1-{[(1S)-2-carbamoyl-1-({3-[1-({[(1S)-1-[(1-{[(1S)-2-carbamoyl-1-(pentylcarbamoyl)ethyl]carbamoyl}cyclohexyl)carbamoyl]-2-[4-(phosphonomethyl)phenyl]ethyl]carbamoyl}methyl)-1H-1,2,3-triazol-4-yl]propyl}carbamoyl)ethyl]carbamoyl}cyclohexyl)carbamoyl]-2-acetamidoethyl]phenyl}methyl)phosphonic acid::CHEMBL427641 Growth factor receptor-bound protein 2 Homo sapiens 1.1 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193153&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418279 104075719 CHEMBL427641 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356628 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)CN=[N+]=[N-])C(=O)NCCCC#C InChI=1S/C28H39N8O8P/c1-2-3-7-14-31-25(39)22(16-23(29)37)34-27(41)28(12-5-4-6-13-28)35-26(40)21(33-24(38)17-32-36-30)15-19-8-10-20(11-9-19)18-45(42,43)44/h1,8-11,21-22H,3-7,12-18H2,(H2,29,37)(H,31,39)(H,33,38)(H,34,41)(H,35,40)(H2,42,43,44)/t21-,22-/m0/s1 YXVHLEHNODYNLL-VXKWHMMOSA-N 50193152 (13S,20S)-4-((S)-3-(1-(((S)-4-amino-1,4-dioxo-1-(pent-4-ynylamino)butan-2-yl)carbamoyl)cyclohexylamino)-2-(2-azidoacetamido)-3-oxopropyl)benzylphosphonic acid::CHEMBL439177 Growth factor receptor-bound protein 2 Homo sapiens >1000 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193152&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418274 104075718 CHEMBL439177 ZINC49817668 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50356629 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](Cc2ccc(CP(O)(O)=O)cc2)NC(=O)Cn2cc(CCCNC1=O)nn2 InChI=1S/C28H39N8O8P/c29-23(37)14-22-25(39)30-12-4-5-20-15-36(35-34-20)16-24(38)31-21(13-18-6-8-19(9-7-18)17-45(42,43)44)26(40)33-28(27(41)32-22)10-2-1-3-11-28/h6-9,15,21-22H,1-5,10-14,16-17H2,(H2,29,37)(H,30,39)(H,31,38)(H,32,41)(H,33,40)(H2,42,43,44)/t21-,22+/m1/s1 JEJIUKMBFQBJQM-YADHBBJMSA-N 50193154 ({4-[(5R,11S)-11-(carbamoylmethyl)-3,6,9,12-tetraoxo-1,4,7,10,13,18,19-heptaazaspiro[bicyclo[15.2.1]icosane-8,1'-cyclohexane]-17(20),18-dien-5-ylmethyl]phenyl}methyl)phosphonic acid::CHEMBL385459 Growth factor receptor-bound protein 2 Homo sapiens >1000 ChEMBL 10.1016/j.bmcl.2006.08.004 10.7270/Q2WM1D1P 16908148 Choi, WJ; Shi, ZD; Worthy, KM; Bindu, L; Karki, RG; Nicklaus, MC; Fisher, RJ; Burke, TR NIH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193154&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44418276 104075720 CHEMBL385459 ZINC49780098 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50365559 CC(C)[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O InChI=1S/C55H94N20O11/c1-30(2)41(66-32(5)76)51(85)74-28-13-21-40(74)50(84)73-27-11-19-38(73)48(82)72-26-10-18-37(72)47(81)70-42(31(3)4)52(86)75-29-12-20-39(75)49(83)71-25-9-17-36(71)46(80)69-35(16-8-24-65-55(61)62)45(79)68-34(15-7-23-64-54(59)60)44(78)67-33(43(56)77)14-6-22-63-53(57)58/h30-31,33-42H,6-29H2,1-5H3,(H2,56,77)(H,66,76)(H,67,78)(H,68,79)(H,69,80)(H,70,81)(H4,57,58,63)(H4,59,60,64)(H4,61,62,65)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m0/s1 RECFOXLRMYMGNL-NUDUWCFGSA-N 50198876 Ac-VPPPVPPRRR-NH2::CHEMBL390420 Growth factor receptor-bound protein 2 Homo sapiens 3670 ChEMBL 10.1016/j.bmc.2006.11.002 10.7270/Q29W0F50 17113302 Jacquot, Y; Broutin, I; Miclet, E; Nicaise, M; Lequin, O; Goasdoue, N; Joss, C; Karoyan, P; Desmadril, M; Ducruix, A; Lavielle, S Université Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198876&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 23585880 104079695 CHEMBL390420 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50365561 CC(C)[C@H](N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)N1CCCC1C(=O)N[C@@H](C(C)C)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O InChI=1S/C53H91N19O11/c1-29(2)39(54)48(80)71-27-11-19-37(71)47(79)70-26-10-18-36(70)45(77)69-25-9-17-35(69)44(76)67-40(30(3)4)49(81)72-28-12-20-38(72)46(78)68-24-8-16-34(68)43(75)65-32(14-6-22-62-52(57)58)41(73)64-31(13-5-21-61-51(55)56)42(74)66-33(50(82)83)15-7-23-63-53(59)60/h29-40H,5-28,54H2,1-4H3,(H,64,73)(H,65,75)(H,66,74)(H,67,76)(H,82,83)(H4,55,56,61)(H4,57,58,62)(H4,59,60,63)/t31-,32-,33-,34?,35?,36?,37?,38?,39-,40-/m0/s1 KDEHBKGSNFLJSF-XRIARVQLSA-N 50198878 CHEMBL437932::H-VPPPVPPRRR-OH Growth factor receptor-bound protein 2 Homo sapiens 38150 ChEMBL 10.1016/j.bmc.2006.11.002 10.7270/Q29W0F50 17113302 Jacquot, Y; Broutin, I; Miclet, E; Nicaise, M; Lequin, O; Goasdoue, N; Joss, C; Karoyan, P; Desmadril, M; Ducruix, A; Lavielle, S Université Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198878&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44428433 104079697 CHEMBL437932 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50365562 CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC(C)[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O InChI=1S/C54H91N19O11/c1-30(2)40(55)49(81)71-27-10-17-37(71)47(79)69-25-8-16-36(69)46(78)70-26-9-19-39(70)48(80)73-29-20-31(3)41(73)50(82)72-28-11-18-38(72)45(77)68-24-7-15-35(68)44(76)66-33(13-5-22-63-53(58)59)42(74)65-32(12-4-21-62-52(56)57)43(75)67-34(51(83)84)14-6-23-64-54(60)61/h30-41H,4-29,55H2,1-3H3,(H,65,74)(H,66,76)(H,67,75)(H,83,84)(H4,56,57,62)(H4,58,59,63)(H4,60,61,64)/t31?,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-/m0/s1 GDJOIMSLBNQXME-SEEGXZIYSA-N 50198879 CHEMBL439045::H-VPPPP(CH3)PPRRR-OH Growth factor receptor-bound protein 2 Homo sapiens 11600 ChEMBL 10.1016/j.bmc.2006.11.002 10.7270/Q29W0F50 17113302 Jacquot, Y; Broutin, I; Miclet, E; Nicaise, M; Lequin, O; Goasdoue, N; Joss, C; Karoyan, P; Desmadril, M; Ducruix, A; Lavielle, S Université Pierre et Marie Curie-Paris 6 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198879&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44428435 104079698 CHEMBL439045 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379262 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)S(=O)(=O)CCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C43H52N5O11PS/c44-38(49)28-37(41(53)45-21-6-9-31-16-17-34-10-4-5-11-35(34)25-31)46-42(54)43(19-22-48(23-20-43)61(58,59)24-18-30-7-2-1-3-8-30)47-40(52)36(27-39(50)51)26-32-12-14-33(15-13-32)29-60(55,56)57/h1-5,7-8,10-17,25,36-37H,6,9,18-24,26-29H2,(H2,44,49)(H,45,53)(H,46,54)(H,47,52)(H,50,51)(H2,55,56,57)/t36-,37+/m1/s1 YMLAPUPTQSWUIJ-AARKOHAPSA-N 50208562 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(phenethylsulfonyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL426733 Growth factor receptor-bound protein 2 Homo sapiens 2140 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208562&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420977 104085621 CHEMBL426733 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379263 Cc1ccc2n(CCC(=O)N3CCC(CC3)(NC(=O)[C@@H](CC(O)=O)Cc3ccc(CP(O)(O)=O)cc3)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc3ccc4ccccc4c3)ccc2c1 InChI=1S/C47H55N6O10P/c1-31-8-15-40-37(25-31)16-21-52(40)22-17-42(55)53-23-18-47(19-24-53,51-44(58)38(28-43(56)57)27-33-9-11-34(12-10-33)30-64(61,62)63)46(60)50-39(29-41(48)54)45(59)49-20-4-5-32-13-14-35-6-2-3-7-36(35)26-32/h2-3,6-16,21,25-26,38-39H,4-5,17-20,22-24,27-30H2,1H3,(H2,48,54)(H,49,59)(H,50,60)(H,51,58)(H,56,57)(H2,61,62,63)/t38-,39+/m1/s1 RQRRMQVQIOYEMU-RGULYWFUSA-N 50208563 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(3-(5-methyl-1H-indol-1-yl)propanoyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL376024 Growth factor receptor-bound protein 2 Homo sapiens 458 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208563&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420975 104085622 CHEMBL376024 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379264 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)CCCCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C46H56N5O10P/c47-40(52)30-39(44(57)48-24-8-12-33-20-21-36-13-5-6-14-37(36)27-33)49-45(58)46(22-25-51(26-23-46)41(53)15-7-4-11-32-9-2-1-3-10-32)50-43(56)38(29-42(54)55)28-34-16-18-35(19-17-34)31-62(59,60)61/h1-3,5-6,9-10,13-14,16-21,27,38-39H,4,7-8,11-12,15,22-26,28-31H2,(H2,47,52)(H,48,57)(H,49,58)(H,50,56)(H,54,55)(H2,59,60,61)/t38-,39+/m1/s1 RDNVRVNSUUMJFQ-RGULYWFUSA-N 50208565 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(5-phenylpentanoyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL222550 Growth factor receptor-bound protein 2 Homo sapiens 2180 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208565&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420974 104085624 CHEMBL222550 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379265 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)OCCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C44H52N5O11P/c45-38(50)28-37(41(54)46-21-6-9-31-16-17-34-10-4-5-11-35(34)25-31)47-42(55)44(19-22-49(23-20-44)43(56)60-24-18-30-7-2-1-3-8-30)48-40(53)36(27-39(51)52)26-32-12-14-33(15-13-32)29-61(57,58)59/h1-5,7-8,10-17,25,36-37H,6,9,18-24,26-29H2,(H2,45,50)(H,46,54)(H,47,55)(H,48,53)(H,51,52)(H2,57,58,59)/t36-,37+/m1/s1 GJDWMFBZQRYJAV-AARKOHAPSA-N 50208564 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(phenethoxycarbonyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL375580 Growth factor receptor-bound protein 2 Homo sapiens 36 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208564&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420972 104085623 CHEMBL375580 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379266 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)CCCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C45H54N5O10P/c46-39(51)29-38(43(56)47-23-7-11-32-19-20-35-12-4-5-13-36(35)26-32)48-44(57)45(21-24-50(25-22-45)40(52)14-6-10-31-8-2-1-3-9-31)49-42(55)37(28-41(53)54)27-33-15-17-34(18-16-33)30-61(58,59)60/h1-5,8-9,12-13,15-20,26,37-38H,6-7,10-11,14,21-25,27-30H2,(H2,46,51)(H,47,56)(H,48,57)(H,49,55)(H,53,54)(H2,58,59,60)/t37-,38+/m1/s1 CSYDRLPRAXGORY-AMAPPZPBSA-N 50208566 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(4-phenylbutanoyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL375797 Growth factor receptor-bound protein 2 Homo sapiens 27 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208566&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420973 104085625 CHEMBL375797 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379267 COCCOC(=O)N1CCC(CC1)(NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C39H50N5O12P/c1-55-19-20-56-38(51)44-17-14-39(15-18-44,43-35(48)31(23-34(46)47)22-27-8-10-28(11-9-27)25-57(52,53)54)37(50)42-32(24-33(40)45)36(49)41-16-4-5-26-12-13-29-6-2-3-7-30(29)21-26/h2-3,6-13,21,31-32H,4-5,14-20,22-25H2,1H3,(H2,40,45)(H,41,49)(H,42,50)(H,43,48)(H,46,47)(H2,52,53,54)/t31-,32+/m1/s1 AUDIQCCWEQPRPG-ZWXJPIIXSA-N 50208568 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-((2-methoxyethoxy)carbonyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL222982 Growth factor receptor-bound protein 2 Homo sapiens 202 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208568&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420970 104085627 CHEMBL222982 ZINC95606996 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379268 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)OCc1ccc(cc1)C(O)=O)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C44H50N5O13P/c45-37(50)25-36(40(54)46-19-3-4-28-11-14-32-5-1-2-6-34(32)22-28)47-42(57)44(17-20-49(21-18-44)43(58)62-26-30-12-15-33(16-13-30)41(55)56)48-39(53)35(24-38(51)52)23-29-7-9-31(10-8-29)27-63(59,60)61/h1-2,5-16,22,35-36H,3-4,17-21,23-27H2,(H2,45,50)(H,46,54)(H,47,57)(H,48,53)(H,51,52)(H,55,56)(H2,59,60,61)/t35-,36+/m1/s1 NBAXFTCVRPLXBN-XDSPJLLDSA-N 50208567 4-((4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-4-((R)-2-(4-(phosphonomethyl)benzyl)-3-carboxypropanamido)piperidine-1-carbonyloxy)methyl)benzoic acid::CHEMBL374029 Growth factor receptor-bound protein 2 Homo sapiens 871 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208567&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420978 104085626 CHEMBL374029 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379269 COC(=O)N1CCC(CC1)(NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C37H46N5O11P/c1-53-36(49)42-17-14-37(15-18-42,41-33(46)29(21-32(44)45)20-25-8-10-26(11-9-25)23-54(50,51)52)35(48)40-30(22-31(38)43)34(47)39-16-4-5-24-12-13-27-6-2-3-7-28(27)19-24/h2-3,6-13,19,29-30H,4-5,14-18,20-23H2,1H3,(H2,38,43)(H,39,47)(H,40,48)(H,41,46)(H,44,45)(H2,50,51,52)/t29-,30+/m1/s1 ZZBAWCBCWCEDEZ-IHLOFXLRSA-N 50208570 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(methoxycarbonyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL222733 Growth factor receptor-bound protein 2 Homo sapiens 106 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208570&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420969 104085629 CHEMBL222733 ZINC95606992 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379270 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)NCCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C44H53N6O10P/c45-38(51)28-37(41(55)46-21-6-9-31-16-17-34-10-4-5-11-35(34)25-31)48-42(56)44(19-23-50(24-20-44)43(57)47-22-18-30-7-2-1-3-8-30)49-40(54)36(27-39(52)53)26-32-12-14-33(15-13-32)29-61(58,59)60/h1-5,7-8,10-17,25,36-37H,6,9,18-24,26-29H2,(H2,45,51)(H,46,55)(H,47,57)(H,48,56)(H,49,54)(H,52,53)(H2,58,59,60)/t36-,37+/m1/s1 LJSJAGQZTSOEQD-AARKOHAPSA-N 50208569 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(phenethylcarbamoyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL373585 Growth factor receptor-bound protein 2 Homo sapiens 272 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208569&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420976 104085628 CHEMBL373585 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50379271 NC(=O)C[C@H](NC(=O)C1(CCN(CC1)C(=O)OCc1ccccc1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C43H50N5O11P/c44-37(49)26-36(40(53)45-20-6-9-29-16-17-33-10-4-5-11-34(33)23-29)46-41(54)43(18-21-48(22-19-43)42(55)59-27-31-7-2-1-3-8-31)47-39(52)35(25-38(50)51)24-30-12-14-32(15-13-30)28-60(56,57)58/h1-5,7-8,10-17,23,35-36H,6,9,18-22,24-28H2,(H2,44,49)(H,45,53)(H,46,54)(H,47,52)(H,50,51)(H2,56,57,58)/t35-,36+/m1/s1 CDFBILCSLIXYOV-XDSPJLLDSA-N 50208571 (R)-4-(4-(((S)-4-amino-1-(3-(naphthalen-2-yl)propylamino)-1,4-dioxobutan-2-yl)carbamoyl)-1-(benzyloxycarbonyl)piperidin-4-ylamino)-3-(4-(phosphonomethyl)benzyl)-4-oxobutanoic acid::CHEMBL374333 Growth factor receptor-bound protein 2 Homo sapiens 320 ChEMBL 10.1021/jm0614073 10.7270/Q29P31BB 17371004 Kang, SU; Choi, WJ; Oishi, S; Lee, K; Karki, RG; Worthy, KM; Bindu, LK; Nicklaus, MC; Fisher, RJ; Burke, TR National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208571&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44420971 104085630 CHEMBL374333 ZINC95612707 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50423728 C[C@@H](O)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(CC(O)=O)cc2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)CSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C69H82N14O20S/c1-36(84)59-68(102)80-50(27-38-13-6-3-7-14-38)69(103)83-24-10-17-52(83)67(101)81-51(60(71)94)34-104-35-55(87)75-47(30-42-29-41-15-8-9-16-43(41)73-42)64(98)77-46(25-37-11-4-2-5-12-37)63(97)76-44(22-23-56(88)89)61(95)72-33-54(86)74-45(26-39-18-20-40(21-19-39)28-57(90)91)62(96)79-49(32-58(92)93)65(99)78-48(31-53(70)85)66(100)82-59/h2-9,11-16,18-21,29,36,44-52,59,73,84H,10,17,22-28,30-35H2,1H3,(H2,70,85)(H2,71,94)(H,72,95)(H,74,86)(H,75,87)(H,76,97)(H,77,98)(H,78,99)(H,79,96)(H,80,102)(H,81,101)(H,82,100)(H,88,89)(H,90,91)(H,92,93)/t36-,44+,45+,46+,47+,48+,49+,50+,51+,52+,59+/m1/s1 PCZJPLQNPZHTJQ-BVCATKTLSA-N 50124405 CHEMBL3623449 Growth factor receptor-bound protein 2 Homo sapiens 440000 ChEMBL 10.1021/acs.jmedchem.5b00609 10.7270/Q23X88GG 26359549 Watson, GM; Gunzburg, MJ; Ambaye, ND; Lucas, WA; Traore, DA; Kulkarni, K; Cergol, KM; Payne, RJ; Panjikar, S; Pero, SC; Perlmutter, P; Wilce, MC; Wilce, JA The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124405&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 122192500 321902140 CHEMBL3623449 C03768 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50423731 C[C@@H](O)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(cc2)C(O)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)CSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C68H80N14O20S/c1-35(83)57-66(99)79-49(27-37-13-6-3-7-14-37)67(100)82-24-10-17-51(82)65(98)80-50(58(70)91)33-103-34-54(86)74-46(29-41-28-40-15-8-9-16-42(40)72-41)62(95)76-45(25-36-11-4-2-5-12-36)61(94)75-43(22-23-55(87)88)59(92)71-32-53(85)73-44(26-38-18-20-39(21-19-38)68(101)102)60(93)78-48(31-56(89)90)63(96)77-47(30-52(69)84)64(97)81-57/h2-9,11-16,18-21,28,35,43-51,57,72,83H,10,17,22-27,29-34H2,1H3,(H2,69,84)(H2,70,91)(H,71,92)(H,73,85)(H,74,86)(H,75,94)(H,76,95)(H,77,96)(H,78,93)(H,79,99)(H,80,98)(H,81,97)(H,87,88)(H,89,90)(H,101,102)/t35-,43+,44+,45+,46+,47+,48+,49+,50+,51+,57+/m1/s1 QKXUQASQZXYDCF-NOLDGVLCSA-N 50124406 CHEMBL3623450 Growth factor receptor-bound protein 2 Homo sapiens 560000 ChEMBL 10.1021/acs.jmedchem.5b00609 10.7270/Q23X88GG 26359549 Watson, GM; Gunzburg, MJ; Ambaye, ND; Lucas, WA; Traore, DA; Kulkarni, K; Cergol, KM; Payne, RJ; Panjikar, S; Pero, SC; Perlmutter, P; Wilce, MC; Wilce, JA The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124406&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 122192501 321902141 CHEMBL3623450 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50423737 C[C@@H](O)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)CSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C67H80N14O19S/c1-35(82)57-66(99)78-49(27-37-13-6-3-7-14-37)67(100)81-24-10-17-51(81)65(98)79-50(58(69)91)33-101-34-54(86)73-46(29-40-28-39-15-8-9-16-42(39)71-40)62(95)75-45(25-36-11-4-2-5-12-36)61(94)74-43(22-23-55(87)88)59(92)70-32-53(85)72-44(26-38-18-20-41(83)21-19-38)60(93)77-48(31-56(89)90)63(96)76-47(30-52(68)84)64(97)80-57/h2-9,11-16,18-21,28,35,43-51,57,71,82-83H,10,17,22-27,29-34H2,1H3,(H2,68,84)(H2,69,91)(H,70,92)(H,72,85)(H,73,86)(H,74,94)(H,75,95)(H,76,96)(H,77,93)(H,78,99)(H,79,98)(H,80,97)(H,87,88)(H,89,90)/t35-,43+,44+,45+,46+,47+,48+,49+,50+,51+,57+/m1/s1 VACYSOBRJYAGAW-NOLDGVLCSA-N 50124407 CHEMBL3623448 Growth factor receptor-bound protein 2 Homo sapiens 200000 ChEMBL 10.1021/acs.jmedchem.5b00609 10.7270/Q23X88GG 26359549 Watson, GM; Gunzburg, MJ; Ambaye, ND; Lucas, WA; Traore, DA; Kulkarni, K; Cergol, KM; Payne, RJ; Panjikar, S; Pero, SC; Perlmutter, P; Wilce, MC; Wilce, JA The University of Sydney http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124407&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 122192499 321902142 CHEMBL3623448 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50534379 Cc1ccc(OC(C)(C)C(=O)N[C@@H](Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@](C)(Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@H](CC(N)=O)C(N)=O)c(c1)\N=N\c1ccccc1 InChI=1S/C40H47N7O14P2/c1-24-10-19-33(30(20-24)47-46-27-8-6-5-7-9-27)59-39(2,3)37(51)44-32(21-25-11-15-28(16-12-25)60-62(53,54)55)36(50)45-40(4,38(52)43-31(35(42)49)22-34(41)48)23-26-13-17-29(18-14-26)61-63(56,57)58/h5-20,31-32H,21-23H2,1-4H3,(H2,41,48)(H2,42,49)(H,43,52)(H,44,51)(H,45,50)(H2,53,54,55)(H2,56,57,58)/b47-46+/t31-,32-,40-/m0/s1 DTESKLJFPIJUEW-GXEXKBTISA-N 50300042 4-[(2S)-2-{[(1S)-1-{[(1S)-1,2-dicarbamoylethyl]carbamoyl}-1-{[4-(phosphonooxy)phenyl]methyl}ethyl]carbamoyl}-2-(2-methyl-2-{4-methyl-2-[(E)-2-phenyldiazen-1-yl]phenoxy}propanamido)ethyl]phenoxyphosphonic acid::CHEMBL582892 Growth factor receptor-bound protein 2 Homo sapiens 11 ChEMBL 10.1016/j.ejmech.2009.10.003 10.7270/Q21C1WZD 19906464 Courme, C; Gresh, N; Vidal, M; Lenoir, C; Garbay, C; Florent, JC; Bertounesque, E CNRS UMR 176 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300042&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45482942 104154403 CHEMBL582892 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50534380 NC(=O)CNc1nc(Nc2ccc(OP([O-])([O-])=O)cc2)nc(n1)-c1ccccc1Oc1ccc(OP([O-])([O-])=O)cc1 InChI=1S/C23H22N6O10P2/c24-20(30)13-25-22-27-21(28-23(29-22)26-14-5-7-16(8-6-14)38-40(31,32)33)18-3-1-2-4-19(18)37-15-9-11-17(12-10-15)39-41(34,35)36/h1-12H,13H2,(H2,24,30)(H2,31,32,33)(H2,34,35,36)(H2,25,26,27,28,29)/p-4 DYTNXJPDDLDTDP-UHFFFAOYSA-J 50300043 CHEMBL573405::Sodium 2-(4-(2-(4-phosphonatooxyphenoxy)phenyl)-6-(4-phosphonatooxyphenylamino)-1,3,5-triazin-2-ylamino)acetamide Growth factor receptor-bound protein 2 Homo sapiens 2.65E5 ChEMBL 10.1016/j.ejmech.2009.10.003 10.7270/Q21C1WZD 19906464 Courme, C; Gresh, N; Vidal, M; Lenoir, C; Garbay, C; Florent, JC; Bertounesque, E CNRS UMR 176 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300043&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 91934132 104154404 CHEMBL573405 ZINC49695387 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622867 OC(=O)C[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C36H44N3O10P/c40-31(41)21-28(20-24-13-15-25(16-14-24)23-50(47,48)49)33(44)39-36(17-4-1-5-18-36)35(46)38-30(22-32(42)43)34(45)37-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H,37,45)(H,38,46)(H,39,44)(H,40,41)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1 QBSUVBVVFJXUOM-DGPALRBDSA-N 50336688 CHEMBL1672710::N2-{[1-({(2R)-2-carboxymethyl-3-[4-phosphonomethyl)phenyl]propanoyl}amino)cyclohexyl]carbonyl}-N1-[3-(1-naphthyl)propyl]-L-aspartamide Growth factor receptor-bound protein 2 Homo sapiens 8 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336688&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321378 125086790 CHEMBL1672710 ZINC72121207 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622868 CCCC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCCN1CCNC1=O InChI=1S/C18H27N4O7P/c1-2-3-16(23)21-15(17(24)19-8-10-22-11-9-20-18(22)25)12-13-4-6-14(7-5-13)29-30(26,27)28/h4-7,15H,2-3,8-12H2,1H3,(H,19,24)(H,20,25)(H,21,23)(H2,26,27,28)/t15-/m0/s1 HHRWSMRQSIBQLU-HNNXBMFYSA-N 50336689 CHEMBL1672702::N-Butyryl-N-[2-(2-oxoimidazolidin-1-yl)ethyl]-O-phosphono-L-tyrosinamide Growth factor receptor-bound protein 2 Homo sapiens 1330000 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336689&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 51002712 125086791 CHEMBL1672702 C01167 ZINC66098059 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622869 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCN2CCCNC2=O)CCCCC1 InChI=1S/C23H35N4O7P/c1-17(28)25-20(16-18-6-8-19(9-7-18)34-35(31,32)33)21(29)26-23(10-3-2-4-11-23)12-15-27-14-5-13-24-22(27)30/h6-9,20H,2-5,10-16H2,1H3,(H,24,30)(H,25,28)(H,26,29)(H2,31,32,33)/t20-/m0/s1 SSPVTCGLEAZMAT-FQEVSTJZSA-N 50336690 CHEMBL1672709::N-Acetyl-N-{1-[2-(2-oxotetrahydropyrimidin-1(2H)-yl)ethyl]cyclohexyl}-O-phosphono-L-tyrosinamide Growth factor receptor-bound protein 2 Homo sapiens 314000 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336690&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 51002754 125086792 CHEMBL1672709 C01167 ZINC66074861 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622870 CC(=O)NC(Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCCCN1CCCNC1=O InChI=1S/C18H27N4O7P/c1-13(23)21-16(12-14-4-6-15(7-5-14)29-30(26,27)28)17(24)19-8-2-10-22-11-3-9-20-18(22)25/h4-7,16H,2-3,8-12H2,1H3,(H,19,24)(H,20,25)(H,21,23)(H2,26,27,28) RIBDYTODEHUADD-UHFFFAOYSA-N 50336691 CHEMBL1672708::N-Acetyl-N-[3-(2-oxotetrahydropyrimidin-1(2H)-yl)propyl]-O-phosphono-D,L-tyrosinamide Growth factor receptor-bound protein 2 Homo sapiens 2307000 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336691&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 51002753 125086793 CHEMBL1672708 ZINC66076105 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622871 CCCC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCCCN1CCCNC1=O InChI=1S/C20H31N4O7P/c1-2-5-18(25)23-17(14-15-6-8-16(9-7-15)31-32(28,29)30)19(26)21-10-3-12-24-13-4-11-22-20(24)27/h6-9,17H,2-5,10-14H2,1H3,(H,21,26)(H,22,27)(H,23,25)(H2,28,29,30)/t17-/m0/s1 RGXBYLCKCQYEHY-KRWDZBQOSA-N 50336692 CHEMBL1672701::N-Butyryl-N-[3-(2-oxotetrahydropyrimidin-1(2H)-yl)propyl]-O-phosphono-L-tyrosinamide Growth factor receptor-bound protein 2 Homo sapiens 314000 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336692&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 51002711 125086794 CHEMBL1672701 C01167 ZINC66098056 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50622872 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCCCN1CCCNC1=O InChI=1S/C18H27N4O7P/c1-13(23)21-16(12-14-4-6-15(7-5-14)29-30(26,27)28)17(24)19-8-2-10-22-11-3-9-20-18(22)25/h4-7,16H,2-3,8-12H2,1H3,(H,19,24)(H,20,25)(H,21,23)(H2,26,27,28)/t16-/m0/s1 RIBDYTODEHUADD-INIZCTEOSA-N 50336693 CHEMBL1672697::N-Acetyl-N-[3-(2-oxotetrahydropyrimidin-1(2H)-yl)propyl]-O-phosphono-L-tyrosinamide Growth factor receptor-bound protein 2 Homo sapiens 174000 ChEMBL 10.1021/jm101478n 10.7270/Q20002CC 21271718 Orcajo-Rincon, L; Ortega-Gutierrez, S; Serrano, P; Torrecillas, IR; Wuthrich, K; Campillo, M; Pardo, L; Viso, A; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336693&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 51002668 125086795 CHEMBL1672697 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50727729 CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1 RJURFGZVJUQBHK-IIXSONLDSA-N 43866 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide::2-amino-4,6-dimethyl-3-oxo-N1,N9-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide::2-amino-N,N''''-bis[(3R,6S,7R,10S,16S)-3,10-diisopropyl-2,5,9,12,15-pentaketo-7,11,14-trimethyl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-3-keto-4,6-dimethyl-phenoxazine-1,9-dicarboxamide::2-amino-N,N''-bis[(3R,6S,7R,10S,16S)-3,10-diisopropyl-2,5,9,12,15-pentaketo-7,11,14-trimethyl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-3-keto-4,6-dimethyl-phenoxazine-1,9-dicarboxamide::2-amino-N,N'-bis[(3R,6S,7R,10S,16S)-3,10-diisopropyl-2,5,9,12,15-pentaketo-7,11,14-trimethyl-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-3-keto-4,6-dimethyl-phenoxazine-1,9-dicarboxamide::2-azanyl-4,6-dimethyl-3-oxidanylidene-N1,N9-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentakis(oxidanylidene)-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide::DACTINOMYCIN::Glycopeptide, 4a::MLS001424196::SMR000469227::cid_457193 Growth factor receptor-bound protein 2 Homo sapiens 5000 ChEMBL 10.1016/s0960-894x(98)00345-x 10.7270/Q29K4BQB 9873474 Nam, JY; Kim, HK; Son, KH; Kim, SU; Kwon, BM; Han, MY; Chung, YJ; Bok, SH Korea Research Institute of Bioscience and Biotechnology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43866&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 457193 172097709 27666 DB00970 C06770 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50727730 CCC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)CC)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O InChI=1S/C64H90N12O16/c1-17-31(7)44-61(86)75-25-19-21-38(75)59(84)71(13)27-40(77)73(15)50(29(3)4)63(88)90-35(11)46(57(82)67-44)69-55(80)37-24-23-33(9)53-48(37)66-49-42(43(65)52(79)34(10)54(49)92-53)56(81)70-47-36(12)91-64(89)51(30(5)6)74(16)41(78)28-72(14)60(85)39-22-20-26-76(39)62(87)45(32(8)18-2)68-58(47)83/h23-24,29-32,35-36,38-39,44-47,50-51H,17-22,25-28,65H2,1-16H3,(H,67,82)(H,68,83)(H,69,80)(H,70,81) XLGPRYUFOGVPMM-UHFFFAOYSA-N 50071190 2-Amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid bis-[(5-sec-butyl-12-isopropyl-9,13,16-trimethyl-4,7,11,14,17-pentaoxo-hexadecahydro-10-oxa-3a,6,13,16-tetraaza-cyclopentacyclohexadecen-8-yl)-amide]::CHEMBL413035 Growth factor receptor-bound protein 2 Homo sapiens 7600 ChEMBL 10.1016/s0960-894x(98)00345-x 10.7270/Q29K4BQB 9873474 Nam, JY; Kim, HK; Son, KH; Kim, SU; Kwon, BM; Han, MY; Chung, YJ; Bok, SH Korea Research Institute of Bioscience and Biotechnology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071190&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 122799 103964979 CHEMBL413035 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50727731 CC[C@H](C)[C@@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O InChI=1S/C63H88N12O16/c1-17-31(8)44-61(86)75-25-19-21-38(75)59(84)71(14)27-40(77)72(15)49(29(4)5)62(87)89-34(11)45(57(82)67-44)68-54(79)36-23-22-32(9)52-47(36)65-48-41(42(64)51(78)33(10)53(48)91-52)55(80)69-46-35(12)90-63(88)50(30(6)7)73(16)39(76)26-70(13)58(83)37-20-18-24-74(37)60(85)43(28(2)3)66-56(46)81/h22-23,28-31,34-35,37-38,43-46,49-50H,17-21,24-27,64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)/t31-,34+,35+,37-,38-,43-,44-,45-,46-,49-,50-/m0/s1 QHPKJAQOHMCSLA-IAEPZHFASA-N 50071191 CHEMBL2373069::actinomycin analogue Growth factor receptor-bound protein 2 Homo sapiens 5900 ChEMBL 10.1016/s0960-894x(98)00345-x 10.7270/Q29K4BQB 9873474 Nam, JY; Kim, HK; Son, KH; Kim, SU; Kwon, BM; Han, MY; Chung, YJ; Bok, SH Korea Research Institute of Bioscience and Biotechnology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071191&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 73351843 103964980 CHEMBL2373069 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50810870 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1ccc2ccccc2c1 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-18-6-7-22-10-13-24-8-2-3-9-26(24)19-22)42-37(54)38(16-4-1-5-17-38)43-32(46)27(41-33(47)36(52)53)20-23-11-14-25(15-12-23)30(34(48)49)35(50)51/h2-3,8-15,19,27-28,30H,1,4-7,16-18,20-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 LAQIGICNBGNGJD-NSOVKSMOSA-N 50111441 CHEMBL288116::[1-[1-(6-Carbamoyl-cyclohex-2-enylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 50 ChEMBL 10.1021/jm010468s 10.7270/Q2CN74ND 11931608 Toogood, PL Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111441&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44286528 104006048 CHEMBL288116 ZINC95542427 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50810879 NC(=O)[C@H]1CCC=C[C@H]1NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1 InChI=1S/C31H40N5O9P/c32-22-8-6-7-21(17-22)19-44-30(40)35-26(18-20-11-13-23(14-12-20)45-46(41,42)43)28(38)36-31(15-4-1-5-16-31)29(39)34-25-10-3-2-9-24(25)27(33)37/h3,6-8,10-14,17,24-26H,1-2,4-5,9,15-16,18-19,32H2,(H2,33,37)(H,34,39)(H,35,40)(H,36,38)(H2,41,42,43)/t24-,25+,26-/m0/s1 YENDXPUMHXTISG-NXCFDTQHSA-N 50078347 CHEMBL307890::[(S)-1-[1-((1R,6S)-6-Carbamoyl-cyclohex-2-enylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 1.6 ChEMBL 10.1021/jm010468s 10.7270/Q2CN74ND 11931608 Toogood, PL Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078347&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 444832 103970939 CHEMBL307890 C01167 ZINC26403548 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877437 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O13S/c1-24(2)19-28-39(61)49-29(20-25-12-14-26(52)15-13-25)40(62)51-42(16-5-3-6-17-42)41(63)50-30(21-32(43)53)37(59)45-18-7-4-10-33(54)47-31(36(44)58)22-65(64)23-34(55)46-27(38(60)48-28)9-8-11-35(56)57/h12-15,24,27-31,52H,3-11,16-23H2,1-2H3,(H2,43,53)(H2,44,58)(H,45,59)(H,46,55)(H,47,54)(H,48,60)(H,49,61)(H,50,63)(H,51,62)(H,56,57)/t27-,28-,29-,30-,31-,65-/m0/s1 YNWUNFGKJHUKJS-MWNZNSOUSA-N 50377971 CHEMBL1627243 Growth factor receptor-bound protein 2 Homo sapiens 77000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377971&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 11658039 160857054 CHEMBL1627243 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877438 CC(C)C[C@H](NC(=O)[C@](C)(CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C48H62N8O11/c1-27(2)22-36(54-44(64)47(3,19-11-16-40(59)60)56-46(66)67-26-33-31-14-7-5-12-29(31)30-13-6-8-15-32(30)33)42(62)52-37(24-28-17-18-38(57)34(49)23-28)43(63)55-48(20-9-4-10-21-48)45(65)53-35(41(51)61)25-39(50)58/h5-8,12-15,17-18,23,27,33,35-37,57H,4,9-11,16,19-22,24-26,49H2,1-3H3,(H2,50,58)(H2,51,61)(H,52,62)(H,53,65)(H,54,64)(H,55,63)(H,56,66)(H,59,60)/t35-,36-,37-,47-/m0/s1 YHRZCHZWBKUSSM-NBINMNPFSA-N 50264470 CHEMBL500357::N-Fmoc-(S)-(alpha-Me)Adi-Leu-(3'-NH2-Tyr)-Ac6c-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 3900 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264470&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25131526 104112477 CHEMBL500357 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877439 CC(C)C[C@H](NC(=O)[C@@](C)(CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C48H62N8O11/c1-27(2)22-36(54-44(64)47(3,19-11-16-40(59)60)56-46(66)67-26-33-31-14-7-5-12-29(31)30-13-6-8-15-32(30)33)42(62)52-37(24-28-17-18-38(57)34(49)23-28)43(63)55-48(20-9-4-10-21-48)45(65)53-35(41(51)61)25-39(50)58/h5-8,12-15,17-18,23,27,33,35-37,57H,4,9-11,16,19-22,24-26,49H2,1-3H3,(H2,50,58)(H2,51,61)(H,52,62)(H,53,65)(H,54,64)(H,55,63)(H,56,66)(H,59,60)/t35-,36-,37-,47+/m0/s1 YHRZCHZWBKUSSM-XZKLWLDRSA-N 50264469 CHEMBL499251::N-Fmoc-(R)-(alpha-Me)Adi-Leu-(3'-NH2-Tyr)-Ac6c-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 700000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264469&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25130200 104112476 CHEMBL499251 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877440 CC(C)C[C@H](NC(=O)[C@](C)(CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C48H61N7O11/c1-28(2)24-37(53-44(63)47(3,21-11-16-40(58)59)55-46(65)66-27-35-33-14-7-5-12-31(33)32-13-6-8-15-34(32)35)42(61)51-38(25-29-17-19-30(56)20-18-29)43(62)54-48(22-9-4-10-23-48)45(64)52-36(41(50)60)26-39(49)57/h5-8,12-15,17-20,28,35-38,56H,4,9-11,16,21-27H2,1-3H3,(H2,49,57)(H2,50,60)(H,51,61)(H,52,64)(H,53,63)(H,54,62)(H,55,65)(H,58,59)/t36-,37-,38-,47-/m0/s1 FASHBEYWMWPUMG-XCJGHBKGSA-N 50264468 CHEMBL461032::N-Fmoc-(S)-(alpha-Me)Adi-Leu-Tyr-Ac6c-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 117700 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264468&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25131877 104112475 CHEMBL461032 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877441 CC(C)C[C@H](NC(=O)[C@@](C)(CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C48H61N7O11/c1-28(2)24-37(53-44(63)47(3,21-11-16-40(58)59)55-46(65)66-27-35-33-14-7-5-12-31(33)32-13-6-8-15-34(32)35)42(61)51-38(25-29-17-19-30(56)20-18-29)43(62)54-48(22-9-4-10-23-48)45(64)52-36(41(50)60)26-39(49)57/h5-8,12-15,17-20,28,35-38,56H,4,9-11,16,21-27H2,1-3H3,(H2,49,57)(H2,50,60)(H,51,61)(H,52,64)(H,53,63)(H,54,62)(H,55,65)(H,58,59)/t36-,37-,38-,47+/m0/s1 FASHBEYWMWPUMG-DMMFMOCHSA-N 50264467 CHEMBL448312::N-Fmoc-(R)-(alpha-Me)Adi-Leu-Tyr-Ac6c-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens >1000000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264467&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25130199 104112474 CHEMBL448312 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877442 CC(C)C[C@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C47H58N8O13/c1-24(2)18-34(51-41(60)36(21-30(43(62)63)44(64)65)54-46(67)68-23-31-28-12-6-4-10-26(28)27-11-5-7-13-29(27)31)40(59)52-35(20-25-14-15-37(56)32(48)19-25)42(61)55-47(16-8-3-9-17-47)45(66)53-33(39(50)58)22-38(49)57/h4-7,10-15,19,24,30-31,33-36,56H,3,8-9,16-18,20-23,48H2,1-2H3,(H2,49,57)(H2,50,58)(H,51,60)(H,52,59)(H,53,66)(H,54,67)(H,55,61)(H,62,63)(H,64,65)/t33-,34-,35-,36-/m0/s1 NHODJGBYZJPOMD-ZYADHFCISA-N 50264466 CHEMBL444948::N-Fmoc-Gla-Leu-(3'-NH2-Tyr)-Ac6c-Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 2500 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264466&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25131201 104112473 CHEMBL444948 C06246 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877443 CC(C)C[C@H](NC(=O)[C@H](CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C47H60N8O11/c1-26(2)21-36(51-42(61)34(15-10-16-40(58)59)54-46(65)66-25-32-30-13-6-4-11-28(30)29-12-5-7-14-31(29)32)43(62)52-37(23-27-17-18-38(56)33(48)22-27)44(63)55-47(19-8-3-9-20-47)45(64)53-35(41(50)60)24-39(49)57/h4-7,11-14,17-18,22,26,32,34-37,56H,3,8-10,15-16,19-21,23-25,48H2,1-2H3,(H2,49,57)(H2,50,60)(H,51,61)(H,52,62)(H,53,64)(H,54,65)(H,55,63)(H,58,59)/t34-,35-,36-,37-/m0/s1 PIVVHTMTNRIPFL-BQYLNSIHSA-N 50264465 CHEMBL462230::N-Fmoc-Adi-Leu-(3'-NH2-Tyr)-Ac6c-Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 5800 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264465&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25129840 104112472 CHEMBL462230 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877444 C[C@@](CCC(O)=O)(NC(=O)[C@H](Cc1ccc(O)c(CCC(O)=O)c1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C37H41N5O11/c1-37(15-14-32(47)48,35(51)40-27(33(39)49)18-30(38)44)42-34(50)28(17-20-10-12-29(43)21(16-20)11-13-31(45)46)41-36(52)53-19-26-24-8-4-2-6-22(24)23-7-3-5-9-25(23)26/h2-10,12,16,26-28,43H,11,13-15,17-19H2,1H3,(H2,38,44)(H2,39,49)(H,40,51)(H,41,52)(H,42,50)(H,45,46)(H,47,48)/t27-,28-,37-/m0/s1 IZZWRPOZUDLZPO-FPQSRERTSA-N 50264464 CHEMBL448041::N-Fmoc-(3'-CH2CH2CO2H-Tyr)-(alpha-Me)Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 168000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264464&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25129839 104112471 CHEMBL448041 ZINC49833563 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877445 C[C@@](CCC(O)=O)(NC(=O)[C@@H](N)Cc1ccc(O)c(CCO)c1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C21H31N5O8/c1-21(6-4-17(30)31,20(34)25-14(18(24)32)10-16(23)29)26-19(33)13(22)9-11-2-3-15(28)12(8-11)5-7-27/h2-3,8,13-14,27-28H,4-7,9-10,22H2,1H3,(H2,23,29)(H2,24,32)(H,25,34)(H,26,33)(H,30,31)/t13-,14-,21-/m0/s1 TYASIGUZBCAEEQ-RXSFTSLZSA-N 50264463 CHEMBL489405::H-(3'-CH2CH2CO2H-Tyr)-(alpha-Me)Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 290000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264463&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44579868 104112470 CHEMBL489405 ZINC45496021 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877446 CC(C)C[C@H](NC(=O)[C@H](CCCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(CCC(O)=O)c1)C(=O)N[C@@](C)(CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C49H61N7O15/c1-26(2)21-36(52-44(66)34(13-8-14-40(59)60)55-48(70)71-25-33-31-11-6-4-9-29(31)30-10-5-7-12-32(30)33)45(67)53-37(23-27-15-17-38(57)28(22-27)16-18-41(61)62)46(68)56-49(3,20-19-42(63)64)47(69)54-35(43(51)65)24-39(50)58/h4-7,9-12,15,17,22,26,33-37,57H,8,13-14,16,18-21,23-25H2,1-3H3,(H2,50,58)(H2,51,65)(H,52,66)(H,53,67)(H,54,69)(H,55,70)(H,56,68)(H,59,60)(H,61,62)(H,63,64)/t34-,35-,36-,37-,49-/m0/s1 NDTISLMXNHNWFZ-ZLICEJRNSA-N 50264462 CHEMBL445342::N-Fmoc-Adi-Leu-(3'-CH2CH2CO2H-Tyr)-Ac6c-Glu-Asnamide Growth factor receptor-bound protein 2 Homo sapiens 5600 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264462&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25129838 104112469 CHEMBL445342 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877447 CC(C)C[C@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)N[C@@](C)(CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C46H56N8O15/c1-22(2)16-32(50-40(61)34(19-28(42(63)64)43(65)66)53-45(68)69-21-29-26-10-6-4-8-24(26)25-9-5-7-11-27(25)29)39(60)51-33(18-23-12-13-35(55)30(47)17-23)41(62)54-46(3,15-14-37(57)58)44(67)52-31(38(49)59)20-36(48)56/h4-13,17,22,28-29,31-34,55H,14-16,18-21,47H2,1-3H3,(H2,48,56)(H2,49,59)(H,50,61)(H,51,60)(H,52,67)(H,53,68)(H,54,62)(H,57,58)(H,63,64)(H,65,66)/t31-,32-,33-,34-,46-/m0/s1 NTWIIPXPRFWSTH-YZVZLXLVSA-N 50264461 CHEMBL508925::N-Fmoc-Gla-Leu-(3'-NH2-Tyr)-(alpha-Me)Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 4400 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264461&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25131199 104112468 CHEMBL508925 C06246 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877448 CC(C)C[C@H](NC(=O)[C@@H](N)CC(C(O)=O)C(O)=O)C(=O)N[C@@H](Cc1ccc(O)c(N)c1)C(=O)N[C@@](C)(CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C31H46N8O13/c1-13(2)8-19(36-25(45)17(33)11-15(28(48)49)29(50)51)26(46)37-20(10-14-4-5-21(40)16(32)9-14)27(47)39-31(3,7-6-23(42)43)30(52)38-18(24(35)44)12-22(34)41/h4-5,9,13,15,17-20,40H,6-8,10-12,32-33H2,1-3H3,(H2,34,41)(H2,35,44)(H,36,45)(H,37,46)(H,38,52)(H,39,47)(H,42,43)(H,48,49)(H,50,51)/t17-,18-,19-,20-,31-/m0/s1 ZZEDSXVXZQRBIG-BFIFYPHRSA-N 50264460 CHEMBL507364::H-Gla-Leu-(3'-NH2-Tyr)-(alpha-Me)Glu-Asn-amide Growth factor receptor-bound protein 2 Homo sapiens 19000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264460&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25130198 104112467 CHEMBL507364 ZINC49898831 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877449 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H62N10O17S/c1-20(2)13-24-36(61)50-25(15-21-9-10-29(53)23(43)14-21)38(63)52-42(3,11-6-8-33(57)58)41(68)51-27(17-30(44)54)35(60)46-12-5-4-7-31(55)48-28(34(45)59)18-70(69)19-32(56)47-26(37(62)49-24)16-22(39(64)65)40(66)67/h9-10,14,20,22,24-28,53H,4-8,11-13,15-19,43H2,1-3H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,62)(H,50,61)(H,51,68)(H,52,63)(H,57,58)(H,64,65)(H,66,67)/t24-,25-,26-,27-,28-,42-,70-/m0/s1 ABDOMXLUKVBAHG-SRTBCYECSA-N 50377972 CHEMBL1627266 Growth factor receptor-bound protein 2 Homo sapiens 1150 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377972&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53324542 160857055 CHEMBL1627266 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877450 CC(C)C[C@@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C42H62N10O16S/c1-20(2)13-24-36(61)50-25(15-21-9-10-29(53)23(43)14-21)38(63)52-42(3,11-6-8-33(57)58)41(68)51-27(17-30(44)54)35(60)46-12-5-4-7-31(55)48-28(34(45)59)18-69-19-32(56)47-26(37(62)49-24)16-22(39(64)65)40(66)67/h9-10,14,20,22,24-28,53H,4-8,11-13,15-19,43H2,1-3H3,(H2,44,54)(H2,45,59)(H,46,60)(H,47,56)(H,48,55)(H,49,62)(H,50,61)(H,51,68)(H,52,63)(H,57,58)(H,64,65)(H,66,67)/t24-,25-,26-,27-,28-,42-/m0/s1 IVVFLCYFHQUBJM-UFWUBRIUSA-N 50264458 CHEMBL452659::Cyclo-[CH2-CO-Gla-Leu-(3'-NH2-Tyr)-(alpha-Me)Adi-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 9500 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264458&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25129139 104112465 CHEMBL452659 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877451 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C41H62N10O15S/c1-21(2)15-25-38(63)49-26(17-22-10-11-29(52)23(42)16-22)39(64)51-41(3,13-12-34(58)59)40(65)50-27(18-30(43)53)36(61)45-14-5-4-8-31(54)47-28(35(44)60)19-67(66)20-32(55)46-24(37(62)48-25)7-6-9-33(56)57/h10-11,16,21,24-28,52H,4-9,12-15,17-20,42H2,1-3H3,(H2,43,53)(H2,44,60)(H,45,61)(H,46,55)(H,47,54)(H,48,62)(H,49,63)(H,50,65)(H,51,64)(H,56,57)(H,58,59)/t24-,25-,26-,27-,28-,41-,67-/m0/s1 XVYSZASHMVMGOQ-YOIQKKBLSA-N 50377973 CHEMBL1627272 Growth factor receptor-bound protein 2 Homo sapiens 8100 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377973&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321818 160857056 CHEMBL1627272 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877452 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)c(N)c2)NC1=O)C(N)=O InChI=1S/C41H62N10O14S/c1-21(2)15-25-38(63)49-26(17-22-10-11-29(52)23(42)16-22)39(64)51-41(3,13-12-34(58)59)40(65)50-27(18-30(43)53)36(61)45-14-5-4-8-31(54)47-28(35(44)60)19-66-20-32(55)46-24(37(62)48-25)7-6-9-33(56)57/h10-11,16,21,24-28,52H,4-9,12-15,17-20,42H2,1-3H3,(H2,43,53)(H2,44,60)(H,45,61)(H,46,55)(H,47,54)(H,48,62)(H,49,63)(H,50,65)(H,51,64)(H,56,57)(H,58,59)/t24-,25-,26-,27-,28-,41-/m0/s1 UPDYXBNIGCRVRH-SCLMUVDBSA-N 50264456 CHEMBL502730::Cyclo-[CH2-CO-Adi-Leu-(3'-NH2-Tyr)-(alpha-Me)Glu-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 17000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264456&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25128784 104112463 CHEMBL502730 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877453 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C41H61N9O15S/c1-22(2)17-26-38(62)48-27(18-23-10-12-24(51)13-11-23)39(63)50-41(3,15-14-34(57)58)40(64)49-28(19-30(42)52)36(60)44-16-5-4-8-31(53)46-29(35(43)59)20-66(65)21-32(54)45-25(37(61)47-26)7-6-9-33(55)56/h10-13,22,25-29,51H,4-9,14-21H2,1-3H3,(H2,42,52)(H2,43,59)(H,44,60)(H,45,54)(H,46,53)(H,47,61)(H,48,62)(H,49,64)(H,50,63)(H,55,56)(H,57,58)/t25-,26-,27-,28-,29-,41+,66-/m0/s1 UCCGLCNSBNUACW-DBPLSCOBSA-N 50377974 CHEMBL1627271 Growth factor receptor-bound protein 2 Homo sapiens 30500 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377974&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53320556 160857057 CHEMBL1627271 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877454 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C41H61N9O14S/c1-22(2)17-26-38(62)48-27(18-23-10-12-24(51)13-11-23)39(63)50-41(3,15-14-34(57)58)40(64)49-28(19-30(42)52)36(60)44-16-5-4-8-31(53)46-29(35(43)59)20-65-21-32(54)45-25(37(61)47-26)7-6-9-33(55)56/h10-13,22,25-29,51H,4-9,14-21H2,1-3H3,(H2,42,52)(H2,43,59)(H,44,60)(H,45,54)(H,46,53)(H,47,61)(H,48,62)(H,49,64)(H,50,63)(H,55,56)(H,57,58)/t25-,26-,27-,28-,29-,41+/m0/s1 WVKCHDVKWXSAMH-JRLFFDIGSA-N 50264454 CHEMBL450367::Cyclo-[CH2-CO-Adi-Leu-Tyr-(D-(alpha-Me)Glu)-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 60500 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264454&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25128783 104112461 CHEMBL450367 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877455 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O15S/c1-23(2)18-27-39(63)49-28(19-24-12-14-25(52)15-13-24)40(64)51-42(3,16-7-11-35(58)59)41(65)50-29(20-31(43)53)37(61)45-17-5-4-9-32(54)47-30(36(44)60)21-67(66)22-33(55)46-26(38(62)48-27)8-6-10-34(56)57/h12-15,23,26-30,52H,4-11,16-22H2,1-3H3,(H2,43,53)(H2,44,60)(H,45,61)(H,46,55)(H,47,54)(H,48,62)(H,49,63)(H,50,65)(H,51,64)(H,56,57)(H,58,59)/t26-,27-,28-,29-,30-,42-,67-/m0/s1 AVHNCXVOPVMXDV-BFASKPKPSA-N 50377975 CHEMBL1627245 Growth factor receptor-bound protein 2 Homo sapiens 17000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377975&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53324568 160857058 CHEMBL1627245 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877456 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C42H63N9O14S/c1-23(2)18-27-39(63)49-28(19-24-12-14-25(52)15-13-24)40(64)51-42(3,16-7-11-35(58)59)41(65)50-29(20-31(43)53)37(61)45-17-5-4-9-32(54)47-30(36(44)60)21-66-22-33(55)46-26(38(62)48-27)8-6-10-34(56)57/h12-15,23,26-30,52H,4-11,16-22H2,1-3H3,(H2,43,53)(H2,44,60)(H,45,61)(H,46,55)(H,47,54)(H,48,62)(H,49,63)(H,50,65)(H,51,64)(H,56,57)(H,58,59)/t26-,27-,28-,29-,30-,42-/m0/s1 MFSVYGGMRQNUNU-KWAGMYHTSA-N 50264452 CHEMBL455745::Cyclo-[CH2-CO-Adi-Leu-Tyr-(alpha-Me)Adi-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 60700 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264452&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25128782 104112459 CHEMBL455745 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877457 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C41H61N9O15S/c1-22(2)17-26-38(62)48-27(18-23-10-12-24(51)13-11-23)39(63)50-41(3,15-14-34(57)58)40(64)49-28(19-30(42)52)36(60)44-16-5-4-8-31(53)46-29(35(43)59)20-66(65)21-32(54)45-25(37(61)47-26)7-6-9-33(55)56/h10-13,22,25-29,51H,4-9,14-21H2,1-3H3,(H2,42,52)(H2,43,59)(H,44,60)(H,45,54)(H,46,53)(H,47,61)(H,48,62)(H,49,64)(H,50,63)(H,55,56)(H,57,58)/t25-,26-,27-,28-,29-,41-,66-/m0/s1 UCCGLCNSBNUACW-HPYJIRDQSA-N 50377976 CHEMBL1627242 Growth factor receptor-bound protein 2 Homo sapiens 18000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377976&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321882 160857059 CHEMBL1627242 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877458 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C41H61N9O14S/c1-22(2)17-26-38(62)48-27(18-23-10-12-24(51)13-11-23)39(63)50-41(3,15-14-34(57)58)40(64)49-28(19-30(42)52)36(60)44-16-5-4-8-31(53)46-29(35(43)59)20-65-21-32(54)45-25(37(61)47-26)7-6-9-33(55)56/h10-13,22,25-29,51H,4-9,14-21H2,1-3H3,(H2,42,52)(H2,43,59)(H,44,60)(H,45,54)(H,46,53)(H,47,61)(H,48,62)(H,49,64)(H,50,63)(H,55,56)(H,57,58)/t25-,26-,27-,28-,29-,41-/m0/s1 WVKCHDVKWXSAMH-QIMBRPPISA-N 50264450 CHEMBL501412::Cyclo-[CH2-CO-Adi-Leu-Tyr-(alpha-Me)Glu-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 70000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264450&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25129138 104112457 CHEMBL501412 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877459 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)C[S@@](=O)C[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C40H59N9O15S/c1-21(2)15-25-37(61)47-26(16-22-10-12-23(50)13-11-22)38(62)49-40(3,18-33(56)57)39(63)48-27(17-29(41)51)35(59)43-14-5-4-8-30(52)45-28(34(42)58)19-65(64)20-31(53)44-24(36(60)46-25)7-6-9-32(54)55/h10-13,21,24-28,50H,4-9,14-20H2,1-3H3,(H2,41,51)(H2,42,58)(H,43,59)(H,44,53)(H,45,52)(H,46,60)(H,47,61)(H,48,63)(H,49,62)(H,54,55)(H,56,57)/t24-,25-,26-,27-,28-,40-,65-/m0/s1 LWUIHCMGSIIGLF-LSBQOWSOSA-N 50377977 CHEMBL1627260 Growth factor receptor-bound protein 2 Homo sapiens 30500 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50377977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50377977&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53317891 160857060 CHEMBL1627260 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50877460 CC(C)C[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)CSC[C@H](NC(=O)CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@](C)(CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C40H59N9O14S/c1-21(2)15-25-37(61)47-26(16-22-10-12-23(50)13-11-22)38(62)49-40(3,18-33(56)57)39(63)48-27(17-29(41)51)35(59)43-14-5-4-8-30(52)45-28(34(42)58)19-64-20-31(53)44-24(36(60)46-25)7-6-9-32(54)55/h10-13,21,24-28,50H,4-9,14-20H2,1-3H3,(H2,41,51)(H2,42,58)(H,43,59)(H,44,53)(H,45,52)(H,46,60)(H,47,61)(H,48,63)(H,49,62)(H,54,55)(H,56,57)/t24-,25-,26-,27-,28-,40-/m0/s1 FWBCTGIRNCZLQT-OZACWGMRSA-N 50264448 CHEMBL501397::Cyclo-[CH2-CO-Adi-Leu-Tyr-(alpha-Me)Asp-Asn-Ava-Cys]-amide Growth factor receptor-bound protein 2 Homo sapiens 108000 ChEMBL 10.1021/jm800487r 10.7270/Q2XG9S2N 18821748 Long, YQ; Xue, T; Song, YL; Liu, ZL; Huang, SX; Yu, Q Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264448&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 25133937 104112455 CHEMBL501397 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883704 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCNC1=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C30H46N7O10P/c1-17(2)23-27(41)33-15-7-4-8-20(31)25(39)36-24(18-9-11-19(12-10-18)47-48(44,45)46)28(42)37-30(13-5-3-6-14-30)29(43)34-21(16-22(32)38)26(40)35-23/h9-12,17,20-21,23-24H,3-8,13-16,31H2,1-2H3,(H2,32,38)(H,33,41)(H,34,43)(H,35,40)(H,36,39)(H,37,42)(H2,44,45,46)/t20-,21-,23-,24-/m0/s1 SZFCMVWIDWVDNT-WMIMKTLMSA-N 50294420 4-[(9S,12S,19S,22S)-12-amino-22-(carbamoylmethyl)-8,11,18,21,24-pentaoxo-19-(propan-2-yl)-7,10,17,20,23-pentaazaspiro[5.18]tetracosan-9-yl]phenoxyphosphonic acid::CHEMBL538142 Growth factor receptor-bound protein 2 Homo sapiens 7550 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294420&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45268910 104135951 CHEMBL538142 ZINC96307590 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883705 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCNC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O InChI=1S/C29H43N8O11PS/c1-15(2)23-27(43)34-20(24(31)40)12-50-13-22(39)33-18(10-16-4-6-17(7-5-16)48-49(45,46)47)26(42)37-29(8-3-9-32-14-29)28(44)35-19(11-21(30)38)25(41)36-23/h4-7,15,18-20,23,32H,3,8-14H2,1-2H3,(H2,30,38)(H2,31,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47)/t18-,19-,20-,23-,29?/m0/s1 HIOLSTZWHFWABX-LZIFKYDKSA-N 50294421 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-8,11,17,20,23-pentaoxo-18-(propan-2-yl)-13-thia-2,7,10,16,19,22-hexaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL539207 Growth factor receptor-bound protein 2 Homo sapiens 359 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294421&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44187551 104135952 CHEMBL539207 ZINC96307592 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883706 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCS(=O)(=O)CC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O InChI=1S/C29H42N7O13PS2/c1-15(2)23-27(42)33-20(24(31)39)13-51-14-22(38)32-18(11-16-3-5-17(6-4-16)49-50(44,45)46)26(41)36-29(7-9-52(47,48)10-8-29)28(43)34-19(12-21(30)37)25(40)35-23/h3-6,15,18-20,23H,7-14H2,1-2H3,(H2,30,37)(H2,31,39)(H,32,38)(H,33,42)(H,34,43)(H,35,40)(H,36,41)(H2,44,45,46)/t18-,19-,20-,23-/m0/s1 WNMRJFLYOXPWEZ-MXBUBSDBSA-N 50294422 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-3,3,8,11,17,20,23-heptaoxo-18-(propan-2-yl)-3,13-dithia-7,10,16,19,22-pentaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL552951 Growth factor receptor-bound protein 2 Homo sapiens 880 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294422&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45268029 104135953 CHEMBL552951 ZINC96307593 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883707 NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc3ccccc3c2)NC1=O)C(N)=O InChI=1S/C38H46N7O12PS/c39-31(46)19-29-35(50)42-27(18-23-8-11-24-6-2-3-7-25(24)16-23)34(49)43-30(33(40)48)20-59(56)21-32(47)41-28(17-22-9-12-26(13-10-22)57-58(53,54)55)36(51)45-38(37(52)44-29)14-4-1-5-15-38/h2-3,6-13,16,27-30H,1,4-5,14-15,17-21H2,(H2,39,46)(H2,40,48)(H,41,47)(H,42,50)(H,43,49)(H,44,52)(H,45,51)(H2,53,54,55) DAQPYJWTQOPFTE-UHFFFAOYSA-N 50378056 CHEMBL1627249 Growth factor receptor-bound protein 2 Homo sapiens 4800 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378056&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53319194 160857139 CHEMBL1627249 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883708 NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O)C(N)=O InChI=1S/C36H45N8O12PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-58(55)19-30(46)40-25(14-20-8-10-22(11-9-20)56-57(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54) KTTGKKNCOFLFGY-UHFFFAOYSA-N 50378057 CHEMBL1627267 Growth factor receptor-bound protein 2 Homo sapiens 1290 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378057&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321862 160857140 CHEMBL1627267 ZINC96203243 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883709 NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O)C(N)=O InChI=1S/C36H45N8O12PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-58(55)19-30(46)40-25(14-20-8-10-22(11-9-20)56-57(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54) KTTGKKNCOFLFGY-UHFFFAOYSA-N 50378057 CHEMBL1627267 Growth factor receptor-bound protein 2 Homo sapiens 2140 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378057&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321862 160857140 CHEMBL1627267 ZINC96203243 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883710 NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C34H44N7O13PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-56(53)18-28(44)37-24(15-20-6-10-22(11-7-20)54-55(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52) DKTMPOVPYUHWJS-UHFFFAOYSA-N 50378058 CHEMBL1627247 Growth factor receptor-bound protein 2 Homo sapiens 1720 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378058&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53317943 160857141 CHEMBL1627247 ZINC96203246 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883711 NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C34H44N7O13PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-56(53)18-28(44)37-24(15-20-6-10-22(11-7-20)54-55(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52) DKTMPOVPYUHWJS-UHFFFAOYSA-N 50378058 CHEMBL1627247 Growth factor receptor-bound protein 2 Homo sapiens 1360 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378058&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53317943 160857141 CHEMBL1627247 ZINC96203246 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883712 CC(C)C1NC(=O)C(CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC1=O)C(N)=O InChI=1S/C30H44N7O12PS/c1-16(2)24-28(43)34-21(25(32)40)14-51(48)15-23(39)33-19(12-17-6-8-18(9-7-17)49-50(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47) YMVUJHXTYPJWIN-UHFFFAOYSA-N 50378059 CHEMBL1627251 Growth factor receptor-bound protein 2 Homo sapiens 1760 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378059&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321070 160857142 CHEMBL1627251 ZINC96203249 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883713 CC(C)C1NC(=O)C(CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC1=O)C(N)=O InChI=1S/C30H44N7O12PS/c1-16(2)24-28(43)34-21(25(32)40)14-51(48)15-23(39)33-19(12-17-6-8-18(9-7-17)49-50(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47) YMVUJHXTYPJWIN-UHFFFAOYSA-N 50378059 CHEMBL1627251 Growth factor receptor-bound protein 2 Homo sapiens 1560 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378059&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 53321070 160857142 CHEMBL1627251 ZINC96203249 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883714 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O)C(N)=O InChI=1S/C38H46N7O11PS/c39-31(46)19-29-35(50)42-27(18-23-8-11-24-6-2-3-7-25(24)16-23)34(49)43-30(33(40)48)20-58-21-32(47)41-28(17-22-9-12-26(13-10-22)56-57(53,54)55)36(51)45-38(37(52)44-29)14-4-1-5-15-38/h2-3,6-13,16,27-30H,1,4-5,14-15,17-21H2,(H2,39,46)(H2,40,48)(H,41,47)(H,42,50)(H,43,49)(H,44,52)(H,45,51)(H2,53,54,55)/t27-,28-,29-,30-/m0/s1 SZRYMMKXTGVKTD-KRCBVYEFSA-N 50294415 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-18-(naphthalen-2-ylmethyl)-8,11,17,20,23-pentaoxo-13-thia-7,10,16,19,22-pentaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL555424 Growth factor receptor-bound protein 2 Homo sapiens 2710 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294415&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45268908 104135946 CHEMBL555424 ZINC96307585 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883715 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O InChI=1S/C36H45N8O11PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-57-19-30(46)40-25(14-20-8-10-22(11-9-20)55-56(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54)/t25-,26-,27-,28-/m0/s1 TYGHMNBMLZMNPC-LJWNLINESA-N 50294416 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-18-(1H-indol-3-ylmethyl)-8,11,17,20,23-pentaoxo-13-thia-7,10,16,19,22-pentaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL555431 Growth factor receptor-bound protein 2 Homo sapiens 1050 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294416&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45267174 104135947 CHEMBL555431 ZINC96307586 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883716 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O InChI=1S/C34H44N7O12PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-55-18-28(44)37-24(15-20-6-10-22(11-7-20)53-54(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52)/t23-,24-,25-,26-/m0/s1 WUGDAJPNWXMGLH-CQJMVLFOSA-N 50294417 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-18-[(4-hydroxyphenyl)methyl]-8,11,17,20,23-pentaoxo-13-thia-7,10,16,19,22-pentaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL554994 Growth factor receptor-bound protein 2 Homo sapiens 1060 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294417&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45272294 104135948 CHEMBL554994 ZINC96307587 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883717 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O InChI=1S/C30H44N7O11PS/c1-16(2)24-28(43)34-21(25(32)40)14-50-15-23(39)33-19(12-17-6-8-18(9-7-17)48-49(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47)/t19-,20-,21-,24-/m0/s1 XNJGRGUYRZTSMC-CIEVZJJWSA-N 50294418 4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmethyl)-8,11,17,20,23-pentaoxo-18-(propan-2-yl)-13-thia-7,10,16,19,22-pentaazaspiro[5.17]tricosan-9-yl]methyl}phenoxyphosphonic acid::CHEMBL558991 Growth factor receptor-bound protein 2 Homo sapiens 1420 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294418&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45269755 104135949 CHEMBL558991 ZINC96307588 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883718 CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O InChI=1S/C28H40N7O13PS/c1-13(2)23-28(44)34-19(24(30)40)11-50-12-21(37)31-17(9-14-3-5-15(6-4-14)48-49(45,46)47)26(42)32-16(7-8-22(38)39)25(41)33-18(10-20(29)36)27(43)35-23/h3-6,13,16-19,23H,7-12H2,1-2H3,(H2,29,36)(H2,30,40)(H,31,37)(H,32,42)(H,33,41)(H,34,44)(H,35,43)(H,38,39)(H2,45,46,47)/t16-,17-,18-,19-,23-/m0/s1 IUNYROASPFJIRI-QUVRYOLLSA-N 50294419 3-[(5S,8S,11S,14S,17R)-17-carbamoyl-11-(carbamoylmethyl)-3,6,9,12,15-pentaoxo-5-{[4-(phosphonooxy)phenyl]methyl}-14-(propan-2-yl)-1-thia-4,7,10,13,16-pentaazacyclooctadecan-8-yl]propanoic acid::CHEMBL539206 Growth factor receptor-bound protein 2 Homo sapiens 3600 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294419&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 45272293 104135950 CHEMBL539206 ZINC96307589 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883719 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 BZLRZJFFHMIABH-AGEHIQCHSA-N 50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide Growth factor receptor-bound protein 2 Homo sapiens 25000 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124303&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383302 104016640 CHEMBL444114 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50883720 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 BZLRZJFFHMIABH-AGEHIQCHSA-N 50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide Growth factor receptor-bound protein 2 Homo sapiens 15000 ChEMBL 10.1016/j.bmcl.2009.03.134 10.7270/Q2862HC2 19362470 Jiang, S; Liao, C; Bindu, L; Yin, B; Worthy, KW; Fisher, RJ; Burke, TR; Nicklaus, MC; Roller, PP Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124303&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383302 104016640 CHEMBL444114 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50977338 Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1 WYANCIQWFFQARP-AZSCFGFUSA-N 50139762 CHEMBL349373::[(16R,20S)-18-((S)-Carbamoylmethyl)-14-(5-methyl-indol-1-ylmethyl)-20-(S)-oxo-8,17-dioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(R)-18-Carbamoylmethyl-14-(5-methyl-indol-1-ylmethyl)-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 630 ChEMBL 10.1021/jm1012374 10.7270/Q28C9XDV 21381769 Marsault, E; Peterson, ML Universite£ de Sherbrooke http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139762&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 24994240 104029591 CHEMBL349373 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51067938 CC1(C)N=C(N)N=C(N)N1c1cccc(\C=C\C=Cc2cccc(c2)[N+]([O-])=O)c1 InChI=1S/C21H22N6O2/c1-21(2)25-19(22)24-20(23)26(21)17-11-5-9-15(13-17)7-3-4-8-16-10-6-12-18(14-16)27(28)29/h3-14H,1-2H3,(H4,22,23,24,25)/b7-3+,8-4? ZZVOXTZBGFEGTL-OJQZMLLLSA-N 50436051 CHEMBL2396935 Growth factor receptor-bound protein 2 Homo sapiens 320000 ChEMBL 10.1016/j.bmc.2012.10.023 10.7270/Q2M32X4Z 23182216 Simister, PC; Luccarelli, J; Thompson, S; Appella, DH; Feller, SM; Hamilton, AD University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436051&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5474940 175448368 CHEMBL2396935 ZINC17020573 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51067939 CC1(C)N=C(N)N=C(N)N1c1cccc(CCCCc2cccc(N)c2)c1 InChI=1S/C21H28N6/c1-21(2)26-19(23)25-20(24)27(21)18-12-6-10-16(14-18)8-4-3-7-15-9-5-11-17(22)13-15/h5-6,9-14H,3-4,7-8,22H2,1-2H3,(H4,23,24,25,26) WNZMAGKIGDUEIH-UHFFFAOYSA-N 50436052 CHEMBL2396934 Growth factor receptor-bound protein 2 Homo sapiens 5700000 ChEMBL 10.1016/j.bmc.2012.10.023 10.7270/Q2M32X4Z 23182216 Simister, PC; Luccarelli, J; Thompson, S; Appella, DH; Feller, SM; Hamilton, AD University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50436052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50436052&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 419052 175448369 CHEMBL2396934 ZINC01701932 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50020396 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C1CCCCC1)C(N)=O InChI=1S/C61H86N12O19S/c1-31(2)23-39-51(80)67-41(25-34-15-19-37(75)20-16-34)55(84)73-61(21-9-6-10-22-61)60(91)70-43(27-45(62)76)54(83)72-48(32(3)4)56(85)64-28-46(77)71-49(35-11-7-5-8-12-35)57(86)68-40(24-33-13-17-36(74)18-14-33)52(81)69-44(50(63)79)29-93(92)30-47(78)65-42(53(82)66-39)26-38(58(87)88)59(89)90/h13-20,31-32,35,38-44,48-49,74-75H,5-12,21-30H2,1-4H3,(H2,62,76)(H2,63,79)(H,64,85)(H,65,78)(H,66,82)(H,67,80)(H,68,86)(H,69,81)(H,70,91)(H,71,77)(H,72,83)(H,73,84)(H,87,88)(H,89,90)/t39-,40+,41+,42+,43+,44+,48-,49-,93?/m1/s1 PQOPKORIBIGSBW-QVNPOUQNSA-N 50129420 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Cha Tyr Cys(O) NH2)::CHEMBL406289 Growth factor receptor-bound protein 2 Homo sapiens 149 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129420&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309042 104021003 CHEMBL406289 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50063311 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C66H84N12O19S/c1-34(2)24-44-56(85)74-47(27-37-15-20-42(80)21-16-37)61(90)78-66(22-8-5-9-23-66)65(96)76-49(30-51(67)81)60(89)77-54(35(3)4)62(91)69-31-52(82)70-45(28-38-12-17-39-10-6-7-11-40(39)25-38)57(86)73-46(26-36-13-18-41(79)19-14-36)58(87)75-50(55(68)84)32-98(97)33-53(83)71-48(59(88)72-44)29-43(63(92)93)64(94)95/h6-7,10-21,25,34-35,43-50,54,79-80H,5,8-9,22-24,26-33H2,1-4H3,(H2,67,81)(H2,68,84)(H,69,91)(H,70,82)(H,71,83)(H,72,88)(H,73,86)(H,74,85)(H,75,87)(H,76,96)(H,77,89)(H,78,90)(H,92,93)(H,94,95)/t44-,45-,46+,47+,48+,49+,50+,54-,98?/m1/s1 SOAXVHRFUPUPAJ-OGJGZJPRSA-N 50129418 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Nal Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly Nal Tyr Cys(O) NH2)::CHEMBL411790 Growth factor receptor-bound protein 2 Homo sapiens 4860 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129418&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309121 104021001 CHEMBL411790 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50235438 CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 BZLRZJFFHMIABH-AGEHIQCHSA-N 50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide Growth factor receptor-bound protein 2 Homo sapiens 20000 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124303&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44383302 104016640 CHEMBL444114 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 50589419 CC(C)C[C@H]1NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC(C)(C)C)NC(=O)CNC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(C)C)C(N)=O InChI=1S/C60H86N12O19S/c1-30(2)21-37-49(79)68-39(23-33-13-17-35(74)18-14-33)54(84)72-60(19-9-8-10-20-60)58(90)70-41(25-44(61)75)52(82)71-47(31(3)4)55(85)63-27-45(76)65-42(26-59(5,6)7)53(83)67-38(22-32-11-15-34(73)16-12-32)50(80)69-43(48(62)78)28-92(91)29-46(77)64-40(51(81)66-37)24-36(56(86)87)57(88)89/h11-18,30-31,36-43,47,73-74H,8-10,19-29H2,1-7H3,(H2,61,75)(H2,62,78)(H,63,85)(H,64,77)(H,65,76)(H,66,81)(H,67,83)(H,68,79)(H,69,80)(H,70,90)(H,71,82)(H,72,84)(H,86,87)(H,88,89)/t37-,38+,39+,40+,41+,42-,43+,47-,92?/m1/s1 FATUOQLOUJCJQH-CBHDNGEDSA-N 50129417 (R)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys(O) NH2)::(S)-cyclic ((N-AC)Gla Leu Tyr Ach Asn Val Gly NPG Tyr Cys(O) NH2)::CHEMBL437456 Growth factor receptor-bound protein 2 Homo sapiens 75 ChEMBL 10.1016/s0960-894x(03)00385-8 10.7270/Q25Q4VGJ 12798329 Li, P; Zhang, M; Long, YQ; Peach, ML; Liu, H; Yang, D; Nicklaus, M; Roller, PP National Cancer Institute-Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129417&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 44309241 104021000 CHEMBL437456 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51153351 OC(=O)Cc1cc(=O)oc2cc(O)ccc12 InChI=1S/C11H8O5/c12-7-1-2-8-6(3-10(13)14)4-11(15)16-9(8)5-7/h1-2,4-5,12H,3H2,(H,13,14) BNHPMQBVNXMPDU-UHFFFAOYSA-N 50022182 (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid::7-hydroxycoumarin-4-acetic acid::CHEMBL12253 Growth factor receptor-bound protein 2 Homo sapiens 11300 ChEMBL 10.1021/jm980663f 10.7270/Q2D79F4B 10072676 Lee, TR; Lawrence, DS The Albert Einstein College of Medicine of Yeshiva University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022182&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5338490 103932805 CHEMBL12253 ZINC00153920 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51189820 CC(C)(NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C37H41N5O11/c1-37(2,35(51)40-29(34(49)50)18-30(38)44)42-33(48)28(17-20-11-13-21(43)14-12-20)39-32(47)27(15-16-31(45)46)41-36(52)53-19-26-24-9-5-3-7-22(24)23-8-4-6-10-25(23)26/h3-14,26-29,43H,15-19H2,1-2H3,(H2,38,44)(H,39,47)(H,40,51)(H,41,52)(H,42,48)(H,45,46)(H,49,50)/t27-,28-,29-/m0/s1 XLHAWQAGMMFFQO-AWCRTANDSA-N 50489113 CHEMBL2296610 Growth factor receptor-bound protein 2 Homo sapiens 6.3 ChEMBL 10.1007/s00044-013-0538-z 10.7270/Q2BR8W20 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50489113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50489113&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 76331266 433956378 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51210019 C[C@](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)(C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 InChI=1S/C30H36N6O14P2/c1-30(28(40)34-23(26(33)38)15-25(32)37,19-7-11-22(12-8-19)50-52(45,46)47)36-27(39)24(14-17-5-9-21(10-6-17)49-51(42,43)44)35-29(41)48-16-18-3-2-4-20(31)13-18/h2-13,23-24H,14-16,31H2,1H3,(H2,32,37)(H2,33,38)(H,34,40)(H,35,41)(H,36,39)(H2,42,43,44)(H2,45,46,47)/t23-,24-,30+/m0/s1 CAQTYJGZCGRTBL-FOUYOVOOSA-N 50497251 CHEMBL3360189 Growth factor receptor-bound protein 2 Homo sapiens 13 ChEMBL 10.1016/j.bmcl.2014.04.114 10.7270/Q2SN0CZD 24856058 Myslinski, JM; Clements, JH; Martin, SF The University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497251&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 118724112 433964516 C01167 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51210020 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42)/t21-,22-/m0/s1 XWNQRYAPQUFUMS-VXKWHMMOSA-N 50078348 CHEMBL77689::[(S)-1-[1-((S)-1,2-Dicarbamoyl-ethylcarbamoyl)-cyclohexylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 1.000000 ChEMBL 10.1016/j.bmcl.2014.04.114 10.7270/Q2SN0CZD 24856058 Myslinski, JM; Clements, JH; Martin, SF The University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078348&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10349262 103970940 CHEMBL77689 C01167 ZINC26394430 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51210021 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C27H37N6O10P/c1-3-15(2)23(26(37)31-20(24(30)35)13-22(29)34)33-25(36)21(12-16-7-9-19(10-8-16)43-44(39,40)41)32-27(38)42-14-17-5-4-6-18(28)11-17/h4-11,15,20-21,23H,3,12-14,28H2,1-2H3,(H2,29,34)(H2,30,35)(H,31,37)(H,32,38)(H,33,36)(H2,39,40,41)/t15-,20-,21-,23-/m0/s1 NIOCFHRLKNWSBD-RJCMWMPSSA-N 50060522 CHEMBL327037::[(S)-1-[(1S,2S)-1-((S)-1,2-Dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester Growth factor receptor-bound protein 2 Homo sapiens 65 ChEMBL 10.1016/j.bmcl.2014.04.114 10.7270/Q2SN0CZD 24856058 Myslinski, JM; Clements, JH; Martin, SF The University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060522&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10579932 103956268 CHEMBL327037 C01167 ZINC27108139 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51353738 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)c2ccc3c(c2)C(=O)OC32c3ccc4cc(O)ccc4c3Oc3c2ccc2cc(O)ccc32)C(N)=O)NC1=O InChI=1S/C109H132N23O25P/c1-60(2)90-102(146)129-85(58-88(135)117-45-48-153-49-50-154-59-89(136)122-78(93(110)137)19-8-9-41-118-94(138)68-31-38-75-74(57-68)105(149)156-109(75)76-39-29-66-55-69(133)32-36-72(66)91(76)155-92-73-37-33-70(134)56-67(73)30-40-77(92)109)99(143)127-82(52-61-15-4-3-5-16-61)98(142)128-84(54-63-25-28-64-17-6-7-18-65(64)51-63)97(141)125-81(22-12-44-121-108(115)116)103(147)132-47-14-24-87(132)104(148)131-46-13-23-86(131)101(145)124-80(21-11-43-120-107(113)114)95(139)123-79(20-10-42-119-106(111)112)96(140)126-83(100(144)130-90)53-62-26-34-71(35-27-62)157-158(150,151)152/h3-7,15-18,25-40,51,55-57,60,78-87,90,133-134H,8-14,19-24,41-50,52-54,58-59H2,1-2H3,(H2,110,137)(H,117,135)(H,118,138)(H,122,136)(H,123,139)(H,124,145)(H,125,141)(H,126,140)(H,127,143)(H,128,142)(H,129,146)(H,130,144)(H4,111,112,119)(H4,113,114,120)(H4,115,116,121)(H2,150,151,152)/t78-,79-,80-,81+,82-,83-,84-,85-,86-,87+,90-/m0/s1 BCECQMWEVWXYIY-PARASPEISA-N 50547624 CHEMBL4761634 Growth factor receptor-bound protein 2 Homo sapiens 400 ChEMBL 10.1016/j.bmc.2020.115711 10.7270/Q2FB56JN 33069067 Wen, J; Liao, H; Stachowski, K; Hempfling, JP; Qian, Z; Yuan, C; Foster, MP; Pei, D The Ohio State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50547624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50547624&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 162660105 461691387 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51353739 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)c2ccc3c(c2)C(=O)OC32c3ccc4cc(O)ccc4c3Oc3c2ccc2cc(O)ccc32)C(N)=O)NC1=O InChI=1S/C109H131N23O22/c1-60(2)90-102(147)129-85(58-88(136)117-45-48-151-49-50-152-59-89(137)122-78(93(110)138)19-8-9-41-118-94(139)68-31-38-75-74(57-68)105(150)154-109(75)76-39-29-66-55-70(134)34-36-72(66)91(76)153-92-73-37-35-71(135)56-67(73)30-40-77(92)109)99(144)127-82(52-61-15-4-3-5-16-61)98(143)128-84(54-63-25-28-64-17-6-7-18-65(64)51-63)97(142)125-81(22-12-44-121-108(115)116)103(148)132-47-14-24-87(132)104(149)131-46-13-23-86(131)101(146)124-80(21-11-43-120-107(113)114)95(140)123-79(20-10-42-119-106(111)112)96(141)126-83(100(145)130-90)53-62-26-32-69(133)33-27-62/h3-7,15-18,25-40,51,55-57,60,78-87,90,133-135H,8-14,19-24,41-50,52-54,58-59H2,1-2H3,(H2,110,138)(H,117,136)(H,118,139)(H,122,137)(H,123,140)(H,124,146)(H,125,142)(H,126,141)(H,127,144)(H,128,143)(H,129,147)(H,130,145)(H4,111,112,119)(H4,113,114,120)(H4,115,116,121)/t78-,79-,80-,81+,82-,83-,84-,85-,86-,87+,90-/m0/s1 WRXQIVSHTGOIJJ-PARASPEISA-N 50547625 CHEMBL4751079 Growth factor receptor-bound protein 2 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2020.115711 10.7270/Q2FB56JN 33069067 Wen, J; Liao, H; Stachowski, K; Hempfling, JP; Qian, Z; Yuan, C; Foster, MP; Pei, D The Ohio State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50547625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50547625&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 162651814 461691388 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51353740 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)c2ccc3c(c2)C(=O)OC32c3ccc4cc(O)ccc4c3Oc3c2ccc2cc(O)ccc32)C(N)=O)NC1=O InChI=1S/C96H119N20O25P/c1-51(2)78-90(130)113-73(49-76(119)102-38-41-137-42-43-138-50-77(120)108-68(81(97)121)16-8-9-35-103-83(123)58-25-32-65-64(48-58)93(133)140-96(65)66-33-23-56-46-59(117)26-30-62(56)79(66)139-80-63-31-27-60(118)47-57(63)24-34-67(80)96)87(127)112-71(44-54-14-6-5-7-15-54)86(126)106-52(3)82(122)107-53(4)91(131)116-40-13-20-75(116)92(132)115-39-12-19-74(115)89(129)110-70(18-11-37-105-95(100)101)84(124)109-69(17-10-36-104-94(98)99)85(125)111-72(88(128)114-78)45-55-21-28-61(29-22-55)141-142(134,135)136/h5-7,14-15,21-34,46-48,51-53,68-75,78,117-118H,8-13,16-20,35-45,49-50H2,1-4H3,(H2,97,121)(H,102,119)(H,103,123)(H,106,126)(H,107,122)(H,108,120)(H,109,124)(H,110,129)(H,111,125)(H,112,127)(H,113,130)(H,114,128)(H4,98,99,104)(H4,100,101,105)(H2,134,135,136)/t52-,53+,68-,69-,70-,71-,72-,73-,74-,75+,78-/m0/s1 WAWFWUZOFSLAPI-NEKOHDDDSA-N 50547626 CHEMBL4760821 Growth factor receptor-bound protein 2 Homo sapiens 100 ChEMBL 10.1016/j.bmc.2020.115711 10.7270/Q2FB56JN 33069067 Wen, J; Liao, H; Stachowski, K; Hempfling, JP; Qian, Z; Yuan, C; Foster, MP; Pei, D The Ohio State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50547626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50547626&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 162657844 461691389 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437947 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C(O)=O)C(O)=O InChI=1S/C41H46N4O10/c42-33(46)22-32-37(50)43-23-24(20-28-11-7-10-25-9-2-3-12-29(25)28)8-6-13-30(26-14-16-27(17-15-26)35(38(51)52)39(53)54)31(21-34(47)48)36(49)45-41(40(55)44-32)18-4-1-5-19-41/h2-3,6-7,9-17,24,30-32,35H,1,4-5,8,18-23H2,(H2,42,46)(H,43,50)(H,44,55)(H,45,49)(H,47,48)(H,51,52)(H,53,54)/b13-6+/t24-,30+,31-,32-/m0/s1 FYIJOFSDJMOTGX-SPRVXXEPSA-N 50580855 CHEMBL1205233 Growth factor receptor-bound protein 2 Homo sapiens 4.3 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50580855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50580855&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10372914 476025860 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437948 NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C38H43N5O11/c39-29(44)21-28(31(45)40-19-7-11-24-10-6-9-23-8-2-3-12-26(23)24)42-37(54)38(17-4-1-5-18-38)43-32(46)27(41-33(47)36(52)53)20-22-13-15-25(16-14-22)30(34(48)49)35(50)51/h2-3,6,8-10,12-16,27-28,30H,1,4-5,7,11,17-21H2,(H2,39,44)(H,40,45)(H,41,47)(H,42,54)(H,43,46)(H,48,49)(H,50,51)(H,52,53)/t27-,28-/m0/s1 ZOJQPGFTWKKVQO-NSOVKSMOSA-N 50085867 2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)propylamino)-1,4-dioxobutan-2-ylcarbamoyl)cyclohexylamino)-2-(carboxyformamido)-3-oxopropyl)phenyl)malonic acid::2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{(S)-1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::2-{4-[2-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(oxalyl-amino)-ethyl]-phenyl}-malonic acid::CHEMBL303150 Growth factor receptor-bound protein 2 Homo sapiens 22 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085867&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9896853 103985277 CHEMBL303150 ZINC95610086 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437949 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 20 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437950 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1 YWOITRAWXNSFNB-FETINEJHSA-N 50139763 CHEMBL306657::[(E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-10-(4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid::[(E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-10-((1S,4S)-4-phosphonomethyl-phenyl)-7,16,19-triaza-spiro[5.14]icos-11-en-9-yl]-acetic acid Growth factor receptor-bound protein 2 Homo sapiens 2.0 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139763&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10259481 104029592 CHEMBL306657 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437951 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 350 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437952 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CC(O)=O)cc1 InChI=1S/C38H44N4O6/c39-33(43)23-32-36(47)40-24-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)21-35(45)46)22-34(44)42-38(37(48)41-32)18-4-1-5-19-38/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,39,43)(H,40,47)(H,41,48)(H,42,44)(H,45,46)/b11-6+/t26-,29-,32-/m0/s1 ZYRZDVCTSBJOQD-GZNVFMSSSA-N 50580856 CHEMBL5074481 Growth factor receptor-bound protein 2 Homo sapiens 740 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50580856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50580856&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search ZLY 7MPH 156599548 476025861 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437953 COC(=O)Cc1ccc(cc1)[C@@H]1CC(=O)NC2(CCCCC2)C(=O)N[C@@H](CC(N)=O)C(=O)NC[C@H](Cc2cccc3ccccc23)C\C=C\1 InChI=1S/C39H46N4O6/c1-49-36(46)22-26-15-17-28(18-16-26)30-12-7-9-27(21-31-13-8-11-29-10-3-4-14-32(29)31)25-41-37(47)33(24-34(40)44)42-38(48)39(43-35(45)23-30)19-5-2-6-20-39/h3-4,7-8,10-18,27,30,33H,2,5-6,9,19-25H2,1H3,(H2,40,44)(H,41,47)(H,42,48)(H,43,45)/b12-7+/t27-,30-,33-/m0/s1 KFBDGZKVGLDFAC-KSZOBEKFSA-N 50580857 CHEMBL5088383 Growth factor receptor-bound protein 2 Homo sapiens >20000 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50580857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50580857&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 166632651 476025862 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437954 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 InChI=1S/C37H45N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1 RHYFMOCFCFUTNH-GZNVFMSSSA-N 50102025 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID::CHEMBL291678::[(R)-4-((E)-(S)-18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,20-dioxo-17-(S)-oxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-((10R,16S)-18-(S)-1-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid::[4-(18-Carbamoylmethyl-14-naphthalen-1-ylmethyl-8,17,20-trioxo-7,16,19-triaza-spiro[5.14]icos-11-en-10-yl)-benzyl]-phosphonic acid Growth factor receptor-bound protein 2 Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102025&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search DTF 1X0N 657098 103998586 CHEMBL291678 ZINC29552795 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437955 NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CC(O)=O)cc1 InChI=1S/C38H44N4O6/c39-33(43)23-32-36(47)40-24-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)21-35(45)46)22-34(44)42-38(37(48)41-32)18-4-1-5-19-38/h2-3,6-7,9-17,26,29,32H,1,4-5,8,18-24H2,(H2,39,43)(H,40,47)(H,41,48)(H,42,44)(H,45,46)/b11-6+/t26-,29-,32-/m0/s1 ZYRZDVCTSBJOQD-GZNVFMSSSA-N 50580856 CHEMBL5074481 Growth factor receptor-bound protein 2 Homo sapiens 140 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50580856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50580856&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search ZLY 7MPH 156599548 476025861 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437956 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C21H32N5O9P/c1-4-11(2)18(21(31)25-15(19(23)29)10-17(22)28)26-20(30)16(24-12(3)27)9-13-5-7-14(8-6-13)35-36(32,33)34/h5-8,11,15-16,18H,4,9-10H2,1-3H3,(H2,22,28)(H2,23,29)(H,24,27)(H,25,31)(H,26,30)(H2,32,33,34)/t11-,15-,16-,18-/m0/s1 OWGDZTBZWQPSHR-SLBDDTMCSA-N 50060523 CHEMBL118574::Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(1S,2S)-1-((S)-1,2-dicarbamoyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-ethyl}-phenyl) ester Growth factor receptor-bound protein 2 Homo sapiens 8640 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060523&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 10816029 103956269 CHEMBL118574 C01167 ZINC27108130 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059 51437957 CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 InChI=1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30-/m0/s1 ATTZUIWVKJIUFV-KYJUHHDHSA-N 50072862 CHEMBL117807::Phosphoric acid mono-[4-((S)-2-acetylamino-2-{1-[(S)-2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester::Phosphoric acid mono-[4-(2-acetylamino-2-{(S)-1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-ethyl)-phenyl] ester Growth factor receptor-bound protein 2 Homo sapiens 47 ChEMBL 10.1016/j.bmcl.2021.128354 10.7270/Q2CR5Z6S 34506932 Xiao, T; Sun, L; Zhang, M; Li, Z; Haura, EB; Schonbrunn, E; Ji, H H. Lee Moffitt Cancer Center and Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=52&target=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072862&enzyme=Growth+factor+receptor-bound+protein+2&column=ki&startPg=0&Increment=50&submit=Search 9987342 103966453 CHEMBL117807 C01167 ZINC27102270 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 1CJ1,1FHS,1FYR,1GCQ,1GFC,1GFD,1GRI,1IO6,1QG1,1TZE,1X0N,1ZFP,2AOA,2AOB,2H46,2H5K,2HUW,2VVK,3C7I,3IMD,3IMJ,3IN7,3IN8,3KFJ,3MXC,3MXY,3N7Y,3N84,3N8M,3OV1,3OVE,3S8L,3S8N,3S8O,4P9V,4P9Z,6VK2,6WM1,6WO2,7MPH,8DGO Growth factor receptor-bound protein 2 GRB2_HUMAN P62993 P29354 Q14450 Q63057 Q63059