BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 42545 COC(=O)[C@]1(C[C@@H]1C(=O)NO)c1cccc(OCc2ccccc2)c1 InChI=1S/C19H19NO5/c1-24-18(22)19(11-16(19)17(21)20-23)14-8-5-9-15(10-14)25-12-13-6-3-2-4-7-13/h2-10,16,23H,11-12H2,1H3,(H,20,21)/t16-,19-/m1/s1 GVBYOUWYVHIZCE-VQIMIIECSA-N 23452 hydroxamate deriv., 4::methyl (1S,2S)-1-[3-(benzyloxy)phenyl]-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 190 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23452&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 9862812 50091715 ZINC29134806 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42546 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C23H22N2O5/c1-14-10-15(18-8-3-4-9-20(18)24-14)13-30-17-7-5-6-16(11-17)23(22(27)29-2)12-19(23)21(26)25-28/h3-11,19,28H,12-13H2,1-2H3,(H,25,26)/t19-,23-/m0/s1 VQLUSPJMTIROIO-CVDCTZTESA-N 23454 CHEMBL270558::hydroxamate deriv., 26::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 12 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23454&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24800654 50091716 CHEMBL270558 ZINC29134794 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42547 Cc1cc(COc2cccc(c2)[C@]2(C[C@H]2C(=O)NO)C(N)=O)c2ccccc2n1 InChI=1S/C22H21N3O4/c1-13-9-14(17-7-2-3-8-19(17)24-13)12-29-16-6-4-5-15(10-16)22(21(23)27)11-18(22)20(26)25-28/h2-10,18,28H,11-12H2,1H3,(H2,23,27)(H,25,26)/t18-,22-/m0/s1 LOEOATDRPRNXBR-AVRDEDQJSA-N 23455 (1R,2R)-1-N-hydroxy-2-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 29 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 700 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23455&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24800829 50091717 ZINC29134751 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42548 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccc(Cl)c(Cl)c2)c1 InChI=1S/C19H17Cl2NO5/c1-26-18(24)19(9-14(19)17(23)22-25)12-3-2-4-13(8-12)27-10-11-5-6-15(20)16(21)7-11/h2-8,14,25H,9-10H2,1H3,(H,22,23)/t14-,19-/m0/s1 DURBSUHKVDBUEW-LIRRHRJNSA-N 23456 hydroxamate deriv., 44::methyl (1R,2R)-1-{3-[(3,4-dichlorophenyl)methoxy]phenyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 11 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23456&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801010 50091718 ZINC29134745 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42549 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(Oc2ccccc2)c1 InChI=1S/C18H17NO5/c1-23-17(21)18(11-15(18)16(20)19-22)12-6-5-9-14(10-12)24-13-7-3-2-4-8-13/h2-10,15,22H,11H2,1H3,(H,19,20)/t15-,18-/m0/s1 CPYMYVGMNPHMIG-YJBOKZPZSA-N 23457 hydroxamate deriv., 45::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-phenoxyphenyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 1100 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23457&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799267 50091719 ZINC29134747 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42550 CC(C)OC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C25H26N2O5/c1-15(2)32-24(29)25(13-21(25)23(28)27-30)18-7-6-8-19(12-18)31-14-17-11-16(3)26-22-10-5-4-9-20(17)22/h4-12,15,21,30H,13-14H2,1-3H3,(H,27,28)/t21-,25-/m0/s1 VSJXDGBUEWZGHU-OFVILXPXSA-N 23458 hydroxamate deriv., 48::propan-2-yl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 8 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23458&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801011 50091720 ZINC29135541 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42551 Cc1cc(COc2cccc(c2)[C@]2(C[C@H]2C(=O)NO)C(=O)NCc2ccccc2)c2ccccc2n1 InChI=1S/C29H27N3O4/c1-19-14-21(24-12-5-6-13-26(24)31-19)18-36-23-11-7-10-22(15-23)29(16-25(29)27(33)32-35)28(34)30-17-20-8-3-2-4-9-20/h2-15,25,35H,16-18H2,1H3,(H,30,34)(H,32,33)/t25-,29-/m0/s1 MNWRESBWEYCTLP-SVEHJYQDSA-N 23459 (1R,2R)-1-N-benzyl-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 49 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 140 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23459&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801012 50091721 ZINC29135539 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42552 NC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccccc2)c1 InChI=1S/C18H18N2O4/c19-17(22)18(10-15(18)16(21)20-23)13-7-4-8-14(9-13)24-11-12-5-2-1-3-6-12/h1-9,15,23H,10-11H2,(H2,19,22)(H,20,21)/t15-,18-/m0/s1 NIKMJLUIYYZWFB-YJBOKZPZSA-N 23460 (1R,2R)-1-[3-(benzyloxy)phenyl]-2-N-hydroxycyclopropane-1,2-dicarboxamide::Racemate::hydroxamate deriv., 52 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 1200 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23460&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10172010 50091722 ZINC29135468 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42553 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OC)c1 InChI=1S/C13H15NO5/c1-18-9-5-3-4-8(6-9)13(12(16)19-2)7-10(13)11(15)14-17/h3-6,10,17H,7H2,1-2H3,(H,14,15)/t10-,13-/m0/s1 LVHUOQQHFDHTIE-GWCFXTLKSA-N 23461 hydroxamate deriv., 53::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-methoxyphenyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3000 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23461&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801013 50091723 ZINC29135458 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42554 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cccc(OC)c2)c1 InChI=1S/C20H21NO6/c1-25-15-7-3-5-13(9-15)12-27-16-8-4-6-14(10-16)20(19(23)26-2)11-17(20)18(22)21-24/h3-10,17,24H,11-12H2,1-2H3,(H,21,22)/t17-,20-/m0/s1 MYZBBCQWECBDNK-PXNSSMCTSA-N 23462 hydroxamate deriv., 54::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(3-methoxyphenyl)methoxy]phenyl}cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 110 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23462&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801014 50091724 ZINC29135382 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42555 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cccc(c2)C(F)(F)F)c1 InChI=1S/C20H18F3NO5/c1-28-18(26)19(10-16(19)17(25)24-27)13-5-3-7-15(9-13)29-11-12-4-2-6-14(8-12)20(21,22)23/h2-9,16,27H,10-11H2,1H3,(H,24,25)/t16-,19-/m0/s1 HFBCDWUJKHOSLS-LPHOPBHVSA-N 23463 hydroxamate deriv., 55::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-{[3-(trifluoromethyl)phenyl]methoxy}phenyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 70 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23463&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799268 50091725 ZINC29135384 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42556 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccc(cc2)C(F)(F)F)c1 InChI=1S/C20H18F3NO5/c1-28-18(26)19(10-16(19)17(25)24-27)14-3-2-4-15(9-14)29-11-12-5-7-13(8-6-12)20(21,22)23/h2-9,16,27H,10-11H2,1H3,(H,24,25)/t16-,19-/m0/s1 HQSYCSALPNGTSD-LPHOPBHVSA-N 23464 hydroxamate deriv., 56::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 18 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23464&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24801015 50091726 ZINC29135381 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42557 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccc(Cl)cc2)c1 InChI=1S/C19H18ClNO5/c1-25-18(23)19(10-16(19)17(22)21-24)13-3-2-4-15(9-13)26-11-12-5-7-14(20)8-6-12/h2-9,16,24H,10-11H2,1H3,(H,21,22)/t16-,19-/m0/s1 ITHBVBYDVWARMD-LPHOPBHVSA-N 23465 hydroxamate deriv., 57::methyl (1R,2R)-1-{3-[(4-chlorophenyl)methoxy]phenyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 50 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10237300 50091727 ZINC29135312 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42558 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cccc(F)c2)c1 InChI=1S/C19H18FNO5/c1-25-18(23)19(10-16(19)17(22)21-24)13-5-3-7-15(9-13)26-11-12-4-2-6-14(20)8-12/h2-9,16,24H,10-11H2,1H3,(H,21,22)/t16-,19-/m0/s1 IORRFRJDHULMSQ-LPHOPBHVSA-N 23466 hydroxamate deriv., 58::methyl (1R,2R)-1-{3-[(3-fluorophenyl)methoxy]phenyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 80 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23466&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799438 50091728 ZINC29135314 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42559 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccc3ccccc3c2)c1 InChI=1S/C23H21NO5/c1-28-22(26)23(13-20(23)21(25)24-27)18-7-4-8-19(12-18)29-14-15-9-10-16-5-2-3-6-17(16)11-15/h2-12,20,27H,13-14H2,1H3,(H,24,25)/t20-,23-/m0/s1 RBSUCNUKTNDLBX-REWPJTCUSA-N 23467 hydroxamate deriv., 59::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(naphthalen-2-ylmethoxy)phenyl]cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3000 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23467&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799439 50091729 ZINC29135310 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42560 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCCc2ccccc2)c1 InChI=1S/C20H21NO5/c1-25-19(23)20(13-17(20)18(22)21-24)15-8-5-9-16(12-15)26-11-10-14-6-3-2-4-7-14/h2-9,12,17,24H,10-11,13H2,1H3,(H,21,22)/t17-,20-/m0/s1 VZOJUACXRRBOTB-PXNSSMCTSA-N 23468 hydroxamate deriv., 60::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(2-phenylethoxy)phenyl]cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 290 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23468&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10215513 50091730 ZINC29135308 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42561 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCCc2ccc3ccccc3c2)c1 InChI=1S/C24H23NO5/c1-29-23(27)24(15-21(24)22(26)25-28)19-7-4-8-20(14-19)30-12-11-16-9-10-17-5-2-3-6-18(17)13-16/h2-10,13-14,21,28H,11-12,15H2,1H3,(H,25,26)/t21-,24-/m0/s1 WIUQVVMGJZANSX-URXFXBBRSA-N 23469 hydroxamate deriv., 61::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[2-(naphthalen-2-yl)ethoxy]phenyl}cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 60 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23469&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10126803 50091731 ZINC29135240 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42562 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCCc2cccc(\C=C/C=C)c2)c1 InChI=1S/C24H25NO5/c1-3-4-7-17-8-5-9-18(14-17)12-13-30-20-11-6-10-19(15-20)24(23(27)29-2)16-21(24)22(26)25-28/h3-11,14-15,21,28H,1,12-13,16H2,2H3,(H,25,26)/b7-4-/t21-,24-/m0/s1 YDDKZUMXWMGFOP-FSCAMMEHSA-N 23470 hydroxamate deriv., 62::methyl (1R,2R)-1-[3-(2-{3-[(1Z)-buta-1,3-dien-1-yl]phenyl}ethoxy)phenyl]-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 50 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24860418 50091732 ZINC62153995 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42563 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(Oc2ccc3ccccc3c2)c1 InChI=1S/C22H19NO5/c1-27-21(25)22(13-19(22)20(24)23-26)16-7-4-8-17(12-16)28-18-10-9-14-5-2-3-6-15(14)11-18/h2-12,19,26H,13H2,1H3,(H,23,24)/t19-,22-/m0/s1 SAGRPSRSCCTABN-UGKGYDQZSA-N 23471 hydroxamate deriv., 63::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(naphthalen-2-yloxy)phenyl]cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 70 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799440 50091733 ZINC29135238 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42564 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(Oc2ccccc2C)c1 InChI=1S/C19H19NO5/c1-12-6-3-4-9-16(12)25-14-8-5-7-13(10-14)19(18(22)24-2)11-15(19)17(21)20-23/h3-10,15,23H,11H2,1-2H3,(H,20,21)/t15-,19-/m0/s1 DLYWRRJQIAZFLM-KXBFYZLASA-N 23472 hydroxamate deriv., 64::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(2-methylphenoxy)phenyl]cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 240 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799441 50091734 ZINC29135184 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42565 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(Oc2ccc(C)cc2)c1 InChI=1S/C19H19NO5/c1-12-6-8-14(9-7-12)25-15-5-3-4-13(10-15)19(18(22)24-2)11-16(19)17(21)20-23/h3-10,16,23H,11H2,1-2H3,(H,20,21)/t16-,19-/m0/s1 PDLMEJFFFHKMNV-LPHOPBHVSA-N 23473 hydroxamate deriv., 65::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-[3-(4-methylphenoxy)phenyl]cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 140 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799442 50091735 ZINC29135185 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42566 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCC#CC)c1 InChI=1S/C16H17NO5/c1-3-4-8-22-12-7-5-6-11(9-12)16(15(19)21-2)10-13(16)14(18)17-20/h5-7,9,13,20H,8,10H2,1-2H3,(H,17,18)/t13-,16-/m0/s1 YSRBIYDEEXPRDU-BBRMVZONSA-N 23474 hydroxamate deriv., 66::methyl (1R,2R)-1-[3-(but-2-yn-1-yloxy)phenyl]-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 1600 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23474&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10236529 50091736 ZINC29135187 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42567 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCC2CCCCC2)c1 InChI=1S/C19H25NO5/c1-24-18(22)19(11-16(19)17(21)20-23)14-8-5-9-15(10-14)25-12-13-6-3-2-4-7-13/h5,8-10,13,16,23H,2-4,6-7,11-12H2,1H3,(H,20,21)/t16-,19-/m0/s1 GZQFXDXWCHYZMR-LPHOPBHVSA-N 23475 hydroxamate deriv., 67::methyl (1R,2R)-1-[3-(cyclohexylmethoxy)phenyl]-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 900 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23475&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 10150046 50091737 ZINC29135130 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42568 CCOC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C24H24N2O5/c1-3-30-23(28)24(13-20(24)22(27)26-29)17-7-6-8-18(12-17)31-14-16-11-15(2)25-21-10-5-4-9-19(16)21/h4-12,20,29H,3,13-14H2,1-2H3,(H,26,27)/t20-,24-/m0/s1 HIDYNFFNKYESOB-RDPSFJRHSA-N 23476 ethyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1-carboxylate::hydroxamate deriv., 68 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 16 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799443 50091738 ZINC29135084 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42569 CC(C)NC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C25H27N3O4/c1-15(2)26-24(30)25(13-21(25)23(29)28-31)18-7-6-8-19(12-18)32-14-17-11-16(3)27-22-10-5-4-9-20(17)22/h4-12,15,21,31H,13-14H2,1-3H3,(H,26,30)(H,28,29)/t21-,25-/m0/s1 CWUUNJTYLPBTOO-OFVILXPXSA-N 23477 (1R,2R)-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}-1-N-(propan-2-yl)cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 69 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 5 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799616 50091739 ZINC29135081 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42570 CNC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C23H23N3O4/c1-14-10-15(18-8-3-4-9-20(18)25-14)13-30-17-7-5-6-16(11-17)23(22(28)24-2)12-19(23)21(27)26-29/h3-11,19,29H,12-13H2,1-2H3,(H,24,28)(H,26,27)/t19-,23-/m0/s1 AHGWEVJBCPZWCU-CVDCTZTESA-N 23478 (1R,2R)-2-N-hydroxy-1-N-methyl-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 70 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 100 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799617 50091740 ZINC29135023 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42571 CN(C)C(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C24H25N3O4/c1-15-11-16(19-9-4-5-10-21(19)25-15)14-31-18-8-6-7-17(12-18)24(23(29)27(2)3)13-20(24)22(28)26-30/h4-12,20,30H,13-14H2,1-3H3,(H,26,28)/t20-,24-/m0/s1 NBJXSJRESIAPEZ-RDPSFJRHSA-N 23479 (1R,2R)-2-N-hydroxy-1-N,1-N-dimethyl-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 71 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 2700 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799618 50091741 ZINC29134965 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42572 Cc1cc(COc2cccc(c2)[C@]2(C[C@H]2C(=O)NO)C(=O)Nc2ccccc2)c2ccccc2n1 InChI=1S/C28H25N3O4/c1-18-14-19(23-12-5-6-13-25(23)29-18)17-35-22-11-7-8-20(15-22)28(16-24(28)26(32)31-34)27(33)30-21-9-3-2-4-10-21/h2-15,24,34H,16-17H2,1H3,(H,30,33)(H,31,32)/t24-,28-/m0/s1 CXYDXYHMTVHGIL-CUBQBAPOSA-N 23480 (1R,2R)-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}-1-N-phenylcyclopropane-1,2-dicarboxamide::hydroxamate deriv., 72 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 11 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23480&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799619 50091742 ZINC29134922 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42573 CN(Cc1ccccc1)C(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C30H29N3O4/c1-20-15-22(25-13-6-7-14-27(25)31-20)19-37-24-12-8-11-23(16-24)30(17-26(30)28(34)32-36)29(35)33(2)18-21-9-4-3-5-10-21/h3-16,26,36H,17-19H2,1-2H3,(H,32,34)/t26-,30-/m0/s1 HHOVOSIJHJQMCK-YZNIXAGQSA-N 23481 (1R,2R)-1-N-benzyl-2-N-hydroxy-1-N-methyl-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 73 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3000 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23481&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799620 50091743 ZINC29134920 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42574 Cc1cc(COc2cccc(c2)[C@]2(C[C@H]2C(=O)NO)C(=O)NC2CCCCC2)c2ccccc2n1 InChI=1S/C28H31N3O4/c1-18-14-19(23-12-5-6-13-25(23)29-18)17-35-22-11-7-8-20(15-22)28(16-24(28)26(32)31-34)27(33)30-21-9-3-2-4-10-21/h5-8,11-15,21,24,34H,2-4,9-10,16-17H2,1H3,(H,30,33)(H,31,32)/t24-,28-/m0/s1 ZXMMRYGLIUZGFD-CUBQBAPOSA-N 23482 (1R,2R)-1-N-cyclohexyl-2-N-hydroxy-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 74 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 9 7.3 22.00 C Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23482&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799621 50091744 ZINC29135455 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42575 CN1CCN(CC1)C(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C27H30N4O4/c1-18-14-19(22-8-3-4-9-24(22)28-18)17-35-21-7-5-6-20(15-21)27(16-23(27)25(32)29-34)26(33)31-12-10-30(2)11-13-31/h3-9,14-15,23,34H,10-13,16-17H2,1-2H3,(H,29,32)/t23-,27-/m0/s1 XACGDVHRXILWLO-HOFKKMOUSA-N 23483 (1R,2R)-N-hydroxy-2-[(4-methylpiperazin-1-yl)carbonyl]-2-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1-carboxamide::hydroxamate deriv., 75 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 5000 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23483&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799777 50091745 ZINC29135379 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42576 COC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C24H24N2O5/c1-15-11-17(19-5-3-4-6-21(19)25-15)14-31-18-9-7-16(8-10-18)12-24(23(28)30-2)13-20(24)22(27)26-29/h3-11,20,29H,12-14H2,1-2H3,(H,26,27)/t20-,24+/m1/s1 HJWMYFBKJRVWJY-YKSBVNFPSA-N 23484 CHEMBL410462::hydroxamate deriv., 34::methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 8 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23484&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 550 3EDZ 24800833 50091746 CHEMBL410462 DB07147 ZINC29135377 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42577 COC(=O)[C@@]1(Cc2ccc(OCc3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C20H21NO5/c1-25-19(23)20(12-17(20)18(22)21-24)11-14-7-9-16(10-8-14)26-13-15-5-3-2-4-6-15/h2-10,17,24H,11-13H2,1H3,(H,21,22)/t17-,20+/m1/s1 ZSKKLMIULIVRSI-XLIONFOSSA-N 23485 Racemate::hydroxamate deriv., 76::methyl (1R,2S)-1-{[4-(benzyloxy)phenyl]methyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 800 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23485&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24860419 50091747 ZINC29134798 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42578 NC(=O)[C@@]1(Cc2ccc(OCc3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C19H20N2O4/c20-18(23)19(11-16(19)17(22)21-24)10-13-6-8-15(9-7-13)25-12-14-4-2-1-3-5-14/h1-9,16,24H,10-12H2,(H2,20,23)(H,21,22)/t16-,19+/m1/s1 KJHGYXBQRZPENB-APWZRJJASA-N 23486 (1R,2S)-1-{[4-(benzyloxy)phenyl]methyl}-2-N-hydroxycyclopropane-1,2-dicarboxamide::hydroxamate deriv., 77 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 360 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23486&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799778 50091748 ZINC29135299 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42579 Cc1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2)c2ccccc2n1 InChI=1S/C23H23N3O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-30-17-8-6-15(7-9-17)11-23(22(24)28)12-19(23)21(27)26-29/h2-10,19,29H,11-13H2,1H3,(H2,24,28)(H,26,27)/t19-,23+/m1/s1 ZWPPXQSIUHCIOD-XXBNENTESA-N 23487 (1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::BMCL1954 Compound 3::hydroxamate deriv., 78 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23487&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799779 50091749 ZINC29135236 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42580 CNC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C24H25N3O4/c1-15-11-17(19-5-3-4-6-21(19)26-15)14-31-18-9-7-16(8-10-18)12-24(23(29)25-2)13-20(24)22(28)27-30/h3-11,20,30H,12-14H2,1-2H3,(H,25,29)(H,27,28)/t20-,24+/m1/s1 DUKCODHLTGRCTA-YKSBVNFPSA-N 23488 (1R,2S)-2-N-hydroxy-1-N-methyl-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 79 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 14 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23488&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799780 50091750 ZINC29135234 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42581 CN(C)C(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C25H27N3O4/c1-16-12-18(20-6-4-5-7-22(20)26-16)15-32-19-10-8-17(9-11-19)13-25(24(30)28(2)3)14-21(25)23(29)27-31/h4-12,21,31H,13-15H2,1-3H3,(H,27,29)/t21-,25+/m1/s1 CCKCYJWNJAYJKS-BWKNWUBXSA-N 23489 (1R,2S)-2-N-hydroxy-1-N,1-N-dimethyl-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::hydroxamate deriv., 80 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 1 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23489&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799781 50091751 ZINC29135182 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42582 COC(=O)[C@@]1(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C[C@@H]1C(=O)NO InChI=1S/C20H19Cl2NO5/c1-27-19(25)20(10-15(20)18(24)23-26)9-12-2-5-14(6-3-12)28-11-13-4-7-16(21)17(22)8-13/h2-8,15,26H,9-11H2,1H3,(H,23,24)/t15-,20+/m1/s1 NUJFJWLOHBNAHZ-QRWLVFNGSA-N 23490 hydroxamate deriv., 81::methyl (1R,2S)-1-({4-[(3,4-dichlorophenyl)methoxy]phenyl}methyl)-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 130 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23490&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799782 50091752 ZINC29135180 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42583 COC(=O)[C@@]1(Cc2ccc(OCc3ccccc3Cl)cc2)C[C@@H]1C(=O)NO InChI=1S/C20H20ClNO5/c1-26-19(24)20(11-16(20)18(23)22-25)10-13-6-8-15(9-7-13)27-12-14-4-2-3-5-17(14)21/h2-9,16,25H,10-12H2,1H3,(H,22,23)/t16-,20+/m1/s1 AFYFMFHIBYHSQH-UZLBHIALSA-N 23491 hydroxamate deriv., 82::methyl (1R,2S)-1-({4-[(2-chlorophenyl)methoxy]phenyl}methyl)-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 260 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23491&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799951 50091753 ZINC29135126 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42584 COC(=O)[C@@]1(Cc2ccc(OCCc3cccc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C25H25NO5/c1-30-24(28)25(16-22(25)23(27)26-29)15-17-9-11-20(12-10-17)31-14-13-19-7-4-6-18-5-2-3-8-21(18)19/h2-12,22,29H,13-16H2,1H3,(H,26,27)/t22-,25+/m1/s1 KVMLUEIAXXNHKM-RDGATRHJSA-N 23492 hydroxamate deriv., 83::methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[2-(naphthalen-1-yl)ethoxy]phenyl}methyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens >100000 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23492&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799952 50091754 ZINC29135128 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42585 COC(=O)[C@@]1(Cc2ccc(OCCc3ccc4ccccc4c3)cc2)C[C@@H]1C(=O)NO InChI=1S/C25H25NO5/c1-30-24(28)25(16-22(25)23(27)26-29)15-18-7-10-21(11-8-18)31-13-12-17-6-9-19-4-2-3-5-20(19)14-17/h2-11,14,22,29H,12-13,15-16H2,1H3,(H,26,27)/t22-,25+/m1/s1 IXTZZWZMRYIHAU-RDGATRHJSA-N 23493 hydroxamate deriv., 84::methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[2-(naphthalen-2-yl)ethoxy]phenyl}methyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens >100000 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23493&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799953 50091755 ZINC29135123 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42586 CCOC(=O)[C@@]1(Cc2ccc(Oc3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C20H21NO5/c1-2-25-19(23)20(13-17(20)18(22)21-24)12-14-8-10-16(11-9-14)26-15-6-4-3-5-7-15/h3-11,17,24H,2,12-13H2,1H3,(H,21,22)/t17-,20+/m1/s1 YGEGTSIAKVGXAQ-XLIONFOSSA-N 23494 ethyl (1R,2S)-2-(hydroxycarbamoyl)-1-[(4-phenoxyphenyl)methyl]cyclopropane-1-carboxylate::hydroxamate deriv., 85 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3100 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23494&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799954 50091756 ZINC29135077 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42587 COC(=O)[C@@]1(Cc2ccc(OCC3CCCCC3)cc2)C[C@@H]1C(=O)NO InChI=1S/C20H27NO5/c1-25-19(23)20(12-17(20)18(22)21-24)11-14-7-9-16(10-8-14)26-13-15-5-3-2-4-6-15/h7-10,15,17,24H,2-6,11-13H2,1H3,(H,21,22)/t17-,20+/m1/s1 RERHTZYXQZCDQP-XLIONFOSSA-N 23495 hydroxamate deriv., 86::methyl (1R,2S)-1-{[4-(cyclohexylmethoxy)phenyl]methyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 26000 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23495&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799955 50091757 ZINC29135073 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42588 COC(=O)[C@@]1(Cc2ccc(OCC#CC)cc2)C[C@@H]1C(=O)NO InChI=1S/C17H19NO5/c1-3-4-9-23-13-7-5-12(6-8-13)10-17(16(20)22-2)11-14(17)15(19)18-21/h5-8,14,21H,9-11H2,1-2H3,(H,18,19)/t14-,17+/m1/s1 MDMNUXMCDVYFIQ-PBHICJAKSA-N 23496 hydroxamate deriv., 87::methyl (1R,2S)-1-{[4-(but-2-yn-1-yloxy)phenyl]methyl}-2-(hydroxycarbamoyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 420 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23496&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799956 50091758 ZINC29135074 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42589 CC#CCOc1ccc(C[C@@]2(C[C@@H]2C(=O)NO)C(N)=O)cc1 InChI=1S/C16H18N2O4/c1-2-3-8-22-12-6-4-11(5-7-12)9-16(15(17)20)10-13(16)14(19)18-21/h4-7,13,21H,8-10H2,1H3,(H2,17,20)(H,18,19)/t13-,16+/m1/s1 XSYMYTAWKURPCI-CJNGLKHVSA-N 23497 (1R,2S)-1-{[4-(but-2-yn-1-yloxy)phenyl]methyl}-2-N-hydroxycyclopropane-1,2-dicarboxamide::hydroxamate deriv., 88 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 80 Curated from the literature by BindingDB 10.1021/jm070376o 10.7270/Q2Q23XKR 18247549 aid1798323 Zhu, Z; Mazzola, R; Sinning, L; McKittrick, B; Niu, X; Lundell, D; Sun, J; Orth, P; Guo, Z; Madison, V; Ingram, R; Beyer, BM Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23497&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799957 50091759 ZINC29135021 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48445 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C28H24FN3O4/c29-22-12-17(14-28(27(30)34)15-21(28)26(33)32-35)10-11-25(22)36-16-19-13-24(18-6-2-1-3-7-18)31-23-9-5-4-8-20(19)23/h1-13,21,35H,14-16H2,(H2,30,34)(H,32,33)/t21-,28+/m1/s1 ZVRPHGZPZLMEPV-PIKZIKFNSA-N 26524 (1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 1 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 0.14 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26524&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138228 56464961 ZINC40862219 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48446 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C28H25N3O4/c29-27(33)28(16-23(28)26(32)31-34)15-18-10-12-21(13-11-18)35-17-20-14-25(19-6-2-1-3-7-19)30-24-9-5-4-8-22(20)24/h1-14,23,34H,15-17H2,(H2,29,33)(H,31,32)/t23-,28+/m1/s1 BKHGWMSYWJIRLD-LXFBAYGMSA-N 26525 (1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 2 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 0.18 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26525&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 615 3E8R 24978491 56464962 ZINC40393256 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48447 Cc1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2)c2ccccc2n1 InChI=1S/C23H23N3O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-30-17-8-6-15(7-9-17)11-23(22(24)28)12-19(23)21(27)26-29/h2-10,19,29H,11-13H2,1H3,(H2,24,28)(H,26,27)/t19-,23+/m1/s1 ZWPPXQSIUHCIOD-XXBNENTESA-N 23487 (1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::BMCL1954 Compound 3::hydroxamate deriv., 78 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23487&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 24799779 50091749 ZINC29135236 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48448 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1 YDMIPBHQKFOFQW-NSYGIPOTSA-N 26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 0.06 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 541 2FV5 6914621 56464963 40083 CHEMBL148169 DB07145 ZINC03820969 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48449 ONC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1 InChI=1S/C29H24FN3O4/c30-22-12-18(25-15-29(28(35)32-25)14-21(29)27(34)33-36)10-11-26(22)37-16-19-13-24(17-6-2-1-3-7-17)31-23-9-5-4-8-20(19)23/h1-13,21,25,36H,14-16H2,(H,32,35)(H,33,34)/t21-,25?,29-/m1/s1 GXZZJHWSDNUEIM-MVUYGMRSSA-N 26527 (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-N-hydroxy-4-oxo-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 12 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 6.7 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138229 56464964 ZINC40863708 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48450 ONC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1 InChI=1S/C29H25N3O4/c33-27(32-35)23-15-29(23)16-26(31-28(29)34)19-10-12-21(13-11-19)36-17-20-14-25(18-6-2-1-3-7-18)30-24-9-5-4-8-22(20)24/h1-14,23,26,35H,15-17H2,(H,31,34)(H,32,33)/t23-,26?,29-/m1/s1 ULZGDYWMSFUARP-WMKGGLNKSA-N 26528 (1S,3R)-N-hydroxy-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 13 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 30 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26528&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138230 56464965 ZINC40860875 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48451 ONC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2cccnc2)cc1 InChI=1S/C28H24N4O4/c33-26(32-35)22-13-28(22)14-25(31-27(28)34)17-7-9-20(10-8-17)36-16-19-12-24(18-4-3-11-29-15-18)30-23-6-2-1-5-21(19)23/h1-12,15,22,25,35H,13-14,16H2,(H,31,34)(H,32,33)/t22-,25?,28-/m1/s1 YJHJPUUREORSTQ-RVFKSZKCSA-N 26529 (1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(pyridin-3-yl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 14 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 32 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26529&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138231 56464966 ZINC40860879 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48452 Cc1cc(COc2ccc(cc2)C2C[C@@]3(C[C@@H]3C(=O)NO)C(=O)N2)c2ccccc2n1 InChI=1S/C24H23N3O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-31-17-8-6-15(7-9-17)21-12-24(23(29)26-21)11-19(24)22(28)27-30/h2-10,19,21,30H,11-13H2,1H3,(H,26,29)(H,27,28)/t19-,21?,24-/m1/s1 CHWRXGNKDPYANF-PBFVZKOQSA-N 26530 (1S,3R)-N-hydroxy-6-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-4-oxo-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 15 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 32 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26530&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138232 56464967 ZINC40395073 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48453 ONC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccncc2)cc1 InChI=1S/C28H24N4O4/c33-26(32-35)22-14-28(22)15-25(31-27(28)34)17-5-7-20(8-6-17)36-16-19-13-24(18-9-11-29-12-10-18)30-23-4-2-1-3-21(19)23/h1-13,22,25,35H,14-16H2,(H,31,34)(H,32,33)/t22-,25?,28-/m1/s1 HGLIGFILENTPME-RVFKSZKCSA-N 26531 (1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(pyridin-4-yl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 16 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 33 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26531&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138233 56464968 ZINC40394838 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48454 ONC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)C(F)(F)F)cc1 InChI=1S/C24H20F3N3O4/c25-24(26,27)20-9-14(16-3-1-2-4-18(16)28-20)12-34-15-7-5-13(6-8-15)19-11-23(22(32)29-19)10-17(23)21(31)30-33/h1-9,17,19,33H,10-12H2,(H,29,32)(H,30,31)/t17-,19?,23-/m1/s1 GYOJLALGSGDHCD-QKLBRSPYSA-N 26532 (1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(trifluoromethyl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 17 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 53 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26532&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138234 56464969 ZINC40394335 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48455 CN1C(C[C@@]2(C[C@@H]2C(=O)NO)C1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1 InChI=1S/C30H26FN3O4/c1-34-26(16-30(29(34)36)15-22(30)28(35)33-37)19-11-12-27(23(31)13-19)38-17-20-14-25(18-7-3-2-4-8-18)32-24-10-6-5-9-21(20)24/h2-14,22,26,37H,15-17H2,1H3,(H,33,35)/t22-,26?,30-/m1/s1 NIMFDLGXDWOYBK-YDSPQXFFSA-N 26533 (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-N-hydroxy-5-methyl-4-oxo-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 18 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 137 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26533&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138235 56464970 ZINC40394200 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48456 OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1 InChI=1S/C29H23FN2O4/c30-22-12-18(25-15-29(28(35)32-25)14-21(29)27(33)34)10-11-26(22)36-16-19-13-24(17-6-2-1-3-7-17)31-23-9-5-4-8-20(19)23/h1-13,21,25H,14-16H2,(H,32,35)(H,33,34)/t21-,25?,29-/m1/s1 CGIUPYXYUUXSSJ-MVUYGMRSSA-N 26534 (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-4-oxo-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 19 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 40 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26534&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138236 56464971 ZINC40877549 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48457 CN1C(C[C@@]2(C[C@@H]2C(O)=O)C1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1 InChI=1S/C30H25FN2O4/c1-33-26(16-30(29(33)36)15-22(30)28(34)35)19-11-12-27(23(31)13-19)37-17-20-14-25(18-7-3-2-4-8-18)32-24-10-6-5-9-21(20)24/h2-14,22,26H,15-17H2,1H3,(H,34,35)/t22-,26?,30-/m1/s1 INJZRGNTMDWYSJ-YDSPQXFFSA-N 26535 (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-methyl-4-oxo-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 20 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 94 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26535&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138237 56464972 ZINC40896920 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48458 OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1 InChI=1S/C29H24N2O4/c32-27(33)23-15-29(23)16-26(31-28(29)34)19-10-12-21(13-11-19)35-17-20-14-25(18-6-2-1-3-7-18)30-24-9-5-4-8-22(20)24/h1-14,23,26H,15-17H2,(H,31,34)(H,32,33)/t23-,26?,29-/m1/s1 BFZXMIUWGSTUAL-WMKGGLNKSA-N 26536 (1S,3R)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 21 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 143 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26536&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 3EWJ 25138238 56464973 ZINC40891583 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48459 OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccncc2)cc1 InChI=1S/C28H23N3O4/c32-26(33)22-14-28(22)15-25(31-27(28)34)17-5-7-20(8-6-17)35-16-19-13-24(18-9-11-29-12-10-18)30-23-4-2-1-3-21(19)23/h1-13,22,25H,14-16H2,(H,31,34)(H,32,33)/t22-,25?,28-/m1/s1 GYFNSMGKWXLJEX-RVFKSZKCSA-N 26537 (1S,3R)-4-oxo-6-(4-{[2-(pyridin-4-yl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 22 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 673 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26537&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138239 56464974 ZINC40894363 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48460 OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)C(F)(F)F)cc1 InChI=1S/C24H19F3N2O4/c25-24(26,27)20-9-14(16-3-1-2-4-18(16)28-20)12-33-15-7-5-13(6-8-15)19-11-23(22(32)29-19)10-17(23)21(30)31/h1-9,17,19H,10-12H2,(H,29,32)(H,30,31)/t17-,19?,23-/m1/s1 HZAHYVUKQWSJHG-QKLBRSPYSA-N 26538 (1S,3R)-4-oxo-6-(4-{[2-(trifluoromethyl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 23 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 2140 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26538&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138240 56464975 ZINC40891544 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48461 Cc1cc(COc2ccc(cc2)C2C[C@@]3(C[C@@H]3C(O)=O)C(=O)N2)c2ccccc2n1 InChI=1S/C24H22N2O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-30-17-8-6-15(7-9-17)21-12-24(23(29)26-21)11-19(24)22(27)28/h2-10,19,21H,11-13H2,1H3,(H,26,29)(H,27,28)/t19-,21?,24-/m1/s1 UULCKRRPZZHFCH-PBFVZKOQSA-N 26539 (1S,3R)-6-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-4-oxo-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 24 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3070 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26539&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138241 56464976 ZINC40891546 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48462 OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2cccnc2)cc1 InChI=1S/C28H23N3O4/c32-26(33)22-13-28(22)14-25(31-27(28)34)17-7-9-20(10-8-17)35-16-19-12-24(18-4-3-11-29-15-18)30-23-6-2-1-5-21(19)23/h1-12,15,22,25H,13-14,16H2,(H,31,34)(H,32,33)/t22-,25?,28-/m1/s1 HQSSUNUKWAZRMC-RVFKSZKCSA-N 26540 (1S,3R)-4-oxo-6-(4-{[2-(pyridin-3-yl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 25 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3220 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26540&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138242 56464977 ZINC40877039 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48463 COC(=O)[C@H]1C[C@@]11CC(N(C)C1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1 InChI=1S/C31H27FN2O4/c1-34-27(17-31(30(34)36)16-23(31)29(35)37-2)20-12-13-28(24(32)14-20)38-18-21-15-26(19-8-4-3-5-9-19)33-25-11-7-6-10-22(21)25/h3-15,23,27H,16-18H2,1-2H3/t23-,27?,31-/m1/s1 PRCSUQWRLKQCIO-JMWAVFDPSA-N 26541 methyl (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-methyl-4-oxo-5-azaspiro[2.4]heptane-1-carboxylate::methyl ester-spirocyclopropyl compound, 26 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens >50000 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2008.11.034 10.7270/Q2JH3JH7 19054672 aid1798700 Guo, Z; Orth, P; Wong, SC; Lavey, BJ; Shih, NY; Niu, X; Lundell, DJ; Madison, V; Kozlowski, JA Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26541&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138243 56464978 ZINC40401314 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48464 CC#CCOc1ccc(cc1)S(=O)(=O)N1CC(S)C1 InChI=1S/C13H15NO3S2/c1-2-3-8-17-11-4-6-13(7-5-11)19(15,16)14-9-12(18)10-14/h4-7,12,18H,8-10H2,1H3 DDWORVNNZSFIOY-UHFFFAOYSA-N 26542 1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}azetidine-3-thiol::thiol-arylsulfonamide, 4a Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 13 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26542&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138244 56464979 ZINC28820427 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48465 CC#CCOc1ccc(cc1)S(=O)(=O)N1CC[C@@H](S)C1 InChI=1S/C14H17NO3S2/c1-2-3-10-18-12-4-6-14(7-5-12)20(16,17)15-9-8-13(19)11-15/h4-7,13,19H,8-11H2,1H3/t13-/m1/s1 BLIQFUCBRCDFAI-CYBMUJFWSA-N 26543 (3R)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrrolidine-3-thiol::BMCL1844 Compound 2::thiol-arylsulfonamide, 4b Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 28 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26543&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 16739287 56464980 ZINC03818633 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48466 CC#CCOc1ccc(cc1)S(=O)(=O)N1CC[C@H](S)C1 InChI=1S/C14H17NO3S2/c1-2-3-10-18-12-4-6-14(7-5-12)20(16,17)15-9-8-13(19)11-15/h4-7,13,19H,8-11H2,1H3/t13-/m0/s1 BLIQFUCBRCDFAI-ZDUSSCGKSA-N 26544 (3S)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrrolidine-3-thiol::thiol-arylsulfonamide, 4c Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 33 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26544&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 283 2OI0 9861547 56464981 DB06943 ZINC16052299 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48467 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCC(S)C1 InChI=1S/C15H19NO3S2/c1-2-3-11-19-13-6-8-15(9-7-13)21(17,18)16-10-4-5-14(20)12-16/h6-9,14,20H,4-5,10-12H2,1H3 NVJUVGMOOGFJLZ-UHFFFAOYSA-N 26545 1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}piperidine-3-thiol::Racemic::thiol-arylsulfonamide, 4d Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 55 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26545&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138245 56464982 ZINC28820435 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48468 S[C@@H]1CCN(C1)S(=O)(=O)c1ccc(OCC#CCN2CCCCC2)cc1 InChI=1S/C19H26N2O3S2/c22-26(23,21-14-10-18(25)16-21)19-8-6-17(7-9-19)24-15-5-4-13-20-11-2-1-3-12-20/h6-9,18,25H,1-3,10-16H2/t18-/m1/s1 WQXRLQZSXRETEV-GOSISDBHSA-N 26546 (3R)-1-[(4-{[4-(piperidin-1-yl)but-2-yn-1-yl]oxy}benzene)sulfonyl]pyrrolidine-3-thiol::thiol-arylsulfonamide, 12a Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 530 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26546&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138246 56464983 ZINC28820467 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48469 CN1CCN(CC#CCOc2ccc(cc2)S(=O)(=O)N2CC[C@@H](S)C2)CC1 InChI=1S/C19H27N3O3S2/c1-20-11-13-21(14-12-20)9-2-3-15-25-17-4-6-19(7-5-17)27(23,24)22-10-8-18(26)16-22/h4-7,18,26H,8-16H2,1H3/t18-/m1/s1 KIAJGNVJPITLFF-GOSISDBHSA-N 26547 (3R)-1-[(4-{[4-(4-methylpiperazin-1-yl)but-2-yn-1-yl]oxy}benzene)sulfonyl]pyrrolidine-3-thiol::thiol-arylsulfonamide, 12b Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 3400 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26547&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138247 56464984 ZINC28820445 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48470 CC#CCNc1ccc(cc1)S(=O)(=O)N1CC(S)C1 InChI=1S/C13H16N2O2S2/c1-2-3-8-14-11-4-6-13(7-5-11)19(16,17)15-9-12(18)10-15/h4-7,12,14,18H,8-10H2,1H3 WRNABYIRRHWIRI-UHFFFAOYSA-N 26548 1-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}azetidine-3-thiol::thiol-arylsulfonamide, 16a Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 11 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26548&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138248 56464985 ZINC28820447 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48471 CC#CCNc1ccc(cc1)S(=O)(=O)N1CC[C@@H](S)C1 InChI=1S/C14H18N2O2S2/c1-2-3-9-15-12-4-6-14(7-5-12)20(17,18)16-10-8-13(19)11-16/h4-7,13,15,19H,8-11H2,1H3/t13-/m1/s1 PWEZTWADIIJUFX-CYBMUJFWSA-N 26549 (3R)-1-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}pyrrolidine-3-thiol::thiol-arylsulfonamide, 16b Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 5 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26549&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138249 56464986 ZINC28820451 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48472 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NO InChI=1S/C13H16N2O5S/c1-3-4-9-20-11-5-7-12(8-6-11)21(18,19)15(2)10-13(16)14-17/h5-8,17H,9-10H2,1-2H3,(H,14,16) DQDPBMDGDOPPLK-UHFFFAOYSA-N 26550 2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamido}-N-hydroxyacetamide::BMCL1844 Compound 1::CHEMBL321556::butynyloxy containing compound, 1 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 10 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26550&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 9948666 56464987 CHEMBL321556 ZINC13537375 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48473 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CCS InChI=1S/C13H17NO3S2/c1-3-4-10-17-12-5-7-13(8-6-12)19(15,16)14(2)9-11-18/h5-8,18H,9-11H2,1-2H3 IEFFRLNSCQIVBY-UHFFFAOYSA-N 26551 4-(but-2-yn-1-yloxy)-N-methyl-N-(2-sulfanylethyl)benzene-1-sulfonamide::butynyloxy containing compound, 2 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 56 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26551&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138250 56464988 ZINC28820720 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48474 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)C[C@H](C)S InChI=1S/C14H19NO3S2/c1-4-5-10-18-13-6-8-14(9-7-13)20(16,17)15(3)11-12(2)19/h6-9,12,19H,10-11H2,1-3H3/t12-/m0/s1 VRZXDGCRBIXJPJ-LBPRGKRZSA-N 26552 4-(but-2-yn-1-yloxy)-N-methyl-N-[(2S)-2-sulfanylpropyl]benzene-1-sulfonamide::butynyloxy containing compound, 3 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 27 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.01.064 10.7270/Q2DV1H67 17289381 aid1798701 Govinda Rao, B; Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Tian, SK; Saunders, JO Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26552&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138251 56464989 C01525 ZINC28820841 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48494 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NO InChI=1S/C13H16N2O5S/c1-3-4-9-20-11-5-7-12(8-6-11)21(18,19)15(2)10-13(16)14-17/h5-8,17H,9-10H2,1-2H3,(H,14,16) DQDPBMDGDOPPLK-UHFFFAOYSA-N 26550 2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamido}-N-hydroxyacetamide::BMCL1844 Compound 1::CHEMBL321556::butynyloxy containing compound, 1 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 10 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26550&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 9948666 56464987 CHEMBL321556 ZINC13537375 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48495 CC#CCOc1ccc(cc1)S(=O)(=O)N1CC[C@@H](S)C1 InChI=1S/C14H17NO3S2/c1-2-3-10-18-12-4-6-14(7-5-12)20(16,17)15-9-8-13(19)11-15/h4-7,13,19H,8-11H2,1H3/t13-/m1/s1 BLIQFUCBRCDFAI-CYBMUJFWSA-N 26543 (3R)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrrolidine-3-thiol::BMCL1844 Compound 2::thiol-arylsulfonamide, 4b Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 28 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26543&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 16739287 56464980 ZINC03818633 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48496 CC#CCOc1ccc(cc1)S(=O)(=O)CCS InChI=1S/C12H14O3S2/c1-2-3-8-15-11-4-6-12(7-5-11)17(13,14)10-9-16/h4-7,16H,8-10H2,1H3 ARGOMDGUBFAFLZ-UHFFFAOYSA-N 26553 2-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}ethane-1-thiol::thiol-aryl sulfone, 8a Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 8 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26553&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138252 56464990 ZINC28979334 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48497 CC#CCOc1ccc(cc1)S(=O)(=O)CCCS InChI=1S/C13H16O3S2/c1-2-3-9-16-12-5-7-13(8-6-12)18(14,15)11-4-10-17/h5-8,17H,4,9-11H2,1H3 CARKQNSZFCLNKM-UHFFFAOYSA-N 26554 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1-thiol::CHEMBL402747::thiol-aryl sulfone, 8b Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 10 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26554&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 440 3B92 23627203 56464991 CHEMBL402747 DB07079 ZINC24961483 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48498 CC#CCNc1ccc(cc1)S(=O)(=O)CCS InChI=1S/C12H15NO2S2/c1-2-3-8-13-11-4-6-12(7-5-11)17(14,15)10-9-16/h4-7,13,16H,8-10H2,1H3 LRESJQHCTORZKX-UHFFFAOYSA-N 26555 2-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}ethane-1-thiol::thiol-aryl sulfone, 13 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 2 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26555&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138253 56464992 ZINC28979364 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48499 CC#CCNc1ccc(cc1)S(=O)(=O)CCCS InChI=1S/C13H17NO2S2/c1-2-3-9-14-12-5-7-13(8-6-12)18(15,16)11-4-10-17/h5-8,14,17H,4,9-11H2,1H3 ROMWCNAWMYPXJK-UHFFFAOYSA-N 26556 3-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}propane-1-thiol::thiol-aryl sulfone, 16 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 4.5 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26556&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138254 56464993 ZINC28979366 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48500 CC#CCOc1ccc(cc1)S(=O)(=O)C1CCC(S)C1 InChI=1S/C15H18O3S2/c1-2-3-10-18-12-4-7-14(8-5-12)20(16,17)15-9-6-13(19)11-15/h4-5,7-8,13,15,19H,6,9-11H2,1H3 MGTOBLJTRIDRIH-UHFFFAOYSA-N 26557 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}cyclopentane-1-thiol::thiol-aryl sulfone, 23 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 50 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26557&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138255 56464994 ZINC28979399 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48501 CC#CCOc1ccc(cc1)S(=O)(=O)C1CCCC(S)C1 InChI=1S/C16H20O3S2/c1-2-3-11-19-13-7-9-15(10-8-13)21(17,18)16-6-4-5-14(20)12-16/h7-10,14,16,20H,4-6,11-12H2,1H3 MWJINRBCZKGRGC-UHFFFAOYSA-N 26558 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}cyclohexane-1-thiol::thiol-aryl sulfone, 24 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 30 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26558&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138256 56464995 ZINC62233031 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 48502 CC#CCNc1ccc(cc1)S(=O)(=O)C1CCCC(S)C1 InChI=1S/C16H21NO2S2/c1-2-3-11-17-13-7-9-15(10-8-13)21(18,19)16-6-4-5-14(20)12-16/h7-10,14,16-17,20H,4-6,11-12H2,1H3 HVQVSRYAFQSVJD-UHFFFAOYSA-N 26559 3-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}cyclohexane-1-thiol::thiol-aryl sulfone, 25 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens 17 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.11.014 10.7270/Q2930RH8 18054488 aid1798703 Bandarage, UK; Wang, T; Come, JH; Perola, E; Wei, Y; Rao, BG Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26559&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 25138257 56464996 ZINC62233042 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 200662 NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cc(cs1)-c1ccccc1 InChI=1S/C29H31N3O7S/c30-28(38)22(11-14-26(34)35)32-29(39)23(12-15-27(36)37)31-25(33)13-8-18-6-9-20(10-7-18)24-16-21(17-40-24)19-4-2-1-3-5-19/h1-7,9-10,16-17,22-23H,8,11-15H2,(H2,30,38)(H,31,33)(H,32,39)(H,34,35)(H,36,37)/t22-,23+/m1/s1 MMIHYNVQXYWTFM-PKTZIBPZSA-N 92443 MMP Inhibitor, 3::Thiophene derivative, compound 36::US8691753, 97 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens >10000 6.8 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M110.139634 10.7270/Q25X27HV 20817735 aid1799790 Devel, L; Garcia, S; Czarny, B; Beau, F; LaJeunesse, E; Vera, L; Georgiadis, D; Stura, E; Dive, V Commissariat à l'Energie Atomique http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92443&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 50991679 160844940 ZINC89469592 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 200674 NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)C(Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1)CP(O)(=O)c1ccc(Br)cc1 InChI=1S/C35H35BrClN4O10P/c36-24-8-10-27(11-9-24)52(49,50)19-23(34(47)40-29(13-15-32(44)45)35(48)39-28(33(38)46)12-14-31(42)43)17-26-18-30(41-51-26)21-6-4-20(5-7-21)22-2-1-3-25(37)16-22/h1-11,16,18,23,28-29H,12-15,17,19H2,(H2,38,46)(H,39,48)(H,40,47)(H,42,43)(H,44,45)(H,49,50)/t23?,28-,29+/m1/s1 PTUCPHGSAFOJAU-HHIKFEJTSA-N 92441 RXP470, 1::RXP470, Compound 4 Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q] Homo sapiens >10000 6.8 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M110.139634 10.7270/Q25X27HV 20817735 aid1799790 Devel, L; Garcia, S; Czarny, B; Beau, F; LaJeunesse, E; Vera, L; Georgiadis, D; Stura, E; Dive, V Commissariat à l'Energie Atomique http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2400&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92441&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17+%5B215-477%2CS266A%2CN452Q%5D&column=ki&startPg=0&Increment=50&submit=Search 70701992 160844938 ZINC96142386 1 RADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNKV 1ZXC,2A8H,2I47,2OI0,3B92,3CKI,3E8R,3EDZ,3EWJ,3G42 Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226