BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50927240 CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCNCC1 InChI=1S/C21H26N8S/c1-30-16-5-3-2-4-15(16)26-20-17-18(19(25-13-24-17)23-12-14-6-7-14)27-21(28-20)29-10-8-22-9-11-29/h2-5,13-14,22H,6-12H2,1H3,(H,23,24,25)(H,26,27,28) HFLMLZKGLUEWBU-UHFFFAOYSA-N 50380246 CHEMBL2017214 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/ml200070g 10.7270/Q2NZ88N1 24900346 Maryanoff, BE; McComsey, DF; Yabut, SC; Luci, DK; Jordan, AD; Masucci, JA; Jones, WJ; Abad, MC; Gibbs, AC; Petrounia, I TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380246&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search XNB 3Q92 53348216 160859329 CHEMBL2017214 ZINC72316202 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 50518251 OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)C1(O)CCC1 InChI=1S/C19H16ClNO3/c20-16-9-17-14(15(10-21-17)18(22)23)8-13(16)11-2-4-12(5-3-11)19(24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2,(H,22,23) FHQXLWCFSUSXBF-UHFFFAOYSA-N 237920 US9394285, 1 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.6b00866 10.7270/Q2PZ5BRC 27490827 Cameron, KO; Kung, DW; Kalgutkar, AS; Kurumbail, RG; Miller, R; Salatto, CT; Ward, J; Withka, JM; Bhattacharya, SK; Boehm, M; Borzilleri, KA; Brown, JA; Calabrese, M; Caspers, NL; Cokorinos, E; Conn, EL; Dowling, MS; Edmonds, DJ; Eng, H; Fernando, DP; Frisbie, R; Hepworth, D; Landro, J; Mao, Y; Rajamohan, F; Reyes, AR; Rose, CR; Ryder, T; Shavnya, A; Smith, AC; Tu, M; Wolford, AC; Xiao, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237920&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 6VT 5KQ5 71748255 340131342 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 50521694 O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2cc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1c(O)cccc1O InChI=1S/C25H21ClN2O6/c26-15-9-17-16(27-25(28-17)34-21-11-33-23-20(31)10-32-24(21)23)8-14(15)12-4-6-13(7-5-12)22-18(29)2-1-3-19(22)30/h1-9,20-21,23-24,29-31H,10-11H2,(H,27,28)/t20-,21-,23-,24-/m1/s1 MMOYHXCYJWHUCI-LUGTWXOSSA-N 50195534 CHEMBL3957286 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens 2.0 ChEMBL 10.1016/j.bmcl.2016.09.065 10.7270/Q25M67PH 27727125 Cameron, KO; Kurumbail, RG Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195534&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 118640135 375977210 CHEMBL3957286 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 50767828 Cc1ccc(Oc2nc3cc(c(Cl)cc3[nH]2)-c2ccc(cc2)-c2ccccc2)cc1C(O)=O InChI=1S/C27H19ClN2O3/c1-16-7-12-20(13-21(16)26(31)32)33-27-29-24-14-22(23(28)15-25(24)30-27)19-10-8-18(9-11-19)17-5-3-2-4-6-17/h2-15H,1H3,(H,29,30)(H,31,32) FIKQZQDYGXAUHC-UHFFFAOYSA-N 50246120 CHEMBL4082745 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens 39 ChEMBL 10.1021/acs.jmedchem.7b01344 10.7270/Q2V69N0Q 29035567 Lan, P; Romero, FA; Wodka, D; Kassick, AJ; Dang, Q; Gibson, T; Cashion, D; Zhou, G; Chen, Y; Zhang, X; Zhang, A; Li, Y; Trujillo, ME; Shao, Q; Wu, M; Xu, S; He, H; MacKenna, D; Staunton, J; Chapman, KT; Weber, A; Sebhat, IK; Makara, GM Metabasis Therapeutics Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246120&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 45256689 401960398 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129143 OC(=O)c1c[nH]c2cc(F)c(-c3ccc(cc3)[C@@H]3CCCCO3)c(F)c12 InChI=1S/C20H17F2NO3/c21-14-9-15-18(13(10-23-15)20(24)25)19(22)17(14)12-6-4-11(5-7-12)16-3-1-2-8-26-16/h4-7,9-10,16,23H,1-3,8H2,(H,24,25)/t16-/m0/s1 JQJNGAWEMYQJIQ-INIZCTEOSA-N 50244667 CHEMBL4105032 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50244667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50244667&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 121396404 386403209 CHEMBL4105032 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129145 COc1nc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(O)=O)N(C)C InChI=1S/C17H16ClN3O3/c1-21(2)15-5-4-9(16(20-15)24-3)10-6-11-12(17(22)23)8-19-14(11)7-13(10)18/h4-8,19H,1-3H3,(H,22,23) MJHBRTGGZYSCHJ-UHFFFAOYSA-N 238079 US9394285, 173 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=238079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=238079&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 75O 5T5T 71767991 340131496 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129158 OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)C1(O)CCC1 InChI=1S/C19H16ClNO3/c20-16-9-17-14(15(10-21-17)18(22)23)8-13(16)11-2-4-12(5-3-11)19(24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2,(H,22,23) FHQXLWCFSUSXBF-UHFFFAOYSA-N 237920 US9394285, 1 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237920&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search 6VT 5KQ5 71748255 340131342 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129159 O[C@@H]1[C@@H](O)[C@H](OC(=O)c2c[nH]c3cc(Cl)c(cc23)-c2ccc(cc2)C2(O)CCC2)O[C@@H]([C@H]1O)C(O)=O InChI=1S/C25H24ClNO9/c26-16-9-17-14(8-13(16)11-2-4-12(5-3-11)25(34)6-1-7-25)15(10-27-17)23(33)36-24-20(30)18(28)19(29)21(35-24)22(31)32/h2-5,8-10,18-21,24,27-30,34H,1,6-7H2,(H,31,32)/t18-,19-,20+,21-,24-/m0/s1 LTLTUJCGZGVBTO-DCIKREJASA-N 50463100 CHEMBL4249790 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463100&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search HTV 6E4T 121396411 433930365 C03033 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129160 COc1nc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(=O)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)N(C)C InChI=1S/C23H24ClN3O9/c1-27(2)15-5-4-9(20(26-15)34-3)10-6-11-12(8-25-14(11)7-13(10)24)22(33)36-23-18(30)16(28)17(29)19(35-23)21(31)32/h4-8,16-19,23,25,28-30H,1-3H3,(H,31,32)/t16-,17-,18+,19-,23-/m0/s1 YJKYSCKYOBZSRV-ZFXLNCEJSA-N 50463101 CHEMBL4250253 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463101&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search HU7 6E4U 121396412 433930366 C03033 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9 51129161 O[C@@H]1[C@@H](O)[C@H](OC(=O)c2c[nH]c3cc(F)c(c(F)c23)-c2ccc(cc2)[C@@H]2CCCCO2)O[C@@H]([C@H]1O)C(O)=O InChI=1S/C26H25F2NO9/c27-14-9-15-18(19(28)17(14)12-6-4-11(5-7-12)16-3-1-2-8-36-16)13(10-29-15)25(35)38-26-22(32)20(30)21(31)23(37-26)24(33)34/h4-7,9-10,16,20-23,26,29-32H,1-3,8H2,(H,33,34)/t16-,20-,21-,22+,23-,26-/m0/s1 GZCJKJJWOUAGMR-WBTGXFMPSA-N 50463099 CHEMBL4246000 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens >40000 ChEMBL 10.1021/acs.jmedchem.8b00807 10.7270/Q2Q242WT 30036059 Ryder, TF; Calabrese, MF; Walker, GS; Cameron, KO; Reyes, AR; Borzilleri, KA; Delmore, J; Miller, R; Kurumbail, RG; Ward, J; Kung, DW; Brown, JA; Edmonds, DJ; Eng, H; Wolford, AC; Kalgutkar, AS Pfizer Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=4374&target=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463099&enzyme=5%27-AMP-activated+protein+kinase+subunit+gamma-1&column=ki&startPg=0&Increment=50&submit=Search HUG 6E4W 121396405 433930364 C03033 1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 2UV4,2UV5,4CFE,4CFF,4RER,4REW,4ZHX,5EZV,5ISO,6B1U,6B2E,6C9F,6C9G,6C9H,6C9J,7JHG,7JHH,7JIJ,7M74,7MYJ 5'-AMP-activated protein kinase subunit gamma-1 AAKG1_HUMAN P54619 B4DDT7 Q8N7V9