BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
489706	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-14-12-22(13-15-23)21(2)40)30-11-6-5-10-29(30)38(34(28)43)18-26-24-8-7-9-27(35)25(24)16-17-31(26)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28-/m0/s1	FCBDCRIHHVUGDE-MMTVBGGISA-N	243167	US10053431, 69f::US10053431, 69m	E3 ubiquitin-protein ligase XIAP [241-356]			 49400					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243167&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077140	376221553							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489708	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C34H32F2N4O5/c1-20(37-3)31(42)38-27-19-40(32(43)24-14-12-22(13-15-24)21(2)41)29-11-7-6-10-28(29)39(33(27)44)18-26-25-9-5-4-8-23(25)16-17-30(26)45-34(35)36/h4-17,20,27,34,37H,18-19H2,1-3H3,(H,38,42)/t20-,27-/m0/s1	KWNFZHZGDAFIFB-DCFHFQCYSA-N	243163	US10053431, 69b::US10053431, 69n	E3 ubiquitin-protein ligase XIAP [241-356]			 25850					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243163&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076623	376221549							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489710	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H33BrN4O4/c1-20-9-11-22(12-10-20)32(40)38-19-27(36-31(39)21(2)35-3)33(41)37(28-7-5-6-8-29(28)38)18-26-25-15-14-24(34)17-23(25)13-16-30(26)42-4/h5-17,21,27,35H,18-19H2,1-4H3,(H,36,39)/t21-,27-/m0/s1	KTHDFFITHWGQIL-IDISGSTGSA-N	50441833	CHEMBL2436334::US10053431, 75b	E3 ubiquitin-protein ligase XIAP [241-356]			 30290					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441833&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711479	175454150		CHEMBL2436334				ZINC96285540	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489712	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccno2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C29H28BrN5O5/c1-17(31-2)27(36)33-22-16-35(29(38)26-12-13-32-40-26)24-7-5-4-6-23(24)34(28(22)37)15-21-20-10-9-19(30)14-18(20)8-11-25(21)39-3/h4-14,17,22,31H,15-16H2,1-3H3,(H,33,36)/t17-,22-/m0/s1	SZQOWYNAFZTCMS-JTSKRJEESA-N	243177	US10053431, 75c	E3 ubiquitin-protein ligase XIAP [241-356]			 30430					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243177&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077244	376221561							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489714	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C2CCOCC2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C31H35BrN4O5/c1-19(33-2)29(37)34-25-18-36(30(38)20-12-14-41-15-13-20)27-7-5-4-6-26(27)35(31(25)39)17-24-23-10-9-22(32)16-21(23)8-11-28(24)40-3/h4-11,16,19-20,25,33H,12-15,17-18H2,1-3H3,(H,34,37)/t19-,25-/m0/s1	IQUWZXYBQGCQKJ-DFBJGRDBSA-N	50441818	CHEMBL2436213::US10053431, 75d	E3 ubiquitin-protein ligase XIAP [241-356]			 18190					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441818&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711928	175454135		CHEMBL2436213				ZINC96285526	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489716	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C28H31BrN4O6S/c1-17(30-2)27(35)31-22-15-32(26(34)16-40(4,37)38)23-7-5-6-8-24(23)33(28(22)36)14-21-20-11-10-19(29)13-18(20)9-12-25(21)39-3/h5-13,17,22,30H,14-16H2,1-4H3,(H,31,35)/t17-,22-/m0/s1	ADRJVDXZPHWNKH-JTSKRJEESA-N	50441810	CHEMBL2436215::US10053431, 76b	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441810&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711932	175454127		CHEMBL2436215				ZINC96285518	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489718	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cnccn2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C30H29BrN6O4/c1-18(32-2)28(38)35-24-17-37(29(39)23-15-33-12-13-34-23)26-7-5-4-6-25(26)36(30(24)40)16-22-21-10-9-20(31)14-19(21)8-11-27(22)41-3/h4-15,18,24,32H,16-17H2,1-3H3,(H,35,38)/t18-,24-/m0/s1	WNFDOEFATWINQC-UUOWRZLLSA-N	50441828	CHEMBL2436211::US10053431, 76c	E3 ubiquitin-protein ligase XIAP [241-356]			 45890					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441828&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711724	175454145		CHEMBL2436211				ZINC96285535	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489720	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(NC(C)=O)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H34BrN5O5/c1-20(36-3)32(42)38-28-19-40(33(43)22-9-13-25(14-10-22)37-21(2)41)30-8-6-5-7-29(30)39(34(28)44)18-27-26-15-12-24(35)17-23(26)11-16-31(27)45-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)(H,38,42)/t20-,28-/m0/s1	LZVAKEDICCBHKT-MMTVBGGISA-N	243181	US10053431, 76d	E3 ubiquitin-protein ligase XIAP [241-356]			 33250					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243181&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077111	376221565							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489722	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccn(C)n2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C30H31BrN6O4/c1-18(32-2)28(38)33-24-17-37(29(39)23-13-14-35(3)34-23)26-8-6-5-7-25(26)36(30(24)40)16-22-21-11-10-20(31)15-19(21)9-12-27(22)41-4/h5-15,18,24,32H,16-17H2,1-4H3,(H,33,38)/t18-,24-/m0/s1	AEUZTKWFOPUNTM-UUOWRZLLSA-N	243182	US10053431, 76e	E3 ubiquitin-protein ligase XIAP [241-356]			 33720					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243182&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077064	376221566							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489724	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccnc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C31H30BrN5O4/c1-19(33-2)29(38)35-25-18-37(30(39)21-7-6-14-34-16-21)27-9-5-4-8-26(27)36(31(25)40)17-24-23-12-11-22(32)15-20(23)10-13-28(24)41-3/h4-16,19,25,33H,17-18H2,1-3H3,(H,35,38)/t19-,25-/m0/s1	RBSVEPCXJWZPIY-DFBJGRDBSA-N	50441819	CHEMBL2436209::US10053431, 89b	E3 ubiquitin-protein ligase XIAP [241-356]			 17010					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441819&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711720	175454136		CHEMBL2436209				ZINC96285527	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489726	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccccn2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H32BrN5O4/c1-20(34-2)31(40)36-26-19-37(30(39)17-23-8-6-7-15-35-23)27-9-4-5-10-28(27)38(32(26)41)18-25-24-13-12-22(33)16-21(24)11-14-29(25)42-3/h4-16,20,26,34H,17-19H2,1-3H3,(H,36,40)/t20-,26-/m0/s1	FFVWHZRSFAVZOH-FNZWTVRRSA-N	243184	US10053431, 89c	E3 ubiquitin-protein ligase XIAP [241-356]			 49900					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243184&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076562	376221568							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489728	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccc(Cl)nc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H31BrClN5O4/c1-19(35-2)31(41)37-25-18-38(30(40)14-20-8-13-29(34)36-16-20)26-6-4-5-7-27(26)39(32(25)42)17-24-23-11-10-22(33)15-21(23)9-12-28(24)43-3/h4-13,15-16,19,25,35H,14,17-18H2,1-3H3,(H,37,41)/t19-,25-/m0/s1	HFZIOLXJKCBQDO-DFBJGRDBSA-N	243185	US10053431, 89d	E3 ubiquitin-protein ligase XIAP [241-356]			 24770					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243185&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552258	376221569							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489730	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cnn(C)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C30H31BrN6O4/c1-18(32-2)28(38)34-24-17-37(29(39)20-14-33-35(3)15-20)26-8-6-5-7-25(26)36(30(24)40)16-23-22-11-10-21(31)13-19(22)9-12-27(23)41-4/h5-15,18,24,32H,16-17H2,1-4H3,(H,34,38)/t18-,24-/m0/s1	XILMXZIFBUSEOU-UUOWRZLLSA-N	243186	US10053431, 89e	E3 ubiquitin-protein ligase XIAP [241-356]			 32450					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243186&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077045	376221570							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489732	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(F)c2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H30BrFN4O4/c1-19(35-2)30(39)36-26-18-38(31(40)21-7-6-8-23(34)16-21)28-10-5-4-9-27(28)37(32(26)41)17-25-24-13-12-22(33)15-20(24)11-14-29(25)42-3/h4-16,19,26,35H,17-18H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	BBDAMYDQPOZZEU-SIBVEZHUSA-N	50441817	CHEMBL2436332::US10053431, 90b	E3 ubiquitin-protein ligase XIAP [241-356]			 26960					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441817&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711253	175454134		CHEMBL2436332				ZINC96285525	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489734	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(c2)C#N)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H30BrN5O4/c1-20(36-2)31(40)37-27-19-39(32(41)23-8-6-7-21(15-23)17-35)29-10-5-4-9-28(29)38(33(27)42)18-26-25-13-12-24(34)16-22(25)11-14-30(26)43-3/h4-16,20,27,36H,18-19H2,1-3H3,(H,37,40)/t20-,27-/m0/s1	WBUFZQQQUGFIQL-DCFHFQCYSA-N	243188	US10053431, 90c	E3 ubiquitin-protein ligase XIAP [241-356]			 21850					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243188&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076676	376221572							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489736	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H33BrN4O6S/c1-20(35-2)31(39)36-27-19-38(32(40)21-9-13-24(14-10-21)45(4,42)43)29-8-6-5-7-28(29)37(33(27)41)18-26-25-15-12-23(34)17-22(25)11-16-30(26)44-3/h5-17,20,27,35H,18-19H2,1-4H3,(H,36,39)/t20-,27-/m0/s1	ODNRMXZHMWXBTG-DCFHFQCYSA-N	50441832	CHEMBL2436205::US10053431, 90d	E3 ubiquitin-protein ligase XIAP [241-356]			 25660					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441832&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711481	175454149		CHEMBL2436205				ZINC96285539	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489738	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCOC)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C29H33BrN4O5/c1-18(31-2)28(36)32-23-17-33(27(35)13-14-38-3)24-7-5-6-8-25(24)34(29(23)37)16-22-21-11-10-20(30)15-19(21)9-12-26(22)39-4/h5-12,15,18,23,31H,13-14,16-17H2,1-4H3,(H,32,36)/t18-,23-/m0/s1	OSTWQFDDJBZQBY-MBSDFSHPSA-N	243190	US10053431, 90e	E3 ubiquitin-protein ligase XIAP [241-356]			 48560					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243190&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076761	376221574							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489740	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2C#N)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H30BrN5O4/c1-20(36-2)31(40)37-27-19-39(32(41)25-9-5-4-8-22(25)17-35)29-11-7-6-10-28(29)38(33(27)42)18-26-24-14-13-23(34)16-21(24)12-15-30(26)43-3/h4-16,20,27,36H,18-19H2,1-3H3,(H,37,40)/t20-,27-/m0/s1	HDONNVBOHIVUBU-DCFHFQCYSA-N	243191	US10053431, 90f	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243191&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077067	376221575							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489742	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C27H29BrN4O4/c1-16(29-3)26(34)30-22-15-31(17(2)33)23-7-5-6-8-24(23)32(27(22)35)14-21-20-11-10-19(28)13-18(20)9-12-25(21)36-4/h5-13,16,22,29H,14-15H2,1-4H3,(H,30,34)/t16-,22-/m0/s1	PBAVHKPUMOQYFD-AOMKIAJQSA-N	50441811	CHEMBL2436214::US10053431, 91b	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441811&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711930	175454128		CHEMBL2436214				ZINC96285519	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489744	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C)o2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C31H31BrN4O5/c1-18-9-13-28(41-18)31(39)36-17-24(34-29(37)19(2)33-3)30(38)35(25-7-5-6-8-26(25)36)16-23-22-12-11-21(32)15-20(22)10-14-27(23)40-4/h5-15,19,24,33H,16-17H2,1-4H3,(H,34,37)/t19-,24-/m0/s1	DFEWVWLUJFZIAY-CYFREDJKSA-N	50441831	CHEMBL2436212::US10053431, 91c	E3 ubiquitin-protein ligase XIAP [241-356]			 30570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441831&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711926	175454148		CHEMBL2436212				ZINC96285538	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489746	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(F)(F)F)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H30BrF3N4O4/c1-19(38-2)30(42)39-26-18-41(31(43)20-8-11-22(12-9-20)33(35,36)37)28-7-5-4-6-27(28)40(32(26)44)17-25-24-14-13-23(34)16-21(24)10-15-29(25)45-3/h4-16,19,26,38H,17-18H2,1-3H3,(H,39,42)/t19-,26-/m0/s1	ZKGFDAFPIRQCGA-SIBVEZHUSA-N	243194	US10053431, 91d	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243194&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077119	376221578							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489748	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2nnn[nH]2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			243195	US10053431, 96b	E3 ubiquitin-protein ligase XIAP [241-356]			 38810					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243195&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077183	376221579							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489750	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC2CCOCC2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H38N4O4/c1-21-12-13-24-8-4-5-9-25(24)26(21)19-36-29-11-7-6-10-28(29)35(30(37)18-23-14-16-40-17-15-23)20-27(32(36)39)34-31(38)22(2)33-3/h4-13,22-23,27,33H,14-20H2,1-3H3,(H,34,38)/t22-,27-/m0/s1	FKPUSQNNSDNGBB-CUNXSJBXSA-N	243196	US10053431, 96c	E3 ubiquitin-protein ligase XIAP [241-356]			 28120					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243196&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076528	376221580							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489752	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H31N5O3/c1-21-12-15-24-8-4-5-9-26(24)27(21)19-37-29-10-6-7-11-30(29)38(32(40)25-16-13-23(18-34)14-17-25)20-28(33(37)41)36-31(39)22(2)35-3/h4-17,22,28,35H,19-20H2,1-3H3,(H,36,39)/t22-,28-/m0/s1	FWJQHHBSVNLJBA-DWACAAAGSA-N	243197	US10053431, 96d	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243197&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077170	376221581							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489754	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC2CCCCC2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H40N4O3/c1-22-17-18-25-13-7-8-14-26(25)27(22)20-37-30-16-10-9-15-29(30)36(31(38)19-24-11-5-4-6-12-24)21-28(33(37)40)35-32(39)23(2)34-3/h7-10,13-18,23-24,28,34H,4-6,11-12,19-21H2,1-3H3,(H,35,39)/t23-,28-/m0/s1	JWZHGQQKGZBONI-FIPFOOKPSA-N	243198	US10053431, 96e	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243198&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077049	376221582							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489756	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(Cl)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H31ClN4O3/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-36-28-10-6-7-11-29(28)37(31(39)23-14-16-24(33)17-15-23)19-27(32(36)40)35-30(38)21(2)34-3/h4-17,21,27,34H,18-19H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	YXTJOFXWLBJVQR-IDISGSTGSA-N	243199	US10053431, 96f	E3 ubiquitin-protein ligase XIAP [241-356]			 32790					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243199&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077336	376221583							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489244	CN[C@@H](C)C(=O)N[C@H]1CNc2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C24H26N4O2/c1-16(25-2)23(29)27-21-14-26-20-12-5-6-13-22(20)28(24(21)30)15-18-10-7-9-17-8-3-4-11-19(17)18/h3-13,16,21,25-26H,14-15H2,1-2H3,(H,27,29)/t16-,21-/m0/s1	PVVQVXNDKFTIGZ-KKSFZXQISA-N	50441803	CHEMBL2436228::US10053431, 1	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441803&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72713606	175454120		CHEMBL2436228				ZINC96285511	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489246	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(c2)C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H34N4O4/c1-21-16-17-24-10-5-6-13-27(24)28(21)19-37-30-14-7-8-15-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)26-12-9-11-25(18-26)23(3)39/h5-18,22,29,35H,19-20H2,1-4H3,(H,36,40)/t22-,29-/m0/s1	KINJENSJGPVWTP-ZTOMLWHTSA-N	238896	US10053431, 96g	E3 ubiquitin-protein ligase XIAP [241-356]			 44820					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=238896	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=238896&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076660	376221339							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489248	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C26H28N4O3/c1-17(27-3)25(32)28-22-16-29(18(2)31)23-13-6-7-14-24(23)30(26(22)33)15-20-11-8-10-19-9-4-5-12-21(19)20/h4-14,17,22,27H,15-16H2,1-3H3,(H,28,32)/t17-,22-/m0/s1	IYIIWFZSANEUHR-JTSKRJEESA-N	50441802	CHEMBL2436320::US10053431, 2	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441802&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72714288	175454119		CHEMBL2436320				ZINC96285510	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489250	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccnc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O3/c1-21-14-15-24-10-4-5-11-25(24)26(21)19-37-29-13-7-6-12-28(29)36(30(38)17-23-9-8-16-34-18-23)20-27(32(37)40)35-31(39)22(2)33-3/h4-16,18,22,27,33H,17,19-20H2,1-3H3,(H,35,39)/t22-,27-/m0/s1	HYOHNXGIXPHQAC-CUNXSJBXSA-N	238898	US10053431, 96h	E3 ubiquitin-protein ligase XIAP [241-356]			 13570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=238898	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=238898&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076630	376221340							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489252	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C29H34N4O3/c1-19(2)16-27(34)32-18-24(31-28(35)20(3)30-4)29(36)33(26-15-8-7-14-25(26)32)17-22-12-9-11-21-10-5-6-13-23(21)22/h5-15,19-20,24,30H,16-18H2,1-4H3,(H,31,35)/t20-,24-/m0/s1	BLUPXWDSMIGSEC-RDPSFJRHSA-N	50441801	CHEMBL2436321::US10053431, 3	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441801&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72714290	175454118		CHEMBL2436321				ZINC96285509	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489254	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H31FN4O3/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-36-28-10-6-7-11-29(28)37(31(39)23-14-16-24(33)17-15-23)19-27(32(36)40)35-30(38)21(2)34-3/h4-17,21,27,34H,18-19H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	CMJNJLAZFRPIHF-IDISGSTGSA-N	239257	US10053431, 96i	E3 ubiquitin-protein ligase XIAP [241-356]			 47950					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239257&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077265	376221342							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489256	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccccc2)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C32H32N4O3/c1-22(33-2)31(38)34-27-21-35(30(37)19-23-11-4-3-5-12-23)28-17-8-9-18-29(28)36(32(27)39)20-25-15-10-14-24-13-6-7-16-26(24)25/h3-18,22,27,33H,19-21H2,1-2H3,(H,34,38)/t22-,27-/m0/s1	BVWILJUJLQSYCT-CUNXSJBXSA-N	239258	(S)-2-Methylamino-N—((S)-1-naphthalen-1-ylmethyl-2-oxo-5-phenylacetyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-propionamide hydrochloride::US10053431, 4	E3 ubiquitin-protein ligase XIAP [241-356]			>54000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239258&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076972	376221343							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489258	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(N)c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O3/c1-20-15-16-22-9-4-5-12-25(22)26(20)18-36-28-13-6-7-14-29(28)37(31(39)23-10-8-11-24(33)17-23)19-27(32(36)40)35-30(38)21(2)34-3/h4-17,21,27,34H,18-19,33H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	VQGSSRFNAZBYOL-IDISGSTGSA-N	239313	US10053431, 96j::US10053431, 96k	E3 ubiquitin-protein ligase XIAP [241-356]			 24570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239313&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077394	376221344							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489260	CN[C@@H](C)C(=O)N[C@H]1CN(C)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C25H28N4O2/c1-17(26-2)24(30)27-21-16-28(3)22-13-6-7-14-23(22)29(25(21)31)15-19-11-8-10-18-9-4-5-12-20(18)19/h4-14,17,21,26H,15-16H2,1-3H3,(H,27,30)/t17-,21-/m0/s1	SFOIEDLMYJHJGW-UWJYYQICSA-N	50441805	CHEMBL2436322::US10053431, 5	E3 ubiquitin-protein ligase XIAP [241-356]			>54000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441805&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72714293	175454122		CHEMBL2436322				ZINC96285513	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489262	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(N)c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O3/c1-20-15-16-22-9-4-5-12-25(22)26(20)18-36-28-13-6-7-14-29(28)37(31(39)23-10-8-11-24(33)17-23)19-27(32(36)40)35-30(38)21(2)34-3/h4-17,21,27,34H,18-19,33H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	VQGSSRFNAZBYOL-IDISGSTGSA-N	239313	US10053431, 96j::US10053431, 96k	E3 ubiquitin-protein ligase XIAP [241-356]			 32250					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239313&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077394	376221344							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489264	CN[C@@H](C)C(=O)N[C@H]1CN(CCC(C)C)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C29H36N4O2/c1-20(2)16-17-32-19-25(31-28(34)21(3)30-4)29(35)33(27-15-8-7-14-26(27)32)18-23-12-9-11-22-10-5-6-13-24(22)23/h5-15,20-21,25,30H,16-19H2,1-4H3,(H,31,34)/t21-,25-/m0/s1	HGJIBFVQRAYBID-OFVILXPXSA-N	50441804	CHEMBL2436323::US10053431, 6	E3 ubiquitin-protein ligase XIAP [241-356]			>54000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441804&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72714295	175454121		CHEMBL2436323				ZINC96285512	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489266	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(OC)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H34N4O4/c1-21-13-14-23-9-5-6-10-26(23)27(21)19-36-29-11-7-8-12-30(29)37(32(39)24-15-17-25(41-4)18-16-24)20-28(33(36)40)35-31(38)22(2)34-3/h5-18,22,28,34H,19-20H2,1-4H3,(H,35,38)/t22-,28-/m0/s1	AVQYOVIAYBZGCX-DWACAAAGSA-N	239390	US10053431, 96l	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239390&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076629	376221346							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489268	CN[C@@H](C)C(=O)N[C@H]1CN(CCc2ccccc2)c2ccccc2N(Cc2cccc3ccccc23)C1=O	InChI=1S/C32H34N4O2/c1-23(33-2)31(37)34-28-22-35(20-19-24-11-4-3-5-12-24)29-17-8-9-18-30(29)36(32(28)38)21-26-15-10-14-25-13-6-7-16-27(25)26/h3-18,23,28,33H,19-22H2,1-2H3,(H,34,37)/t23-,28-/m0/s1	VLOSAUPRZMBEGJ-FIPFOOKPSA-N	239419	(S)-2-Methylamino-N—((S)-1-naphthalen-1-ylmethyl-2-oxo-5-phenethyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-propionamide trifluoroacetate::US10053431, 7	E3 ubiquitin-protein ligase XIAP [241-356]			>54000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239419&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076678	340132697							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489270	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)NC	InChI=1S/C26H31N5O4S/c1-17-13-14-19-9-5-6-10-20(19)21(17)15-30-23-11-7-8-12-24(23)31(36(34,35)28-4)16-22(26(30)33)29-25(32)18(2)27-3/h5-14,18,22,27-28H,15-16H2,1-4H3,(H,29,32)/t18-,22-/m0/s1	UQLXBECWUIVNNI-AVRDEDQJSA-N	239445	US10053431, 98b	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239445&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077090	376221347							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489272	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C30H36N4O3/c1-19(2)16-28(35)33-18-25(32-29(36)21(4)31-5)30(37)34(27-13-9-8-12-26(27)33)17-24-20(3)14-15-22-10-6-7-11-23(22)24/h6-15,19,21,25,31H,16-18H2,1-5H3,(H,32,36)/t21-,25-/m0/s1	YJFRQTOILXCRIK-OFVILXPXSA-N	50441797	CHEMBL2436327::US10053431, 8	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441797&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72713610	175454114		CHEMBL2436327				ZINC96285504	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489274	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccc(cc1)C(C)=O	InChI=1S/C33H34N4O5S/c1-21-13-14-25-9-5-6-10-27(25)28(21)19-36-30-11-7-8-12-31(30)37(20-29(33(36)40)35-32(39)22(2)34-4)43(41,42)26-17-15-24(16-18-26)23(3)38/h5-18,22,29,34H,19-20H2,1-4H3,(H,35,39)/t22-,29-/m0/s1	OYOCBORPXQCJHB-ZTOMLWHTSA-N	239516	US10053431, 98c	E3 ubiquitin-protein ligase XIAP [241-356]			 29800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=239516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=239516&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077055	376221349							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489276	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccncc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C31H31N5O3/c1-20-12-13-22-8-4-5-9-24(22)25(20)18-35-27-10-6-7-11-28(27)36(30(38)23-14-16-33-17-15-23)19-26(31(35)39)34-29(37)21(2)32-3/h4-17,21,26,32H,18-19H2,1-3H3,(H,34,37)/t21-,26-/m0/s1	WZIJQOUXQZOANR-LVXARBLLSA-N	240239	(S)-2-Methylamino-N—[(S)-1-(2-methyl-naphthalen-1-naphthalen-1 ylmethyl)-2-oxo-5-(pyridine-4-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-propionamide hydrochloride::US10053431, 9	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=240239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=240239&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086438	376221350							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489278	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C31H31N5O6S/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-34-28-10-6-7-11-29(28)35(19-27(31(34)38)33-30(37)21(2)32-3)43(41,42)24-16-14-23(15-17-24)36(39)40/h4-17,21,27,32H,18-19H2,1-3H3,(H,33,37)/t21-,27-/m0/s1	UKJCAVJNBGIXQF-IDISGSTGSA-N	241189	US10053431, 98d	E3 ubiquitin-protein ligase XIAP [241-356]			 28970					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241189&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076823	376221351							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489280	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)COCCOC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C30H36N4O5/c1-20-13-14-22-9-5-6-10-23(22)24(20)17-34-27-12-8-7-11-26(27)33(28(35)19-39-16-15-38-4)18-25(30(34)37)32-29(36)21(2)31-3/h5-14,21,25,31H,15-19H2,1-4H3,(H,32,36)/t21-,25-/m0/s1	ZSDHXPRMBBKSNO-OFVILXPXSA-N	241191	(S)—N—[(S)-5-[2-(2-methoxy-ethoxy)-acetyl]-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 10	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241191&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077224	376221352							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489282	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccccc1	InChI=1S/C31H32N4O4S/c1-21-17-18-23-11-7-8-14-25(23)26(21)19-34-28-15-9-10-16-29(28)35(40(38,39)24-12-5-4-6-13-24)20-27(31(34)37)33-30(36)22(2)32-3/h4-18,22,27,32H,19-20H2,1-3H3,(H,33,36)/t22-,27-/m0/s1	OFVYHQRRFQEYLE-CUNXSJBXSA-N	241212	US10053431, 98e	E3 ubiquitin-protein ligase XIAP [241-356]			 31600					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241212&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076892	376221353							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489284	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(N)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C28H31N5O4/c1-17-12-13-19-8-4-5-9-20(19)21(17)15-33-24-11-7-6-10-23(24)32(26(35)14-25(29)34)16-22(28(33)37)31-27(36)18(2)30-3/h4-13,18,22,30H,14-16H2,1-3H3,(H2,29,34)(H,31,36)/t18-,22-/m0/s1	BUQBEWDAVVZXLE-AVRDEDQJSA-N	241258	(S)—N—[(S)-5-(2-Carbamoyl-acetyl)-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 11	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241258&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077074	376221354							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489286	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccc(OC)cc1	InChI=1S/C32H34N4O5S/c1-21-13-14-23-9-5-6-10-26(23)27(21)19-35-29-11-7-8-12-30(29)36(20-28(32(35)38)34-31(37)22(2)33-3)42(39,40)25-17-15-24(41-4)16-18-25/h5-18,22,28,33H,19-20H2,1-4H3,(H,34,37)/t22-,28-/m0/s1	BRVFBTWDEKUMFH-DWACAAAGSA-N	241366	US10053431, 98f	E3 ubiquitin-protein ligase XIAP [241-356]			>50000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241366&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076717	376221355							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489288	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CN2CCN(C)CC2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H40N6O3/c1-22-13-14-24-9-5-6-10-25(24)26(22)19-38-29-12-8-7-11-28(29)37(30(39)21-36-17-15-35(4)16-18-36)20-27(32(38)41)34-31(40)23(2)33-3/h5-14,23,27,33H,15-21H2,1-4H3,(H,34,40)/t23-,27-/m0/s1	GEPDCKPUAWJVJS-HOFKKMOUSA-N	241602	(S)-2-methylamino-N—{(S)-1(2-methyl-naphthalen-1-ylmethyl)-5-[2-(4-methyl-piperazin-1-yl)-acetyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl}-propionamide hydrochloride::US10053431, 12	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241602&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076813	376221356							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489290	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H35BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20-21,28,36,40H,18-19H2,1-4H3,(H,37,41)/t20-,21?,28-/m0/s1	LNZZPMFSHPPZAH-ZWCJHOFGSA-N	241607	(2S)-N-((3S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(4-(1- hydroxyethyl)benzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::BDBM242602::US10053431, 103::US10053431, 104	E3 ubiquitin-protein ligase XIAP [241-356]			 41060					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241607&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076904	376221357							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489292	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)COCCOCCOC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H40N4O6/c1-22-13-14-24-9-5-6-10-25(24)26(22)19-36-29-12-8-7-11-28(29)35(30(37)21-42-18-17-41-16-15-40-4)20-27(32(36)39)34-31(38)23(2)33-3/h5-14,23,27,33H,15-21H2,1-4H3,(H,34,38)/t23-,27-/m0/s1	VHGLIEZYKBMCEQ-HOFKKMOUSA-N	241615	(S)—N—[(S)-5-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-acetyl}-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 13	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241615&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076715	376221358							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489294	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H35BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20-21,28,36,40H,18-19H2,1-4H3,(H,37,41)/t20-,21?,28-/m0/s1	LNZZPMFSHPPZAH-ZWCJHOFGSA-N	241607	(2S)-N-((3S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(4-(1- hydroxyethyl)benzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::BDBM242602::US10053431, 103::US10053431, 104	E3 ubiquitin-protein ligase XIAP [241-356]			 47420					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241607&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076904	376221357							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489296	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C27H30N4O3/c1-17-13-14-20-9-5-6-10-21(20)22(17)15-31-25-12-8-7-11-24(25)30(19(3)32)16-23(27(31)34)29-26(33)18(2)28-4/h5-14,18,23,28H,15-16H2,1-4H3,(H,29,33)/t18-,23-/m0/s1	XGHINJSUQKBCFU-MBSDFSHPSA-N	241648	(S)—N—[(S)-5-acetyl-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 14	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241648&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086412	376221359							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489298	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(CC(=O)Nc2cccc3ccccc23)C1=O	InChI=1S/C34H33N5O5/c1-21(35-3)32(42)37-28-19-38(33(43)25-17-15-23(16-18-25)22(2)40)29-13-6-7-14-30(29)39(34(28)44)20-31(41)36-27-12-8-10-24-9-4-5-11-26(24)27/h4-18,21,28,35H,19-20H2,1-3H3,(H,36,41)(H,37,42)/t21-,28-/m0/s1	LVLHNAAVZVZZSV-KMRXNPHXSA-N	241649	(2S)-N-[(3S)-1-(4-acetylbenzoyl)-5-[2- (naphthalen-1-ylamino)-2-oxoethyl]-4- oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]- 2-(methylamino)propanamide;2,2,2- trifluoroacetic acid::US10053431, 105	E3 ubiquitin-protein ligase XIAP [241-356]			 46080					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241649&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531454	376221360							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489300	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCC(O)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C30H34N4O5/c1-19-15-16-21-9-4-5-10-22(21)23(19)17-34-26-12-7-6-11-25(26)33(27(35)13-8-14-28(36)37)18-24(30(34)39)32-29(38)20(2)31-3/h4-7,9-12,15-16,20,24,31H,8,13-14,17-18H2,1-3H3,(H,32,38)(H,36,37)/t20-,24-/m0/s1	COJWRLRWHVCSIG-RDPSFJRHSA-N	241657	5-[(S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-yl]-5-oxo-pentanoic acid hydrochloride::US10053431, 15	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241657&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076635	376221361							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489302	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(CC(=O)Nc2nccs2)C1=O	InChI=1S/C27H28N6O5S/c1-16(28-3)24(36)30-20-14-32(25(37)19-10-8-18(9-11-19)17(2)34)21-6-4-5-7-22(21)33(26(20)38)15-23(35)31-27-29-12-13-39-27/h4-13,16,20,28H,14-15H2,1-3H3,(H,30,36)(H,29,31,35)/t16-,20-/m0/s1	VOWGDTLUUUNJEC-JXFKEZNVSA-N	241658	(25)-N-[(35)-1-(4-acetylbenzoyl)-4-oxo-5- [2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;2,2,2- trifluoroacetic acid::US10053431, 106	E3 ubiquitin-protein ligase XIAP [241-356]			>51500					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241658&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531375	376221362							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489304	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCC(O)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C29H32N4O5/c1-18-12-13-20-8-4-5-9-21(20)22(18)16-33-25-11-7-6-10-24(25)32(26(34)14-15-27(35)36)17-23(29(33)38)31-28(37)19(2)30-3/h4-13,19,23,30H,14-17H2,1-3H3,(H,31,37)(H,35,36)/t19-,23-/m0/s1	LFQRRIJJVBFKIS-CVDCTZTESA-N	241671	4-[(S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-yl]-4-oxo-butyric acid hydrochloride::US10053431, 16	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241671&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076486	376221363							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489306	CN[C@@H](C)C(=O)N(C)[C@H]1CN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H32BrN5O6/c1-20(35-2)31(40)36(3)29-19-38(32(41)21-9-13-24(14-10-21)39(43)44)28-8-6-5-7-27(28)37(33(29)42)18-26-25-15-12-23(34)17-22(25)11-16-30(26)45-4/h5-17,20,29,35H,18-19H2,1-4H3/t20-,29-/m0/s1	KKYBDKUVDMXIKG-WRONEBCDSA-N	241672	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(4- nitrobenzoyl)-2-oxo-2,3,4,5-tetrahydro- 1H-benzo[b][1,4]diazepin-3-yl)-N- methyl-2-(methylamino)propanamide hydrochloride::US10053431, 107	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241672&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077151	376221364							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489308	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)NC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C27H31N5O3/c1-17-13-14-19-9-5-6-10-20(19)21(17)15-31-23-11-7-8-12-24(23)32(27(35)29-4)16-22(26(31)34)30-25(33)18(2)28-3/h5-14,18,22,28H,15-16H2,1-4H3,(H,29,35)(H,30,33)/t18-,22-/m0/s1	ZWOABPMSDSIAAD-AVRDEDQJSA-N	241682	(S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carboxylic acid methylamide hydrochloride::US10053431, 17	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241682&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077219	376221365							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489310	CN[C@@H](C)C(=O)N[C@H]1CN2c3ccccc3N(Cc3c(OC)ccc4cc(ccc34)C(=O)NCC2=O)C1=O	InChI=1S/C28H29N5O5/c1-16(29-2)26(35)31-21-15-32-22-6-4-5-7-23(22)33(28(21)37)14-20-19-10-8-18(27(36)30-13-25(32)34)12-17(19)9-11-24(20)38-3/h4-12,16,21,29H,13-15H2,1-3H3,(H,30,36)(H,31,35)/t16-,21-/m0/s1	FEKGYZNXNRHBPQ-KKSFZXQISA-N	241683	Cyclic-5-[(S)-5-(3-Amino-acetyl)-3-((S)-2- methylamino-propionylamino)-2-oxo-2,3,4,5- tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]- 6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 108	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241683&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552397	376221366							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489312	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)CS(C)(=O)=O	InChI=1S/C27H32N4O6S2/c1-18-13-14-20-9-5-6-10-21(20)22(18)15-30-24-11-7-8-12-25(24)31(39(36,37)17-38(4,34)35)16-23(27(30)33)29-26(32)19(2)28-3/h5-14,19,23,28H,15-17H2,1-4H3,(H,29,32)/t19-,23-/m0/s1	RAUKLMVKCSKQSO-CVDCTZTESA-N	241690	(S)—N—[(S)-5-Methanesulfonylmethanesulfonyl-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide trifluoroacetate::US10053431, 18	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241690&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076575	376221367							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489314	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(CC(=O)Nc2nc3ccccc3s2)C1=O	InChI=1S/C31H30N6O5S/c1-18(32-3)28(40)33-23-16-36(29(41)21-14-12-20(13-15-21)19(2)38)24-9-5-6-10-25(24)37(30(23)42)17-27(39)35-31-34-22-8-4-7-11-26(22)43-31/h4-15,18,23,32H,16-17H2,1-3H3,(H,33,40)(H,34,35,39)/t18-,23-/m0/s1	PJTRUGDAMFFNAG-MBSDFSHPSA-N	241698	(2S)-N-[(3S)-1-(4-acetylbenzoyl)-5-[2- (1,3-benzothiazol-2-ylamino)-2- oxoethyl]-4-oxo-2,3-dihydro-1,5- benzodiazepin-3-yl]-2- (methylamino)propanamide;2,2,2- trifluoroacctic acid::US10053431, 109	E3 ubiquitin-protein ligase XIAP [241-356]			 42340					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241698&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531536	376221368							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489316	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(C)(=O)=O	InChI=1S/C26H30N4O4S/c1-17-13-14-19-9-5-6-10-20(19)21(17)15-29-23-11-7-8-12-24(23)30(35(4,33)34)16-22(26(29)32)28-25(31)18(2)27-3/h5-14,18,22,27H,15-16H2,1-4H3,(H,28,31)/t18-,22-/m0/s1	JASWQEPLVCSAEY-AVRDEDQJSA-N	241699	(S)—N—[(S)-5-methanesulfonyl-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 19	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241699&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077107	376221369							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489318	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O	InChI=1S/C36H42N4O4/c1-22(37-2)33(41)38-32-34(42)39(20-28-27-9-5-4-8-26(27)12-13-31(28)44-3)29-10-6-7-11-30(29)40(35(32)43)21-36-17-23-14-24(18-36)16-25(15-23)19-36/h4-13,22-25,32,37H,14-21H2,1-3H3,(H,38,41)/t22-,23?,24?,25?,32?,36?/m0/s1	ROIZRCWZUQNFED-WQJYIYLMSA-N	241700	(2S)-N-[5-(1-adamantylmethyl)-1-[(2- methoxynaphthalen-1-yl)methyl]-2,4- dioxo-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide::US10053431, 110	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241700&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531373	376221370							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489320	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)OC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C27H30N4O4/c1-17-13-14-19-9-5-6-10-20(19)21(17)15-30-23-11-7-8-12-24(23)31(27(34)35-4)16-22(26(30)33)29-25(32)18(2)28-3/h5-14,18,22,28H,15-16H2,1-4H3,(H,29,32)/t18-,22-/m0/s1	DRJYXRCWKFVLTM-AVRDEDQJSA-N	241701	((S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carboxylic acid methyl ester hydrochloride::US10053431, 20	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241701&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077187	376221371							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489322	COc1ccc2ccccc2c1CN1c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C(=O)C(NC(=O)[C@H](C)N)C1=O	InChI=1S/C35H40N4O4/c1-21(36)32(40)37-31-33(41)38(19-27-26-8-4-3-7-25(26)11-12-30(27)43-2)28-9-5-6-10-29(28)39(34(31)42)20-35-16-22-13-23(17-35)15-24(14-22)18-35/h3-12,21-24,31H,13-20,36H2,1-2H3,(H,37,40)/t21-,22?,23?,24?,31?,35?/m0/s1	FLYPMMIOPVMWBS-LWMOJHMESA-N	242408	(2S)-N-[5-(1-adamantylmethyl)-1-[(2- methoxynaphthalen-1-yl)methyl]-2,4- dioxo-1,5-benzodiazepin-3-yl]-2- aminopropanamide::US10053431, 111	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242408&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531539	376221372					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489324	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2ccccc2)C1=O	InChI=1S/C25H32N4O3/c1-17(2)14-23(30)28-16-20(27-24(31)18(3)26-4)25(32)29(15-19-10-6-5-7-11-19)22-13-9-8-12-21(22)28/h5-13,17-18,20,26H,14-16H2,1-4H3,(H,27,31)/t18-,20-/m0/s1	IPXXXYPQWFDVHU-ICSRJNTNSA-N	50441800	CHEMBL2436324::US10053431, 21	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441800&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711021	175454117		CHEMBL2436324				ZINC96285508	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489326	CN[C@@H](C)C(=O)N[C@H]1CN2c3ccccc3N(Cc3c(OC)ccc4cc(ccc34)C(=O)N(C)CCCC2=O)C1=O	InChI=1S/C31H35N5O5/c1-19(32-2)29(38)33-24-18-35-25-8-5-6-9-26(25)36(31(24)40)17-23-22-13-11-21(16-20(22)12-14-27(23)41-4)30(39)34(3)15-7-10-28(35)37/h5-6,8-9,11-14,16,19,24,32H,7,10,15,17-18H2,1-4H3,(H,33,38)/t19-,24-/m0/s1	RTKCXJJVDINMFF-CYFREDJKSA-N	242579	Cyclic-5-[(S)-5-(3-Amino-pentanoyl)-3-((S)-2- methylamino-propionylamino)-2-oxo-2,3,4,5- tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]- 6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 112	E3 ubiquitin-protein ligase XIAP [241-356]			 41220					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242579&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552393	376221374							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489328	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2ccccc2OC)C1=O	InChI=1S/C26H34N4O4/c1-17(2)14-24(31)29-16-20(28-25(32)18(3)27-4)26(33)30(22-12-8-7-11-21(22)29)15-19-10-6-9-13-23(19)34-5/h6-13,17-18,20,27H,14-16H2,1-5H3,(H,28,32)/t18-,20-/m0/s1	HUSFXTPAUXUGAL-ICSRJNTNSA-N	242580	(S)—N—[(S)-1-(2-Methoxy-benzyl)-5-(3-methyl-butyryl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 22	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242580&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086576	376221375							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489330	CC[C@H](NC)C(=O)NC1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O	InChI=1S/C37H44N4O4/c1-4-29(38-2)34(42)39-33-35(43)40(21-28-27-10-6-5-9-26(27)13-14-32(28)45-3)30-11-7-8-12-31(30)41(36(33)44)22-37-18-23-15-24(19-37)17-25(16-23)20-37/h5-14,23-25,29,33,38H,4,15-22H2,1-3H3,(H,39,42)/t23?,24?,25?,29-,33?,37?/m0/s1	VFSUZEYGCPPYKQ-QAZDTREQSA-N	242581	(2S)-N-[5-(1-adamantylmethyl)-1-[(2- methoxynaphthalen-1-yl)methyl]-2,4- dioxo-1,5-benzodiazepin-3-yl]-2- (methylamino)butanamide::US10053431, 113	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242581&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531436	376221376							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489332	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(CCc2ccccc2)C1=O	InChI=1S/C26H34N4O3/c1-18(2)16-24(31)30-17-21(28-25(32)19(3)27-4)26(33)29(22-12-8-9-13-23(22)30)15-14-20-10-6-5-7-11-20/h5-13,18-19,21,27H,14-17H2,1-4H3,(H,28,32)/t19-,21-/m0/s1	PSGSLGLCJFCTCM-FPOVZHCZSA-N	50441799	CHEMBL2436325::US10053431, 23	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441799&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711023	175454116		CHEMBL2436325				ZINC96285507	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489334	CC[C@H](NC)C(=O)NC1C(=O)N(C)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C27H30N4O3/c1-5-21(28-3)25(32)29-24-26(33)30(4)22-12-8-9-13-23(22)31(27(24)34)16-20-17(2)14-15-18-10-6-7-11-19(18)20/h6-15,21,24,28H,5,16H2,1-4H3,(H,29,32)/t21-,24?/m0/s1	DESGHHDJGPNBIT-XEGCMXMBSA-N	242583	(2S)-N-(1-methyl-5-((2- methylnaphthalen-1-yl)methyl)-2,4- dioxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)butanamide::US10053431, 114	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242583&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531412	376221378							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489336	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C30H36N4O4/c1-19(2)16-28(35)33-18-24(32-29(36)20(3)31-4)30(37)34(26-13-9-8-12-25(26)33)17-23-22-11-7-6-10-21(22)14-15-27(23)38-5/h6-15,19-20,24,31H,16-18H2,1-5H3,(H,32,36)/t20-,24-/m0/s1	OMGSWRKTEWFWDD-RDPSFJRHSA-N	50441796	CHEMBL2436328::US10053431, 24	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441796&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711027	175454113		CHEMBL2436328				ZINC96285503	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489338	CC[C@H](NC)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C32H32N4O3/c1-4-26(33-3)30(37)34-29-31(38)35(20-25-21(2)18-19-22-12-8-9-15-24(22)25)27-16-10-11-17-28(27)36(32(29)39)23-13-6-5-7-14-23/h5-19,26,29,33H,4,20H2,1-3H3,(H,34,37)/t26-,29?/m0/s1	WQTWHRXSRYKUOM-QUWDGAPNSA-N	242585	(2S)-2-(methylamino)-N-(1-((2- methylnaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazcpin-3-yl)butanamide::US10053431, 115	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242585&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076750	376221380							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489340	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(C(C)c2cccc3ccccc23)C1=O	InChI=1S/C30H36N4O3/c1-19(2)17-28(35)33-18-25(32-29(36)20(3)31-5)30(37)34(27-16-9-8-15-26(27)33)21(4)23-14-10-12-22-11-6-7-13-24(22)23/h6-16,19-21,25,31H,17-18H2,1-5H3,(H,32,36)/t20-,21?,25-/m0/s1	DUYGVDDNRZRAPH-HAYYQKKZSA-N	50441798	CHEMBL2436326::US10053431, 25	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441798&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711025	175454115		CHEMBL2436326				ZINC96285506	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489342	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C31H30N4O3/c1-20-17-18-22-11-7-8-14-24(22)25(20)19-34-26-15-9-10-16-27(26)35(23-12-5-4-6-13-23)31(38)28(30(34)37)33-29(36)21(2)32-3/h4-18,21,28,32H,19H2,1-3H3,(H,33,36)/t21-,28?/m0/s1	SDKJKQSILYPXOB-QDLLFRBVSA-N	242587	(2S)-2-(methylamino)-N-(1-((2- methylnaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)propanamide::US10053431, 116	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242587&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077103	376221382							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489344	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC(C)C)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C30H35BrN4O4/c1-18(2)14-28(36)34-17-24(33-29(37)19(3)32-4)30(38)35(26-9-7-6-8-25(26)34)16-23-22-12-11-21(31)15-20(22)10-13-27(23)39-5/h6-13,15,18-19,24,32H,14,16-17H2,1-5H3,(H,33,37)/t19-,24-/m0/s1	RBYCERGIKPUFHO-CYFREDJKSA-N	50441823	CHEMBL2436329::US10053431, 26	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441823&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711029	175454140		CHEMBL2436329				ZINC96285530	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489346	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccc(N)cc1	InChI=1S/C31H33N5O4S/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-35-28-10-6-7-11-29(28)36(41(39,40)24-16-14-23(32)15-17-24)19-27(31(35)38)34-30(37)21(2)33-3/h4-17,21,27,33H,18-19,32H2,1-3H3,(H,34,37)/t21-,27-/m0/s1	DWRWKRQFTZPNIE-IDISGSTGSA-N	242589	(25)-N-[(35)-1-(4-aminophenyl)sulfonyl- 5-[(2-methylnaphthalen-1-yl)methyl]-4- oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]- 2- (methylamino)propanamide;hydrochloride::US10053431, 117	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242589&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531396	376221384							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489348	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCC(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C31H35BrN4O5/c1-19(37)8-7-11-29(38)35-18-25(34-30(39)20(2)33-3)31(40)36(27-10-6-5-9-26(27)35)17-24-23-14-13-22(32)16-21(23)12-15-28(24)41-4/h5-6,9-10,12-16,20,25,33H,7-8,11,17-18H2,1-4H3,(H,34,39)/t20-,25-/m0/s1	ASFSQLSTKRLNRZ-CPJSRVTESA-N	242590	(S)—N—((S)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-5-(5-oxohexanoyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 27	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242590&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076976	376221385							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489350	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(c2)C(C)O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H36N4O4/c1-21-16-17-24-10-5-6-13-27(24)28(21)19-37-30-14-7-8-15-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)26-12-9-11-25(18-26)23(3)39/h5-18,22-23,29,35,39H,19-20H2,1-4H3,(H,36,40)/t22-,23?,29-/m0/s1	HPCMPJMRVFYGCF-PIZRKSBESA-N	242591	(2S)-N-[(3S)-1-[3-(1- hydroxyethyl)benzoyl]-5-[(2- methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;hydrochloride::US10053431, 118::US10053431, 119	E3 ubiquitin-protein ligase XIAP [241-356]			 23690					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242591&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531387	376221386							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489352	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(=O)OC)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H33BrN4O6/c1-20(36-2)31(40)37-27-19-39(32(41)21-9-11-22(12-10-21)34(43)45-4)29-8-6-5-7-28(29)38(33(27)42)18-26-25-15-14-24(35)17-23(25)13-16-30(26)44-3/h5-17,20,27,36H,18-19H2,1-4H3,(H,37,40)/t20-,27-/m0/s1	SXOWGVPZRLSEAF-DCFHFQCYSA-N	242592	4-[(S)-5-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-3-((S)-2-methylamino-propionylamino)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-benzoic acid methyl ester hydrochloride::US10053431, 28	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242592&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077071	376221387							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489354	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(c2)C(C)O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H36N4O4/c1-21-16-17-24-10-5-6-13-27(24)28(21)19-37-30-14-7-8-15-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)26-12-9-11-25(18-26)23(3)39/h5-18,22-23,29,35,39H,19-20H2,1-4H3,(H,36,40)/t22-,23?,29-/m0/s1	HPCMPJMRVFYGCF-PIZRKSBESA-N	242591	(2S)-N-[(3S)-1-[3-(1- hydroxyethyl)benzoyl]-5-[(2- methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;hydrochloride::US10053431, 118::US10053431, 119	E3 ubiquitin-protein ligase XIAP [241-356]			 21710					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242591&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531387	376221386							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489356	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H31BrN4O6/c1-19(35-2)30(39)36-26-18-38(31(40)20-8-10-21(11-9-20)33(42)43)28-7-5-4-6-27(28)37(32(26)41)17-25-24-14-13-23(34)16-22(24)12-15-29(25)44-3/h4-16,19,26,35H,17-18H2,1-3H3,(H,36,39)(H,42,43)/t19-,26-/m0/s1	KICGBGWJSBMWAK-SIBVEZHUSA-N	242594	4-[(S)-5-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-3-((S)-2-methylamino-propionylamino)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-benzoic acid hydrochloride::US10053431, 29	E3 ubiquitin-protein ligase XIAP [241-356]			 51375					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242594&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076882	376221388							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489358	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O	InChI=1S/C37H33N7O4/c1-23(39-3)35(46)40-30-22-42(36(47)26-18-16-25(17-19-26)24(2)45)33-14-8-9-15-34(33)43(37(30)48)21-29-28-11-5-7-13-32(28)44(41-29)31-12-6-4-10-27(31)20-38/h4-19,23,30,39H,21-22H2,1-3H3,(H,40,46)/t23-,30-/m0/s1	IBHPLEGIMMIZAQ-JHOBJCJYSA-N	242595	(S)-N-((S)-5-(4-acetylbenzoyl)-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide 2,2,2- trifluoroacetate::US10053431, 120	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242595&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076802	376221389							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489360	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(N)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H32BrN5O5/c1-19(36-2)31(41)37-26-18-39(32(42)21-10-8-20(9-11-21)30(35)40)28-7-5-4-6-27(28)38(33(26)43)17-25-24-14-13-23(34)16-22(24)12-15-29(25)44-3/h4-16,19,26,36H,17-18H2,1-3H3,(H2,35,40)(H,37,41)/t19-,26-/m0/s1	JFONEQSYAHTTGI-SIBVEZHUSA-N	242596	4-[(S)-5-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-3-((S)-2-methylamino-propionylamino)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-benzamide hydrochloride::US10053431, 30	E3 ubiquitin-protein ligase XIAP [241-356]			 52745					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242596&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076833	376221390							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489362	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2cc(Cl)ccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H32ClN5O3/c1-19-8-9-21-6-4-5-7-25(21)26(19)17-37-28-15-12-23(33)16-29(28)38(31(40)22-10-13-24(34)14-11-22)18-27(32(37)41)36-30(39)20(2)35-3/h4-16,20,27,35H,17-18,34H2,1-3H3,(H,36,39)/t20-,27-/m0/s1	NYASEDZUZJHFTL-DCFHFQCYSA-N	242597	(S)-N-((S)-5-(4-aminobenzoyl)-7-chloro- 1-((2-methylnaphthalen-1-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 121	E3 ubiquitin-protein ligase XIAP [241-356]			 46420					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242597&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077128	376221391							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489364	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(=O)NCC2CCCCC2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C40H44BrN5O5/c1-25(42-2)37(47)44-33-24-46(39(49)28-15-13-27(14-16-28)38(48)43-22-26-9-5-4-6-10-26)35-12-8-7-11-34(35)45(40(33)50)23-32-31-19-18-30(41)21-29(31)17-20-36(32)51-3/h7-8,11-21,25-26,33,42H,4-6,9-10,22-24H2,1-3H3,(H,43,48)(H,44,47)/t25-,33-/m0/s1	OQSLFGBQSWACBU-JQJBXXCASA-N	242598	4-[(S)-5-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-3-((S)-2-methylamino-propionylamino)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-N-cyclohexylmethyl-benzamide hydrochloride::US10053431, 31	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242598&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076651	376221392							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489366	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2cc(Cl)ccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C32H32ClN5O4/c1-19(35-2)30(39)36-26-18-38(31(40)21-8-12-23(34)13-9-21)28-16-22(33)11-14-27(28)37(32(26)41)17-25-24-7-5-4-6-20(24)10-15-29(25)42-3/h4-16,19,26,35H,17-18,34H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	PYGGARGXJMZFPP-SIBVEZHUSA-N	242599	(S)-N-((S)-5-(4-aminobenzoyl)-7-chloro- 1-((2-methoxynaphthalen-1-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 122	E3 ubiquitin-protein ligase XIAP [241-356]			 26390					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242599&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077160	376221393							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489368	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(O)C(F)(F)F)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H32BrF3N4O5/c1-19(39-2)31(44)40-26-18-42(32(45)21-10-8-20(9-11-21)30(43)34(36,37)38)28-7-5-4-6-27(28)41(33(26)46)17-25-24-14-13-23(35)16-22(24)12-15-29(25)47-3/h4-16,19,26,30,39,43H,17-18H2,1-3H3,(H,40,44)/t19-,26-,30?/m0/s1	HLVZIUNUMSNQFS-SIPNUGOWSA-N	242600	(S)—N—{(S)-1-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-2-oxo-5-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-benzoyl]-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl}-2-methylamino-propionamide hydrochloride, mixture of diastereomers::US10053431, 32	E3 ubiquitin-protein ligase XIAP [241-356]			 41535					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242600&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077232	376221394							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489370	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2cc(Cl)ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C32H31BrClN5O4/c1-18(36-2)30(40)37-26-17-39(31(41)19-7-10-21(35)11-8-19)28-15-20(34)9-13-27(28)38(32(26)42)16-24-22-5-4-6-25(33)23(22)12-14-29(24)43-3/h4-15,18,26,36H,16-17,35H2,1-3H3,(H,37,40)/t18-,26-/m0/s1	ZPWXNJPAHZEINN-QYBDOPJKSA-N	242601	(S)-N-((S)-5-(4-aminobenzoyl)-1-((5- bromo-2-methoxynaphthalen-1- yl)methyl)-7-chloro-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 123	E3 ubiquitin-protein ligase XIAP [241-356]			 18740					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242601&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076744	376221395							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489372	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H35BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20-21,28,36,40H,18-19H2,1-4H3,(H,37,41)/t20-,21?,28-/m0/s1	LNZZPMFSHPPZAH-ZWCJHOFGSA-N	241607	(2S)-N-((3S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(4-(1- hydroxyethyl)benzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::BDBM242602::US10053431, 103::US10053431, 104	E3 ubiquitin-protein ligase XIAP [241-356]			 34380					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=241607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=241607&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076904	376221357							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489374	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2cc(Cl)ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H31BrClN5O4/c1-18(36-2)30(40)37-26-17-39(31(41)19-4-9-23(35)10-5-19)28-15-22(34)8-12-27(28)38(32(26)42)16-25-24-11-7-21(33)14-20(24)6-13-29(25)43-3/h4-15,18,26,36H,16-17,35H2,1-3H3,(H,37,40)/t18-,26-/m0/s1	AIUSSHJTBFDDBV-QYBDOPJKSA-N	242603	(S)-N-((S)-5-(4-aminobenzoyl)-1-((6- bromo-2-methoxynaphthalen-1- yl)methyl)-7-chloro-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 124	E3 ubiquitin-protein ligase XIAP [241-356]			 13110					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242603&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076808	376221397							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489376	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C23CC4CC(CC(C4)C2)C3)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C36H41BrN4O4/c1-21(38-2)33(42)39-29-20-41(35(44)36-16-22-12-23(17-36)14-24(13-22)18-36)31-7-5-4-6-30(31)40(34(29)43)19-28-27-10-9-26(37)15-25(27)8-11-32(28)45-3/h4-11,15,21-24,29,38H,12-14,16-20H2,1-3H3,(H,39,42)/t21-,22?,23?,24?,29-,36?/m0/s1	ZYJSAXCVKITGMK-USPVGKNKSA-N	242604	(S)—N—[(S)-5-(Adamantane-1-carbonyl)-1-(6-bromo-2-methoxy-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 34	E3 ubiquitin-protein ligase XIAP [241-356]			 15890					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242604&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076695	376221398							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489378	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2cc(Cl)ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C34H32BrClN4O5/c1-19(37-3)32(42)38-28-18-40(33(43)22-10-8-21(9-11-22)20(2)41)30-16-23(36)12-14-29(30)39(34(28)44)17-26-24-6-5-7-27(35)25(24)13-15-31(26)45-4/h5-16,19,28,37H,17-18H2,1-4H3,(H,38,42)/t19-,28-/m0/s1	DUHMRKGHRWGINZ-VKGTZQKMSA-N	242605	(S)-N-((S)-5-(4-acetylbenzoyl)-1-((5- bromo-2-methoxynaphthalen-1- yl)methyl)-7-chloro-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 125	E3 ubiquitin-protein ligase XIAP [241-356]			 25600					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242605&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077113	376221399							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489380	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H32BrN5O4/c1-19(35-2)30(39)36-26-18-38(31(40)20-8-12-23(34)13-9-20)28-7-5-4-6-27(28)37(32(26)41)17-25-24-14-11-22(33)16-21(24)10-15-29(25)42-3/h4-16,19,26,35H,17-18,34H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	BSUCDFNUQCWZFS-SIBVEZHUSA-N	242606	(S)—N—((S)-5-(4-aminobenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide dihydrochloride::US10053431, 35	E3 ubiquitin-protein ligase XIAP [241-356]			 22090					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242606&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076969	376221400							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489382	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C32H29BrClFN4O4/c1-18(36-2)30(40)37-26-17-39(31(41)19-7-10-21(35)11-8-19)28-15-20(34)9-13-27(28)38(32(26)42)16-24-22-5-4-6-25(33)23(22)12-14-29(24)43-3/h4-15,18,26,36H,16-17H2,1-3H3,(H,37,40)/t18-,26-/m0/s1	ASXCUXYHAICPGC-QYBDOPJKSA-N	242607	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- chloro-5-(4-fluorobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 126	E3 ubiquitin-protein ligase XIAP [241-356]			 21480					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242607&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076835	376221401							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489384	COc1ccc2cc(Br)ccc2c1CN1c2ccccc2N(C[C@H](NC(=O)[C@@H]2CCN2)C1=O)C(=O)c1ccc(cc1)C(C)=O	InChI=1S/C34H31BrN4O5/c1-20(40)21-7-9-22(10-8-21)33(42)39-19-28(37-32(41)27-15-16-36-27)34(43)38(29-5-3-4-6-30(29)39)18-26-25-13-12-24(35)17-23(25)11-14-31(26)44-2/h3-14,17,27-28,36H,15-16,18-19H2,1-2H3,(H,37,41)/t27-,28-/m0/s1	FYPLXCGGIXAPHV-NSOVKSMOSA-N	242608	(S)—N—((S)-5-(4-acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)azetidine-2-carboxamide hydrochloride::US10053431, 36	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242608&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077434	376221402							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489386	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(Cl)ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C33H29BrClN5O4/c1-19(37-2)31(41)38-27-18-40(32(42)21-9-7-20(16-36)8-10-21)29-15-22(35)11-13-28(29)39(33(27)43)17-25-23-5-4-6-26(34)24(23)12-14-30(25)44-3/h4-15,19,27,37H,17-18H2,1-3H3,(H,38,41)/t19-,27-/m0/s1	FXUKLVOPWTYLHG-PPHZAIPVSA-N	242609	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- chloro-5-(4-cyanobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 127	E3 ubiquitin-protein ligase XIAP [241-356]			 26730					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242609&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077364	376221403							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489388	CN[C@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28+/m1/s1	VBKYKJZFJATBDB-NGOKVRLYSA-N	242610	(R)—N—((S)-5-(4-acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 37	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242610&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076991	376221404							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489390	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C31H29BrN4O4/c1-19(33-2)29(37)34-28-30(38)35(18-24-23-15-14-21(32)17-20(23)13-16-27(24)40-3)25-11-7-8-12-26(25)36(31(28)39)22-9-5-4-6-10-22/h4-17,19,28,33H,18H2,1-3H3,(H,34,37)/t19-,28?/m0/s1	YVTYAMQGTKOVBC-ZAFBDEJNSA-N	242611	(2S)-N-(1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 128	E3 ubiquitin-protein ligase XIAP [241-356]			 44820					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242611&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			91758773	376221405							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489392	COc1ccc2cc(Br)ccc2c1CN1c2ccccc2N(C[C@H](NC(=O)[C@H](C)N(C)C)C1=O)C(=O)c1ccc(cc1)C(C)=O	InChI=1S/C35H35BrN4O5/c1-21(38(3)4)33(42)37-29-20-40(34(43)24-12-10-23(11-13-24)22(2)41)31-9-7-6-8-30(31)39(35(29)44)19-28-27-16-15-26(36)18-25(27)14-17-32(28)45-5/h6-18,21,29H,19-20H2,1-5H3,(H,37,42)/t21-,29-/m0/s1	HMSRUTJNXZGPKD-LGGPFLRQSA-N	242612	(S)—N—((S)-5-(4-acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(dimethylamino)propanamide::US10053431, 38	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242612&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076730	376221406							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489394	CN[C@@H](C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C31H29BrN4O4/c1-19(33-2)29(37)34-28-30(38)35(18-23-21-12-9-13-24(32)22(21)16-17-27(23)40-3)25-14-7-8-15-26(25)36(31(28)39)20-10-5-4-6-11-20/h4-17,19,28,33H,18H2,1-3H3,(H,34,37)/t19-,28?/m0/s1	DEKPQKVLGOFSJI-ZAFBDEJNSA-N	242613	(2S)-N-(1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 129	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242613&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531397	376221407							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489396	COc1ccc2cc(Br)ccc2c1CN1c2ccccc2N(C[C@H](NC(=O)[C@H](C)N)C1=O)C(=O)c1ccc(cc1)C(C)=O	InChI=1S/C33H31BrN4O5/c1-19(35)31(40)36-27-18-38(32(41)22-10-8-21(9-11-22)20(2)39)29-7-5-4-6-28(29)37(33(27)42)17-26-25-14-13-24(34)16-23(25)12-15-30(26)43-3/h4-16,19,27H,17-18,35H2,1-3H3,(H,36,40)/t19-,27-/m0/s1	PSNQIUPKZKGASK-PPHZAIPVSA-N	242614	(S)—N—((S)-5-(4-acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-aminopropanamide hydrochloride::US10053431, 39	E3 ubiquitin-protein ligase XIAP [241-356]			 31930					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242614&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076637	376221408					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489398	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H29BrClFN4O4/c1-18(36-2)30(40)37-26-17-39(31(41)19-4-9-23(35)10-5-19)28-15-22(34)8-12-27(28)38(32(26)42)16-25-24-11-7-21(33)14-20(24)6-13-29(25)43-3/h4-15,18,26,36H,16-17H2,1-3H3,(H,37,40)/t18-,26-/m0/s1	FDPZDJGLHIXCAI-QYBDOPJKSA-N	242615	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-7- chloro-5-(4-fluorobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 130	E3 ubiquitin-protein ligase XIAP [241-356]			 16430					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242615&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076793	376221409							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489400	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(CCc2cccc3ccccc23)C1=O	InChI=1S/C34H34N4O4/c1-22(35-3)32(40)36-29-21-38(33(41)27-17-15-24(16-18-27)23(2)39)31-14-7-6-13-30(31)37(34(29)42)20-19-26-11-8-10-25-9-4-5-12-28(25)26/h4-18,22,29,35H,19-21H2,1-3H3,(H,36,40)/t22-,29-/m0/s1	NVXMSTOAPJLPRH-ZTOMLWHTSA-N	242616	(S)—N—((S)-5-(4-acetylbenzoyl)-1-(2-(naphthalen-1-yl)ethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide::US10053431, 40	E3 ubiquitin-protein ligase XIAP [241-356]			 7423					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242616&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086253	376221410							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489402	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(Cl)ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H29BrClN5O4/c1-19(37-2)31(41)38-27-18-40(32(42)21-6-4-20(16-36)5-7-21)29-15-24(35)10-12-28(29)39(33(27)43)17-26-25-11-9-23(34)14-22(25)8-13-30(26)44-3/h4-15,19,27,37H,17-18H2,1-3H3,(H,38,41)/t19-,27-/m0/s1	ATANOOYHOJRMCH-PPHZAIPVSA-N	242617	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-7- chloro-5-(4-cyanobenzoyl)-2-oxo-2,3 tetrahydro-1H-benzo[b][1,4]diazepin- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 131	E3 ubiquitin-protein ligase XIAP [241-356]			 29830					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242617&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077330	376221411							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489404	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O4/c1-20(34-2)30(38)35-26-19-37(31(39)22-12-15-23(33)16-13-22)28-11-7-6-10-27(28)36(32(26)40)18-25-24-9-5-4-8-21(24)14-17-29(25)41-3/h4-17,20,26,34H,18-19,33H2,1-3H3,(H,35,38)/t20-,26-/m0/s1	BXNIMYHZUMCTGM-FNZWTVRRSA-N	50441816	CHEMBL2436208::US10053431, 41	E3 ubiquitin-protein ligase XIAP [241-356]			 24520					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441816&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	1RH	4KJU	71819719	175454133		CHEMBL2436208				ZINC96285524	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489406	CCN[C@@H](CC)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C33H33BrN4O4/c1-4-26(35-5-2)31(39)36-30-32(40)37(20-25-24-17-16-22(34)19-21(24)15-18-29(25)42-3)27-13-9-10-14-28(27)38(33(30)41)23-11-7-6-8-12-23/h6-19,26,30,35H,4-5,20H2,1-3H3,(H,36,39)/t26-,30?/m0/s1	HWIHWDMCQSBKGA-PKMDPOOCSA-N	242619	(2S)-N-(1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][l,4]diazepin-3-yl)-2- (ethylamino)butanamide::US10053431, 132	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242619&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531385	376221413							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489408	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(NC(C)=O)cc2)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C34H35N5O5/c1-21(35-3)32(41)37-28-20-39(33(42)24-13-16-25(17-14-24)36-22(2)40)30-12-8-7-11-29(30)38(34(28)43)19-27-26-10-6-5-9-23(26)15-18-31(27)44-4/h5-18,21,28,35H,19-20H2,1-4H3,(H,36,40)(H,37,41)/t21-,28-/m0/s1	ZZMWAGXEJSTILS-KMRXNPHXSA-N	242620	(S)—N—[(S)-5-(4-Acetylamino-benzoyl)-1-(2-methoxy-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 42	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242620&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077080	376221414							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489410	CC[C@H](N)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C31H29BrN4O4/c1-3-24(33)29(37)34-28-30(38)35(18-23-22-15-14-20(32)17-19(22)13-16-27(23)40-2)25-11-7-8-12-26(25)36(31(28)39)21-9-5-4-6-10-21/h4-17,24,28H,3,18,33H2,1-2H3,(H,34,37)/t24-,28?/m0/s1	YXJMOPISMTUTLI-ZZDYIDRTSA-N	242621	(2S)-2-amino-N-(1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)butanamide::US10053431, 133	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242621&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076821	376221415							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489412	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C36H36N4O7/c1-21(37-3)33(42)38-29-20-40(34(43)24-12-10-23(11-13-24)22(2)41)31-9-7-6-8-30(31)39(35(29)44)19-28-27-16-14-26(36(45)47-5)18-25(27)15-17-32(28)46-4/h6-18,21,29,37H,19-20H2,1-5H3,(H,38,42)/t21-,29-/m0/s1	NCWHDTFFARAZAY-LGGPFLRQSA-N	242622	5-[(S)-5-(4-Acetyl-benzoyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalen-2-carboxylic acid methyl ester hydrochloride::US10053431, 43	E3 ubiquitin-protein ligase XIAP [241-356]			 44080					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242622&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077397	376221416							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489414	CCN[C@@H](CC)C(=O)NC1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C33H33BrN4O4/c1-4-26(35-5-2)31(39)36-30-32(40)37(20-24-22-14-11-15-25(34)23(22)18-19-29(24)42-3)27-16-9-10-17-28(27)38(33(30)41)21-12-7-6-8-13-21/h6-19,26,30,35H,4-5,20H2,1-3H3,(H,36,39)/t26-,30?/m0/s1	MIIIBECDVPUFSN-PKMDPOOCSA-N	242623	(2S)-N-(1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (ethylamino)butanamide::US10053431, 134	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242623&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531487	376221417							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489416	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C35H34N4O7/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-13-25(35(44)45)17-24(26)14-16-31(27)46-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)(H,44,45)/t20-,28-/m0/s1	FVTPBOSWDFCXGN-MMTVBGGISA-N	242624	5-[[(3S)-1-(4-acetylbenzoyl)-3-[[(2S)-2-(methylamino)propanoyl]amino]-4-oxo-2,3-dihydro-1,5-benzodiazepin-5-yl]methyl]-6-methoxy-naphthalene-2-carboxylic acid; hydrochloride::US10053431, 44	E3 ubiquitin-protein ligase XIAP [241-356]			 17365					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242624&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077153	376221418							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489418	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(Cl)ccc2N(Cc2c(OCC(F)(F)F)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H28BrClF3N5O4/c1-19(41-2)31(45)42-27-17-44(32(46)21-5-3-20(15-40)4-6-21)29-14-24(36)9-11-28(29)43(33(27)47)16-26-25-10-8-23(35)13-22(25)7-12-30(26)48-18-34(37,38)39/h3-14,19,27,41H,16-18H2,1-2H3,(H,42,45)/t19-,27-/m0/s1	DOUYUMOASBGOAP-PPHZAIPVSA-N	242625	(S)-N-((S)-1-((6-bromo-2-(2,2,2- trifluoroethoxy)naphthalen-1-yl)methyl)- 7-chloro-5-(4-cyanobenzoyl)-2-oxo- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 135	E3 ubiquitin-protein ligase XIAP [241-356]			 36210					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242625&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076708	376221419							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489420	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)NO)C1=O	InChI=1S/C35H35N5O7/c1-20(36-3)32(42)37-28-19-40(34(44)23-11-9-22(10-12-23)21(2)41)30-8-6-5-7-29(30)39(35(28)45)18-27-26-15-13-25(33(43)38-46)17-24(26)14-16-31(27)47-4/h5-17,20,28,36,46H,18-19H2,1-4H3,(H,37,42)(H,38,43)/t20-,28-/m0/s1	XAHVSYGGAZYANK-MMTVBGGISA-N	242626	5-(((S)-5-(4-acetylbenzoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-N-hydroxy-6-methoxy-2-naphthamide 2,2,2-trifluoroacetate::US10053431, 45	E3 ubiquitin-protein ligase XIAP [241-356]			 29915					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242626&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086579	376221420							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489422	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2c(OCC(F)(F)F)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H28BrClF4N4O4/c1-18(40-2)30(44)41-26-16-43(31(45)19-3-8-23(36)9-4-19)28-14-22(35)7-11-27(28)42(32(26)46)15-25-24-10-6-21(34)13-20(24)5-12-29(25)47-17-33(37,38)39/h3-14,18,26,40H,15-17H2,1-2H3,(H,41,44)/t18-,26-/m0/s1	OWKXLFXHVOCRPK-QYBDOPJKSA-N	242627	(S)-N-((S)-1-((6-bromo-2-(2,2,2- trifluoroethoxy)naphthalen-1-yl)methyl)- 7-chloro-5-(4-fluorobenzoyl)-2-oxo- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 136	E3 ubiquitin-protein ligase XIAP [241-356]			 41900					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242627&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531379	376221421							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489424	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCC(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C33H38N4O7/c1-20(38)9-8-12-30(39)36-19-26(35-31(40)21(2)34-3)32(41)37(28-11-7-6-10-27(28)36)18-25-24-15-13-23(33(42)44-5)17-22(24)14-16-29(25)43-4/h6-7,10-11,13-17,21,26,34H,8-9,12,18-19H2,1-5H3,(H,35,40)/t21-,26-/m0/s1	KEAUHXQFUGWZRT-LVXARBLLSA-N	242628	6-Methoxy-5-[(S)-3 ((S)-2-methylamino-propionylamino)-2-oxo-5-(5-oxo-hexanoyl)-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 46	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242628&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077201	376221422							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489426	CC[C@H](N)C(=O)NC1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C31H29BrN4O4/c1-3-24(33)29(37)34-28-30(38)35(18-22-20-12-9-13-23(32)21(20)16-17-27(22)40-2)25-14-7-8-15-26(25)36(31(28)39)19-10-5-4-6-11-19/h4-17,24,28H,3,18,33H2,1-2H3,(H,34,37)/t24-,28?/m0/s1	FDGYZDRJWNTPHP-ZZDYIDRTSA-N	242629	(2S)-2-amino-N-(1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)butanamide::US10053431, 137	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242629&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076741	376221423							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489428	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCC(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C32H36N4O7/c1-19(37)8-7-11-29(38)35-18-25(34-30(39)20(2)33-3)31(40)36(27-10-6-5-9-26(27)35)17-24-23-14-12-22(32(41)42)16-21(23)13-15-28(24)43-4/h5-6,9-10,12-16,20,25,33H,7-8,11,17-18H2,1-4H3,(H,34,39)(H,41,42)/t20-,25-/m0/s1	FXMDDPAOFCIITP-CPJSRVTESA-N	242630	6-Methoxy-5-[(S)-3 ((S)-2-methylamino-propionylamino)-2-oxo-5-(5-oxo-hexanoyl)-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-naphthalene-2-carboxylic acid hydrochloride::US10053431, 47	E3 ubiquitin-protein ligase XIAP [241-356]			 44645					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242630&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077206	376221424							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489430	CC[C@H](NCCO)C(=O)NC1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccccc2N(c2ccccc2)C1=O	InChI=1S/C33H33BrN4O5/c1-3-26(35-18-19-39)31(40)36-30-32(41)37(20-24-22-12-9-13-25(34)23(22)16-17-29(24)43-2)27-14-7-8-15-28(27)38(33(30)42)21-10-5-4-6-11-21/h4-17,26,30,35,39H,3,18-20H2,1-2H3,(H,36,40)/t26-,30?/m0/s1	CJJFBBNABFDOPN-PKMDPOOCSA-N	242631	(2S)-N-(1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2-(2- hydroxyethylamino)butanamide::US10053431, 138	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242631&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531372	376221425							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489432	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCNC(=O)OCC2c3ccccc3-c3ccccc23)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C46H47N5O8/c1-28(47-2)43(53)49-38-26-50(42(52)18-11-23-48-46(56)59-27-37-34-14-7-5-12-32(34)33-13-6-8-15-35(33)37)39-16-9-10-17-40(39)51(44(38)54)25-36-31-21-19-30(45(55)58-4)24-29(31)20-22-41(36)57-3/h5-10,12-17,19-22,24,28,37-38,47H,11,18,23,25-27H2,1-4H3,(H,48,56)(H,49,53)/t28-,38-/m0/s1	QIROBYRCQIRCNB-SNFDCCKOSA-N	242632	5-[(S)-5-[4-(9H-Fluoren-9-ylmethoxycarbonylamino)-butyryl]-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 48	E3 ubiquitin-protein ligase XIAP [241-356]			 33160					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242632&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077286	376221426							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489434	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(Cl)ccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C33H28ClF2N5O4/c1-19(38-2)30(42)39-26-18-41(31(43)22-9-7-20(16-37)8-10-22)28-15-23(34)12-13-27(28)40(32(26)44)17-25-24-6-4-3-5-21(24)11-14-29(25)45-33(35)36/h3-15,19,26,33,38H,17-18H2,1-2H3,(H,39,42)/t19-,26-/m0/s1	SXXGANNPODJWEW-SIBVEZHUSA-N	242633	(S)-N-((S)-7-chloro-5-(4-cyanobenzoyl)- 1-((2-(difluoromethoxy)naphthalen-1- yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 139	E3 ubiquitin-protein ligase XIAP [241-356]			 36900					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242633&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076609	376221427							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489436	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C31H37N5O6/c1-19(33-2)29(38)34-24-18-35(28(37)10-7-15-32)25-8-5-6-9-26(25)36(30(24)39)17-23-22-13-11-21(31(40)42-4)16-20(22)12-14-27(23)41-3/h5-6,8-9,11-14,16,19,24,33H,7,10,15,17-18,32H2,1-4H3,(H,34,38)/t19-,24-/m0/s1	OOCGOLCPNAMEDL-CYFREDJKSA-N	242634	5-[(S)-5-(4-Amino-butyryl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 49	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242634&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076919	376221428							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489438	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C32H28ClF3N4O4/c1-18(37-2)29(41)38-25-17-40(30(42)20-7-11-22(34)12-8-20)27-15-21(33)10-13-26(27)39(31(25)43)16-24-23-6-4-3-5-19(23)9-14-28(24)44-32(35)36/h3-15,18,25,32,37H,16-17H2,1-2H3,(H,38,41)/t18-,25-/m0/s1	PYMRZTOFARKIFX-BVZFJXPGSA-N	242635	(S)-N-((S)-7-chloro-1-((2- (difluoromethoxy)naphthalen-1- yl)methyl)-5-(4-fluorobenzoyl)-2-oxo- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 140	E3 ubiquitin-protein ligase XIAP [241-356]			 48750					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242635&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076831	376221429							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489440	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C30H35N5O6/c1-18(32-2)28(37)33-23-17-34(27(36)9-6-14-31)24-7-4-5-8-25(24)35(29(23)38)16-22-21-12-10-20(30(39)40)15-19(21)11-13-26(22)41-3/h4-5,7-8,10-13,15,18,23,32H,6,9,14,16-17,31H2,1-3H3,(H,33,37)(H,39,40)/t18-,23-/m0/s1	CDLJEUGALIIVIE-MBSDFSHPSA-N	242636	5-(((S)-5-(4-aminobutanoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-6-methoxy-2-naphthoic acid hydrochloride::US10053431, 50	E3 ubiquitin-protein ligase XIAP [241-356]			 18510					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242636&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077102	376221430							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489442	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc3[nH]ncc3c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242637	(25)-N-[(3S)-1-(1H-indazole-5-carbonyl)- 5-[(2-methylnaphthalen-1-yl)methyl]-4- oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]- 2-(methylamino)propanamide::US10053431, 141	E3 ubiquitin-protein ligase XIAP [241-356]			 48270					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242637&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531430	376221431							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489444	CN[C@@H](C)C(=O)N[C@H]1CN2c3ccccc3N(Cc3c(OC)ccc4cc(ccc34)C(=O)NCCCC2=O)C1=O	InChI=1S/C30H33N5O5/c1-18(31-2)28(37)33-23-17-34-24-7-4-5-8-25(24)35(30(23)39)16-22-21-12-10-20(15-19(21)11-13-26(22)40-3)29(38)32-14-6-9-27(34)36/h4-5,7-8,10-13,15,18,23,31H,6,9,14,16-17H2,1-3H3,(H,32,38)(H,33,37)/t18-,23-/m0/s1	CAPNFUSCYNKMBU-MBSDFSHPSA-N	242638	Cyclic-5-[(S)-5-(4-Amino-butyryl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 51	E3 ubiquitin-protein ligase XIAP [241-356]			 42800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242638&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552253	376221432							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489446	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(ccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O)C#N	InChI=1S/C34H28F2N6O4/c1-20(39-2)31(43)40-27-19-42(32(44)24-10-7-21(16-37)8-11-24)29-15-22(17-38)9-13-28(29)41(33(27)45)18-26-25-6-4-3-5-23(25)12-14-30(26)46-34(35)36/h3-15,20,27,34,39H,18-19H2,1-2H3,(H,40,43)/t20-,27-/m0/s1	NUQCTFCSNHXABS-DCFHFQCYSA-N	242639	(S)-N-((S)-7-cyano-5-(4-cyanobenzoyl)- 1-((2-(difluoromethoxy)naphthalen-1- yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 142	E3 ubiquitin-protein ligase XIAP [241-356]			 47230					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242639&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077274	376221433							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489448	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C32H39N5O6/c1-20(34-2)30(39)35-25-19-36(29(38)11-7-8-16-33)26-9-5-6-10-27(26)37(31(25)40)18-24-23-14-12-22(32(41)43-4)17-21(23)13-15-28(24)42-3/h5-6,9-10,12-15,17,20,25,34H,7-8,11,16,18-19,33H2,1-4H3,(H,35,39)/t20-,25-/m0/s1	ITLOVOGSDIIYGZ-CPJSRVTESA-N	242640	5-[(S)-5-(5-amino-pentanoyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 52	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242640&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077294	376221434							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489450	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O)C#N	InChI=1S/C34H29BrN6O4/c1-20(38-2)32(42)39-28-19-41(33(43)23-10-7-21(16-36)8-11-23)30-15-22(17-37)9-13-29(30)40(34(28)44)18-26-24-5-4-6-27(35)25(24)12-14-31(26)45-3/h4-15,20,28,38H,18-19H2,1-3H3,(H,39,42)/t20-,28-/m0/s1	ZFAYVSVZTBMEQS-MMTVBGGISA-N	242641	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-5-(4-cyanobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 143	E3 ubiquitin-protein ligase XIAP [241-356]			 16260					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242641&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076866	376221435							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489452	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C31H37N5O6/c1-19(33-2)29(38)34-24-18-35(28(37)10-6-7-15-32)25-8-4-5-9-26(25)36(30(24)39)17-23-22-13-11-21(31(40)41)16-20(22)12-14-27(23)42-3/h4-5,8-9,11-14,16,19,24,33H,6-7,10,15,17-18,32H2,1-3H3,(H,34,38)(H,40,41)/t19-,24-/m0/s1	ZEQVZXSLPYMCCP-CYFREDJKSA-N	242642	5-(((S)-5-(5-aminopentanoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-6-methoxy-2-naphthoic acid hydrochloride::US10053431, 53	E3 ubiquitin-protein ligase XIAP [241-356]			 18620					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242642&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077408	376221436							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489454	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2cc(ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O)C#N	InChI=1S/C34H29BrN6O4/c1-20(38-2)32(42)39-28-19-41(33(43)23-7-4-21(16-36)5-8-23)30-14-22(17-37)6-12-29(30)40(34(28)44)18-27-26-11-10-25(35)15-24(26)9-13-31(27)45-3/h4-15,20,28,38H,18-19H2,1-3H3,(H,39,42)/t20-,28-/m0/s1	AZHWCQYLXCWUJT-MMTVBGGISA-N	242643	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-5-(4-cyanobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 144	E3 ubiquitin-protein ligase XIAP [241-356]			 23760					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242643&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077138	376221437							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489456	CN[C@@H](C)C(=O)N[C@H]1CN2c3ccccc3N(Cc3c(OC)ccc4cc(ccc34)C(=O)NCCCCC2=O)C1=O	InChI=1S/C31H35N5O5/c1-19(32-2)29(38)34-24-18-35-25-8-4-5-9-26(25)36(31(24)40)17-23-22-13-11-21(16-20(22)12-14-27(23)41-3)30(39)33-15-7-6-10-28(35)37/h4-5,8-9,11-14,16,19,24,32H,6-7,10,15,17-18H2,1-3H3,(H,33,39)(H,34,38)/t19-,24-/m0/s1	HJCKKFKEKMJCJL-CYFREDJKSA-N	242644	Cyclic-5-[(S)-5-(5-amino-pentanoyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 54	E3 ubiquitin-protein ligase XIAP [241-356]			 16020					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242644&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086440	376221438							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489458	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc3[nH]ccc3c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242645	(25)-N-[(3S)-1-(1H-indole-5-carbonyl)-5- [(2-methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (melhylamino)propanamide::US10053431, 145	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242645&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531550	376221439							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489460	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(NC(=O)OCC3c4ccccc4-c4ccccc34)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C49H45N5O8/c1-29(50-2)45(55)52-41-27-54(43-16-10-9-15-42(43)53(47(41)57)26-39-34-23-19-32(48(58)61-4)25-31(34)20-24-44(39)60-3)46(56)30-17-21-33(22-18-30)51-49(59)62-28-40-37-13-7-5-11-35(37)36-12-6-8-14-38(36)40/h5-25,29,40-41,50H,26-28H2,1-4H3,(H,51,59)(H,52,55)/t29-,41-/m0/s1	GSYFZEKZPQSPGM-GJPBYDNQSA-N	242646	5-[(S)-5-[4-(9H-Fluoren-9-ylmethoxycarbonylamino)-benzoyl]-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 55	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242646&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077349	376221440							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489462	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc3[nH]ccc23)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242647	(2S)-N-[(3S)-1-(1H-indole-4-carbonyl)-5- [(2-methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide::US10053431, 146	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242647&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531464	376221441							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489464	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C34H35N5O6/c1-20(36-2)31(40)37-27-19-39(32(41)21-9-13-24(35)14-10-21)29-8-6-5-7-28(29)38(33(27)42)18-26-25-15-11-23(34(43)45-4)17-22(25)12-16-30(26)44-3/h5-17,20,27,36H,18-19,35H2,1-4H3,(H,37,40)/t20-,27-/m0/s1	LIVBSIKTRVIQMV-DCFHFQCYSA-N	242648	5-[(S)-5-(4-Amino-benzoyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 56	E3 ubiquitin-protein ligase XIAP [241-356]			 38120					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242648&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076944	376221442							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489466	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc3[nH]ncc23)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242649	(2S)-N-[(3S)-1-(1H-indazole-4-carbonyl)- 5-[(2-methylnaphthalen-1-yl)methyl]-4- oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]- 2-(methylamino)propanamide::US10053431, 147	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242649&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531382	376221443							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489468	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C33H33N5O6/c1-19(35-2)30(39)36-26-18-38(31(40)20-8-12-23(34)13-9-20)28-7-5-4-6-27(28)37(32(26)41)17-25-24-14-10-22(33(42)43)16-21(24)11-15-29(25)44-3/h4-16,19,26,35H,17-18,34H2,1-3H3,(H,36,39)(H,42,43)/t19-,26-/m0/s1	YVMFJSWIPWZQQR-SIBVEZHUSA-N	242650	5-(((S)-5-(4-aminobenzoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-6-methoxy-2-naphthoic acid hydrochloride::US10053431, 57	E3 ubiquitin-protein ligase XIAP [241-356]			 20790					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242650&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076729	376221444							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489470	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2[C@H](C)O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H36N4O4/c1-21-17-18-24-11-5-6-13-26(24)28(21)19-37-30-15-9-10-16-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)27-14-8-7-12-25(27)23(3)39/h5-18,22-23,29,35,39H,19-20H2,1-4H3,(H,36,40)/t22-,23-,29-/m0/s1	TVHGDHABYXJTBR-BOSRLCDASA-N	242651	(2S)-N-[(3S)-1-[2-[(1S)-1- hydroxyethyl]benzoyl]-5-[(2- methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;(2S)-N-[(3S)- 1-[2-[(1R)-1-hydroxyethyl]benzoyl]-5- [(2-methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide::US10053431, 148::US10053431, 153	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242651&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531424	376221445							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489472	CN[C@@H](C)C(=O)N[C@H]1CN2CCCNC(=O)c3ccc4c(CN(c5ccccc25)C1=O)c(OC)ccc4c3	InChI=1S/C29H33N5O4/c1-18(30-2)27(35)32-23-17-33-14-6-13-31-28(36)20-9-11-21-19(15-20)10-12-26(38-3)22(21)16-34(29(23)37)25-8-5-4-7-24(25)33/h4-5,7-12,15,18,23,30H,6,13-14,16-17H2,1-3H3,(H,31,36)(H,32,35)/t18-,23-/m0/s1	ILJSXABYHBJFSO-MBSDFSHPSA-N	242652	Cyclic-5-[(S)-5-(3-amino-propyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 58	E3 ubiquitin-protein ligase XIAP [241-356]			 19000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242652&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086444	376221446							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489474	CCN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C29H33BrN4O6S/c1-5-31-18(2)28(36)32-23-16-33(27(35)17-41(4,38)39)24-8-6-7-9-25(24)34(29(23)37)15-22-21-12-11-20(30)14-19(21)10-13-26(22)40-3/h6-14,18,23,31H,5,15-17H2,1-4H3,(H,32,36)/t18-,23-/m0/s1	PXMMLWALQXHVIQ-MBSDFSHPSA-N	242653	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(ethylamino)propanamide::US10053431, 149	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242653&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077056	376221447							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489476	CN[C@@H](C)C(=O)N[C@H]1CN2CCNC(=O)c3ccc4c(CN(c5ccccc25)C1=O)c(OC)ccc4c3	InChI=1S/C28H31N5O4/c1-17(29-2)26(34)31-22-16-32-13-12-30-27(35)19-8-10-20-18(14-19)9-11-25(37-3)21(20)15-33(28(22)36)24-7-5-4-6-23(24)32/h4-11,14,17,22,29H,12-13,15-16H2,1-3H3,(H,30,35)(H,31,34)/t17-,22-/m0/s1	UXMSPXIBLYEUGT-JTSKRJEESA-N	242654	Cyclic-5-[(S)-5-(2-Amino-ethyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 59	E3 ubiquitin-protein ligase XIAP [241-356]			 31430					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242654&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552394	376221448							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489478	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O)C#N	InChI=1S/C33H29BrFN5O4/c1-19(37-2)31(41)38-27-18-40(32(42)21-8-10-22(35)11-9-21)29-15-20(16-36)7-13-28(29)39(33(27)43)17-25-23-5-4-6-26(34)24(23)12-14-30(25)44-3/h4-15,19,27,37H,17-18H2,1-3H3,(H,38,41)/t19-,27-/m0/s1	SRPYIGHROMQIEO-PPHZAIPVSA-N	242655	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-5-(4-fluorobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 150	E3 ubiquitin-protein ligase XIAP [241-356]			 12330					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242655&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077167	376221449							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489480	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCC(O)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C31H36N4O5/c1-20-16-17-22-10-4-5-11-23(22)24(20)18-35-27-13-7-6-12-26(27)34(28(36)14-8-9-15-29(37)38)19-25(31(35)40)33-30(39)21(2)32-3/h4-7,10-13,16-17,21,25,32H,8-9,14-15,18-19H2,1-3H3,(H,33,39)(H,37,38)/t21-,25-/m0/s1	SLPPHWLGGWMBHJ-OFVILXPXSA-N	242656	6-((S)-3-((S)-2-(methylamino)propanamido)-5-((2-methylnaphthalen-1-yl)methyl)-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)-6-oxohexanoic acid hydrochloride::US10053431, 60	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242656&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076789	376221450							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489482	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(ccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O)C#N	InChI=1S/C33H28F3N5O4/c1-19(38-2)30(42)39-26-18-41(31(43)22-8-11-23(34)12-9-22)28-15-20(16-37)7-13-27(28)40(32(26)44)17-25-24-6-4-3-5-21(24)10-14-29(25)45-33(35)36/h3-15,19,26,33,38H,17-18H2,1-2H3,(H,39,42)/t19-,26-/m0/s1	LKJDLVPHMUIGSF-SIBVEZHUSA-N	242657	(S)-N-((S)-7-cyano-1-((2- (difluoromethoxy)naphthalen-1- yl)methyl)-5-(4-fluorobenzoyl)-2-oxo- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 151	E3 ubiquitin-protein ligase XIAP [241-356]			 48960					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242657&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076785	376221451							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489484	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C30H35N5O6/c1-18(32-2)28(37)33-23-17-34(27(36)13-14-31)24-7-5-6-8-25(24)35(29(23)38)16-22-21-11-9-20(30(39)41-4)15-19(21)10-12-26(22)40-3/h5-12,15,18,23,32H,13-14,16-17,31H2,1-4H3,(H,33,37)/t18-,23-/m0/s1	OMXCQEFOIWXWJB-MBSDFSHPSA-N	242658	5-[(S)-5-(3-Amino-propionyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic acid methyl ester hydrochloride::US10053431, 61	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242658&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076584	376221452							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489486	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc3cc[nH]c3c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242659	(2S)-N-[(3S)-1-(1H-indole-6-carbonyl)-5- [(2-methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide::US10053431, 152	E3 ubiquitin-protein ligase XIAP [241-356]			 51660					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242659&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531471	376221453							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489488	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCN)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(O)=O)C1=O	InChI=1S/C29H33N5O6/c1-17(31-2)27(36)32-22-16-33(26(35)12-13-30)23-6-4-5-7-24(23)34(28(22)37)15-21-20-10-8-19(29(38)39)14-18(20)9-11-25(21)40-3/h4-11,14,17,22,31H,12-13,15-16,30H2,1-3H3,(H,32,36)(H,38,39)/t17-,22-/m0/s1	YUQXREDHCHFNGW-JTSKRJEESA-N	242660	5-(((S)-5-(3-aminopropanoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-6-methoxy-2-naphthoic acid hydrochloride::US10053431, 62	E3 ubiquitin-protein ligase XIAP [241-356]			 41270					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242660&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076687	376221454							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489490	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2[C@H](C)O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H36N4O4/c1-21-17-18-24-11-5-6-13-26(24)28(21)19-37-30-15-9-10-16-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)27-14-8-7-12-25(27)23(3)39/h5-18,22-23,29,35,39H,19-20H2,1-4H3,(H,36,40)/t22-,23-,29-/m0/s1	TVHGDHABYXJTBR-BOSRLCDASA-N	242651	(2S)-N-[(3S)-1-[2-[(1S)-1- hydroxyethyl]benzoyl]-5-[(2- methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;(2S)-N-[(3S)- 1-[2-[(1R)-1-hydroxyethyl]benzoyl]-5- [(2-methylnaphthalen-1-yl)methyl]-4-oxo- 2,3-dihydro-1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide::US10053431, 148::US10053431, 153	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242651&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531424	376221445							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489492	CN[C@@H](C)C(=O)N[C@H]1CN2c3ccccc3N(Cc3c(OC)ccc4cc(ccc34)C(=O)NCCC2=O)C1=O	InChI=1S/C29H31N5O5/c1-17(30-2)27(36)32-22-16-33-23-6-4-5-7-24(23)34(29(22)38)15-21-20-10-8-19(28(37)31-13-12-26(33)35)14-18(20)9-11-25(21)39-3/h4-11,14,17,22,30H,12-13,15-16H2,1-3H3,(H,31,37)(H,32,36)/t17-,22-/m0/s1	RRJQCQZSAWTOKG-JTSKRJEESA-N	242662	Cyclic-5-[(S)-5-(3-Amino-propionyl)-3-((S)-2-methylamino-propionylamino)-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-ylmethyl]-6-methoxy-naphthalene-2-carboxylic amide hydrochloride::US10053431, 63	E3 ubiquitin-protein ligase XIAP [241-356]			 42950					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242662&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552396	376221455							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489494	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(ccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O)C#N	InChI=1S/C33H29BrFN5O4/c1-19(37-2)31(41)38-27-18-40(32(42)21-5-9-24(35)10-6-21)29-14-20(16-36)4-12-28(29)39(33(27)43)17-26-25-11-8-23(34)15-22(25)7-13-30(26)44-3/h4-15,19,27,37H,17-18H2,1-3H3,(H,38,41)/t19-,27-/m0/s1	LSHPLXHILQVMFS-PPHZAIPVSA-N	242663	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-5-(4-fluorobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 154	E3 ubiquitin-protein ligase XIAP [241-356]			 19150					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242663&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077038	376221456							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489496	C[C@H](N)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H32N4O4/c1-20-12-13-24-8-4-5-9-26(24)27(20)18-36-29-10-6-7-11-30(29)37(19-28(33(36)41)35-31(39)21(2)34)32(40)25-16-14-23(15-17-25)22(3)38/h4-17,21,28H,18-19,34H2,1-3H3,(H,35,39)/t21-,28-/m0/s1	HDRZXKUDFVCNST-KMRXNPHXSA-N	242664	(S)—N—((S)-5-(4-acetylbenzoyl)-1-((2-methylnaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-aminopropanamide hydrochloride::US10053431, 64	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242664&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077246	376221457					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489498	CCN[C@@H](CC)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C30H35BrN4O6S/c1-5-23(32-6-2)29(37)33-24-17-34(28(36)18-42(4,39)40)25-12-7-8-13-26(25)35(30(24)38)16-21-19-10-9-11-22(31)20(19)14-15-27(21)41-3/h7-15,23-24,32H,5-6,16-18H2,1-4H3,(H,33,37)/t23-,24-/m0/s1	AERGOPXVHFXTRA-ZEQRLZLVSA-N	242665	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(ethylamino)butanamide hydrochloride::US10053431, 155	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242665&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077301	376221458							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489500	COc1ccc2ccccc2c1CN1c2ccccc2N(C[C@H](NC(=O)[C@H](C)N)C1=O)C(=O)c1ccc(N)cc1	InChI=1S/C31H31N5O4/c1-19(32)29(37)34-25-18-36(30(38)21-11-14-22(33)15-12-21)27-10-6-5-9-26(27)35(31(25)39)17-24-23-8-4-3-7-20(23)13-16-28(24)40-2/h3-16,19,25H,17-18,32-33H2,1-2H3,(H,34,37)/t19-,25-/m0/s1	OLTFAVQZOZOOLQ-DFBJGRDBSA-N	242666	(S)-2-amino-N—((S)-5-(4-aminobenzoyl)-1-((2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)propanamide::US10053431, 65	E3 ubiquitin-protein ligase XIAP [241-356]			 23570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242666&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076749	376221459					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489502	CCN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C29H33BrN4O6S/c1-5-31-18(2)28(36)32-23-16-33(27(35)17-41(4,38)39)24-11-6-7-12-25(24)34(29(23)37)15-21-19-9-8-10-22(30)20(19)13-14-26(21)40-3/h6-14,18,23,31H,5,15-17H2,1-4H3,(H,32,36)/t18-,23-/m0/s1	FGSKCZWRRAOLCH-MBSDFSHPSA-N	242667	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(ethylamino)propanamide hydrochloride::US10053431, 156	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242667&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077327	376221460							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489504	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H31N5O5/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-35-28-10-6-7-11-29(28)36(19-27(32(35)40)34-30(38)21(2)33-3)31(39)23-14-16-24(17-15-23)37(41)42/h4-17,21,27,33H,18-19H2,1-3H3,(H,34,38)/t21-,27-/m0/s1	HAOHFLWHICJWHC-IDISGSTGSA-N	242668	(2S)-2-(methylamino)-N-[(3S)-5-[(2-methyl-1-naphthyl)methyl]-1-(4-nitrobenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]propanamide hydrochloride::US10053431, 66	E3 ubiquitin-protein ligase XIAP [241-356]			 48300					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242668&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076995	376221461							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489506	CCN[C@@H](CC)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C30H35BrN4O6S/c1-5-23(32-6-2)29(37)33-24-17-34(28(36)18-42(4,39)40)25-9-7-8-10-26(25)35(30(24)38)16-22-21-13-12-20(31)15-19(21)11-14-27(22)41-3/h7-15,23-24,32H,5-6,16-18H2,1-4H3,(H,33,37)/t23-,24-/m0/s1	IUNPGRYHIFZUCJ-ZEQRLZLVSA-N	242669	(S)-N-((S)-1-((6-bromo-2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(ethylamino)butanamide hydrochloride::US10053431, 157	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242669&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076671	376221462							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489508	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O3/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-36-28-10-6-7-11-29(28)37(31(39)23-14-16-24(33)17-15-23)19-27(32(36)40)35-30(38)21(2)34-3/h4-17,21,27,34H,18-19,33H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	GQDZIRQSHUDXHH-IDISGSTGSA-N	242670	(S)—N—((S)-5-(4-aminobenzoyl)-1-((2-methylnaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 67	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242670&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077317	376221463							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489510	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc3cn[nH]c3c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O			242671	(2S)-N-[(3S)-1-(1H-indazole-6-carbonyl)- 5-[(2-methylnaphthalen-1-yl)methyl]-4- oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]- 2-(methylamino)propanamide::US10053431, 158	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242671&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531434	376221464							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489512	C[C@@H](N)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H32N4O4/c1-20-12-13-24-8-4-5-9-26(24)27(20)18-36-29-10-6-7-11-30(29)37(19-28(33(36)41)35-31(39)21(2)34)32(40)25-16-14-23(15-17-25)22(3)38/h4-17,21,28H,18-19,34H2,1-3H3,(H,35,39)/t21-,28+/m1/s1	HDRZXKUDFVCNST-PIKZIKFNSA-N	242672	(R)—N—((S)-5-(4-acetylbenzoyl)-1-((2-methylnaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 68	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242672&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552254	376221465							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489514	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O	InChI=1S/C31H31N7O5S/c1-20(33-2)30(40)34-24-18-36(29(39)19-44(3,42)43)27-14-8-9-15-28(27)37(31(24)41)17-23-22-11-5-7-13-26(22)38(35-23)25-12-6-4-10-21(25)16-32/h4-15,20,24,33H,17-19H2,1-3H3,(H,34,40)/t20-,24-/m0/s1	RNAGNPWGXYIJQW-RDPSFJRHSA-N	242673	(S)-N-((S)-1-((1-(2-cyanophenyl)-1H- indazol-3-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 159	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242673&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077411	376221466							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489516	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OCC(F)(F)F)ccc3ccccc23)C1=O	InChI=1S/C35H33F3N4O5/c1-21(39-3)32(44)40-28-19-42(33(45)25-14-12-23(13-15-25)22(2)43)30-11-7-6-10-29(30)41(34(28)46)18-27-26-9-5-4-8-24(26)16-17-31(27)47-20-35(36,37)38/h4-17,21,28,39H,18-20H2,1-3H3,(H,40,44)/t21-,28-/m0/s1	URMJPEDUVJVTIM-KMRXNPHXSA-N	242674	US10053431, 69a	E3 ubiquitin-protein ligase XIAP [241-356]			 47000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242674&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076549	376221467							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489518	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O)C#N	InChI=1S/C29H30BrN5O6S/c1-17(32-2)28(37)33-23-15-34(27(36)16-42(4,39)40)25-12-18(13-31)8-10-24(25)35(29(23)38)14-21-19-6-5-7-22(30)20(19)9-11-26(21)41-3/h5-12,17,23,32H,14-16H2,1-4H3,(H,33,37)/t17-,23-/m0/s1	WEPCTAAUSDCYCZ-SBUREZEXSA-N	242675	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-5-(2-(methylsulfonyl)acetyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 160	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242675&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531577	376221468							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489520	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OCC(F)(F)F)c[n+]([O-])c3ccccc23)C1=O	InChI=1S/C34H32F3N5O6/c1-20(38-3)31(44)39-26-17-41(32(45)23-14-12-22(13-15-23)21(2)43)29-11-7-6-10-28(29)40(33(26)46)16-25-24-8-4-5-9-27(24)42(47)18-30(25)48-19-34(35,36)37/h4-15,18,20,26,38H,16-17,19H2,1-3H3,(H,39,44)/t20-,26-/m0/s1	NAPUAFOAUICUGC-FNZWTVRRSA-N	242676	4-(((S)-5-(4-Acetylbenzoyl)-3-((S)-2-(methylamino)propanamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)methyl)-3-(2,2,2-trifluoroethoxy)quinoline 1-oxide hydrochloride::US10053431, 70	E3 ubiquitin-protein ligase XIAP [241-356]			 52940					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242676&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531401	376221469							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489522	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C32H30N8O5S/c1-20(35-2)31(42)36-25-18-38(30(41)19-46(3,44)45)29-14-21(15-33)12-13-28(29)39(32(25)43)17-24-23-9-5-7-11-27(23)40(37-24)26-10-6-4-8-22(26)16-34/h4-14,20,25,35H,17-19H2,1-3H3,(H,36,42)/t20-,25-/m0/s1	YEBBKUXDMIGMKX-CPJSRVTESA-N	242677	(2S)-N-[(3S)-7-cyano-1-[[1-(2- cyanophenyl)indazol-3-yl]methyl]-5-(2- methylsulfonylacetyl)-2-oxo-3,4-dihydro- 1,5-benzodiazepin-3-yl]-2- (methylamino)propanamide;2,2,2- trifluoroacetic acid::US10053431, 161	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242677&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531392	376221470							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489524	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2noc3ccccc23)C1=O	InChI=1S/C28H28N6O4/c1-17(30-2)26(35)31-22-16-33(27(36)18-11-13-19(29)14-12-18)23-8-4-5-9-24(23)34(28(22)37)15-21-20-7-3-6-10-25(20)38-32-21/h3-14,17,22,30H,15-16,29H2,1-2H3,(H,31,35)/t17-,22-/m0/s1	TZQFENVHHXGDDJ-JTSKRJEESA-N	242678	(S)—N—((S)-5-(4-Aminobenzoyl)-1-(benzo[d]isoxazol-3-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 71	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242678&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077019	376221471							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489526	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C38H32N8O4/c1-23(41-3)36(48)42-31-22-45(37(49)27-15-13-26(14-16-27)24(2)47)35-18-25(19-39)12-17-34(35)44(38(31)50)21-30-29-9-5-7-11-33(29)46(43-30)32-10-6-4-8-28(32)20-40/h4-18,23,31,41H,21-22H2,1-3H3,(H,42,48)/t23-,31-/m0/s1	HBKKLPXJCFYOFR-FWUCURJTSA-N	242679	(S)-N-((S)-5-(4-acetylbenzoyl)-7-cyano- 1-((1-(2-cyanophenyl)-1H-indazol-3- yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 162	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242679&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077308	376221472							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489528	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(=O)OC)c2ccccc2N(Cc2noc3ccccc23)C1=O	InChI=1S/C30H29N5O6/c1-18(31-2)27(36)32-23-17-34(28(37)19-12-14-20(15-13-19)30(39)40-3)24-9-5-6-10-25(24)35(29(23)38)16-22-21-8-4-7-11-26(21)41-33-22/h4-15,18,23,31H,16-17H2,1-3H3,(H,32,36)/t18-,23-/m0/s1	JMSWMUZCNLHGNA-MBSDFSHPSA-N	242680	Methyl 4-((S)-5-(benzo[d]isoxazol-3-ylmethyl)-3-((S)-2-(methylamino)propanamido)-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-1-carbonyl)benzoate hydrochloride::US10053431, 72	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242680&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531414	376221473							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489530	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C36H29FN8O3/c1-22(40-2)34(46)41-29-21-44(35(47)24-12-14-26(37)15-13-24)33-17-23(18-38)11-16-32(33)43(36(29)48)20-28-27-8-4-6-10-31(27)45(42-28)30-9-5-3-7-25(30)19-39/h3-17,22,29,40H,20-21H2,1-2H3,(H,41,46)/t22-,29-/m0/s1	SQGMCBHFFRQSCB-ZTOMLWHTSA-N	242681	(S)-N-((S)-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-5- (4-fluorobenzoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 163	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242681&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076645	376221474							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489532	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C33H30BrN5O4/c1-20(36-2)31(40)37-27-19-39(32(41)22-13-11-21(17-35)12-14-22)29-10-5-4-9-28(29)38(33(27)42)18-25-23-7-6-8-26(34)24(23)15-16-30(25)43-3/h4-16,20,27,36H,18-19H2,1-3H3,(H,37,40)/t20-,27-/m0/s1	LNKXDVFBJVCXBW-DCFHFQCYSA-N	242682	(S)—N—((S)-1-((5-Bromo-2-methoxynaphthalen-1-yl)methyl)-5-(4-cyanobenzoyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 73	E3 ubiquitin-protein ligase XIAP [241-356]			 28250					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=242682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=242682&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076595	376221475							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489534	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2nn(C)c3ccccc23)C1=O)C#N	InChI=1S/C26H29N7O5S/c1-16(28-2)25(35)29-20-14-32(24(34)15-39(4,37)38)23-11-17(12-27)9-10-22(23)33(26(20)36)13-19-18-7-5-6-8-21(18)31(3)30-19/h5-11,16,20,28H,13-15H2,1-4H3,(H,29,35)/t16-,20-/m0/s1	QSEIHNAIPUXQGH-JXFKEZNVSA-N	243076	(S)-N-((S)-7-cyano-1-((1-methyl-1H- indazol-3-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 164	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243076&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076701	376221476							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489536	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2ccccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C33H29F2N5O4/c1-20(37-2)30(41)38-26-19-40(31(42)23-13-11-21(17-36)12-14-23)28-10-6-5-9-27(28)39(32(26)43)18-25-24-8-4-3-7-22(24)15-16-29(25)44-33(34)35/h3-16,20,26,33,37H,18-19H2,1-2H3,(H,38,41)/t20-,26-/m0/s1	MYOBQHKFHNAVIK-FNZWTVRRSA-N	243077	(S)—N—((S)-5-(4-Cyanobenzoyl)-1-((2-(difluoromethoxy)naphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide::US10053431, 74	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243077&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076803	376221477							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489538	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2c(C)ccc3ccccc23)C1=O)C#N	InChI=1S/C29H31N5O5S/c1-18-9-11-21-7-5-6-8-22(21)23(18)15-34-25-12-10-20(14-30)13-26(25)33(27(35)17-40(4,38)39)16-24(29(34)37)32-28(36)19(2)31-3/h5-13,19,24,31H,15-17H2,1-4H3,(H,32,36)/t19-,24-/m0/s1	AGGFNBSBTKKUBE-CYFREDJKSA-N	243090	(S)-N-((S)-7-cyano-1-((2- methylnaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 165	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243090&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076571	376221478							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489540	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H30BrFN4O4/c1-19(35-2)30(39)36-26-18-38(31(40)20-8-12-23(34)13-9-20)28-7-5-4-6-27(28)37(32(26)41)17-25-24-14-11-22(33)16-21(24)10-15-29(25)42-3/h4-16,19,26,35H,17-18H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	IYAXXUOLQDPMLM-SIBVEZHUSA-N	50441829	CHEMBL2436331::US10053431, 75a	E3 ubiquitin-protein ligase XIAP [241-356]			 27000					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441829&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711251	175454146		CHEMBL2436331				ZINC96285536	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489542	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2c(OC)ccc3ccccc23)C1=O)C#N	InChI=1S/C29H31N5O6S/c1-18(31-2)28(36)32-23-16-33(27(35)17-41(4,38)39)25-13-19(14-30)9-11-24(25)34(29(23)37)15-22-21-8-6-5-7-20(21)10-12-26(22)40-3/h5-13,18,23,31H,15-17H2,1-4H3,(H,32,36)/t18-,23-/m0/s1	LTHJWVFDLNDYAO-MBSDFSHPSA-N	243092	(S)-N-((S)-7-cyano-1-((2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 166	E3 ubiquitin-protein ligase XIAP [241-356]			 43560					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243092&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077051	376221480							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489544	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccnc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H32BrN5O4/c1-20(34-2)31(40)36-26-19-37(30(39)15-21-7-6-14-35-17-21)27-8-4-5-9-28(27)38(32(26)41)18-25-24-12-11-23(33)16-22(24)10-13-29(25)42-3/h4-14,16-17,20,26,34H,15,18-19H2,1-3H3,(H,36,40)/t20-,26-/m0/s1	YEFFLKUAMCNGBI-FNZWTVRRSA-N	50441830	CHEMBL2436210::US10053431, 85	E3 ubiquitin-protein ligase XIAP [241-356]			 42700					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441830&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711722	175454147		CHEMBL2436210				ZINC96285537	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489546	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccc(cc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C32H30N8O5S/c1-20(35-2)31(42)36-25-18-38(30(41)19-46(3,44)45)28-13-12-21(15-33)14-29(28)39(32(25)43)17-24-23-9-5-7-11-27(23)40(37-24)26-10-6-4-8-22(26)16-34/h4-14,20,25,35H,17-19H2,1-3H3,(H,36,42)/t20-,25-/m0/s1	MLGYSEOKPCYSHL-CPJSRVTESA-N	243094	(S)-N-((S)-8-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-5- (2-(methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 167	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243094&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531438	376221482							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489548	CN[C@@H](C)C(=O)N[C@H]1CN(Cc2ccccc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H33BrN4O3/c1-21(34-2)31(38)35-27-20-36(18-22-9-5-4-6-10-22)28-11-7-8-12-29(28)37(32(27)39)19-26-25-15-14-24(33)17-23(25)13-16-30(26)40-3/h4-17,21,27,34H,18-20H2,1-3H3,(H,35,38)/t21-,27-/m0/s1	LOLGTAJHBKRVRL-IDISGSTGSA-N	243095	(S)—N—((S)-5-Benzyl-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide trifluoroacetate::US10053431, 77	E3 ubiquitin-protein ligase XIAP [241-356]			 47520					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243095&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077021	376221483							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489550	CN[C@@H](C)C(=O)N[C@H]1CNc2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C29H26N8O2/c1-18(32-2)28(38)34-23-16-33-22-13-19(14-30)11-12-27(22)36(29(23)39)17-24-21-8-4-6-10-26(21)37(35-24)25-9-5-3-7-20(25)15-31/h3-13,18,23,32-33H,16-17H2,1-2H3,(H,34,38)/t18-,23-/m0/s1	CWBVLVWXNPYBBJ-MBSDFSHPSA-N	243096	(S)-N-((S)-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide dihydrochloride::US10053431, 168	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243096&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531569	376221484							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489552	CN[C@@H](C)C(=O)N[C@H]1CN(Cc2ccc(cc2)C#N)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H32BrN5O3/c1-21(36-2)32(40)37-28-20-38(18-23-10-8-22(17-35)9-11-23)29-6-4-5-7-30(29)39(33(28)41)19-27-26-14-13-25(34)16-24(26)12-15-31(27)42-3/h4-16,21,28,36H,18-20H2,1-3H3,(H,37,40)/t21-,28-/m0/s1	VJQUOVDKQYXICT-KMRXNPHXSA-N	243097	(S)—N—((S)-1-((6-Bromo-2-methoxynaphthalen-1-yl)methyl)-5-(4-cyanobenzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide trifluoroacetate::US10053431, 78	E3 ubiquitin-protein ligase XIAP [241-356]			 17080					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243097&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076739	376221485							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489554	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C31H28N8O3/c1-19(34-3)30(41)35-25-18-37(20(2)40)29-14-21(15-32)12-13-28(29)38(31(25)42)17-24-23-9-5-7-11-27(23)39(36-24)26-10-6-4-8-22(26)16-33/h4-14,19,25,34H,17-18H2,1-3H3,(H,35,41)/t19-,25-/m0/s1	QGHSMBWRUAZMSH-DFBJGRDBSA-N	243098	(S)-N-((S)-5-acetyl-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 169	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243098&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076889	376221486							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489556	CCC(NC)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C35H35BrN4O5/c1-5-28(37-3)33(42)38-29-20-40(34(43)23-12-10-22(11-13-23)21(2)41)31-9-7-6-8-30(31)39(35(29)44)19-27-26-16-15-25(36)18-24(26)14-17-32(27)45-4/h6-18,28-29,37H,5,19-20H2,1-4H3,(H,38,42)/t28?,29-/m0/s1	DAVMYBGHJUAMGX-XIJSCUBXSA-N	243099	(S)—N—((S)-5-(4-Acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)butanamide hydrochloride::US10053431, 79	E3 ubiquitin-protein ligase XIAP [241-356]			 3479					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243099&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			134823046	376221487							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489558	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C2CCOCC2)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C35H34N8O4/c1-22(38-2)33(44)39-28-21-42(34(45)24-13-15-47-16-14-24)32-17-23(18-36)11-12-31(32)41(35(28)46)20-27-26-8-4-6-10-30(26)43(40-27)29-9-5-3-7-25(29)19-37/h3-12,17,22,24,28,38H,13-16,20-21H2,1-2H3,(H,39,44)/t22-,28-/m0/s1	JPSHIAQRZFQBBB-DWACAAAGSA-N	243100	(S)-N-((S)-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-2- oxo-5-(tetrahydro-2H-pyran-4-carbonyl)- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 170	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243100&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077347	376221488							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489560	CCN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C35H35BrN4O5/c1-5-37-21(2)33(42)38-29-20-40(34(43)24-12-10-23(11-13-24)22(3)41)31-9-7-6-8-30(31)39(35(29)44)19-28-27-16-15-26(36)18-25(27)14-17-32(28)45-4/h6-18,21,29,37H,5,19-20H2,1-4H3,(H,38,42)/t21-,29-/m0/s1	CZTUMEJKHNBRMB-LGGPFLRQSA-N	243101	(S)—N—((S)-5-(4-Acetylbenzoyl)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(ethylamino)propanamide hydrochloride::US10053431, 80	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243101&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077123	376221489							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489562	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccc(cc2N(Cc2c(OC)ccc3ccccc23)C1=O)C#N	InChI=1S/C29H31N5O6S/c1-18(31-2)28(36)32-23-16-33(27(35)17-41(4,38)39)24-11-9-19(14-30)13-25(24)34(29(23)37)15-22-21-8-6-5-7-20(21)10-12-26(22)40-3/h5-13,18,23,31H,15-17H2,1-4H3,(H,32,36)/t18-,23-/m0/s1	CFDGAKTVRXQYIB-MBSDFSHPSA-N	243102	(S)-N-((S)-8-cyano-1-((2- methoxynaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 171	E3 ubiquitin-protein ligase XIAP [241-356]			 41240					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243102&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076723	376221490							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489564	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C28H31BrN4O6S/c1-17(30-2)27(35)31-22-15-32(26(34)16-40(4,37)38)23-10-5-6-11-24(23)33(28(22)36)14-20-18-8-7-9-21(29)19(18)12-13-25(20)39-3/h5-13,17,22,30H,14-16H2,1-4H3,(H,31,35)/t17-,22-/m0/s1	FGIFICWCAGQNOA-JTSKRJEESA-N	243103	(S)—N—((S)-1-((5-Bromo-2-methoxynaphthalen-1-yl)methyl)-5-(2-(methylsulfonyl)acetyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 81	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243103&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076667	376221491							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489566	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccc(cc2N(Cc2c(C)ccc3ccccc23)C1=O)C#N	InChI=1S/C29H31N5O5S/c1-18-9-11-21-7-5-6-8-22(21)23(18)15-34-26-13-20(14-30)10-12-25(26)33(27(35)17-40(4,38)39)16-24(29(34)37)32-28(36)19(2)31-3/h5-13,19,24,31H,15-17H2,1-4H3,(H,32,36)/t19-,24-/m0/s1	GOQZTJDTWHPUJD-CYFREDJKSA-N	243104	(S)-N-((S)-8-cyano-1-((2- methylnaphthalen-1-yl)methyl)-5-(2- (methylsulfonyl)acetyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 172	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243104&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077081	376221492							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489568	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C28H32N4O6S/c1-18(29-2)27(34)30-22-16-31(26(33)17-39(4,36)37)23-11-7-8-12-24(23)32(28(22)35)15-21-20-10-6-5-9-19(20)13-14-25(21)38-3/h5-14,18,22,29H,15-17H2,1-4H3,(H,30,34)/t18-,22-/m0/s1	OGXPHJKZQFVFOP-AVRDEDQJSA-N	243105	(S)—N—((S)-1-((2-Methoxynaphthalen-1-yl)methyl)-5-(2-(methylsulfonyl)acetyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 82	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243105&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076860	376221493							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489570	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCOC)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C33H32N8O4/c1-21(36-2)32(43)37-26-20-39(31(42)14-15-45-3)30-16-22(17-34)12-13-29(30)40(33(26)44)19-25-24-9-5-7-11-28(24)41(38-25)27-10-6-4-8-23(27)18-35/h4-13,16,21,26,36H,14-15,19-20H2,1-3H3,(H,37,43)/t21-,26-/m0/s1	NWMLCUDSFNQPNC-LVXARBLLSA-N	243106	(S)-N-((S)-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-5- (3-methoxypropanoyl)-2-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 173	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243106&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076841	376221494							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489572	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C28H30F2N4O6S/c1-17(31-2)26(36)32-21-15-33(25(35)16-41(3,38)39)22-10-6-7-11-23(22)34(27(21)37)14-20-19-9-5-4-8-18(19)12-13-24(20)40-28(29)30/h4-13,17,21,28,31H,14-16H2,1-3H3,(H,32,36)/t17-,21-/m0/s1	DVMSAXASHGXOKB-UWJYYQICSA-N	243107	(S)—N—((S)-1-((2-(Difluoromethoxy)naphthalen-1-yl)methyl)-5-(2-(methylsulfonyl)acetyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 83	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243107&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076900	376221495							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489574	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccncc2)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C#N	InChI=1S/C35H29N9O3/c1-22(38-2)33(45)40-28-21-43(34(46)24-13-15-39-16-14-24)32-17-23(18-36)11-12-31(32)42(35(28)47)20-27-26-8-4-6-10-30(26)44(41-27)29-9-5-3-7-25(29)19-37/h3-17,22,28,38H,20-21H2,1-2H3,(H,40,45)/t22-,28-/m0/s1	QZIVNKNQWYOBJD-DWACAAAGSA-N	243108	(S)-N-((S)-7-cyano-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-5- isonicotinoyl-2-oxo-2,3,4,5-tetrahydro- 1H-benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide dihydrochloride::US10053431, 174	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243108&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077220	376221496							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489576	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H30BrN5O4/c1-20(36-2)31(40)37-27-19-39(32(41)22-10-8-21(17-35)9-11-22)29-7-5-4-6-28(29)38(33(27)42)18-26-25-14-13-24(34)16-23(25)12-15-30(26)43-3/h4-16,20,27,36H,18-19H2,1-3H3,(H,37,40)/t20-,27-/m0/s1	QIVSDYYFNPWSEF-DCFHFQCYSA-N	243109	(2S)—N-[(3S)-5-[[6-bromo-2-(trideuteriomethoxy)-1-naphthyl]methyl]-1-(4-cyanobenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide hydrochloride::US10053431, 13p::US10053431, 84	E3 ubiquitin-protein ligase XIAP [241-356]			 32750					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243109&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076961	376221497							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489578	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2ccc(cc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O)C#N	InChI=1S/C29H30BrN5O6S/c1-17(32-2)28(37)33-23-15-34(27(36)16-42(4,39)40)24-10-8-18(13-31)12-25(24)35(29(23)38)14-21-19-6-5-7-22(30)20(19)9-11-26(21)41-3/h5-12,17,23,32H,14-16H2,1-4H3,(H,33,37)/t17-,23-/m0/s1	JUAPCEVTUXIEDE-SBUREZEXSA-N	243110	(S)-N-((S)-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-8- cyano-5-(2-(methylsulfonyl)acetyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 175	E3 ubiquitin-protein ligase XIAP [241-356]			 17590					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243110&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531489	376221498							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489580	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccnc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H32BrN5O4/c1-20(34-2)31(40)36-26-19-37(30(39)15-21-7-6-14-35-17-21)27-8-4-5-9-28(27)38(32(26)41)18-25-24-12-11-23(33)16-22(24)10-13-29(25)42-3/h4-14,16-17,20,26,34H,15,18-19H2,1-3H3,(H,36,40)/t20-,26-/m0/s1	YEFFLKUAMCNGBI-FNZWTVRRSA-N	50441830	CHEMBL2436210::US10053431, 85	E3 ubiquitin-protein ligase XIAP [241-356]			 33910					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441830&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711722	175454147		CHEMBL2436210				ZINC96285537	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489582	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2c(ccc3c(cccc23)C#N)C2CC2)C1=O)C#N	InChI=1S/C31H30N6O3/c1-18(34-3)30(39)35-27-17-36(19(2)38)29-13-20(14-32)7-12-28(29)37(31(27)40)16-26-23(21-8-9-21)10-11-24-22(15-33)5-4-6-25(24)26/h4-7,10-13,18,21,27,34H,8-9,16-17H2,1-3H3,(H,35,39)/t18-,27-/m0/s1	SRWSQAJBSMBUEO-MYUZEXMDSA-N	243112	(S)-N-((S)-5-acetyl-7-cyano-1-((5-cyano- 2-cyclopropylnaphthalen-1-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 176	E3 ubiquitin-protein ligase XIAP [241-356]			 25590					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243112&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076607	376221500							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489584	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC2CCOCC2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H37BrN4O5/c1-20(34-2)31(39)35-26-19-36(30(38)16-21-12-14-42-15-13-21)27-6-4-5-7-28(27)37(32(26)40)18-25-24-10-9-23(33)17-22(24)8-11-29(25)41-3/h4-11,17,20-21,26,34H,12-16,18-19H2,1-3H3,(H,35,39)/t20-,26-/m0/s1	AMDHWKSCEMDFGR-FNZWTVRRSA-N	243113	(S)—N—((S)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-5-(2-(tetrahydro-2H-pyran-4-yl)acetyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 86	E3 ubiquitin-protein ligase XIAP [241-356]			 49620					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243113&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077146	376221501							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489586	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2nn(-c3ccccc3C#N)c3ccccc23)C1=O)C(F)(F)F	InChI=1S/C31H28F3N7O3/c1-18(36-3)29(43)37-24-17-39(19(2)42)28-14-21(31(32,33)34)12-13-27(28)40(30(24)44)16-23-22-9-5-7-11-26(22)41(38-23)25-10-6-4-8-20(25)15-35/h4-14,18,24,36H,16-17H2,1-3H3,(H,37,43)/t18-,24-/m0/s1	UUYJEDVPKLBWTH-UUOWRZLLSA-N	243114	(S)-N-((S)-5-acetyl-1-((1-(2- cyanophenyl)-1H-indazol-3-yl)methyl)-2- oxo-7-(trifluoromethyl)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 177	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243114&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076573	376221502							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489588	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC2CCOCC2)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C32H37BrN4O5/c1-20(34-2)31(39)35-26-19-36(30(38)17-21-13-15-42-16-14-21)27-9-4-5-10-28(27)37(32(26)40)18-24-22-7-6-8-25(33)23(22)11-12-29(24)41-3/h4-12,20-21,26,34H,13-19H2,1-3H3,(H,35,39)/t20-,26-/m0/s1	DZPAEBGAFMUCAU-FNZWTVRRSA-N	243115	(S)—N—((S)-1-((5-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-5-(2-(tetrahydro-2H-pyran-4-yl)acetyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 87	E3 ubiquitin-protein ligase XIAP [241-356]			 54420					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243115&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077304	376221503							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489590	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(N)cc2)c2ccccc2N(Cc2c(OCCF)ccc3ccccc23)C1=O	InChI=1S/C33H34FN5O4/c1-21(36-2)31(40)37-27-20-39(32(41)23-11-14-24(35)15-12-23)29-10-6-5-9-28(29)38(33(27)42)19-26-25-8-4-3-7-22(25)13-16-30(26)43-18-17-34/h3-16,21,27,36H,17-20,35H2,1-2H3,(H,37,40)/t21-,27-/m0/s1	FTBUPFGGJCLZQI-IDISGSTGSA-N	243116	(2S)-N-[(3S)-1-(4-aminobenzoyl)-5-[[2- (2-fluoroethoxy)naphthalen-1-yl]methyl]- 4-oxo-2,3-dihydro-1,5-benzodiazepin-3- yl]-2- (methylamino)propanamide;hydrochloride::US10053431, 178	E3 ubiquitin-protein ligase XIAP [241-356]			 16090					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243116&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531507	376221504							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489592	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2cccnc2)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C32H32BrN5O4/c1-20(34-2)31(40)36-26-19-37(30(39)16-21-8-7-15-35-17-21)27-11-4-5-12-28(27)38(32(26)41)18-24-22-9-6-10-25(33)23(22)13-14-29(24)42-3/h4-15,17,20,26,34H,16,18-19H2,1-3H3,(H,36,40)/t20-,26-/m0/s1	MGGITSBKIMQADG-FNZWTVRRSA-N	243117	(S)—N—((S)-1-((5-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-5-(2-(pyridin-3-yl)acetyl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(methylamino)propanamide hydrochloride::US10053431, 88	E3 ubiquitin-protein ligase XIAP [241-356]			 39890					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243117&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076791	376221505							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489594	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O)C#N	InChI=1S/C28H28BrN5O4/c1-16(31-3)27(36)32-23-15-33(17(2)35)25-12-18(13-30)8-10-24(25)34(28(23)37)14-21-19-6-5-7-22(29)20(19)9-11-26(21)38-4/h5-12,16,23,31H,14-15H2,1-4H3,(H,32,36)/t16-,23-/m0/s1	UCZNEGUUTPQZCS-HJPURHCSSA-N	243118	(S)-N-((S)-5-acetyl-1-((5-bromo-2- methoxynaphthalen-1-yl)methyl)-7- cyano-2-oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 179	E3 ubiquitin-protein ligase XIAP [241-356]			 33120					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243118&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077202	376221506							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489596	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccn2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C31H30BrN5O4/c1-19(33-2)29(38)35-25-18-37(30(39)24-8-6-7-15-34-24)27-10-5-4-9-26(27)36(31(25)40)17-23-22-13-12-21(32)16-20(22)11-14-28(23)41-3/h4-16,19,25,33H,17-18H2,1-3H3,(H,35,38)/t19-,25-/m0/s1	TWYQHECIANXYGO-DFBJGRDBSA-N	243119	US10053431, 89a	E3 ubiquitin-protein ligase XIAP [241-356]			 44490					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243119&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076554	376221507							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489598	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C2CCOCC2)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C#N	InChI=1S/C33H36N6O4/c1-20(35-2)31(40)37-28-19-39(32(41)23-11-13-43-14-12-23)30-15-21(16-34)7-10-29(30)38(33(28)42)18-26-24-5-3-4-6-27(24)36-17-25(26)22-8-9-22/h3-7,10,15,17,20,22-23,28,35H,8-9,11-14,18-19H2,1-2H3,(H,37,40)/t20-,28-/m0/s1	QUKRKMDFJUXCAY-MMTVBGGISA-N	243120	(S)-N-((S)-7-cyano-1-((3- cyclopropylquinolin-4-yl)methyl)-2-oxo- 5-(telrahydro-2H-pyran-4-carbonyl)- 2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 180	E3 ubiquitin-protein ligase XIAP [241-356]			 16510					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243120&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076897	376221508							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489600	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2F)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H30BrFN4O4/c1-19(35-2)30(39)36-26-18-38(31(40)23-8-4-5-9-25(23)34)28-11-7-6-10-27(28)37(32(26)41)17-24-22-14-13-21(33)16-20(22)12-15-29(24)42-3/h4-16,19,26,35H,17-18H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	AZUWGFNMKLGVNC-SIBVEZHUSA-N	50441825	CHEMBL2436333::US10053431, 90a	E3 ubiquitin-protein ligase XIAP [241-356]			 24310					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441825&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711255	175454142		CHEMBL2436333				ZINC96285532	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489602	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccncc2)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C#N	InChI=1S/C33H31N7O3/c1-20(35-2)31(41)38-28-19-40(32(42)23-11-13-36-14-12-23)30-15-21(16-34)7-10-29(30)39(33(28)43)18-26-24-5-3-4-6-27(24)37-17-25(26)22-8-9-22/h3-7,10-15,17,20,22,28,35H,8-9,18-19H2,1-2H3,(H,38,41)/t20-,28-/m0/s1	LKTPSSFKOOCJLH-MMTVBGGISA-N	243122	(S)-N-((S)-7-cyano-1-((3- cyclopropylquinolin-4-yl)methyl)-5- isonicotinoyl-2-oxo-2,3,4,5-tetrahydro- 1H-benzo[bl[1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 181	E3 ubiquitin-protein ligase XIAP [241-356]			 16280					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243122&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076601	376221510							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489604	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H31BrN4O4/c1-20(34-2)30(38)35-26-19-37(31(39)21-9-5-4-6-10-21)28-12-8-7-11-27(28)36(32(26)40)18-25-24-15-14-23(33)17-22(24)13-16-29(25)41-3/h4-17,20,26,34H,18-19H2,1-3H3,(H,35,38)/t20-,26-/m0/s1	VEPLHDWLOOVFAN-FNZWTVRRSA-N	50441834	CHEMBL2436330::US10053431, 91a	E3 ubiquitin-protein ligase XIAP [241-356]			 24770					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441834&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711249	175454151		CHEMBL2436330				ZINC96285541	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489606	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2c(OC)ccc3c(cccc23)C#N)C1=O)C#N	InChI=1S/C29H28N6O4/c1-17(32-3)28(37)33-24-16-34(18(2)36)26-12-19(13-30)8-10-25(26)35(29(24)38)15-23-22-7-5-6-20(14-31)21(22)9-11-27(23)39-4/h5-12,17,24,32H,15-16H2,1-4H3,(H,33,37)/t17-,24-/m0/s1	JRTOXIMJENDGBX-XDHUDOTRSA-N	243124	(S)-N-((S)-5-acetyl-7-cyano-1-((5-cyano- 2-methoxynaphthalen-1-yl)methyl)-2- oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 182	E3 ubiquitin-protein ligase XIAP [241-356]			 32390					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243124&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076890	376221512							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489608	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(F)cc2)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C32H30BrFN4O4/c1-19(35-2)30(39)36-26-18-38(31(40)20-11-13-21(34)14-12-20)28-10-5-4-9-27(28)37(32(26)41)17-24-22-7-6-8-25(33)23(22)15-16-29(24)42-3/h4-16,19,26,35H,17-18H2,1-3H3,(H,36,39)/t19-,26-/m0/s1	RGMOVTZDXIGOSP-SIBVEZHUSA-N	243125	(S)-N-[(S)-1-(5-Bromo-2-methoxy-naphthalen-1-ylmethyl)-5-(4-fluoro-benzoyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 92	E3 ubiquitin-protein ligase XIAP [241-356]			 13750					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243125&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077212	376221513							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489610	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C29H30F3N5O3/c1-16(33-3)27(39)35-24-15-36(17(2)38)26-12-19(29(30,31)32)10-11-25(26)37(28(24)40)14-22-20-6-4-5-7-23(20)34-13-21(22)18-8-9-18/h4-7,10-13,16,18,24,33H,8-9,14-15H2,1-3H3,(H,35,39)/t16-,24-/m0/s1	DRGYOURAEOQZMK-FYSMJZIKSA-N	243126	(S)-N-((S)-5-acetyl-1-((3- cyclopropylquinolin-4-yl)methyl)-2-oxo- 7-(trifluoromethyl)-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 183	E3 ubiquitin-protein ligase XIAP [241-356]			 27490					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243126&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076598	376221514							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489612	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C)cc2)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C33H33BrN4O4/c1-20-12-14-22(15-13-20)32(40)38-19-27(36-31(39)21(2)35-3)33(41)37(28-10-5-6-11-29(28)38)18-25-23-8-7-9-26(34)24(23)16-17-30(25)42-4/h5-17,21,27,35H,18-19H2,1-4H3,(H,36,39)/t21-,27-/m0/s1	USAQVOUWJOLJBF-IDISGSTGSA-N	243127	(S)—N—[(S)-1-(5-Bromo-2-methoxy-naphthalen-1-ylmethyl)-5-(4-methyl-benzoyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 93	E3 ubiquitin-protein ligase XIAP [241-356]			 47570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243127&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076954	376221515							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489614	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)C2CCOCC2)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C33H36F3N5O4/c1-19(37-2)30(42)39-27-18-41(31(43)21-11-13-45-14-12-21)29-15-22(33(34,35)36)9-10-28(29)40(32(27)44)17-25-23-5-3-4-6-26(23)38-16-24(25)20-7-8-20/h3-6,9-10,15-16,19-21,27,37H,7-8,11-14,17-18H2,1-2H3,(H,39,42)/t19-,27-/m0/s1	RWPQAGGULLKRTG-PPHZAIPVSA-N	243128	(S)-N-((S)-1-((3-cyclopropylquinolin-4- yl)methyl)-2-oxo-5-(tetrahydro-2H-pyran- 4-carbonyl)-7-(trifluoromethyr)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::US10053431, 184	E3 ubiquitin-protein ligase XIAP [241-356]			 15240					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243128&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531420	376221516							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489616	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C34H35BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-14-12-22(13-15-23)21(2)40)30-11-6-5-10-29(30)38(34(28)43)18-26-24-8-7-9-27(35)25(24)16-17-31(26)44-4/h5-17,20-21,28,36,40H,18-19H2,1-4H3,(H,37,41)/t20-,21?,28-/m0/s1	RAOMAPTYSDNIEA-ZWCJHOFGSA-N	243129	(S)—N—{(S)-1-(5-Bromo-2-methoxy-naphthalen-1-ylmethyl)-5-[4-(1-hydroxy-ethyl)-benzoyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl}-2-methylamino-propionamide, mixture of diastereomers::US10053431, 94	E3 ubiquitin-protein ligase XIAP [241-356]			 46630					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243129&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077007	376221517							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489618	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCOC)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C31H34F3N5O4/c1-18(35-2)29(41)37-25-17-38(28(40)12-13-43-3)27-14-20(31(32,33)34)10-11-26(27)39(30(25)42)16-23-21-6-4-5-7-24(21)36-15-22(23)19-8-9-19/h4-7,10-11,14-15,18-19,25,35H,8-9,12-13,16-17H2,1-3H3,(H,37,41)/t18-,25-/m0/s1	VALZCXFFXPZMRL-BVZFJXPGSA-N	243130	(S)-N-((S)-1-((3-cyclopropylquinolin-4- yl)methyl)-5-(3-methoxypropanoyl)-2- oxo-7-(trifluoromcthyl)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::US10053431, 185	E3 ubiquitin-protein ligase XIAP [241-356]			 33190					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243130&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531394	376221518							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489620	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)(C)O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C35H37BrN4O5/c1-21(37-4)32(41)38-28-20-40(33(42)22-10-13-24(14-11-22)35(2,3)44)30-9-7-6-8-29(30)39(34(28)43)19-27-26-16-15-25(36)18-23(26)12-17-31(27)45-5/h6-18,21,28,37,44H,19-20H2,1-5H3,(H,38,41)/t21-,28-/m0/s1	SFVIFIZOVPTBPV-KMRXNPHXSA-N	243131	(S)—N—{(S)-1-(6-Bromo-2-methoxy-naphthalen-1-ylmethyl)-5-[4-(1-hydroxy-1-methyl-ethyl)-benzoyl]-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl}-2-methylamino-propionamide trifluoroacetate::US10053431, 95	E3 ubiquitin-protein ligase XIAP [241-356]			 36280					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243131&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076982	376221519							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489622	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccncc2)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C33H31F3N6O3/c1-19(37-2)30(43)40-27-18-42(31(44)21-11-13-38-14-12-21)29-15-22(33(34,35)36)9-10-28(29)41(32(27)45)17-25-23-5-3-4-6-26(23)39-16-24(25)20-7-8-20/h3-6,9-16,19-20,27,37H,7-8,17-18H2,1-2H3,(H,40,43)/t19-,27-/m0/s1	QZDLAGOCMYYDEZ-PPHZAIPVSA-N	243132	(S)-N-((S)-1-((3-cyclopropylquinolin-4- yl)methyl)-5-isonicolinoyl-2-oxo-7- (trifluoromethyl)-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 186	E3 ubiquitin-protein ligase XIAP [241-356]			 25940					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243132&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077192	376221520							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489624	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(=O)OC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H34N4O5/c1-21-13-14-23-9-5-6-10-26(23)27(21)19-37-29-11-7-8-12-30(29)38(20-28(33(37)41)36-31(39)22(2)35-3)32(40)24-15-17-25(18-16-24)34(42)43-4/h5-18,22,28,35H,19-20H2,1-4H3,(H,36,39)/t22-,28-/m0/s1	JNMRXHHPSYQPFD-DWACAAAGSA-N	243133	US10053431, 96a	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243133&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077155	376221521							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489626	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CS(C)(=O)=O)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C30H32F3N5O5S/c1-17(34-2)28(40)36-24-15-37(27(39)16-44(3,42)43)26-12-19(30(31,32)33)10-11-25(26)38(29(24)41)14-22-20-6-4-5-7-23(20)35-13-21(22)18-8-9-18/h4-7,10-13,17-18,24,34H,8-9,14-16H2,1-3H3,(H,36,40)/t17-,24-/m0/s1	IRHRKXBXQULNII-XDHUDOTRSA-N	243134	(S)-N-((S)-1-((3-cyclopropylquinolin-4- yl)methyl)-5-(2-(methylsulfonyl)acetyl)- 2-oxo-7-(trifluoromethyl)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::US10053431, 187	E3 ubiquitin-protein ligase XIAP [241-356]			 34430					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243134&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531517	376221522							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489628	CCCCC(=O)c1ccc(cc1)C(=O)N1C[C@H](NC(=O)[C@H](C)NC)C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc12	InChI=1S/C37H40N4O4/c1-5-6-15-34(42)27-18-20-28(21-19-27)36(44)41-23-31(39-35(43)25(3)38-4)37(45)40(32-13-9-10-14-33(32)41)22-30-24(2)16-17-26-11-7-8-12-29(26)30/h7-14,16-21,25,31,38H,5-6,15,22-23H2,1-4H3,(H,39,43)/t25-,31-/m0/s1	KDASHTNQMDAKAR-FKAPRUDGSA-N	243135	4-[(S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-benzoic acid hydrochloride::US10053431, 97	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243135&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122552259	376221523							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489630	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCS(C)(=O)=O)c2cc(ccc2N(Cc2c(cnc3ccccc23)C2CC2)C1=O)C(F)(F)F	InChI=1S/C31H34F3N5O5S/c1-18(35-2)29(41)37-25-17-38(28(40)12-13-45(3,43)44)27-14-20(31(32,33)34)10-11-26(27)39(30(25)42)16-23-21-6-4-5-7-24(21)36-15-22(23)19-8-9-19/h4-7,10-11,14-15,18-19,25,35H,8-9,12-13,16-17H2,1-3H3,(H,37,41)/t18-,25-/m0/s1	PAIBPSYLXUOLDV-BVZFJXPGSA-N	243136	(S)-N-((S)-1-((3-cyclopropylquinolin-4- yl)methyl)-5-(3- (methylsulfonyl)propanoyl)-2-oxo-7- (trifluoromethyl)-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide::US10053431, 188	E3 ubiquitin-protein ligase XIAP [241-356]			 25410					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243136&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531462	376221524							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489632	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)c1ccc(NC(C)=O)cc1	InChI=1S/C33H35N5O5S/c1-21-13-14-24-9-5-6-10-27(24)28(21)19-37-30-11-7-8-12-31(30)38(20-29(33(37)41)36-32(40)22(2)34-4)44(42,43)26-17-15-25(16-18-26)35-23(3)39/h5-18,22,29,34H,19-20H2,1-4H3,(H,35,39)(H,36,40)/t22-,29-/m0/s1	ZHJFFSZYMNJXMF-ZTOMLWHTSA-N	243137	US10053431, 98a	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243137&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077226	376221525							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489634	CN[C@@H](C)C(=O)N[C@H]1CN(C(C)=O)c2cc(ccc2N(Cc2c(ccc3c(cccc23)C#N)C2CC2)C1=O)C(F)(F)F	InChI=1S/C31H30F3N5O3/c1-17(36-3)29(41)37-26-16-38(18(2)40)28-13-21(31(32,33)34)9-12-27(28)39(30(26)42)15-25-22(19-7-8-19)10-11-23-20(14-35)5-4-6-24(23)25/h4-6,9-13,17,19,26,36H,7-8,15-16H2,1-3H3,(H,37,41)/t17-,26-/m0/s1	YMTNQVSFQVWBKV-QLXKLKPCSA-N	243138	(S)-N-((S)-5-acetyl-1-((5-cyano-2- cyclopropylnaphthalen-1-yl)methyl)-2- oxo-7-(trifluoromethyl)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide::US10053431, 189	E3 ubiquitin-protein ligase XIAP [241-356]			 29280					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243138&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531406	376221526							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489636	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(N)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H33N5O4/c1-20-12-13-22-8-4-5-9-25(22)26(20)18-37-28-10-6-7-11-29(28)38(19-27(33(37)42)36-31(40)21(2)35-3)32(41)24-16-14-23(15-17-24)30(34)39/h4-17,21,27,35H,18-19H2,1-3H3,(H2,34,39)(H,36,40)/t21-,27-/m0/s1	QBSSKPMNUJHWHC-IDISGSTGSA-N	243139	3-[(S)-3-((S)-2-Methylamino-propionylamino)-5-(2-methyl-naphthalen-1-ylmethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine-1-carbonyl]-benzamide hydrochloride::US10053431, 99	E3 ubiquitin-protein ligase XIAP [241-356]			 33100					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243139&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086446	376221527							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489638	CN[C@@H](C)C(=O)N[C@H]1[C@H](C)N(C(C)=O)c2ccccc2N(CC(=O)Nc2c(F)cccc2F)C1=O	InChI=1S/C24H27F2N5O4/c1-13(27-4)23(34)29-21-14(2)31(15(3)32)19-11-6-5-10-18(19)30(24(21)35)12-20(33)28-22-16(25)8-7-9-17(22)26/h5-11,13-14,21,27H,12H2,1-4H3,(H,28,33)(H,29,34)/t13-,14-,21-/m0/s1	LDVULHNYCCPFER-RXSFTSLZSA-N	243140	(S)-N-((2S,3S)-1-acetyl-5-(2-(2,6- difluorophenylamino)-2-oxoethyl)-2- methyl-4-oxo-2,3,4,5-tetrahydro-1H- benzo[b][1,4]diazepin-3-yl)-2- (methylamino)propanamide hydrochloride::US10053431, 190	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243140&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076773	376221528							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489640	CN[C@@H](C)C(=O)N[C@H]1CN(c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O)S(=O)(=O)N(C)C	InChI=1S/C27H33N5O4S/c1-18-14-15-20-10-6-7-11-21(20)22(18)16-31-24-12-8-9-13-25(24)32(37(35,36)30(4)5)17-23(27(31)34)29-26(33)19(2)28-3/h6-15,19,23,28H,16-17H2,1-5H3,(H,29,33)/t19-,23-/m0/s1	GLPZAIMUFIEEIO-CVDCTZTESA-N	243141	(S)—N—[(S)-5-Dimethylsulfamoyl-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 100	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243141&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077413	376221529							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489642	CN[C@@H](C)C(=O)N[C@H]1[C@H](C)N(C(C)=O)c2ccccc2N(CC(=O)Nc2ccccc2)C1=O	InChI=1S/C24H29N5O4/c1-15(25-4)23(32)27-22-16(2)29(17(3)30)20-13-9-8-12-19(20)28(24(22)33)14-21(31)26-18-10-6-5-7-11-18/h5-13,15-16,22,25H,14H2,1-4H3,(H,26,31)(H,27,32)/t15-,16-,22-/m0/s1	ICDWTUVGOBRBTJ-WCJKSRRJSA-N	243142	(S)-N-((2S,3S)-1-acetyl-2-methyl-4-oxo- 5-(2-oxo-2-(phenylamino)ethyl)-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 191	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243142&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			122531450	376221530							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489644	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccccc2C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H34N4O4/c1-21-17-18-24-11-5-6-13-26(24)28(21)19-37-30-15-9-10-16-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)27-14-8-7-12-25(27)23(3)39/h5-18,22,29,35H,19-20H2,1-4H3,(H,36,40)/t22-,29-/m0/s1	VINJCNHSZRXUCX-ZTOMLWHTSA-N	243143	(S)—N—[(S)-5-(2-Acetyl-benzoyl)-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide::US10053431, 101	E3 ubiquitin-protein ligase XIAP [241-356]			 53430					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243143&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076942	376221531							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489646	CN[C@@H](C)C(=O)N[C@H]1[C@H](C)N(C(C)=O)c2ccccc2N(C(C(=O)Nc2c(F)cccc2F)c2ccccc2)C1=O	InChI=1S/C30H31F2N5O4/c1-17(33-4)28(39)34-25-18(2)36(19(3)38)23-15-8-9-16-24(23)37(30(25)41)27(20-11-6-5-7-12-20)29(40)35-26-21(31)13-10-14-22(26)32/h5-18,25,27,33H,1-4H3,(H,34,39)(H,35,40)/t17-,18-,25-,27?/m0/s1	LOUFNPRJITUWBZ-XPTGHELJSA-N	243144	(2S)-N-((2S,3S)-1-acetyl-5-(2-(2,6- difluorophenylamino)-2-oxo-1- phenylethyl)-2-methyl-4-oxo-2,3,4,5- tetrahydro-1H-benzo[b][1,4]diazepin-3- yl)-2-(methylamino)propanamide hydrochloride::US10053431, 192	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243144&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077197	376221532							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489648	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(CO)cc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H34N4O4/c1-21-12-15-24-8-4-5-9-26(24)27(21)18-36-29-10-6-7-11-30(29)37(32(40)25-16-13-23(20-38)14-17-25)19-28(33(36)41)35-31(39)22(2)34-3/h4-17,22,28,34,38H,18-20H2,1-3H3,(H,35,39)/t22-,28-/m0/s1	YLMVDIJXVNORMX-DWACAAAGSA-N	243145	(S)—N—[(S)-5-(4-Hydroxymethyl-benzoyl)-1-(2-methyl-naphthalen-1-ylmethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl]-2-methylamino-propionamide hydrochloride::US10053431, 102	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243145&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076639	376221533							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489650	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccncc2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H33N5O3/c1-21-12-13-24-8-4-5-9-25(24)26(21)19-37-29-11-7-6-10-28(29)36(30(38)18-23-14-16-34-17-15-23)20-27(32(37)40)35-31(39)22(2)33-3/h4-17,22,27,33H,18-20H2,1-3H3,(H,35,39)/t22-,27-/m0/s1	FDPGTHGFKUIWGT-CUNXSJBXSA-N	243146	US10053431, 13b	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243146&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077132	376221534							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489652	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C33H34N4O5S/c1-21-13-14-23-9-5-6-10-26(23)27(21)19-36-29-11-7-8-12-30(29)37(20-28(33(36)40)35-31(38)22(2)34-3)32(39)24-15-17-25(18-16-24)43(4,41)42/h5-18,22,28,34H,19-20H2,1-4H3,(H,35,38)/t22-,28-/m0/s1	BDRQBDDODAYDGS-DWACAAAGSA-N	243147	US10053431, 13c	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243147&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077270	376221535							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489654	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCC(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C31H36N4O4/c1-20-16-17-23-11-5-6-12-24(23)25(20)18-35-28-14-8-7-13-27(28)34(29(37)15-9-10-21(2)36)19-26(31(35)39)33-30(38)22(3)32-4/h5-8,11-14,16-17,22,26,32H,9-10,15,18-19H2,1-4H3,(H,33,38)/t22-,26-/m0/s1	HYNQGODBKQUEBT-NVQXNPDNSA-N	243148	US10053431, 13d	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243148&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076927	376221536							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489656	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCC(=O)OC)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C32H38N4O5/c1-21-17-18-23-11-5-6-12-24(23)25(21)19-36-28-14-8-7-13-27(28)35(29(37)15-9-10-16-30(38)41-4)20-26(32(36)40)34-31(39)22(2)33-3/h5-8,11-14,17-18,22,26,33H,9-10,15-16,19-20H2,1-4H3,(H,34,39)/t22-,26-/m0/s1	XQQUXXXVYVMKQR-NVQXNPDNSA-N	243149	US10053431, 13e	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243149&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118086577	376221537							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489658	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C34H34N4O4/c1-21-13-14-25-9-5-6-10-27(25)28(21)19-37-30-11-7-8-12-31(30)38(20-29(34(37)42)36-32(40)22(2)35-4)33(41)26-17-15-24(16-18-26)23(3)39/h5-18,22,29,35H,19-20H2,1-4H3,(H,36,40)/t22-,29-/m0/s1	FPRVCZFEMZUZRG-ZTOMLWHTSA-N	243150	US10053431, 13f	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243150&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077058	376221538							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489660	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O	InChI=1S/C35H38N4O6/c1-21-15-16-23-11-7-8-12-25(23)26(21)19-38-28-13-9-10-14-29(28)39(20-27(35(38)42)37-33(40)22(2)36-3)34(41)24-17-30(43-4)32(45-6)31(18-24)44-5/h7-18,22,27,36H,19-20H2,1-6H3,(H,37,40)/t22-,27-/m0/s1	FKGOLBNZPGUDLK-CUNXSJBXSA-N	243151	US10053431, 13g	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243151&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077083	376221539							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489662	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28-/m0/s1	VBKYKJZFJATBDB-MMTVBGGISA-N	50441820	CHEMBL2436206::US10053431, 69l	E3 ubiquitin-protein ligase XIAP [241-356]			 39300					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441820&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711483	175454137		CHEMBL2436206				ZINC96285528	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489664	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC2CCCCC2)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H39BrN4O4/c1-21(35-2)32(40)36-27-20-37(31(39)17-22-9-5-4-6-10-22)28-11-7-8-12-29(28)38(33(27)41)19-26-25-15-14-24(34)18-23(25)13-16-30(26)42-3/h7-8,11-16,18,21-22,27,35H,4-6,9-10,17,19-20H2,1-3H3,(H,36,40)/t21-,27-/m0/s1	HOWYCYQWHUQOKN-IDISGSTGSA-N	243153	US10053431, 13i	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243153&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076592	376221541							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489666	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(=O)C(C)(C)C)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C37H39BrN4O5/c1-22(39-5)34(44)40-29-21-42(35(45)24-13-11-23(12-14-24)33(43)37(2,3)4)31-10-8-7-9-30(31)41(36(29)46)20-28-27-17-16-26(38)19-25(27)15-18-32(28)47-6/h7-19,22,29,39H,20-21H2,1-6H3,(H,40,44)/t22-,29-/m0/s1	MUQICRLQVBPRHX-ZTOMLWHTSA-N	243154	US10053431, 13j	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243154&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076815	376221542							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489668	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(O)(O)C(F)(F)F)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H32BrF3N4O6/c1-19(39-2)30(43)40-26-18-42(31(44)20-8-11-22(12-9-20)33(46,47)34(36,37)38)28-7-5-4-6-27(28)41(32(26)45)17-25-24-14-13-23(35)16-21(24)10-15-29(25)48-3/h4-16,19,26,39,46-47H,17-18H2,1-3H3,(H,40,43)/t19-,26-/m0/s1	IWJPRIOMVNDBCD-SIBVEZHUSA-N	243155	US10053431, 13k	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243155&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076878	376221543							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489670	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2cccc(c2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)24-9-7-8-22(16-24)21(2)40)30-11-6-5-10-29(30)38(34(28)43)18-27-26-14-13-25(35)17-23(26)12-15-31(27)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28-/m0/s1	IVEUPPZQAPDURZ-MMTVBGGISA-N	243156	US10053431, 13l	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243156&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076580	376221544							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489672	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)[N+]([O-])=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C32H30BrN5O6/c1-19(34-2)30(39)35-26-18-37(31(40)20-8-12-23(13-9-20)38(42)43)28-7-5-4-6-27(28)36(32(26)41)17-25-24-14-11-22(33)16-21(24)10-15-29(25)44-3/h4-16,19,26,34H,17-18H2,1-3H3,(H,35,39)/t19-,26-/m0/s1	MPBAYUHXOUYQBZ-SIBVEZHUSA-N	50441812	CHEMBL2436207::US10053431, 13m	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441812&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711485	175454129		CHEMBL2436207				ZINC96285520	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489674	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCC[N+]([O-])=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C29H32BrN5O6/c1-18(31-2)28(37)32-23-17-33(27(36)9-6-14-35(39)40)24-7-4-5-8-25(24)34(29(23)38)16-22-21-12-11-20(30)15-19(21)10-13-26(22)41-3/h4-5,7-8,10-13,15,18,23,31H,6,9,14,16-17H2,1-3H3,(H,32,37)/t18-,23-/m0/s1	QJQMISPLQCHSJK-MBSDFSHPSA-N	243158	US10053431, 13n	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243158&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076613	376221545							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489676	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C35H35BrN4O5/c1-21(37-3)34(43)38-29-20-39(33(42)17-23-9-11-24(12-10-23)22(2)41)30-7-5-6-8-31(30)40(35(29)44)19-28-27-15-14-26(36)18-25(27)13-16-32(28)45-4/h5-16,18,21,29,37H,17,19-20H2,1-4H3,(H,38,43)/t21-,29-/m0/s1	XMPOAIGUDMFLDI-LGGPFLRQSA-N	243159	US10053431, 13o	E3 ubiquitin-protein ligase XIAP [241-356]			 22040					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243159&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076843	376221546							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489678	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C#N)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C33H30BrN5O4/c1-20(36-2)31(40)37-27-19-39(32(41)22-10-8-21(17-35)9-11-22)29-7-5-4-6-28(29)38(33(27)42)18-26-25-14-13-24(34)16-23(25)12-15-30(26)43-3/h4-16,20,27,36H,18-19H2,1-3H3,(H,37,40)/t20-,27-/m0/s1	QIVSDYYFNPWSEF-DCFHFQCYSA-N	243109	(2S)—N-[(3S)-5-[[6-bromo-2-(trideuteriomethoxy)-1-naphthyl]methyl]-1-(4-cyanobenzoyl)-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-2-(methylamino)propanamide hydrochloride::US10053431, 13p::US10053431, 84	E3 ubiquitin-protein ligase XIAP [241-356]			 42780					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243109&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076961	376221497							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489680	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CC23CC4CC(CC(C4)C2)C3)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C37H43BrN4O4/c1-22(39-2)35(44)40-30-21-41(34(43)19-37-16-23-12-24(17-37)14-25(13-23)18-37)31-6-4-5-7-32(31)42(36(30)45)20-29-28-10-9-27(38)15-26(28)8-11-33(29)46-3/h4-11,15,22-25,30,39H,12-14,16-21H2,1-3H3,(H,40,44)/t22-,23?,24?,25?,30-,37?/m0/s1	VJWPAPXXAYSAMG-CCDDUJHJSA-N	243161	US10053431, 13q	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243161&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076947	376221547							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489682	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCNC(=O)OCC2c3ccccc3-c3ccccc23)c2ccccc2N(Cc2c(OC)ccc3cc(ccc23)C(=O)OC)C1=O	InChI=1S/C45H45N5O8/c1-27(46-2)42(52)48-37-25-49(41(51)21-22-47-45(55)58-26-36-33-13-7-5-11-31(33)32-12-6-8-14-34(32)36)38-15-9-10-16-39(38)50(43(37)53)24-35-30-19-17-29(44(54)57-4)23-28(30)18-20-40(35)56-3/h5-20,23,27,36-37,46H,21-22,24-26H2,1-4H3,(H,47,55)(H,48,52)/t27-,37-/m0/s1	GWKUSTCKPNGPPM-ZSQPVGNWSA-N	243162	US10053431, 13r	E3 ubiquitin-protein ligase XIAP [241-356]			 46730					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243162&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077404	376221548							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489684	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C34H32F2N4O5/c1-20(37-3)31(42)38-27-19-40(32(43)24-14-12-22(13-15-24)21(2)41)29-11-7-6-10-28(29)39(33(27)44)18-26-25-9-5-4-8-23(25)16-17-30(26)45-34(35)36/h4-17,20,27,34,37H,18-19H2,1-3H3,(H,38,42)/t20-,27-/m0/s1	KWNFZHZGDAFIFB-DCFHFQCYSA-N	243163	US10053431, 69b::US10053431, 69n	E3 ubiquitin-protein ligase XIAP [241-356]			 46570					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243163&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076623	376221549							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489686	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2cc(=O)oc3cc(OC)ccc23)C1=O	InChI=1S/C33H32N4O7/c1-19(34-3)31(40)35-26-18-37(32(41)22-11-9-21(10-12-22)20(2)38)28-8-6-5-7-27(28)36(33(26)42)17-23-15-30(39)44-29-16-24(43-4)13-14-25(23)29/h5-16,19,26,34H,17-18H2,1-4H3,(H,35,40)/t19-,26-/m0/s1	OKXQCWANIDVLSR-SIBVEZHUSA-N	243164	US10053431, 69c	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243164&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076915	376221550							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489688	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2noc3ccccc23)C1=O	InChI=1S/C30H29N5O5/c1-18(31-3)28(37)32-24-17-34(29(38)21-14-12-20(13-15-21)19(2)36)25-9-5-6-10-26(25)35(30(24)39)16-23-22-8-4-7-11-27(22)40-33-23/h4-15,18,24,31H,16-17H2,1-3H3,(H,32,37)/t18-,24-/m0/s1	CWPDYSFTIMRFCO-UUOWRZLLSA-N	243165	US10053431, 69d	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243165&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077234	376221551							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489690	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2noc3cc(Br)ccc23)C1=O	InChI=1S/C30H28BrN5O5/c1-17(32-3)28(38)33-24-16-35(29(39)20-10-8-19(9-11-20)18(2)37)25-6-4-5-7-26(25)36(30(24)40)15-23-22-13-12-21(31)14-27(22)41-34-23/h4-14,17,24,32H,15-16H2,1-3H3,(H,33,38)/t17-,24-/m0/s1	VVIQSBJMQJDHMV-XDHUDOTRSA-N	243166	US10053431, 69e	E3 ubiquitin-protein ligase XIAP [241-356]			 50300					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243166&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077208	376221552							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489692	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3c(Br)cccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-14-12-22(13-15-23)21(2)40)30-11-6-5-10-29(30)38(34(28)43)18-26-24-8-7-9-27(35)25(24)16-17-31(26)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28-/m0/s1	FCBDCRIHHVUGDE-MMTVBGGISA-N	243167	US10053431, 69f::US10053431, 69m	E3 ubiquitin-protein ligase XIAP [241-356]			 30650					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243167&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077140	376221553							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489694	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3ccccc23)C1=O	InChI=1S/C34H34N4O5/c1-21(35-3)32(40)36-28-20-38(33(41)25-15-13-23(14-16-25)22(2)39)30-12-8-7-11-29(30)37(34(28)42)19-27-26-10-6-5-9-24(26)17-18-31(27)43-4/h5-18,21,28,35H,19-20H2,1-4H3,(H,36,40)/t21-,28-/m0/s1	FXHJEMSCMLSORJ-KMRXNPHXSA-N	243168	US10053431, 69g	E3 ubiquitin-protein ligase XIAP [241-356]			 42520					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243168&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077263	376221554							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489696	C[C@H](N)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OCC(F)(F)F)ccc3ccccc23)C1=O	InChI=1S/C34H31F3N4O5/c1-20(38)31(43)39-27-18-41(32(44)24-13-11-22(12-14-24)21(2)42)29-10-6-5-9-28(29)40(33(27)45)17-26-25-8-4-3-7-23(25)15-16-30(26)46-19-34(35,36)37/h3-16,20,27H,17-19,38H2,1-2H3,(H,39,43)/t20-,27-/m0/s1	PCLCZNAVFJDVBZ-DCFHFQCYSA-N	243169	US10053431, 69h	E3 ubiquitin-protein ligase XIAP [241-356]			 30310					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243169&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076800	376221555					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489698	C[C@H](N)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC(F)F)ccc3ccccc23)C1=O	InChI=1S/C33H30F2N4O5/c1-19(36)30(41)37-26-18-39(31(42)23-13-11-21(12-14-23)20(2)40)28-10-6-5-9-27(28)38(32(26)43)17-25-24-8-4-3-7-22(24)15-16-29(25)44-33(34)35/h3-16,19,26,33H,17-18,36H2,1-2H3,(H,37,41)/t19-,26-/m0/s1	RDBLJXAPGCYLSN-SIBVEZHUSA-N	243170	US10053431, 69i	E3 ubiquitin-protein ligase XIAP [241-356]			 51970					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243170&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118077356	376221556					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489700	COc1ccc2c(CN3c4ccccc4N(C[C@H](NC(=O)[C@H](C)N)C3=O)C(=O)c3ccc(cc3)C(C)=O)cc(=O)oc2c1	InChI=1S/C32H30N4O7/c1-18(33)30(39)34-25-17-36(31(40)21-10-8-20(9-11-21)19(2)37)27-7-5-4-6-26(27)35(32(25)41)16-22-14-29(38)43-28-15-23(42-3)12-13-24(22)28/h4-15,18,25H,16-17,33H2,1-3H3,(H,34,39)/t18-,25-/m0/s1	HVVSZNGOPOXPIZ-BVZFJXPGSA-N	243171	US10053431, 69j	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243171&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076759	376221557					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489702	C[C@H](N)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2noc3ccccc23)C1=O	InChI=1S/C29H27N5O5/c1-17(30)27(36)31-23-16-33(28(37)20-13-11-19(12-14-20)18(2)35)24-8-4-5-9-25(24)34(29(23)38)15-22-21-7-3-6-10-26(21)39-32-22/h3-14,17,23H,15-16,30H2,1-2H3,(H,31,36)/t17-,23-/m0/s1	BAOXXIQWSSOARZ-SBUREZEXSA-N	243172	US10053431, 69k	E3 ubiquitin-protein ligase XIAP [241-356]			>54800					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=243172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=243172&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118076682	376221558					C03803		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
489704	CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(cc2)C(C)=O)c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O	InChI=1S/C34H33BrN4O5/c1-20(36-3)32(41)37-28-19-39(33(42)23-11-9-22(10-12-23)21(2)40)30-8-6-5-7-29(30)38(34(28)43)18-27-26-15-14-25(35)17-24(26)13-16-31(27)44-4/h5-17,20,28,36H,18-19H2,1-4H3,(H,37,41)/t20-,28-/m0/s1	VBKYKJZFJATBDB-MMTVBGGISA-N	50441820	CHEMBL2436206::US10053431, 69l	E3 ubiquitin-protein ligase XIAP [241-356]			 41510					7.5	25.00 C	US Patent		10.7270/Q2W097X3		aid1795150	US10053431	Chen, S; Donnell, AF; Kester, RF; Le, K; Lou, Y; Michoud, C; Remiszewski, S; Rupert, KC; Weisel, M	Hoffmann-La Roche Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441820&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			72711483	175454137		CHEMBL2436206				ZINC96285528	1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783001	CN[C@@H](C)C(=O)N[C@H]1CCO[C@@H]2N(C(C(=O)N[C@@H]3CCCc4ccccc34)c3ccccc23)C1=O	InChI=1S/C27H32N4O4/c1-16(28-2)24(32)30-22-14-15-35-27-20-12-6-5-11-19(20)23(31(27)26(22)34)25(33)29-21-13-7-9-17-8-3-4-10-18(17)21/h3-6,8,10-12,16,21-23,27-28H,7,9,13-15H2,1-2H3,(H,29,33)(H,30,32)/t16-,21+,22-,23?,27-/m0/s1	SRRKQOXMYDWYGT-MVCZWWRHSA-N	391804	US10300074, Product 17a::US11111270, Compound 27	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391804&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201950	404960168							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783004	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C25H36N4O4/c1-15(26-4)22(30)28-19-12-13-33-20-14-25(2,3)21(29(20)24(19)32)23(31)27-18-11-7-9-16-8-5-6-10-17(16)18/h5-6,8,10,15,18-21,26H,7,9,11-14H2,1-4H3,(H,27,31)(H,28,30)/t15-,18+,19-,20-,21?/m0/s1	PBGOFGSVVXGJCA-DUDGCXMLSA-N	391805	US10300074, Product 17b	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391805&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118478152	404960169							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783007	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C25H36N4O3S/c1-15(26-4)22(30)28-19-12-13-33-20-14-25(2,3)21(29(20)24(19)32)23(31)27-18-11-7-9-16-8-5-6-10-17(16)18/h5-6,8,10,15,18-21,26H,7,9,11-14H2,1-4H3,(H,27,31)(H,28,30)/t15-,18+,19-,20-,21?/m0/s1	IIXXVAXNYFQXST-DUDGCXMLSA-N	391806	US10300074, Product 17c::US11111270, Compound 35	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391806&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			74538665	404960170							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783010	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(OC)cc1	InChI=1S/C19H26N4O5/c1-11(20-2)17(24)22-14-10-28-16-9-8-15(23(16)19(14)26)18(25)21-12-4-6-13(27-3)7-5-12/h4-7,11,14-16,20H,8-10H2,1-3H3,(H,21,25)(H,22,24)/t11-,14-,15?,16-/m0/s1	NBMUDTIUNPDSAM-OLSVDGPUSA-N	391807	US10300074, Compd 3::US10300074, Compd 4::US10300074, Compd 7::US11111270, Compound 7	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391807&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201990	404960171							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783012	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(OC)cc1	InChI=1S/C19H26N4O5/c1-11(20-2)17(24)22-14-10-28-16-9-8-15(23(16)19(14)26)18(25)21-12-4-6-13(27-3)7-5-12/h4-7,11,14-16,20H,8-10H2,1-3H3,(H,21,25)(H,22,24)/t11-,14-,15?,16-/m0/s1	NBMUDTIUNPDSAM-OLSVDGPUSA-N	391807	US10300074, Compd 3::US10300074, Compd 4::US10300074, Compd 7::US11111270, Compound 7	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391807&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201990	404960171							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783014	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)NCc1ccccc1	InChI=1S/C19H26N4O4/c1-12(20-2)17(24)22-14-11-27-16-9-8-15(23(16)19(14)26)18(25)21-10-13-6-4-3-5-7-13/h3-7,12,14-16,20H,8-11H2,1-2H3,(H,21,25)(H,22,24)/t12-,14-,15?,16-/m0/s1	JVKFFBGNOJIZCH-IIQYYHDJSA-N	391809	US10300074, Compd 5::US10300074, Compd 6::US11111270, Compound 6	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391809&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90190770	404960172							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783016	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)NCc1ccccc1	InChI=1S/C19H26N4O4/c1-12(20-2)17(24)22-14-11-27-16-9-8-15(23(16)19(14)26)18(25)21-10-13-6-4-3-5-7-13/h3-7,12,14-16,20H,8-11H2,1-2H3,(H,21,25)(H,22,24)/t12-,14-,15?,16-/m0/s1	JVKFFBGNOJIZCH-IIQYYHDJSA-N	391809	US10300074, Compd 5::US10300074, Compd 6::US11111270, Compound 6	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391809&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90190770	404960172							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783018	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(OC)cc1	InChI=1S/C19H26N4O5/c1-11(20-2)17(24)22-14-10-28-16-9-8-15(23(16)19(14)26)18(25)21-12-4-6-13(27-3)7-5-12/h4-7,11,14-16,20H,8-10H2,1-3H3,(H,21,25)(H,22,24)/t11-,14-,15?,16-/m0/s1	NBMUDTIUNPDSAM-OLSVDGPUSA-N	391807	US10300074, Compd 3::US10300074, Compd 4::US10300074, Compd 7::US11111270, Compound 7	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391807&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201990	404960171							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783020	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(Cl)cc1	InChI=1S/C18H23ClN4O4/c1-10(20-2)16(24)22-13-9-27-15-8-7-14(23(15)18(13)26)17(25)21-12-5-3-11(19)4-6-12/h3-6,10,13-15,20H,7-9H2,1-2H3,(H,21,25)(H,22,24)/t10-,13-,14?,15-/m0/s1	CMRJIHMIAAPULE-LGEGPZQVSA-N	391812	US10300074, Compd 8::US11111270, Compound 8	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391812&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90190855	404960173							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783022	CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)NC1CCCc2ccccc12	InChI=1S/C22H30N4O4/c1-13(23-2)20(27)25-17-12-30-19-11-10-18(26(19)22(17)29)21(28)24-16-9-5-7-14-6-3-4-8-15(14)16/h3-4,6,8,13,16-19,23H,5,7,9-12H2,1-2H3,(H,24,28)(H,25,27)/t13-,16?,17-,18?,19-/m0/s1	IJPZPWFXNFKMBF-LFQJEHLWSA-N	391813	US10300074, Compd 9::US11111270, Compound 9	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391813&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			126712467	404960174							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783024	CN[C@@H](C)C(=O)N[C@H]1[C@@H](C)O[C@H]2CCC(N2C1=O)C(=O)NC1CCCc2ccccc12	InChI=1S/C23H32N4O4/c1-13(24-3)21(28)26-20-14(2)31-19-12-11-18(27(19)23(20)30)22(29)25-17-10-6-8-15-7-4-5-9-16(15)17/h4-5,7,9,13-14,17-20,24H,6,8,10-12H2,1-3H3,(H,25,29)(H,26,28)/t13-,14+,17?,18?,19-,20-/m0/s1	MPNOJWOXEWYDRH-ATCZTYQISA-N	391814	US10300074, Compd 10::US11111270, Compound 10	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391814&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			129903698	404960175							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783027	CN[C@@H](C)C(=O)N[C@H]1[C@@H](C)O[C@H]2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12	InChI=1S/C23H28N4O4/c1-13(24-3)21(28)26-20-14(2)31-19-12-11-18(27(19)23(20)30)22(29)25-17-10-6-8-15-7-4-5-9-16(15)17/h4-10,13-14,18-20,24H,11-12H2,1-3H3,(H,25,29)(H,26,28)/t13-,14+,18?,19-,20-/m0/s1	RZJDMCUSSGJZOI-FVVJRULNSA-N	391815	US10300074, Compd 11::US11111270, Compound 11	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391815&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90190669	404960176							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783029	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O4/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19?,20-/m0/s1	DGUZQZXTUHDVHK-JVYSIHQFSA-N	391816	US10300074, Compd 12::US11111270, Compound 12	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391816&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071233	404960177							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783032	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12	InChI=1S/C23H28N4O4/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-9,14,18-20,24H,10-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,18-,19?,20-/m0/s1	XTWCHYNJYPOFBR-ZHHPSBPMSA-N	391817	US10300074, Compd 13	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391817&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071350	404960178							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783034	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1	InChI=1S/C26H32N4O4/c1-17(27-2)24(31)28-20-15-16-34-22-14-13-21(30(22)26(20)33)25(32)29-23(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17,20-23,27H,13-16H2,1-2H3,(H,28,31)(H,29,32)/t17-,20-,21?,22-/m0/s1	KOGGGAUQFHJPPH-ABQJZZKHSA-N	391819	US10300074, Compd 14::US11111270, Compound 14	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391819&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071348	404960180							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783037	CN[C@@H](C)C(=O)N[C@H]1[C@@H](C)O[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1	InChI=1S/C26H32N4O4/c1-16(27-3)24(31)28-22-17(2)34-21-15-14-20(30(21)26(22)33)25(32)29-23(18-10-6-4-7-11-18)19-12-8-5-9-13-19/h4-13,16-17,20-23,27H,14-15H2,1-3H3,(H,28,31)(H,29,32)/t16-,17+,20?,21-,22-/m0/s1	JTUKOFSAWIHEHS-HNYVQNJRSA-N	391820	US10300074, Compd 15::US11111270, Compound 15	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391820&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201968	404960181							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783039	CN[C@@H](C)C(=O)N[C@H]1CCCNC2CCC(N2C1=O)C(=O)NC1CCCc2ccccc12	InChI=1S/C24H35N5O3/c1-15(25-2)22(30)28-19-11-6-14-26-21-13-12-20(29(21)24(19)32)23(31)27-18-10-5-8-16-7-3-4-9-17(16)18/h3-4,7,9,15,18-21,25-26H,5-6,8,10-14H2,1-2H3,(H,27,31)(H,28,30)/t15-,18?,19-,20?,21?/m0/s1	RYBZPXRGSOWIAP-KDMVFVGQSA-N	391821	US10300074, Compd 16	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391821&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			126712469	404960182							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783041	CN[C@@H](C)C(=O)N[C@H]1CCCNC2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12	InChI=1S/C24H31N5O3/c1-15(25-2)22(30)28-19-11-6-14-26-21-13-12-20(29(21)24(19)32)23(31)27-18-10-5-8-16-7-3-4-9-17(16)18/h3-5,7-10,15,19-21,25-26H,6,11-14H2,1-2H3,(H,27,31)(H,28,30)/t15-,19-,20?,21?/m0/s1	SGCOICSZDJXTOO-SGRCFUTNSA-N	391822	US10300074, Compd 17	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391822&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201999	404960183							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783043	C[C@H](N(C)C(C)=O)C(=O)N[C@H]1CCCN([C@H]2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12)C(C)=O	InChI=1S/C28H35N5O5/c1-17(31(4)18(2)34)26(36)30-23-13-8-16-32(19(3)35)25-15-14-24(33(25)28(23)38)27(37)29-22-12-7-10-20-9-5-6-11-21(20)22/h5-7,9-12,17,23-25H,8,13-16H2,1-4H3,(H,29,37)(H,30,36)/t17-,23-,24?,25+/m0/s1	ILMZGDJBGWZLET-LMJNJGBBSA-N	391823	US10300074, Compd 18::US10300074, Compd 19	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391823&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201960	404960184							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783045	C[C@H](N(C)C(C)=O)C(=O)N[C@H]1CCCN([C@H]2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12)C(C)=O	InChI=1S/C28H35N5O5/c1-17(31(4)18(2)34)26(36)30-23-13-8-16-32(19(3)35)25-15-14-24(33(25)28(23)38)27(37)29-22-12-7-10-20-9-5-6-11-21(20)22/h5-7,9-12,17,23-25H,8,13-16H2,1-4H3,(H,29,37)(H,30,36)/t17-,23-,24?,25+/m0/s1	ILMZGDJBGWZLET-LMJNJGBBSA-N	391823	US10300074, Compd 18::US10300074, Compd 19	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391823&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201960	404960184							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783047	CN[C@@H](C)C(=O)N[C@H]1CCCN(C2CCC(N2C1=O)C(=O)NC1CCCc2ccccc12)C(C)=O	InChI=1S/C26H37N5O4/c1-16(27-3)24(33)29-21-12-7-15-30(17(2)32)23-14-13-22(31(23)26(21)35)25(34)28-20-11-6-9-18-8-4-5-10-19(18)20/h4-5,8,10,16,20-23,27H,6-7,9,11-15H2,1-3H3,(H,28,34)(H,29,33)/t16-,20?,21-,22?,23?/m0/s1	GQKHBNWZSAKNGT-MXZRMRQCSA-N	391825	US10300074, Compd 20::US10300074, Compd 21	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391825&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			130223019	404960185							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783049	CN[C@@H](C)C(=O)N[C@H]1CCCN(C2CCC(N2C1=O)C(=O)NC1CCCc2ccccc12)C(C)=O	InChI=1S/C26H37N5O4/c1-16(27-3)24(33)29-21-12-7-15-30(17(2)32)23-14-13-22(31(23)26(21)35)25(34)28-20-11-6-9-18-8-4-5-10-19(18)20/h4-5,8,10,16,20-23,27H,6-7,9,11-15H2,1-3H3,(H,28,34)(H,29,33)/t16-,20?,21-,22?,23?/m0/s1	GQKHBNWZSAKNGT-MXZRMRQCSA-N	391825	US10300074, Compd 20::US10300074, Compd 21	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391825&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			130223019	404960185							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783051	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CCC(N2C1=O)C(=O)n1ccc2ccccc12	InChI=1S/C21H26N4O4/c1-13(22-2)19(26)23-15-10-12-29-18-8-7-17(25(18)20(15)27)21(28)24-11-9-14-5-3-4-6-16(14)24/h3-6,9,11,13,15,17-18,22H,7-8,10,12H2,1-2H3,(H,23,26)/t13-,15-,17?,18-/m0/s1	MVTULAMVOISCBR-FDGRXGLPSA-N	391827	US10300074, Compd 22::US10300074, Compd 23	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391827&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			130222442	404960186							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783053	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CCC(N2C1=O)C(=O)n1ccc2ccccc12	InChI=1S/C21H26N4O4/c1-13(22-2)19(26)23-15-10-12-29-18-8-7-17(25(18)20(15)27)21(28)24-11-9-14-5-3-4-6-16(14)24/h3-6,9,11,13,15,17-18,22H,7-8,10,12H2,1-2H3,(H,23,26)/t13-,15-,17?,18-/m0/s1	MVTULAMVOISCBR-FDGRXGLPSA-N	391827	US10300074, Compd 22::US10300074, Compd 23	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391827&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			130222442	404960186							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783055	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O3S/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19?,20-/m0/s1	GRPYHMFJRWZUEE-JVYSIHQFSA-N	391829	US10300074, Compd 24	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391829&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071234	404960187							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783058	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC[C@H](N2C1=O)C(=O)Nc1cccc2ccccc12	InChI=1S/C23H28N4O4/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-9,14,18-20,24H,10-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,18-,19-,20-/m0/s1	XTWCHYNJYPOFBR-DSYPUSFNSA-N	391830	US10300074, Compd 25::US11111270, Compound 25	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391830&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201949	404960188							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783060	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC(C)(C)[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C25H36N4O4/c1-15(26-4)22(30)28-19-12-13-33-20-14-25(2,3)21(29(20)24(19)32)23(31)27-18-11-7-9-16-8-5-6-10-17(16)18/h5-6,8,10,15,18-21,26H,7,9,11-14H2,1-4H3,(H,27,31)(H,28,30)/t15-,18+,19-,20-,21+/m0/s1	PBGOFGSVVXGJCA-KDJJVYBXSA-N	391831	US10300074, Compd 26::US11111270, Compound 26	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391831&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071591	404960189							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783063	CN[C@@H](C)C(=O)N[C@H]1CCO[C@@H]2N(C(C(=O)N[C@@H]3CCCc4ccccc34)c3ccccc23)C1=O	InChI=1S/C27H32N4O4/c1-16(28-2)24(32)30-22-14-15-35-27-20-12-6-5-11-19(20)23(31(27)26(22)34)25(33)29-21-13-7-9-17-8-3-4-10-18(17)21/h3-6,8,10-12,16,21-23,27-28H,7,9,13-15H2,1-2H3,(H,29,33)(H,30,32)/t16-,21+,22-,23?,27-/m0/s1	SRRKQOXMYDWYGT-MVCZWWRHSA-N	391832	US10300074, Compd 27	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391832&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201950	404960190							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783066	CN[C@@H](C)C(=O)N[C@H]1CCN[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H33N5O3/c1-14(24-2)21(29)27-18-12-13-25-20-11-10-19(28(20)23(18)31)22(30)26-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24-25H,5,7,9-13H2,1-2H3,(H,26,30)(H,27,29)/t14-,17+,18-,19?,20+/m0/s1	YYQVMLJSZUXZFS-LREMNVJNSA-N	391833	US10300074, Compd 28::US10300074, Compd 29	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391833&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071474	404960191							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783068	CN[C@@H](C)C(=O)N[C@H]1CCN[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H33N5O3/c1-14(24-2)21(29)27-18-12-13-25-20-11-10-19(28(20)23(18)31)22(30)26-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24-25H,5,7,9-13H2,1-2H3,(H,26,30)(H,27,29)/t14-,17+,18-,19?,20+/m0/s1	YYQVMLJSZUXZFS-LREMNVJNSA-N	391833	US10300074, Compd 28::US10300074, Compd 29	E3 ubiquitin-protein ligase XIAP [241-356]		>50000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391833&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071474	404960191							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783070	CN[C@@H](C)C(=O)N[C@H]1Cc2c([nH]c3ccccc23)[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12			391835	US10300074, Compd 30::US10300074, Compd 31::US11111270, Compound 31	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391835&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071349	404960192							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783072	CN[C@@H](C)C(=O)N[C@H]1Cc2c([nH]c3ccccc23)[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12			391835	US10300074, Compd 30::US10300074, Compd 31::US11111270, Compound 31	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391835&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071349	404960192							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783074	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H]1CCOc2ccccc12	InChI=1S/C22H30N4O5/c1-13(23-2)20(27)25-16-10-12-31-19-8-7-17(26(19)22(16)29)21(28)24-15-9-11-30-18-6-4-3-5-14(15)18/h3-6,13,15-17,19,23H,7-12H2,1-2H3,(H,24,28)(H,25,27)/t13-,15+,16-,17-,19-/m0/s1	FOZRDSOEUULRIC-CICISYLWSA-N	391837	US10300074, Compd 32::US11111270, Compound 32	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391837&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201954	404960193							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783077	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O4/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19-,20-/m0/s1	DGUZQZXTUHDVHK-IQOMPXODSA-N	391838	US10300074, Compd 33::US11111270, Compound 33	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391838&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071472	404960194							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783080	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O3S/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19-,20-/m0/s1	GRPYHMFJRWZUEE-IQOMPXODSA-N	391839	US10300074, Compd 34::US11111270, Compound 34	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391839&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071475	404960195							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783083	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C25H36N4O3S/c1-15(26-4)22(30)28-19-12-13-33-20-14-25(2,3)21(29(20)24(19)32)23(31)27-18-11-7-9-16-8-5-6-10-17(16)18/h5-6,8,10,15,18-21,26H,7,9,11-14H2,1-4H3,(H,27,31)(H,28,30)/t15-,18+,19-,20-,21?/m0/s1	IIXXVAXNYFQXST-DUDGCXMLSA-N	391840	US10300074, Compd 35	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391840&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			74538665	404960196							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783086	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CC[C@@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O3S/c1-14(24-2)21(28)26-18-12-13-31-20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19+,20-/m0/s1	GRPYHMFJRWZUEE-AXBXVSCFSA-N	391841	US10300074, Compd 36::US11111270, Compound 36	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391841&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071352	404960197							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783089	CN[C@@H](C)C(=O)N[C@H]1CCS(=O)(=O)[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O5S/c1-14(24-2)21(28)26-18-12-13-33(31,32)20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19-,20-/m0/s1	NQKSLNVTSSRSHW-IQOMPXODSA-N	391842	US10300074, Compd 37::US11111270, Compound 37	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391842&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071476	404960198							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783091	CN[C@@H](C)C(=O)N[C@H]1CCS(=O)(=O)[C@H]2CC[C@@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C23H32N4O5S/c1-14(24-2)21(28)26-18-12-13-33(31,32)20-11-10-19(27(20)23(18)30)22(29)25-17-9-5-7-15-6-3-4-8-16(15)17/h3-4,6,8,14,17-20,24H,5,7,9-13H2,1-2H3,(H,25,29)(H,26,28)/t14-,17+,18-,19+,20-/m0/s1	NQKSLNVTSSRSHW-AXBXVSCFSA-N	391843	US10300074, Compd 38::US11111270, Compound 38	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391843&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071471	404960199							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783093	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC[C@@H](N2C1=O)C(=O)N[C@@H]1CCOc2ccccc12	InChI=1S/C22H30N4O5/c1-13(23-2)20(27)25-16-10-12-31-19-8-7-17(26(19)22(16)29)21(28)24-15-9-11-30-18-6-4-3-5-14(15)18/h3-6,13,15-17,19,23H,7-12H2,1-2H3,(H,24,28)(H,25,27)/t13-,15+,16-,17+,19-/m0/s1	FOZRDSOEUULRIC-BJZZIADLSA-N	391844	US10300074, Compd 39::US11111270, Compound 39	E3 ubiquitin-protein ligase XIAP [241-356]		 37500								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391844&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201941	404960200							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783095	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC(C)(C)C(N2C1=O)C(=O)Nc1ccccc1SSc1ccccc1NC(=O)C1N2[C@H](CC1(C)C)OCC[C@H](NC(=O)[C@H](C)NC)C2=O	InChI=1S/C42H58N8O8S2/c1-23(43-7)35(51)47-27-17-19-57-31-21-41(3,4)33(49(31)39(27)55)37(53)45-25-13-9-11-15-29(25)59-60-30-16-12-10-14-26(30)46-38(54)34-42(5,6)22-32-50(34)40(56)28(18-20-58-32)48-36(52)24(2)44-8/h9-16,23-24,27-28,31-34,43-44H,17-22H2,1-8H3,(H,45,53)(H,46,54)(H,47,51)(H,48,52)/t23-,24-,27-,28-,31-,32-,33?,34?/m0/s1	AIFGCTVCICYJCY-PZMKEKQBSA-N	391845	US10300074, Compd 40	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391845&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118467932	404960201					C15496		1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783097	CN[C@@H](C)C(=O)N[C@H]1CCS[C@H]2CCCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C24H34N4O3S/c1-15(25-2)22(29)27-19-13-14-32-21-12-6-11-20(28(21)24(19)31)23(30)26-18-10-5-8-16-7-3-4-9-17(16)18/h3-4,7,9,15,18-21,25H,5-6,8,10-14H2,1-2H3,(H,26,30)(H,27,29)/t15-,18+,19-,20?,21-/m0/s1	FWUVYMSKIZICRV-ADURKJLDSA-N	391846	US10300074, Compd 41	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391846&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			90201642	404960202							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783099	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC3(CC=CC3)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C27H36N4O4/c1-17(28-2)24(32)30-21-12-15-35-22-16-27(13-5-6-14-27)23(31(22)26(21)34)25(33)29-20-11-7-9-18-8-3-4-10-19(18)20/h3-6,8,10,17,20-23,28H,7,9,11-16H2,1-2H3,(H,29,33)(H,30,32)/t17-,20+,21-,22-,23?/m0/s1	RSJCHSVTXILJJN-CFLMPHEOSA-N	391847	US10300074, Compd 42	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391847&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071592	404960203							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783102	CN[C@@H](C)C(=O)N[C@H]1CCO[C@H]2CC3(CCCC3)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C27H38N4O4/c1-17(28-2)24(32)30-21-12-15-35-22-16-27(13-5-6-14-27)23(31(22)26(21)34)25(33)29-20-11-7-9-18-8-3-4-10-19(18)20/h3-4,8,10,17,20-23,28H,5-7,9,11-16H2,1-2H3,(H,29,33)(H,30,32)/t17-,20+,21-,22-,23?/m0/s1	OXRCNGFIXLNXEZ-CFLMPHEOSA-N	391848	US10300074, Compd 43	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391848&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			76071593	404960204							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783104	CN[C@@H](C)C(=O)N[C@H]1Cc2cc(O)c(O)cc2[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C30H38N4O5/c1-16(31-4)27(37)33-22-12-18-13-24(35)25(36)14-20(18)23-15-30(2,3)26(34(23)29(22)39)28(38)32-21-11-7-9-17-8-5-6-10-19(17)21/h5-6,8,10,13-14,16,21-23,26,31,35-36H,7,9,11-12,15H2,1-4H3,(H,32,38)(H,33,37)/t16-,21+,22-,23+,26?/m0/s1	RQJNKFQYBQNZKM-VNTVSQQUSA-N	391849	US10300074, Compd 44	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391849&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118467941	404960205							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783107	CN[C@@H](C)C(=O)N[C@H]1Cc2ccc(O)cc2[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C30H38N4O4/c1-17(31-4)27(36)33-24-14-19-12-13-20(35)15-22(19)25-16-30(2,3)26(34(25)29(24)38)28(37)32-23-11-7-9-18-8-5-6-10-21(18)23/h5-6,8,10,12-13,15,17,23-26,31,35H,7,9,11,14,16H2,1-4H3,(H,32,37)(H,33,36)/t17-,23+,24-,25+,26?/m0/s1	WWSXHSXXXOEQKI-UQFYKGKHSA-N	391850	US10300074, Compd 45	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391850&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118467925	404960206							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783109	CN[C@@H](C)C(=O)N[C@H]1CC(=O)N[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C25H35N5O4/c1-14(26-4)22(32)28-18-12-20(31)29-19-13-25(2,3)21(30(19)24(18)34)23(33)27-17-11-7-9-15-8-5-6-10-16(15)17/h5-6,8,10,14,17-19,21,26H,7,9,11-13H2,1-4H3,(H,27,33)(H,28,32)(H,29,31)/t14-,17+,18-,19+,21?/m0/s1	DWFJMDXUFGOBCU-OZWJTPLTSA-N	391851	US10300074, Compd 46::US11111270, Compound 46	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391851&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118467917	404960207							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
783112	CN[C@@H](C)C(=O)N[C@H]1Cc2cc(O)ccc2[C@H]2CC(C)(C)C(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12	InChI=1S/C30H38N4O4/c1-17(31-4)27(36)33-24-15-19-14-20(35)12-13-22(19)25-16-30(2,3)26(34(25)29(24)38)28(37)32-23-11-7-9-18-8-5-6-10-21(18)23/h5-6,8,10,12-14,17,23-26,31,35H,7,9,11,15-16H2,1-4H3,(H,32,37)(H,33,36)/t17-,23+,24-,25+,26?/m0/s1	VERWQRXAOGRLPX-UQFYKGKHSA-N	391852	US10300074, Compd 47	E3 ubiquitin-protein ligase XIAP [241-356]		<25000								US Patent		10.7270/Q25B04VG		aid1798879	US10300074	Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA	Sanford Burnham Prebys Medical Discovery Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=391852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=391852&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search			118467902	404960208							1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822118	C[C@@H]1CN(CC(=O)N2CC(C)(C(=O)NCCNC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C62H82F2N10O6/c1-41-31-71(51(29-67-41)33-69-21-23-79-37-43(69)3)35-57(75)73-39-61(5,53-17-11-47(27-55(53)73)25-45-7-13-49(63)14-8-45)59(77)65-19-20-66-60(78)62(6)40-74(56-28-48(12-18-54(56)62)26-46-9-15-50(64)16-10-46)58(76)36-72-32-42(2)68-30-52(72)34-70-22-24-80-38-44(70)4/h7-18,27-28,41-44,51-52,67-68H,19-26,29-40H2,1-6H3,(H,65,77)(H,66,78)/t41-,42-,43-,44-,51-,52-,61?,62?/m1/s1	VRGIZOAUSBZMJC-YTBOIHSISA-N	412164	US10398702, Example 3::tert-Butyl (2R,5S)-4-[2-[3-[2-[[1-[2-[(2S,5R)-4-tert-butoxycarbonyl-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]acetyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indoline-3-carbonyl]amino]ethylcarbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 3.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412164&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822134	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CC(=O)NCCCC3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C61H77F3N10O8/c1-37-31-72(46(30-67-37)33-71-22-25-82-35-38(71)2)34-54(77)74-36-61(4,48-17-12-41(27-51(48)74)26-40-10-14-44(62)15-11-40)20-7-21-66-52(75)29-53(76)68-45-16-13-43-32-73(57(47(43)28-45)59(79)70-56-49(63)8-6-9-50(56)64)60(80)55(42-18-23-81-24-19-42)69-58(78)39(3)65-5/h6,8-17,27-28,37-39,42,46,55,57,65,67H,7,18-26,29-36H2,1-5H3,(H,66,75)(H,68,76)(H,69,78)(H,70,79)/t37-,38-,39+,46-,55+,57+,61?/m1/s1	ZRZQYEMQDXBPFV-RNMKPMEYSA-N	412168	N1-((S)-3-((2,6- difluorophenyl)carbamoyl)-2- ((S)-2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetypisoindolin-5-yl)-N3- (3-(6-(4-fluorobenzyl)-3- methyl-1-(2-((2R,5R)-5- methyl-2(((R)-3- methylmorpholino)methyl) piperazin-1-yl)acetypindolin- 3-yl)propyl)malonamide trihydrochloride::US10398702, Example 7	E3 ubiquitin-protein ligase XIAP [241-356]			 26.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412168&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822138	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C58H71F3N10O8/c1-34-28-69(43(26-63-34)30-68-19-22-79-32-35(68)2)31-50(73)71-33-58(4,45-16-11-38(24-48(45)71)23-37-9-13-41(59)14-10-37)57(77)64-27-49(72)65-42-15-12-40-29-70(53(44(40)25-42)55(75)67-52-46(60)7-6-8-47(52)61)56(76)51(39-17-20-78-21-18-39)66-54(74)36(3)62-5/h6-16,24-25,34-36,39,43,51,53,62-63H,17-23,26-33H2,1-5H3,(H,64,77)(H,65,72)(H,66,74)(H,67,75)/t34-,35-,36+,43-,51+,53+,58-/m1/s1	HOKHIOIWTNNVMY-JHJKZRHASA-N	412169	(3S)-N-[2-[[(3S)-3-[(2,6- difluorophenyl)carbamoyl]- 2-[(2S)-2-[[(2S)-2- (methylamino)propanoyl] amino]-2-(oxan-4-yl)acetyl]- 1,3-dihydroisoindol-5- yl]amino]-2-oxoethyl]-6-[(4- fluorophenyl)methyl]-3- methyl-1-[2-[(2R,5R)-5- methyl-2-[[(3R)-3- methylmorpholin-4- yl]methyl]piperazin-1- yl]acetyl]-2H-indole-3- carboxamide;trihydrochloride::US10398702, Example 8	E3 ubiquitin-protein ligase XIAP [241-356]			 4.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412169&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822162	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cc(ccc1F)C(=O)NCCNC(=O)C1(C)CN(C(=O)CN2C[C@@H](C)NC[C@@H]2CN2CCOC[C@H]2C)c2cc(Cc3ccc(F)cc3)ccc12	InChI=1S/C59H74F2N10O8/c1-36-30-69(45(29-65-36)32-68-22-25-79-34-37(68)2)33-51(72)71-35-59(4,47-16-12-40(27-50(47)71)26-39-10-14-44(60)15-11-39)58(77)64-21-20-63-55(74)42-13-17-48(61)49(28-42)66-56(75)53-46-9-7-6-8-43(46)31-70(53)57(76)52(41-18-23-78-24-19-41)67-54(73)38(3)62-5/h6-17,27-28,36-38,41,45,52-53,62,65H,18-26,29-35H2,1-5H3,(H,63,74)(H,64,77)(H,66,75)(H,67,73)/t36-,37-,38+,45-,52+,53+,59?/m1/s1	MEKZNRWBMMUXCT-FJHMUCPTSA-N	412175	N-(2-(4-fluoro-3-((S)-2-((S)- 2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindoline-1- carboxamido)benzamido) ethyl)-6-(4-fluorobenzyl)-3- methyl-1-(2-((2R,5R)-5- methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide dihydrochloride::US10398702, Example 14	E3 ubiquitin-protein ligase XIAP [241-356]			 24.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412175&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822166	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C56H68F3N9O7/c1-33-27-66(42(26-61-33)29-65-19-22-75-31-34(65)2)30-48(69)68-32-56(4,44-16-11-37(24-47(44)68)23-36-9-13-40(57)14-10-36)55(73)62-41-15-12-39-28-67(51(43(39)25-41)53(71)64-50-45(58)7-6-8-46(50)59)54(72)49(38-17-20-74-21-18-38)63-52(70)35(3)60-5/h6-16,24-25,33-35,38,42,49,51,60-61H,17-23,26-32H2,1-5H3,(H,62,73)(H,63,70)(H,64,71)/t33-,34-,35+,42-,49+,51+,56-/m1/s1	KKDIBMNGHOWFJB-RABBDSCGSA-N	412176	US10398702, Example 15::tert-Butyl (2R,5S)-4-[2-[(3S)-3-[[(3S)-2-[(2S)-2-[[(2S)-2-[tert-butoxycarbonyl(methyl)amino]propanoyl]amino]-2-tetrahydropyran-4-yl-acetyl]-3-[(2,6-difluorophenyl)carbamoyl]isoindolin-5-yl]carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 9.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412176&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822178	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CCCNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C60H75F3N10O8/c1-36-30-71(45(29-66-36)32-70-22-25-81-34-37(70)2)33-52(75)73-35-60(4,47-18-13-40(27-50(47)73)26-39-11-15-43(61)16-12-39)59(79)65-21-7-10-51(74)67-44-17-14-42-31-72(55(46(42)28-44)57(77)69-54-48(62)8-6-9-49(54)63)58(78)53(41-19-23-80-24-20-41)68-56(76)38(3)64-5/h6,8-9,11-18,27-28,36-38,41,45,53,55,64,66H,7,10,19-26,29-35H2,1-5H3,(H,65,79)(H,67,74)(H,68,76)(H,69,77)/t36-,37-,38+,45-,53+,55+,60-/m1/s1	YAEAYORFJSUSDR-FNAFXGOBSA-N	412179	US10398702, Example 18::tert-Butyl (2R,5S)-4-[2-[(3S)-3-[(4-benzyloxy-4-oxo-butyl)carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 11.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412179&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822182	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2cc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C58H71F3N10O8/c1-34-28-69(43(26-63-34)30-68-19-22-79-32-35(68)2)31-50(73)71-33-58(4,45-16-11-38(24-48(45)71)23-37-9-12-41(59)13-10-37)57(77)64-27-49(72)65-42-14-15-44-40(25-42)29-70(53(44)55(75)67-52-46(60)7-6-8-47(52)61)56(76)51(39-17-20-78-21-18-39)66-54(74)36(3)62-5/h6-16,24-25,34-36,39,43,51,53,62-63H,17-23,26-33H2,1-5H3,(H,64,77)(H,65,72)(H,66,74)(H,67,75)/t34-,35-,36+,43-,51+,53+,58-/m1/s1	GQDXYVZPONPAQI-JHJKZRHASA-N	412180	US10398702, Example 19::tert-Butyl (2R,5S)-4-[2-[(3S)-3-[[2-[[(1S)-2-[(2S)-2-[[(2S)-2-[tert-butoxycarbonyl(methyl)amino]propanoyl]amino]-2-tetrahydropyran-4-yl-acetyl]-1-[(2,6-difluorophenyl)carbamoyl]isoindolin-5-yl]amino]-2-oxo-ethyl]carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 8.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412180&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822190	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1Cc2ccc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C57H71F3N10O7/c1-8-33(2)50(65-53(73)36(5)61-7)55(75)69-28-39-15-18-41(24-43(39)52(69)54(74)66-51-45(59)10-9-11-46(51)60)64-48(71)26-63-56(76)57(6)32-70(47-23-38(14-19-44(47)57)22-37-12-16-40(58)17-13-37)49(72)30-68-27-34(3)62-25-42(68)29-67-20-21-77-31-35(67)4/h9-19,23-24,33-36,42,50,52,61-62H,8,20-22,25-32H2,1-7H3,(H,63,76)(H,64,71)(H,65,73)(H,66,74)/t33-,34+,35+,36-,42+,50-,52-,57+/m0/s1	DWXWQLOMZHEBFQ-GSYKCJHXSA-N	412182	US10398702, Example 21::tert-Butyl (2R,5S)-4-[2-[(3S)-3-[[2-[[(3S)-2-[(2 S,3 S)-2-[[(2S)-2-[tert-butoxycarbonyl(methyl)amino]propanoyl]amino]-3-methyl-pentanoyl]-3-[(2,6-difluorophenyl)carbamoyl]isoindolin-5-yl]amino]-2-oxo-ethyl]carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 6.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412182&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822142	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CNC(=O)[C@@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C58H71F3N10O8/c1-34-28-69(43(26-63-34)30-68-19-22-79-32-35(68)2)31-50(73)71-33-58(4,45-16-11-38(24-48(45)71)23-37-9-13-41(59)14-10-37)57(77)64-27-49(72)65-42-15-12-40-29-70(53(44(40)25-42)55(75)67-52-46(60)7-6-8-47(52)61)56(76)51(39-17-20-78-21-18-39)66-54(74)36(3)62-5/h6-16,24-25,34-36,39,43,51,53,62-63H,17-23,26-33H2,1-5H3,(H,64,77)(H,65,72)(H,66,74)(H,67,75)/t34-,35-,36+,43-,51+,53+,58+/m1/s1	HOKHIOIWTNNVMY-UVOKZHRTSA-N	412170	(3R)-N-[2-[[(3S)-3-[(2,6- difluorophenyl)carbamoyl]- 2-[(2S)-2-[[(2S)-2- (methylamino)propanoyl] amino]-2-(oxan-4-yl)acetyl]- 1,3-dihydroisoindo1-5- yl]amino]-2-oxoethyl]-6-[(4- fluorophenyl)methyl]-3- methyl-1-[2-[(2R,5R)-5- methyl-2-[[(3R)-3- methylmorpholin-4- yl]methyl]piperazin-1- yl]acetyl]-2H-indole-3- carboxamide;trihydrochloride::US10398702, Example 9	E3 ubiquitin-protein ligase XIAP [241-356]			 108							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412170&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822146	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12)C(C)(C)C	InChI=1S/C62H81FN10O7/c1-38-32-71(48(30-65-38)34-70-24-25-80-36-39(70)2)35-55(75)73-37-62(7,50-23-18-42(27-52(50)73)26-41-16-20-46(63)21-17-41)60(79)66-31-54(74)67-47-22-19-44-29-53(58(77)68-51-15-11-13-43-12-9-10-14-49(43)51)72(33-45(44)28-47)59(78)56(61(4,5)6)69-57(76)40(3)64-8/h9-10,12,14,16-23,27-28,38-40,48,51,53,56,64-65H,11,13,15,24-26,29-37H2,1-8H3,(H,66,79)(H,67,74)(H,68,77)(H,69,76)/t38-,39-,40+,48-,51-,53+,56-,62-/m1/s1	BJHUHNWTABFPGG-JBRJAVIZSA-N	412171	(3S)-2-[(2S)-3,3-dimethyl- 2-[[(2S)-2- (methylamino)propanoyl] amino]butanoyl]-7-[[2- [[(3S)-6-[(4- fluorophenyl)methyl]-3- methyl-1-[2-[(2R,5R)-5- methyl-2-[[(3R)-3- methylmorpholin-4- yl]methyl]piperazin-1- yl]acetyl]-2H-indole-3- carbonyl]amino]acetyl] amino]-N-[(1R)-1,2,3,4- tetrahydronaphthalen-1-yl]- 3,4-dihydro-1H- isoquinoline-3- carboxamide;trihydrochloride::US10398702, Example 10	E3 ubiquitin-protein ligase XIAP [241-356]			 2.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412171&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822210	C[C@@H]1CN(CC(=O)N2CC(C)(C(=O)Nc3ccc(cc3)C(O)=O)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C37H44FN5O5/c1-24-19-42(31(18-39-24)20-41-14-15-48-22-25(41)2)21-34(44)43-23-37(3,36(47)40-30-11-7-28(8-12-30)35(45)46)32-13-6-27(17-33(32)43)16-26-4-9-29(38)10-5-26/h4-13,17,24-25,31,39H,14-16,18-23H2,1-3H3,(H,40,47)(H,45,46)/t24-,25-,31-,37?/m1/s1	GQRITZNZNCQQRA-IYLLWGTOSA-N	412187	4-(6-(4-fluorobenzyl)-3- methyl-1-(2-((2R,5R)-5- methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamido)benzoic acid dihydrochloride::US10398702, Example D	E3 ubiquitin-protein ligase XIAP [241-356]			 32.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412187&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822150	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(NC(=O)CNC(=O)[C@@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12)C(C)(C)C	InChI=1S/C62H81FN10O7/c1-38-32-71(48(30-65-38)34-70-24-25-80-36-39(70)2)35-55(75)73-37-62(7,50-23-18-42(27-52(50)73)26-41-16-20-46(63)21-17-41)60(79)66-31-54(74)67-47-22-19-44-29-53(58(77)68-51-15-11-13-43-12-9-10-14-49(43)51)72(33-45(44)28-47)59(78)56(61(4,5)6)69-57(76)40(3)64-8/h9-10,12,14,16-23,27-28,38-40,48,51,53,56,64-65H,11,13,15,24-26,29-37H2,1-8H3,(H,66,79)(H,67,74)(H,68,77)(H,69,76)/t38-,39-,40+,48-,51-,53+,56-,62+/m1/s1	BJHUHNWTABFPGG-CYLUITCRSA-N	412172	(3S)-2-[(2S)-3,3-dimethyl-2- [[(2S)-2- (methylamino)propanoyl] amino]butanoyl]-7-[[2- [[(3R)-6- [(4-fluorophenyl)methyl]-3- methyl-1-[2-[(2R,5R)-5- methyl-2-[[(3R)-3- methylmorpholin-4- yl]methyl]piperazin-1- yl]acetyl]-2H-indole-3- carbonyl]amino]acetyl] amino]-N-[(1R)-1,2,3,4- tetrahydronaphthalen-1-yl]- 3,4-dihydro-1H- isoquinoline-3- carboxamide;trihydrochloride::US10398702, Example 11	E3 ubiquitin-protein ligase XIAP [241-356]			 18.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412172&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822154	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)[C@@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C56H68F3N9O7/c1-33-27-66(42(26-61-33)29-65-19-22-75-31-34(65)2)30-48(69)68-32-56(4,44-16-11-37(24-47(44)68)23-36-9-13-40(57)14-10-36)55(73)62-41-15-12-39-28-67(51(43(39)25-41)53(71)64-50-45(58)7-6-8-46(50)59)54(72)49(38-17-20-74-21-18-38)63-52(70)35(3)60-5/h6-16,24-25,33-35,38,42,49,51,60-61H,17-23,26-32H2,1-5H3,(H,62,73)(H,63,70)(H,64,71)/t33-,34-,35+,42-,49+,51+,56+/m1/s1	KKDIBMNGHOWFJB-QPVRNIJESA-N	412173	(R)-N-((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((S)-2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindolin-5-yl)-6- (4-fluorobenzyl)-3-methyl-1- (2-((2R,5R)-5-methyl-2- (((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 12	E3 ubiquitin-protein ligase XIAP [241-356]			 17.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412173&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822194	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2ccc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F)C(C)(C)C	InChI=1S/C57H71F3N10O7/c1-33-27-68(41(25-62-33)29-67-20-21-77-31-34(67)2)30-48(72)70-32-57(7,43-19-14-37(23-46(43)70)22-36-12-16-39(58)17-13-36)55(76)63-26-47(71)64-40-18-15-38-28-69(54(75)51(56(4,5)6)66-52(73)35(3)61-8)50(42(38)24-40)53(74)65-49-44(59)10-9-11-45(49)60/h9-19,23-24,33-35,41,50-51,61-62H,20-22,25-32H2,1-8H3,(H,63,76)(H,64,71)(H,65,74)(H,66,73)/t33-,34-,35+,41-,50+,51-,57-/m1/s1	IBZIIVISPQLELC-CEHVYTRKSA-N	412183	US10398702, Example 22::tert-Butyl (2R,5S)-4-[2-[(3S)-3-[[2-[[(3S)-2-[(2S)-2-[[(2S)-2-[tert-butoxycarbonyl(methyl)amino]propanoyl]amino]-3,3-dimethyl-butanoyl]-3-[(2,6-difluorophenyl)carbamoyl]isoindolin-5-yl]amino]-2-oxo-ethyl]carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 9.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412183&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822170	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccccc2[C@H]1C(=O)Nc1cc(ccc1F)C(=O)Nc1ccc(NC(=O)C2(C)CN(C(=O)CN3C[C@@H](C)NC[C@@H]3CN3CCOC[C@H]3C)c3cc(Cc4ccc(F)cc4)ccc23)cc1	InChI=1S/C63H74F2N10O8/c1-38-32-73(49(31-67-38)34-72-24-27-83-36-39(72)2)35-55(76)75-37-63(4,51-20-12-42(29-54(51)75)28-41-10-14-46(64)15-11-41)62(81)69-48-18-16-47(17-19-48)68-59(78)44-13-21-52(65)53(30-44)70-60(79)57-50-9-7-6-8-45(50)33-74(57)61(80)56(43-22-25-82-26-23-43)71-58(77)40(3)66-5/h6-21,29-30,38-40,43,49,56-57,66-67H,22-28,31-37H2,1-5H3,(H,68,78)(H,69,81)(H,70,79)(H,71,77)/t38-,39-,40+,49-,56+,57+,63?/m1/s1	CVZJCEWUSZWWLC-IKPIZQADSA-N	412177	N-(4-(4-fluoro-3-((S)-2-((S)- 2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindoline-1- carboxamido)benzamido) phenyl)-6-(4-fluorobenzyl)- 3-methyl-1-(2-((2R,5R)-5- methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 16	E3 ubiquitin-protein ligase XIAP [241-356]			 36.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412177&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822186	CN[C@@H](C)C(=O)N[C@@H]([C@@H](C)OC)C(=O)N1Cc2ccc(NC(=O)CNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C56H69F3N10O8/c1-32-26-67(41(24-61-32)28-66-19-20-77-30-33(66)2)29-48(71)69-31-56(5,43-18-13-37(22-46(43)69)21-36-11-15-39(57)16-12-36)55(75)62-25-47(70)63-40-17-14-38-27-68(54(74)49(35(4)76-7)64-52(72)34(3)60-6)51(42(38)23-40)53(73)65-50-44(58)9-8-10-45(50)59/h8-18,22-23,32-35,41,49,51,60-61H,19-21,24-31H2,1-7H3,(H,62,75)(H,63,70)(H,64,72)(H,65,73)/t32-,33-,34+,35-,41-,49+,51+,56-/m1/s1	GQJBERRGZSKOOZ-ZYKJTKOSSA-N	412181	(S)-N-(2-(((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((2S,3R)-3-methoxy-2- ((S)-2- (methylamino)propanamido) butanoyl)isoindolin-5- yl)amino)-2-oxoethyl)-6-(4- fluorobenzyl)-3-methyl-1-(2- ((2R,5R)-5-methyl-2-(((R)- 3-methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 20	E3 ubiquitin-protein ligase XIAP [241-356]			 5.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412181&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822214	C[C@@H]1CN(CC(=O)N2CC(C)(C(=O)NCC(O)=O)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C32H42FN5O5/c1-21-16-37(26(14-34-21)17-36-10-11-43-19-22(36)2)18-29(39)38-20-32(3,31(42)35-15-30(40)41)27-9-6-24(13-28(27)38)12-23-4-7-25(33)8-5-23/h4-9,13,21-22,26,34H,10-12,14-20H2,1-3H3,(H,35,42)(H,40,41)/t21-,22-,26-,32?/m1/s1	WQMGHGPQSDYHHQ-FIMFUJOFSA-N	412188	2-(6-(4-fluorobenzyl)-3- methyl-1-(2-((2R,5R)-5- methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamido)acetic acid dihydrochloride::US10398702, Example E	E3 ubiquitin-protein ligase XIAP [241-356]			 56.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412188&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822198	C[C@@H]1CN(CC(=O)N2CC(C)(C(=O)NCCN)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C32H45FN6O3/c1-22-17-38(27(16-36-22)18-37-12-13-42-20-23(37)2)19-30(40)39-21-32(3,31(41)35-11-10-34)28-9-6-25(15-29(28)39)14-24-4-7-26(33)8-5-24/h4-9,15,22-23,27,36H,10-14,16-21,34H2,1-3H3,(H,35,41)/t22-,23-,27-,32?/m1/s1	LQOKEIHVFLUEOJ-HBIGZJEKSA-N	412184	N-(2-aminoethyl)-6-(4- fluorobenzyl)-3-methyl-1- (2-((2R,5R)-5-methyl-2- (((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide dihydrochloride::US10398702, Example A	E3 ubiquitin-protein ligase XIAP [241-356]			 41.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412184&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822202	C[C@@H]1CN(CC(=O)N2C[C@@](C)(C(O)=O)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C30H39FN4O4/c1-20-15-34(25(14-32-20)16-33-10-11-39-18-21(33)2)17-28(36)35-19-30(3,29(37)38)26-9-6-23(13-27(26)35)12-22-4-7-24(31)8-5-22/h4-9,13,20-21,25,32H,10-12,14-19H2,1-3H3,(H,37,38)/t20-,21-,25-,30-/m1/s1	AEKQSNLWAKMPDL-NITIVINISA-N	412185	(S)-6-(4-fluorobenzyl)-3- methyl-1-(2-((2R,5R)-5- methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxylic acid dihydrochloride::US10398702, Example B	E3 ubiquitin-protein ligase XIAP [241-356]			 68.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412185&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822206	C[C@@H]1CN(CC(=O)N2CC(C)(CO)c3ccc(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1	InChI=1S/C30H41FN4O3/c1-21-15-34(26(14-32-21)16-33-10-11-38-18-22(33)2)17-29(37)35-19-30(3,20-36)27-9-6-24(13-28(27)35)12-23-4-7-25(31)8-5-23/h4-9,13,21-22,26,32,36H,10-12,14-20H2,1-3H3/t21-,22-,26-,30?/m1/s1	VHDDFOLGLBDAEY-FRJRRQFFSA-N	412186	1-(6-(4-fluorobenzyl)-3- (hydroxymethyl)-3- methylindolin-1-yl)-2- ((2R,5R)-5-methyl-2-(((R)- 3-methylmorpholino)methyl) piperazin-1-yl)ethanone dihydrochloride::US10398702, Example C	E3 ubiquitin-protein ligase XIAP [241-356]			 38.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412186&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822110	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C56H68F3N9O7/c1-33-27-66(42(26-61-33)29-65-19-22-75-31-34(65)2)30-48(69)68-32-56(4,44-16-11-37(24-47(44)68)23-36-9-13-40(57)14-10-36)55(73)62-41-15-12-39-28-67(51(43(39)25-41)53(71)64-50-45(58)7-6-8-46(50)59)54(72)49(38-17-20-74-21-18-38)63-52(70)35(3)60-5/h6-16,24-25,33-35,38,42,49,51,60-61H,17-23,26-32H2,1-5H3,(H,62,73)(H,63,70)(H,64,71)/t33-,34-,35+,42-,49+,51+,56?/m1/s1	KKDIBMNGHOWFJB-TZDRKILZSA-N	412162	N-((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((S)-2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindolin-5-yl)-6- (4-fluorobenzyl)-3-methyl-1- (2-((2R,5R)-5-methyl-2- (((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 1	E3 ubiquitin-protein ligase XIAP [241-356]			 11.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412162&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822114	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CNC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C58H71F3N10O8/c1-34-28-69(43(26-63-34)30-68-19-22-79-32-35(68)2)31-50(73)71-33-58(4,45-16-11-38(24-48(45)71)23-37-9-13-41(59)14-10-37)57(77)64-27-49(72)65-42-15-12-40-29-70(53(44(40)25-42)55(75)67-52-46(60)7-6-8-47(52)61)56(76)51(39-17-20-78-21-18-39)66-54(74)36(3)62-5/h6-16,24-25,34-36,39,43,51,53,62-63H,17-23,26-33H2,1-5H3,(H,64,77)(H,65,72)(H,66,74)(H,67,75)/t34-,35-,36+,43-,51+,53+,58?/m1/s1	HOKHIOIWTNNVMY-SJHREDNESA-N	412163	N-(2-(((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((S)-2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindolin-5- yl)amino)-2-oxoethyl)-6-(4- fluorobenzyl)-3-methyl-1-(2- ((2R,5R)-5-methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 2	E3 ubiquitin-protein ligase XIAP [241-356]			 13.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412163&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822122	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)c3ccc(NC(=O)C4(C)CN(C(=O)CN5C[C@@H](C)NC[C@@H]5CN5CCOC[C@H]5C)c5cc(Cc6ccc(F)cc6)ccc45)cc3)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C63H73F3N10O8/c1-37-31-74(48(30-68-37)33-73-23-26-84-35-38(73)2)34-54(77)76-36-63(4,50-20-11-41(28-53(50)76)27-40-9-15-45(64)16-10-40)62(82)70-46-17-12-43(13-18-46)59(79)69-47-19-14-44-32-75(57(49(44)29-47)60(80)72-56-51(65)7-6-8-52(56)66)61(81)55(42-21-24-83-25-22-42)71-58(78)39(3)67-5/h6-20,28-29,37-39,42,48,55,57,67-68H,21-27,30-36H2,1-5H3,(H,69,79)(H,70,82)(H,71,78)(H,72,80)/t37-,38-,39+,48-,55+,57+,63?/m1/s1	YAZQOISVPGFMGA-JCSBTUTESA-N	412165	N-(4-(((S)-3-((2,6- difluorophenyl)carbamoyl)- 2-((S)-2-((S)-2- (methylamino)propanamido)- 2-(tetrahydro-2H-pyran-4- yl)acetyl)isoindolin-5- yl)carbamoyl)phenyl)-6-(4- fluorobenzyl)-3-methyl-1-(2- ((2R,5R)-5-methyl-2-(((R)-3- methylmorpholino)methyl) piperazin-1- yl)acetyl)indoline-3- carboxamide trihydrochloride::US10398702, Example 4	E3 ubiquitin-protein ligase XIAP [241-356]			 13.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412165&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822126	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(NC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2CC1C(=O)N[C@@H]1CCCc2ccccc12)C(C)(C)C	InChI=1S/C60H78FN9O6/c1-37-31-68(47(30-63-37)33-67-24-25-76-35-38(67)2)34-53(71)70-36-60(7,49-23-18-41(27-51(49)70)26-40-16-20-45(61)21-17-40)58(75)64-46-22-19-43-29-52(56(73)65-50-15-11-13-42-12-9-10-14-48(42)50)69(32-44(43)28-46)57(74)54(59(4,5)6)66-55(72)39(3)62-8/h9-10,12,14,16-23,27-28,37-39,47,50,52,54,62-63H,11,13,15,24-26,29-36H2,1-8H3,(H,64,75)(H,65,73)(H,66,72)/t37-,38-,39+,47-,50-,52?,54-,60?/m1/s1	QICFHBQZRMLUEQ-OAYQEPMQSA-N	412166	(3S)-2-((S)-3,3-dimethyl-2- ((S)-2- (methylamino)propanamido) butanoyl)-7-(6-(4- fluorobenzyl)-3-methyl-1-(2- ((2R,5R)-5-methyl-2-(((R)- 3-methylmorpholino)methyl) piperazin-1- yl)acetypindoline-3- carboxamido)-N-((R)- 1,2,3,4-tetrahydronaphthalen- 1-yl)-1,2,3,4- tetrahydroisoquinoline-3- carboxamide trihydrochloride::US10398702, Example 5	E3 ubiquitin-protein ligase XIAP [241-356]			 3.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412166&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822158	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2cc(NC(=O)CNC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2C[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C59H73F3N10O8/c1-35-29-70(45(27-64-35)31-69-19-22-80-33-36(69)2)32-52(74)72-34-59(4,46-16-11-39(24-49(46)72)23-38-9-13-43(60)14-10-38)58(78)65-28-51(73)66-44-15-12-41-26-50(56(76)68-54-47(61)7-6-8-48(54)62)71(30-42(41)25-44)57(77)53(40-17-20-79-21-18-40)67-55(75)37(3)63-5/h6-16,24-25,35-37,40,45,50,53,63-64H,17-23,26-34H2,1-5H3,(H,65,78)(H,66,73)(H,67,75)(H,68,76)/t35-,36-,37+,45-,50+,53+,59?/m1/s1	NWNOURIQTQGEHG-SHVDBAOHSA-N	412174	US10398702, Example 13::tert-Butyl (2R,5S)-4-[2-[3-[[2-[[(3S)-2-[(2S)-2-[[(2S)-2-[tert-butoxycarbonyl(methyl)amino]propanoyl]amino]-2-tetrahydropyran-4-yl-acetyl]-3-[(2,6-difluorophenyl)carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]amino]-2-oxo-ethyl]carbamoyl]-6-[(4-fluorophenyl)methyl]-3-methyl-indolin-1-yl]-2-oxo-ethyl]-2-methyl-5-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazine-1-carboxylate	E3 ubiquitin-protein ligase XIAP [241-356]			 29.0							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412174&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822130	CN[C@@H](C)C(=O)N[C@H](C(=O)N1Cc2cc(NC(=O)CNC(=O)C3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12)C(C)(C)C	InChI=1S/C62H81FN10O7/c1-38-32-71(48(30-65-38)34-70-24-25-80-36-39(70)2)35-55(75)73-37-62(7,50-23-18-42(27-52(50)73)26-41-16-20-46(63)21-17-41)60(79)66-31-54(74)67-47-22-19-44-29-53(58(77)68-51-15-11-13-43-12-9-10-14-49(43)51)72(33-45(44)28-47)59(78)56(61(4,5)6)69-57(76)40(3)64-8/h9-10,12,14,16-23,27-28,38-40,48,51,53,56,64-65H,11,13,15,24-26,29-37H2,1-8H3,(H,66,79)(H,67,74)(H,68,77)(H,69,76)/t38-,39-,40+,48-,51-,53+,56-,62?/m1/s1	BJHUHNWTABFPGG-LNFVYUFUSA-N	412167	(3S)-2-((S)-3,3-dimethyl- 2-((S)-2- (methylamino)propanamido) butanoyl)-7-(2-(6-(4- fluorobenzyl)-3-methyl-1- (2-((2R,5R)-5-methyl-2- (((R)-3 methylmorpholino)methyl) piperazin-1-yl)acetyl)indoline- 3-carboxamido)acetamido)- N-((R)-1,2,3,4- tetrahydronaphthalen-1- yl)-1,2,3,4- tetrahydroisoquinoline-3- carboxamide trihydrochloride::US10398702, Example 6	E3 ubiquitin-protein ligase XIAP [241-356]			 8.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412167&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14						
822174	CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1Cc2ccc(NC(=O)CCNC(=O)[C@]3(C)CN(C(=O)CN4C[C@@H](C)NC[C@@H]4CN4CCOC[C@H]4C)c4cc(Cc5ccc(F)cc5)ccc34)cc2[C@H]1C(=O)Nc1c(F)cccc1F	InChI=1S/C59H73F3N10O8/c1-35-29-70(44(28-65-35)31-69-21-24-80-33-36(69)2)32-51(74)72-34-59(4,46-16-11-39(26-49(46)72)25-38-9-13-42(60)14-10-38)58(78)64-20-17-50(73)66-43-15-12-41-30-71(54(45(41)27-43)56(76)68-53-47(61)7-6-8-48(53)62)57(77)52(40-18-22-79-23-19-40)67-55(75)37(3)63-5/h6-16,26-27,35-37,40,44,52,54,63,65H,17-25,28-34H2,1-5H3,(H,64,78)(H,66,73)(H,67,75)(H,68,76)/t35-,36-,37+,44-,52+,54+,59-/m1/s1	MPHZACABYPVWIA-VGWQXMOOSA-N	412178	US10398702, Example 17::tert-Butyl N-[(1 S)-2-[[(1 S)-2-[(1 S)-5-[3-(benzylamino)propanoylamino]-1-[(2,6-difluorophenyl)carbamoyl]isoindolin-2-yl]-2-oxo-1-tetrahydropyran-4-yl-ethyl]amino]-1-methyl-2-oxo-ethyl]-N-methyl-carbamate	E3 ubiquitin-protein ligase XIAP [241-356]			 7.00							US Patent		10.7270/Q2VH5R67		aid1803785	US10398702	Flohr, A; Galley, G; Norcross, R; Zorn, N	Hoffmann-La Roche Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=412178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=404&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=412178&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search											1	MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT	1G3F,1G73,1NW9,1TFQ,1TFT,2JK7,2OPY,2OPZ,2VSL,3CLX,3CM2,3CM7,3EYL,3G76,3HL5,4EC4,4HY0,6EY2,8GH7	E3 ubiquitin-protein ligase XIAP	XIAP_HUMAN	P98170	D3DTF2 Q9NQ14