BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 198871 Oc1ccc(cc1)C1NN=C(S1)c1ccccc1 InChI=1S/C14H12N2OS/c17-12-8-6-11(7-9-12)14-16-15-13(18-14)10-4-2-1-3-5-10/h1-9,14,16-17H UAYJSAALHQXXRV-UHFFFAOYSA-N 158508 US9034574, XVII Methyl-CpG-binding protein 2 16900 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158508&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 577855 277284616 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198872 Clc1ccc(cc1)C1NN=C(S1)c1ccccc1 InChI=1S/C14H11ClN2S/c15-12-8-6-11(7-9-12)14-17-16-13(18-14)10-4-2-1-3-5-10/h1-9,14,17H FJPCKWLGUUDTOP-UHFFFAOYSA-N 158511 US9034574, XXI Methyl-CpG-binding protein 2 33900 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158511&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 2861132 277284619 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198873 OC1(CC(=NN1C(=S)c1ccccc1)c1ccccc1)C(F)(F)F InChI=1S/C17H13F3N2OS/c18-17(19,20)16(23)11-14(12-7-3-1-4-8-12)21-22(16)15(24)13-9-5-2-6-10-13/h1-10,23H,11H2 RIANETHNVIQQBE-UHFFFAOYSA-N 158510 US9034574, XX Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158510&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 3693663 277284618 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198874 Oc1ccc2ccccc2c1C1NN=C(S1)c1ccccc1 InChI=1S/C18H14N2OS/c21-15-11-10-12-6-4-5-9-14(12)16(15)18-20-19-17(22-18)13-7-2-1-3-8-13/h1-11,18,20-21H QIHMPEZAXBQNBF-UHFFFAOYSA-N 158512 US9034574, XXII Methyl-CpG-binding protein 2 610 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158512&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 3136570 277284620 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198875 Oc1cccc(Nc2nc(cs2)-c2ccccn2)c1 InChI=1S/C14H11N3OS/c18-11-5-3-4-10(8-11)16-14-17-13(9-19-14)12-6-1-2-7-15-12/h1-9,18H,(H,16,17) GIGNWEDIMLUWCT-UHFFFAOYSA-N 158506 US9034574, II Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158506&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 704347 277284614 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198876 N(c1nc(cs1)-c1ccccn1)c1ccccn1 InChI=1S/C13H10N4S/c1-3-7-14-10(5-1)11-9-18-13(16-11)17-12-6-2-4-8-15-12/h1-9H,(H,15,16,17) RYCUBTFYRLAMFA-UHFFFAOYSA-N 50264020 CHEMBL489770::GNF-PF-4773::N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-amine::TCMDC-124275::US9034574, I Methyl-CpG-binding protein 2 10460 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264020&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 772885 104112154 CHEMBL489770 ZINC00257247 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198877 Cn1c2ccccc2n2cc(nc12)-c1ccc(cc1)[N+]([O-])=O InChI=1S/C16H12N4O2/c1-18-14-4-2-3-5-15(14)19-10-13(17-16(18)19)11-6-8-12(9-7-11)20(21)22/h2-10H,1H3 IBVRCTVMEOHDDP-UHFFFAOYSA-N 158507 US9034574, Add::US9034574, III Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158507&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 781030 277284615 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198878 COc1cc(O)cc(Br)c1\C=N\Nc1nc2ccccc2s1 InChI=1S/C15H12BrN3O2S/c1-21-13-7-9(20)6-11(16)10(13)8-17-19-15-18-12-4-2-3-5-14(12)22-15/h2-8,20H,1H3,(H,18,19)/b17-8+ CAYPYIUGJJUJJP-CAOOACKPSA-N 158509 US9034574, XVIII Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158509&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 5341491 277284617 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198879 COc1ccccc1-c1nc(no1)-c1cccc(c1)[N+]([O-])=O InChI=1S/C15H11N3O4/c1-21-13-8-3-2-7-12(13)15-16-14(17-22-15)10-5-4-6-11(9-10)18(19)20/h2-9H,1H3 RVXOFACJJMKRHR-UHFFFAOYSA-N 47365 US9034574, X Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47365&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 2063595 24829766 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198880 Nc1cccc(c1)-c1nnc(o1)-c1ccccc1 InChI=1S/C14H11N3O/c15-12-8-4-7-11(9-12)14-17-16-13(18-14)10-5-2-1-3-6-10/h1-9H,15H2 DOYLAQBXDHFRFB-UHFFFAOYSA-N 47366 US9034574, XXIII Methyl-CpG-binding protein 2 8590 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47366&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 1251301 24832083 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198881 COc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 InChI=1S/C17H15N3O2/c1-22-14-9-7-13(8-10-14)19-17(21)20-15-6-2-4-12-5-3-11-18-16(12)15/h2-11H,1H3,(H2,19,20,21) FGIJPZDUXLSZJI-UHFFFAOYSA-N 47368 BDBM77674::US9034574, XXIV Methyl-CpG-binding protein 2 2810 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47368&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 2172366 24834972 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384 198882 CCOc1ccc(Nc2nc(cs2)-c2ccccn2)cc1 InChI=1S/C16H15N3OS/c1-2-20-13-8-6-12(7-9-13)18-16-19-15(11-21-16)14-5-3-4-10-17-14/h3-11H,2H2,1H3,(H,18,19) GPCRTKWGISPUOU-UHFFFAOYSA-N 47369 US9034574, XXV Methyl-CpG-binding protein 2 >200000 US Patent 10.7270/Q2RF5SSN aid1801234 US9034574 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z The Johns Hopkins University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=34&target=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47369&enzyme=Methyl-CpG-binding+protein+2&column=ki&startPg=0&Increment=50&submit=Search 723168 24836763 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 1QK9,1UB1,6OGJ,6OGK,6YWW,8AJR,8ALQ Methyl-CpG-binding protein 2 MECP2_HUMAN P51608 O15233 Q6QHH9 Q7Z384